shaykkh shahbaaz project ppt zeroth review
DESCRIPTION
really goodTRANSCRIPT
1
Project Phase I
04/20/2023
Dept. of Electronics Engg. Pondicherry University
“A CMOS Diaphragm Based Label-Free DNA SoC Detection with Improved Sensitivity & Efficiency”
Presented by: Under The Guidance of
Shabaz Ahmed Sheikh.SSDr T Shanmuganantham
M Tech [Electronics], 2nd Year Asst.Professor
12304013
Dept Of Electronics Engineering,
Pondicherry University,
Puducherry
2
Out Line
04/20/2023Dept. of Electronics Engg. Pondicherry University
oMotivation oObjectiveoExisting ModeloProblems In Existing ModeloProposed ModeloExpected improvement in proposed modeloWork PlanoReferences
3
Motivation
04/20/2023Dept. of Electronics Engg. Pondicherry University
DEOXYRIBONUCLEIC acid (DNA) detection is an important analytical method in molecular biology, and it finds a wide range of applications from genetic disease diagnostics, medicine and drug discovery, to forensic investigation and food testing, etc.
This way we can and will be able to diagnose and detect the fatal diseases like HEPATITIS, CANCER, TB hands on without any special technique required .
This if done on a large scale can bring down the cost of this Lab-On-Chip device drastically and will be boon to the mankind.
4
Objective
04/20/2023Dept. of Electronics Engg. Pondicherry University
To design a CMOS Diaphragm Based Label-Free DNA SoC Detection with Improved Sensitivity & Efficiency
5
Existing Model
04/20/2023Dept. of Electronics Engg. Pondicherry University
04/20/2023Dept. of Electronics Engg. Pondicherry University
6
Existing Model Contd………
7
Problems In Existing Model
04/20/2023Dept. of Electronics Engg. Pondicherry University
Resistance based .(piezoresistive)Sensitivity can further be improved.Interference due to unspecific binding.Communication/data rate to external wireless can be
improved.Power consumption can further be reduced.
8
Proposed model
04/20/2023Dept. of Electronics Engg. Pondicherry University
Capacitance based,i.e diaphragm will be used by iterating different material combinations
Resistance to frequency converter will be replaced by capacitive converter
QPSK system will be used instead of OOK for external communication
9
Expected Improvements In Proposed Model
04/20/2023Dept. of Electronics Engg. Pondicherry University
Better sensitivity and detectionLower power consumptionHigher data rate
10
04/20/2023Dept. of Electronics Engg. Pondicherry University
Task Subtask Duration Expected Result
T1: Definition and plan Problem definition, methodology and work plan
July1-july25 Study of A CMOS Membrane/Diaphragm Based Label-Free DNA SoC Detection
T2: Application Identifying the applications July26-August10 Easy disease diagnosis eg. CANCER,HEPATITIS,TB, Avian Flu
T3: Proposal of A CMOS diaphragm based label-free DNA soc detection with improved sensitivity & efficiency
T3.1:Theoretical analysis of existing model
August11- August 30 The methodology of design new capacitance or membrane based DNA detection
T4: Simulations
T4.1: Choice of simulation tool
August 31- September 10 Description about the tool to simulate the model
T4.2: Simulation conditions
Sept 11- Oct 1 The parameters and the values of input voltage used to simulate the model
T4.3: Simulations of the proposed model.
Oct 02- Oct 15 The expected result for proposed model
T5: Presentations/submissions T5.1: Report 1
Oct 25 - Nov 25 Report submission for the work so far done
T5.2: viva 1 Nov 9- Nov 30 Explanations for the queries regarding the work so far done
Work Plan
11
References
04/20/2023Dept. of Electronics Engg. Pondicherry University
[1] Y.-J. Huang, C.-T. Lin, L.-G. Chen, P.-Y. Hsiao, B.-R.Wu, H.-T. Hsueh, B.-J. Kuo, H.-H. Tsai, H.-H. Liao, Y.-Z. Juang, C.-K. Wang, and S.-S. Lu, “A fully-integrated cantilever-based DNA detection SoC in a CMOS bio MEMS process,” in Proc. IEEE Symp. VLSI Circuits, 2011, pp. 50–51. C.-W. Huang, T.-H. Lin,
[2] N. Gemma, S. O’uchi, H. Funaki, J. Okada, and S. Hongo, “CMOS integrated DNA chip for quantitative DNA analysis,” in Proc. IEEE Int. Solid-State Circuits Conf., Dig. Tech. Papers, 2006, pp. 560–561.
[3] S.-J. Kim and E. Yoon, “Label-free CMOS biosensor with on-chip noise reduction scheme for real-time quantitative monitoring of biomolecules,” IEEE Trans. Biomed. Circuits Syst., vol. 6, no. 3, pp. 189–196, Jun. 2012.
[4] N. Lajnef, S. Chakrabartty, N. Elvin, and A. Elvin, “Piezo-powered floating gate injector for self-powered fatigue monitoring in biomechanical implants,” in Proc. IEEE Int. Symp. Circuits and Systems, 2007, pp. 89–92.
[5] N. Gemma, S. O’uchi, H. Funaki, J. Okada, and S. Hongo, “CMOS integrated DNA chip for quantitative DNA analysis,” in Proc. IEEE Int. Solid-State Circuits Conf., Dig. Tech. Papers, 2006, pp. 560–561.
12
04/20/2023Dept. of Electronics Engg. Pondicherry University
QUERIES
IF ANY ?
13
04/20/2023Dept. of Electronics Engg. Pondicherry University
Thank You