Seminar Series Week Commencing 8 August 2016 

Name of Presenter Title of Presentation Date Time Venue Further information

Seminar Series

Professor Xu Dong Zhang Regulation of PD-L1 expression in cancer cells

8 Aug 16 10:00am – 11:00am

ECU Joondalup Campus Room 31.447

CLICK MAP

CLICK FLYER ECU Research & Innovation Seminar Series Contact: Caroline Chapman c.chapman@ecu.edu.au

Associate Professor Kevin Pfleger

NHMRC Structural Review Forum 8 Aug 16 1:00pm Harry Perkins Institute McCusker Auditorium

CLICK MAP

Contact: Kevin Pfleger kevin.pfleger@perkins.uwa.edu.au

Professor Chris Reid Clinical Registries – Research data collection to facilitate evidence based practice

8 Aug 16 1:00pm – 2:00pm

St John of God Subiaco Hospital, Conference Centre, Level 3 Conference Auditorium 12 Salvado Road Subiaco

CLICK FLYER Research and Ethics Education Program Seminar Series Contact: Catherine May Catherine.May@sjog.org.au 08 9382 6213

Professor David Wishart Why NMR Matters in Metabolomics 8 Aug 16 3:00pm – 4:00pm

UWA Nedlands Campus Arts Lecture Room 5 Ground Floor, G61, Arts Building

CLICK MAP

CLICK FLYER CMCA Seminar Series Contact: Liz Albert Liz.albert@uwa.edu.au

Professor Peter Lovibond UNSW

Associative learning in Humans: Implications for cognitive architecture

8 Aug 16 5:00pm – 6:00pm

UWA Nedlands Campus Bayliss Lecture Theatre G.33

CLICK MAP

http://events.uwa.edu.au/event/20160711T033026Z-1953-11261@events.uwa.edu.au/whatson/Faculty%20of%20Science

Bayliss Seminar Series Contact: admin-scb@uwa.edu.au

Professor Bo Fernhall and Dr Tracy Baynard Both from the University of Illinois at Chicago (College of Applied Health Sciences, and the Department of Kinesiology and Nutrition)

Two lectures of 20 mins each "Inflammation, Vascular Function and Exercise" (Prof Fernhall) and "Exercise and Autonomic Function on Obesity and Diabetes" (Dr Baynard)

9 Aug 16 11:00am UWA Nedlands Campus Robin Gray Lecture Theatre, School of Sports Science, Exercise and Health 1st Floor, Parkway Entrance number 3

UWA School of Sport Science, Exercise and Health Seminar Series Contact: Barb Maslen barbara.maslen@uwa.edu.au

Susan Peters Did advancements in quantitative exposure assessments improve risk estimates in occupational studies?

9 Aug 16 11:00am – 12:00noon

UWA Nedlands Campus (corner Clifton St and Stirling Hwy - Entrance off Clifton Street) Seminar Room 5, School of Population Health

CLICK MAP

UWA School of Population Seminar Series Contact: Chloe Thomson chloe.thompson@uwa.edu.au

Juliana Hamzah, NHMRC-NHF Career Development Fellow Harry Perkins Institute of Medical Research

Novel therapy by selective degradation of abnormal extracellular matrix

9 Aug 16 1:00pm – 1:45pm

UWA Nedlands Campus School of Anatomy, Physiology & Human Biology

CLICK FLYER School of Anatomy, Physiology & Human Biology Seminar Series Contact: Debbie Hull & Helen Dooley Phone 6488 3313

Seminar Series Week Commencing 8 August 2016 

Name of Presenter Title of Presentation Date Time Venue Further information

Seminar Series

Room 1.81, 1st Floor, Anatomy Building North Off Hackett Entrance No 2

CLICK MAP

deborah.hull@uwa.edu.au or kirsty.herbert@uwa.edu.au

Matthew A. Perugini, Department of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne

Multi-Valent Inhibition of a Tetrameric Antibiotic Target

9 Aug 16 1:00pm – 2:00pm

UWA Nedlands Campus Bayliss Lecture Theatre G.33

CLICK MAP

http://events.uwa.edu.au/event/20160712T062914Z-2001-10873@events.uwa.edu.au/whatson/School%20of%20Chemistry%20and%20Biochemistry%20Seminars

Bayliss Seminar Series Contact: admin-scb@uwa.edu.au

Dr David Whyatt And Shelley Cheetham

Carbohydrate metabolism genetics: implications for chronic disease prevention in Aboriginal communities. Cochrane Systematic Review in progress entitled “Education and training for preventing sharps injuries and splash exposures in healthcare workers.

