section 1: identification of the substance/mixture and · pdf filesection 1: identification of...

SAFETY DATA SHEET

EPICHLOROHYDRIN

Revision Date 04/02/2015

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SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifier

- Trade name EPICHLOROHYDRIN- Chemical Name Epichlorohydrin- Synonyms 1-chloro-2,3-epoxypropane- Molecular formula C3H5OCl

1.2 Relevant identified uses of the substance or mixture and uses advised against

Uses of the Substance / Mixture

- Chemical intermediate

1.3 Details of the supplier of the safety data sheet

Company

SOLVAY CHEMICALS, INC.3333 RICHMOND AVENUE77098-3099, HOUSTONUSATel: +1-800-7658292; +1-713-5256800Fax: +1-713-5257804

Prepared by

Solvay Product Stewardship (see Telephone number above)

Date Prepared

04/02/2015

1.4 Emergency telephone

FOR EMERGENCIES INVOLVING A SPILL, LEAK, FIRE, EXPOSURE OR ACCIDENT CONTACT: CHEMTREC 800-424-9300 within the United States and Canada, or 703-527-3887 for international collect calls.

SECTION 2: Hazards identification

2.1 Emergency overview

Appearance

Physical state: liquidColor: colorlessOdor: pungent

Warning statements

- Flammable- May cause cancer.- Toxic by inhalation, in contact with skin and if swallowed.- Causes burns.- May cause sensitization by skin contact.- Hazardous decomposition products formed under fire conditions.

2.2 Potential Health Effects

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Inhalation effect

- May be fatal if inhaled.- irritation of the upper respiratory tract- Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting.- Risk of: Lung edema- Chemical pneumonitis- Repeated or prolonged exposure- Inhalation may cause central nervous system effects.

Skin effect

- The product may be absorbed through the skin. - May cause an allergic skin reaction. - Symptoms - Irritation - Redness - Swelling of tissue - Burn

Eye effect

- Severe eye irritation- Risk of temporary eye lesions.- Symptoms- Redness- Lachrymation

Ingestion effect

- Severe irritation- Risk of convulsions, loss of consciousness, deep coma and cardiopulmonary arrest.- Liver and kidney injuries may occur.- Symptoms- Nausea- Vomiting- Abdominal pain- Diarrhea

Chronic effects

- This product contains ingredients that are considered to be probable or suspected human carcinogens, or confirmed animal carcinogens with unknown relevance to humans (see Section 11 – Chronic).

SECTION 3: Composition/information on ingredients

3.1 Information on Components and Impurities

WHMIS Hazardous Ingredients and Impurities

Chemical NameIdentification number

CAS-No.Concentration [%]

Epichlorhydrin 106-89-8 >= 99

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SECTION 4: First aid measures

4.1 Description of first-aid measures

In case of inhalation

- In case of accident by inhalation: remove casualty to fresh air and keep at rest.- Victim to lie down in the recovery position, cover and keep him warm.- Oxygen or artificial respiration if needed.- Take victim immediately to hospital.

In case of skin contact

- Remove and wash contaminated clothing before re-use.- Wash off with soap and water.- If symptoms persist, call a physician.

In case of eye contact

- Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.- Immediate medical attention is required.

In case of ingestion

- Consult a physician.- Take victim immediately to hospital.- If swallowed, rinse mouth with water (only if the person is conscious).- Do NOT induce vomiting.- Do not give anything to drink.- Artificial respiration and/or oxygen may be necessary.

4.2 Most important symptoms and effects, both acute and delayed

In case of inhalation

Symptoms- Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and

vomiting.

Effects- May be fatal if inhaled.- irritation of the upper respiratory tract- Risk of: Lung edema- Risk of chemical pneumonitisRepeated or prolonged exposure

- Inhalation may cause central nervous system effects.

In case of skin contact

Symptoms- Irritation- Redness- Swelling of tissue- Burn

Effects- The product may be absorbed through the skin.- May cause an allergic skin reaction.

In case of eye contact

Symptoms

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- Redness- Lachrymation

Effects- Severe eye irritation- Risk of temporary eye lesions.

In case of ingestion

Symptoms- Severe irritation- Nausea- Vomiting- Abdominal pain- Diarrhea

Effects- Risk of convulsions, loss of consciousness, deep coma and cardiopulmonary arrest.- Liver and kidney injuries may occur.

