Scrub typhus Rickettsial zoonoses

Dr.Rajeev

HISTORY

Most wide spread A/C febrile illness caused by orienta tsutsugamushi

First identified in china in 313 AD

Intacellular gram neg.org.isolated in japan in 1930

Zoonoses in nature exists in nature between mites and rodents

Geographical distribution

Mode of transmission

Mite Rat,Mice Mite Rat,Mice Man Maintained in nature transovarially in

mites Adult and nymph mites are free living Larva (chiggar) feed on man

introducing bacteria

Trombiculid mite

Adult

Larva(chigger)

Clinical features

Incubation period 6to20 days

A/C fever and chills 104-105*c Head ache, Malaise, Prostration, Macular rashes -5th day ESCHAR-punched out ulcer with central

necrosis Lymph adenitis Hepato splenomegally

Eschar

Complications

ARDS Myocarditis A/C Renal failure DIC

Diagnosis and treatment

4 fold increase in antibody titre Weil felix positive withOXK STRAIN Immuno peroxidase test Immuno flurocent test

Responds to tetracycline,doxycycline,azithromyci etc.

PREVENTIVE MEASURES

Avoid areas where there is known typhus outbreak

Avoid over crowded living conditions Spray for ticks fleas mites Practice good hygeine Care farmers working in farms,in

bushes,andthose who are close to rodents,domestic animals etc.

NO VACCINE at present

THANK U