10 Aug 16 12:00noon – 1:30pm

UWA Nedlands Campus, N block QEII Medical Centre Kimberley / Pilbara room

School of Primary Aboriginal, Rural and Health Care Seminar Series Contact: Fiona Lee fiona.lee@uwa.edu.au

Dr Allan Kermode Neurology of Vision Sponsor : Allergan

10 Aug 16 5:30pm Light refresh-ments 6:00pm Seminar starts

Harry Perkins Institute Nedlands Ground Floor, Meeting Room G24

CLICK MAP

Lions Eye Institute “Colloquium” Seminar Series Contact: Jade Knapp jadeknapp@lei.org.au

Dr Jennifer Rodger NHMRC Senior Research Fellow School of Animal Biology, UWA

Brian stimulation in animal models: is it worth the effort?

11 Aug 16 12:00noon – 1:00pm

Harry Perkins Institute Nedlands Ground Floor, McCusker Auditorium

CLICK MAP

CLICK FLYER

Perkins Seminar Series Contact: Fiona Mackenzie fiona.mackenzie@perkins.uwa.edu.au

Associate Professor Livia S Carvalho

A unique inherited blinding disorder caused by mutations in a voltage-gated potassium channel This quarterly meeting is intended to provide new opportunities for scientists and clinicians to share their most novel and important findings. The Lions Eye Institute has a unique clinical interface that I hope will be further exploited, and these meetings are a great way to commence and/or strengthen interactions within the Institute.

12 Aug 16 7:00am Light refresh-ments 7:30am Seminar starts

Harry Perkins Institute Nedlands Level 1, Lotterywest Resource Room

CLICK MAP

Lions Eye Institute “Research / Clinic Quarterly Breakfast Meeting” Seminar Series Contact: Jade Knapp jadeknapp@lei.org.au

Seminar Series Week Commencing 8 August 2016 

Name of Presenter Title of Presentation Date Time Venue Further information

Seminar Series

ARE Postgraduate Students Proposals: Ken Wallace, ARE PhD Candidate

Category Errors in Natural Resource Management Planning – Issues and Solutions

12 Aug 16

11:00am – 12:00noon

UWA Nedlands Campus Agriculture Lecture Theatre, G013, North Wing Agriculture Building

CLICK MAP

http://events.uwa.edu.au/event/20160729T065404Z-1617-11078@events.uwa.edu.au/whatson/ARE

UWA, School of Agriculture and Resource Economics Seminar Series Contact: Seminar Information deborah.swindells@uwa.edu.au Seminar Coordinator maksym.polyakov@uwa.edu.au

Professor Ursula Kees: CLCRF Chair in Children’s Leukaemia; Head, Children’s Leukaemia and Cancer Division

Personalised medicine for patients with cancer

12 Aug 16 12:00noon Telethon Kids Institute 100 Roberts Road Subiaco Institute Seminar Room

CLICK MAP

CLICK FLYER

Telethon Kids Research Seminar Series Contact: Marina Stubbs Marina.Stubbs@telethonkids.org.au

Professor Sebastian Amigorena Director of Immunity and Cancer, Institut Curie, Paris

Antigen cross presentation by dendritic cells

12 Aug 16 12:00noon – 1:00pm

Harry Perkins Institute Nedlands McCusker Auditorium

CLICK MAP

CLICK FLYER

NCARD Seminar Series Contact: Tracy Hayward Tracy.hayward@uwa.edu.au

Associate Professor Sue Skull Scientific Writing 12 Aug 16 12:30pm – 1:30pm

Princess Margaret Hospital, MacDonald Lecture Theatre, Ground Floor, Administration Building or at a Hosted Video conference site or online

CLICK MAP

http://www.wahtn.org/events/seminar-scientific-writing/

WAHTN Seminar Series Contact: Sue Skull Sue.skull@uwa.edu.au

Mr Aaron Jenkins Water Sanitation and Hygiene after tropical cyclone Winston in Fiji

12 Aug 16 3:30pm ECU Campus Joondalup Building 19 Room 143

CLICK MAP

School of Science Seminar Series Contact: Yvonne Garwood y.garwood@ecu.edu.au or Lisa Skepper l.skepper@ecu.edu.au

Professor David Broadhurst School of Science ECU

Population Stratification using Personalised Metabolite Trajectories. A Case Study: Metabolomic Changes in Maternal Plasma and Urine During Normal Pregnancy

12 Aug 16 3:00pm ECU Campus Joondalup Lecture Theatre 7.102

CLICK MAP

CLICK FLYER

ECU Research & Innovation Seminar Series Contact: Caroline Chapman c.chapman@ecu.edu.au

UPCOMING SEMINARS

Name of Presenter Title of Presentation Date Time Venue Further information

Seminar Series

Lions Eye Institute Seeing Eye to Eye Some of the doctors and their area of expertise include: Prof David Mackey - Hereditary and genetic eye diseases Prof Bill Morgan - Glaucoma A/Prof Mei-Ling Tay-Kearney - Ocular infections and inflammation Dr Fred Chen - Retinal diseases

17 Aug 16 5:30pm – 8:00pm

Harry Perkins Institute Nedlands McCusker Auditorium RSVP at http://www.eventbrite.com/e/seeing-eye-to-eye-tickets-26717611094

