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    Schizophrenia&

    Other Psychotic Disorders

    Chapter 20

    Melinda Hermanns,MSN, RN, BC

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    Schizophrenia

    Neurological disease thataffects a persons perception,

    thinking, language, emotion,and social behavior.

    Occupies approximately 50% ofall hospital beds and 35-50% ofthe homeless population

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    Schizophrenia

    Lifetime Prevalence: 1% worldwide

    Typical Age ofOnset: late teens

    and early 20s.

    Men and women equal

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    Theories

    Cause unknown most likely aresult of inherited geneticfactors and non-geneticfactors

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    Theories (contd)

    Neuroanatomical Studies -structural brain abnormalities:

    Cerebral ventriclesCortical atrophy

    Atrophy of frontal lobe

    PET ScanMRI

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    Non-genetic Risk Factors

    Birth and Pregnancy

    Complications

    Stress-Related Theories

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    Bleulers 4 As

    Affect

    Associative Looseness

    Autism

    Ambivalence

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    Prodromal /Early Symptoms

    Symptoms one month to one yearbefore psychotic break

    Person feels something strange orweird is happening to them

    Misinterprets things in theenvironment

    Feelings of rejection, lack of self-respect, loneliness,hopelessness,isolation, withdrawal, and inability

    to trust others.

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    DSM-IV-TRDiagnosis

    Schizophrenia Must exhibit two or more of the

    following, each present for at least a 1-

    month period:delusions

    hallucinations

    disorganized speechgrossly disorganized

    negative symptoms (flat affect)

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    Assessing Symptoms

    Symptoms may be classified as

    Positive attention getter symptoms i.e.hallucinations, delusions, bizarre behavior,

    disorganized speech Negative crippling symptoms i.e. apathy,

    lack of motivation, anhedonia

    Cognitive - i.e. difficulty with attention,

    memory, and problem solving Disorganized i.e. disorganized speech,inappropriate affect

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    Alterations in Thinking

    Delusions

    Ideas of Reference

    Persecution

    Grandiosity

    Bodily Functions

    Jealousy

    Control

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    Symptoms

    thoughtbroadcasting

    thoughtinsertion

    thought

    withdrawalbeing

    controlled

    LooseAssociation

    Neologisms Concrete

    Thinking

    Echolalia ClangAssociation

    Word Salad

    Review

    Table 22-6,

    page 643

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    Alterations in Perceiving

    Hallucinations - auditory, visual, olfactory,gustatory, and tactile

    90% of schizophrenics experiencehallucinations - auditory most common

    Difference between Illusions andHallucinations

    Depersonalization and Derealization (loss ofego boundaries)

    Bizarre BehaviorBe familiar with the terms in Table 22-4,

    page 636

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    Negative Symptoms

    Develop over time

    May not be detected (masked by positive

    symptomsNegative symptoms include: poverty of

    speech content, thought blocking, anergia,

    anhedonia, affective blunting, and lack ofavolition.

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    Associated Symptoms

    Depression and Suicide

    Water Intoxication

    Substance Abuse

    Violent Behavior

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    Nursing Diagnosis

    Multifaceted approach

    Table 20 5: Potential Nursing Diagnoses

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    Outcome Criteria

    Phase I: Acute Phase - crisis

    intervention

    Phase II: Maintenance

    Phase III: Stable

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    Planning

    Hospitalization

    Identify long-term care needs

    Identify and provide proper referrals For patient and family follow-up

    Living arrangements, economic resources, socialsupports, family relationships, vulnerability to stress

    Referral to community agencies Example:Andrews Center MHMR (learn about illness,medications, and relapse prevention skills)

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    Intervention

    Treatment Focus at Different Phases of

    Schizophrenia Table 20 -7, p. 540

    SAFETY First - Verbal Deescalation, followed by

    Chemical Restraints (antipsychotics), then

    as last resorts: Physical Restraints, andSeclusion may be indicated.

