sop: brain mri - rigshospitalet · sop: brain mri author(s) date changes approved by cornelia...

SOP: Brain MRI

Author(s) Date Changes Approved by

Cornelia Hagmann Manon Benders Anne Mette Plomgaard

23.09.2012

1.0 Inital version

Gorm Greisen

CONTENT

1.0 Timing of Brain MRI .......................................................................................1

2.0 Informed consent.............................................................................................1

3.0 Which sequences to take ...............................................................................1

4.0 The procedure .................................................................................................2

5.0 Saving and transferring data to CTU ............................................................3

6.0 Appendix A: scanning detales.........................................................................5

1.0 Timing of Brain MRI Brain MRI should take place between 40 -44 weeks of corrected gestational age.

2.0 Informed consent According to the SafeBoosC protocol separate informed consent must be obtained before conducting the brain MRI. Unless it is localy standard care to have an MRI at term equivalent age.

3.0 Which sequences to take The following sequences should be conducted (if software is available at the study site)

1 sagittal T1 SE

2 coronal T2W 1.2mm

3 coronal T1W 3D

4 DWI with ADC-MAP, either coronal or axial

5 DTI 45 directions axial (angulation left-right zero)

See scanning details in the attachment/appendix.

Some general remarks: 1. be sure the whole brain in scanned including the CSF until outside the skull 2. preferable on 3T, second choice 1.5T 3. for T2/T1 we prefer coronal slices, second choice is axonal/transverse slices 4. slice thickness <2mm, for T1 And T2, scan without a gap (gap zero) 5. Scans we prefer: T1 sagittal, t2W, T1W, DWI, DTI

Country AT

...1.5T, [email protected]

BE ....

CH GE, 3T

DE Siemens 1.5

DK Siemens 3T Magnetom Trio, [email protected]

ES GE1.5 and 3T, Fernando

FR Philips 1.5T, [email protected]

IE Siemens 1.5T

IT Philips, 3T, [email protected]

NL Philips 3T

SE ....

UK GE 1.5T

4.0 The Procedure These are suggested guidelines of how to perform a Brain MRI; however, local instructions may be used. There are two ways on performing the brain MRI: either the infant is scanned during natural sleep or under sedation. For sedation oral Cholralhydrate (50-60 mg/kg) may be used. Before starting:

Make sure that the baby’s body suits and clothes are metal free.

If any surgical metal (PDA clip, VP shunt etc) has been used, one needs to check with the surgeons / radiologists whether it is MR compatible metal.

4.1 Natural sleep: When scanning is done during natural sleep it is essential to plan well in advance:

30-60 minutes before the scanning the mother should feed the child

Change the nappy if necessary

Pulsoximetry is applied on the foot - check the signal.

Place MRI compatible electrodes for monitoring heart rate

Ear plugs and ear muffs are applied (a hat may be applied to keep the ear protection in place)

Wrap a blanket tightly around the baby so that the shoulders and arms are within the blanket.

Check the signal of the heart rate.

If you hav a belly-belt for respiratory rate, we recommend to use this as well

mailto:[email protected]



If using a vacuum mattress

Wait until the baby falls asleep.

Place the baby on the vacuum mattress on the scanner – please make sure that the baby’s head is in the midline before applying the vacuum.

If using an MRI compatible incubator (with / without a vacuum mattress)

Put the child in the MR-incubator

Wait until the child is a sleep

If using a vacuum mattress: please make sure that the baby’s head is in the midline before applying the vacuum

The Scanning can start. If the baby wakes up consider Glucose drops or feeding again. After the scanning is done, the parent(s) can take the baby home. 4.2 Sedation (with oral Cloralhydrate):

Sedation should be given 45 minutes before scanning starts – oral Cloralhydrate (50- 60 mg/kg).

Pulsoximetry is applied on the foot - check the signal.

Place electrodes for monitoring heart rate- check the signal.

(The baby can be fed as long as it still awake.)

The ear protection and the wrapping of the baby is as in the paragraph “natural sleep”.

After the scanning it is advised to keep the baby for 12-24 hours on the monitor when sedation has been used.

