smoking and cvd
TRANSCRIPT
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SMOKING & CARDIOVASCULAR DISEASES
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Definition• Never Smokers – Adults who have never smoked a cigarette
or who smoked fewer than 100 cigarettes in their entire lifetime.• Former Smokers – Adults who have smoked at least 100
cigarettes in their lifetime, but say they currently do not smoke.• Nonsmokers – Adults who currently do not smoke cigarettes,
including both former smokers and never smokers.• Current Smokers – Adults who have smoked 100 cigarettes
in their lifetime and currently smoke cigarettes every day (daily) or some days (nondaily).
http://dhds.cdc.gov/guides/healthtopics/indicator
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FACTORS?
• Cigarette smoke contains over 4,000 known components, of which only a few components have been examined in isolation
Carbon monoxide (CO) Polycyclic aromatic hydrocarbons found in the tar
fraction Nicotine Free radical-mediated oxidative stress(Currently
most accepted hypothesis)
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Effects• Cigarette smoking predisposes the individual to
several different clinical atherosclerotic syndromes, including stable angina, acute coronary syndromes, sudden death, and stroke. Aortic and peripheral atherosclerosis are also increased.
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Hung MJ, Hu P, Hung MY. Coronary Artery Spasm: Review and Update. Int J Med Sci 2014; 11(11):1161-1171
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• Passive smoking (environmental tobacco exposure) with a smoke exposure about one-hundredth that of active CS is associated with approximately a 30% increase in risk of CAD, compared with an 80% increase in active smokers