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    Communication Skills

    Table 20 8, p. 541

    What to do if:

    The patient is hallucinating The patient is experiencing delusions

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    Schizoaffective Disorder

    Mixture of Schizophrenic and Affectivesymptoms

    I.e. alterations in mood as well as disturbancesin thought

    Thought by some to be a severe form ofBipolar (Varcarolis, 1998)

    Treatment: Lithium used with antipsychotictherapy for treatment of manic symptoms

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    Psychopharmacology

    Typical (Traditional) Antipsychotics

    target the positive symptoms

    Older drugs Watch for signs of EPS

    Atypical (Novel) Antipsychotics

    diminish the positive and negative

    symptoms

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    Typical Antipsychotic

    Medications Thorazine

    Mellaril

    Stelazine

    Trilafon

    Serentil

    Prolixin

    Navane

    Haldol

    (Haloperidol

    and Haloperidoldeconate)

    Loxapine

    Moban

    KNOW SIDE EFFECTS

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    Side Effects of Antipsychotics

    Anticholinergic Symptoms

    Extrapyramidal Symptoms (EPS)

    1. Pseudoparkinsonism2. Acute dystonic reactions

    -Opisthotonos

    -Oculogyric Crisis

    3. Akathisia

    4. Tardive Dyskinesia

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    Atypical Antipsychotics

    Advantage over typical: alleviate bothpositive and negative symptoms(improvement of quality of life)

    Clozapine (Clozaril) - agranulocytosisand seizures

    LOWER SIDE EFFECTS:

    Risperidone (Risperdal)

    Olanzapine (Zyprexa)

    Quetiapine (Seroquel)

    Ziprasidone (Geodon)

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    Adjuncts to Antipsychotic Therapy

    Antidepressants

    Antimanic Agents

    Benzodiazepines

    ECT

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    Sub-types of Schizophrenia

    Paranoid Type

    Disorganized Type

    Catatonic Type

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    Subtype: Paranoid

    Any intense and strongly defendedirrational suspicion

    Most common symptoms -hallucination and delusions

    Defense Mechanism - Projection

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    Subtype: Disorganized Type

    Most regressed and sociallyimpaired

    Symptoms - loose association,inappropriate affect, bizarremannerisms, incoherent speech

    and withdrawn Onset?

    Prognosis

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    Subtype: Catatonia

    Abnormal motor behavior

    Be familiar with other symptoms

    Prognosis?

    Physical Needs are a Priority

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    Nursing Interventions for

    Schizophrenic Subtypes Be familiar with the following in each of

    the subtypes:

    Communication Guidelines

    Self-Care Needs

    Milieu Needs

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    FOR SCHIZOPHRENIA &

    SCHIZOPHRENIA SUB-TYPES

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    Patient and Family Health Teaching

    Educate patient and family about illness

    Assist patient in improving his or her ability to

    solve problems related to environmental stress Teach the patient coping strategies

    Assist family and patient to identify sources for

    ongoing support

    TABLE 20 10, p. 544

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    Case Management

    DISCHARGE PLANNING

    Partial Hospitalization

    Halfway Houses

    Day Treatment Programs Group Therapy

    Supervised Activities Individual Counseling

    Specialized Training and Rehabilitation

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    Therapy

    Individual

    Supportive

    Group

    Family

    Counseling

    Psychoeducational

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    Evaluation

    Realistic Goals

    Reassess patients problems

    Active involvement in patients progress

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    Neologism

    Definition: Words a personmakes up that have meaning

    only for that person, it is oftenpart of a delusional system.

    Example: I am afraid to go to

    the hospital because the norksare looking for me.

    Back

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    Echolalia

    Definition - mimicking or imitating

    the speech of another person.

    Example: The nurse says to thepatient, Tell me your name. The

    patient responds, Tell me your

    name, tell me your name.Back

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    Word Salad

    Definition: Mixture of wordsand phrases that have no

    meaning. Example: I am fineapple

    pieno salefurniture

    storetake it slowcellardoor Back

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    Concrete Thinking

    What brought you here to thehospital?

    The cab People in glass houses shouldnt

    through stones.

    Dont throw stones or the windowswill break.

    ANSWERS ARE LITERAL

    Back

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    BE FAMILIAR WITH:

    thought broadcasting - the

    belief that ones thoughts can

    be heard by others

    Back

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    Thought Insertion

    thought insertion - the belief

    that thoughts from other people

    are being inserted into onesmind

    BACK

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    BE FAMILIAR WITH:

    thought withdrawal - the belief

    that thoughts have been

    removed from ones mind by anoutside agency.

    Back

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    Delusions of Being Controlled

    Delusions of being controlled

    belief that ones body or mind is

    controlled by an outside agency

    BACK

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    Common Side Effects

    Anti-cholinergic

    Sedation

    Orthostatic Hypotension

    Lowered Seizure Threshold

    Extrapyramidal Side Effects (EPS) Less Common NMS

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    PET ScanDiscordant Monozygotic

    Twins

    Frontal

    LobeFrontal

    Lobe

    BACK

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    BACK

    Magnetic Resonance Imaging

    (MRI)