CLICK MAP

More information can be found at: http://www.scienceweek.net.au/events/

Lions Eye Seminar Series Contact: Livia Carvalho or Seyhan Yazar liviacarvalho@lei.org.au or seyhanyazar@lei.org.au

Seminar Series Week Commencing 8 August 2016 

Name of Presenter Title of Presentation Date Time Venue Further information

Seminar Series

Combined Biological Sciences Meeting

Promoting biological science in Western Australia by encouraging the interaction of scientists, students and industry from all of the life sciences

26 Aug 16 8:00am – 5:30pm

The University Club of WA. Register at www.cbsmwa.org.au/registration Early Bird prices until COB 1 Aug

2016 Combined Biological Sciences Meeting Contact: cbsm@cbsmwa.org.au

2016 Perth HealthHack An event that brings together medical researchers and health practitioners with software creators to prototype a new generation of health products

23 Oct – 25 Oct 16

See Further Information

Curtin University Bentley Applied Chemistry Building 500 Kent St Bentley

http://old.healthhack.com.au

CLICK FLYER

Contact: David Colls Diana Adorno

Dr Melanie Barwick and Tamika Heiden

Scientist Knowledge Translation Training Workshop

27 Oct – 28 Oct 16

9:00am – 5:00pm

The University Club of WA Cost: $100 Register: https://www.trybooking.com/MJIE

http://www.wahtn.org/events/scientist-knowledge-translation-training-workshop

WAHTN Seminar Series Contact: info@wahtn.org

 

Po

ol

Gra

nd Boule

vard

Kendrew Crescent

Joondalup Drive

University Drive

Deakin R

d

Lakeside D

rive

Cornell

Parade

Chancellor Pass

Forum

WasteCompound

Police Academy

West Coast Institute of Training

TrainStation

Main EntryCourts

Sports Field

ECU Joondalup

Pines

19

17

16109

8

8a

7

1

2

32

6

4

5

30

3123 18

27

40

24

25

22

26

21

20

12

R

16a

18a

31a

17i

RARA

R

17j-l

17a-h

33b,c

33g,hP19

P13

P01

P18

P20

P02

P02

P07

P08

P06

P05

P04

P10

P09

P03

P14

P15

P11 P

12

Vario Parking

Ngoolark 34

BASEMENT

P15

P05

BASEMENT

Edith Cowan UniversityJoondalup

A B C D E F G H

1

2

3

4

5

6

7

8

Link Bridges

Accessible Parking

Reserved Parking

Staff Parking

Student Parking

University Vehicles

Visitor Parking

Accessible Route

Accessible Parking

Accessible Toilet

ATM

Book Shop

Bus Stop

Food & Beverage

Information

Medical Centre

Motorcycle Parking

Parents Room

Point of Interest

Public Phone

Retail

Security Phone

Student Print Services

Tavern

Taxi

Water Refill Station

Using ECU Room Numbers:

10 . 1 2 3

LevelBuilding Room

Po

ol

Gra

nd Boule

vard

Kendrew Crescent

Joondalup Drive

University Drive

Deakin R

d

Lakeside D

rive

Cornell

Parade

Chancellor Pass

Forum

WasteCompound

Police Academy

West Coast Institute of Training

TrainStation

Main EntryCourts

Sports Field

ECU Joondalup

Pines

19

17

16109

8

8a

7

1

2

32

6

4

5

30

3123 18

27

40

24

25

22

26

21

20

12

R

16a

18a

31a

17i

RARA

R

17j-l

17a-h

33b,c

33g,hP19

P13

P01

P18

P20

P02

P02

P07

P08

P06

P05

P04

P10

P09

P03

P14

P15

P11 P

12

Vario Parking

Ngoolark 34

BASEMENT

P15

P05

BASEMENT

See Inset 1

Inset 1

Building Directory ListJoondalupDestination Building

Grid Ref. Destination Building

Grid Ref. Destination Building

Grid Ref. Destination Building

Grid Ref.

