šegradska 26/ii fax: +381-11-3611-261 shool of …mfub.bg.ac.rs/dotasset/70526.pdf · ·...

Institute of Medical physiology Višegradska 26/II 11 000 Belgrade telephone: +381-11-3607-093 fax: +381-11-3611-261

SHOOL OF MEDICINE UNIVERSITY OF BELGRADE PROGRAMME OF LECTURES IN MEDICAL PHYSIOLOGY

Summer (IV) semester 2013 – 2014 academic year Lectures will held in the Library at the Institute of Medical physiology on: Monday and Tuesday from 08:30 to 10:00 AM for both groups (I and II)

HEART PHYSIOLOGY February 18 8 hrs Dr Sanja Mazić, Assistant professor February 22 PHYSIOLOGY OF THE CIRCULATION February 24 8 hrs Dr Dragan Đurić, Full Professor February 25 March 03 March 04 BLOOD PHYSIOLOGY March 10 8 hrs Dr Aleksandra Rašić - Marković, Assistant professor March 11 March 17 March 18 KIDNEY PHYSIOLOGY March 24 6 hrs Dr Zvezdana Kojić, Full professor March 25 March 31 RESPIRATORY PHYSIOLOGY April 01 8 hrs Dr Dušan Mitrović, Full Professor April 07 April 08 April 14 ACID – BASE BALANCE April 15 2 hrs Dr Dušan Mitrović, Full Professor PHYSIOLOGY OF THE GASTROINTESTINAL SYSTEM April 21(make up)6 hrs Dr Ljiljana Šćepanović, Full professor April 22 April 28 ENERGETICS AND METABOLISM April 29 4 hrs Dr Slavica Suzić, Full Professor May 05 PHYSIOLOGY OF NUTRITION May 06 2 hrs Dr Slavica Suzić, Full Professor THERMOREGULATION May 12 2 hrs Dr Slavica Suzić, Full Professor


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INTRODUCTION TO ENDOCRINOLOGY AND NEUROENDOCRINE INTEGRATION: HYPOTHALAMIC-HYPOPHYSIAL SYSTEM May 13 2 hrs Dr Salvica Suzić, Full professor PHYSIOLOGY OF ENDOCRINE GLANDS May 19 8 hrs Dr Dejan Nešić, Assistant professor May 20

May 26 May 27 PHYSIOLOGY OF REPRODUCTIVE SYSTEM June 02 4 hrs Dr Sanja Mazić, Assistant professor June 03

INSTITUTE OF MEDICAL PHYSIOLOGY


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SHOOL OF MEDICINE UNIVERSITY OF BELGRADE PROGRAMME OF EXERCISES IN MEDICAL PHYSIOLOGY

IV (summer) semester 2013 – 2014 academic year Exercise XIV (4 hours), February 24 - 25, 2014; dr Jovana Jakovljević, Teaching Assistant; 1. Palpation of arterial pulse oscillations on various sites of the body 2. Estimation of radial artery pulse qualities in humans 3. Recording and analysis of arterial pulse oscillations (sphygmogram) 4. Measurement of velocity of fluid flow (ml/min) on the various models of piezometer 5. Video presentation of vascular system (A.D.A.M.) 6. Principles of hemodynamics (PhysioEx 4.0): Measurement of blood flow (ml/min) under

condition of changes in the blood vessel radius, viscosity of blood, length of the blood vessel and pressure gradient

SEMINAR 12: Cardiac cycle: variations in different physiological conditions. Cardiac output and cardiac output regulation (2 hours). Exercise XV (4 hours), March 03 – 04, 2014; dr Igor Pantić, Teaching Assistant; 1. Measurement of arterial blood pressure using palpatory and auscultatory methods in

human 2. Demonstration of the effects of hydrostatic pressure and the role of venous valves on

venous blood flow 3. Assessment of functional capacity of the heart and circulation during physical activity in

human (Lorentz and Harvard step tests) 4. Explanation of oculocardiac reflex 5. Interactive presentation of the experiment: the direct measurement of arterial blood

pressure and influence of vasopressor and vasodepressor agents on the value of arterial blood pressure (Dog Blood Pressure)

6. Interactive videosimulation of the effects of vasoactive substances on the isolated blood vessel (SimVessel)

SEMINAR 13: Regulation of arterial blood pressure (2 hours) Exercise XVI (4 hours), March 10 – 11, 2014; dr Marina Đelić, Teaching Assistant; 1. Obtaining of blood samples for laboratory analysis from the finger tip 2. Preparation and staining of the blood smear by Pappenheim's method 3. Identification of blood cells 4. Determination of reticulocyte count staining a slide using brilliant cresyl blue stain 5. Determination of erythrocyte sedimentation rate (ESR)


