science 30 unit a ch 1 suggested answers...like a chambered furnace for the body. there were lots of...
TRANSCRIPT
Unit A Maintaining Health
Chapter 1: Circulation and Immunity
Practice, page 9
1. Heart tHeorIes
Person theory about the Heart Limitations of the theory
Galen
The heart is divided in two halves, blood is produced in the liver, and blood moves like ocean tides.
Evidence was gathered only from animal dissections, and there was no experimental testing to support the theory.
Leonardo da Vinci
He drew anatomically correct sketches of the heart. The heart is like a chambered furnace for the body.
There were lots of observations on dead bodies, but human cadaver dissections were not officially permitted, so he did not share his findings.
William Harvey
He had a modern view of the heart. Blood is re-pumped in a closed system of vessels.
Without the technology of the microscope, Harvey could not see capillaries to prove that blood moved from arteries to veins.
2. Solution: strokevolume mL/beat(forfemales)
mL /beat 1L100
=
= ¥
60
6000 mL
L/beat
heartrate beats/minute
cardiacoutput
==
0 060
68
.
== ?
cardiacoutput strokevolume heartrate
Lbeat
= ( ) ¥ ( )
=ÊËÁ
0 060. ˆ̂¯̃
¥( )
==
68
4 08
4 1
beats
min
L/min
L/min
.
.
Thecardiacoutputis4.1L/min.
3. Solution: cardiacoutput L/min
volumepumpedinoneyear
volume
==
4 08.
?
pumpedinoneyear Lmin
minh
hd
da
= ¥ ¥ ¥ =4 08 60 24 365 252 1. .. ¥¥106 L/a
Thevolumepumpedinoneyearis2.1¥106L/a.
4. Sincetheaveragecardiacoutputisjustunder5L/minandtheaveragehumanhas5Lofblood,thismeansthatittakesaboutoneminutetocirculateallthebloodinthebody.
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5. strokevolume mL/beat formales
mL /beat L mL
h
= ( )= ¥
70
70 11000
eeartrate beats/minute
cardiacoutput
==
180
?
cardiacoutput strokevolume heartrate
L
beat
= ( ) ¥ ( )
=( )
¥0 070. 1180
12 6
13
beatsmin
L/min
L/min
==
.
Thecardiacoutputis13L/min.
6. a. Valuesforcardiacoutputwillvaryforeachstudent.Thefollowingsamplecalculationshowstheresultsforafemalestudentwitharestingheartrateof71beatsperminute.
Solution: strokevolume mL/beat forfemales
mL /beat 1L1000
= ( )= ¥
60
60mmL
L/beat
heartrate beats/minute
cardiacoutput
===
0 060
71
.
?
cardiacoutput strokevolume heartrate
L
beats
= ( ) ¥ ( )
=( )0 060.
¥¥( )
==
71
4 26
4 3
beats
min
L/min
L/min
.
.
Thecardiacoutputis4.3L/min.
b. Answerswillvary.Thefollowingsamplecalculationfollowsfromquestion6.a.andshowstheresultsforafemalestudentwitharestingheartrateof71beatsperminute.
rate cardiacoutput
L/min
timetofillabarrel
===
4 26.
?
timetofillabarrelvolumeofbarrel
rateL
L
=( )
=( )213
4 26. // min= 50min
Itwouldtakeapump50mintofillthebarrelifitwasoperatingatthesamerateasthecardiacoutput.
c. Iftheheartratedoubles,thenthecardiacoutputdoublesifthestrokevolumeremainsconstant.Thismeansthattherateofpumpingintothesamebarrelshouldalsodouble.Theoveralleffectisthatthebarrelwouldfillinonlyhalfthetimecalculatedinquestion6.b.Byusingthesampledataprovidedin6.a.and6.b.,thebarrelwouldfillin25minutes.
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Practice, page 13
7. Yourdiagramshouldbesimilartothefollowing.
superior vena cava from upper body
inferior vena cava from lower body
aorta to lower body
pulmonary artery to right lung
pulmonary artery to left lung pulmonary artery
pulmonary veins from right lung
pulmonary veins from left lung
semilunar valve
right atrium
aorta
left atrium
rightventricle
left ventricle artrioventricular
valve
semilunar valve
artrioventricular valve
septum
to lo
w
er body to
u
pper body
1
6
2
4
3
5
the Human Heart
Practice, page 16
Resultsforquestions8and9willvarydependingonstudentage.Sampledatafora17-year-oldstudentfollows.
8. Findyourmaximumheartratebysubtractingyouragefrom220.
220-17=203beatsperminute
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10. Aspeoplegetolder,theirtargetheartrateswilldecreaseforeachcategory.
1.1 Questions, page 19
Knowledge
1. Beginningwiththevenacavae,theorderofthestructuresofthecardiovascularsystemthroughwhichbloodflowsisasfollows:venacavae,rightatrium,rightventricle,lungs,leftatrium,leftventricle,aorta,andbody.
2. a. IV Thepulmonaryveinsreceiveoxygenatedbloodfromthelungs. b. II Theaortasendsoxygenatedbloodtothebody. c. V Thesemilunarvalvepreventsthebackflow
ofbloodintotheheart. d. VI Theseptumseparatestherightandleft
halvesoftheheart. e. I Thevenacavaecollectsdeoxygenated
bloodfromthebody.
