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TRANSCRIPT
Sheffield Biomedical
Research Centre
Public Launch
This event aims to introduce the NIHR Sheffield Biomedical
Research Centre’s Translational Neuroscience research.
We would like to take the opportunity to thank patients and
the public who give their time to get involved with research.
We hope to present a chance to find out more about what
we do, meet like-minded others, and give more
opportunities for getting involved.
Programme:
12 pm Introductory talk Translational Neuroscience for Chronic Neurological Disorders by Director, Professor Dame Pamela Shaw
12:20 Join us for a buffet lunch and networking opportunity in the lobby
12:45 Advanced Medical Imaging for Neurology
by Professor Iain Wilkinson
1 pm Do Virtual Patients see Electric Doctors?
by Professor Marco Viceconti
1:15 Group activities
We will invite attendees to join groups to be guided through 4 activities
2:15 Teas, Coffees, and festive refreshments
2:30 Have your say in an Ask the Audience live polling research involvement exercise with Professor Chris McDermott
2:45 3 pm
Meet Patient and Public Involvement organisers, reclaim travel expenses and exchange contact details if you wish
Close
Advanced Medical Imaging for Neurology
New medical scanning techniques will
support how we can diagnose patients earlier
and get conclusive results in trials for new
treatments. Find out what we are developing
and what the future of medical imaging may
look like in 5 years’ time.
Professor Iain Wilkinson
Translational Neuroscience for Chronic
Neurological Disorders
My talk introduces the ways in which we are
addressing our main research areas of Motor
Neurone Disease, Parkinson’s Disease,
Dementia, Multiple Sclerosis, and Stroke
Professor Dame Pamela Shaw
Do Virtual Patients see Electric Doctors?
Computer models and simulations can to help
diagnose, manage and predict better
treatments for neurological diseases. In Silico
(computerized) medicine has the goal of
speeding up the process of finding more
effective therapies. By gathering
comprehensive biological data we aim to build
virtual patients to improve clinical trial design.
Professor Marco Viceconti
Group Activities
If you turn your name badge over you will find a
picture. Our friendly ushers and trainees will help
to take you around these 4 activities in groups
during the next hour.
What is a genome? What is genomic
sequencing? And how will these things help our
research into neurological disorders? Members
of our Genomic Medicine and Bioinformatics,
and Motor Neurone
Disease research teams will use
the Genomics Education
Programme game to help to
explain the era of genomic
medicine we are living in and ask
you what you think about it.
Drs Dennis Wang, Stephanie
Shepheard and Mark Dunning
Play the Genomics Game
Understanding people's experiences through
creativity: Introducing The KAWA (river of life) Model
In this model the river is your life
journey, the boulders are life
circumstances. The art work example I
created to the left represents a Multiple
Sclerosis (MS) diagnosis as a large
boulder and goes on to depict my
experience with HSCT (hematopoietic
stem cell transplantation) therapy. The
Model can be applied to any journey.
I’m using it to collect people’s
experience with HSCT for relapsing
remitting Multiple Sclerosis in my own
research.
Colette Beecher
Wearable Sensors to measure
movement disorders
‘Tap vs Cap’ can you tell the difference between tap
water and bottled in a randomized doubled-blind
mock trial?
Would you like to know more about
clinical trials? This session aims to
help understanding about
randomization and double-blind trials
(perhaps cross-over design too, if
there’s time). Learn what these
words mean through a simple water
taste test, conducted by members of
the Sheffield Teaching Hospitals
Clinical Research and Innovation
Office team.
Dan Lawrence, Jodie Keyworth, Alisha Patel and Jennie Smith
Many neurological disorders carry a hallmark of
changes in gait and other movements.
Researchers from The Insigneo Institute for in
silico Medicine will demonstrate how movement
can be tracked objectively to help monitor
changes over time and in response to
treatment. Would you wear these around your
home to be monitored for movement changes?
Drs Claudia Mazza and Lorenza Angelini
Contact Details
If you would like to find out more about patient and
public involvement in research please contact one
of the co-ordinators listed here:
NIHR Sheffield Biomedical Research Centre Laura Evans [email protected] 0114 222 2268
Sheffield Motor Neurone Disorders Research Advisory Group Annette Taylor [email protected] 0114 222 2289
NIHR Sheffield Clinical Research Facility Liz Ralph [email protected] 0114 271 5114
South Yorkshire Dementia Research Advisory Group Jane Mckeown [email protected] 0114 222 2071
Parkinson’s UK Anna-Louise Smith [email protected]
For further information: Sheffield Teaching Hospitals NHS Foundation Trust Clinical Research and Innovation Office www.sheffieldclinicalresearch.org 0114 226 5938 JACKIE PALMER Clinical Research Administrator
[email protected] [email protected]
Yorkshire and Humber Genomic Medicine Centre PPI Panel Debbie Bearne [email protected] .
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sign out desk
Thank You
The image on the cover is called ‘Dancing
Flowers Astrocytes’ by 2nd Year PhD student,
Noemi Gatto, supervised by Dr Laura Ferraiuolo
at the Sheffield Institute for Translational
Neuroscience. The image was taken with
equipment in our drug screening facility and
shows a type of brain cell called astrocytes.
These cells have been reprogrammed from the
skin cells of patients so we can study them in
close detail and see how potential new
treatments may affect their biology.