5.0 Saving and transferring data to CTU After the first MRI Manon Benders and Cornelia Hagmann must be alerted in order to check the quality of the images.

The MRI data must be saved in the local archive with patient id

Within one month after the MRI is condusted, a copy of the MRI file either anonymised or called by study-id must be send with FTP (File Transfer Protocol) to the CTU (Copenhagen Trial Unit)

For information regarding the data transferring please go to the SafeBoosC homepage and find the SOP: Data transfer to Copenhagen Trial Unit. Link to the SafeBoosC homepage: www.safeboosc.eu

http://www.safeboosc.eu/

6.0 Appendix A: scanning details

3T Philips Sagittal T1W SE (Philips 3T)

Coronal T2 1.2mm (Philips T3)

Coronal T1W 3D (Philips T3)

DWI: Diffusion weighted imaging with ADC-MAP (Philips T3)

DTI: Diffusion Tensor imaging with 45 directions (Philips T3) Multi-transmit = "no"; Nucleus = "H1"; Coil selection = "SENSE-Flex-S"; element selection = "12"; connection = "d"; Dual coil = "no"; CLEAR "yes"; body tuned = "no"; FOV RL (mm) = 160; AP (mm) = 160; FH (mm) = 90; Voxel size RL (mm) = 2; AP (mm) = 2; Slice thickness (mm) = 2; Recon voxel size (mm) =2; Small FOV imaging = "no"; Fold-over suppression = "no"; Reconstruction matrix = 80; SENSE = "yes"; P reduction (AP) = 1.39999998; P os factor = 1; k-t BLAST = "no"; Stacks = 1; type = "parallel"; slices = 45; slice gap = "user defined"; gap (mm) = 0; slice orientation = "transverse"; fold-over direction = "AP"; fat shift direction = "P"; Stack Offc. AP (P=+mm) = -35.4536819; RL (L=+mm) = 3.62022781; FH (H=+mm) = 8.57342815; Ang. AP (deg) = 2.41241336; RL (deg) = 18.1080379; FH (deg) = -5.14448023; Minimum number of packages = 1; Slice scan order = "default"; Large table movement ="no"; PlanAlign = "no"; REST slabs = 0; Shim Size AP (mm) = 87.5996399; RL (mm) = 58.2509651; FH (mm) = 54.9007835; Offc. AP (P=+mm) = -35.4573975; RL (L=+mm) = 4.14247704; FH (H=+mm) = 13.7650223; Ang. AP (deg) = 4.31364822; RL (deg) = 0; FH (deg) = -4.89545584; Catheter tracking = "no"; Interactive positioning = "no"; Allow table movement = "no"; Patient position = "head first"; orientation = "R decub"; Scan type = "Imaging"; Scan mode = "MS"; technique = "SE"; Modified SE = "no"; Acquisition mode = "cartesian"; Fast Imaging mode = "EPI"; shot mode = "single-shot"; Echoes = 1; partial echo = "no"; TE = "user defined"; (ms) = 80; Flip angle (deg) = 90;