I
II
III
IV
V
VI
9. Studentswillusetheiranswersfromquestion8tofinishthistable.
Your target Heart rate
Personal Health Goal Heart rate
50% of 203 bpm = 102 bpm
maintain fitness level
60% of 203 bpm = 122 bpm
increase fat burning or weight loss
70% of 203 bpm = 142 bpm
increase cardiovascular endurance
80% of 203 bpm = 162 bpm
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applying Concepts
3. a. strokevolume mL/beat
mL /beat L mL
L/b
=
= ¥
=
100
100 11000
0 100. eeat
heartrate beats/minute rest
heartrate beats/m
= ( )=
50
115 iinute lightexercise
heartrate beats/minute high-inte
( )=180 nnsityexercise
cardiacoutput
( )= ?
atrest: cardiacoutput strokevolume heartrate
Lbeat
= ( ) ¥ ( )
= ¥0 100 50. beats
L/min
( )
=min
.5 0
Thecardiacoutputis5.0L/minfortheathleteatrest.
lightexercise: cardiacoutput strokevolume heartrate
L
beat
= ( ) ¥ ( )
=( )
¥0 100. 1115
11 5
beats
L/min
( )
=min
.
Thecardiacoutputis11.5L/minfortheathletedoinglightexercise.
high-intensityexercise: cardiacoutput strokevolume heartrate
L
beats
= ( ) ¥ ( )
=( )0 100.
¥¥( )
=
180
18 0
beats
L/min
min
.
Thecardiacoutputis18.0L/minfortheathletedoinghigh-intensityexercise.
b. Regularcardiovascularexerciseincreasestheelasticityofthehearttissue—thisgivestheheartagreatercapacitytoexpandand,therefore,alargerstrokevolume.Sincethestrokevolumeislarger,anincreasedvolumeofbloodispumpedtothebodyduringeachoftheheart’scycles,sotheathlete’sbodycangetthenecessaryamountofbloodwithfewerheartbeats.
Aninactivepersontendstohaveaheartwithlesselastictissue,sothishearthasadecreasedabilitytoexpandand,therefore,areducedstrokevolume.Thisreductioninbloodvolumepumpedtothebodyduringeachoftheheart’scyclesmeansthatittakesmoreheartbeatseveryminutetosupplythebodywiththerequiredamountofblood.
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Practice, page 23
11. a. Partsofthecirculatorysystemthatcorrespondtoacommunity’swaterpipes,sewagepipes,pump,andwaterare,inorder,thearteries,veins,heart,andblood.
b. Onelimitationisthatthecirculationofbloodinthehumanbodyisaclosedsystembecauselargeamountsofblooddonotnormallyenterandleavethesystem.Acommunity’swatersystemisnotaclosedsystem.Cleandrinkingwatercomesfromtheenvironmentandthenreturnstotheenvironment.Inotherwords,manycommunitiesmayusethesameriversystemasawatersource,butundernormalcircumstancesmanypeopledonotgettheirbloodfromthesamecommonsource.
Anotherlimitationoftheanalogyisthatthebodydoesnothavetheequivalentofawatersystem’sreservoir.Thereisnoplaceinthebodythatcontainsavastpoolofbloodthatcanbestoredovermanymonths.
12. a. Thepulmonaryarteriescarryoxygen-poorbloodfromthehearttothelungs. b. Theaortaisthebody’slargestartery. c. Thecoronaryarteriescarryoxygen-richbloodfromtheaortatonourishthehearttissues. d. Thepulmonaryveinscarryoxygen-richbloodfromthelungstotheheart. e. Thevenaecavaecarryoxygen-poorbloodfromthebody’stissuestotheheart.
13. Arteriesalwayscarrybloodawayfromtheheartandveinsalwayscarrybloodtotheheart.Thisisalwaystrue.However,itisnotalwaystruethatarteriescarryoxygen-richbloodandveinscarryoxygen-poorblood.Thepulmonaryarteriescarryoxygen-poorbloodfromtherightventricletothelungs.Thepulmonaryveinscarryoxygen-richbloodfromthelungsbacktotheheart.
14. Itisimportantforthewallsofcapillariestobethinsothatoxygenandothersubstancesneededbycellscandiffusefromthebloodtothetissuecells.Thethinwallsalsoallowcarbondioxideandwastematerialstodiffusefromthetissuecellsintotheblood.
Practice, page 24
15. a. vein b. capillary c. venule d. arteriole e. artery
16. Thecorrectorderisartery,arteriole,capillary,venule,andvein.
17. Ifinactivitymeansthatthemusclesarenotregularlycontracting,thentheveinswillhaveahardertimemovingbloodbacktotheheart,whichmayresultinimpairedcirculation.
18. Thelower-legveinsarethefarthestawayfromtheheartandthebloodinthemhasthelongestwaytotravelbacktotheheart.Gravityalsoplaysaroleheresincewhenyouarestanding,thepathfromthefeettotheheartisstraightup—thisisoppositetothedirectionthatgravitynaturallytendstopullmatter.
Itfollowsthatbloodismorelikelytobesloweddownorpoolinthelowerlegs.Thevalvesinthelegs’veinsarethereforeunderthegreatestamountofstressandmostoftenbecomelesseffective.Thiscanleadtovaricoseveins.
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19. Forastandingperson,thevalvesinthelegveinsareworkingagainstgravity.Ifpeoplespendmuchoftheirdaysontheirfeet,itmeansthatbloodispoolinginthelegsforalongeramountoftime.Thiscanputextrastressonthesevalves.Elevatingthefeetattheendofalongperiodofstandingreducessomeoftheforcefrompooledblooddrawndownwardbygravity.Raisingthefeetalsotakespressureoffthevalves,whichreducestheriskofdevelopingvaricoseveinsorsufferingdamagefromthatcondition.
Conclusion
4. Bloodflowsfromthehandtowardtheheart.Ifbloodispushedagainstthisflow,itpoolsintheveinsatcertainplaces.Theseplacescorrespondwiththevalves.