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Exercise XVII (4 hours), March 17 – 18, 2014; dr Igor Pantić, Teaching Assistant; 1. Determination of red blood cell count by haemocytometer and erythrocyte suspension

optical density 2. Hematocrit (Htc) or Packed Cell Volume (PCV) determination (microhematocrit method) 3. Hemoglobin determination 4. Calculation of the mean corpuscular values (MCV, MCH, MCHC) using the former

obtained values Exercise XVIII (4 hours), March 24 – 25, 2014; dr Marina Đelić, Teaching Assistant; 1. OAB blood typing on the slide and in test tubes 2. Rh typing (RhD) 3. Performing of cross matching reaction and direct Coombs' test SEMINAR 14: Blood groups (OAB, Rh system), transfusion and transfusional reactions (2 hours) Exercise XIX (4 hours), March 31 - April 01, 2014; dr Dragan Hrnčić, Teaching Assistant; 1. Determination of white blood cell count 2. Determination of differential white blood cell count 3. Calculation of absolute white blood cell count 4. Interactive video presentation of homeostasis of body electrolytes (A.D.A.M.) – repetition Exercise XX (4 hours), April 07 – 08, 2014; dr Jovana Jakovljević, Teaching Assistant; 1. Determination of platelet count by Fonio (indirect method) 2. Determination of platelet count by hemocytometer method 3. Determination of bleeding time – Duke's method 4. Determination of blood coagulation time – Bürker method 5. Determination of prothrombin time (PT) Colloquium II: 9. Motor neurophysiology; 10. Autonomic nervous system; 11. Higher brain function; 12. Physiology of heart; 13. Physiology of the circulation; 14. Blood physiology; Exercise XXI (4 hours), April 14 – 15, 2014; dr Marija Stojanović, Teaching Assistant; 1. Calculation of the clearance of inulin, creatinine and para-aminohippuric (PAH) acid 2. Calculation of GFR in dependence on changed values of renal blood flow (RBF),

hydrostatic pressure (HP) and colloid-osmotic pressure (COP) 3. Calculation of diuresis in dependence on osmotic load of the kidneys (osmolar clearance

and “free water clearance” 4. Interactive video simulation of function of the nephron (PhysioEx 4.0): studying the effect

of factors that affect glomerular filtration rate, volume and osmolality of final urine 5. Interactive video presentation of functions of the urinary tract (A.D.A.M.)


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SEMINAR 15: Renal regulation of extracellular fluid volume and composition. Hormones of the kidney. (2 hours). Exercise XXII (4 hours), Make up April 21, 2014; April 22, 2014; dr Jovana Jakovljević, Teaching Assistant; 1. Demonstration of the role of the diaphragm in respiration (Donders' model) 2. Spirometry: determination of the static lung volumes and capacities 3. Performing of the ergometric step-test and indirect determination of the maximal oxygen

consumption (VO2max) SEMINAR 16: Chemistry in Medical Physiology: Acid-base balance. Body chemical buffers (2 hours) Exercise XXIII (4 hours), April 28 – 29, 2014; dr Igor Pantić, Teaching Assistant; 1. Auscultation of breathing 2. Interactive video simulation of alveolar ventilation (PhysioEx 4.0):

a. measuring respiratory volumes and capacities (simulating spirometry) b. examining the effect of changing airway resistance, the action of surfactant and the

effect of changing intrapleural pressure on the lung functions c. analysis of the effect of various breathing patterns on PCO2 values in the alveolar air and

blood 3. Interactive video presentation of functions of the respiratory system (A.D.A.M.) SEMINAR 17: Regulation of respiration (2 hours). Exercise XXIV (4 hours), May 05 – 06, 2014; dr Dragan Hrnčić, Teaching Assistant; 1. Spirometry: measuring dynamic lung volumes: FEV1, the maximal voluntary ventilation

(MVV), and recording of the flow-volume curve 2. Cardiopulmonary resuscitation: basic principles of performing CPR by various methods

(practicing on a model) 3. Interactive video presentation of acid-base balance (A.D.A.M.) 4. Acid-base balance – computer simulation (PhysioEx 4.0): demonstration of buffering

action of the lung and the kidney in acid-base homeostasis (compensation of acidosis and alkalosis)

SEMINAR 18: Role of the hypothalamus in the control of homeostatic control systems of the body (2 hours) Colloquium III: 15. Renal physiology, 16. Respiratory physiology; 17. Acid-base balance; 18. Physiology of the gastrointestinal system 19. Energy balance and metabolism; 20. Physiology of nutrition;


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Exercise XXV (4 hours), May 12 – 13, 2014; dr Marija Stojanović, Teaching Assistant; 1. Calculation of the basal metabolic rate (BMR) for students 2. Calculation of the daily energy turnover in students 3. Assembling of the nutritious meal on the basis of the determined turnover of the energy 4. Interactive video session of the gastric antrum contractile response(SimVessel):

demonstration of the effects of substances that affect the spontaneous activity and the effect of passive stretching