TR = "user defined"; (ms) = 6500; Halfscan = "no"; Water-fat shift = "user defined"; (pixels) = 20; Shim = "PB-volume"; ShimAlign = "no"; mDIXON = "no"; Fat suppression = "SPIR"; strength = "strong"; frequency offset = "user defined"; offset (Hz) = 200; Water suppression = "no"; Grad. rev. offres. supp. ="no"; BB pulse = "no"; MTC = "no"; Research prepulse = "no"; Diffusion mode = "DTI"; sequence = "SE"; gradient duration = "maximum"; gradient overplus = "no"; directional resolution ="user defined"; nr of directions = 45; user defined dirs = 1, (2) 0, 0.456999987, 0.889999986, 0, -0.264999986, 0.485000014, 0.833999991, 0.936999977, -0.284000009, 0.202000007, 0.063000001, -0.805999994, 0.588, -0.67900002, -0.0939999968, 0.727999985, 0.686999977, 0.279000014, 0.671000004, -0.232999995, 0.949999988, 0.209000006, 0.922999978, 0.179000005, 0.342000008, -0.111000001, -0.980000019, -0.164000005, -0.131999999, -0.853999972, -0.503000021, 0.367000014, -0.768999994, -0.523000002, -0.291000009, -0.704999983, 0.647000015, -0.675999999, 0.713999987, 0.185000002, -0.598999977, 0.0780000016, -0.796999991, -0.73299998, -0.67900002, 0.0390000008, 0.800000012, -0.216000006, -0.559000015, 0.558000028, -0.340999991, -0.755999982, -0.435000002, -0.598999977, -0.671999991, -0.785000026, 0.596000016, -0.170000002, 0.495999992, 0.791000009, 0.356999993, -0.660000026, 0.433999985, -0.614000022, 0.842000008, -0.144999996, 0.519999981, 0.143999994, 0.430000007, 0.890999973, -0.301999986, 0.282000005, -0.911000013, 0.229000002, -0.930999994, 0.284000009, 0.943000019, 0.0120000001, -0.333999991, 0.0109999999, -0.0250000004, 0.999000013, 0.402999997, 0.84799999, -0.344999999, 0.921999991, 0.388000011, -0.00999999978, 0.0399999991, 0.486999989, -0.871999979, -0.296999991, 0.145999998, 0.944000006, -0.374000013, -0.165999994, -0.912, -0.284999996, -0.219999999, 0.933000028,

-0.856000006, -0.317999989, 0.407999992, -0.902999997, 0.382999986, 0.194999993, 0.538999975, -0.728999972, 0.421999991, -0.477999985, 0.878000021, -0.0399999991, 0.764999986, 0.531000018, 0.363999993, -0.518999994, -0.426999986, 0.74000001, 0.66900003, 0.606999993, -0.42899999, -0.104000002, -0.97299999, 0.204999998, -0.660000026, 0.569999993, 0.49000001, -0.0350000001, 0.690999985, 0.722000003, 0.333000004, -0.606000006, 0.722000003, (249) 0; nr of b-factors =2; b-factor order ="ascending"; max b-factor =800; average high b ="user defined"; b-factor averages =4, (15) 1; SAR mode = "high"; B1 mode = "default"; SAR Patient data = "auto"; PNS mode = "moderate"; Gradient mode = "enhanced"; SofTone mode = "no"; Cardiac synchronization ="no"; Heart rate > 250 bpm = "no"; Respiratory compensation ="no"; Navigator respiratory comp = "no"; Flow compensation = "no"; Temporal slice spacing = "default"; NSA = 1; Manual start = "no"; Dynamic study = "no"; dyn stabilization = "no"; Arterial Spin labeling = "no"; Preparation phases = "auto"; Interactive F0 = "no"; SmartPlan survey = "no"; B0 field map = "no"; B1 field map = "no"; MIP/MPR = "no"; Images = " M", (3) " no"; Autoview image = " M"; Calculated images = (4) " no"; Reference tissue = "User defined"; Tissue T1 = 2000; Tissue T2 = 150; Tissue rho = 100; EPI 2D phase correction = "no"; Preset window contrast = "soft"; Reconstruction mode = "immediate"; Save raw data = "no"; Hardcopy protocol = "no"; Ringing filtering = "default"; Geometry correction = "default"; IF_info_seperator = 1634755923; Total scan duration = "05:25.0"; Rel. signal level (%) = 100; Act. TR (ms) = "6500"; Act. TE (ms) = "80"; ACQ matrix M x P = "80 x 78"; ACQ voxel MPS (mm) = "2.00 / 2.03 / 2.00"; REC voxel MPS (mm) = "2.00 / 2.00 / 2.00"; Scan percentage (%) = 98.3871002; Packages = 1; Min. slice gap (mm) = 0;

Diffusion gradient timing DELTA / delta (ms) = "38.8 / 9.5"; EPI factor = 61; WFS (pix) / BW (Hz) = "20.000 / 21.7"; BW in EPI freq. dir. (Hz) = "2638.7"; Min. TR (ms) = "5346"; SPIR offset act./default (Hz) = "200 [135]" SAR / local torso = "< 54 %"; Whole body / level = "< 0.5 W/kg / normal"; B1 rms = "1.18 uT"; PNS / level = "73 % / normal"; Sound Pressure Level (dB) = 20.1907005;

