study program 2018/2019 subjects of the 3-4. semesters … · 6 investigation of the behavior of...
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UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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University of Pécs Faculty of Pharmacy
PHARMACY Major
STUDY PROGRAM 2018/2019
Subjects of the 3-4. semesters
(obligatory subjects and criterion requirements)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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3rd semester
OPA-FZ2-T ____ Physical Chemistry 2 ________________________________________________________________________ 3
OPA-KD1-T ____ Colloidics 1 _______________________________________________________________________________ 5
OPA-V1E-T ____ Organic Chemistry 1 - Theory _________________________________________________________________ 7
OPA-V1G-T ____ Organic Chemistry 1 - Practice _______________________________________________________________ 10
OPO-AI2-T _____ Human Anatomy, Histology and Embriology 2 __________________________________________________ 12
OPO-G1E-T ____ Pharmacobotany 1 - Theory _________________________________________________________________ 14
OPO-G1G-T ____ Pharmacobotany 1 - Practice _________________________________________________________________ 16
OPO-H1E-T ____ Human Physiology 1 - Theory ________________________________________________________________ 18
OPO-H1G-T ____ Human Physiology 1 - Practice _______________________________________________________________ 23
ATT3-T _______ Physical Education 3 _______________________________________________________________________ 27
4th semester
OPA-M1E-T ____ Instrumental Analysis - Theory _______________________________________________________________ 28
OPA-M1G-T ___ Instrumental Analysis - Practice ______________________________________________________________ 30
OPA-V2E-T ____ Organic Chemistry 2 - Theory ________________________________________________________________ 32
OPA-V2G-T ____ Organic Chemistry 2 - Practice _______________________________________________________________ 36
OPG-GI1-T _____ Basic Principles of Pharmacy ________________________________________________________________ 38
OPO-G1B-T ____ Pharmaceutical Biochemistry 1 _______________________________________________________________ 40
OPO-G2E-T ____ Pharmacobotany 2 - Theory _________________________________________________________________ 42
OPO-G2G-T ____ Pharmacobotany 2 - Practice _________________________________________________________________ 45
OPO-H2E-T ____ Human Physiology 2 - Theory ________________________________________________________________ 47
OPO-H2G-T ____ Human Physiology 2 - Practice _______________________________________________________________ 53
ATT4-T _______ Physical Education 4 _______________________________________________________________________ 58
OPR-HUF-O-T __ Final Examination in Hungarian Pharmaceutical Terminology - oral __________________________________ 59
OPR-HUF-W-T _ Final Examination in Hungarian Pharmaceutical Terminology - written _______________________________ 60
OPR-SG1-T ____ Professional Practice 1 _____________________________________________________________________ 61
ATT1-2-3-4-5 ___ Physical Education courses 1-2-3-4-5 __________________________________________________________ 63
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPA-FZ2-T PHYSICAL CHEMISTRY 2
Course director: DR. GÁBOR LENTE, professor
Faculty of Natural Sciences - Department of General and Physical Chemistry
3 credit ▪ midsemester grade ▪ Basic subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 42 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 4 – 36 Prerequisites: OPA-FZ1-T completed
Topic
The students completing the course will get experience in carrying out basic physical chemical measurements. They will learn the ways
of handling instruments, taking notes, evaluating experimentally taken data. Before the practice each student obtains an experimental
task to be solved. In home reading they refresh the theoretical back ground and study the instructions. Before beginning the laboratory
work they complete a short test to prove their level of understanding the theory and practice of the task to be solved. They work alone
following the written instructions and guidelines of the instructor. The data, calculations, graphs, tables and conclusions are introduced
into a carefully prepared note book. The tasks are taken from chapters of physical chemistry studied in course Physical chemistry I:
Thermo dynamics, reaction kinetics, electro chemistry, equilibrium, properties of solutions, determination of indicator exponents.
Different instruments like electrochemical work stations, spectro photometers, calorimeters, gas volume measurements, conductometric apparatus, pH meter and other basic „small” laboratory equipment are used.
Conditions for acceptance of the semester
Maximum of 10 % absence of practices allowed.
Mid-term exams
Two tests per semester will be performed.
Making up for missed classes
One week absence can be tolerated if the experiment is performed in a supplementary time (last week)
Reading material
- Obligatory literature
P.J. SINKO: Martin’s Physical Pharmacy and Pharmaceutical Sciences, Lippincott Williams & Wilkins, Philadelphia, 2011
P. Atkins, J. de Paula: Physical Chemistry, 8th edition, Oxford University Press 2006, ISBN 9780198700722
- Literature developed by the Department
The description of the experimental work is given in the home page of the department
- Notes
The description of the experimental work is given in the home page of the department
Laboratory manual downloaded from the web site of the Dept. for General and Physical Chemistry of Faculty of Sciences at the
University of Pécs
- Recommended literature
D. Freifelder: Physical Chemistry for Students of Biology and Chemistry, Science Books International Inc. ISBN 0 86720-002-2
Lectures
Practices
1 Determination of solubility, calculation of the differential dissolution heat
2 Determination of solubility, calculation of the differential dissolution heat
3 Determination of solubility, calculation of the differential dissolution heat
4 Investigation of the behavior of terner (three component) systems, preparation solubility triangle diagram
5 Investigation of the behavior of terner (three component) systems, preparation solubility triangle diagram
6 Investigation of the behavior of terner (three component) systems, preparation solubility triangle diagram
7 Investigation of the behavior Reaction heat measurement using adiabatic calorimeter
8 Investigation of the behavior Reaction heat measurement using adiabatic calorimeter
9 Investigation of the behavior Reaction heat measurement using adiabatic calorimeter
10 Investigation of kinetics of hydrolysis with conductometryc measurements
11 Investigation of kinetics of hydrolysis with conductometryc measurements
12 Investigation of kinetics of hydrolysis with conductometryc measurements
13 Investigation of decomposition kinetics of a drug molecule
14 Investigation of decomposition kinetics of a drug molecule
15 Investigation of decomposition kinetics of a drug molecule
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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16 Investigation of homogeneous catalysis (oxidation of ascorbic acid)
17 Investigation of homogeneous catalysis (oxidation of ascorbic acid)
18 Investigation of homogeneous catalysis (oxidation of ascorbic acid)
19 Study of drug dissolution kinetics from pharmaceutical pills using spectrophotometric method
20 Study of drug dissolution kinetics from pharmaceutical pills using spectrophotometric method
21 Study of drug dissolution kinetics from pharmaceutical pills using spectrophotometric method
22 Potentiometry, pH measurement, investigation of selectivity of ion selective electrodes, measurement of redox potential.
23 Potentiometry, pH measurement, investigation of selectivity of ion selective electrodes, measurement of redox potential.
24 Potentiometry, pH measurement, investigation of selectivity of ion selective electrodes, measurement of redox potential.
