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Adding pieces to the puzzle of endometriosis Scientific Programme 30 April - 3 May 2014

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Page 1: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Adding pieces to the puzzle of endometriosis

Scientific Programme

30 April - 3 May 2014

Page 2: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome
Page 3: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.00 to 18.30Contents

Sponsors

Welcome

Partner organisations

WES and committees

Venue plan

At a glance programme

Pre-congress courses Wednesday

Opening ceremony

Programme Thursday

Programme Friday

Programme Saturday

Closing ceremony

Exhibitor / poster floor plan

Sponsor profiles

List of presenters

Local information

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Page 4: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

The organisers of WCE2014 would like to thank our generous sponsors

Diamond

Gold

Ruby

Silver

Bronze

Supported by

4

Page 5: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Dear Colleagues and Friends,

Welcome to São Paulo and to the 12th World Congress on Endometriosis.

The theme of WCE2014, “Adding pieces to the puzzle of endometriosis”, has been chosen because we

are currently experiencing a rapid advancement of new technologies for the diagnosis and management

of endometriosis and, with that, improvements in our understanding of the disease.

At the heart of every congress is the scientific programme, which keeps the momentum of our advancements in endometriosis

alive through a robust exchange of ideas among the experts and learners in the field. We have received more than 500 outstanding

abstracts from the international community, and have put together an extensive and in-depth programme featuring more than 150

speakers and close to 300 poster presentations spanning almost every topic you can imagine that has relevance to endometriosis.

This is truly the world event on endometriosis and I welcome each and every one of you to São Paulo to be part of this clinical and

scientific extravaganza!

For me it is an exciting time to welcome you to São Paulo, one of the top international capitals for gastronomy, architecture and design,

cultural heritage and music. You will find São Paulo home to remarkable museums and concert halls, memorable restaurants, and unique

bars. Do explore the neighborhoods where you will come upon noteworthy cafes, boutiques, and vibrant streets. As the capital of a state

that generates almost half of the Brazilian economy, São Paulo has many reasons for being the first tourist destination in this country.

The Local Organising Committee hopes that you will find time to explore the many cultural opportunities the city has to offer, in between

adding the necessary puzzles to the jigsaw that is endometriosis, so that collectively we can keep the momentum going and continue to

move our field forward for the benefit of millions of women around the world.

Enjoy the Congress and our lively city!

Mauricio Abrao

WCE2014 President

Welcome

5

Maurício Simões Abrão, WCE2014 President

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Welcome

SÃO PAULO 2014: ENDOMETRIOSIS BETWEEN SCIENCE AND PASSION

Welcome to the first attendee-centered meeting on endometriosis. In this era of patient-centered medicine,

when the preferences of our patients are crucial for medical decision-making, we thought it was opportune

to adopt a similar approach for the World Congress on Endometriosis, including the topics that matter to

you. This is why the scientific programme has been shaped respecting the results of an online survey in

which you expressed your preferences regarding the issues to be addressed. Moreover, in a scientific

environment characterised by an overwhelming amount of industry-sponsored studies, we continue to foster independent research.

Since 2005 in Maastricht, the vast majority of presentations for our trienniel meeting are selected from the abstracts that you submitted.

On this occasion, we will commemorate Maurice Bruhat, one of the greatest pioneers of modern gynaecology, who left us a few

weeks ago. It was Bruhat who organised the first World Congress on Endometriosis in 1986 in Clermont-Ferrand. We are all

indebted to him, and Michel Canis will dedicate a tribute to this visionary clinician and scientist.

This year we have the special honor of hosting Fiona Godlee, the Editor-in-Chief of the British Medical Journal, who will present

a lecture on overdiagnosis and overtreatment. The Scientific Committee felt that the introduction of a general medical topic of such

importance would benefit also those interested in our specific research area. It is a unique opportunity for us, and you will certainly

appreciate her enlightening thoughts.

Indeed, the paradigms of medicine apply also to the research and management of endometriosis. In 1894 the University of Vienna

commissioned three paintings from Gustav Klimt to celebrate the faculties of Philosophy, Medicine, and Law, reflecting the general theme

of “the triumph of light over darkness”. Medicine was completed in 1901 and provoked a big scandal, as the painting reaffirms that the

connection between life and death is inevitable. Drifting bodies of men and women of different ages, a pregnant woman, a child, are

shown to symbolise the course and flow of life. A skeleton is also featured, to emphasise the antithesis of life, the failure of health.

On the right side of the canvas a floating body of a naked young woman is represented. She appears unconscious, helpless,

beyond the connections with reality and the rest of humanity.

“At the forefront of the canvas stands Hygeia, beautiful and ignorant of the despairing

humanity; she has the power of healing but she keeps it to herself – it is what keeps her

apart from the rest; without her gift, she would be one of them; she guards it like a priestess

guards an oracle; she holds the knowledge of life and death and the antidote to pain but

she does not offer it to the people” The painting has been interpreted as an attack to

physicians, at whose mercy is all of humanity. “Klimt seems to be presenting them as

sorcerers rather than scientists; medicine is but a spell incapable of salvation. People

are born to die – what can medicine promise to break that cycle?”

(http://suitesculturelles.wordpress.com/2011/08/24/vienna-secession-klimt-freud-and-jung/).

6

Paulo Vercellini, President World Endometriosis Society

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Welcome

7

Paulo Vercellini President World Endometriosis Society

In 1899 Gustav Klimt painted another masterpiece that seems relevant to our meeting, “Nuda Veritas”.

A naked young woman shows herself hiding nothing but without provocative postures. She is pale, with

red hair, a petrified look, disquieting. The woman holds a mirror facing the viewer. The woman embodies

“The Truth”, undermined by lies, symbolised by the snake at her feet. Facing the mirror toward us, she

admonishes us to avoid mendacity and deception and to search for the truth, whatever risks, efforts, and

troubles this might take.

We are here in São Paulo to accept the challenge that Gustav Klimt directed to physicians with his

Medicine more than a century ago. We are here to reaffirm that our patients are central to our thinking

and acting, and that everything we do is done in their interest, not in our interest. We do not always have

the power of healing, but we convene, in this meeting, to look for the best available modalities to relieve

suffering. And we will always strive in the search of truth. The woman depicted in Nuda Veritas has the

typical phenotypic traits of a patient with endometriosis: pale, sun-sensitive skin, red hair, low body-mass

index. She severely asks for truth: let us confront with an open mind and free thinking, and let us look in

her mirror without fear. The 12th World Congress on Endometriosis can begin.

Paulo Vercellini, President World Endometriosis Society

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Partner organisations

WCE2014 acknowledges the support of the following organisations in support and promotion of this congress.

Romanian

Society of Obstetrics and

Gynecology

8

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WES and committees

9

World Endometriosis Society

The world congresses on endometriosis extend back to 1986, when Professor Maurice

Bruhat gathered clinicians and scientists, who had a specific interest in endometriosis, for

what became the 1st World Congress on Endometriosis held in Clermont-Ferrand, France.

More than a decade later, at the 6th World Congress on Endometriosis in Quebec in 1998,

Rodolphe Maheux and Jacques Donnez founded the World Endometriosis Society (WES).

As a non-profit organisation, WES promotes and facilitates the exchange of clinical and

scientific experience, thought, and investigation. WES has succeeded in meeting these

goals by:

• gathering thousands of experts at our world congresses for “downright good

discussions” at global meetings to add pieces to the puzzle that is endometriosis;

• supporting two workshops where researchers have brainstormed on research

priorities in endometriosis, resulting in two publications and the acknowledgment

of endometriosis as a research priority (the third workshop is on 4 May 2014!);

• developing the first film on “Endometriosis: symptoms, treatment, and diagnosis”

in five languages;

• organising the first global consensus in the current management of endometriosis

(published in Human Reproduction in 2013);

• continuously publishing opinions and news via our eJournal – sparking that

all important exchange of experience;

• participating in numerous national and regional meetings on endometriosis;

• supporting and contributing to the World Endometriosis Research Foundation

(WERF) in its mission to provide a global platform for researchers to collaborate

on its quest to determine the phenotype of endometriosis and consequently develop

targeted treatments.

Local Organising Committee

WCE2014 President

Mauricio Simoes ABRÃO

WCE2014 Vice President

Carlos Alberto PETTA

Scientific Programme Chair

Rui Alberto FERRIANI

Treasurer

Sergio PODGAEC

Secretary

Eduardo SCHOR

1st Secretary

Claudio CRISPI

Pre-congress Programme Chair

Luis Flavio FERNANDES

Social Programme Chair

Nicolau D’AMICO

International Scientific Committee

Hilary CRITCHLEY, United Kingdom

Johannes EVERS, The Netherlands

Emilio FERNANDEZ, Chile

Linda GIUDICE, USA

Sun-Wei GUO, China

Bernard HÉDON, France

Lone HUMMELSHOJ, United Kingdom

Neil JOHNSON, New Zealand

Ludwig KIESEL, Germany

Alan LAM, Australia

Joao Sabino Cunha NETO, Brazil

Marco Aurelio PINHO DE OLIVEIRA, Brazil

Paulo Ayroza Galvão RIBEIRO, Brazil

Rishma PAI, India

Edgardo ROLLA, Argentina

Luk ROMBAUTS, Australia

Kathy SHARPE-TIMMS, USA

Robert TAYLOR, USA

Paolo VERCELLINI, Italy

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Venue plan

10

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endometriosis.orgglobal forum for news and information

Endometriosis.org is the global platform linking all stake

holders in endometriosis − one of the most common causes of

pelvic pain and infertility in women.

We facilitate collaboration and information sharing between

women with endometriosis, physicians, scientists, and others

interested in the disease. �is international cooperation and

exchange of experience enables us to deliver up to date,

evidence based, information and news about endometriosis.

Our goal is to empower women with endometriosis to

participate fully in making informed decisions about their

treatment options.

monthly news · updates in research advancements · treatment options · guidelines · coping articles

clinical trials · global support groups · bookstore · congress schedule · www.endometriosis.org

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16.00 to 18.30Wednesday 30 April 2014

14

Roberto Blasbalg (BR)

Relevance of imaging exams in the treatment planning of patients with endometriosisMichel Canis (FR)

Protocols: Ultrasound and Magnetic ResonanceLeandro Accardo de Mattos (BR)

Ultrasound and MRI in endometriomas. When suspecting malignancy?Ana Luisa Alencar De Nicola (BR) and Roberto Blasbalg (BR)

DISCUSSION

Coffee break

Vivian Amaral (BR)

Correlation of MRI with surgical findings: intestinal and retrocervical sitesAlice Brandão (BR)

Ultrasound with bowel prepar: intestinal and retrocervical sites Manoel Orlando Gonçalves (BR)

MRI of bladder and ureter: relevance of parametrium Alice Brandão (BR)

DISCUSSION

LUNCH (not included in the price of the course)

Kleber Chagas (BR)

MRI and US of pelvic floor and atypical sites Leandro Accardo de Mattos (BR)

What is the main imaging exam to use for the staging of endometriosis? Eduardo Schor (BR) and Sergio Podgaec (BR)

Ultrasound mapping of pelvic endometriosis: does the location and number of lesions affect the diagnostic accuracy? Tom Holland (UK)

DISCUSSION

Coffee break

Sergio Podgaec

Training and learning curve on specialized protocols Scott Young (US)

MRI and US in tipical and atypical adenomyosis Roberto Blasbalg (BR)

Live ultrasound with questions from the audience Manoel Orlando Gonçalves (BR)

This course is organised by:

Endometriosis anatomy and pathophysiologyIgor Padovesi Mota (BR)

An overview of current medical and surgical interventionsLydia Myung (BR)

Assessing quality of life and psycho-social factors in women with endometriosisJamir Sardá (BR)

DISCUSSION

Pre-operative work-up – how can nurses be involved?Ana Paula Klautau (BR)

The role of physical therapy for post-op and for long-term pain managementSallie Sarrell (US)

Self-help programmesMaria Eugenia Albuquerque (BR)

DISCUSSION

This course is organised by

WCE2014 Pre-congress Course #1:Update on diagnostic imaging of endometriosis

Wednesday 30 April 2014 08.30 – 17.00

CHAIRS | Manoel Orlando Gonçalves(BR), Alice Brandão (BR), and Scott Young (US)

WCE2014 Pre-congress Course #2:The role of nurses and allied health professionals in caring for women with endometriosis

Wednesday 30 April 2014 14.00 – 17.00

CHAIRS | Vibeke Amelung RN (DK) and Mariana Matzenbacker RN (BR)

Coordinator: 14.00 – 14.15

08.30 – 09.0014.15 – 14.30

09.00 – 09.30 14.30 – 15.00

09.30 – 10.00

15.00 – 15.30

10.15 – 10.45

10.00 – 10.15 15.30 – 15.45

Coordinator: 15.30 – 15.45

10.45 – 11.15 16.15 – 16.30

16.30 – 17.00 11.15 – 11.45

11.45 – 12.15

12.15 – 12.30

12.30 – 14.00

Coordinator:

14.00 – 14.20

14.20 -14.40

14.40 – 15.00

15.00 – 15.15

15.15 – 15.40

Coordinator:

15.40 – 16.00

16.00 – 16.20

16.20 – 17.00

BALL ROOM 1

BALL ROOM 4

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16.00 to 18.30Wednesday 30 April 2014