4.3 Indication of any immediate medical attention and special treatment needed

Notes to physician

- In the case of difficulty of opening the lids, administer an analgesic eye wash (oxybuprocaine).- Immediate medical attention is required.- Medical examination necessary even only on suspicion of intoxication.

SECTION 5: Firefighting measures

Flash point 82 °F (28 °C)closed cup

104 °F (40 °C)open cup

Autoignition temperature 725 °F (385 °C)

Flammability / Explosive limit Lower flammability/explosion limit : 3.80 %(V)3.80 %(V)

Upper flammability/explosion limit : 21.00 %(V)21.00 %(V)

5.1 Extinguishing media

Suitable extinguishing media

- powder- Foam- Carbon dioxide (CO2)

Unsuitable extinguishing media

- Water spray jet

5.2 Special hazards arising from the substance or mixture

Specific hazards during fire fighting

- Flammable liquid and vapor.- Hazardous decomposition products formed under fire conditions.

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Hazardous combustion products:

- Hydrogen chloride gas- Phosgene- Carbon monoxide

5.3 Advice for firefighters

Special protective equipment for fire-fighters

- Wear self-contained breathing apparatus and protective suit.- Full protective flameproof clothing- Wear chemical resistant oversuit- Keep product and empty container away from heat and sources of ignition.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel

- Evacuate personnel to safe areas.- Prevent further leakage or spillage if safe to do so.

Advice for emergency responders

- Wear self-contained breathing apparatus and protective suit.- Remove all sources of ignition.- Cover the spreading liquid with foam in order to slow down the evaporation.- Ventilate the area.- Prevent further leakage or spillage if safe to do so.- Keep away from incompatible products

6.2 Environmental precautions

- Discharge into the environment must be avoided.- Do not flush into surface water or sanitary sewer system.- In case of accidental release or spill, immediately notify the appropriate authorities if required by Federal, State/Provincial

and local laws and regulations.- Discharge into the environment must be avoided.- Do not flush into surface water or sanitary sewer system.- In case of accidental release or spill, immediately notify the appropriate authorities if required by Federal, State/Provincial

and local laws and regulations.

6.3 Methods and materials for containment and cleaning up

- Dam up.- Soak up with inert absorbent material.- Prevent product from entering sewage system.- Keep in suitable, closed containers for disposal.

6.4 Reference to other sections

- Refer to protective measures listed in sections 7 and 8.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

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- Used in closed system- Use only in well-ventilated areas.- Keep away from heat and sources of ignition.- Heating can release vapors which can be ignited.- To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded.- When transferring from one container to another apply grounding measures and use conductive hose material.- Preferably transfer by pump or gravity.- Do not use sparking tools.- Keep away from incompatible products

Hygiene measures

- Ensure that eyewash stations and safety showers are close to the workstation location.- When using do not eat, drink or smoke.- Wash hands before breaks and at the end of workday.- Handle in accordance with good industrial hygiene and safety practice.

7.2 Conditions for safe storage, including any incompatibilities

Technical measures/Storage conditions

- Store in original container.- Keep container closed.- Keep in a well-ventilated place.- Keep in a contained area- Keep away from heat/sparks/open flames/hot surfaces. No smoking.- Take measures to prevent the build up of electrostatic charge.

- Keep away from:- Incompatible products

Packaging material

Suitable material- Steel drum- Stainless steel

Unsuitable material- no data available

7.3 Specific end use(s)

- Contact your supplier for additional information

SECTION 8: Exposure controls/personal protection

Introductory Remarks: These recommendations provide general guidance for handling this product. Because specific work environments and material handling practices vary, safety procedures should be developed for each intended application. Assistance with selection, use and maintenance of worker protection equipment is generally available from equipment manufacturers.

8.1 Control parameters

Components with workplace occupational exposure limits

Consult local authorities for acceptable exposure limits.

Ingredients Value type Value BasisEpichlorhydrin TWA 0.5 ppm American Conference of Governmental

Industrial Hygienists

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Upper Respiratory Tract irritation, Male reproductive, Confirmed animal carcinogen with unknown relevance to humans, Danger of cutaneous absorption

8.2 Exposure controls

Control measures

Engineering measures- Ensure adequate ventilation.- Apply technical measures to comply with the occupational exposure limits.

