smartphone-based biomedical human-computer interface

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Smartphone-based Biomedical Human-Computer Interface Spring 2011 Daniel Shapiro; PhD Candidate OCE Student Oral Presentation Competition

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OCE Student Oral Presentation Competition. Smartphone-based Biomedical Human-Computer Interface. Daniel Shapiro; PhD Candidate. Spring 2011. DS: CARG 2011. Biomedicine Problem. Treatments for cognitive impairment:. Drugs: side effects, Cost/Rx $37.44 [6], 2.8M people in Ontario’s - PowerPoint PPT Presentation

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Page 1: Smartphone-based Biomedical  Human-Computer Interface

Smartphone-based Biomedical Human-Computer Interface

Spring 2011Daniel Shapiro; PhD Candidate

OCE Student Oral Presentation Competition

Page 2: Smartphone-based Biomedical  Human-Computer Interface

Biomedicine Problem

carg.site.uottawa.ca

DS: CARG 2011

Treatments for cognitive impairment:Drugs: side effects, Cost/Rx $37.44 [6],

2.8M people in Ontario’spublic drug system [5].

Surgery: only for extreme cases

Cognitive Behavioral Therapy: $40-180/hr [4]

Computer Assisted Cognitive Behavioral Therapy: Works!

Page 3: Smartphone-based Biomedical  Human-Computer Interface

In Search of a Solutions

carg.site.uottawa.ca

DS: CARG 2011

BrainPort, Tang et. al., lots of others…

Novel stimulus is the key: Works better than software-only approach. We opted to develop our own platform with smartphone integration.

Existing solutions focus on:•Aiding the blind, Sensory substitution, Lost balance

Electrode Array facing tongue = Novel Stimulus

Page 4: Smartphone-based Biomedical  Human-Computer Interface

NEAR Overview

carg.site.uottawa.ca

DS: CARG 2011

Inte

rnet

Industry Partner: NorDocs Technology Inc.

collaborative play, real-time image acquisition

Page 5: Smartphone-based Biomedical  Human-Computer Interface

4th prototype (32x32 array)

IntegratedDriver

Board and Electrode

Array

Sept 2011

What’s Happening?

carg.site.uottawa.ca

DS: CARG 2011

1st prototype (5x5 array)[2]

Sept 2010

3rd prototype (8x8 array)

Driver Board

April 2011

2nd prototype (8x8 array)

Driver Board

Jan 2011

Page 6: Smartphone-based Biomedical  Human-Computer Interface

carg.site.uottawa.ca

DS: CARG 2011

Value Proposition1. We estimate the accessible market opportunity in the

cognitive impairment market in Canada to be $1.75 bn/yr.

2. Estimated manufacturing cost of $100 per device

3. Existing solutions are not as flexible as an integrated platform

4. Cash raised = $350K + OCE matching • Currently TPS Lite, working on Collaborate application

and MITACS-accelerate

5. Projected revenue1. $1 million 20122. $3 million 20133. $10 million 2014

Page 7: Smartphone-based Biomedical  Human-Computer Interface

carg.site.uottawa.ca

DS: CARG 2011

Market Readiness 1.Provisional patents are in the works

2.R&D moving quickly towards 2011 human trials

3.FDA - Sec. 882.1320 Cutaneous electrode.Class II (performance standards). [7]510(k) application in 2012Health Canada application in 2011 [8]

4.Ethics application for trial in Ottawa on healthy subjects – Approval for Summer 2011fMRI and inpatient trials Jan 2012

Page 8: Smartphone-based Biomedical  Human-Computer Interface

carg.site.uottawa.ca

DS: CARG 2011

References1. M. Ptito, et al., “Cross-modal plasticity revealed by electrotactile stimulation

of the tongue in the congenitally blind”, Brain, vol. 128, no. 3, pp. 606-614, 2005

2. A. Borisenko, L. Monczak, I. S. Samra, O. Draghici, D. Shapiro, V. Groza, “A Low Cost Bidirectional Human-Computer Interface,” Medical Measurements and Applications (MeMeA), Apr. 2010.

3. H. Tang, D.J. Beebe, "An oral tactile interface for blind navigation," Neural Systems and Rehabilitation Engineering, IEEE Transactions on , vol.14, no.1, pp.116-123, March 2006.

4. http://www.camh.net/care_treatment/resources_clients_families_friends/challenges_and_choices/challenges_choices_abouttherapy.html

5. http://news.ontario.ca/mohltc/en/2010/04/expanding-access-to-affordable-drugs.html

6. http://www.theannals.com/cgi/content/abstract/36/9/13757. http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?

fr=882.13208. http://www.hc-sc.gc.ca/dhp-mps/md-im/applic-demande/guide-ld/

applabel_demmarque_priv-eng.php