silk fibroin wound dressings
DESCRIPTION
Silk Fibroin Wound Dressings. Used for Regenerative Healing Therapies. Sierra Obi April 1, 2013. Cutaneous Wounds. Include severe burns, animal bites, skin tears There are numerous wound dressing biomaterials on the market today - PowerPoint PPT PresentationTRANSCRIPT
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SILK FIBROIN WOUND DRESSINGS
Used for Regenerative Healing TherapiesSierra ObiApril 1, 2013
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Cutaneous Wounds
Include severe burns, animal bites, skin tears There are numerous wound dressing biomaterials
on the market today Tested against an air permeable and a commercial
wound dressing product
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Silk Fibroin
Promising biomaterial Versatile for various biomedical healing
applications Mechanical robustness Controllable degradability Safe in acute dermal toxicity
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How They Work
Silk Fibroin derivative is tested on a full thickness skin wound model or an in vitro human skin model
controlled release of signaling molecules Addition of in vivo epidermal growth factor and
silver sulfadiazine
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Wound Healing Model
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Relationship of Wound Size
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References
http://onlinelibrary.wiley.com/doi/10.1002/adhm.201200444/full
http://onlinelibrary.wiley.com/doi/10.1002/adhm.201200192/full
http://www.sciencedirect.com/science/article/pii/S1742706108004054
http://www.nejm.org/doi/full/10.1056/NEJMra0707253