15

Role of surgery in the treatment of endometriosisMauricio Abrao (BR)

Retroperitoneal anatomy of female pelvis: what we need to know for a safe surgery for endometriosis?Paulo Ayroza Galvão Ribeiro (BR)

Endometriosis of the anterior compartment: vesical and ureteral endometriosis. Surgical anatomy and laparoscopic approach.Mario Malzoni (IT)

Endometriosis of the posterior compartment: Pouch of Douglas, recto-vaginal septum, utero-sacral ligaments. Surgical anatomy and laparoscopic approach.Jörg Keckstein (AT)

BREAK

Endometriosis of the rectum and lateral compartments: nerve-sparing rectal and parametrial resection for deep infiltrating endometriosis. Surgical anatomy and laparoscopic approach.Marcello Ceccaroni (IT)

Endometriosis of uncommon sites (diaphragm, pericardium, pleura, groin). Surgical anatomy and laparoscopic approachRoberto Clarizia (IT)

Endometriosis of the somatic nerves and pelvic wall. Surgical anatomy and laparoscopic approach. Marcello Ceccaroni (IT)

Q&A and DISCUSSION

Surgical management of ovarian endometriosis and fertility considerations Marco Aurelio Oliveira (BR)

Understanding principles in the use of energy in laparoscopic/robotic excision of endometriosis Armando Romeo (BR)

Avoiding complications through mastery of anatomy Carlo De Cicco (IT)

Q&A and DISCUSSION

LUNCH (not included in the price of the course)

Surgical management of adenomyosis Jörg Keckstein (AT)

New Technology in Surgery: 3D imaging in Laparoscopy Kevin Stepp (US)

Microlaparoscopy for endometriosis treatment Mario Malzoni (IT)

The future of robotic surgery for endometriosis Arnold Advincula (US)

Current use of laser for endometriosis treatment Rosanne Kho (US)

BREAK

Video festival from the faculty

Q&A and DISCUSSION

Pelvic pain and non ovarian endometriosisP Santulli (FR)

Importance and modalities of imaging work-upLF Fernandes (BR)

Non ovarian localizations of endometriosis: symptoms and health impactS Singh (CA)

Which relationship between adenomyosis and deep endometriosis?C Chapron (FR)

COFFEE BREAK

Medical treatments for non ovarian endometriosis: are they specific? F Petraglia (IT)

Surgery for non ovarian endometriosisF Carmona (ES)

Impact of non ovarian endometriosis on infertilityC Petta (BR)

Management of infertility in deep endometriosis A Popov (RU)

This course is organised by

WCE2014 Pre-congress Course #3:Anatomy, energy, and new technologies for the surgical management of endometriosis

Wednesday 30 April 2014 08.30 – 17.00 CHAIRS | Manoel Orlando Gonçalves(BR), Alice Brandão (BR), and Scott Young (US)

WCE2014 Pre-congress Course #4:Non-ovarian endometriosis

Wednesday 30 April 2014 14.00 – 17.00 PRESIDENT | Felice Petraglia (IT)CHAIRS | Carlos Petta (BR) and Charles Chapron (FR)

08.30 – 08.50 14.00 – 14.20

08.50 – 09.10 14.20 – 14.40

08.50 – 09.1014.40 – 15.00

09.10 – 09.30

15.00 – 15.20

15.20 – 15.40

09.50 – 10.10

15.40 – 16.00

10.10 – 10.30 16.00 – 16.20

10.30 – 10.50

16.20 – 16.40

10.50 – 11.10

16.40 – 17.00

11.10 – 11.30

11.30 – 11.50

11.50 – 12.10

12.10 – 12.30

12.30 – 12.45

12.45 – 13.50

13.50 – 14.10

14.10 – 14.30

14.30 – 14.50

14.50 – 15.10

15.10 – 15.30

15.30 – 15.50

15.50 – 16.40

16.40 – 17.00

BALL ROOM 2

BALL ROOM 3

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16.00 to 18.30Wednesday 30 April 2014

16

Key mechanisms regulating endometriosis Ludwig Kiesel (DE)

Retroperitoneal anatomy of female pelvis: what we need to know for a safe surgery for endometriosis?Ludwig Kiesel (DE)

Anti-Apoptotic HMGA 2 Protein is a Key Molecule in the Pathogenesis and Development of Endometriosis Wolfgang Kuepker (DE)

Is adenomyosis an indication or contraindication for subtotal hysterectomy? Harald Krentel (DE)

Impact of surgical and hormonal therapy on endometriosisLiselotte Mettler (DE) and Ibrahim Alkatout (DE)

Risk factors for urogenital endometriosisMichel Müller (CH)

COFFEE BREAK

Pre- and postmenopausal factors influencing postmenopausal health Dietmar Haas (CH)

Influence of endometriosis on COH and oocyte quality in an ART cycle Omar Shebl (CH)

Pregnancy specific features in endometriosis Stefan Renner (DE)

Delivery after operation for deep infiltration endometriosis Peter Oppelt (CH)

Cell surface receptors as targets in endometriosis Martin Goette (DE)

DISCUSSION

This course is organised by

Sponsored by

Mild endometriosis and infertility: is there a link? Paula Navarro (BR)

Discussion

Adenomyosis and infertilityVivian Ferreira do Amaral (BR)

Discussion

Advanced endometriosis: Surgery or IVF? Dominique DeZiegler (FR)

Discussion

Appropriate ovarian stimulation for endometriosis patients Joao Antonio Dias Junior (BR)

Discussion

Treatment of poor responders and recurrent implantation failureRui Ferriani (BR)

Discussion

Tips and tricks for IVF laboratory in endometriosisCarlos Alberto Petta (BR)

Discussion

Clinical application of biomarkers of ovarian reserveJoao Sabino Neto (BR)

Discussion

Current status of cryopreservation before treating advanced endometriosis David Adamson (US)

Discussion

WCE2014 Pre-congress Course #5:Light into the myth of endometriosis

Wednesday 30 April 2014 10.30 – 13.30

CHAIRS | Liselotte Mettler (DE) and Ludwig Kiesel (DE) and Sylvia Mechsner (DE)

WCE2014 Pre-congress Course #6:Treatment considerations for infertility and endometriosis

Wednesday 30 April 2014 09.30 – 13.30

CHAIRS | Rui Ferriani (BR) and Carlos Petta (BR) 10.30 – 10.45 09.30 – 09.50

08.50 – 09.10

10.45 – 11.00

09.50 – 10.10

11.00 – 11.1509.10 – 09.30

11.15 – 11.30 10.40 – 11.00

11.30 – 11.45

11.30 – 11.45

11.05 – 11.30

11.30 – 11.50

12.00 – 12.15

11.55 – 12.15 12.30 – 12.45

12.30 – 12.4510.50 – 11.10

12.45 – 13.00 11.10 – 11.30

11.30 – 11.50

11.50 – 12.10

13.00 – 13.15

13.15 – 13.30

BALL ROOM 3

BALL ROOM 4

Page 17: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

GY

N 6

3 02

/201

4/A

-E

Better VisionLoop Excision Under Magnification with the VITOM® System

KARL STORZ GmbH & Co. KG, Mittelstraße 8, 78532 Tuttlingen/Germany, Phone: +49 (0)7461 708-0, Fax: +49 (0)7461 708-105, E-Mail: [email protected] KARL STORZ Endoscopy America, Inc, 2151 E. Grand Avenue, El Segundo, CA 90245-5017, USA, Phone: +1 424 218-8100, Fax: +1 800 321-1304, E-Mail: [email protected]

KARL STORZ Endoscopia Latino-America, 815 N. W. 57 Av., Suite No. 480, Miami, FL 33126-2042, USA, Phone: +1 305 262-8980, Fax: +1 305 262-89 86, E-Mail: [email protected] KARL STORZ Endoscopy Canada Ltd., 7171 Millcreek Drive, Mississauga, ON L5N 3R3, Canada, Phone: +1 905 816-4500, Fax: +1 905 858-4599, E-Mail: [email protected]

www.karlstorz.com

Page 18: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

GESTINOL 28® Gestodeno 75 mcg + Etinilestradiol 30 mcg contendo uma cartela ou três cartelas com 28 comprimidos revestidos. Uso oral e adulto. Indicações: contracepção contínua. Contraindicações: TVP (trombose venosa profunda), tromboembolismo (TE), doença cerebrovascular (DCV) ou arterial coronariana, fibrilação atrial, valvulopatias trombogênicas, distúrbios trombogênicos, hipertensão não controlada, distúrbios graves da função hepática, doença hepática ativa, história prévia ou atual de tumores hepáticos, diabetes com alterações vasculares, tumores hormônio-dependentes (útero/mama), sangramento vaginal não diagnosticado, tabagismo, gravidez confirmada ou suspeita e hipersensibilidade a qualquer componente do medicamento. Precauções e advertências: hipertrigliceridemia persistente, intolerância à glicose ou diabetes mellitus, depressão, “spotting”. Enxaqueca não habitual, perturbações visuais ou auditivas, tromboflebite, tromboembolia; angina, cirurgias eletivas, imobilização forçada, icterícia, hepatite, prurido generalizado, hipertensão e gravidez. Derrame cerebral ou IM; TE e trombose venosa ou arterial; proptose, diplopia, papiledema, lesões vasculares retinianas; hipertensão arterial, neoplasia cervical intraepitelial, câncer de mamas, neoplasia ou doença hepática, AVC, tabagismo.Gravidez e lactação: Categoria de risco X. Não é recomendado o uso de contraceptivos orais combinados (COC) até que a lactante tenha interrompido a amamentação. Este medicamento não deve ser utilizado por mulheres grávidas ou que possam ficar grávidas durante o tratamento. Interações com medicamentos, alimentos e álcool: fenitoínas, barbitúricos, primidona, carbamazepina, rifampicina, oxcarbazepina, topiramato, felbamato, ritonavir, griseofulvina, produtos contendo hipérico, certos antibióticos (penicilinas e tetraciclinas), atorvastatina, ácido ascórbico, paracetamol, inibidores do citocromo P450 (indinavir, fluconazol e troleandomicina), ciclosporina, teofilina, corticosteroides, lamotrigina, glucocorticoides, flunarizina, anticoagulantes, antidepressivos tricíclicos, diazepam, clorodiazepóxido. Reações Adversas e alterações de exames laboratoriais: cefaleia, enxaqueca e “spotting”; vaginite, candidíase, alterações de humor, depressão, alteração de libido, nervosismo, tontura, náuseas, vômitos, dor abdominal, acne, reações nas mamas, dismenorreia, alteração da secreção e ectrópio cervical, edema, alterações do peso e de apetite. Cólicas abdominais, distensão, erupções cutâneas, cloasma, hipertensão arterial, alterações séricas de lipídeos, hipertrigliceridemia; IC, AVC, TV e embolia pulmonar; neoplasia cervical intraepitelial e câncer cervical, câncer de mama, distúrbios gástricos, alterações da libido. Amenorreia pós-pílula ou oligomenorreia; fechamento da epífise em adolescentes. Posologia: iniciar no 1º dia da menstruação. Um comprimido ao dia, sempre no mesmo horário. Iniciar a cartela seguinte após o término da anterior e manter o tratamento de forma ininterrupta, e a pausa a critério médico. Usando pela primeira vez: iniciar a tomada no 1° dia do ciclo natural. No lugar de outro contraceptivo oral: tomar GESTINOL 28® de preferência no dia seguinte ao último comprimido ativo do COC anterior ter sido ingerido ou, no máximo, no dia seguinte ao intervalo habitual sem comprimido ou com comprimido inerte do COC anterior. No lugar de outro método com apenas progestagênio: pode parar a minipílula em qualquer dia e começar GESTINOL 28® no dia seguinte. Tomar GESTINOL 28® no dia da remoção do implante ou, no caso de utilização de contraceptivo injetável, esperar o dia programado para a próxima injeção. Em todas essas situações, a paciente deve utilizar outro método não hormonal de contracepção durante os sete primeiros dias de administração dos comprimidos. Após aborto no primeiro trimestre: pode tomar GESTINOL 28® imediatamente, não são necessários outros métodos contraceptivos. Após parto ou aborto no segundo trimestre: o tratamento com COCs deve começar 3-6 semanas após o parto em mães não lactantes ou após aborto no segundo trimestre. A paciente deve utilizar método não hormonal de contracepção durante os sete primeiros dias de administração dos comprimidos. Esquecimento: se menor que 12 horas, tomar GESTINOL 28® assim que se lembrar e o restante dos comprimidos no horário habitual. Maior que 12 horas ou mais, tomar o comprimido esquecido tão logo se lembre, mesmo que isso signifique tomar dois comprimidos num único dia e os comprimidos seguintes no horário habitual. Usar métodos contraceptivos de barreira por sete dias. Na ocorrência de vômitos ou diarreia dentro de 3-4 horas após a ingestão de GESTINOL 28®, continuar o tratamento para evitar sangramento prematuro de privação e usar método contraceptivo não hormonal até o final do ciclo. Reg. MS 1.0033.0027/Farm. resp: Cintia Delphino de Andrade - CRF-SP nº 25.125. LIBBS FARMACÊUTICA LTDA/CNPJ 61.230.314/0001-75/Rua Alberto Correia Francfort, 88/Embu das Artes-SP/Indústria brasileira/GESTINOL-MB01-12/Serviço de Atendimento Libbs: 08000-135044. VENDA SOB PRESCRIÇÃO MÉDICA. A persistirem os sintomas, o médico deve ser consultado. Documentação científica e informações adicionais estão à disposição da classe médica, mediante solicitação.