Practice, page 29
20. a. Thevalueof138issystolicpressure.Thisispressurecreatedbybloodpushingagainstthewallsofthebrachialarterywhentheheart’sventriclesarecontracting.Theelasticfibresinthearterywallsstretchandexpandslightlyinresponsetothispressure.
Whentheheart’sventriclesarerelaxed,aresidualpressureismaintainedasarteriesattempttoreturntotheirpreviousshapebetweencontractionsoftheventricles.Thisdiastolicpressureisrepresentedby96.
b. Theunitforeachofthesepressuresismillimetresofmercury.
c. Bloodpressurevalueshigherthan140/90arecategorizedashighbloodpressurebecausethesevaluesareabnormallyhigh.Thisoftenindicateshealthproblemsthatneedtobetreatedbyaphysician.Sincethevaluesfromtheautomatedmachineareclosetohighbloodpressurelevels,itwouldbewisetomakeanappointmentwithafamilydoctorandhavethesevaluesconfirmed.Itmaynotnecessarilybecauseforconcernbecausethehighvaluescouldbeduetootherfactorsthatmayhavetemporarilyraisedbloodpressurevalues,suchastightclothingaroundthearmwhenthetestwastaken;anxietyornervousness;oreatingordrinkingsomething.
21. Thesourceofresidualpressureistheslightcontractionofthearteries’elasticwallsastheyattemptto
reboundfromtheslightstretchingcausedbythepreviousheartbeat.
22. Severalfactorscausetheblood’sspeedtodropasitpassesthroughthecapillaries.Thetotalcross-sectionalareaofvesselscarryingblooddramaticallyincreasesasthebloodpassesfromarteries,intoarterioles,andthenintocapillarybeds.Sincethereisamuchlargeropeningfortheincomingbloodtopassthrough,theblooddoesnothavetoflowasfastfortheoutputtomatchtheinput.Asimilareffectcanbeobservedifastudentplaceshisorherthumbovertheendofagardenhoseandthenreleasesthethumbtocreatealargeropening.Inthiscase,watercomesoutofthehoseatareducedspeed.ThetoptwophotosfromFigureA1.xxcanbecheckedforfurtherdetails.
Anothereffecthastodowithresistancetothebloodflow.Capillariesaresotinythatbloodcellshavetopasssinglefilethroughthesmallestofthesevessels.Thiscausesadropinpressurethatresultsinaslowingdownofthebloodflow.
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1.2 Questions, page 33
Knowledge
1. Thefollowingtablecomparesarteries,veins,andcapillaries.
arteries Veins Capillaries
description of vessel walls thick-walled and elastic fibre
thinner walls with no elastic fibres
thinnest walls possible—only one cell thick
direction of vessel blood flow in relation to heart
away from heart toward heart from arteries and arterioles, through capillaries, to venules and veins, and back to heart
blood oxygen level in vessel
relatively high level relatively low level higher level at end close to arteries and a lower level at end close to veins
colour in a circulatory system diagram
red blue red at end close to arteries and blue at end close to veins
blood pressure in vessel high pressure very low pressure pressure decreases as blood moves from the end closest to arteries to end closest to vein
valves present no yes no
pulse present yes no no
applying Concepts
2. a. Peoplewithdiabeteswouldnolongerhavetoinjectthemselveswithinsulin.Usinganinhalerwouldbeamuchlesspainfulandinvasivedeliverysystem,andtherewouldbelesschanceofinfectionfrompoorsanitationattheinjectionsiteorscarringfromrepeatedinjections.Intermsofdisposalandsafety,itismuchmoreconvenienttocarryaroundaninhalerthanitistocarrysyringes.
b. Thepathfromfatundertheskinisasfollows:afatcapillaryundertheskin;avenule;avein;thevenacava;therightatrium;therightventricle;thepulmonaryarteries;thelungs;thepulmonaryveins;theleftatrium;theleftventricle;theaorta;severalarteries;anarteriole;andendatacapillarynexttoatargetcellintheliver.
c. Inhaledinsulinwouldtakethefollowingpathfromthelungstoatargetcellintheliver:thelungs;thecapillariesandvenulesoflungtissue;thepulmonaryveins;theleftatrium;theleftventricle;theaorta;severalarteries;anarteriole;andthentoacapillarynexttothetargetlivercell.
d. Theinhaleddeliverysystemwouldbefasterbecausetheneededchemicalwouldnothavetofirsttravelthroughthede-oxygenatedpartsofthecirculatorysystem.Thisquickerdeliverywouldbeanadvantageoverthehypodermicdeliverysystem.
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3. Factorsthatcancauseaperson’sbloodpressuretoincreaseincludeastrongercontractionoftheheart,ahigherheartrate,andalossintheelasticityofthearteries.Higherbloodpressurereadingscanalsobeattributedtoanxietylevel,exercise,agreaterthannormalamountofbloodinvessels,viscosity(thickness)oftheblood,chemicalssuchascaffeineorepinephrine,kidneydisease,oranarrowingofthebloodvesselsduetoapoordiet.
4. Ifanarteryiscut,thegreaterpressureinanarterymeansthatthebloodflowsoutmorequicklyandforcefullythanitwouldinavein.Itfollowsthatthereisagreaterriskofbloodlosswithacutarterythanthereiswithacutvein.
5. Thefollowingillustrationisasketchofacapillarybed.
blood flow
artery
arteriole
Capillary Bedcarbon dioxide and other waste
materials diffuse from tissuecells into blood
oxygen and othermaterials diffuse fromblood into tissue cells
valve
vein
venule
6. Contractingmusclesinthelowerlegshelptomassagethebloodinthelowerlegsbacktowardtheheart.Oncethelegmusclespushthebloodintheveins,thevalvesareabletodirectthisblood.