Individual protection measures

Respiratory protection- Self-contained breathing apparatus in confined spaces/insufficient oxygen/in case of large uncontrolled

emissions/in all circumstances when the mask and cartridge do not give adequate protection.- Use only respiratory protection that conforms to international/ national standards.- Use NIOSH approved respiratory protection.

Hand protection- Wear suitable gloves.- Take note of the information given by the producer concerning permeability and break through times, and of special

workplace conditions (mechanical strain, duration of contact).Suitable material- butyl-rubber- Fluoroelastomer

Eye protection- Chemical resistant goggles must be worn.

- If splashes are likely to occur, wear:- Goggles- Face-shield

Skin and body protection- Flame-resistant clothing- impervious clothing

Hygiene measures- Ensure that eyewash stations and safety showers are close to the workstation location.- When using do not eat, drink or smoke.- Wash hands before breaks and at the end of workday.- Handle in accordance with good industrial hygiene and safety practice.

SECTION 9: Physical and chemical properties

Physical and Chemical properties here represent typical properties of this product. Contact the business area using the Product information phone number in Section 1 for its exact specifications.

9.1 Information on basic physical and chemical properties

Appearance Physical state: liquidColor: colorless

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Odor pungent

Odor Threshold no data available

pH Not applicable

Freezing point -71 °F (-57 °C) ( 760.00 mmHg (1,013.25 hPa))

Boiling point/boiling range 243 °F (117 °C) ( 759.81 mmHg (1,013 hPa))

Flash point 82 °F (28 °C) ( 759.81 mmHg (1,013 hPa))closed cup

104 °F (40 °C) ( 759.81 mmHg (1,013 hPa))open cup

Evaporation rate (Butylacetate = 1) no data available

Flammability (solid, gas) Not applicable, liquid

Flammability / Explosive limit Lower flammability/explosion limit: 3.80 %(V)

Type: lower flammability limit3.80 %(V)

Upper flammability/explosion limit:21.00 %(V)

Type: upper flammability limit21.00 %(V)

Explosiveness:Not explosive

Autoignition temperature 725 °F (385 °C) ( 759.81 mmHg (1,013 hPa))

Vapor pressure 17.10 mmHg (22.8 hPa) ( 77 °F (25 °C))

Vapor density 3.2

Density Relative density: 1.18 ( 68 °F (20 °C))

Solubility Water solubility :65.9 g/l ( 77 °F (25 °C))

Solubility in other solvents: common organic solvents : soluble

Partition coefficient: n-octanol/water log Pow: 0.45

Thermal decomposition ca. 437 °F (225 °C)

Viscosity Viscosity, dynamic : 1.037 mPa.s ( 68 °F (20 °C))

Explosive properties Not explosiveStructure-activity relationship (SAR)

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Oxidizing properties Not considered as oxidizing., Expert statement

9.2 Other information

Surface tension 72.3 mN/m 1.01 g/l ( 70.7 °F (21.5 °C))solution

Dust explosion constant Not applicableliquid

Minimum ignition energy Not applicable, liquid

Molecular weight 92.53 g/mol

SECTION 10: Stability and reactivity

10.1 Reactivity

- May decompose on long exposure to light.- Risk of explosion.

10.2 Chemical stability

- Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

- Strong oxidizers, alkali metals and alkaline earth metals may cause fires or explosions.

10.4 Conditions to avoid

- Heat, flames and sparks.- To avoid thermal decomposition, do not overheat.- Keep away from direct sunlight.

10.5 Incompatible materials

- Oxidizing agents- Light metals- Alcohol- Amines- Alkalis

10.6 Hazardous decomposition products

- Hydrogen chloride gas- Phosgene- Carbon monoxide

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity

Acute oral toxicityToxic if swallowed.

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LD50: 282 mg/kg - Rat , malesUnpublished reports

LD50: 175 mg/kg - Rat , femalesUnpublished reports

Acute inhalation toxicityLC50 : 4,114 mg/m3 360 ppm - Rat

Acute dermal toxicityToxic in contact with skin.