25 Measurement of conductivity in electrolytes
26 Measurement of conductivity in electrolytes
27 Measurement of conductivity in electrolytes
28 Investigation of kinetics of electrode processes, cyclic voltammetry, current - electrode potential curves, Cottrell form, Tafel’s equation
29 Investigation of kinetics of electrode processes, cyclic voltammetry, current - electrode potential curves, Cottrell form, Tafel’s equation
30 Investigation of kinetics of electrode processes, cyclic voltammetry, current - electrode potential curves, Cottrell form, Tafel’s
equation
31 Determination of solubility products using potentiometric measurements
32 Determination of solubility products using potentiometric measurements
33 Determination of solubility products using potentiometric measurements
34 Determination of dissociation coefficient of color indicators using spectrophotometric method.
35 Determination of dissociation coefficient of color indicators using spectrophotometric method.
36 Determination of dissociation coefficient of color indicators using spectrophotometric method.
37 Computer modeling chemical reactions
38 Computer modeling chemical reactions
39 Computer modeling chemical reactions
40 Determination of diffusion coefficients
41 Determination of diffusion coefficients
42 Determination of diffusion coefficients
Seminars
Exam topics/questions
There is no exam to be taken for passing the laboratory practice
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Kiss András (KIAIAET.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPA-KD1-T COLLOIDICS 1
Course director: DR. BARNA SZILÁRD KOVÁCS, associate professor
Faculty of Natural Sciences - Department of General and Physical Chemistry
2 credit ▪ semester exam ▪ Basic subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – not limited Prerequisites: OPA-AM1-T completed
Topic
Learning about the types, structure, stability, chemical and physical-chemical properties and about laws of interaction of colloidal systems.
Conditions for acceptance of the semester
-
Mid-term exams
Two written tests (after the 5th and 10th lessons) should be completed (min. 50%) during the semester.
Making up for missed classes
-
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
D. J. Shaw: Introduction to Colloid and Surface Chemistry, 4th ed. (or later), Butterworth-Heinemann, Oxford 1992.,
D. F. Evans, H. Wennerström: The Colloidal Domain: Where Physics, Chemistry, Biology and Technology Meet, 2nd ed., Wiley-VCH, New York 1999.
D. H. Everett: Basic Principles of Colloid Science, RSC, London 1988.
Lectures
1 The colloidal state
Dr. Kovács Barna Szilárd
2 Classification of colloidal systems
Dr. Kovács Barna Szilárd
3 The structure of interfaces
Dr. Kovács Barna Szilárd
4 Interfacial phenomena.
Dr. Kovács Barna Szilárd
5 Surface tension.
Dr. Kovács Barna Szilárd
6 Gas/liquid interface.
Dr. Kovács Barna Szilárd
7 Interface of solution, phase boundary
Dr. Kovács Barna Szilárd
8 Liquide/liquide interfaces
Dr. Kovács Barna Szilárd
9 Solid/liquide interface
Dr. Kovács Barna Szilárd
10 Capillary condensation. Wetting, wetting materials.
Dr. Kovács Barna Szilárd
11 Adsorption phenomenon
Dr. Kovács Barna Szilárd
12 Heat of adsorption, adsorption equations
Dr. Kovács Barna Szilárd
13 Adsorption isotherms (Freundlich, Langmuir, Langmuir-Hückel, BET),
Dr. Kovács Barna Szilárd
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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14 Adsorption hysteresis
Dr. Kovács Barna Szilárd
15 Electric double-layer, electrokinetic potential
Dr. Kovács Barna Szilárd
16 Electrokinetic phenomena
Dr. Kovács Barna Szilárd
17 Properties of dispersed systems: distribution, morfology, degree of dispersity
Dr. Kovács Barna Szilárd
18 Stability of colloidal systems, parameters that affect the stability
Dr. Kovács Barna Szilárd
19 Aerosols, foams
Dr. Kovács Barna Szilárd
20 Emulsions, suspensions
Dr. Kovács Barna Szilárd
21 Reology, properties and methodology.
Dr. Kovács Barna Szilárd
22 Macromolecular colloids
Dr. Kovács Barna Szilárd
23 Properties, examination methods of macromolecular colloids
Dr. Kovács Barna Szilárd
24 Association colloids
Dr. Kovács Barna Szilárd
25 Micelle formation
Dr. Kovács Barna Szilárd
26 Parameters that affect the micelle formation
Dr. Kovács Barna Szilárd
27 Liposomes
Dr. Kovács Barna Szilárd
28 Langmuir Blodget films, LB technique.
Dr. Kovács Barna Szilárd
Practices
Seminars
Exam topics/questions
The colloidal state, classification of colloidal systems
The structure of interfaces, interfacial phenomena. Surface tension.
Gas/liquid interface. Interface of solution, phase boundary, liquide/liquide interfaces
Solid/liquide interface, capillary condensation. Wetting, wetting materials.
Adsorption phenomenon, heat of adsorption, adsorption equations, adsorption isotherms (Freundlich, Langmuir, Langmuir-Hückel, BET), adsorption hysteresis.
Electric double-layer, electrokinetic potential, electrokinetic phenomena.
Properties of dispersed systems: distribution, morfology, degree of dispersity. Stability of colloidal systems, parameters that affect the stability
Aerosols, foams, emulsions, suspensions.
Reology, properties and methodology.
Macromolecular colloids, properties, examination methods.
Association colloids, micelle formation, parameters that affect the micelle formation, liposomes, Langmuir Blodget films, LB technique.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPA-V1E-T ORGANIC CHEMISTRY 1 - THEORY
Course director: DR. TAMÁS KÁLAI, professor
Department of Organic and Pharmacological Chemistry
3 credit ▪ semester exam ▪ Basic subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 42 lectures + 0 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 2 – 80
Prerequisites: OPA-L1E-T completed + OPA-AM1-T completed + OPA-V1G-T parallel
Topic
This subject is a part of chemistry basics. Its aim is to present the nomenclature, structure, physical and chemical properties, synthesis,
reaction mechanisms and application of organic compounds.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Students can venture upon the accomplishment of written test two times.
Making up for missed classes
Students have to contact the lecturer of the subject.
Reading material
- Obligatory literature
John McMurry, Eric Simanek: Fundamentals of Organic Chemistry, 6th ed., Thomson Brooks, Belmont, 2007.
- Literature developed by the Department
- Notes
- Recommended literature
T. W. Graham Solomons: Organic Chemistry, 7th edition, Wiley and Sons, New York, 2000.
William H. Brown: Organic Chemistry, Saunders College Publishing, Fort Worth, 1995.
Lectures
1 The nature of chemical bonds; Hybridization; Polar covalent bonds, electronegativity; Acids and bases: Bronsted-Lowry and Lewis definition
Dr. Kálai Tamás
2 The nature of chemical bonds; Hybridization; Polar covalent bonds, electronegativity; Acids and bases: Bronsted-Lowry and Lewis definition
Dr. Kálai Tamás
3 The nature of chemical bonds; Hybridization; Polar covalent bonds, electronegativity; Acids and bases: Bronsted-Lowry and Lewis definition
Dr. Kálai Tamás
4 The system of organic compounds, functional groups, reaction mechanisms.
Dr. Kálai Tamás
5 The system of organic compounds, functional groups, reaction mechanisms.
Dr. Kálai Tamás
6 Spectrometric structure identification of organic compounds.
Dr. Kálai Tamás
7 Isomerism and stereochemistry: constitutional isomerism, conformation, cis-trans isomerism, chirality, optical activity, specific
rotation, enantiomers and diastereomers, relative and absolute configuration.
