sex linkage
DESCRIPTION
II. III. XY. IV. or. XX. Sex Linkage. *1909 Thomas Hunt Morgan. *Sex chromosomes *Autosomes. Example: In Drosophila and all mammals sex chromosomes designated as X and Y XX=female XY=male. sex-linkage - transmission and expression of genes on sex chromosomes. - PowerPoint PPT PresentationTRANSCRIPT
Sex Linkage
*Sex chromosomes*Autosomes
Example: In Drosophila and all mammals sex chromosomes designated as X and Y
XX=femaleXY=male
*1909 Thomas Hunt MorganII III IV
XX
XY
or
sex-linkage - transmission and expression of genes on sex chromosomes
X-linkage - transmission and expression of genes on the X chromosome
X-linkage in Drosophila:
white mutation (eyes)
Modifications of Mendelian Ratios
Sex-limited Inheritance:*Sex-limited trait
*holandric genes: genes on the Y chromosome
*autosomal genesExample: milk production in mammals; L=lots, l=little
*Sex-influenced trait
Sex-influenced Inheritance:
Examples:
*cleft palate in humans*horns in sheep *pattern baldness in humans
Summary:
Sex-linked on X or Y sex-chromosome
Sex-limited all or none expression by sex
Sex-influenced genotype + sex determines phenotype
*Phenotype depends on environment and genes
Phenotypic Expression:
*Penetrance
*Expressivity
Gene expression often governed by genotype and environment
If 9/10 of individuals carrying an allele express the trait, the trait is said to be 90% penetrant
*Onset of genetic expression
*Temperature