Contraindicação: trombose venosa profundaInterações medicamentosas: antibióticos (penicilina e tetraciclina)

Referência Bibliográfica: 1. GESTINOL 28®. São Paulo: Libbs Farmacêutica Ltda. Bula do medicamento.

EXISTEM DUAS MANEIRAS DE PROTEGERO QUE AS SUAS PAC IENTES TÊM DE MAIS PREC IOSO:

ISOLANDO, ESCONDENDO E APAGANDO SEU BRILHO.

OU ASSOCIANDO EFICÁCIA1 COM A FEMINILIDADE DA MULHER.

Page 19: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

C

M

Y

CM

MY

CY

CMY

K

Anuncio_Sonicision_21x14cm.pdf 1 3/7/14 12:57 PM

Opening ceremony

CHAIRS | Mauricio Abrao (BR) and Paolo Vercellini (IT)

19.00

19.05

19.25

20.00

Welcome to the 12th World Congress on Endometriosis Paolo Vercellini (IT)

KEY NOTE: Over-diagnosis, over-treatment, and responsible management of finite healthcare resources Fiona Godlee (UK)

Welcome reception

Welcome to Sao Paulo and WCE2014 Mauricio Abrao (BR)

Maurice Bruhat in memoriam Michel Canis (FR)

19.15

Sponsored by 19

Page 20: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

17 Thur

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Page 21: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Imm

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e se

rved

Spon

sore

d by

Chai

rs |

Carlo

s Pe

tta (B

R) a

nd A

lexa

ndr P

opov

(RU)

21

Page 22: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

19 Thur

sday

1 M

ay 2

014

15.

30 -

18.

30

16.0

0 –

16.1

2

16.1

2 –

16.2

4

16.2

4 –

16.3

6

16.3

6 –

16.4

8

Surg

ical

The

rapy

Chai

rs |

Sony

Sin

gh (C

A) a

nd A

lan

Lam

(AU)

Infe

rtili

ty a

nd A

RTCh

airs

| Ed

gard

o Ro

lla (A

R) a

nd N

icol

au D

’Am

ico

(BR)

Path

ogen

esis

/ ae

tiolo

gyCh

airs

| Asg

i Faz

leaba

s (U

S) a

nd M

oham

ed B

edaiw

y (CA

)Vi

deo

Sess

ion

1Ch

airs

| Pe

ter M

aher

(AU)

and

Lis

elot

te M

ettle

r (DE

)

S1-2

Early

rise

in s

erum

C-r

eact

ive

prot

ein

indi

cate

s su

bseq

uent

sur

gica

l com

plic

atio

n af

ter l

ow a

nter

ior r

esec

tion

for r

ecto

-sig

moi

d en

dom

etrio

sis

Mad

s Ri

iskj

ear (

DE)

S1-1

Co

lore

ctal

rese

ctio

n ve

rsus

rect

al

cons

erva

tive

surg

ery

in th

e m

anag

emen

t of

rect

al e

ndom

etrio

sis:

pre

limin

ary

resu

lts

of E

NDOR

E ra

ndom

ized

tria

l

Hora

ce R

oman

(FR)

S2-1

In

vitr

o fe

rtili

satio

n (IV

F)

embr

yo im

plan

tatio

n is

not

impa

ired

by

end

omet

riosi

s

Jean

Luc

Pou

ly (F

R)

S1-3

Surg

ical

man

agem

ent o

f end

omet

riom

as

on in

vitr

o fe

rtili

zatio

n ou

tcom

es:

A sy

stem

atic

revi

ew a

nd m

eta-

anal

ysis

Clar

a W

u (C

A)

S1-4

Nerv

e-sp

arin

g la

paro

scop

ic e

radi

catio

n

of d

eep

endo

met

riosi

s w

ith s

egm

enta

l re

ctal

and

par

amet

rial r

esec

tion:

Th

e ne

gar m

etho

d. A

pro

spec

tive

Mar

cello

Cec

caro

ni (I

T)

S2-2

Effe

ct o

f ind

uced

per

itone

al

endo

met

riosi

s on

ooc

yte

and

embr

yo

qual

ity in

a m

ouse

mod

el

Jona

than

Coh

en (F

R)

S2-3

Exte

rnal

val

idat

ion

of th

e en

dom

etrio

sis

fe

rtili

ty in

dex

in a

Fre

nch

popu

latio

n.

Tow

ards

indi

vidu

aliz

ed m

anag

emen

t of

infe

rtile

end

omet

riotic

not

yet

acc

epte

d

Jere

my

Bouj

enah

(FR)

S2-4

The

IVF-

lube

tria

l: Li

piod

ol u

terin

e

bath

ing

effe

ct fo

r enh

anci

ng th

e

resu

lts o

f in

vitr

o fe

rtili

satio

n, a

pilo

t ra

ndom

ised

tria

l

Neil

John

son

(NZ)

S3-2

Feta

l and

pos

tnat

al d

evel

opm

enta

l an

omal

ies

afte

r exp

osur

e to

end

omet

riosi

s

in u

tero

affe

ctin

g tw

o ge

nera

tions

not

ye

t acc

epte

d

Kath

y Sh

arpe

-Tim

ms

(US)

S3-3

Met

abol

ic re

prog

ram

min

g of

the

perit

onea

l m

esot

heliu

m b

y TG

F –

may

pro

mot

e

endo

met

riosi

s le

sion

dev

elop

men

t

Vick

y Ja

ne Y

oung

(UK)

S3-4

Loca

lizat

ion

of c

ellu

lar i

nter

actio

ns a

nd

neur

oang

ioge

nesi

s in

dee

ply

inva

sive

en

dom

etrio

sis

impl

icat

es im

port

ant r

ole

of

mac

roph

age

infil

trat

ion

Anto

nia

Fran

cisc

o (B

R)

V1-2

La

pras

copi

c E/

O ul

tral

ow re

ctal

, bla

dder

, pe

lvic

end

omet

riosi

s

Taha

ni A

lmot

rafi

(AU)

V1-3

Re

stric

tion

of e

ndom

etrio

sis

of th

e le

ft

late

ral i

nfra

ure

teric

and

sup

ra u

rete

ric

para

met

rium

Jenn

ifer U

zan

(FR)

V1-4

Ro

botic

ade

nom

yom

etct

omy

to p

rese

rve

th

e ut

erus

for f

utur

e pr

egna

ncy

Sa

ng H

oon

Kwon

(KR)

GOLD

EN

HALL

BALL

RO

OM 4

BALL

RO

OM 1

BALL

RO

OM 2

-3

Refr

eshm

ents

, pos

ter v

iew

ing

and

exhi

bits

15.3

0 -

16.0

0

S3-1

In

tra-

tissu

e es

trad

iol,

prog

este

rone

an

d te

stos

tero

ne c

once

ntra

tions

in

endo

met

riosi

s ar

e im

bala

nced

by

loca

l st

eroi

d m

etab

olis

m n

ot y

et a

ccep

ted

Kais

a Hu

htin

en (F

I)

V1-1

Su

rgic

al tr

eatm

ent o

f mul

tiple

site

s bo

wel

en

dom

etrio

sis

– ho

w w

e pe

rfor

m

Patri

ck B

elle

lis (B

R)

Page 23: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.4

8 –

17.0

0

17.0

0 –

17.1

2

17.1

2 –

17.2

4

17.2

4 –

17.3

0

17.3

0 –

18.3

0

S1-5

Part

ial r

esec

tion

of th

e ex

tras

eros

al

pelv

ic fa

scia

is a

cru

cial

sur

gica

l ste

p

in th

e m

anag

emen

t of p

atie

nts

with

co

lore

ctal

end

omet

riosi

s M

arco

s Ba

llest

er (F

R)

S2-5

Mat

erna

l per

itone

al fl

uid

sphi

ngol

ipid

s

in e

ndom

etrio

sis-

asso

ciat

ed in

fert

ility

Yi

e Ho

u Le

e (S

G)

S3-5

Endo

met

riosi

s an

d hi

gh ri

sk

of c

omor

bidi

ties:

Ana

lysi

s of

mor

e

than

hal

f mill

ion

patie

nts

Luiz

Fern

ando

Pin

a Ca

rval

ho (B

R)

V1-5

Bo

wel

end

omet

riosi

s –

Robo

tic tr

eatm

ent

with

dis

coid

rese

ctio

n –

the

tech

niqu

e Du

arte

Rib

eiro

(BR)

S1-6

Lapa

rosc

opic

man

agem

ent o

f dee

ply

in

filtr

atin

g en

dom

etrio

sis:

A c

ohor

t pr

ospe

ctiv

e st

udy

with

10-

year

follo

w u

p Ji

nhua

Len

g (C

N)

S1-7

Lapa

rosc

opic

neu

rolis

ys fo

r dee

p

endo

met

riosi

s in

filtr

atin

g pe

lvic

wal

l an

d so

mat

ic n

erve

s: A

retr

ospe

ctiv

e

stud

y on

26

patie

nts

Robe

rto C

lariz

a (IT

)

Disc

ussi

on

S2-6

Patie

nt s

atis

fact

ion

conc

erni

ng a

ssis

ted

repr

oduc

tive

tech

nolo

gy tr

eatm

ent i

n

mod

erat

e to

sev

ere

endo

met

riosi

s

not y

et a

ccep

ted

Lise

tte v

an d

er H

ouw

en (N

L)

S2-7

Perit

onea

l end

omet

riosi

s an

d al

lelic

fr

eque

ncy

of G

DF-9

(rs2

5428

5, rs

2542

86,

rs10

4912

79),

anti-

mul

leria

n ho

rmon

e an

d re

cept

or (A

MHR

2) g

enes

sin

gle

not y

et

acce

pted

Em

ily D

e Co

nto

(BR)

Disc

ussi

on

S3-6

The

endo

cann

abin

oid

syst

em m

odul

ates

en

dom

etrio

sis

deve

lopm

ent i

n a

mou

se

mod

el: I

nves

tigat

ing

the

role

of t

he

CB1

rece

ptor

Paol

a Pa

nina

(IT)

S3-7

Nerv

e fib

er a

nd ly

mph

oid

nodu

le

wer

e ob

serv

ed in

pat

holo

gica

l and

im

mun

ohis

tolo

gica

l ana

lysi

s of

cyn

omol

gus

mon

keys

(Mac

aca

fasc

icul

aris

) with

sp

onta

neou

s en

dom

etrio

sis

not y

et a

ccep

ted

Ayak

o Ni

shim

oto-

Kaki

uchi

(JP)

Disc

ussi

on

V1-6

Ad

vant

age

tech

nica

l ass

ocia

te o

f sha

ve

surg

ery

in th

e en

dom

etrio

sis

infil

trat

ing

segm

enta

l res

ectio

n

Univa

ldo

Saga

e (B

R)

V1-7

Th

ere

is m

ore

to e

ndom

etrio

sis

than

w

e ca

n se

e

Tam

er S

ecki

n (U

S)

Disc

ussi

on

Post

er s

essi

on w

ith re

fres

hmen

ts

GOLD

EN

HALL

BALL

RO

OM 4

BALL

RO

OM 1

BALL

RO

OM 2

-3

Surg

ical

The

rapy

Chai

rs |

Sony

Sin

gh (C

A) a

nd A

lan

Lam

(AU)

Infe

rtili

ty a

nd A

RTCh

airs

| Ed

gard

o Ro

lla (A

R) a

nd N

icol

au D

’Am

ico

(BR)

Path

ogen

esis

/ ae

tiolo

gyCh

airs

| Asg

i Faz

leaba

s (U

S) a

nd M

oham

ed B

edaiw

y (CA

)Vi

deo

Sess

ion

1Ch

airs

| Pe

ter M

aher

(AU)

and

Lis

elot

te M

ettle

r (DE

) 23

Page 24: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Frid

ay 2

May

201

4 0

7.00

- 1

5.30

07.0

0 –

07.0

5

07.0

5 –

07.2

0

07.2

0 –

07.3

5

07.3

5 –

07.5

5

08.0

0 –

08.2

0

08.2

0 –

08.3

5

08.3

5 –

08.5

0

08.5

0 –

09.0

5

09.0

5 –

09.2

0

09.2

0 –

09.3

5

09.3

5 –

10.0

0

10.0

0 –

10.3

0

10.3

0 –

11.0

0

B2-1

Insi

ghts

into

cur

rent

dru

g de

velo

pmen

t at B

ayer

O

liver

Mar

tin F

isch

er (D

E)

B2-2

Bey

ond

horm

onal

sup

pres

sion

: New

ther

apeu

tic a

venu

es in

end

omet

riosi

s re

sear

ch a

t Bay

er

Tho

mas

M. Z

olln

er (D

E)

B2-3

Sen

sitiz

atio

n an

d pa

in m

echa

nism

s in

end

omet

riosi

s

Kat

y Vi

ncen

t (UK

)