Dr. Kálai Tamás
8 Isomerism and stereochemistry: constitutional isomerism, conformation, cis-trans isomerism, chirality, optical activity, specific
rotation, enantiomers and diastereomers, relative and absolute configuration.
Dr. Kálai Tamás
9 Isomerism and stereochemistry: constitutional isomerism, conformation, cis-trans isomerism, chirality, optical activity, specific rotation, enantiomers and diastereomers, relative and absolute configuration.
Dr. Kálai Tamás
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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10 Alkanes and cycloalkanes; Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, conformation.
Dr. Kálai Tamás
11 Alkanes and cycloalkanes; Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, conformation.
Dr. Kálai Tamás
12 Alkanes and cycloalkanes; Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties,
conformation.
Dr. Kálai Tamás
13 Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and
alkynes.
Dr. Kálai Tamás
14 Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and
alkynes.
Dr. Kálai Tamás
15 Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and
alkynes.
Dr. Kálai Tamás
16 Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids.
Dr. Kálai Tamás
17 Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids.
Dr. Kálai Tamás
18 Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids.
Dr. Kálai Tamás
19 Aromatic compounds: the structure of benzene, Hückel’s rule. Electrophilic aromatic substitution reactions. Substituent effects in electrophilic aromatic substitution. Oxidation and reduction of aromatic compounds; Polycyclic compounds.
Dr. Kálai Tamás
20 Aromatic compounds: the structure of benzene, Hückel’s rule. Electrophilic aromatic substitution reactions. Substituent effects in electrophilic aromatic substitution. Oxidation and reduction of aromatic compounds; Polycyclic compounds.
Dr. Kálai Tamás
21 Aromatic compounds: the structure of benzene, Hückel’s rule. Electrophilic aromatic substitution reactions. Substituent effects in electrophilic aromatic substitution. Oxidation and reduction of aromatic compounds; Polycyclic compounds.
Dr. Kálai Tamás
22 Alkyl halides: the character of C-X bonds, synthesis and reactions of alkyl halides; Nuclephilic substitution reactions, SN1, SN2, eliminations; Organic halides in the environment.
Dr. Kálai Tamás
23 Alkyl halides: the character of C-X bonds, synthesis and reactions of alkyl halides; Nuclephilic substitution reactions, SN1, SN2, eliminations; Organic halides in the environment.
Dr. Kálai Tamás
24 Alkyl halides: the character of C-X bonds, synthesis and reactions of alkyl halides; Nuclephilic substitution reactions, SN1, SN2,
eliminations; Organic halides in the environment.
Dr. Kálai Tamás
25 Organometallic compounds: their importance in organic syntheses (Mg, Na, Li, Zn, Si, Cu, Cd compounds).
Dr. Kálai Tamás
26 Organometallic compounds: their importance in organic syntheses (Mg, Na, Li, Zn, Si, Cu, Cd compounds).
Dr. Kálai Tamás
27 Organometallic compounds: their importance in organic syntheses (Mg, Na, Li, Zn, Si, Cu, Cd compounds).
Dr. Kálai Tamás
28 Alcohols: Structure, synthesis, physical and chemical properties, reactions; Their biological importance.
Dr. Pápayné Dr. Sár Cecília
29 Alcohols: Structure, synthesis, physical and chemical properties, reactions; Their biological importance.
Dr. Pápayné Dr. Sár Cecília
30 Alcohols: Structure, synthesis, physical and chemical properties, reactions; Their biological importance.
Dr. Pápayné Dr. Sár Cecília
31 Phenols and ethers: Structure, synthesis, physical and chemical properties, reactions; Their biological importance: polyphenols.
Dr. Pápayné Dr. Sár Cecília
32 Phenols and ethers: Structure, synthesis, physical and chemical properties, reactions; Their biological importance: polyphenols.
Dr. Pápayné Dr. Sár Cecília
33 Phenols and ethers: Structure, synthesis, physical and chemical properties, reactions; Their biological importance: polyphenols.
Dr. Pápayné Dr. Sár Cecília
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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34 Sulfur containing compounds: Physical, chemical properties and synthesis of thiols and sulfides; Their importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs).
Dr. Pápayné Dr. Sár Cecília
35 Sulfur containing compounds: Physical, chemical properties and synthesis of thiols and sulfides; Their importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs).
Dr. Pápayné Dr. Sár Cecília
36 Sulfur containing compounds: Physical, chemical properties and synthesis of thiols and sulfides; Their importance in biological
processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs).
Dr. Pápayné Dr. Sár Cecília
37 Overview of reaction mechanisms: radical, electrophilic and nucleophilic substitutions, electrophilic additions, eliminations.
Dr. Pápayné Dr. Sár Cecília
38 Overview of reaction mechanisms: radical, electrophilic and nucleophilic substitutions, electrophilic additions, eliminations.
Dr. Pápayné Dr. Sár Cecília
39 Overview of reaction mechanisms: radical, electrophilic and nucleophilic substitutions, electrophilic additions, eliminations.
Dr. Pápayné Dr. Sár Cecília
40 Summary
Dr. Pápayné Dr. Sár Cecília
41 Summary
Dr. Pápayné Dr. Sár Cecília
42 Summary
Dr. Pápayné Dr. Sár Cecília
Practices
Seminars
Exam topics/questions
1.) Alkanes: Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, combustion, free radical chlorination, conformation, cycloalkanes, type of ring strains, demonstrate with examples.
2. Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and alkynes.
Electrophilic addition, Markovnikovs rule, 1,2- and 1,4-addition, conjugated and cumulated dienes.
3. Importance of unsaturated hydrocarbons in industry and biology; polymerization, isoprene, terpenes, steroids, carotenoids, polymers, rubber
4. Aromatic compounds: the structure of benzene, Hückels rule. Electrophilic aromatic substitution reactions. (Nitation, sulfonation,
bromination, Friedel-Crafts reactions), direction rules, classification of substituents, polyaromatics: examples, their chemical reactions aromatic electophilic substitution, oxidation.
5. Alkyl halides: the character of C-X bonds, physical properties, reactivity of alkyl halides, synthesis of alkyl and aromatic halides, and reactions of alkyl halides (substitution, elimination); Organic halides in the environment.
6. Organometallic compounds: their structure, their importance in organic syntheses (Mg, Na, Li, Si, Cu, Cd compounds).
7. Alcohols, phenols, ethers: Structure, physical and chemical properties, reactions; Their biological importance.
8. Stereochemistry: isomerism, absolute and relative configuration, chirality, racemates, diastereomers, polarimetry, resolution.