1.5T Philips Sagittal T1W SE (Philips T1.5)

Coronal T2W (Philips T1.5): please change slice orientation in geometry from transverse into coronal:

Inverse recovery: IR (Philips T1.5) please change slice orientation in geometry from transverse into coronal:

DWI: Diffusion weighted imaging (Philips T1.5)

DTI: diffusion tensor imaging please scan axial. (Philips T1.5) We prefer the settings that are explained above for the 3T, however if you will not manage to get nice images, please try the settings below for 1.5T

Simens Magnetom trio – 3T

SIEMENS MAGNETOM TrioTim syngo MR B17

\\USER\Cerebrum\Projekter\SafeBoosC phase ll MRI.\localizer

TA: 0:25 PAT: Off Voxel size: 1.1×1.0×7.0 mm Rel. SNR: 1.00 SIEMENS: gre

Properties

Prio Recon Off

Before measurement

After measurement

Load to viewer On

Inline movie Off

Auto store images On

Load to stamp segments On

Load images to graphic On

segments

Auto open inline display Off

Phase partial Fourier Off

Interpolation On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

PAT mode None

Matrix Coil Mode Auto (CP) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Image Filter Off

Distortion Corr. On

Mode 2D

Unfiltered images Off

Prescan Normalize Off

Normalize Off

Start measurement without

further preparation

Off B1 filter On

Intensity Medium

Wait for user to start Off

Start measurements single

Routine

Slice group 1

Slices 4

Dist. factor 20 %

Position R11.6 A103.7 H2.1

Orientation Transversal

Phase enc. dir. A >> P

Rotation 0.00 deg

Slice group 2

Slices 3

Dist. factor 20 %

Position R11.6 A104.7 F0.1

Orientation Coronal

Phase enc. dir. R >> L

Rotation 0.00 deg

Slice group 3

Slices 5

Dist. factor 30 %


Orientation Sagittal


Rotation 0.00 deg

Phase oversampling 0 %

FoV read 250 mm

FoV phase 100.0 %

Slice thickness 7.0 mm

TR 8.6 ms

TE 4.00 ms

Averages 1

Concatenations 12

Filter Distortion Corr.(2D), Elliptical

filter, B1 filter

Coil elements NHA

Contrast

TD 0 ms

MTC Off

Magn. preparation None

Flip angle 20 deg

Fat suppr. None

Water suppr. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Averaging mode Short term

Reconstruction Magnitude

Measurements 1

Multiple series Each measurement

Resolution

Base resolution 256

Phase resolution 90 %

Unfiltered images Off Raw filter Off

Elliptical filter On

Mode Inplane

Geometry

Multi-slice mode Sequential

Series Interleaved - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Saturation mode Standard

Special sat. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Tim CT mode Off

System

Body Off

NBA Off

NHA On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Positioning mode REF

Table position H

Table position 0 mm

MSMA S - C - T

Sagittal R >> L

Coronal P >> A

Transversal H >> F

Save uncombined Off

Coil Combine Mode Adaptive Combine

AutoAlign ---

Auto Coil Select On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Shim mode Tune up

Adjust with body coil Off

Confirm freq. adjustment Off

Assume Silicone Off

? Ref. amplitude 1H 0.000 V

Adjustment Tolerance Auto

Adjust volume

Position Isocenter


Rotation 0.00 deg

R >> L 350 mm

A >> P 263 mm

F >> H 350 mm

Physio

1st Signal/Mode None

Segments 1 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Tagging None

Dark blood Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Resp. control Off

Inline

1/+


Subtract Off

Liver registration Off

Std-Dev-Sag Off

Std-Dev-Cor Off

Std-Dev-Tra Off

Std-Dev-Time Off

MIP-Sag Off

MIP-Cor Off

MIP-Tra Off

MIP-Time Off

Save original images On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Wash - In Off

Wash - Out Off

TTP Off

PEI Off

MIP - time Off

Sequence

Introduction On

Dimension 2D

Phase stabilisation Off

Asymmetric echo Allowed

Contrasts 1

Bandwidth 320 Hz/Px

Flow comp. No

Allowed delay 0 s - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

RF pulse type Normal

Gradient mode Normal

Excitation Slice-sel.