Aroma Café 31 C5

Art Gallery 1 C2

Café 23 23 D5

Café Six 6 D3

Campus Support Office 1 C2

Careers, Volunteering, Mentoring and Leadership Services

34 C4

Centre for Communications and Electronics Research (CCER) 23 D5

Centre for Ecosystem Management 19 F4

Centre for Exercise and Sports Science Research (CESSR) 19 F4

Centre for Innovative Practice 2 C3

Centre for Marine Ecosystems Research (CMER) 19 F4

Centre for Nursing, Midwifery and Health Services Research 21 E5

Chancellery 1 C2

Child Care Centre 12 G4

The Co-Op Shop 31 C5

Crown Hairdressing 9 E3

E-Lab 31 C5

ECU Joondalup Pines E4

ECU Security Research Institute 23 D5

ECU Soccer Club 25 D6

ECU Student Guild 34 C4

ECU Village R G3

ECU Village Administration RA G3

Edith Cowan House 20 E4

Edith Cowan Institute for Education Research 8 D3

Electron Science Research Institute (ESRI) 23 D5

Expo Student Print Services 26 E7

Faculty of Business and Law Faculty Office 2 C3

Faculty of Business and Law Student Information Office 6 C3

Faculty of Education and Arts Faculty Office 8 D3

Faculty of Education and Arts Student Information Office 8a D3

Faculty of Health, Engineering and Science Faculty Office 21 E5

Faculty of Health, Engineering and Science Student Information Office

18 E5

Fogarty Learning Centre 8 D3

Graduate Research School 34 C4

Health and Wellness Institute /Vario Wellness Clinic 21 E5

iSyte Optometrist 6 C3

La Mint Café 1 C2

Lecture Theatres

7.101, 7.102, 7.103, 7.104 7 D3

8.101, 8.211, 8.213, 8.303, 8.305 8 D3

19.141, 19.143 19 F4

32.101 32 C4

Library 31 C5

Maintenance— Buildings and Services 26 E7

Medical Centre 6 C3

Micro Brewery 9 E3

Multifaith Chaplaincy Service 34 C4

Mussallah 17j, k F3

Nala Karla Lounge 34 C4

Nala Karla Reflection Space (NKRS) 34 C4

Ngoolark 34 C4

Perth Graduate School of Business 2 C3

Perth Institute of Business and Technology (PIBT) 31 C5

Pure and Natural Café 22 E6

School of Business 2 C3

School of Computer and Security Science 18 E5

School of Education 8 D3

School of Engineering 23 D5

School of Exercise and Health Sciences 19 F4

School of Law and Justice 2 C3

School of Medical Sciences 21 E5

School of Natural Sciences 19 F4

School of Nursing and Midwifery 21 E5

School of Psychology and Social Sciences 30 D4

Security and Traffic Services 1 C2

The Sellenger Centre 2 C3

Slice of Italy Café 9 E3

Social Justice Research Centre 4 D4

Sport and Fitness Centre 22 E6

Student Central 34 C4

Student Connect 34 C4

Student Counselling Services 18 E5

Student Equity, Diversity, and Disability Service

18 E5

Student Lounges

Student Lounge 8 D3

Student Lounge 31 D5

Student Lounge 34 C4

Student Recruitment 1 C2

Student Services Directorate 34 C4

Systems and Intervention Research Centre for Health (SIRCH)

21 E5

Tavern 9 E3

Twin Cities FM 18 E5

Wandjoo/Welcome Reflection Space (WWRS) 1 B2

Edith Cowan University, 270 Joondalup Drive, Joondalup WA 6027

Visiting Professor Xu Dong Zhang   Title:  ‘Regulation of PD‐L1 expression in cancer cells’  Edith Cowan University, Joondalup Campus August 8th at 10‐11am Room 31.447 

 Summary  DRIVER OF CHANGE 

Head of the Melanoma Research Laboratory at the University of Newcastle and Calvary Mater Newcastle Hospital, Professor Zhang has spent the past 15 years searching for a cure for metastatic melanoma. Navigating the cellular highways of skin cancer is a complex journey and Professor Xu Dong Zhang is a driving force in mapping the pathways of melanoma that have, until recently, remained a mystery. One of the world's most eminent researchers in skin cancer, University of Newcastle's Professor Zhang discovered a molecular pathway that has the potential to save the lives of people diagnosed with melanoma, the most dangerous form of skin cancer. More than 130,000 melanomas are diagnosed worldwide with 1,500 Australians dying from the disease each year. Australia holds the unfortunate title of the highest incidence of melanoma in the world. 

THE ROAD TO A CURE 

In 2013, Professor Zhang was the Chief Investigator for an international collaboration that unearthed a molecular pathway that plays an important role in the development of melanoma and its resistance to treatment. "There are tens of thousands of genes in every cell so discovering the important ones is an art. It takes a lot of work and lot of faith but Xu Dong has a knack for picking the right molecules," said fellow University of Newcastle cancer researcher, Dr Rick Thorne. Cancer is caused by the uncontrolled division of cells, which can invade adjacent tissue or travel through the body in a process called metastasis. In the majority of cases, cancer researchers look for deregulated genes that drive cell division. "Our finding changes not only the way we view melanoma, but could also have significance for other kinds of cancer," Professor Zhang said. Professor Zhang and his team found they could inhibit the growth of melanoma cells, and even shrink established melanomas. "The pathway identified was commonly absent in melanoma cells. By restoring its expression, it actually made the melanoma cells behave more normally and this happened straight away," Professor Zhang said. Professor Zhang said his team is now exploring targeted approaches to blocking the Akt pathway and hope they will have a new melanoma treatment within the next few years.   