9. Sulfur containing compounds: Physical, chemical properties, importance in biological processes (in amino acids, peptides, methylation
in biology, AcCo-A, drugs, sulfonamides, penicillin, cefalosporin).
The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from failed).
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPA-V1G-T ORGANIC CHEMISTRY 1 - PRACTICE
Course director: DR. TAMÁS KÁLAI, professor
Department of Organic and Pharmacological Chemistry
3 credit ▪ midsemester grade ▪ Basic subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 42 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 2 – 80 Prerequisites: OPA-L1E-T completed + OPA-AM1-T completed
Topic
The aims of this course are to introduce students into several basic laboratory techniques and to demonstrate some characteristic reactions of organic compounds with various functional groups.
Conditions for acceptance of the semester
During the semester students have to accomplish the preparative works and written tests. They have to document the experiments in their
exercise book.
Mid-term exams
The organic chemistry laboratory course will be graded (1-5), based on the two written tests on 5th and 11th week, first of all. The
evaluation can be modified by grades of semi-micro preparations, success of unknown identification as well as the outlook of the records
of exercise book.
Making up for missed classes
Students have to contact their lab TA within 48 hours of missing lab to make the necessary arrangements.
Reading material
- Obligatory literature
- Literature developed by the Department
Kálai, T., Bognár, B. Organic Chemisry Laboratory Manual, Dept. of Org. and Med. Chem., Medical Faculty, University of Pécs, 2010.
- Notes
- Recommended literature
Charles F. Wilcox, Jr., Mary F. Wilcox: Experimental Organic Chemistry: a Small-scale Approach, 2nd ed., Prentice-Hall, London, 1995.
Dana W. Mayo, Ronald M. Pike, Peter K. Trumper: Microscale Organic Laboratory with Multistep and Multiscale Syntheses, 3rd ed., Wiley, New York, 1994.
Lectures
Practices
1 General instructions for work in the laboratory, safety precautions. Introduction to use of common laboratory apparatus.
Characteristic reactions of alkanes, alkenes and alkynes.
2 General instructions for work in the laboratory, safety precautions. Introduction to use of common laboratory apparatus. Characteristic reactions of alkanes, alkenes and alkynes.
3 General instructions for work in the laboratory, safety precautions. Introduction to use of common laboratory apparatus. Characteristic reactions of alkanes, alkenes and alkynes.
4 Basic laboratory operations I.: Synthesis of acetanilide (heating, cooling, stirring, filtration with vacuum, crystallisation).
5 Basic laboratory operations I.: Synthesis of acetanilide (heating, cooling, stirring, filtration with vacuum, crystallisation).
6 Basic laboratory operations I.: Synthesis of acetanilide (heating, cooling, stirring, filtration with vacuum, crystallisation).
7 Basic laboratory operations II: Determination of the melting point, separation of dies with column chromatography; Characteristic tube reactions of alkanes, aromatic hydrocarbons and alkenes.
8 Basic laboratory operations II: Determination of the melting point, separation of dies with column chromatography; Characteristic tube reactions of alkanes, aromatic hydrocarbons and alkenes.
9 Basic laboratory operations II: Determination of the melting point, separation of dies with column chromatography; Characteristic tube reactions of alkanes, aromatic hydrocarbons and alkenes.
10 Basic laboratory operations III: Synthesis of tert-butyl-chloride (extraction, drying, filtration, distillation, determination of the boiling point); Identification of 1st unknown compound.
11 Basic laboratory operations III: Synthesis of tert-butyl-chloride (extraction, drying, filtration, distillation, determination of the
boiling point); Identification of 1st unknown compound.
12 Basic laboratory operations III: Synthesis of tert-butyl-chloride (extraction, drying, filtration, distillation, determination of the boiling point); Identification of 1st unknown compound.
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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13 Synthesis of p-bromo-acetanilide and p-nitro-acetanilide. Characteristic tube reactions of alkyl halides.
14 Synthesis of p-bromo-acetanilide and p-nitro-acetanilide. Characteristic tube reactions of alkyl halides.
15 Synthesis of p-bromo-acetanilide and p-nitro-acetanilide. Characteristic tube reactions of alkyl halides.
16 1st written test; Characteristic tube reactions of alcohols, phenols and ethers.
17 1st written test; Characteristic tube reactions of alcohols, phenols and ethers.
18 1st written test; Characteristic tube reactions of alcohols, phenols and ethers.
19 Synthesis of fluorenol with reduction and fluorenone with oxidation; Identification of 2nd unknown compound;
20 Synthesis of fluorenol with reduction and fluorenone with oxidation; Identification of 2nd unknown compound;
21 Synthesis of fluorenol with reduction and fluorenone with oxidation; Identification of 2nd unknown compound;
22 Basic laboratory operations IV: thin layer chromatography, introduction to infrared spectroscopy. Isolation of piperine.
23 Basic laboratory operations IV: thin layer chromatography, introduction to infrared spectroscopy. Isolation of piperine.
24 Basic laboratory operations IV: thin layer chromatography, introduction to infrared spectroscopy. Isolation of piperine.
25 Preparation of 4-amino-benzenesulfonamide and nitrobenzene.
26 Preparation of 4-amino-benzenesulfonamide and nitrobenzene.
27 Preparation of 4-amino-benzenesulfonamide and nitrobenzene.
28 Preparation of 4-amino-benzenesulfonamide and nitrobenzene.
29 Preparation of 4-amino-benzenesulfonamide and nitrobenzene.
30 Preparation of 4-amino-benzenesulfonamide and nitrobenzene.
31 2nd written test. Characteristic reactions of amines.
32 2nd written test. Characteristic reactions of amines.
33 2nd written test. Characteristic reactions of amines.
34 Preparation of anthranilic acid; Identification of 3rd unknown compound.
35 Preparation of anthranilic acid; Identification of 3rd unknown compound.
36 Preparation of anthranilic acid; Identification of 3rd unknown compound.
37 Preparation of 2-iodobenzoic acid;
38 Preparation of 2-iodobenzoic acid;
39 Preparation of 2-iodobenzoic acid;
40 Evaluation.
41 Evaluation.
42 Evaluation.
Seminars
Exam topics/questions
The written tests will contain the matter of practice.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Bognár Balázs (BOBGAAT.PTE), Dr. Kálai Tamás (KATFABP.PTE), Dr. Pápayné Dr. Sár Cecília (PASFADP.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPO-AI2-T HUMAN ANATOMY, HISTOLOGY AND EMBRIOLOGY 2
Course director: DR. GABRIELLA HORVÁTH-OPPER, assistant professor
Department of Anatomy
2 credit ▪ semester exam ▪ Med.-biol. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 14 lectures + 0 practices + 14 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – 100 Prerequisites: OPO-AI1-T completed
Topic
The subject describes the macroscopic and microscopic structure of the human body. Students will learn in lectures (1x45 min/week)
and seminars (1x90 min. every even week) how the organs are built up. In the second part of the 2-Semester study macroscopic and
microscopic anatomy of the reproductive system, endocrine organs and the nervous system are represented with the aid of formalin-fixed cadavers, organ preparations and plastic models. General embryology includes the most important steps of the human development.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
-
Making up for missed classes
The seminars can be made up with the attendance in the seminar of another pharmacy group of the same week (only twice in a semester
possible)