RF spoiling On

2/+


\\USER\Cerebrum\Projekter\SafeBoosC phase ll MRI.\t1_se_sag_3mm_200mm

TA: 3:48 PAT: Off Voxel size: 1.0×0.8×3.0 mm Rel. SNR: 1.00 SIEMENS: tse

Properties

Prio Recon Off

Before measurement

After measurement

Load to viewer On

Inline movie Off




segments


Start measurement without On

further preparation



Routine

Slice group 1

Slices 31

Dist. factor 10 %


Orientation S > C-5.2 > T-3.4


Rotation 0.00 deg


FoV read 200 mm

FoV phase 100.0 %


TR 550 ms

TE 12 ms

Averages 1

Concatenations 2

Filter Prescan Normalize, Elliptical

filter

Coil elements NHA

Contrast

TD 0.0 ms

MTC Off


Flip angle 90 deg

Fat suppr. None

Water suppr. None

Restore magn. Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Averaging mode Long term


Measurements 1


Resolution

Base resolution 256



Trajectory Cartesian


PAT mode None

Matrix Coil Mode Auto (CP) - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Image Filter Off

Distortion Corr. Off


Prescan Normalize On

Normalize Off

B1 filter Off

Raw filter Off


Mode Inplane

Geometry

Multi-slice mode Interleaved


Special sat. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Tim CT mode Off

System

Body Off

NBA Off

NHA On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -


Table position H

Table position 0 mm

MSMA S - C - T

Sagittal R >> L

Coronal P >> A

Transversal H >> F

Save uncombined Off


AutoAlign ---

Auto Coil Select Default - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Shim mode Tune up



Assume Silicone Off



Adjust volume

Position Isocenter


Rotation 0.00 deg

R >> L 350 mm

A >> P 263 mm

F >> H 350 mm

Physio

1st Signal/Mode None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Dark blood Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Resp. control Off

Inline

Subtract Off

Std-Dev-Sag Off

Std-Dev-Cor Off

Std-Dev-Tra Off

Std-Dev-Time Off

MIP-Sag Off

MIP-Cor Off

MIP-Tra Off

MIP-Time Off

Save original images On

Sequence

Introduction On

Dimension 2D

Compensate T2 decay Off

Reduce Motion Sens. On

Contrasts 1 3/+


Bandwidth 215 Hz/Px

Flow comp. Slice

Allowed delay 60 s - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Define Turbo factor

Turbo factor 1

Echo trains per slice 205

RF pulse type Low SAR


4/+


\\USER\Cerebrum\Projekter\SafeBoosC phase ll MRI.\t2_tse_cor_1,2mm_448_p2

TA: 5:10 PAT: 2 Voxel size: 0.9×0.7×1.2 mm Rel. SNR: 1.00 SIEMENS: tse

Properties

Prio Recon Off

Before measurement

After measurement

Load to viewer On

Inline movie Off




segments



further preparation



Routine

Slice group 1

Slices 110

Dist. factor 20 %


Orientation C > S3.5 > T-1.5

Phase enc. dir. R >> L

Rotation 0.00 deg


FoV read 180 mm

FoV phase 100.0 %


TR 4900 ms

TE 148 ms

Averages 2

Concatenations 7


filter

Coil elements NHA

Contrast

TD 0.0 ms

MTC Off


Flip angle 120 deg

Fat suppr. None

Water suppr. None

Restore magn. Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -



Measurements 1


Resolution

Base resolution 256



Trajectory Cartesian


PAT mode GRAPPA

Accel. factor PE 2

Ref. lines PE 32

Matrix Coil Mode Auto (Triple)

Reference scan mode Self-calibration - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Image Filter Off