Inno

vatio

n in

end

omet

riosi

s: p

ersp

ectiv

es fr

om a

cade

mia

and

indu

stry

Chai

r | C

harle

s Ch

apro

n (F

R)

Refr

eshm

ents

, pos

ter v

iew

ing

and

exhi

bits

Mec

hani

sms

of p

ain

Chai

rs |

Pam

ela

Stra

tton

(US)

and

Mic

hel C

anis

(FR)

M5-

0 M

echa

nism

s of

pai

n Sy

lvia

Mec

hsne

r (DE

)

Keyn

ote

lect

ure

3

Chai

rs |

Joa

o Sa

bina

Cun

ha-F

ilho

(BR)

and

Has

san

Salla

m (E

G)

Mat

erna

l pre

gnan

cy h

orm

ones

and

end

omet

riosi

s

Ivo B

rose

ns (B

E)

New

dru

gsCh

airs

| Fe

lice

Petra

glia

(IT)

and

Car

los

Petta

(BR)

M

6-0

Ne

w d

rugs

Erk

ut A

ttar (

TR)

M5-

1 Es

trog

en re

cept

or s

ubty

pe d

epen

dent

mac

roph

age

activ

atio

n le

ads

to a

sen

sory

ner

ve

outg

row

th in

per

itone

al e

ndom

etrio

sis

Julia

Arn

old

(DE)

M5-

4

Estr

ogen

rece

ptor

sub

type

s m

odul

ate

how

ner

ve fi

bres

influ

ence

blo

od v

esse

ls a

nd

mac

roph

ages

in p

erito

neal

end

omet

riosi

s Er

in G

reav

es (U

K)

M6-

2

Phar

mac

okin

etic

s of

ela

golix

, an

oral

gon

adot

ropi

n-re

leas

ing

horm

one

(GnR

H)

anta

goni

st ta

rget

ed in

the

trea

tmen

t of e

ndom

etrio

sis

and

uter

ine

leio

myo

mas

Ju

ki N

G (U

S)

M5-

5

Do c

linic

al p

ain

mea

sure

s co

rrel

ate

to s

ubco

rtic

al b

rain

vol

ume

in w

omen

w

ith c

hron

ic p

elvi

c pa

in?

Sara

h M

urra

y (U

K)

M6-

4

Inhi

bitio

n of

type

1 1

7ß-h

ydro

xyst

eroi

d-de

hydr

ogen

ase

impa

irs th

e sy

nthe

sis

of

est

roge

ns in

end

omet

riosi

s

Andr

ea R

oman

o (N

L)

M6-

5

Dual

-pro

gest

ogen

-del

iver

y sy

stem

s th

erap

y w

ith le

vono

rges

trel

intr

aute

rine

syst

em a

nd e

tono

gest

rel

subd

erm

al im

plan

t for

refr

acto

ry e

ndom

etrio

sis-

asso

ciat

ed p

elvi

c pa

in: a

n ef

fect

ive

new

ther

apy

Ce

cilia

Ng

(AU)

Ques

tions

, ans

wer

s an

d di

scus

sion

s on

futu

re re

sear

ch p

riorit

ies

Sylvi

a M

echs

ner (

DE)

Ques

tions

, ans

wer

s an

d di

scus

sion

s on

futu

re re

sear

ch p

riorit

ies

Erku

t Atta

r (TR

)

M6-

3

Targ

etin

g y-

box-

bind

ing

prot

ein

1 (Y

B-1)

for t

he tr

eatm

ent o

f end

omet

riosi

s

Cáss

ia G

isel

e Te

rrass

ani S

ilvei

ra (D

E)

M5-

2

Inhi

bitio

n of

PGE

2 re

cept

ors

EP2

and

EP4

decr

ease

s gr

owth

, inn

erva

tion

an

d no

cice

ptio

n of

end

omet

riosi

s Jo

e Ar

osh

(IN)

M5-

3

Nove

l mec

hani

sms

of n

ocic

eptio

n in

ani

mal

and

cel

l mod

els

of e

ndom

etrio

sis

Kr

iste

ena

Ray

(US)

M6-

1

Firs

t pep

tide-

base

d no

n-ho

rmon

al th

erap

y of

end

omet

riosi

s:

Whe

re a

re w

e to

day?

Vi

nay

Sing

h (C

A)

Spon

sore

d by

Spon

sore

d by

A lig

ht b

reak

fast

buffe

t will

be s

erve

d

GOLD

EN

HALL

GOLD

EN

HALL

BALL

RO

OM

BALL

RO

OM

Page 25: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Non-

inva

sive

dia

gnos

is

Chai

rs |

Moa

mar

Al-J

efou

t (JO

) and

Jos

e M

ende

s Al

drig

ht (B

R)M

7-0

No

n-in

vasi

ve d

iagn

osis

Ch

ristia

n Be

cker

(UK)

Futu

re p

ersp

ectiv

es o

n th

e di

agno

sis

and

trea

tmen

t of e

ndom

etrio

sis

Chai

rs |

Arno

ld A

dvin

cula

(US)

and

Ann

emie

k Na

p (N

L)

Man

agem

ent o

f pai

n an

d in

fert

ility

in d

eep

dise

ase

Chai

rs |

Axel

For

man

(DK)

and

Cha

rles

Chap

ron

(FR)

M8-

0

Man

agem

ent o

f pai

n an

d in

fert

ility

in d

eep

dise

ase

Ho

race

Rom

an (F

R)

M7-

1

Ultr

asou

nd m

appi

ng o

f pel

vic

endo

met

riosi

s: d

oes

the

loca

tion

and

num

ber o

f les

ions

af

fect

the

diag

nost

ic a

ccur

acy?

A m

ultic

entr

e di

agno

stic

acc

urac

y st

udy

To

m H

olla

nd (U

K)

M7-

4A

com

bine

d ap

proa

ch o

f ner

ve fi

ber d

etec

tion

plus

infr

ared

spe

ctro

scop

y pr

ofile

in

eut

opic

end

omet

rium

out

perf

orm

s th

e ca

paci

ty o

f eac

h si

ngle

tech

niqu

e to

no

n-in

vasi

vely

dia

gnos

e en

dom

etrio

sis

Raul

Gom

ez (E

S)

M8-

2En

zian

cla

ssifi

catio

n: D

oes

it co

rrel

ate

with

clin

ical

sym

ptom

s am

d th

e as

rm s

core

?Di

etm

ar H

aas

(AT)

M7-

5Hi

gh fi

delit

y fe

nom

ic c

lass

ifier

s to

dia

gnos

e an

d st

age

endo

met

riosi

s Li

nda

Giud

ice

(US)

M8-

4Va

lidat

ing

the

“Eco

syst

em”

for e

ndom

etrio

sis

Bern

ardo

Las

mar

(BR)

M8-

5 An

atom

ophy

siol

ogic

stu

dy o

f pat

ient

s w

ith p

elvi

c en

dom

etrio

sis

inte

stin

al in

volv

emen

tDo

ryan

e M

aria

Doe

Rei

s Li

ma

(BR)

Ques

tions

, ans

wer

s an

d di

scus

sion

s on

futu

re re

sear

ch p

riorit

ies

Chris

tian

Beck

er (U

K)Qu

estio

ns, a

nsw

ers

and

disc

ussi

ons

on fu

ture

rese

arch

prio

ritie

sHo

race

Rom

an (F

R)

M8-

3Ro

botic

-ass

iste

d la

paro

scop

y fo

r dee

p en

dom

etrio

sis:

Inte

rnat

iona

l mul

ticen

tric

retr

ospe

ctiv

e st

udy

Pier

re C

ollin

et (F

R)

M7-

2Ev

alua

tion

of a

n in

nova

tive

mod

el o

f car

e an

d de

dica

ted

serv

ice

for t

eena

gers

and

w

omen

with

per

iod

pain

, pel

vic

pain

and

end

omet

riosi

sM

elis

sa P

arke

r (AU

)

M7-

3Sc

reen

ing

tool

for e

arly

-sta

ge e

ndom

etrio

sis

in p

atie

nts

with

chr

onic

pel

vic

pain

Patri

ck J

r. Ye

ung

(US)

M8-

1Se

vere

ure

tera

l end

omet

riosi

s: p

relim

inar

y re

port

of 3

0 Ca

ses

With

Hyd

rone

phro

sis

Ro

drig

o Fe

rnan

des

(PT)

Keyn

ote

lect

ure

4 Ch

airs

| C

athe

rine

Alla

ire (C

A) a

nd J

uan

Salg

ado

(PR)

The

patie

nt’s

role

in m

edic

al d

ecis

ion

mak

ing

Debo

rah

Bush

(NZ)

Orga

nised

by

Supp

orte

d by

11.4

5 -

12.0

5

11.4

5 -

13.1

5

11.0

0 -

11.3

0

13.3

0 -

13.5

0

13.5

0 -

14.0

5

14.0

5 -

14.2

0

14.2

0 -

14.3

5

14.3

5 -

14.5

0

14.5

0 -

13.0

5

13.0

5 -

15.3

0

12.0

5 -

12.2

5

12.2

5 -

12.4

5

12.4

5 -

13.0

5

13.0

5 -

13.1

5

GOLD

EN

HALL

BALL

RO

OM

GOLD

EN

HALL

L2-1

MRI

as

a di

agno

stic

tool

for e

ndom

etrio

sis

G

erar

d Du

nsel

man

(NL)

L2-2

Ultr

asou

nd a

s a

diag

nost

ic to

ol fo

r end

omet

riosi

s

Mau

ricio

Abr

ao (B

R)

L2-3

The

futu

re o

f sur

gery

as

a tr

eatm

ent o

f end

omet

riosi

s

Jor

g Ke

ckst

ein

(AT)

L2-4

Tar

gete

d tr

eatm

ents

for e

ndom

etrio

sis

L

inda

Giu

dice

(US)

Ques

tions

and

ans

wer

s

GOLD

EN

HALL

A lig

ht lu

nch

will b

e se

rved

25

Page 26: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Frid

ay 2

May

201

4 1

5.30

- 1

8.30

16.0

0 –

16.1

2

16.1

2 –

16.2

4

16.2

4 –

16.3

6

16.3

6 –

16.4

8

Med

ical

ther

apy

Chai

rs |

Vivia

n Fe

rreira

do

Amar

al (B

R)

and

Thom

as D

’Hoo

ghe

(BE)

Diag

nosi

s an

d sc

reen

ing

Chai

rs |

Lind

a Gi

udic

e (U

S) a

nd

Anto

nio

Setu

bal (

PT)

Imm

unol

ogy

and

stem

cel

lsCh

airs

| Ta

suku

Har

ada

(JP)

and

Lo

uise

Hul

l (AU

)

Qual

ity o

f life

Chai

rs |

Neil

John

son

(NZ)

and

Ca

rlos

Calh

az-J

orge

(PT)

S4-2

The

asso

ciat

ion

of p

ycno

geno

l with

or

al c

ontr

acep

tives

for t

he tr

eatm

ent

of e

ndom

etrio

sis-

rela

ted

pain

Hugo

Mai

a Jr

. (BR

)

S4-1

Ar

e w

e fo

llow

ing

our n

atio

nal

endo

met

riosi

s cl

inic

al p

ract

ice

guid

elin

es?

A

Cana

dian

per

spec

tive

Mar

a So

bel (

CA)

S5-1

Th

e ro

le o

f the

gen

eral

pra

ctiti

oner

in th

e di

agno

stic

pro

cess

of D

utch

wom

en w

ith

endo

met

riosi

s

Anne

mie

k Na

p (N

L)

S4-3

Upda

te o

n ch

ange

s in

bon

e de

nsity

in

wom

en w

ith s

ympt

omat

ic e

ndom

etrio

sis

durin

g an

d af

ter t

reat

men

t with

leup

rolid

e ac

etat

e an

d no

reth

indr

one

acet

ate

Pam

ela

Stra

tton

(US)

S4-4

An a

ntip

roge

stin

, Cdb

-412

4, im

pact

s cy

clin

g an

d ho

rmon

es w

hich

may

lead

to a

llevi

atio

n of

sym

ptom

s of

end

omet

riosi

s

Rona

ld W

iehl

e (U

S)

S5-2

Dela

y in

clin

ical

dia

gnos

is o

r del

ay in

re

ferr

al fo

r ade

quat

e tr

eatm

ent:

Whi

ch h

as

a gr

eate

r im

pact

on

the

man

agem

ent o

f en

dom

etrio

sis?

David

Sor

iano

(IL)

S5-3

Com

mun

icat

ing

endo

met

riosi

s w

ith y

oung

w

omen

to d

ecre

ase

diag

nosi

s tim

e

Mel

issa

Par

ker (

AU)

S5-4

Eval

uatio

n of

the

biom

arke

r He4

as

a

diffe

rent

ial t

ool i

n pa

tient

s w

ith d

iffer

ent

stag

es o

f end

omet

riosi

s an

d ov

aria

n ca

ncer

Dorth

e Ha

rtwel

l (DK

)

S6-2

Char

acte

rizat

ion

of th

e su

bpop

ulat

ions

of

topi

c en

dom

etrio

tic ti

ssue

– a

put

ativ

e en

dom

etrio

tic s

tem

cel

l pop

ulat

ion?