Reading material
- Obligatory literature
http://an-server.pote.hu
- Literature developed by the Department
http://an-server.pote.hu
- Notes
http://an-server.pote.hu
- Recommended literature
http://an-server.pote.hu
Lectures
1 Male genital organs
Dr. Kiss Péter
2 Female genital organs 1. Ovarium, tuba uterina, uterus. The ovulation and the menstruation cyclus.
Dr. Tamás Andrea
3 Female genital organs 2. Pregnancy, placenta. Vagina, external genital organs.
Dr. Tamás Andrea
4 The main parts of the human development. Main steps during the zygote and the embryonic period.
Dr. Kiss Péter
5 Parts of the nervous system. Peripheral nervous system.
Dr. Tóth Pál
6 Macroscopic structure of the central nervous system. (Main parts, ventricles, meninges, blood supply)
Dr. Tóth Pál
7 Nervous tissue
Dr. Tóth Pál
8 Sensory pathways
Dr. Gaszner Balázs
9 Motor pathways
Dr. Gaszner Balázs
10 The endocrine glands
Opper Balázs
11 The autonomic nervous system
Dr. Nagy András Dávid
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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12 Structure of the visual system
Dr. Horváth-Opper Gabriella
13 Structure of the auditory and the vestibular system
Dr. Horváth-Opper Gabriella
14 Fetal period. Signs of the maturity od the newborn baby. Malformations and their causes.
Dr. Farkas Boglárka Anett
Practices
Seminars
1 Anatomy: organs of the lesser pelvis
2 Anatomy: organs of the lesser pelvis
3 Histology: ovary, uterus, vagina, testis, prostate gland
4 Histology: ovary, uterus, vagina, testis, prostate gland
5 Anatomy: spinal cord, meninges, cranial nerves
6 Anatomy: spinal cord, meninges, cranial nerves
7 Anatomy: macroscopic structure of the brain
8 Anatomy: macroscopic structure of the brain
9 Histology: peripheral nerve, spinal cord, cerebellum, neocortex
10 Histology: peripheral nerve, spinal cord, cerebellum, neocortex
11 Histology: pituitary gland, thyroid gland, suprarenal gland
12 Histology: pituitary gland, thyroid gland, suprarenal gland
13 Anatomy: eye, inner and middle ear with models
14 Anatomy: eye, inner and middle ear with models
Exam topics/questions
Written test (A chance) at the beginning of the exam period. B, C and D chances are oral exams.
http://an-server.pote.hu
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Jüngling Adél (JUARAAO.PTE), Dr. Kovács László Ákos (KOLQAAO.PTE), Dr. Kovács László Ákos (KOLQAAO.PTE), Gaszner Tamás (GATRAAO.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
14
OPO-G1E-T PHARMACOBOTANY 1 - THEORY
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy
1 credit ▪ semester exam ▪ Med.-biol. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 3 – 100 Prerequisites: OPO-G1G-T parallel
Topic
Pharmacobotany covers all pharmaceutical aspects of botany, including cytology, histology, morphology and taxonomy of plants. Plant
systematics discusses the geographical origin of plant species, the possibilities of their cultivation and protection. A special emphasis is
laid on chemotaxonomic aspects, since the medicinal effect of a plant is often related to its taxonomic classification and chemical
characteristics. Practical instruction focuses on the knowledge of medicinal plants, including the confident use of plant identification
keys. Based on their knowledge of histology and morphology, students are required to apply proper anatomical terms, and finally identify
plant species (taxa). The thorough knowledge of both general and specific pharmacobotany is a prerequisite of studying pharmacognosy.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Students have to pass (min. 60%)two written exams based on lecture materials. The exams will be held on the 7th and 13th week of the
semester.
For each test, maximum two other chances (B and C chance) will be offered for students who do not pass the exam on the first occassion
(A chance).
Making up for missed classes
Lecture materials can be downloaded from the website of the Department of Pharmacognosy (Educational Materials).
Reading material
- Obligatory literature
Á. Farkas: Pharmacobotany 1, University of Pécs, Institute of Pharmacognosy, Pécs, 2010
- Literature developed by the Department
Farkas Á., Papp N., Bencsik T., Horváth Gy.: Digital Herbarium and Drug Atlas, electronic learning material, 2014 TÁMOP-4.1.2.A/1-11/1-2011-0016
- Notes
- Recommended literature
D.F. Cutler, T. Botha, D.W. Stevenson: Plant Anatomy. An Applied Approach, Wiley-Blackwell, 2008
R.F. Evert, S.E. Eichhorn: Esaus Plant Anatomy: Meristems, Cells and Tissues of the Plant Body: Their Structure, Function and
Development, 3rd edition, Wiley
A. Fahn: Plant Anatomy, 4th edition
Lectures
1 Structure of the plant cell. Plastids and inclusions.
Dr. Farkas Ágnes
2 Structure of the cell wall.
Dr. Farkas Ágnes
3 Plant tissues I. Meristematic tissues.
Dr. Farkas Ágnes
4 Plant tissues II. Epidermal tissue; stomata, trichomes, secondary epidermis.
Dr. Farkas Ágnes
5 Plant tissues III. Vascular tissues; vascular bundle types.
Dr. Farkas Ágnes
6 Plant tissues IV. Ground tissues: parenchyma, collenchyma, sclerenchyma, secretory tissues.
Dr. Farkas Ágnes
7 1st written exam
Dr. Farkas Ágnes
8 Root morphology. Modified roots. Root anatomy
Dr. Farkas Ágnes
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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9 Shoot morphology and anatomy. Shoot types.
Dr. Farkas Ágnes
10 Leaf morphology and anatomy. Leaf arrangement (phyllotaxis). Leaf venation.
Dr. Farkas Ágnes
11 Flower morphology. Inflorescence types.
Dr. Farkas Ágnes
12 Fertilisation, embryogenesis, ovule and seed. Fruit types.
Dr. Farkas Ágnes
13 2nd written exam
Dr. Farkas Ágnes
14 Taxonomic categories, chemotaxonomic relations, rules of nomenclature.
Dr. Farkas Ágnes
Practices
Seminars
Exam topics/questions
The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from failed).
The grades of the 2 written lecture tests serve as the basis of the final course grade.