Normalize Off

B1 filter Off

Raw filter Off


Mode Inplane

Geometry



Special sat. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Tim CT mode Off

System

Body Off

NBA Off

NHA On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -


Table position H

Table position 0 mm

MSMA S - C - T

Sagittal R >> L

Coronal P >> A

Transversal H >> F

Save uncombined Off


AutoAlign ---


Shim mode Standard



Assume Silicone Off



Adjust volume


Orientation C > S3.5 > T-1.5

Rotation 0.00 deg

F >> H 180 mm

R >> L 180 mm

A >> P 159 mm

Physio


Dark blood Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Resp. control Off

Inline

Subtract Off

Std-Dev-Sag Off

Std-Dev-Cor Off

Std-Dev-Tra Off

Std-Dev-Time Off

MIP-Sag Off

MIP-Cor Off

MIP-Tra Off

MIP-Time Off


Sequence

Introduction On

Dimension 2D

5/+


Compensate T2 decay Off

Reduce Motion Sens. On

Contrasts 1

Bandwidth 254 Hz/Px

Flow comp. No

Allowed delay 60 s

Echo spacing 11.4 ms - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Define Turbo factor

Turbo factor 26

Echo trains per slice 4



6/+


\\USER\Cerebrum\Projekter\SafeBoosC phase ll MRI.\t1_mpr_cor

TA: 4:05 PAT: 2 Voxel size: 0.9×0.8×1.2 mm Rel. SNR: 1.00 SIEMENS: tfl

Properties

Prio Recon Off

Before measurement

After measurement

Load to viewer On

Inline movie Off




segments



further preparation




Normalize Off

B1 filter Off

Raw filter Off


Mode Inplane

Geometry

Multi-slice mode Single shot

Series Ascending - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

System Wait for user to start Off


Routine

Slab group 1

Slabs 1

Dist. factor 50 %


Orientation S > C-5.2 > T-3.4


Rotation 0.00 deg


Slice oversampling 14.3 %

Slices per slab 112

FoV read 200 mm

FoV phase 100.0 %


TR 1900 ms

TE 2.94 ms

Averages 1

Concatenations 1


filter

Coil elements NHA

Contrast

Magn. preparation Non-sel. IR

TI 900 ms

Flip angle 9 deg

Fat suppr. None

Water suppr. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -



Measurements 1


Resolution

Base resolution 256


Slice resolution 100 %

Phase partial Fourier 7/8

Slice partial Fourier Off

Interpolation Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

PAT mode GRAPPA

Accel. factor PE 2

Ref. lines PE 24

Accel. factor 3D 1


Reference scan mode Integrated - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Image Filter Off

Body Off

NBA Off

NHA On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Positioning mode FIX

Table position H

Table position 0 mm

MSMA S - C - T

Sagittal R >> L

Coronal P >> A

Transversal H >> F

Save uncombined Off


AutoAlign ---


Shim mode Tune up

Adjust with body coil On


Assume Silicone Off



Adjust volume

Position Isocenter

Orientation Coronal

Rotation 0.00 deg

R >> L 350 mm

A >> P 263 mm

F >> H 350 mm

Physio


Dark blood Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Resp. control Off

Inline

Subtract Off

Std-Dev-Sag Off

Std-Dev-Cor Off

Std-Dev-Tra Off

Std-Dev-Time Off

MIP-Sag Off

MIP-Cor Off

MIP-Tra Off

MIP-Time Off


Sequence

Introduction On

Dimension 3D

Elliptical scanning Off

Asymmetric echo Allowed


Bandwidth 140 Hz/Px

Flow comp. No

Echo spacing 9 ms - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -



Excitation Non-sel.

