strmix contributor training - indiana · microsoft powerpoint - strmix contributor training author:...
TRANSCRIPT
![Page 1: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/1.jpg)
![Page 2: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/2.jpg)
![Page 3: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/3.jpg)
![Page 4: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/4.jpg)
![Page 5: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/5.jpg)
Electropherogram
![Page 6: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/6.jpg)
Loci (Locus): segment of DNA
![Page 7: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/7.jpg)
Allele
6, 9.3
16, 19
![Page 8: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/8.jpg)
Genotype: set of alleles
[22, 25]
[12, 12]
![Page 9: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/9.jpg)
![Page 10: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/10.jpg)
How do we make these determinations?
![Page 11: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/11.jpg)
As long as we have been using the CE platform, we have known certain things about the way DNA behaves:
possible genotypes of the individual contributors
![Page 12: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/12.jpg)
![Page 13: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/13.jpg)
![Page 14: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/14.jpg)
![Page 15: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/15.jpg)
![Page 16: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/16.jpg)
![Page 17: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/17.jpg)
![Page 18: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/18.jpg)
![Page 19: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/19.jpg)
![Page 20: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/20.jpg)
![Page 21: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/21.jpg)
![Page 22: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/22.jpg)
A short video explaining STRmix is available at:
https://strmix.esr.cri.nz/
![Page 23: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/23.jpg)
![Page 24: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/24.jpg)
![Page 25: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/25.jpg)
![Page 26: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/26.jpg)
Y
Y
Y
Y
STRmixTM
Weightings0.160.140.050.480.120.0030.00030.040.001
![Page 27: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/27.jpg)
![Page 28: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/28.jpg)
![Page 29: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/29.jpg)
![Page 30: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/30.jpg)
![Page 31: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/31.jpg)
![Page 32: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/32.jpg)
![Page 33: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/33.jpg)
![Page 34: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/34.jpg)
• In an LR: the numerical value WILL change if you change the propositions
• For this reason, we want to explain how we set those propositions, and how important case information can be in this process
![Page 35: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/35.jpg)
Constructing Propositions
![Page 36: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/36.jpg)
Likelihood Ratio
Probability
EvidenceIF/GIVEN
Prosecution Explanation
Defense Explanation
![Page 37: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/37.jpg)
![Page 38: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/38.jpg)
• If all parties agree that the DNA profile originated from the same individual(s), the likelihood ratio would equal 1. A likelihood ratio of 1 is uninformative.
![Page 39: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/39.jpg)
![Page 40: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/40.jpg)
![Page 41: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/41.jpg)
![Page 42: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/42.jpg)
![Page 43: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/43.jpg)
![Page 44: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/44.jpg)
Likelihood Ratio (or 1/LR) Verbal equivalent
1 ≤ LR< 10 uninformative
10 ≤ LR < 100 provides weak support
100 ≤ LR < 1000 provides moderate support
1000 ≤ LR provides strong support
![Page 45: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/45.jpg)
��������|� ��������� � ���� ���������|������
![Page 46: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/46.jpg)
![Page 47: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/47.jpg)
![Page 48: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/48.jpg)
![Page 49: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/49.jpg)
![Page 50: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/50.jpg)
![Page 51: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/51.jpg)
![Page 52: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/52.jpg)
• DNA Testimony not allowed
• New York had not performed an internal validation
![Page 53: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/53.jpg)
![Page 54: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/54.jpg)
• Yes
![Page 55: STRmix Contributor Training - Indiana · Microsoft PowerPoint - STRmix Contributor Training Author: johnson7457 Created Date: 12/6/2017 9:17:20 AM](https://reader034.vdocuments.net/reader034/viewer/2022042809/5f95f0c261c43e37007ab544/html5/thumbnails/55.jpg)