Exam topics:
1. Structure of the plant cell.
2. Plastids and inclusions.
3. Structure of the cell wall.
4. Meristematic tissues.
5. Epidermal tissue; stomata.
6. Trichomes, secondary epidermis.
7. Vascular tissues
8. Vascular bundle types.
9. Ground tissues: parenchyma, collenchyma.
10. Ground tissues: sclerenchyma, secretory tissues.
11. Root morphology and anatomy
12. Modified roots.
13. Shoot morphology and anatomy.
14. Shoot types.
15. Leaf morphology and anatomy.
16. Leaf arrangement (phyllotaxis). Leaf venation.
17. Flower morphology.
18. Inflorescence types.
19. Fertilisation, embryogenesis, ovule and seed.
20. Fruit types: dehiscent fruits.
21. Fruit types: indehiscent fruits.
22. Fruit types: compound and aggregate fruits.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
16
OPO-G1G-T PHARMACOBOTANY 1 - PRACTICE
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy
1 credit ▪ midsemester grade ▪ Med.-biol. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 14 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 3 – 100 Prerequisites: none
Topic
Pharmacobotany covers all pharmaceutical aspects of botany, including cytology, histology, morphology and taxonomy of plants. Plant
systematics discusses the geographical origin of plant species, the possibilities of their cultivation and protection. A special emphasis is
laid on chemotaxonomic aspects, since the medicinal effect of a plant is often related to its taxonomic classification and chemical
characteristics. Practical instruction focuses on the knowledge of medicinal plants, including the confident use of plant identification
keys. Based on their knowledge of histology and morphology students are required to apply proper anatomical terms, and finally identify
plant species (taxa). The thorough knowledge of both general and specific pharmacobotany is a prerequisite of studying pharmacognosy.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Students have to pass (min. 60%)two written exams based on the practice materials. The exams will be held on the 7th and 13th week of
the semester. For each test, maximum two other chances (B and C chance) will be offered for students who do not pass the exam on the
first occassion (A chance).
In the practice, students have to take notes and prepare drawings based on microscopic examinations. Students have to show their lab
notebook to the practice leader, who acknowledges fulfillment of the practice by his/her signature.
The grades of the 2 written practical tests and the lab notebook serve as the basis of the practical grade.
Making up for missed classes
Participation is compulsory in lab practices; up to 2 absences are allowed. Missed practices can be made up either by joining the other
groups or taking extra time at the following lab practice. In all cases, students must make arrangements with their lab instructors in
advance.
Reading material
- Obligatory literature
N. Papp: Pharmacobotany Practices, University of Pécs, Institute of Pharmacognosy, Pécs, 2011
- Literature developed by the Department
Farkas Á., Papp N., Bencsik T., Horváth Gy.: Digital Herbarium and Drug Atlas, electronic learning material, 2014 TÁMOP-4.1.2.A/1-11/1-2011-0016
- Notes
Á. Farkas: Pharmacobotany 1, University of Pécs, Institute of Pharmacognosy, Pécs, 2010
- Recommended literature
D.F. Cutler, T. Botha, D.W. Stevenson: Plant Anatomy. An Applied Approach, Wiley-Blackwell, 2008
Lectures
Practices
1 Use of the light microscope. Microscopic techniques and preparations (leaf clearing, cross sections, epidermal tissues). Plastids and inclusions of the plant cell. Microscopic examination of cleared leaves and starch grains.
2 Chemical substances (cellulose, lignin) and thickening types of the cell wall. Investigation of vacuolar content (inulin, alkaloids, tannins, anthocyanins). Microscopic examination of calcium oxalate and calcium carbonate crystals.
3 The root and shoot tip; meristematic tissues. Microscopic examination of cambium types.
4 Examination of the leaf epidermis and its appendages with light microscope (cross sections, epidermal casts, cleared preparations) and stereo microscope .
5 Microscopic study of the vascular tissue system and mechanical tissues in stem cross sections.
6 Microscopic examination of ground tissues. Plant secretory systems (schizogenous, lysigenous cavities, laticifers, glandular trichomes, glandular scales, nectaries). Study of aerenchyma and nutrient storing gorund tissue.
7 Identification of various plant tissues in microscope slides.
8 Morphological analysis of the root and its modifications. Microscopic examination of the tissue structure of true and modified roots.
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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9 Shoot system types, shoot modifications. Microscopic examination of the tissue structure of above ground and below ground shoot types.
10 Leaf types, leaf arrangement, parts of the leaf. Shape, margin and venation of leaves, leaf modifications. Microscopic analysis of
leaf cross sections.
11 Morphological analysis of the flower: perianth, androecium, gynoecium. Floral formula, floral diagram. Microscopic study of
flower parts.
12 Morphological investigation of inflorescences. Identification of inflorescence type on herbarium specimens. Microscopic examination of capitulum.
13 Fruit morphology: Dry dehiscent and indehiscent fruits.
14 Fruit morphology: Fleshy fruits, compound fruits and false fruits.
Seminars
Exam topics/questions
1. Structure of the plant cell.
2. Plastids and inclusions.
3. Structure of the cell wall.
4. Meristematic tissues.
5. Epidermal tissue; stomata.
6. Trichomes, secondary epidermis.
7. Vascular tissues
8. Vascular bundle types.
9. Ground tissues: parenchyma, collenchyma.
10. Ground tissues: sclerenchyma, secretory tissues.
11. Root morphology and anatomy
12. Modified roots.
13. Shoot morphology and anatomy.
14. Shoot types.
15. Leaf morphology and anatomy.
16. Leaf arrangement (phyllotaxis). Leaf venation.
17. Flower morphology.
18. Inflorescence types.
19. Fertilisation, embryogenesis, ovule and seed.
20. Fruit types: dehiscent fruits.
21. Fruit types: indehiscent fruits.
22. Fruit types: compound and aggregate fruits.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Farkas Ágnes (FAADAB.T.JPTE), Dr. Papp Nóra (PANAAA.T.JPTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
18
OPO-H1E-T HUMAN PHYSIOLOGY 1 - THEORY
Course director: DR. ZOLTÁN KARÁDI, professor
Institute of Physiology
3 credit ▪ semester exam ▪ Med.-biol. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 42 lectures + 0 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 5 – not limited Prerequisites: OPO-GB2-T completed + OPO-AI2-T parallel + OPO-H1G-T parallel
Topic
The most important mission of the Physiology Course in medical education is to familiarize students with the attributes of healthy
functions of the living organism.
While acquiring knowledge about the most important functional characteristics of the human body the students can rely on their prior
studies in biology, biophysics, chemistry-biochemistry and anatomy.
During the semester we introduce the most important elements of functioning of the organs and organ systems, as well as their cooperation also required to adapting to the environment, and the factors affecting these processes.
Special emphasis is placed on the neural and humoral regulatory processes of these life-functions, which are vital to maintain and preserve the homeostasis of the organism.
With the transfer of all this knowledge we would like to mould a holistic attitude and thinking of students, which will enable them to better understand the functions of the now healthy, however, later dysfunctional human organism.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written test on the 11th week Friday at 16:00.
Making up for missed classes
The missed lab practice is advised to be covered by joining another group while the same topic is on schedule.
Reading material
- Obligatory literature
J.E. Hall: Guyton and Hall Textbook of Medical Physiology, 12th edition, 2013
- Literature developed by the Department
Figures of the lectures given are available on the homepage of Institute of Physiology and on the Neptun Meet Street.