Adria

na In

vitti

(BR)

S6-3

Regu

lato

ry T

cel

ls in

end

omet

riosi

s:

Pote

ntia

l rol

es in

pat

hoge

nesi

s

Mar

ina

Berb

ic (A

U)

S6-4

The

endo

met

rial s

tem

cel

l mar

kers

not

ch

and

num

b ar

e as

soci

ated

with

end

omet

riosi

s

Mar

tin G

ötte

(DE)

S7-2

En

dom

etrio

sis

impa

ct q

uest

ionn

aire

(Eiq

): Ne

w q

uest

ionn

aire

to m

easu

re lo

ng te

rm

impa

ct o

f end

omet

riosi

s on

wom

en’s

live

s

Mar

yam

Mor

adi (

AU)

S7-3

Th

e in

fluen

ce o

f dys

pare

unia

and

dy

smen

orrh

ea in

tens

ities

on

diffe

rent

do

mai

ns o

f wom

en’s

qua

lity

of li

fe q

uant

ified

th

roug

h SF

-36

and

EHP-

30 q

uest

ionn

aire

s

Mar

lon

de F

reita

s Fo

nsec

a (B

R)

S7-4

Af

fect

ed s

exua

l fun

ctio

ning

In w

omen

with

en

dom

etrio

sis

influ

ence

s se

xual

func

tioni

ng

of th

eir m

ale

part

ner a

nd le

ads

subs

eque

ntly

to

unc

erta

inty

In th

eir r

elat

ions

hip

Ai

sha

de G

raaf

f (NL

)

GOLD

EN

HALL

BALL

RO

OM 4

BALL

RO

OM 1

BALL

RO

OM 2

-3

Refr

eshm

ents

, pos

ter v

iew

ing

and

exhi

bits

15.3

0 -

16.0

0

S6-1

Ne

rve

repe

llent

fact

ors

affe

ct th

e in

flam

mat

ory

cond

ition

of e

ndom

etrio

sis

Sylvi

a M

echs

ner (

DE)

S7-1

Pe

rson

ality

cor

rela

tes

of e

ndom

etrio

sis

Yuva

l Kau

fman

(IL)

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16.4

8 –

17.0

0

17.0

0 –

17.1

2

17.1

2 –

17.2

4

17.2

4 –

17.3

0

S4-5

Prot

ein

kina

se in

hibi

tor v

emur

afen

ib

cont

rols

the

prog

ress

ion

of e

ndom

etrio

sis

in

vitr

o an

d in

viv

o Pi

etro

San

tulli

(FR)

S5-5

Com

paris

on b

etw

een

tran

svag

inal

ultr

asou

nd

with

bow

el p

repa

ratio

n an

d pe

lvic

mag

netic

re

sona

nce

imag

ing

for t

he d

iagn

osis

of d

eep

endo

met

riosi

s Ro

sa M

aria

Nem

e (B

R)

S6-5

Cyto

kine

rela

ted

to n

atur

al k

iller

and

T-

regu

lato

ry c

ells

hav

e a

diffe

rent

pro

file

in

dee

p en

dom

etrio

sis

Patri

ck B

elle

lis (B

R)

S7-5

Or

al p

rese

ntat

ion

- A lo

ng te

rm p

rosp

ectiv

e ob

serv

atio

nal s

tudy

of t

he im

pact

of

lapa

rosc

opic

exc

isio

n of

end

omet

riosi

s

on q

ualit

y of

life

par

amet

ers

King

shuk

Maj

umde

r (UK

)

S4-6

Long

term

trea

tmen

t with

letr

ozol

e af

ter

gnrh

a do

wn

regu

latio

n in

pre

men

opau

sal

wom

en w

ith m

oder

ate

and

seve

re

endo

met

riosi

s. A

saf

ety

and

effic

acy

stud

y Ju

lia B

artle

y (D

E)

S4-7

Eval

uatio

n of

the

effic

acy

of tw

o di

ffere

nt

oral

con

trac

eptiv

e fo

rmul

atio

ns a

dmin

iste

red

in a

con

tinuo

us fa

shio

n fo

r mod

erat

e to

se

vere

dys

men

orrh

ea: P

relim

inar

y re

sults

Th

iago

Per

eira

(BR)

S5-6

Thre

e-di

men

sion

al re

ctos

onog

raph

y:

Desc

riptio

n an

d ev

alua

tion

of a

3D

tr

ansv

agin

al e

chog

raph

y w

ith c

ontr

ast t

o as

sess

col

orec

tal e

ndom

etrio

sis

Gil D

uber

nard

(FR)

S5-7

Eval

uatio

n of

pla

sma

mic

rorn

as a

s

diag

nost

ic b

iom

arke

rs fo

r end

omet

riosi

s Zh

ao W

ang

(AU)

S6-6

Dend

ritic

cel

ls, t

he m

enst

rual

cyc

le a

nd

endo

met

riosi

s: C

ircul

atin

g an

d en

dom

etria

l po

pula

tions

Alis

on H

ey-C

unni

ngha

m (A

U)

S6-7

Expr

essi

on o

f ang

iote

nsin

rece

ptor

s

type

1 (A

t1)

type

2 (A

t2) M

rna

in lo

cal

endo

met

riosi

s le

sion

s

Take

hiro

Nak

ao (J

P)

S7-6

Di

ffere

nces

in p

ain

repo

rtin

g an

d

man

agem

ent b

etw

een

thre

e ge

ogra

phic

al

regi

ons

in a

cro

ss-s

ectio

nal s

tudy

in

patie

nts

with

end

omet

riosi

s (fe

elin

g)

Char

les

Chap

ron

(FR)

S7-7

Pr

eope

rativ

e SF

36 s

core

to d

ecid

e

a su

rgic

al a

ppro

ach

in p

atie

nt w

ith

chro

nic

pelv

ic p

ain

Mic

hel C

anis

(FR)

Post

er s

essi

on w

ith re

fres

hmen

ts

GOLD

EN

HALL

BALL

RO

OM 4

BALL

RO

OM 1

BALL

RO

OM 2

-3

Diag

nosi

s an

d sc

reen

ing

Chai

rs |

Lind

a Gi

udic

e (U

S) a

nd

Anto

nio

Setu

bal (

PT)

Imm

unol

ogy

and

stem

cel

lsCh

airs

| Ta

suku

Har

ada

(JP)

and

Lo

uise

Hul

l (AU

)

Qual

ity o

f life

Chai

rs |

Neil

John

son

(NZ)

and

Ca

rlos

Calh

az-J

orge

(PT)

Med

ical

ther

apy

Chai

rs |

Vivia

n Fe

rreira

do

Amar

al (B

R)

and

Thom

as D

’Hoo

ghe

(BE)

27

Page 28: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Satu

rday

3 M

ay 2

014

08.

00 -

11.

30

08.0

0 –

08.2

0

08.2

0 –

08.3

5

08.3

5 –

08.5

0

08.5

0 –

09.0

5

09.0

5 –

09.2

0

09.2

0 –

09.3

5

09.3

5 –

10.0

0

10.0

0 –

10.3

0Re

fres

hmen

ts, p

oste

r vie

win

g an

d ex

hibi

ts

Endo

met

riosi

s an

d ca

ncer

Chai

rs |

Ludw

ig K

iese

l (DE

) and

Lin

da G

riffit

h (U

S)M

9-0

Endo

met

riosi

s an

d ca

ncer

Br

uno

Borg

hese

(FR)

Prev

entio

n an

d m

anag

emen

t of r

ecur

renc

esCh

airs

| M

ette

Moe

n (N

O) a

nd J

ohan

nes

Ever

s (N

L)M

10-0

Pr

even

tion

and

man

agem

ent o

f rec

urre

nces

Ka

ori K

oga

(JP)

M9-

1 Cl

inic

al a

naly

sis

of o

varia

n ep

ithel

ial c

arci

nom

a w

ith c

oexi

stin

g

pelv

ic d

ndom

etrio

sis

Lin

Qiu

(CN)

M9-

4

Mm

p-3

med

iate

d en

dom

etrio

tic s

igna

lling

: Goo

d or

evi

l?

Pram

athe

s Da

sMah

apat

ra (I

N)

M10

-2

Occu

lt en

dom

etrio

sis:

An

unde

tect

able

find

ing

by la

paro

scop

y in

nor

mal

per

itone

um

Khal

eque

Kha

n (J

P)

M9-

5

Do O

varia

n ca

ncer

and

end

omet

riosi

s –

Shar

ing

alte

red

gene

tic p

athw

ays?

Da

niel

Den

tillo

(BR)

M10

-4

The

asso

ciat

ion

betw

een

sym

ptom

s an

d su

rgic

al fi

ndin

gs in

wom

en w

ith s

uspe

cted

end

omet

riosi

sa

Uche

Men

akay

a (A

U)

M10

-5

Anti-

angi

ogen

esis

of g

reen

tea

and

pote

ntia

ls o

f pro

drug

of e

piga

lloca

tchi

n-3-

galla

te (P

ro-E

gcg)

as

a n

ovel

ant

i-ang

ioge

nesi

s ag

ent f

or e

ndom

etrio

sis

Ch

i Chi

u W

ang

(HK)

Ques

tions

, ans

wer

s an

d di

scus

sion

s on

futu

re re

sear

ch p

riorit

ies

Brun

o Bo

rghe

se (F

R)

Ques

tions

, ans

wer

s an

d di

scus

sion

s on

futu

re re

sear

ch p

riorit

ies

Kaor

i Kog

a (J

P)

M10

-3

Endo

met

riotic

lesi

ons

reca

pitu

late

wou

nd h

ealin

g by

recr

uitin

g pl

atel

ets

Su

n-W

ei G

uo (C

N)

M9-

2

Endo

met

riosi

s an

d ca

ncer

: How

sho

uld

we

look

to th

is a

ssoc

iatio

n? B

af25

0A

and

canc

er-r

elat

ed c

hem

okin

es e

xpre

ssio

n in

end

omet

riosi

s le

sion

s an

d pe

lvic

ly

mph

nod

es

Giul

iano

Bor

relli

(BR)

M9-

3

Endo

met

riosi

s an

d ov

aria

n ca

ncer

: An

inte

rnat

iona

l poo

led

anal

ysis

Ro

berta

Nes

s (U

S)

M10

-1

Endo

met

riosi

s: A

n in

tern

atio

nal h

ealth

issu

e to

o bi

g to

igno

re -

pre

vent

ive

prog

ram

s in

tegr

al to

a m

ulti-

disc

iplin

ary

appr

oach

to tr

eatm

ent,

a Ne

w Z

eala

nd m

odel

De

bora

h Bu

sh (N

Z)

GOLD

EN

HALL

BALL

RO

OM

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10.3

0 –

10.4

2

10.4

2 –

10.5

4

10.5

4 –

11.0

6

11.0

6 –

11.1

8

Endo

met

rium

Chai

rs |

Hila

ry C

ritch

ley

(UK)

an

d W

arre

n No

thni

ck (U

S)

Epid

emio

logy

Chai

rs |

Stac

ey M

issm

er (U

S)

and

Mic

hel M

uelle

r (CH

)

Gene

tics,

epi

gene

tics,

an

d he

redi

tary

asp

ects

Chai

rs |

Andr

ew H

orne

(UK)

and

Ser

gio

Podg

aec

(BR)

Vide

o Se

ssio

n 2

Chai

rs |

Regi

nald

o Lo

pes

(BR)

an

d Ta

mer

Sec

kin

(US)

S8-2

Alte

red

mol

ecul

ar p

heno

type

s of

eut

opic

en

dom

etria

l mes

ench

ymal

ste

m c

ells

and

st

rom

al fi

brob

last

s in

end

omet

riosi

s

Lind

a Gi

udic

e (U

S)

S8-1

Ra

tiona

l des

ign

of s

ynth

etic

ext

race

llula

r m

atrix

(Ecm

) mic

roen

viro

nmen

ts th

at fo

ster

en

dom

etria

l epi

thel

ial c

ell p

olar

ity, f

unct

ion,

an

d st

rom

al c

ross

talk

for i

n vi

tro

and

in

vivo

use

Lind

a Gr

iffith

(US)

S9-1

En

dom

etrio

sis

rela

ted

qual

ity o

f lif

e ou

tcom

es a

re h

ighl

y in

fluen

ced

by

recr

uitm

ent s

trat

egie

s

Aish

a de

Gra

aff (

NL)

S8-3

The

orig

ins

of p

roge

ster

one

resi

stan

ce in

en

dom

etrio

sis:

sile

ncin

g of

pro

gest

eron

e ac

tion

at m

enst

ruat

ion

Bruc

e Le

ssey

(US)

S8-4

Mic

rorn

a M

ir-14

2-3P

regu

late

s

proi

nflam

mat

ory

sign

alin

g in

en

dom

etria

l str

oma

cells

Mar

tin G

ötte

(DE)

S9-2

Smok

ing

effe

cts

on p

ain

sym

ptom

s an

d fe

rtili

ty in

pat

ient

s w

ith e

ndom

etrio

sis

Luci

ana

Anto

niol

li (B

R)

S9-3

Inci

denc

e an

d co

st o

f sur

gery

for

endo

met

riosi

s in

Can

ada

iden

tified

us

ing

a na

tiona

l dat

abas

e

Cath

erin

e Al

laire

(CA)