DD

Multi_ Deck Car ParkPhase 2

Western Power

Sub Station

C

X

EmergencyHelipad

D

CC

ZZZ

Staff Car Park 6

T

N

Staff Car Park 3

V

A

M J

G

F

L K

Lions Eye Inst

E

R

Under Construction Win

thro

p A

ve

Ho

sp

ita

l A

ve

To Perth

To Stirling Hwy

Hollywood Private Hospital

B

INSTITUTE

UnderConstruction

(New Children’s Hospital)

UWA Car Park

Ga

ird

ner

Dr

EMERGENCY

M

ChildCare

Visitor Car Park 7 8.00am - 4.00pm

Kin

gs

Park

WW YY

Staff Car Park

7A

Verdun St

Kin

gsto

n S

t

Ca

mp

sie

St

Monash Ave

Aberdare Rd

Ha

mp

den

Rd

AdmissionsMain Entrance &

G Street

Under Construction

Ca

lad

en

ia C

res

Visitor Car Park 3A

Visitor Car Park 1

M

Visitor and Staff Multi Deck Car Park(Entry off Winthrop Ave Only)

HH

Ca

lad

en

ia C

res

Q P PathWest

Car Park 7B

S

S

S

S

S

S

S

S

S

Main Entrance

Wa

tlin

g W

alk

S

S

E Street

Main

N

JJ

Your Guide to the

HARRY PERKINS INSTITUTE

OF MEDICAL RESEARCH

M

Taxi

S Set down (Drop Off Bays)

Undercover Access

Main Roads

Pleasant Rest Area

Playground

Bicycle Path

Road Areas

What

is w

here A Research Institutes, SCGH Security Dept,

Physiotherapy, Patient Liaison Service (D3)

AA Lions Eye Institute (C3)

B Respiratory Medicine, WA Institute for Medical Research (B4)

C Dept Rehabilitation and Aged Care (B4)

CC The Niche (B4)

D SCGH Psychiatric Unit (Ward D20) (B3)

DD Cancer Centre (B3), SCGH Oncology, Haematology Clinic, Radiation Oncology (D4)

E Travelsmart Junction, Post Graduate Medical Education, Retail Centre, Outpatients Clinic, State Head Injury Unit, Haematology Clinic, Chapel, Discharge Ward (enter from Rose Garden) (C4)

F Radiation Oncology (D4)

G SCGH Main Ward and Theatre Block (Wards G41 - G75 and Emergency Dept) (D4)

HH Central Energy Plant (D1)

J PathWest Reception & Specimen Collection (E4)

JJ Bereavement Viewing Room (E4)

K PathWest South (E4)

L UWA School of Medicine (E3)

M UWA School of Medicine (E3)

N UWA Offices (E3)

P Lecture Theatres (D2)

PP PathWest Pathology (D2)

Q SCGH Education and Development (D2)

R UWA and SCGH Depts, Occupational Safety and Health, Heart Research Institute, Parking Department (D2)

T NMHS Executive Offices, NMHS Redevelopment (D1)

V SCGH Communications Centre (D3)

WW Engineering Stores, Metal Trades Workshop, Waste Management (D2)

X St Johns Ambulance Depot (A5)

YY Dangerous Goods Store, BOC Office, Radiation Store (D2)

Z Crawford Lodge (F3)

ZZ OHCWA and Medical Library (F4)

1 2 3 4 5

A

B

C

D

E

F

Ab

out Issue #5 July - September 2013

Next Issue: October 2013

QEIIMC GUIDE

The QEIIMC Guide is updated quarterly and it can be found throughout the medical centre. If you have a business, service or an event that you would like to promote in the guide please phone 9346 3964 or email qeiimctrust@health.wa.gov.au

Transp

ort BUS ROUTES AND TRAIN

STATIONS

BUSES STOPPING AT QEIIMC

24 & 25 East Perth to Claremont Train Station

79 Wellington St Bus Station, Esplanade Bus Port to QEIIMC

97 Subiaco Train Station to UWA

98 & 99 Circle Route - travels in a circle outside the city

103 Fremantle to East Perth

TRAINS

Subiaco Train Station - catch 97 bus

Stirling Train Station - catch 98 bus

Shenton Park Train Station - catch 98 bus

Esplanade Train Station - catch 79 bus or walk to St Georges Terrace and catch 24, 25 or 103 bus

For more information on public transport in the area visit www.transperth.wa.gov.au or call the Transperth Hotline on 13 62 13.

find

us

Park

ing The main visitors car park is the Multi Deck

facility accessible from Winthrop Avenue. The adjacent visitor car park 1 is only accessible through the Multi Deck car park.

Client Insert Date

Campaign Size (HxW)

Description

Filename Proof/Alt #

Publication Date/Time

Prod Mgr

Studio Mgr

Studio Op

Acc Dir

Acc Coor

Art Dir

Writer

Notes: Grey fields for internal sign off on hard copy proof.

PDF may appear on screen not at actual size.

