splat! incidence mortality rate correlation communicable non-communicable epidemiology aetiology...
TRANSCRIPT
SPLAT!
Incidence
Mortality rate
Correlation
Communicable
Non-communicable
Epidemiology
Aetiology
Relative risk
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Biology(16 - 18)
Biology(16 - 18)
Disease & Lifestyle Cancer and Coronary
heart disease
Disease & Lifestyle Cancer and Coronary
heart disease
LO
• Analyse and interpret data to provide evidence, recognising correlations and causal relationships associated with cancer and coronary heart disease.
How are data on disease interpreted and analysed?
• Epidemiology- study of pattern and incidence of disease. Aim is to find means of control and prevention.
Conclusions:•Risk of lung cancer decreases the sooner you quit smoking•Risk of lung cancer increases with age•Difference in risk is less extreme between 45 and 55. After 55 larger difference between groups EXCEPT between those who still smoke and those who quit at 55.
Looking at data critically• Has the right factor been measured and have
the right questions been asked?• How was the data gathered, were teh
methods reliable and was the right apparatus used?
• Do those collecting the data have a vested interest in the outcome of the research?
• Has the study been repeated, with the same results and conclusions, by other people?
• Are there still unanswered questions?
1..10 11...20 21...30 31...40 40+0
5
10
15
20
25
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40
1-4 years since quitting30+ years since quitting
1. State 2 correlations shown.
2. Explain why the informatio0n provided does not show a causal relationship between the correlations you have identified.
3. The y-axis of the bar chart is labelled ‘Relative risk of lung cancer’. Explain what this means.
Cigarettes smoked per day before giving up smoking.
Rela
tive
risk
of lu
ng c
ance
r
A tumour (neoplasm) is tissue composed of cells that have grown abnormally
In normal tissue, mitosis is a controlled process such that growth is regulated
When the regulatory processes that control cell division break down, cells divide uncontrollably and
form tumours (abnormal masses/neoplasms)
Tumours may be benign or malignant; it is the malignant tumours that are classified as cancers
Cancer and CHD
What are the factors that contribute to the incidence of cancer?
Individual susceptibility to cancer is the result of a combination of different factors
The risk of developing cancer depends on:
• Heredity (genetic makeup)• Environmental exposure to carcinogens• Personal lifestyleA carcinogen is an agent that increases the
likelihood of cancer developing and includes certain chemicals, radiation and some viruses
Environmentalchemicals and toxins
Tobacco and tobacco smoke carcinogens
Genetic factors
Viruses
Radiation e.g., UV radiation and X-rays
Diet and alcohol
Physical activity
Coronary heart disease
• CHD causes around 114,000 deaths a year in the UK and is the most common cause of premature death
• Although death rates from CHD in the UK have been falling, they have not decreased as fast as in some other countries
What is CHD
• Coronary heart disease (CHD) is a narrowing of the coronary arteries that supply blood and oxygen to the heart
• Coronary heart disease usually results from the build up of fatty material in the walls of the arteries; this is known as atherosclerosis and is usually accompanied by a loss of elasticity of the arteries involved
Risk factorsThere are many factors which increase the risk of coronary
heart disease; some of these risks are controllable, e.g. diet, whereas others are unavoidable and are based on genetics and advancing age.
• Family history• Age (65 and over)• Male gender• Tobacco smoking and Passive smoking• High blood pressure• High cholesterol levels in the blood• Poor diet that is high in saturated fats• Diabetes mellitus• Overweight and Obesity• Lack of physical activity and exercise
TASK
Complete sheet 1.9 and the PPQ.