LD50 : 515 mg/kg - Rat , for males and femalesUnpublished reports

Acute toxicity (other routes of administration)

no data available

Skin corrosion/irritation

RabbitCauses burns.Published data

Serious eye damage/eye irritation

RabbitCorrosivePublished data

Respiratory or skin sensitization

Maximization Test (GPMT) - Guinea pigMay cause sensitization by skin contact.Published data

Mutagenicity

Genotoxicity in vitroIn vitro tests showed mutagenic effectsUnpublished reportsPublished data

Genotoxicity in vivoIn vivo tests showed mutagenic effectsPublished data

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Carcinogenicity

RatOralExposure time: Prolonged exposureLOAEL: 2mg/kgTarget Organs: StomachMethod: OECD Test Guideline 451Published data

RatInhalationExposure time: Prolonged exposureLOAEC: 113mg/m³Target Organs: Nasal inner liningPublished data

Ingredients CAS-No. Rating Basis

Epichlorhydrin 106-89-8 Group 2A: Probably carcinogenic to humans

IARC

Epichlorhydrin 106-89-8 Confirmed animal carcinogen with unknown relevance to humans

ACGIH

Toxicity for reproduction and development

Toxicity to reproduction / fertilityPossible risk of impaired fertility.

Rat , for males and femalesOral exposureLOAEL parent: 12.5 mg/kgPublished data

Rat , for males and femalesInhalationTest substance: VaporNo effect observed on developmentno teratogenic effects have been observedUnpublished reports

Rabbit , for males and femalesInhalationTest substance: VaporNo effect observed on developmentno teratogenic effects have been observedUnpublished reports

Developmental Toxicity/Teratogenicity no data available

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STOT

STOT-single exposureMay cause respiratory irritation.

STOT-repeated exposureThe substance or mixture is not classified as specific target organ toxicant, repeated exposure.

Oral - Rat , for males and femalesNOAEL: 1 mg / kg / dayTarget Organs: StomachGavagePublished data

Inhalation - Rat , for males and femalesNOAEL: 18.9 mg/m³Published data

Inhalation - Mouse , for males and femalesNOAEL: 18.9 mg/m³Published data

Aspiration toxicity no data available

SECTION 12: Ecological information

12.1 Toxicity

Aquatic Compartment

Acute toxicity to fish LC50 - 96 h : 10.6 mg/l - Pimephales promelas (fathead minnow)Unpublished reportsPublished data

Acute toxicity to daphnia and other aquatic invertebrates.EC50 - 48 h : 23.9 mg/l - Daphnia magna (Water flea)Unpublished reportsPublished data

Toxicity to aquatic plantsEC50 - 72 h : 15 mg/l - Pseudokirchneriella subcapitata (green algae)Growth rateUnpublished reports

Toxicity to microorganismsNOEC - 16 h : 27.5 mg/l - Pseudomonas putidaPublished data

12.2 Persistence and degradability

Abiotic degradation

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Stability in waterHalf-life value: 7.3 d (68 °F (20 °C))pH: 4.0Unpublished reports, Half-life value: 3.9 d (68 °F (20 °C))pH: 7.0Unpublished reports, Half-life value: 6.8 d (68 °F (20 °C))pH: 9.0Unpublished reports,

Photodegradationindirect photo-oxidationHalf-life (direct photolysis): 36.5 DaysAir

Biodegradation

BiodegradabilityUltimate aerobic biodegradabilityMethod: OECD Test Guideline 301ca. 18 % - 14 dNot readily biodegradable.Published data

Ultimate aerobic biodegradabilityMethod: OECD Test Guideline 30192.5 % - 14 dReadily biodegradable.Published data

Method: Simulation study

Method: Degradation in sewage treatment plants98 % - 2 hUnpublished reports

12.3 Bioaccumulative potential

Partition coefficient: n-octanol/waterNot potentially bioaccumulablePublished data

Bioconcentration factor (BCF)Does not bioaccumulate.

12.4 Mobility in soil

Adsorption potential (Koc)WaterThe product evaporates slowly.

AirHydrolyzis

Soilconsiderable percolation

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12.5 Results of PBT and vPvB assessment no data available

12.6 Other adverse effects no data available

Ecotoxicity assessment

Acute aquatic toxicityHarmful to aquatic organisms.

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product Disposal

- Refer to manufacturer/supplier for information on recovery/recycling.- The organic ingredients can be incinerated in a suitable installation when in accordance with local regulations.- In accordance with local and national regulations.