Important messages on new information will be announced at the lectures and will be sent to you by course mails.
Please always find the current updated information and study materials on the homepage of the Institute of Physiology (physiology.aok.pte.hu).
- Notes
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practices 1, internet study material, printable notebook, 2014
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practice Worksheets 1, internet study material, printable notebook, 2014
- Recommended literature
L.S. Costanzo: Physiology, 5th edition, 2014
W.F. Ganong: Review of Medical Physiology, 2012, Appleton and Lange, Lange Medical Publications
Fonyó: Principles of Medical Physiology, Medicina Publishing, 2002
J.B. West (ed.): Best and Taylor’s Physiological Basis of Medical Practice, Williams and Wilkins, 1998
Lectures
1 Introduction. Principles of the homeostatic regulations.
Dr. László Kristóf
2 Cellular transport processes. Humoral control mechanisms.
Dr. Környei József László
3 Basics of electrophysiology. Equilibrium potential, electrotonic potentials and action potential.
Dr. Buzás Péter
4 Basics of autonomic nervous system and muscle functions.
Dr. Buzás Péter
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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5 Fluid distribution in the body. The blood.
Dr. Zelena Dóra
6 Anorganic and organic blood constituents. The physiological role of leukocytes.
Kertes Erika
7 Structure and metabolism of hemoglobin.
Metabolism of iron.
Dr. Szabó István
8 Mechanism of blood coagulation.
Dr. Szabó István
9 Blood group systems.
Dr. Szabó István
10 The cardiac cycle.
Generators and conductors of impulses in the heart.
Dr. Környei József László
11 Electrocardiogram.
Dr. Gálosi Rita
12 Distribution of blood volume, pressure flow and resistance in the heart. Heart sounds.
Dr. Környei József László
13 Cardiac output and cardiac work.
Dr. Környei József László
14 Distribution of blood volume, pressure flow and resistance. Blood pressure. Arterial pulse
Dr. Ábrahám István Miklós
15 Circulation through the capillaries. Circulation in the veins. The formation, pressure and flow of lymph.
Kóbor Péter
16 Pulmonary circulation, cerebral circulation. Circulation of the skin and skeletal muscle. Splanchnic circulation. Coronary circulation.
Kóbor Péter
17 Neural and humoral regulatory mechanisms of the cardiovascular system.
Homeostatic regulation of the cardiovascular system.
Dr. László Kristóf
18 Mechanics of respiration Intrathoracic pressure. Compliance. Respiratory volumes. Dead spaces.
Dr. Környei József László
19 Gaseous exchange in the lungs and tissues. Chemical control of respiration. O2 and CO2 transport mechanism and pH regulation.
Dr. Környei József László
20 Neural regulatory mechanisms of respiration. Mechanisms of acclimatization.
Petykó Zoltán
21 The gastrointestinal tract. Function and control of salivary secretion. The stomach. Gastric secretion.
Dr. Buzásné Dr. Telkes Ildikó
22 Duodenal processes. Biliary secretion. Secretion and absorption in the small intestine.
Dr. Buzásné Dr. Telkes Ildikó
23 Liver functions.
Péczely László Zoltán
24 Secretion and absorption in the large intestine. Formation of the feces. Digestion and absorption of different nutrients. Vitamins.
Dr. Ollmann Tamás
25 Humoral and neural control of the gastrointestinal system.
Dr. Buzásné Dr. Telkes Ildikó
26 Dynamics of glomerular filtration. Plasma clearance. Renal blood flow. Extraction ratio. Filtration fraction.
Dr. László Kristóf
27 Renal circulation. The renin-angiotensin system.
Dr. László Kristóf
28 Tubular processes. Concentrating and diluting mechanisms. Osmoregulation.
Dr. László Kristóf
29 Fluid volume regulation of the body. The mechanisms of urination.
Dr. László Kristóf
30 Acid-base regulation.
Dr. Jandó Gábor
31 Energy balance. Metabolism. Nutrition. Body mass regulation.
Dr. Környei József László
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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32 Body temperature of man. Hyperthermia, fever.
Kertes Erika
33 Peripheral control of body temperature.
Central control mechanisms of body temperature.
Kertes Erika
34 The hypothalamo-hypophyseal system.
Dr. Ábrahám István Miklós
35 Anterior pituitary hormones.
Dr. Ábrahám István Miklós
36 Cellular mechanisms of hormone action.
Dr. Ábrahám István Miklós
37 Hormonal regulation of female sexual functions.
Dr. Lengyel Ferenc
38 Pregnancy. Parturition and lactation.
Dr. Ráczné Dr. Mikó-Baráth Eszter
39 Hormonal regulation of male sexual function.
Erection, ejaculation, coitus. Humoral and central neural control of sexual behavior.
Kóbor Péter
40 Puberty. Climacteric.
Kóbor Péter
41 Functions of posterior lobe of pituitary gland.
Péczely László Zoltán
42 Thyroid physiology.
Kovács Anita
Practices
Seminars
Exam topics/questions
The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from ?failed?).
Topics of questions for the theoretical examination
1. Describe the body fluid compartments and explain the methods used for measurement of body fluid volumes
2. Describe the major plasma proteins and the other non-electrolytic constituents of blood and explain their function in the body
3. Describe the intra- and extracellular ionic components and explain their physiological functions
4. The structure, function and origin of erythrocytes
5. Characterize the various leukocytes indicating their origins and functions
6. Origin and function of blood platelets
7. The basic structure and metabolism of haemoglobin and the metabolism of iron
8. Describe the two pathways involved in the initiation of blood coagulation
9. Specific mechanism of clot formation
10. Describe the mechanism of fibrinolysis. Explain the significance of anticlotting mechanism
11. Regulation of H+ ion concentration in the blood
12. A-B-0 blood groups. The Rh blood types
13. The role of leukocytes in the defence mechanism
14. Mechanical activity of the heart and the three-component model of heart muscle. Calcium ion movements within the cardiac muscle cell
15. Generators and conductors of impulses in the heart. Refractory periods
16. The sequence of events in the cardiac cycle
17. The human electrocardiogram (ECG). Electrocardiography: bipolar and unipolar leads
18. The heart sounds. Phonocardiography (PCG)
19. Cardiac output: measurement, normal standards and physiological variations
20. Metabolism and energetics of cardiac muscle
21. Ventricular wall tension and the Laplace relationship
22. The heart-lung preparation (Starling`s laws)
23. Arterial blood pressure: determinants of normal arterial blood pressure
24. The arterial and the venous pulse. Basic principles of hemodynamics.
25. Circulation through the capillaries
26. The properties, production and the movement of lymph
27. Circulation in the vein. Effect of gravity on circulation
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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28. The pulmonary circulation. Control of lung vessels