QE Medical Centre (QE11) 2013-04-04

QEII000044 Site Map - July Edition 290.0 x 600.001

2013

QE11000044_Map_Issue_5_2-2 3

QEII Map edition 4 2013-07-04 11:35

ACROD Parking

Telephone

Motorcycle ParkingM

Bicycle Parking

Staff Secure Bicycle End of Trip Facility

Taxi

TravelSmart Junction

ATM

Visitors Car Parking

Underground Car Parking

Bus Stop

Shops

Post Office, Cafe, Shops & Chemist

S Set down (Drop Off Bays)

Undercover Access

Main Roads

Pleasant Rest Area

Playground

Bicycle Path

Road Areas

HARRY PERKINS

To Harry Perkins

Staff Car Park 4

We are honoured to have Professor Chris Reid as our guest speaker at next Monday’s (August 8, 2016) Saint John of God Subiaco Hospital Research and Ethics Education Program.  Professor Christopher Reid is a cardiovascular epidemiologist with appointments as Research Professor in both the School of Public Health at Curtin University in Perth and the School of Public Health and Preventive Medicine, Monash University in Melbourne. He is Director of the Monash Centre of Cardiovascular Research and Education in Therapeutics and the NHMRC Centre of Research Excellence in Cardiovascular Outcomes Improvement (2016‐2020). He holds a National Health and Medical Research Council Senior Research Fellowship in addition to being the Chief Investigator on an NHMRC Program Grant (2016‐2020) focusing on cardiovascular disease prevention. His major research interests include clinical outcome registries, randomised controlled trials, and epidemiological cohort studies. He has been Study Director for the 2nd Australian National Blood Pressure (ANBP2) Study and currently a Chief Investigator for the Aspirin in Reducing Events in the Elderly (ASPREE) Study, the Statins in Reducing Events in the elderly Trial and the Australian arms of the HOPE‐3, REACH and CLARIFY Registries. He is a Principal Investigator for the Victorian Cardiac Procedures Registry Project, the Melbourne Interventional Group (MIG) registry, and the ANZSCTS National Cardiac Surgical Registry. He has over 300 peer‐reviewed publications, many of which are in leading journals including the New England Journal of Medicine, Lancet, JACC and the BMJ. He participates as a WHO consultant for prevention of cardiovascular disease in Mongolia, Vietnam and the West Pacific region.  Topic:                                    Clinical Registries – Research data collection to facilitate evidence based practice  Date and Time:                 Monday August 8, 2016 @ 1pm  Venue:                                 St John of God Subiaco Hospital, Conference Centre, Level 3 Auditorium  Who should attend:       Principal Investigators, Co‐Investigators, Investigator Initiated Study personnel, Research Study Managers and associated Research Study – Clinical Trial Personnel  We hope you can join us at this presentation.  Kind regards  Catherine  Catherine May | Manager - Clinical Trials Safety & Compliance St John of God Subiaco Hospital T: 08 93826213 | M: 0415498494 | F: | E: Catherine.May@sjog.org.au 12 Salvado Road Subiaco WA 6008 | PO Box 14, Subiaco WA 6904 http://sjog.org.au/subiaco | http://twitter.com/sjog_healthcare | LinkedIn | http://facebook.com/StJohnOfGodSubiacoHospital  

The University of Western Australia

Campus map

S E A R C H

Go

Arts Lecture Room 5 (ALR5 106:G61) - Ground Floor

Room G61 (Arts Building)

I N D E X

Academic

Administration

Colleges

Food and beverages

Galleries

Gardens

Lecture Theatres

Libraries

Museums

Sport Facilities

Staff Services

Student Services

Theatres

Parking

Virtual Tours

Meeting Room

Examination venues

A C C E S S ▼

F U R T H E R I N F O R M A T I O N

UWA campus map [PDF, 1.2 MB]

Updated 3 Nov 2015

UWA and surrounds [PDF, 601.0 KB]

Updated 3 Nov 2015

Site plan with building names [PDF, 357.3 KB]

Updated 3 Nov 2015

Map of parking areas [PDF, 229.8 KB]

Updated 18 Jan 2016

Edit this area in Google Map Maker

Contact Digital and Creative Services with feedback or

suggestions

Arts Lecture Room 5 (ALR5 106:G61) - Ground Floor Room G61 (Arts Building)Link to this location

Map data ©2016 Google

CMCA Seminar Series in association with ANZMAG

Centre for Microscopy, Characterisation and Analysis

“Why NMR Matters in Metabolomics”

Monday 8 August 2016 Venue: Ground Floor Room G61, Arts Building 3 – 4 pm http://www.web.uwa.edu.au/contact/map?id=2195

David S. Wishart, Professor, Departments of Biological Sciences and Computing Science, University of Alberta Director, The Metabolomics Innovation Centre (TMIC)

David Wishart (PhD Yale, 1991) is a Professor in the Departments of Biological Sciences and Computing Science at the University of Alberta. He is also a senior research officer and the director of the Nano Life Science program at the NRC’s National Institute for Nanotechnology (NINT). He has been with the University of Alberta since 1995. Professor. Wishart has active research programs in structural biology, nanobiology, synthetic biology, prion biology, bioinformatics and metabolomics. Some of his lab's most significant contributions have been in the area of protein chemical shift analysis and the prediction of protein structure.