S9-4

Endo

met

riosi

s he

alth

car

e: D

ispa

ritie

s in

ac

cess

to c

are

in w

omen

from

Pue

rto

Rico

Jess

ica

Four

quet

(PR)

S10-

2Ep

igen

etic

and

gen

omic

ana

lyse

s of

hu

man

feta

l mem

bran

es fr

om p

regn

ant

endo

met

riosi

s-af

fect

ed w

omen

Loui

s M

arce

llin (F

R)

S10-

3Ge

nom

e-w

ide

anal

ysis

of m

ethy

lom

e

reve

als

larg

e ep

igen

etic

alte

ratio

ns

in e

ndom

etrio

sis

Brun

o Bo

rghe

se (F

R)

S10-

4Ab

erra

nt d

na m

ethy

latio

n pr

ofile

s an

d pa

ttern

s of

hum

an e

utop

ic e

ndom

etriu

m in

en

dom

etrio

sis

and

its a

ssoc

iatio

n w

ith o

ther

re

gula

tory

ele

men

ts

Saha

r Hou

shda

ran

(US)

V2-2

Ca

se re

port

of a

bdom

inal

wal

l en

dom

etrio

sis

man

aged

lapa

rosc

opic

ally

Rodr

igo

Fern

ande

s (P

T)

V2-3

Su

rgic

al tr

eatm

ent o

f bla

dder

en

dom

etrio

sis

asso

ciat

ed w

ith

exte

rnal

ade

nom

yosi

s

Patri

ck B

elle

lis (B

R)

V2-4

Ro

botic

app

roac

h fo

r the

trea

tmen

t of t

he

ovar

ian

dndo

met

riom

a - T

he te

chni

que

Duar

te R

ibei

ro (B

R)

GOLD

EN

HALL

BALL

RO

OM 4

BALL

RO

OM 1

BALL

RO

OM 2

-3

S10-

1

Over

expr

essi

on o

f P27

Kip1

in c

ultu

red

endo

met

rial c

ells

from

pat

ient

s w

ith

endo

met

riosi

s no

rmal

izes

ang

ioge

nic

fact

ors

expr

essi

on

Adria

na In

vitti

(BR)

V2-1

A

new

exc

isio

n pr

oced

ure

for l

ow a

nd

mid

rect

al e

ndom

etrio

sis

nodu

les

usin

g co

mbi

ned

tran

sana

l and

lapa

rosc

opic

ap

proa

ch

Hora

ce R

oman

(FR)

11.1

8 –

11.3

0

10.4

2 –

10.5

4

S8-5

De

crea

se in

not

ch 1

con

trib

utes

to

impa

ired

deci

dual

izat

ion

asso

ciat

ed

with

end

omet

riosi

s

Asgi

Faz

leab

as (U

S)

S9-5

Pe

lvic

infla

mm

ator

y di

seas

e in

wom

en

with

end

omet

riosi

s is

mor

e se

vere

than

in

thos

e w

ithou

t

David

Sor

iano

(IL)

S10-

5

Varia

bilit

y of

gen

ome-

wid

e ge

ne

expr

essi

on a

nd d

na m

ethy

latio

n va

lues

ac

ross

tiss

ue s

ampl

es fr

om w

omen

with

an

d w

ithou

t end

omet

riosi

s

Alex

ande

r W D

rong

(UK)

V2-5

St

anda

rdiz

atio

n of

vid

eola

paro

scop

ic

surg

ery

for d

eep

endo

met

riosi

s by

co

lore

ctal

sur

geon

Univa

ldo

Saga

e (B

R)

29

Page 30: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

27 Satu

rday

3 M

ay 2

014

11.

30 -

15.

15

11.3

0 –

11.4

2

11.4

2 –

11.5

4

Endo

met

rium

Chai

rs |

Hila

ry C

ritch

ley

(UK)

an

d W

arre

n No

thni

ck (U

S)

Epid

emio

logy

Chai

rs |

Stac

ey M

issm

er (U

S)

and

Mic

hel M

uelle

r (CH

)

Gene

tics,

epi

gene

tics,

an

d he

redi

tary

asp

ects

Chai

rs |

Andr

ew H

orne

(UK)

and

Ser

gio

Podg

aec

(BR)

Vide

o Se

ssio

n 2

Chai

rs |

Regi

nald

o Lo

pes

(BR)

an

d Ta

mer

Sec

kin

(US)

S8-6

Prot

ein

oxid

atio

n le

vels

and

sup

erox

ide

dism

utas

e ac

tivity

in w

omen

with

infe

rtili

ty

rela

ted

to e

ndom

etrio

sis

Mar

icel

a Vi

ola-

Rhen

als

(CO)

S9-6

En

dom

etrio

tic w

omen

pre

sent

an

in

crea

sed

prev

ious

spo

ntan

eous

ab

ortio

ns ra

te

Piet

ro S

antu

lli (F

R)

S8-7

Dete

ctio

n of

ner

ve fi

bers

in e

ndom

etriu

m

topi

c to

aid

in th

e di

agno

sis

of e

ndom

etrio

sis

Mig

uel G

obbi

(BR)

S9-7

Bene

fits

of o

ral c

ontr

acep

tives

in

dysm

enor

rhea

and

dys

pare

unia

: Ca

se-c

ontr

ol s

tudy

in m

edic

al s

tude

nts

of

Coi

mbr

a un

iver

sity

, Por

tuga

l

Mar

garid

a Di

as (P

T)

S10-

7Va

lidat

ion

of h

isto

ne 3

and

his

tone

4 ly

sine

tr

i-met

hyla

tion

stat

us o

f end

omet

riosi

s le

sion

s

Jani

ce B

arro

s-M

onte

iro (P

R)

V2-7

Up

date

on

robo

tics

and

endo

met

riosi

s –

Wha

t is

the

curr

ent s

tate

?

Char

les

Mille

r (US

)

GOLD

EN

HALL

BALL

RO

OM 4

BALL

RO

OM 1

BALL

RO

OM 2

-3

S10-

6

An It

alia

n as

soci

atio

n st

udy

confi

rms

prev

ious

gw

as d

ata

supp

ortin

g ve

zt a

s su

scep

tibili

ty lo

cus

for e

ndom

etrio

sis

Paol

a Vi

gano

(IT)

V2-6

St

age

Iv e

ndom

etrio

sis

and

left

uter

olys

is

Taha

ni A

lmot

rafi

(AU)

12.1

5 –

13.1

5

12.3

5 –

12.5

5

The

role

of m

enst

rual

infl

amm

atio

n in

the

path

ogen

esis

of e

ndom

etrio

sis

sym

ptom

s an

d th

e ef

ficac

y of

con

tinuo

us re

gim

ens

of o

ral

cont

race

ptiv

es to

indu

ce a

men

orrh

ea

Hugo

Mai

a (B

R)

The

impa

ct o

f am

enor

rhea

on

the

qual

ity o

f life

of e

ndom

etrio

sis

patie

nts

Elia

no P

ellin

i (BR

)

The

impo

rtan

ce o

f am

enor

rhea

in th

e m

anag

emen

t of e

ndom

etrio

sis

Spon

sore

d by

BALL

RO

OM BALL

RO

OM

13.3

0 –

14.0

0

14.0

0 –

14.3

0

14.3

0 -

15.1

5

Keyn

ote

lect

ure

5

Chai

rs |

David

Ada

mso

n (U

S) a

nd L

uk R

omba

uts

(AU)

WER

F EP

Hect

: glo

bal h

arm

onis

atio

n of

rese

arch

St

acey

Mis

smer

(US)

Keyn

ote

lect

ure

6

Chai

rs |

Paul

o Ay

roza

Gal

vao

Ribe

iro (B

R) a

nd R

onal

d Ba

tt (U

S)

Defin

itive

sur

gery

: why

, whe

n, a

nd h

ow?

To

mm

aso

Falc

one

(US)

Clos

ing

Cere

mon

y

12.5

5 -

13.1

5Qu

estio

ns a

nd a

nsw

ers

A lig

ht lu

nch

will b

e se

rved

12.1

5 –

12.3

5

BALL

RO

OM

BALL

RO

OM

Page 31: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Closing ceremony

CHAIRS | Neil Johnson (NZ), Mauricio Abrao (BR) and Linda Giudice (US)

14.30

14.45

15.00

15.15

Summary of the highlights of WCE2014 and presentation on behalf of SBE of the award for best video presentation Rui Ferriani (BR)

Turning over a new leaf: welcome to the 13th World Congress on Endometriosis in 2017 Catherine Allaire (CA)

Close

Presentation of the Rodolphe Maheux and David Healy Awards Linda Giudice (US)

Thank you Mauricio Abrao (BR)

14.55

Page 32: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Exhi

bito

r

Stan

d #

Abbv

ie

21

Amge

n

4

Astra

Zene

ca

1

Baye

r Hea

lthca

re

19

ConM

ed

Ta

ble

Covid

ien

20

Ethi

con

5

Livr

aria

Reb

ram

ed

Tabl

e

Patie

nt S

ocie

ties

3

Stor

z

17

Stra

ttner

16

WCE

2017

18

SBE

2

32

Exhi

bito

r / p

oste

r floo

r pla

n

Page 33: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

WCE2014 Sponsors

AbbvieAbbVie is a global, research-based biopharmaceutical company formed

in 2013 following separation from Abbott. The company’s mission is to

use its expertise, dedicated people and unique approach to innovation

to develop and market advanced therapies that address some of the

world’s most complex and serious diseases. In 2013, AbbVie employs

approximately 21,000 people worldwide and markets medicines in

more than 170 countries. For further information on the company and

its people, portfolio and commitments, please visit www.abbvie.com.

Follow @abbvie on Twitter or view careers on our Facebook or Linke-

dIn page.

AbbVie Inc.

1 North Waukegan Road, North Chicago, IL 60064

USA

www.abbvie.com

33

AstraZeneca AstraZeneca is a global, innovation-driven biopharmaceutical business

that focuses on the discovery, development and commercialisation

of prescription medicines, primarily for the treatment of cardiovascular,

metabolic, respiratory, inflammation, autoimune, oncology, infection

and neuroscience diseases. AstraZeneca operates in over 100 countries

and its innovative medicines are used by millions of patients worldwide.

For more information please visit: www.astrazeneca.com

AstraZeneca do Brasil Ltda.

Rodovia Raposo Tavares, km 26,9 – Moinho Velho, Cotia/SP –

CEP: 06707-000

www.astrazeneca.com.br

Bayer HealthcareThe Bayer Group is a global enterprise with core competencies in the fields

of health care, agriculture and high-tech materials. Bayer HealthCare, a

subgroup of Bayer AG with annual sales of EUR 18.9 billion (2013), is one of

the world’s leading, innovative companies in the healthcare and medical

products industry and is based in Leverkusen, Germany. The company

combines the global activities of the Animal Health, Consumer Care,

Medical Care and Pharmaceuticals divisions. Bayer HealthCare’s aim is

to discover, develop, manufacture and market products that will improve

human and animal health worldwide. Bayer HealthCare has a global

workforce of 56,000 employees (Dec 31, 2013) and is represent-

ed in more than 100 countries. More information is available at

www.healthcare.bayer.com

Bayer Healthcare, Bayer Pharma AG

13342 Berlin, GERMANY

www.bayerpharma.com

BergamoBergamo, uma subsidiária Amgen

Av. das Nações Unidas, 14.171, 22º Andar,

Torre Crystal. Vl. Gertrudes.

São Paulo – SP – CEP: 04794-000

www.amgenbrasil.com.br

BMR Medical LtdaAv. Candido Hartmann, 570 Cj.174

Mercês

CEP 80.730-440

Curitiba,Paraná, Brasil

Industrial Site: BR 116, 400 (Km 1)

Campina Grande do Sul

www.bmrmedical.com.br

Page 34: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

34

WCE2014 Sponsors

EthiconAt Ethicon, we’re working to redefine surgery to change the world

for the better. We share an enduring commitment to advance surgical

care so more patients live longer, more fulfilling lives. And we are con-

tinuously evolving to better serve our customers. This commitment is

founded upon three key ideas:

Partnering for meaningful solutions: For almost a century, from

leading-edge sutures and endocutters to comprehensive payor and

provider solutions.

Expanding care globally: With offices, R&D Centers and manufactur-

ing facilities in more than 50 countries around the world.

People making a lasting difference: Our associates dedicate their

time and put their passion into helping hundreds of communities and

organizations across the globe

ETHICON

Rua Gerivatiba, 207, 12º ao 15º andares, Butantã, São Paulo, SP

www.ethicon.com

Covidien Covidien is a leading global healthcare products company that creates

innovative medical solutions for better patient outcomes and delivers

value through clinical leadership and excellence.

Through to its many respected brands, including Autosuture, Valleylab,

and Kendall, and wide portfolio, we make doctors, nurses, pharmacists

and other medical professionals as effective as they can be by intro-

ducing new technology and products.

COVIDIEN

Av. Jornalista Roberto Marinho, 85 - 10º e 11º andares

Cidade Monções - São Paulo - SP

CEP: 04576-010

ConMedCONMED Corporation

525 French Road

Utica, NY 13502

USA

www.conmed.com

Karl Storz

KARL STORZ is a renowned manufacturer that is well established in

all fields of endoscopy and can be considered as market leader in rigid

endoscopy. The still family held company was founded in 1945 in Tut-

tlingen, Germany, and has grown to one with a worldwide presence and

6700 employees. KARL STORZ offers a range of both rigid and flexible

endoscopes for a broad variety of applications. Today’s product range

also includes fully integrated concepts for the OR and servicing.