Practice, page 36
23. sample of bloodprior to placement
in centrifuge
sample of bloodafter removal
from centrifuge
centrifuge
plasma
platelets,white blood cells
red blood cells
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24. a. Plasmacomprisesabout55%ofbloodvolume. b. Redbloodcellsmakeupalmost45%ofthetotalvolumeofblood. c. Plateletsandwhitebloodcellscompriselessthan1%ofthetotalvolumeofblood.
Practice, page 38
25. a. Inconditionsofextremefatigue,cancerpatientsbenefitfromatransfusionofredbloodcells.
b. Spinningasampleofwholebloodinacentrifugecouldseparatethewholebloodintoredbloodcellsandothercomponents.
26. a. Whitebloodcellsonlylivefrom13to20days,whileredbloodcellsliveabout120days.Therefore,morewhitecellsneedtobemadebecausetheydon’tlivenearlyaslongasredcells.
b. Whitebloodcellsacttodefendthebodyagainstdiseasesandotherforeigninvaders.Mostdisease-causingagentstendtobefoundinthefluidspacesbetweentissuecells,sothisisalsowherewhitebloodcellstendtobe.Sinceabloodtestonlycountsthenumberofwhitebloodcellsinthebloodstream,thewhitecellsoutsideofthebloodstreamarenotincluded.
Practice, pages 40 and 41
27. ThebloodcomponentsthatbestcorrespondtobagsI,II,andIIIare,respectively,redbloodcells,plasma,andplatelets.
28. Ifburnvictimsarehighlysusceptibletodehydration,thebloodcomponentthatbestaddressesthisproblemisplasma,duetoitshighwatercontent.
29. Topreventuncontrollableinternalbleeding,plateletsareoftengiventocancerpatientsaftertheyreceiveradiationtherapy.
30. Everytimeyoudonatewholeblood,thisproductcanbeputinacentrifugeandseparatedintoredbloodcells,plasma,andplatelets.Eachoneofthesethreecomponentscanthenbeusedtohelpanotherpersonandpossiblysavealife.
1.3 Questions, page 41
Knowledge
1. a. Thefourcomponentsofbloodfrommostabundanttoleastabundantareplasma,redbloodcells,whitebloodcells,andplatelets.
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b. Thefollowingdiagramillustrateseachcomponentofquestion1.a.
red blood cell
white blood cell
platelet
plasma
2. a. Slidenumber6fromthepatientwithneutrophiliahasmorewhitebloodcellsthanthepatientwithhealthyblood.
b. Thepatientwithneutrophiliaislikelysufferingfromaninfection.
applying Concepts
3. Carbonmonoxidehasamuchgreateraffinityforhemoglobinthandoesoxygen,socarbonmonoxidewillpreferentiallybindtohemoglobinandformastablebond.Asaresult,ifyouinhaleevenlowconcentrationsofcarbonmonoxide,morehemoglobincombineswithcarbonmonoxidethandoesoxygen.Ifcarbonmonoxideistakingtheplaceofoxygenontheredbloodcells,thatmeansthatthebloodcannottransportneededoxygentothebody’scells.Apersoncouldsuffocateeventhoughheorsheisabletobreathenormally.
4. Anticoagulantsthatthinbloodmakeiteasierforbloodtoflowthroughdamagedorconstrictedbloodvessels.
5. a. Havingimproperlyfunctioningwhitebloodcellsmeansthatthepersonisnotabletofightoffdisease-causingorganisms.
b. Atransplantofhealthybonemarrowmeansthathealthyandnormallyfunctioningwhitebloodcellswillbeproduced.
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6. Atthetimethistextbookwaspublished,theCanadianBloodServicesusesthesecriteriatodetermineeligibilityfordonatingblood:
• Youmusthaveidentificationcontainingyourfullnameandsignatureorfullnameandphotograph.
• Youmustbeatleast17yearsold.
• Youmustweighatleast50kg(110pounds).
• Ifyouhavepreviouslydonatedblood,atleast56daysmusthavepassedsinceyourlastdonation.
• Youmustbeingoodhealthandfeelingwell.Youshouldhavehadsomethingtoeatandbewellrested.Ahemoglobintestonyourbloodwillbedoneattheclinic,andasampleofyourbloodmustpassthistest.
• Atthetimeofthedonation,youwillbeaskedanumberofquestionsrelatedtoyoursuitabilitytogiveblood.Thesequestionswillincludewhetheryoucurrentlyhaveacold,ifyouhavebeentothedentistrecently,orifyouhaveanybodypartpierced.
Practice, page 43
31. ItisnowknownthatscurvyisduetoinsufficientamountsofvitaminCinpeople’sdiet.ThemainsourceofvitaminCfortheearlyEuropeanswasfreshfruitandvegetables.Atthattimeitwasraretofindtheseitemsaboardthewoodensailingshipsthatventuredintonorthernwaters.
32. Inuitpeopleneversufferedfromscurvybecausetheirdietsincludedmaktaaq,asnackconsistingofwhaleskinwithanattachedthinlayerofblubber.WhaleblubberisarichsourceofvitaminC,sothisfoodwouldhelppreventscurvy.
33. Inuitpeopleknewthatmaktaaqandmanyotherfoodsintheirtraditionaldietpromotedgoodhealth.Althoughthetermvitamin Cwasnotintroduceduntilthetwentiethcentury,thecollectiveexperiencesfromthousandsofyearsofinteractionwiththeArcticenvironmentallowedInuitpeopletodevelopanunderstandingofwhatfoodcombinationskeptpeoplehealthy.ThisinformationwouldhavebeenveryhelpfultotheearlyEuropeanArcticexplorers.Thesolutionforavoidingscurvywasathand,especiallysincemanyoftheseearlyEuropeanswerewhalersandvitaminC-richwhaleblubberwaslikelyalreadyaboardtheirships.