In principle, NMR is an ideal technique for metabolomics. It is non-destructive, non-biased, highly quantitative, requires no prior separation, permits the identification of novel compounds and needs no chemical derivatization. However, relative to other analytical techniques NMR is slow and relatively insensitive. Furthermore the identification and quantification of compounds in mixtures by NMR is manually intensive and often error-prone. Because of these limitations, NMR is being supplanted by mass spectrometry for many metabolomic applications. In this presentation I will highlight some recent developments in the field of NMR-based metabolomics and show how NMR can be used to match or even exceed the speed, sensitivity and metabolite coverage claimed by various mass spectrometry methods. In particular, I will describe our recent efforts to completely automate NMR-based metabolomics using a software program called Bayesil as well as NMR-based metabolomics kits that we are developing. I will also describe other activities being conducted both in our lab and elsewhere to: 1) enhance the sensitivity of NMR to nanomolar detection; 2) extend the capabilities of NMR to work with tiny samples; 3) provide new vistas for chemical and/or metabolite imaging; 4) measure both metabolites and proteins simultaneously and 5) facilitate novel compound identification and characterization. I will also show how NMR can – and should - play a complementary role to mass spectrometry for metabolomics research, and that NMR still really matters in metabolomics.

Seminars are held in the Anatomy building on the first floor, room 1.81

School of Anatomy, Physiology & Human Biology

The Head of School, Professor Shane Maloney, invites you to attend the

2016 ANATOMY, PHYSIOLOGY & HUMAN BIOLOGY SEMINAR SERIES

Juliana Hamzah

NHMRC-NHF Career Development Fellow Laboratory Head, Targeted Drug Delivery, Imaging and Therapy

Harry Perkins Institute of Medical Research

Novel therapy by selective degradation of abnormal extracellular matrix

Tuesday 9 August 2016 at 1.00pm

Room 1.81, Anatomy, Physiology & Human Biology Building North The University of Western Australia (off Hackett Entrance No. 2)

Dr. Juliana Hamzah is a NHMRC-National Heart Foundation R.D. Wright research fellow with expertise on targeted delivery for imaging and therapy. Previously she was an American Heart Association Postdoctoral Fellow at the Center for Nanomedicine, Sanford-Burnham Medical Research Institute, California (2009-2012). Juliana relocated to Harry Perkins Institute of Medical Research in 2013 and established her laboratory, Targeted Drug Delivery, Imaging and Therapy.

Her research focuses on developing strategies, incorporating bioengineering and nanotechnology platforms, to specifically target pathological lesions including solid tumours and atherosclerotic lesions for local therapeutic intervention and in vivo imaging. Her work was published in journals including Nature, JCI and PNAS.

In this seminar she will present the latest technology and novel drug developed in her laboratory to break tumour stiffness. She will discuss the significance of this approach to detect and treat cancers that are resistant to chemotherapies, including triple negative breast cancer and liver cancer.

PARKING: Coin operated visitor parking is available between Hackett Entrances 1 and 2. City of Subiaco controlled riverside parking is also available.

Enquiries: Debbie Hull: Phone 6488 3313 Fax 6488 1051

Email: deborah.hull@uwa.edu.au www.aphb.uwa.edu.au

Dr Jennifer Rodger is a NHMRC Senior Research Fellow at Experimental and Regenerative Neurosciences, School of Animal Biology, University of Western Australia.

She completed a BScHons in Biochemistry at the University of Bath, UK, followed by a PhD at the University Pierre et Marie Curie, France. Her research team investigates mechanisms of brain plasticity and repair, including preclinical studies of non-invasive brain stimulation in injured and abnormal brain circuits.

Dr Rodger has published over 90 peer-reviewed papers in journals including the Journal of Neuroscience and FASEB Journal and is funded by the NHMRC, ARC and Neurotrauma Research Program (WA).

12:00noon till 1:00pm followed by a light lunch courtesy of Pakair

For more information please contact Associate Professor Julian Heng E: julian.heng@perkins.uwa.edu.au

MCCUSKER AUDITORIUM, HARRY PERKINS INSTITUTE OF MEDICAL RESEARCH, NORTH CAMPUS

Dr Jennifer Rodger NHMRC Senior Research Fellow School of Animal Biology, University of Western Australia

"Brain stimulation in animal models: is it worth the effort?"

THURSDAY 11 AUGUST

Professor Ursula Kees

CLCRF Chair in Children’s Leukaemia; Head, Children’s Leukaemia and Cancer Division Telethon Kids Institute and UWA

Personalised medicine for patients with cancer

Professor Ursula Kees is one of the founding research leaders of the Telethon Institute, establishing the Division

of Leukaemia and Cancer Research in 1990. Her major goals are to understand the underlying genetics of

childhood cancers and to translate the findings into better therapies for patients. International cancer consortia

are sequencing the cancer genome to promote precision medicine in oncology. The aim is to obtain a

comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumour types that

are of clinical and societal importance across the globe. The adoption of sequencing-based genetic tests has led

to extraordinary advances in the development of targeted therapies for cancer patients. Notably, therapy

tailored to the disease of each patient has been pioneered for children with leukaemia. The seminar will provide

an overview of personalised medicine for cancer patients, and insights gained from our chemo-genomic studies

of babies diagnosed with leukaemia.

