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Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering Cancer Center, New York NY Hassan Mostafavi, Alexander Sloutsky, Andrew Jeung Varian Medical Systems Inc., Palo Alto CA

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Image Enhancement using Short Arc DTS  Example scenario: Gantry rotation during treatment e.g. RapidArc  Use MV projections over last θ degrees to reconstruct a DTS image  Targets that would otherwise be obscured by scatter noise and overlaying structures will be enhanced sufficiently for successful automatic tracking

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Page 1: Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering

Short Arc Digital Tomosynthesis as an Image Enhancement Step

for Detection and Localization of Implanted Markers

Margie Hunt, Pengpeng Zhang

Memorial Sloan-Kettering Cancer Center, New York NY

Hassan Mostafavi, Alexander Sloutsky, Andrew Jeung

Varian Medical Systems Inc., Palo Alto CA

Page 2: Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering

• Automatic detection of implanted radio-opaque markers can be challenging due to noise, scatter, and obfuscating structures

• Image enhancement by Short Arc Digital Tomosynthesis (DTS) – tomosynthesis reconstruction over a 3 – 5° arc – may enhance images to aid detection

• Enhancement can be quantified by matching to an image template and calculating the peak-to-sidelobe ratio (PSR) of the resulting match surface

Study Objectives

Page 3: Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering

Image Enhancement using Short Arc DTS

Example scenario: Gantry rotation during treatment e.g. RapidArc

Use MV projections over last θ degrees to reconstruct a DTS image

Targets that would otherwise be obscured by scatter noise and overlaying structures will be enhanced sufficiently for successful automatic tracking

Page 4: Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering

Results

Comparison of original MV images (left) to DTS-enhanced images (right). DTS-enhanced markers are easier to identify, and band artifacts due to linac are eliminated.

a

b

PSR = 5.812

c

PSR = 8.251

Template of markers generated from plan CT (a) matches with the DTS-enhanced image (c) with a higher PSR score than with the original MV projection (b).

Page 5: Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering

Gantry AnglePSR:

Template to original image

PSR:Template to

DTS-enhanced

image

21.3° 5.812 8.251

49.0° 3.007 5.666

81.0° 3.031 3.734

DTS enhancement results in a consistently higher peak-to-sidelobe ratio (PSR)

Page 6: Short Arc Digital Tomosynthesis as an Image Enhancement Step for Detection and Localization of Implanted Markers Margie Hunt, Pengpeng Zhang Memorial Sloan-Kettering

Conclusions

• Short Arc DTS can enhance image sequences acquired during gantry rotation

• It shows promise in making detection and localization of markers more robust and accurate

• Template matching and use of peak-to-sidelobe ratio can quantify the improvement in detectability