Practice, page 45
34. Thesandwichfillingcontainingpeanutbutterwouldbetheonlyonetobefreeofcholesterolbecausealltheotherfillingscomefromanimalsources.
35. a. Theunitmmol/Lmeansmillimolesperlitre,whichisaunitofconcentration.
b. PersonBhasthehealthiercholesterollevels.OnereasonforthisisthatthispersonhaslowerlevelsofLDLcholesterol.Low-densitylipoproteincarriescholesterolfromthelivertothebody’stissuecellsandintheprocesscanaddtotheunhealthyaccumulationofcholesterolontheinsideofarteries.
AnotherreasonisthatpersonBhashigherlevelsofHDLcholesterol.High-densitylipoproteinscoursthebloodstreamforcholesterolandthentransportsthecholesteroltothelivertoeliminateitfromthebody.HigherlevelsofHDLmeansthatmorecholesterolisbeingeliminatedfromthebody.
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Practice, page 46
36. Cardiovasculardiseasereferstoawiderangeofdisordersthataffecttheheartand/orbloodvessels.Examplesincludecoronaryheartdisease,strokes,andvaricoseveins.Atherosclerosisisanotherexample.Thisdiseaseinvolvesdepositsofcholesterolandotherfattysubstancesbuildingupontheinsideliningofanartery.Ifthearteryisacoronaryartery,thisdisordercanleadtocoronaryheartdiseaseandaheartattack.Ifthearteryisonethatsuppliesthebrainwithblood,thedisordercanleadtoastroke.
37. a. Plaquecandevelopaharderoutersurfacethatisrigidandinflexible.Sinceplaqueisattachedtotheinsideofanartery,thearterylosesitselasticity.
b. Astheleftventriclecontracts,bloodispushedthroughtheaortatotherestofthebody.Thesystolicbloodpressurethatresultspushesonthewallsofhealthyarteries,causingthemtoslightlyexpand.Whentheventriclesrelax,thehealthyarteriescontractslightlyastheyreturntotheirinitialshape.Theresidualpressurethatresultsisresponsibleforthediastolicpressure.
Arterieslinedwithcholesterolandplaqueareunabletoslightlyexpandandcontract.Thiswouldhavetheeffectofraisingthevaluesofthesystolicpressureand,therefore,theresidualdiastolicpressure.
38. Asplaquebuildsupontheinsideofarteries,theouterplaquesurfacecanbecomehardandrigidwitharoughsurface.Crackscandevelopintheplaque.Sinceplateletsrupturewhentheypassoveraroughsurface,thepresenceofplaquemakestheclottingprocessmorelikely.
Practice, page 49
39. Onlyabout25%ofcholesterolinthebloodstreamismadeupofcholesterolabsorbedfromfood.Reducingthecholesterolcontentoffoodeatencanonlyinfluenceone-quarterofthetotalcholesterolinaperson’sbloodstream.
40. a. Thebreakfastdescribedincludesbaconandbutter,whicharebothhighinsaturatedfat.Theegghassomesaturatedfat,butitisasignificantsourceofdietarycholesterol.Overall,thismealhasanegativeeffectonbloodcholesterollevels.ThesaturatedfatinthebaconandthebuttertendstoelevatethelevelsofLDLcholesterol.
b. Thedeep-friedonionringsandthedonutarelikelybothsourcesoftransfats.TransfatstendtoraisethelevelsofLDLcholesterolandlowerHDLcholesterollevels.Theoveralleffectisasignificantriseinbloodcholesterollevels.
Althoughthelargesoftdrinkdoesnotcontributetobloodcholesterollevels,itisasignificantsourceofsugar.TheexcessiveconsumptionoffoodsrichinsugarhasbeenlinkedtoobesityandalsototypeIIdiabetes.BothobesityandtypeIIdiabeteshavebeenshowntoincreasetheriskofheartattack.
c. Tunaisasourceofpolyunsaturatedomega-3fattyacids,whileoliveoilisasourceofmonounsaturatedomega-9fattyacids.BothofthesesubstancestendtolowerLDLcholesterollevelsandraiseHDLcholesterollevels,resultinginanoverallpositiveeffectonbloodcholesterollevels.Thismealisthehealthiestchoiceofthethreemealspresented.
41. Fatisanimportantnutrientneededtomakehealthycellmembranes,toproperlydevelopthebrainandnervoussystem,andtoproducehormone-likesubstancesthatregulatebodyfunctions(e.g.,bloodpressure).Adietthateliminatesallfoodscontainingfatisveryunhealthybecauseanessentialnutrientisdenied.
Iftheonlysourceoffatisanoccasionalbingeoffriesandgravy,thenthebodyisstilldeniedessentialfattyacidsbecausethissnackisrichinsaturatedfatsandtransfats,butnotomega-3andomega-6essentialfattyacids.Inaddition,thefriesandgravywillalsocauseanunhealthyspikeinbloodcholesterollevels.
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Practice, page 52
42. a. Theproblemaddressedbyhavingpeopleincreasethemarinesourcesofomega-3fattyacidsintheirdietsisthehighincidenceofcardiovasculardiseaseinthegeneralpopulation.CardiovasculardiseaseisthenumberonecauseofdeathinCanada.
b. Severalunintendedproblemsmightarisefromthistechnologicalsolution.Iflargenumbersofpeopleinthedevelopedworldbegantoeatfishasastaplepartoftheirdiet,therecouldbeanegativeeffectonboththemarineenvironmentandoceanecosystems.Theworld’soceansarealreadystressed,andawidespreadchangeineatinghabitscouldhaveanegativeeffectonfishstocks.
