specialty chemicals and pharma intermediates
TRANSCRIPT
Specialty Chemicals and Pharma Intermediates
The demand for specialty chemicals is increasing many fold due to the rising market of the pharmaceutical chemicals and fine chemicals. Chemcon Speciality Chemicals Pvt. Ltd. strives to be a market leader in domestic and global market to satiate the world wide demand for specialty chemicals and pharma intermediates like Chloromethyl Isopropyl Carbonate (CMIC) and Hexamethyl Disilazane (HMDS) which have a variety of applications and uses.
Specialty chemicals are the chemicals that enhance performance of many other chemical
products that provide an array of effects. They come in different forms like material additives,
ingredients in a formulation or mixture or intermediates that are used to manufacture other
products like adhesives, construction chemicals, elastomers, polymers, agrichemicals,
lubricants, etc. Specialty chemicals and pharma intermediates are prepared based on their
functions. Thus these can be variety of formulations or single-chemical entities that are used in
the enhancement of the functions of various products. Among these, many handy pharma
intermediates Chloromethyl Isopropyl Carbonate (CMIC) and Hexamethyl Disilazane (HMDS)
are widely used chemicals in the industry. The HMDS Manufacturers across the globe, due to
its many applications and uses, especially find a potential market to work in.
Chemcon Speciality Chemicals Pvt. Ltd. is one of the global leading specialty firms that
produce a range of specialty chemicals: pharma intermediates. Amongst which, HMDS and
CMIC are important products provided by Chemcon.
Hexamethyl Disilazane (HMDS)
It is a major organ silicon compound which is colorless in nature. This liquid is a precursor to
popular bases and is a reagent. It is a popular ingredient in different types of organic synthesis
and organometallic chemistry. For handling HMDS, it is required to follow air-free techniques.
Applications and Uses:
1. Used as an excellent adhesive promoter
2. Widely used in the paints and coatings industry
3. Used instead of the critical point drying in Electron Microscopy
4. Used in the semiconductor industry due to its ability to supplement the adhesion of
photoresist on silicon surfaces.
5. Used as an excellent agent in silylation of alcohols, phenols, amines, and acids.
6. Used as a lubricant, coupling agent, deactivator for chromatographic support
materials, chemical intermediate, etc.
Chloromethyl Isopropyl Carbonate (CMIC)
A lot of companies use this pharma intermediate or specialty chemical for curing chronic
diseases like AIDS and hepatitis B. A popular drug named tenofovir is manufactured using this
specialty chemical. The rising importance of CMIC in the field of medicine is due to its 99%
clarity assurance and its use to prepare tenofovir. Tenofovir disoproxil hemifumarate salt is
basically prepared using dealkylating (R)-9-[2-(Diethyl phosphonomethoxy) propyl] adenine.
To get a crystallized tenofovir in its stable form, Chloromethyl isopropyl carbonate is used,
where it is used to condense tenofovir during the latter’s initial phase of manufacture.
Properties of CMIC
1. It has a purity of approximately 98%,
2. Its density ranges from 1.1390 to 1.1430
3. It is easily soluble in chloroform.
4. Its 147.5 °C at 760 mmHg and its flash point is 50 degree Celsius.
These properties of CMIC are the essential features that build up a characteristic CMIC product
that have important applications.
At Chemcon, we produce Chloromethyl Isopropyl Carbonate (CMIC) at 99.9% purity
throughout its production. Thus we stand as one of the best quality manufacturers of CMIC
world-wide. Moreover, the other important specialty chemical, HMDS is also produced with a
superior quality, making us one of the best HMDS manufactures In Gujarat on an
international specialty chemicals platform.
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