Friday 12 August 2016

12pm – 1pm Lunch available at 11:45am for those attending the seminar.

RSVP via the calendar invite from Telethon Kids Research Seminars

Telethon Kids Institute Seminar Room

NCARD Seminar:Antigen cross presentation by dendritic cellsProfessor Sebastian AmigorenaDirector of Immunity and Cancer, Institut Curie, Paris

Friday 12 August 201612 noon – 1.00 pm Light lunch to followMcCusker Auditorium, Ground floor, Harry Perkins Institute of Medical Research

Professor Sebastian Amigorena obtained his PhD in Biochemistry and Immunology at University Paris VII in 1990. From then until 1992 he undertook a postdoctoral fellowship on FcR structure and function in B lymphocytes in the Cellular and Clinical Immunology laboratory of Professor Wolf Fridman at the Institut Curie. That was followed by a further 3 year postdoctoral fellowship in the School of Medicine at Yale University, working in the Cell Biology laboratory of Professor Ira Mellman on Cell biology of antigen presentation in B lymphocytes. During his graduate and postgraduate studies he analysed the functions of IgG receptors and described the molecular basis of their inhibitory properties.

Returning to Paris in 1995, Professor Amigorena started an Inserm AVENIR group with Christian Bonnerot. As Director of Immunology (INSERM U932, Cancer Immunity) at the Institut Curie, Professor Amigorena’s main scientific interests are immunology and cell biology. He is an expert in antigen presentation and cross presentation in dendritic cells, and has analysed dendritic cells’ endocytic pathway, and described several unique specialisations of their phagocytic pathway. Professor Amigorena has also made significant contributions to the analysis of cytotoxic T cells dynamics in vivo, during the initiation of immune responses in lymph nodes and during the invasion and rejection of solid tumours.

His more than 200 publications include articles in Nature Immunology, Science, Nature and Cell, and he has been a member of the board of reviewing editors for Science since 2011.

In 2006 Professor Amigorena became one of the youngest members of the French Académie des Sciences.

RSVPs are not necessary, but always welcome for catering purposes. Please contact Tracy Hayward, Administrative Officer, National Centre for Asbestos Diseases Ph: 6151 1078 tracy.hayward@uwa.edu.au

Friday August 12th at 3pm Lecture theatre 7.102 Edith Cowan University, Joondalup campus.   Title: Population Stratification using Personalised Metabolite Trajectories. A Case Study: Metabolomic Changes in Maternal Plasma and Urine During Normal Pregnancy  Speaker: Prof. David Broadhurst, School of Science, ECU.  Abstract:  GWAS has proved to be a powerful tool for uncovering genetic abnormalities linked to disease through untargeted (“unbiased”) analyses of hundreds of thousands of genetic variants; however, these types of  study  explain  only  a  fraction  of  the  total  variance  in  disease  phenotypes.  It  is  clear  that  novel methodologies are needed to capture the full complexity of phenotypic variation. The metabolome is defined as the complete set of low molecular weight chemicals (metabolites) found within a biological system. It can be considered as the final downstream consequence of gene expression, and interaction with the environment. Thus, where genomics will tell you what might happen, metabolomics explains what is actually happening – at a phenotypic level. Many factors modify the metabolome including age, gender, exercise, diet, drugs, viruses, diseases, hormones, stress and environmental exposure. To that end it is reasonable to assume that being cognisant of longitudinal changes in systemic metabolite concentrations may be an effective way to monitor health, and thus stratify patient populations based on abnormal trajectories.  Normal  pregnancy  involves  dramatic  systemwide  physiological  and  biochemical  changes  including alteration  of  the  metabolism  of  carbohydrates,  amino  acids,  lipids,  nutrients,  vitamins  and glucocorticoids  in  order  to  maintain  maternal  and  fetal  homeostasis.  Dysregulation  of  these homeostatic  controls  during  pregnancy  can  lead  to  serious  disorders  such  as  Preeclampsia, Gestational  Diabetes,  Preterm  Birth  and  Fetal  Growth  Restriction.  Longitudinal  monitoring  of circulatory metabolites during pregnancy may be an effective way to monitor maternal/fetal well‐being,  and  provide  early  biomarkers for  personalised  intervention.  In  this  seminar  I  present  a preliminary study to illustrate this hypothesis, and discuss the important role of the biostatistician in this process.    

Want to visualise your omics or epidemiology data? Need an algorithm to speed up your data analysis? Want to develop an app to interact with your patients

or to collect data?

Bring your problem to HealthHack!

HealthHack is a free weekend event bringing medical researchers and health practitioners together with software creators to prototype a new generation

of health products.

To find out more about HealthHack or talk to us about your research problem,

send an email to perth@healthhack.com.au