5. Interactive video presentation of gastrointestinal system (A.D.A.M.) SEMINAR 19: Physiology of the liver. Endocrine function of gastrointestinal system (2 hours) Exercise XXVI (4 hours), May 19 – 20, 2014; dr Dragan Hrnčić, Teaching Assistant; 1. Assessment of the oral glucose tolerance test (OGTT) 2. Interactive video simulation of the endocrine system physiology (PhysioEx 4.0):

a. determination of rat’s basal metabolic rate and demonstration of the effects of thyroxine, TSH and propylthiouracil on the rat’s basal metabolic rate

b. demonstration of the effect of estrogen on the morphological and functional characteristics of the uterus

c. measurement of plasma glucose concentration using spectrophotocolorimetric method and demonstration of the effect of insulin on glucose concentration in the blood

3. VIRTUAL PATIENT: assessment of disturbed homeostatic variables in (“SimBioSys Physiology”)

SEMINAR 20: Homeostasis of calcium and magnesium; bone physiology (2 hours) Exercise XXVII (4 hours), May 26 – 27, 2014; dr Marina Đelić, Teaching Assistant; 1. Examination of vaginal smear cytological features in the time course of menstrual cycle 2. Early diagnosis of the pregnancy: laboratory tests a. Analysis of the blood cells (number of cell types, ESR, and mean corpuscular values) in

a.physiological conditions 3. Analysis of the plasma composition in physiological conditions 4. Analysis of the urine composition in physiological conditions 5. Signitures, makeup of exercises and seminars SEMINAR 20: Life cycles of female reproductive system

INSTITUTE OF MEDICAL PHYSIOLOGY


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CCoollllooqquuiiuumm IIII

Colloquium II will be held on Tuesday, April 8, 2014 at 2:00 PM in the classroom on the Institute of Medical physiology for the first and the second group

Make up of Colloquium II will be held on Tuesday, April, 2014 at 2:00 PM in the classroom on the Institute of Medical physiology for the first and the second group

Colloquium II: 9. Motor neurophysiology; 10. Autonomic nervous system; 11. Higher brain function; 12. Physiology of heart; 13. Physiology of the circulation; 14. Blood physiology;


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CCoollllooqquuiiuumm IIIIII

Colloquium III will be held on Tuesday, May 6, 2014 at 2:00 PM in the classroom on the Institute of Medical physiology for the first and the second group

Make up of Colloquium III will be held on Tuesday, May 13, 2014 at 2:00 PM in the classroom on the Institute of Medical physiology for the first and the second group

Colloquium III: 15. Renal physiology, 16. Respiratory physiology; 17. Acid-base balance; 18. Physiology of the gastrointestinal system 19. Energy balance and metabolism; 20. Physiology of nutrition;


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GRADING POLICY – Components and Evaluation Method in Assessment of Medical Physiology According to Declaration of Bologna

Regular Attendance in Course in Medical Physiology (maximum 6 points): 1. Regular attendance at lectures 2. Regular attendance at practicals 3. Regular attendance at class discussion

2 points 2 points 2 points

Colloquia – maximum 24 points for 4 colloquia

(Each colloqium in Medical Physiology from 2 to 6 points in accordance with marks from 6 to 10; makeup of colloquim decrease acquired points for 1 point)

Number of correct answers Mark Points > 18 5 0

18-21 6 2 22-24 7 3 25-28 8 4 29-31 9 5 31-35 10 6

Practical Exam Score (two tasks) (maximum 20 points)

(Mark and number of points are determined by Professor, Teaching Assistant mark is descriptive)

Final Exam Score (number of correct answers, mark and points) (Part One and Part Two maximum 50 points)

(51 – 64 ) 6 30 points (65 – 76) 7 36 points (77 – 86) 8 40 points (87 - 94) 9 44 points

(95 – 100) 10 50 points

Final course grade based upon total points Total Points from Regular Attendance, Colloquia, Practical exam, and Final Exam

5 (fail; F) > 50 points 6 (sufficient; D; D+; D-) 51 – 60 points 7 (satisfactory; C; C+; C-) 61 – 70 points 8 (good; B; B-) 71 – 80 points 9 (very good; A; A-; B+) 81 – 90 points 10 (excellent; A+) 91 – 100 points


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In order to finish the Medical Physiology Course successfully, students should pay attention to the following: Ø Physiology requires total dedication. Ø Read before each lecture. Ø Take you seminars seriously! Ø Attend all lectures.

Ø Visit the website regularly. Ø By all means don’t fall behind in your studies. Ø Visit your professors and chairperson when

necessary.

Course Director Prof. dr Tomislav Jovanović

[email protected]

šegradska 26/ii fax: +381-11-3611-261 shool of …mfub.bg.ac.rs/dotasset/70526.pdf · ·...

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