Anotherproblemisthatpeoplecouldgetthemessagethatalltheyhavetodoischangetheireatinghabits,attheexclusionoftheotherriskfactorsforcardiovasculardisease.Evenifeatinghabitschange,therewillbelittlechangeintheincidenceofcardiovasculardiseaseifpeoplecontinuetoliveinactivelifestyles.
c. Thedepletionoffishstockscouldbesolvedbyfindingotherwaysofaddingmarineomega-3fattyacidstopeople’sdiets.Perhapsanimalfeedcouldbesupplementedwithfishoiltoaugmenttheomega-3fattyacidcontentineggs,milk,andmeat.However,makingdramaticchangestowhatisfedtoanimalsisariskybusinessthatcanhaveunpredictableeffects—outbreaksofBovineSpongiformEncephalopathy(BSE)incattleareacaseinpoint.
Anothersolutionmightbetofindamarineplantthatcanproducethemarineomega-3fattyacidsratherthanalwaysrelyinguponfish.Themarineplantscouldbeharvestedandthenincorporatedintootherfoodproducts.Again,ifthisweretobedoneonalargescale,sustainabilityandenvironmentaleffectsontheoceanswouldhavetobeconsidered.Anotherpossibilitywouldbetogeneticallyengineerlandplantstoproducethemarineomega-3fattyacids.Again,thistechnologicalfixhasitsownrisks.
43. a. Thedefinitionfortraditionalecologicalknowledgeisasfollows.
Traditionalecologicalknowledgeisknowledgeacquiredoverthousandsofyearsthroughapeople’sdirectcontactwiththeenvironment.It’sadynamicapproachtodevelopingnewunderstandingsofhumaninteractionswiththeenvironmentthatfocusesontheinseparablerelationshipbetweenland,resources,andculture.
Thelastpartofthisdefinitionimpliesaholisticapproachthatgoesbeyondtheminutiaeofthedetailstoincludeconnectionsbetweenland,resources,andculture.
b. Abenefitofintegratingscientificresearchwithtraditionalecologicalknowledgeisthattwodifferentpointsofviewcanbeusedtosolveproblems.Thescientificpointofviewbringsmethods,tools,andtechnologiesofWesternscience,whiletraditionalecologicalknowledgebringsthousandsofyearsofhumanexperiencewiththeenvironment,aswellasaviewpointthatstressesconnectionstothewidercontextofcultureandotherhumandimensions.
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44. Thefollowingisasampleofhowyoumayhavecompletedthequestionnaire.
CardiovascularDiseaseRiskQuestionnaire
Readthefollowinglifestyleandfamilyhistorystatementsthatrelatetocirculatorydiseases.Placeacheckmarknexttotheonesthatapplytoyou.
❏✓ 1. Ihaveafatherorbrotherwhohadaheartattack,astroke,oraheartprocedure(e.g.,angioplasty,coronarybypass,oranotherexample)beforeage55.
❏ 2. Ihaveamotherorsisterwhohadaheartattack,astroke,oraheartprocedure(e.g.,angioplasty,coronarybypass,oranotherexample)beforeage65.
❏✓ 3. IsmokeorIamexposedtosecond-handsmoke.
❏ 4. Mybloodpressureisgreaterthan140/90mmHg.
❏ 5. Ihavediabetes.
❏✓ 6. Iamphysicallyinactiveandrarelyengageinaerobicexerciseactivities,suchascycling,jogging,swimming,andsoccer.
❏ 7. Iamunderhighstress.
❏✓ 8. Iam20ormorepoundsoverweight.
❏✓ 9. Mydietcontainsalotoffoodshighinsaturatedfats,transfats,andcholesterol,suchasredmeats,wholemilk,cream,butter,cheese,fastfoods,andfriedfoods.
1.4 Questions, page 54
Knowledge
1. a. angina b. stroke c. septaldefect d. atherosclerosis e. plaque f. heartattack g. aneurysm
applying Concepts
2. Thepatientwouldmostlikelybeaskedifshesmokesandeatsalotofhighsaturatedfatandhighcholesterolfoods.Shemaybeaskedhowmuchandwhatkindofexerciseshedoes,orifsheisunderalotofstress.Suggestionsforreducingtheriskofdevelopingacardiovasculardiseaseincludequittingsmoking,havingamorehealthydiet,andexercisingregularly.
3. a. Ifsomethingisstuckinoneofthepipesandcausessomehomestolosewaterservice,thissituationiscomparabletoabloodclotinthehumancirculatorysystem.
b. Ifthewaterpressureissohighthatastrainisputonthepipes,causingthepipestoleak,thesituationiscomparabletohighbloodpressureorhypertensioninthehumancirculatorysystem.
c. Afaultyvalveinthewaterpumpiscomparabletoaheartvalvedefectinthehumancirculatorysystem.
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4. Fataccountsfor0.74%oftheservingmassformoosemeat.Forbeef,22.55%oftheservingmassisfat.
5. Fatisaveryconcentratedformoffoodenergy.Thefactthatbeefisnearlyone-quartersaturatedfataccountsforitshigherenergycontent.
6. Saturatedfataccountsfor0.22%oftheservingmassformoosemeat.Forbeef,9.16%oftheservingissaturatedfat.
7. Duetoitslowsaturatedfatcontent,moosemeathasahealthiereffectonbloodcholesterollevelsthanbeefdoes.BeefhasagreatertendencytoraiseLDLcholesterollevelsduetoitshighsaturatedfatcontent.
