single flap approach with and without guided tissue

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    Single flap approach with and without

    Guided Tissue Regeneration

    and a Hydroxyapatite biomaterial in themanagement of intraosseous periodontal defects

    Leonardo Trombelli, Anna Simonelli, Mattia Pramstraller,Ulf M.E. Wikesjo, and Roberto Farina

    Kim YunJeong

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    Single flap approach ?

    Minimally invasive surgical technique: lessen surgical trauma with adequate access

    : limited or no use of release incisions, limited flap reflection

    SFA (single flap approach): unilateral elevation of a limited mucoperiosteal flap to allow

    surgical access depending on the main, buccal or oral,extension of the intraosseous defect leaving adjoininggingival tissues intact

    Trombelli L 2007

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    Single flap approach (SFA)

    facilitate flap repositioning and suturing

    : can easily be stabilized to the undetached papilla, optimizing wound closure for primary intention healing

    accelerated reestablishment of the local vascular supply

    preservation of the pre-existing gingival esthetics

    SFA combined with a hydroxyapatite (HA) and GTR allowedsubstantial clinical attachment gain,

    limited gingival recession (REC),

    generally uneventful healing in deep intraosseous defects.

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    Background

    GTR was more effective than OFD(open flapdebridement) in improving attachment levels

    Needleman I, Tucker R, Giedrys-Leeper E, Worthington H..A systematic review of guided tissue regeneration for periodontal

    infrabony defectsJ Periodontal Res. 2002

    Challenging intraosseous defects, surgicallyaccessed with a buccal SFA and treated with acombined graft/GTR technique, may heal with a

    substantial CAL gain.Leonardo Trombelli .. Single-Flap Approach With Buccal Accessin Periodontal Reconstructive Procedures J Periodontol 2009

    application of a wound stabilizing element; GTR device ora biomaterial, allowed wound healing progressing onto a

    connective tissue attachment , not epithelial attachment

    http://www.ncbi.nlm.nih.gov/pubmed?term=%22Needleman%20I%22[Author]
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    single-center randomized-controlled trial

    Patients1) diagnosis of chronic or aggressive periodontitis

    2) no systemic diseases that contraindicated periodontal surgery3) no medications affecting periodontal status

    4) no pregnancy or lactation

    5) presence of 1 deep ( PD5 mm, radiographic depth 4 mm)interproximal intraosseous periodontal defect limited to no

    extension on the lingual-palatal side as assessed by

    preoperative bone sounding

    6) full mouth plaque score and bleeding score

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    Each intraosseous defect was randomly assignedto receive SFA or SFA + HA/GTR

    The patients and the clinical examiner weremasked with respect to treatment allocation

    SFA after full mouth SRP and oral hygiene

    instruction.

    Materials and Methods

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    Probing

    buccal envelope flap

    without vertical

    releasing incisions

    Sulcular incisions are performed followingthe gingival margin of the teeth

    interdental incision is performed >1 mm coronalto the underlying bone crest

    Materials and Methods

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    Flap elevation Debridement using hand and ultrasonicinstruments

    HA-based biomaterial (BIOSTITE) and

    resorbable collagen membrane (PAROGUIDE)

    Materials and Methods

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    horizontal internalmattress suture

    second internal mattress suture

    Materials and Methods

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    2wk post-op

    Inhibit 4wks mechanical oral hygiene procedure

    0.12% chlorhexidine mouthrinse (10 ml twice a day for 6 weeks)

    antimicrobial AmF/SnF2 mouthrinse and toothpaste

    Monthly R/C with supragingival plaque control

    6mo post-op

    Materials and Methods

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    Recordings One calibrated masked examiner

    manual pressure-sensitive probe with 1-mm increments

    approximately 0.3-N force

    PD (gingival margin~bottom of the pocket)

    CAL (CEJ~bottom of the pocket)

    REC (CEJ~gingival margin)

    bleeding score (+/-) ->measured at 6 aspects per tooth

    presurgery/ post op 6mo

    Materials and Methods

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    Recordings configuration of the intraosseous defect

    depth of the intrabony component

    : deepest point of the defect ~most coronal point of thealveolar crest at the adjacent tooth

    statistical software program Student t test , x2 test

    early wound-healing index (EHI, Wachtel,2003)

    1) complete flap closure, no fibrin line in the interproximal area

    2) complete flap closure, fine fibrin line in the interproximal area3) complete flap closure, fibrin clot in the interproximal area4) incomplete flap closure, partial necrosis of the interproximal tissue5) incomplete flap closure, complete necrosis of the interproximal tissue.

    Materials and Methods

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    Results

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    Results

    5 defects inSFA+HA/GTRgroup showedlimited (

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    Results

    12 SFA versus 7 SFA + HA/GTR defects

    showed a post-surgery PD

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    Discussion

    HA-based biomaterial: SFA + HA/GTR group displayed considerable

    CAL gain (4.7 mm) and PD reduction (5.3 mm)

    -> consistent with previous studies of conventional flap + HA/GTR

    Five sites in the SFA + HA/GTR group exhibitedsuture-line dehiscences that apparently resolved

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    SFA supported considerable clinical improvements asa stand-alone protocol

    : CAL gain averaged 4.4 mm, 11 sites >3 mm gain

    at 6m post op

    The effect of SFA largely exceeded those reportedfor conventional access flaps in the treatment ofintraosseous periodontal defects.

    : limited surgical trauma and optimal conditions

    for wound closure/wound stability

    Discussion

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    Variations in supracrestal and osseousdefect characteristics

    presurgery supracrestal tissue thickness for the SFA(2.4mm) compared to the SFA +HA/GTR group (1.1 mm)

    SFA group exhibited greater prevalence sites with

    3-wall component

    The depth of the intrabony component

    :SFA (6.1mm) vs. SFA +HA/GTR group (8 mm)

    Discussion

    Treating with barrier membrane, defect

    configuration does not seem to significantlyaffect the amount of CAL gain (Trombelli, 1997)

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    REC increased 0.8 mm in the SFA group compared

    to 0.4 mm in the SFA + HA/GTR group

    REC of the interproximal gingival margin occurreddespite the preservation of supracrestal tissues

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    Conclusion

    SFA with and without HA/GTR seems to bea valuable minimally invasive approach inthe treatment of deep intraosseousperiodontal defects.

    Under the present experimental conditions,the additional HA/GTR protocol offers no

    significant adjunctive effect.

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    Epilogue

    Strong point First trial to compare the effects of SFA and

    SFA+HA/GTR protocol

    Weak point The comparison was not performed in same conditions

    In two groups of 12 patients, baseline defectcharacteristics and age, smoking status .

    were different in many aspects