RF spoiling On

8/+


\\USER\Cerebrum\Projekter\SafeBoosC phase ll MRI.\ep2d_diff_orth_p2_tra

TA: 1:31 PAT: 2 Voxel size: 1.2×1.2×4.0 mm Rel. SNR: 1.00 SIEMENS: ep2d_diff

Properties

Prio Recon Off

Before measurement

After measurement

Load to viewer On

Inline movie Off




segments



further preparation



Routine

Slice group 1

Slices 28

Dist. factor 30 %


Orientation T > S4.5 > C2.9


Rotation 0.00 deg


FoV read 230 mm

FoV phase 100.0 %


TR 4700 ms

TE 102 ms

Averages 4

Concatenations 1

Filter Raw filter, Distortion

Corr.(2D), Prescan Normalize

Coil elements NHA

Contrast

MTC Off


Fat suppr. Fat sat. - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -



Delay in TR 0 ms

Resolution

Base resolution 192




PAT mode GRAPPA

Accel. factor PE 2

Ref. lines PE 24


Reference scan mode Separate - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Distortion Corr. On

Mode 2D



Raw filter On

Intensity Weak

Slope 25

Elliptical filter Off

Hamming Off

Geometry



Special sat. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

System

Body Off

NBA Off

NHA On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -


Table position H

Table position 0 mm

MSMA S - C - T

Sagittal R >> L

Coronal P >> A

Transversal H >> F


AutoAlign ---


Shim mode Standard



Assume Silicone Off



Adjust volume



Rotation 0.00 deg

R >> L 230 mm

A >> P 230 mm

F >> H 145 mm

Physio


Resp. control Off

Diff

Diffusion mode Orthogonal

Diff. weightings 2

b-value 1 0 s/mm²

b-value 2 800 s/mm²

Diff. weighted images Off

Trace weighted images On

Average ADC maps On

Individual ADC maps Off

FA maps Off

Mosaic Off

Tensor Off

Noise level 40

Diff. directions 3

Sequence

Introduction On

Bandwidth 1184 Hz/Px

Free echo spacing Off

Echo spacing 0.93 ms - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

EPI factor 192


Gradient mode Fast

9/+


\\USER\Cerebrum\Projekter\SafeBoosC phase ll MRI.\ep2d_diff_mddw_30_p2

TA: 9:28 PAT: 2 Voxel size: 2.0×2.0×2.0 mm Rel. SNR: 1.00 SIEMENS: ep2d_diff

Properties

Prio Recon Off

Before measurement

After measurement

Load to viewer On

Inline movie Off




segments



further preparation



Routine

Slice group 1

Slices 49

Dist. factor 30 %




Rotation 0.00 deg


FoV read 250 mm

FoV phase 100.0 %


TR 5900 ms

TE 81 ms

Averages 3

Concatenations 1

Filter Prescan Normalize

Coil elements NHA

Contrast

MTC Off


Fat suppr. Fat sat. - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -



Delay in TR 0 ms

Multiple series Off

Resolution

Base resolution 122



Interpolation Off - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

PAT mode GRAPPA

Accel. factor PE 2

Ref. lines PE 24


Reference scan mode Separate - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -



Raw filter On

Elliptical filter Off

Hamming Off

Geometry



Special sat. None - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

System

Body Off

NBA Off

NHA On - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Positioning mode FIX

Table position H

Table position 0 mm

MSMA S - C - T

Sagittal R >> L

Coronal P >> A

Transversal H >> F


AutoAlign ---


Shim mode Standard



Assume Silicone Off



Adjust volume



Rotation 0.00 deg

R >> L 250 mm

A >> P 250 mm

F >> H 127 mm

Physio


Resp. control Off

Diff

Diffusion mode MDDW

Diff. weightings 2

b-value 1 0 s/mm²

b-value 2 800 s/mm²

Diff. weighted images On

Trace weighted images On

Average ADC maps On

Individual ADC maps Off

FA maps On

Mosaic On

Tensor On

Noise level 30

Diff. directions 30

Sequence

Introduction On

Bandwidth 1518 Hz/Px

Free echo spacing Off

Echo spacing 0.74 ms - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

EPI factor 122


Gradient mode Fast 10/+


Table of contents

\\USER Cerebrum

Projekter

SafeBoosC phase ll MRI. localizer

t1_se_sag_3mm_200mm

t2_tse_cor_1,2mm_448_p2

t1_mpr_sag

ep2d_diff_orth_p2_tra

ep2d_diff_mddw_30_p2

SafeBoosC phase II - SOP - Brain MRI

Version 1.0 29

sop: brain mri - rigshospitalet · sop: brain mri author(s) date changes approved by cornelia...

Documents