simulating attentional blink with a neocortical attractor model
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Open AccePoster presentationSimulating attentional blink with a neocortical attractor modelDavid Silverstein* and Anders LansnerAddress: School of Computer Science and Communication, Royal Institute of Technology, Stockholm, Sweden
Email: David Silverstein* - [email protected]
* Corresponding author
This study simulates attentional blink or "blink of themind," a phenomenon where a human subject missesperception of a later expected visual pattern as twoexpected visual patterns are presented less than 500 milli-seconds apart. With an abstract computational model ofthe neocortex, a cortical patch is stimulated with asequence of patterns at varying time points. Patterns thatbecome active attractors are considered recognized.
A neocortical patch is represented as a square matrix ofhypercolumns, each containing a set of minicolumns withsynaptic connections both within and across both mini-columns and hypercolumns [1]. Each minicolumn con-sists of locally connected layer 2/3 pyramidal cells withinteracting basket and bipolar/double bouquet interneu-rons. All neurons are implemented using the Hodgkin-Huxley multi-compartmental cell formalism and includecalcium dynamics, synaptic depression and saturatingAMPA, NMDA and GABA synapses. Active patterns areencoded with global connectivity of minicolumns acrosshypercolumns and they inhibit each other.
Stored patterns were stimulated at sliding differential timepoints to create neural attractor interference measurablewith synthetic electrode traces. The effect correspondedwith human visual attentional blink studies. Additionally,studies on the inhibitory effect of the drug class benzodi-azopine on attentional blink in human subjects werecompared with neocortical simulations where an inhibi-tory GABA receptor conductance was increased. Simula-tions showed increases in the attentional blink duration,
agreeing with observations in human studies. Figures 1and 2.
from Eighteenth Annual Computational Neuroscience Meeting: CNS*2009Berlin, Germany. 18–23 July 2009
Published: 13 July 2009
BMC Neuroscience 2009, 10(Suppl 1):P309 doi:10.1186/1471-2202-10-S1-P309
<supplement> <title> <p>Eighteenth Annual Computational Neuroscience Meeting: CNS*2009</p> </title> <editor>Don H Johnson</editor> <note>Meeting abstracts – A single PDF containing all abstracts in this Supplement is available <a href="http://www.biomedcentral.com/content/files/pdf/1471-2202-10-S1-full.pdf">here</a>.</note> <url>http://www.biomedcentral.com/content/pdf/1471-2202-10-S1-info.pdf</url> </supplement>
This abstract is available from: http://www.biomedcentral.com/1471-2202/10/S1/P309
© 2009 Silverstein and Lansner; licensee BioMed Central Ltd.
AB simulation with 5 of 9 stimulated minircolumns (18 trials)Figure 1AB simulation with 5 of 9 stimulated minircolumns (18 trials).
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References1. Lundqvist M, Rehn M, Djurfeldt M, Lansner A: Attractor dynamics
in a modular network model of neocortex. Network: Computa-tion in Neural Systems 2006, 17:253-276.
2. Boucart M, de Visme P, Wagemans J: Effect of benzodiazepine ontemporal integration in object perception. Psychopharmacology(Berl) 2000, 152:249-255.
Human AB benzodiazepine study [2]Figure 2Human AB benzodiazepine study [2].
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