KARL STORZ GmbH & Co. KG

Mittelstraße 8 D-78532 Tuttlingen

www.karlstorz.com

Page 35: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

WCE2014 Sponsors

LibbsLibbs is a 100% brazilian laboratory that operates with an important

class of gynecologists. We have an expressive line of oral contraceptives

such as Gestinol 28, a gestodene 75mcg and 30mcg ethinylestradiol

association.

Libbs Farmacêutica Ltda

Rua Josef kryss, 250

São Paulo SP CEP: 01140-050

Brazil

www.libbs.com.br

Strattner H. Strattner Company is very proud to be part of the development of the

Brazilian Medicine focusing on Minimally Invasive Surgery (MIS). Since

1950, the company offers to Brazilian doctors the best MIS solutions

and products, exclusively representing worldwide medical devices

companies™ leaders: Karl Storz Endoskope, Storz Medical, MTP,

Intuitive Surgical, Medisafe, SciCan, Swann Morton, EDAP TMS, Trilux

and BK.

H. STRATTNER

Rua Ricardo Machado, 904 - São Cristóvão –

Rio de Janeiro- CEP: 20921-270

www.strattner.com.br

35

Page 36: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.00 to 18.30List of presenters

Abrao, Mauricio

Adamson, David

Advincula, Arnold

Albertsen, Hans

Albuquerque, Maria Eugenia

Alkatout, Ibrahim

Allaire, Catherine

Almotrafi, Tahani

Antoniolli, Luciana

Arnold, Julia

Arosh, Joe

Attar, Erkut

Ballester, Marcos

Barros-Monteiro, Janice

Bartley, Julia

Becker, Christian

Bellelis, Patrick

Berbic, Marina

Presenters PresentersSessions Sessions Page Page

PCC3-1

OC

L2-2

CC

PCC6-8

PCC3-14

M1-4

PCC2-6

PCC5-4

S9-3

CC

V1-2

V2-6

S9-2

M5-1

M5-2

M6-0

S1-5

S10-7

S4-6

M7-0

V1-1

S6-5

V2-3

S6-3

15

19

25

30

16

15

20

15

16

28

30

22

27

28

24

24

24

23

30

27

25

22

27

29

26

Blasbalg, Roberto

Borghese, Bruno

Borrelli, Giuliano

Boujenah, Jeremy

Brandão, Alice

Brosens, Ivo

Bush, Deborah

Canis, Michel

Campana, Colette

Carmona, Francisco

Carnevale Marin, Maria Lucia

Ceccaroni, Marcello

Chapron, Charles

PCC1-3

PCC1-11

M9-0

S10-3

M9-2

S2-3

PCC1-4

K3-0

K4-0

M10-1

PCC1-1

M10-1

M2-2

PCC4-6

M2-0

M3-1

PCC3-5

PCC3-7

S1-4

PCC4-4

L1-3

B2-4

S7-6

14

14

28

29

28

22

14

24

25

28

14

19

20

15

20

21

15

15

22

15

21

24

27

36

Page 37: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.00 to 18.30List of presenters

Clarizia, Roberto

Cohen, Jonathan

Collinet, Pierre

Cunha-Filho, Joao Sabino

Das Mahapatra, Pramathes

de Amaral, Vivian Ferreira

de Cicco, Carlo

de Conto, Emily

de Freitas Fonseca, Marlon

de Graaff , Aisha

de Mattos, Leandro Accardo

de Nicola, Ana Luisa Alencar

de Ziegler, Dominique

Dentillo, Daniel

Dias, Margarida

Dias, Junior Joao Antonio

Drong, Alexander W

Dubernard, Gil

Dunselman, Gerard

Falcone, Tommaso

Fazleabas, Asgi

PCC3-6

M2-4

S1-7

S2-2

M8-3

PCC6-7

M9-4

PCC6-2

PCC3-10

S2-7

S7-3

S7-4

S9-1

PCC1-2

PCC1-7

PCC1-3

PCC6-3

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Fernandes, Luiz

Fernandes, Rodrigo

Ferriani, Rui

Fischer, Oliver Martin

Fourquet, Jessica

Francisco, Antonio

Gargett, Caroline

Giudice, Linda

Gobbi, Miguel

Godlee, Fiona

Gomez, Raul

Goncalves, Manoel

Götte, Martin

Greaves, Erin

Griffith, Linda

PCC4-2

M8-1

V2-2

PCC6-5

CC

B2-1

S9-4

S3-4

M3-2

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OC

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Page 38: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.00 to 18.30List of presenters

Guo, Sun-Wei

Haas, Dietmar

Hartwell, Dorthe

Hey-Cunningham, Alison

Holland, Tom

van der Houwen, Lisette

Houshdaran, Sahar

Huhtinen, Kaisa

Ibrahim, Mohamed

Invitti, Adriana

Johnson, Neil

Kaufman, Yuval

Keckstein, Jörg

Khan, Khaleque

Kho, Rosanne

Kiesel, Ludwig

Klautau, Ana Paula

Koga, Kaori

Krentel, Harald

Kuepker, Wolfgang

M10-3

PCC5-6

M8-2

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S6-6

PCC1-9

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PCC3-4

PCC3-11

L2-3

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Presenters PresentersSessions Sessions Page Page

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Kwon, Sang Hoon

Lasmar, Bernardo

Lee, Yie Hou

Leng, Jinhua

Lessey, Bruce

Lima, Doryane Maria Dos Reis

Maia Jr, Hugo

Majumder, Kingshuk

Malzoni, Mario

Marcellin , Louis

Matsumoto, Kanako

Mechsner, Sylvia

Menakaya, Uche

Mettler, Liselotte

Miller, Charles

Missmer, Stacey

Montgomery, Grant

Moradi, Maryam

Morris, Andrew

Mueller, Michel

Murray, Sarah

V1-4

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Page 39: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.00 to 18.30List of presenters

Myung, Lydia

Nakao, Takehiro

Nap, Annemiek

Navarro, Paula

Neme, Rosa Maria

Ness, Roberta

Ng, Juki

Ng, Cecilia

Nishimoto-Kakiuchi, Ayako

Nyegaard, Mette

Oliveria, Marco Aurelio

Oppelt, Peter

Padovesi, Igor

Panina, Paola

Parker, Melissa

Pellini, Miguel

Pereira, Ana Maria

Pereira, Thiago

Petracco, Rafaella

Petraglia, Felice

Petta, Carlos

PCC2-2

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Pina de Carvalho, Luiz Fernando

Podgaec, Sergio

Popov, Aleksander

Pouly, Jean Luc

Qiu, Lin

Rahmioglu, Nilufer

Ray, Kristeena

Reis, Fernando

Renner, Stefan

Ribeiro, Paulo Ayroza

Ribeiro, Duarte

Riiskjaer, Mads

Roman, Horace

Romano, Andrea

Romeo, Armando

Sagae, Univaldo

K1-0

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Page 40: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

16.00 to 18.30List of presenters

Saha, Rama

Santulli, Pietro

Sardá, Jamir

Sarrel, Sallie

Schor, Eduardo

Seckin, Tamer

Sharpe-Timms, Kathy

Shebl, Omar

Singh, Sony

Singh, Vinay

Sobel, Mara

Somigliana, Edgardo

Soriano, David

Stepp, Kevin

Stratton, Pamela

Taylor, Hugh

Terrassani Silveira, Cássia Gisele

Thiruchelvam, Uma

Tsunada, Audrey

Uzan, Jennifer

M1-3

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Vercellini, Paolo

Vigano, Paola

Vincent, Katy

Viola-Rhenals, Maricela

Wang, Zhao

Wang, Chi Chiu

Wiehle, Ronald

Wu, Clara

Xu, Bing

Yeung, Patrick Jr.

Young, Scott

Young, Vicky Jane

Zollner, Thomas M.

Zondervan, Krina

OC

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Page 41: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Save the date now for the next world event in endometriosis, presided over by Catherine Allaire with honorary president Victor Gomel.

www.endometriosis.ca/wce2017

1 3 T H W O R L D C O N G R E S S

Tu r n i n g o v e r a n e w l e a f

O N E N D O M E T R I O S I S

Page 42: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Where to go for lunchThe WTC Convention Centre offers a wide

variety of places to have lunch within the D&D

Decoration and Design Centre.

• Coffee shops and chocolate stores:

BonCafé, Kopenhagen.

• Fast Food:

Bon Grille, Gendai, Mc Donald’s,

Rizzo Gourmet, Viena Express and

Vivenda do Camarão.

• Restaurants:

Andiamo, Badaró, Barbacoa Grill,

Bon Restô and Sweet Pimenta.

Where to go for dinnerKaa Restaurante - Av. Juscelino

Kubitschek, 279 - Vila Olimpia

The Kaa restaurant - is inspired by the

French-Italian cuisine combined with Brazilian

ingredients. Situated in the bustling Juscelino

Kubitschek Avenue, it is recognized for its

stunning architecture.

Sky Bar - Restaurante do Hotel Unique

- Avenida Brigadeiro Luis Antonio, 4700 -

Jardim Paulista

Located on the rooftop of the hotel, Skye

boasts a crimson red pool with an underwater

sound system and lounge area with stunning

views over Ibirapuera Park and the entire São

Paulo skyline. At Skye, innovative, delicious

food and drink by Chef Emmanuel Bassoleil,

visual exuberance, and legendary Unique

service engage all the senses.

Figueira Rubaiyat - R. Hadock Lobo, 1738 -

Cerqueira César

It is a restaurant postcard because of the

giant fig tree and Centennial, whose branches

spread throughout the hall that can be seen

from the street.

Barbacoa Churrascaria - Av. das Nações

Unidas, 12.555 – Piso Boulevard – Loja 122 e

124 - Brooklin - Event Location

Barbacoa is a chain of steakhouses, and the

D&D is located within one of São Paulo’s

busiest malls. It features an exclusive outside

entrance and valet parking. It offers more than

20 different cuts of beef, seafood and poultry

served a la carte, plus a salad buffet with more

than 40 ingredients.

What to do in São PaoloSão Paulo is a rich and vibrant city, not only

the commercial capital of Brazil, but also one

of the most culturally diverse cities in South

America. São Paulo is host to not only to

Brazilians, but also a host of other nations,

including the largest settlement of Japanese

people outside of Japan.

Here are a few ideas of experiences of this

magnificent city that you can gain whilst here

for the congress:

MASP (Museu de Arte de São Paulo)

São Paulo has many great museums, but

MASP is the city’s best art museum. It holds

the finest collection of Western art in Latin

America and hosts fantastic temporary

exhibitions. Tuesdays are free to the public.

Pinacoteca do Estado

Another lovely museum in São Paulo, the Pina-

coteca houses a huge collection of Brazilian art

that serves as a visual story of the country’s

history and cultural evolution, as well as a nice

collection of 19th century French sculpture.

The museum has a beautiful café downstairs

and is connected to Parque da Luz, a public

park that includes outdoor sculptures and a

European-style garden area (that are shared

with some unusual characters).

Soccer Museum

The Museu de Futebol is located in Estadio

Pacaembu, one of the city’s largest soccer

stadiums. If you love soccer, you will enjoy the

vintage soccer displays, interactive exhibits,

and celebrations of World Cup history and

Brazilian soccer stars. As you exit, there is a

nice gift shop and a café with live music on

most weekends. Admission is about $3 and

the museum is open Tuesday to Sunday.

Benedito Calixto all-day market

on Saturdays

The Calixto outdoor market goes all day on

Saturdays, with antiques and handicrafts

vendors starting in the morning and live music

and dancing starting around noon in the

market’s central food court. The live music is

chorinho, a very Brazilian style of music that is

samba-influenced, and many people go to the

market just for this.

Emergency telephone numbersTherefore please ensure you keep your

belongings with you at all times and refrain

from carrying laptops, cameras and electronic

devices whilst outside. Emergency

numbers as follows:

• 11- Area code (São Paulo City

and metropolitan area)

• 192 – Health Emergency

• 190 – Military Police

• 147 – Civil Police

• 193 – Fire Department

42

Local information

Page 43: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

O NOSSO NOME É NOVO. O NOSSO COMPROMISSO PARA COM OS CUIDADOS DE SAÚDE NÃO PRECISA DE APRESENTAÇÃO.Poucas empresas chegam ao mundo tão preparadas para servir os doentes como a AbbVie. Somos uma nova empresa biofarmacêutica, emergindo da Abbott com uma história de 125 anos de cuidados de saúde aos doentes.

Para fazer evoluir a saúde global, a AbbVie une a experiência e a estabilidade de uma empresa farmacêutica de sucesso com o espírito científico inovador de uma empresa de biotecnologia. O nosso compromisso de oferecer soluções que têm um impacto notável na vida das pessoas continua o legado das nossas origens da Abbott.