8. Thefollowingcalculationsshowthepercentageoftotalfatthatisduetoomega-3andomega-6fattyacidsinmoosemeatandbeef.
MooseMeat
• omega-6fattyacid
m
mO
TF
g
g6
0 14
0 74
===
.
.
% ?
% %
.
.%
%
=ÊËÁ
ˆ¯̃
¥
= ÊËÁ
ˆ¯̃
¥
=
m
mO
TF
gg
6 100
0 140 74
100
19
Ofthetotalfatinmoosemeat,19%iscomposedofomega-6fattyacids.
• omega-3fattyacid
m
mO
TF
g
g3
0 03
0 74
===
.
.
% ?
% %
.
.%
. %
=ÊËÁ
ˆ¯̃
¥
= ÊËÁ
ˆ¯̃
¥
=
m
mO
TF
gg
3 100
0 030 74
100
4 1
Ofthetotalfatinmoosemeat,4.1%iscomposedofomega-3fattyacids.
Beef
• omega-6fattyacid
m
mO
TF
g
g6
0 57
22 55
===
.
.
% ?
% %
..
%
. %
=ÊËÁ
ˆ¯̃
¥
= ÊËÁ
ˆ¯̃
¥
=
m
mO
TF
gg
6 100
0 5722 55
100
2 5
Ofthetotalfatinbeef,2.5%iscomposedofomega-6fattyacids.
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• omega-3fattyacid
m
mO
TF
g
g3
0 23
22 55
===
.
.
% ?
% %
..
%
. %
=ÊËÁ
ˆ¯̃
¥
= ÊËÁ
ˆ¯̃
¥
=
m
mO
TF
gg
3 100
0 2322 55
100
1 0
Ofthetotalfatinbeef,1.0%iscomposedofomega-3fattyacids.
9. Themoosemeathasagreaterpercentageofomega-6andomega-3fattyacidsinitstotalfatcontent.ThismeansthatthemoosemeathasabetterchanceofraisingHDLcholesterollevelsandloweringLDLcholesterollevels.
10. MoosemeathaslesssaturatedfatthatwillraiseLDLlevelsandagreaterpercentageofitsfatconsistsofpolyunsaturatedfattyacidsthatwilllowerLDLlevelsandraiseHDLlevels.Overall,moosemeatisagoodchoiceforreducingriskfactorsassociatedwithcardiovasculardiseases.
Practice, page 57
45. Thefollowingtablecomparestherolesandpartsofacastlefortresstothepartsoftheimmunesystem.
Part of Immune system role Part of a Castle
skinprotective barrier that keeps
out invaderscastle walls
cilia and mucous secretionstrap invaders as they try
to enterguarded entrances and moat
plateletspatch holes in protective
barrierstonemasons
white blood cellsdestroy invaders who make it
past first line of defencedefensive army
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score scoring Description
standard of excellence (4 marks)
The response is well organized and addresses all the major points of the activity. Relevant scientific, technological, and/or societal concepts and examples are identified and interrelationships are explicit. The descriptions and/or explanations of these concepts are correct, well organized, and reflect thorough understanding and logical consistency of thought. The student uses complete sentences that make effective use of scientific vocabulary. When appropriate, suitable metaphors, similes, diagrams, and/or sketches are used to illustrate descriptions and/or explanations.
(3 marks)
The response is organized and addresses most of the major points of the activity. Relevant scientific, technological, and/or societal concepts and examples are identified and interrelationships are evident. The descriptions and/or explanations of these concepts are organized and reflect correct understanding. The student uses complete sentences that employ correct scientific vocabulary. When appropriate, suitable diagrams or sketches are used.
acceptable standard (2 marks)
The response addresses most major points. Relevant scientific, technological, and/or societal concepts and examples are identified, and interrelationships are shown. The descriptions and/or explanations of concepts may be disorganized but demonstrate correct understanding. The student uses complete sentences but is inconsistent in the use of appropriate scientific vocabulary, diagrams, and sketches.
(1 mark)
The response addresses few major points. Concepts are identified, but interrelationships are not evident. The student superficially describes concepts in sentences, but organizational skills, scientific vocabulary, diagrams, and sketches are minimal.
(0 marks)The response does not address any of the major points of the question at an appropriate level for a 30-level course.
rubrIC for KnoWLeDGe
Practice, page 62
46.
type of Pathogen Defining Characteristics example of a Disease Caused
by this type of Pathogen
protozoansmicroscopic, single-celled organisms with a nucleus—most can only divide within a host organism and cause disease
Malaria is caused by protozoans that infect red blood cells.
fungiorganisms that absorb food directly through cell walls and do not conduct photosynthesis
Athlete’s foot is a fungal infection.
bacteriamicroscopic, single-celled organisms that don’t have their genetic material contained in a nucleus
Salmonella bacteria cause food poisoning.
virusesextremely tiny particles consisting of a protein coat enclosing genetic material; viruses are not considered to be living organisms
Influenza is caused by a virus.
MICrosCoPIC PatHoGens
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47. Thereasonthatvirusescouldnotbeseenthroughalightmicroscopeorisolatedusingfiltersisthattheseparticlesareextremelysmall.Sincetheyareonlyabout1/100thesizeofabacterium,theyaredifficulttoobserve.
Practice, page 66
48. a.andb.
Theanswerstothesequestionscanbefoundontheillustrationlabelled,“OverviewofImmuneResponse”inthetextbook.
