selective rearing visual cortex and beyond

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1 9/26/11 1 Visual cortex and beyond Chapter 4 Selective rearing 9/26/11 2 9/26/11 3 Retina Subcortical Structures White Matter Optic Nerve - Optic Chiasm Cortex Where do retinal signals go? 9/26/11 4 Primary visual area (V1) Medial view Lateral view

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Page 1: Selective rearing Visual cortex and beyond

1

9/26/11 1

Visual cortex and beyond

Chapter 4

Selective rearing

9/26/11 2

9/26/11 3

Retina

Subcortical Structures

White Matter

Optic Nerve - Optic Chiasm

Cortex

Where do retinal signals go?

9/26/11 4

Primary visual area (V1)

Medial view

Lateral view

Page 2: Selective rearing Visual cortex and beyond

2

9/26/11 5

MRI / fMRI

MRI - structural or anatomical images fMRI - functional images (measure neural activity)

9/26/11 6

Visual cortex activation

A

B

C

C

A

B

9/26/11 7

Retinotopic mapping

9/26/11 8

Retinotopic organization

•  Adjacent locations in space are coded by adjacent sets of neurons (continuity)

Center of gaze

Periphery

RH

Stimulus

Page 3: Selective rearing Visual cortex and beyond

3

Cortical maps are distorted

9/26/11 9 9/26/11 10

Cortical maps are distorted

Visual stimulus Cortical activation

Center of gaze

Periphery

Visual system organization

•  Retinotopic maps in LGN & visual cortex

•  Cortical maps are distorted (cortical magnification factor)

9/26/11 11 9/26/11 12

Page 4: Selective rearing Visual cortex and beyond

4

9/26/11 13

Visual system organization

•  Retinotopic maps in LGN & visual cortex

•  Cortical maps are distorted (cortical magnification factor)

•  Columnar organization –  Location columns – Orientation columns – Ocular dominance columns

9/26/11 14

Hypercolumns

9/26/11 15 9/26/11 16

Page 5: Selective rearing Visual cortex and beyond

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9/26/11 17

Lesioning or ablation experiments

Used by Ungerleider & Mishkin to show ‘What & Where pathways’

9/26/11 18

9/26/11 19

Where / How

What

9/26/11 20

What & how pathways - neuropsychological evidence

•  Behavior of patient D.F. (CO poisoning)

•  Other patients show opposite effects

•  Double dissociation

Page 6: Selective rearing Visual cortex and beyond

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Patient DF Control Ss

9/26/11 21

Visual system organization

•  Retinotopic maps in LGN & visual cortex

•  Cortical maps are distorted (cortical magnification factor)

•  Columnar organization –  Location columns – Orientation columns – Ocular dominance columns

•  Processing streams

9/26/11 22

Modularity

9/26/11 23 9/26/11 24

Page 7: Selective rearing Visual cortex and beyond

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9/26/11 25

Visual system organization

•  Retinotopic maps in LGN & visual cortex •  Cortical maps are distorted

(cortical magnification factor)

•  Columnar organization –  Location columns – Orientation columns – Ocular dominance columns

•  Processing streams •  Modularity

9/26/11 26