Estamos orgulhosos de nos apresentarmos como AbbVie, mas nunca nos esquecemos de que o que fazemos é mais importante do que o nosso nome.

abbvie.pt

OUR NAME IS NEW. OUR COMMITMENT TO HEALTHCARE WILL NEED NO INTRODUCTION.Few enterprises arrive in the world as ready to serve patients as AbbVie. We are a new biopharmaceutical company, emerging from Abbott with a 125-year history of patient care.

To advance global healthcare, AbbVie unites the expertise and stability of a successful pharmaceutical company with the innovative scientific spirit of a biotech. Our commitment to deliver solutions that make a remarkable impact in people’s lives continues the legacy of our Abbott origins.

We’re proud to introduce ourselves as AbbVie, but we never forget that what we do is more important than what we’re named.

abbvie.com

© 2014 AbbVie Inc.

AbbVie Inc.1 North Waukegan RoadNorth Chicago, IL 60064United States of AmericaTel: +1 847.932.7900Fax: +1 302.655.5049

Page 44: Scientific Programme 30 April - 3 May 2014 - …endometriosis.ca/WCE2014-Scientific-Programme.pdfScientific Programme 30 April - 3 May 2014 Contents 16.00 to 18.30 Sponsors Welcome

Bayer welcomes you to São Paulo for

Lunchtime Symposium

Golden Hall11h45–13h15, Thursday 01 May 2014

Endometriosis management: individualization and the role of

Allurene®/Visanne®* (dienogest, 2mg)

Faculty: Carlos Petta (Brazil), Aleksandr Popov (Russia), Krina Zondervan (UK), Charles Chapron (France), Michael Mueller (Switzerland), Sony Singh (Canada)

*Visanne® is the international commercial name for Allurene®

Symposia sponsored by Bayer HealthCare

The World Congress on Endometriosis

G.WH.GT.03.2014.0053

ALLURENE®. DIENOGESTE. REG. MS – 1.7056.0088. INDICAÇÃO: TRATAMENTO DA ENDOMETRIOSE. CONTRAINDICAÇÕES: DISTÚRBIO TROMBOEMBÓLICO VE NOSO EM ATIVIDADE, PRESENÇA OU HISTÓRICO DE DOENÇA CARDIOVASCULAR E ARTERIAL, DIABETES MELLITUS COM ENVOLVIMENTO VASCULAR, PRESENÇA OU HISTÓRICO DE DOENÇA HEPÁTICA GRAVE ENQUANTO OS VALORES DA FUNÇÃO HEPÁTICA NÃO RETORNAREM AO NORMAL, PRESENÇA OU HISTÓRICO DE TUMOR HEPÁTICO (BENIGNO OU MALIGNO), SUSPEITA OU DIAGNÓSTICO DE NEOPLASIAS DEPENDENTES DE HORMÔNIOS SEXUAIS, SANGRAMENTO VAGINAL NÃO DIAGNOSTICADO, HIPERSENSIBILIDADE À SUBSTÂNCIA ATIVA OU A QUALQUER UM DOS COMPONENTES DA FORMULAÇÃO. ADVERTÊNCIAS E PRECAUÇÕES: ANTES DE INICIAR O TRATAMENTO COM ALLURENE®, DEVE-SE EXCLUIR A POSSIBILIDADE DE GRAVIDEZ. DURANTE O TRATAMENTO COM ALLURENE® A OVULAÇÃO É INIBIDA NA MAIORIA DAS PACIENTES. ENTRETANTO, ALLURENE® NÃO É UM CONTRACEPTIVO E CASO SEJA NECESSÁRIO PREVENIR A GRAVIDEZ, AS PACIENTES DEVEM SER ORIENTADAS A UTILIZAR MÉTODOS CONTRACEPTIVOS NÃO HORMONAIS (POR EXEMPLO, MÉTODO DE BARREIRA). COM BASE NOS DADOS DISPONÍVEIS, O CICLO MENSTRUAL RETORNA AO NORMAL DENTRO DE 2 MESES APÓS O TÉRMINO DO TRATAMENTO COM ALLURENE®. EM MULHERES COM HISTÓRICO DE GRAVIDEZ EXTRAUTERINA OU DE ALTERAÇÃO DA FUNÇÃO DAS TUBAS UTERINAS, O USO DE ALLURENE® DEVE SER DECIDIDO APENAS APÓS CUIDADOSA AVALIAÇÃO DA RELAÇÃO RISCO/BENEFÍCIO. COMO ALLURENE® É UM MEDICAMENTO QUE CONTÉM SOMENTE PROGESTÓGENO, DEVEM SER CONSIDERADAS AS PRECAUÇÕES E ADVERTÊNCIAS DE TODOS OS MEDICAMENTOS QUE CONTEM SOMENTE PROGESTÓGENO, EMBORA NEM TODAS ESTEJAM BASEADAS EM ACHADOS DOS ESTUDOS CLÍNICOS REALIZADOS COM ALLURENE®. CASO QUALQUER UMA DAS CONDIÇÕES/FATORES DE RISCO DESCRITAS A SEGUIR ESTEJA PRESENTE OU SE AGRAVE, DEVE-SE REALIZAR UMA ANÁLISE INDIVIDUAL DA RELAÇÃO RISCO/BENEFÍCIO ANTES DE INICIAR OU CONTINUAR O USO DE ALLURENE®: DISTÚRBIOS CIRCULATÓRIOS, TUMORES, ALTERAÇÕES NO PADRÃO DE SANGRAMENTO, HISTÓRICO DE DEPRESSÃO, DESENVOLVIMENTO DE HIPERTENSÃO CLINICAMENTE SIGNIFICATIVA DIABETES MELLITUS (SOBRETUDO HISTÓRICO DE DIABETES MELLITUS GESTACIONAL), E OCORRÊNCIA FOLÍCULOS OVARIANOS PERSISTENTES (CISTOS OVARIANOS FUNCIONAIS). RECORRÊNCIA DE ICTERÍCIA COLESTÁTICA E/OU PRURIDO OCORRIDO ANTERIORMENTE DURANTE UMA GRAVIDEZ OU DURANTE O USO ANTERIOR DE ESTEROIDES SEXUAIS REQUER A DESCONTINUAÇÃO DE ALLURENE®. MULHERES COM TENDÊNCIA A MELASMA/CLOASMA DEVEM EVITAR EXPOSIÇÃO AO SOL OU RADIAÇÃO ULTRAVIOLETA DURANTE O TRATAMENTO COM ALLURENE®. RECOMENDA-SE ACOMPANHAMENTO REGULAR, COM ATENÇÃO ESPECIAL À PRESSÃO ARTERIAL,MAMAS, ABDOME E ÓRGÃOS PÉLVICOS, INCLUINDO CITOLOGIA CERVICAL. ALLURENE® NÃO DEVE SER ADMINISTRADO A MULHERES GRÁVIDAS UMA VEZ QUE NÃO HÁ NECESSIDADE DE TRATAR A ENDOMETRIOSE DURANTE A GRAVIDEZ - CATEGORIA B: “ESTE MEDICAMENTO NÃO DEVE SER UTILIZADO POR MULHERES GRÁVIDAS SEM ORIENTAÇÃO MÉDICA OU DO CIRURGIÃO-DENTISTA”. A ADMINISTRAÇÃO DE ALLURENE® DURANTE A LACTAÇÃO NÃO É RECOMENDADA. REAÇÕES ADVERSAS: FREQUENTES: CEFALEIA, DESCONFORTO NAS MAMAS, HUMOR DEPRIMIDO, ACNE, NÁUSEA, AUMENTO DE PESO, DOR ABDOMINAL, CISTO OVARIANO, CONDIÇÕES ASTÊNICAS, FLATULÊNCIA, FOGACHOS, DISTÚRBIOS DO SONO, IRRITABILIDADE, SANGRAMENTO UTERINO/VAGINAL INCLUINDO GOTEJAMENTO, NERVOSISMO, PERDA DE LIBIDO, ALOPECIA, DOR NAS COSTAS, DISTENSÃO ABDOMINAL, VÔMITO, ENXAQUECA, HUMOR ALTERADO. POUCO FREQUENTES: RESSECAMENTO VULVOVAGINAL, DESEQUILÍBRIO DO SISTEMA NERVOSO AUTÔNOMO, CANDIDÍASE VAGINAL, PELE SECA, ANSIEDADE, DEPRESSÃO, DISTÚRBIO DA ATENÇÃO, CONSTIPAÇÃO, DESCONFORTO ABDOMINAL, INFLAMAÇÃO GASTRINTESTINAL, HIPERIDROSE, PRURIDO, DIARREIA, INFECÇÃO DO TRATO URINÁRIO, CORRIMENTO GENITAL, DOR PÉLVICA, EDEMA, ANEMIA, DIMI NUIÇÃO DE PESO, AUMENTO DE APETITE, OLHO SECO, ZUMBIDO, DISTÚRBIOS INESPECÍFICOS DO SISTEMA CIRCULATÓRIO, PALPITAÇÕES, HIPOTENSÃO, DISPNEIA, HUMOR ALTERADO, GENGIVITE, HIRSUTISMO, ONICÓLISE, CASPA, DERMATITE, CRESCIMENTO ANORMAL DE PELOS, REAÇÃO DE FOTOSSENSIBILIDADE, DISTÚRBIO DE PIGMENTAÇÃO, DOR NOS OSSOS, ESPASMOS MUSCULARES, DOR NA EXTREMIDADE, PESO NAS EXTREMIDADES, VULVOVAGINITE ATRÓFICA, MASSA MAMÁRIA, DOEN ÇA FIBROCÍSTICA DA MAMA, ENDURECIMENTO DA MAMA. INTERAÇÕES MEDICAMENTOSAS: INDUTORES OU INIBIDORES ENZIMÁTICOS INDIVIDUAIS (CITOCROMO P450), SUBSTÂNCIAS COM PROPRIEDADES DE INDUÇÃO ENZIMÁTICA (FENITOÍNA, BARBITÚRICOS, PRIMIDONA, CARBAMAZEPINA, RIFAMPICINA E POSSIVELMENTE TAMBÉM OXCARBAZEPINA, TOPIRAMATO, FELBAMATO, GRISEOFULVINA, NEVIRAPINA E ERVA-DE-SÃO-JOÃO), SUBSTÂNCIAS COM PROPRIEDADES DE INIBIÇÃO ENZI MÁTICA (ANTIFÚNGICOS AZÓLICOS, CIMETIDINA, VERAPAMIL, MACROLÍDEOS, DILTIAZEM, INIBIDORES DA PROTEASE, ANTIDEPRESSIVOS E SUCO DE TORONJA). COM BASE EM ESTUDOS DE INIBIÇÃO IN VITRO, É IMPROVÁVEL QUE HAJA INTERAÇÃO CLINICAMENTE RELEVANTE ENTRE ALLURENE® E O METABOLISMO DE OUTROS MEDICAMENTOS MEDIADO PELA ENZIMA DO CITOCROMO P450. O USO DE PROGESTÓGENOS PODE INFLUENCIAR OS RESULTADOS DE CERTOS EXAMES LABORA TORIAIS, INCLUINDO PARÂMETROS BIOQUÍMICOS DO FÍGADO, TIREOIDE, FUNÇÃO RENAL E ADRENAL, NÍVEIS PLASMÁTICOS DE PROTEÍNAS (CARREADORAS), POR EXEMPLO, FRAÇÕES LIPOPROTEICAS/LIPÍDICAS, PARÂMETROS DO METABOLISMO DE CARBOIDRATOS E PARÂMETROS DA COAGULAÇÃO E FIBRINÓLISE. DE MODO GERAL, AS ALTERAÇÕES PERMANECEM DENTRO DA FAIXA LABORATORIAL NORMAL. POSOLOGIA: UM COMPRIMIDO POR DIA SEM INTERVALO DE PAUSA, TOMADO, PREFERENCIALMENTE, NO MESMO HORÁRIO TODOS OS DIAS, COM UM POUCO DE LÍQUIDO, SE NECESSÁRIO, INDEPENDENTEMENTE DE SANGRAMENTO VAGINAL. AO TÉRMINO DE UMA CARTELA, A PRÓXIMA DEVE SER INICIADA, SEM INTERRUPÇÃO. A INGESTÃO DOS COMPRIMIDOS PODE SER INICIADA EM QUALQUER DIA DO CICLO MENSTRUAL. VENDA SOB PRESCRIÇÃO MÉDICA.CONTRAINDICAÇÕES: DISTÚRBIOS CARDIOVASCULARES, DIABETES MELLITUS COM ENVOLVIMENTO VASCULAR. INTERAÇÕES MEDICAMENTOSAS: ANTICONVULSIVANTES, ANTIFÚNGICOS AZÓLICOS, ANTIDEPRESSIVOS. CONTRAINDICATIONS: CARDIOVASCULAR DISORDERS, DIABETES MELLITUS WITH VASCULAR DAMAGE. DRUG INTERACTIONS: ANTICONVULSANTS, AZOLE ANTIFUNGALS, ANTIDEPRESSANTS

G.WH.GT.03.2014.0053 L.BR.03.2014.1711

Breakfast Symposium

Ballroom7h00–8h00, Friday 02 May 2014

Innovation in endometriosis: perspectives from academia

& industry

Faculty: Charles Chapron (France), Oliver Martin Fischer, Bayer (Germany), Katy Vincent (UK), Thomas Zollner, Bayer (Germany)