49. a.andb.
sketch of Components name of Components
role(s) in the Immune response
Antigenallow white blood cells to recognize foreign invaders
Macrophage
patrol and engulf foreign disease-causing organisms and display antigens on their cell membranes
Helper T-cellidentify antigens of foreign invaders and signal response of B-cells and killer T-cells
tHe IMMune resPonse—CoMPonents anD roLes
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B-cellproduce specific antibodies to antigens
Antibody attach to antigen of foreign material
Killer T-celldestroy cells that have become mutated or infected with viruses
Memory B-celland
Memory T-cell
remain after invading organism has been destroyed to allow for quicker response to future encounters with that antigen
Suppressor T-cell signal for immune response to end
Practice, page 67
50. Althoughmostofyouwillhaveaccesstoyourownvaccinationrecords,someofyoumaynothavereceivedvaccinationsduetoreligiousorotherreasons.
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Practice, page 69
51. AlthoughitwasverybeneficialtosocietyforJennertotestouthistheoryonahumansubject,JamesPhippscouldhavediedfromthesmallpoxvirus.ThiswasnotanethicalpracticesinceJamesPhippswasnotoldenoughtoconsenttothistreatment.
52. Thesepeoplewereparticularlysusceptibletothesmallpoxvirusbecausetheyhadneverbeenexposedtothisdisease-causingorganism,sonoonehadmemorycellstomakeantigens(naturalimmunity)againstsmallpox.Thismeansthattheviruscouldspreadveryquicklythroughthepopulation.
53. a. Themajorconcernwithkeepingtheviralstockisthatsincenoonegetsvaccinatedanymore—duetothedangerofhandlingthevirusandthedangerous(evenfatal)sideeffectsofthevaccination—areleasedviruswouldcausemajorsicknessinanunvaccinatedpopulation.Somepeopleworrythattheviruscouldevenbeusedasabioterrorismweaponifitwaspurposelyreleasedintoapopulation.
b. Keepingthesestocksisbeneficialbecausetherearespecimenstostudyandtoproduceavaccinefrom.Ifavirusisreleasedinabioterrorismact,thenalaboratorysampleofthesmallpoxvirusisavailabletobeexamined.
1.5 Questions, page 70
Knowledge
1. a. Malariaisavector-bornediseasethatgetsintothebodyviaamosquitothatpuncturestheskinbarrier.Malarialivesinsideredbloodcells,whichmakesitdifficultforwhitebloodcellstodetectitasaforeigninvader.
b. HepatitisCisablood-bornediseasethatisusuallytransmittedthroughtheskinbarrierthroughthesharingofneedlesorbysexualintercourse.
c. Tuberculosisisanairbornediseasecausedbyinhalingdropletsfromaninfectedperson’slungs.
d. Salmonellaisafood-bornediseasethatcomesfromeatingimproperlycookedfoodorfoodcontaminatedbyfeces.Stomachacidisunabletokillalltheinvadingorganisms.
2. Althoughautoimmunediseasesandinfectiousdiseasescanbothmakeyousick,anautoimmunediseasecannotbecaughtbecauseitdoesnotcomefromaninvadingpathogenasdoesaninfectiousdisease.Anautoimmunediseaseoccurswhenaperson’swhitebloodcellstargetandattacksomeorallofthebody’scells.Autoimmunediseasescannotusuallybecured,sothisconditionoftenlastsfortheremainderofaperson’slife.
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3. Atablefollowscomparingthesimilaritiesanddifferencesbetweenbacteriaandviruses.
similarities Differences
Both cause sickness. Bacteria can be treated by antibiotics.
Both are too small to see with the naked eye. Viruses are much smaller than bacteria.
Both must break through the body’s first line of defenses (e.g., skin, mucus) to make you sick.
Viruses are considered non-living.
You can be vaccinated against both types of pathogens.
Bacteria reproduce by splitting in two.
Both come in a variety of shapes.Some bacteria can be harmless or even beneficial, while all viruses cause disease.
4. Youcancheckyourworkbyreplayingtheappletandcomparingtheinformationpresentedwiththeinformationpresentedinthetextbook.OneminordiscrepancyisthatthevideoshowsthekillerT-cellactuallyattackingthemembraneoftheinvadingpathogen—thecurrentunderstandingisthatkillerT-cellsdestroytissuecellsthathavetheantigensofthepathogenontheircellmembranes.
applying Concepts
5. a. Ifapersonwithhemophiliahasbloodthatdoesnotclotproperly,cutsorbreaksintheskinwillberepairedandpluggedmoreslowly.Thisdelayinrepairingtheskinincreasesthechancesfordisease-causingorganismstocrosstheskinbarrier.
b. Withouttheskinbarrier,bodytissueswillbeexposedtodisease-causingpathogensthatcanmoreeasilyenterthebloodstream.
c. IfsomeonewithHIVhasT-cellsdestroyedbythevirus,thendiseasesthatenterthebodycanonlybeeatenbythemacrophages.Therewillbenodirectedattackwithspecificantibodiestotargettheseinvaders.Unfortunately,peoplewithHIVcandiefromdiseasesandrarecancersthatthebodycouldnormallydealwithifT-cellswerepresent.
6. a. Whenvaccinationsaregivenatbirth,memorycellsareproducedsothatfuturediseaseencountersareeasilydealtwith.
b. Ifantibioticsareprescribedwhenyouhaveaninfection,bacteriagrowthisinhibited.
c. Antisepticsusedduringoperationsdestroymostdisease-causingagentsthathavegoneintoawoundorincision.
7. Role-playinganimmuneresponseisanexcellentwaytohaveparticipantsperformself-assessment.Teachersmaywanttodeveloporuseaperformance/presentationrubricorhavestudentshandintheirscriptsforreview.
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