stem cells in the treatment of infertility

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Email: [email protected], Mob: +91 9811011690 W: StemGenn.com

Stem cells in the treatment of Infertility

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http://StemGenn.com/

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Website : www.stemgenn.com | Email : [email protected] | Phone : +91 9910596674

Stem cells in the treatment of InfertilityWhat is infertility?

Infertility refers to biological inability of a person to conceive or a female who is not able to carry the pregnancy.

In general, infertility refers to a couple that has failed to conceive after 12 months of regular sexual intercourse without the use of contraception.

Studies indicate that slightly over half of all cases of infertility are a result of female conditions, while the rest are caused by either sperm disorders or unidentified factors.

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Stem cells in the treatment of InfertilityAccording to The Mayo Clinic, USA:

• About 20% of cases of infertility are due to a problem in the man.• About 40% to 50% of cases of infertility are due to a problem in the

woman.• About 30% to 40% of cases of infertility are due to problems in

both the man and the woman.

According to the Department of Health and Human Services, USA, approximately 10% to 15% of couples in the USA are infertile. Many cases of apparent infertility are treatable. Infertility may have a single cause in one of the partners, or it could be the result of a combination of factors.

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Once a couple diagnosed with infertility, the investigation for possible treatments get started. In recent years, various advancements have been made in assisted reproduction treatment and now more than 80% of couples experiencing infertility issues can conceive a child .

Stem cells are considered as new therapeutic agents for the treatment of infertility due to their widely available sources and high differentiation potential. The article below focuses on various aspects of stem cells usage for the treatment of infertility.

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Stem cells in the treatment of Infertility Use of stem cells in Infertility:Since 2004, the research on the usage of stem cells for the treatment of infertility has been surrounded by hype.

As per the conventional theory, the eggs woman carries since her birth are the one which are involved in the reproduction process however some scientists claim that by using stem cells these eggs can be created in lab and prove as a blessing for infertile women’s, such as those who entered the menopause stage. However the researchers at the Department of Chemistry and Molecular Biology at the University of Gothenburg tried to create egg cells but not succeeded. This creates uncertainty about the use of stem cells for the creation of new egg cells.

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Further, together with Outi Hovatta's research group at Karolinska Institute and Jan-Åke Gustafsson's research team at the University Houston in the United States, experiments were carried out on mice, which shows that the only eggs, female mice have are the ones which they carries since birth. This experiment shows that use of stem cells in infertility is unrealistic but also clinics and clinicians should focus on using the eggs the women have had since birth in treating infertility.

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Till now, one of the best known techniques for treating infertility includes In vitro fertilization (IVF). It is a process which involves removing an egg from a woman's ovaries and fertilizing it with sperm in a lab. The egg once fertilized referred to as an embryo, is implanted to a woman's womb, to grow and develop into a pregnancy.

The picture in the next slide shows the whole process of In vitro fertilization.

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A leading expert in the field, Cambridge University's Professor Roger Pederson, said the latest stem cell research would not be possible without IVF. Embryos used in the studies were left over from IVF treatment and donated by consenting couples. "This is all a legacy of the 25 years of IVF," he said.

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It is predicted that in future everybody who is infertile can be helped, by using artificially created sperms and eggs. However, there is a huge potential in interaction of stem cell technology with the reproductive functions and the infertility treatment. Already, experiments on mice have indicated it is possible to turn stem cells - the body's unprogrammed 'master' cells - into sperm or eggs. However clinical trials are under process for human treatment .As per the researchers, In the future, they will be able to take the cells and create the equivalent sperms and egg cells but it is a matter of time as a lot of work need to be done to show the efficiency and safety of these procedures.

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StemGenn Therapeutics is one of the centre providing solution to infertility problems using the stem cell therapies.

Infertility issues in both male and female include Oligospermia, erectile dysfunction, recurrent IVF failure, endometriosis, Asherman syndrome etc.


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About StemGenn TherapeuticsStemGenn Therapeutics is a leading Cell therapy & Regenerative medicine services company that supports the development and commercialization of cellular therapies and stem cell research.

StemGenn provides cGMP-compliant cell manufacturing and consulting services that address regulatory, financial, technical, process, training and quality system strategies.

Services include a full spectrum of support and consulting related to process and product development, validation, due diligence evaluations, tissue collection, processing, and storage, product manufacturing, distribution and transportation.


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Why StemGenn Therapeutics ?

• As Stem cell have inherent properties to self renew and differentiation into other cell types. They are multi potent and found within our body.• No side effects: as it's found in patient's own tissues or

blood, chances of rejection and infection is negligible.• World class clinicians and experts from Regenerative

Medicine.• Cost Effectiveness: autologous stem cell transplant is

very much affordable.• Non- Surgical Procedure & convenient.• Proven Results.


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The Management & Medical Advisory Board

• Mr. Prabhu Mishra : CEO, Co-Founder• Ms. Richa Jha : MD, Co-Founder• Ms. Shreyashi Gangopadhyay: Director- Business

Development• Dr. Sharda Jain : Chairman- Global StemGenn• Dr. H S Bedi :Director- Cardio Vascular, CMC

Ludhiana• Dr. Satish Totey: Stem Cell Scientist over 35 years

Experiences.• Dr. Roopam Jain: MD Transfusion Medicine, Assoc.

Profeesor.


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StemGenn Therapeutics Services• Stem cell consulting services.• Stem cell & cord blood bank set up• Regulatory, financial & compliances consultancy• Technical & scientific support for Regenerative Medicine• Stem cell & Bone Marrow Transplant program• Stem cell Therapy • Anti ageing program• Sports Injury and Arthritis : autologous cell implant• Neuro degenerative diseases & Neuro Rehabilitation & Regenerative Therapy.• Business Consulting.• PRP Therapy for Hair Regeneration• Tissue engineering program for Diabetic foot & Maxillofacial application.• Dedicated to services of stem cell therapy & Regenerative Medicine( Repair, Regenerate & Restore).


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References :

http://www.sciencedaily.com/releases/2015/02/150204075326.htm

http://www.figo.org/news/stem-cell-treatment-infertility-long-way-0014879

http://www.medicaldaily.com/infertility-treatment-may-soon-include-artificial-sperm-egg-cells-derived-stem-cells-315622

stem cells in the treatment of infertility

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