Advice on cleaning and disposal of packaging

- If recycling is not practicable, dispose of in compliance with local regulations.- Dispose of as unused product.

SECTION 14: Transport information

Transportation status: IMPORTANT! Statements below provide additional data on listed transport classification.The listed Transportation Classification does not address regulatory variations due to changes in package size, mode of shipment or other regulatory descriptors.

TDG

14.1 UN number UN 2023

14.2 Proper shipping name EPICHLOROHYDRIN

14.3 Transport hazard class 6.1Subsidiary hazard class 3Label(s) 6.1 (3)

14.4 Packing groupPacking group IIERG No 131P

14.5 Environmental hazardsMarine pollutant

YES

DOT



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14.4 Packing groupPacking group IIERG No 131P


YES

14.6 Special precautions for user

This product contains one or more ingredients identified as a hazardous substance in Appendix A of 49 CFR 172.101. The product quantity, in one package, which triggers the RQ requirements under 49 CFR for each hazardous substance is shown.

Reportable quantities : RQ substance: EpichlorhydrinRQ limit for substance: 100 lbRQ limit for product: 100 lb

NOMno data available

IMDG




14.4 Packing groupPacking group II


NO

14.6 Special precautions for userEmS F-E , S-D

For personal protection see section 8.

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IATA



14.3 Transport hazard class 6.1 Subsidiary hazard class: 3Label(s): 6.1 (3)

14.4 Packing groupPacking group II

Packing instruction (cargo aircraft) 662Max net qty / pkg 60.00 LPacking instruction (passenger aircraft) 654Max net qty / pkg 5.00 L

14.5 Environmental hazards YES

14.6 Special precautions for userFor personal protection see section 8.

Note: The above regulatory prescriptions are those valid on the date of publication of this sheet. Given the possible evolution of transportation regulations for hazardous materials, it would be advisable to check their validity with your sales office.

SECTION 15: Regulatory information

15.1Notification status

Inventory Information StatusUnited States TSCA Inventory Listed on Inventory

Mexico INSQ (INSQ) In compliance with the inventory

Canadian Domestic Substances List (DSL) Listed on Inventory

New Zealand. Inventory of Chemical Substances In compliance with the inventory

Australia Inventory of Chemical Substances (AICS) Listed on Inventory

Japan. CSCL - Inventory of Existing and New Chemical Substances Listed on Inventory

Korea. Korean Existing Chemicals Inventory (KECI) Listed on Inventory

China. Inventory of Existing Chemical Substances in China (IECSC) Listed on Inventory

Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed on Inventory

15.2 WHMIS (Workplace Hazardous Materials Information System) Classification

This product has been classified according to the hazard criteria of the CPR and the MSDS contains all of the information required by the CPR.

Classification B2: Flammable Liquid

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D1A:Very Toxic Material Causing Immediate and Serious Toxic EffectsD2A:Very Toxic Material Causing Other Toxic EffectsE:Corrosive MaterialContains a controlled product

15.3 Other regulations

no data available

SECTION 16: Other information

NFPA (National Fire Protection Association) - Classification

Health 3 seriousFlammability 3 seriousInstability or Reactivity 2 moderateSpecial Notices None

HMIS (Hazardous Materials Identification System (Paint & Coating)) - Classification

Health 3 seriousFlammability 3 seriousReactivity 2 moderatePPE Determined by User; dependent on local conditions

Key or legend to abbreviations and acronyms used in the safety data sheet

- TWA 8-hour, time-weighted average- ACGIH American Conference of Governmental Industrial Hygienists- OSHA Occupational Safety and Health Administration- NTP National Toxicology Program- IARC International Agency for Research on Cancer- NIOSH National Institute for Occupational Safety and Health

The information provided in this Safety Data Sheet is correct to the best of our knowledge, information, and belief at the date of its publication. Such information is only given as a guidance to help the user handle, use, process, store, transport, dispose, and release the product in satisfactory safety conditions and is not to be considered as a warranty or quality specification. It should be used in conjunction with technical sheets but do not replace them. Thus, the information only relates to the designated specific product and may not be applicable if such product is used in combination with other materials or in another manufacturing process, unless otherwise specifically indicated. It does not release the user from ensuring he is in conformity with all regulations linked to its activity.

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