29. The coronary circulation
30. Cerebral circulation. The concept of blood-brain barrier.
31. Splanchnic circulation
32. Skeletal muscle circulation. Cutaneous circulation
33. Nervous control of the heart
34. Control mechanisms of the circulatory system: general considerations
35. Local control of the vascular smooth muscle
36. Autoregulation of blood flow in tissues and organs
37. The function and importance of baroreceptors in the regulation of circulation
38. Reflex control mechanisms of circulation
39. Mechanisms of vasoconstriction and vasodilatation
40. Mechanics of respiration (functions of respiratory muscles, compliance, intrathoracic pressures, respiratory volumes)
41. Alveolar air, alveolar ventilation, dead spaces. Function of the respiratory passageways
42. Gaseous exchange in the lungs and tissues
43. O2 and CO2 transport in the body
44. Peripheral and central regulatory mechanisms of respiration. Respiratory reflexes
45. Chemical control of respiration. Acidosis, alkalosis
46. Different types of hypoxia. Oxygen treatment. Mechanisms of acclimatisation. Nitrogen narcosis. Decompression sickness
47. Describe the origin, composition, function and control of salivary secretion
48. Describe the origin, nature and function of gastric secretion indicating the mechanisms of regulation
49. Mechanism and regulation of gastrointestinal movements
50. Identify the pancreatic secretions, their components, their action and the substrates on which they act. Control mechanism of pancreatic secretion
51. Describe the basic ingredients and functions of the bile indicating the origin and fate of the components and the factors controlling
bile secretions and gall bladder functions
52. Identify the components and functions of the intestinal system
53. Describe how carbohydrate is digested and absorbed indicating the enzymes involved
54. Describe how fat is digested and absorbed indicating the enzymes and secretions involved
55. Describe how protein is digested and absorbed indicating the enzymes and secretions involved
56. Dynamics of glomerular filtration. Glomerular filtration rate. Plasma clearance
57. Renal blood flow. Clearance of PAH. Extraction ratio. Filtration fraction
58. Regulation of renal blood flow and pressure. Renin-angiotensin system
59. Reabsorption and secretion of different substances in the renal tubule. Methods for their investigation
60. Concentrating and diluting mechanisms of the kidney
61. Fluid volume regulation of the body
62. Regulation of concentrations of ions in the extracellular fluid. Regulation of osmolality of body fluids
63. Basal metabolic rate. Describe factors influencing the basal metabolism
64. Define metabolic rate explaining those factors influencing the total expenditure of energy by the body
65. Describe the necessary elements of normal diet
66. The normal body temperature and its physiological variations. Hyperthermia, fever, hypothermia
67. Chemical regulation of body temperature, changes of regulation at low and high environmental temperature
68. Physical regulation of body temperature, changes of regulation at low and high environmental temperature
69. Central regulatory mechanisms of heat production and heat loss
70. Mechanisms of hormone action (receptors, intracellular mediators, cAMP, Ca2+ and diacylglycerol, protein kinases)
71. Mechanism of hormonal regulation. Negative and positive feedback controls in the endocrine system
72. The anterior pituitary hormones. Regulation of pituitary hormone secretions. Pituitary dysfunction
73. Function of growth hormone during development and after adolescence
74. Abnormalities of thyroid secretion. Goitrogens
75. Function of the thyroid gland. Iodine metabolism in the body
76. Hormonal changes during menstrual cycle
77. Hormonal changes during pregnancy. Role of placenta in pregnancy. Foeto-placental unit
78. Hormones of lactation
79. Mechanism of erection and ejaculation. The sexual act (coitus)
80. The function of testis, epididymis, seminal vesicle and prostate
81. Regulation of the sexual behaviour. Maternal behaviour
82. Physiological changes at puberty and climacteric
83. Vasopressin and oxytocin. Function of ANH (atrionatriuretic hormone)
84. The effects of prostaglandins
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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Questions for the student lab report:
1. Hematocrit
2. Red blood cell counting
3. White blood cell counting
4. Differential leukocyte count
5. Determination of osmotic resistance.
6. Determination of hemoglobin concentration
7. MCV, MCH, MCHC values
8. Prothrombin time
9. Blood group determination (AB0 and Rh typing)
10. Examination of hemoglobin spectra
11. How to use work stations for electrophysiological registrations
12. Recording of heart beats of the frog „in situ”
13. Electric stimulation of heart (demonstr. of extrasystole)
14. Effect of thermal stimulations of frog’s heart.
15. Ligatures of Stannius
16. Investigation of Bowditch’s „All or nothing” law
17. Investigation of summation
18. Electrocardiography (ECG)
19. Examination of the arterial pulse
20. Measurement of blood pressure in human
21. Isolated frog’s heart preparing by Straub cannulla
22. Effect of acethylcholin on isolated frog’s heart
23. Effect of adrenalin on isolated frog’s heart
24. Effect of ions on the isolated heart
25. Direct measurement of blood pressure in cat
26. The circulation through capillaries of frog’s tongue.
27. Pulse wave registration.
28. Spirometry, dynamic parameters of respiration
29. Volumes and capacities of the lungs.
30. Measurement of maximal respiratory pressures (The experiments of Müller and Valsalva)
31. Demonstration of basic respiratory movements and pressure/volume changes (Donders model)
32. Gastric juice: Determination of BAO, MAO, PAO
33. Bile: detection of bile pigments
34. Feces: Detection of blood (Guajac-, benzidin-, Hematest)
35. Measurement of the actual metabolic rate in human
36. Measurement of the oxigen consumption in rat.
37. Specific gravity of urine.
38. Examination of the urine sediment
39. Urine examination with reagent strip methodology
40. Examination of pathological urine components with tests in tubes: protein, glucose, keton bodies, blood, ubg, bilirubin, pus detections
Study material for the semester exam is the sum total of information covered in the obligatory textbook, on the homepage of the Institute, as well as knowledge given at the lectures and lab practices.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
23
OPO-H1G-T HUMAN PHYSIOLOGY 1 - PRACTICE
Course director: DR. ZOLTÁN KARÁDI, professor
Institute of Physiology
2 credit ▪ midsemester grade ▪ Med.-biol. theoretical module and practical skills subject ▪ autumn semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – not limited Prerequisites: OPO-GB2-T completed + OPO-AI2-T parallel
Topic
The most important mission of the Physiology Course in medical education is to familiarize students with the attributes of healthy functions of the living organism.
While acquiring knowledge about the most important functional characteristics of the human body the students can rely on their prior
studies in biology, biophysics, chemistry-biochemistry and anatomy.
During the semester we introduce the most important elements of functioning of the organs and organ systems, as well as their cooperation also required to adapting to the environment, and the factors affecting these processes.
Special emphasis is placed on the neural and humoral regulatory processes of these life-functions, which are vital to maintain and preserve the homeostasis of the organism.
With the transfer of all this knowledge we would like to mould a holistic attitude and thinking of students, which will enable them to better understand the functions of the now healthy, however, later dysfunctional human organism.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written test on the 11th week Friday at 16:00.
Making up for missed classes
The missed lab practice is advised to be covered by joining another group while the same topic is on schedule.
Reading material
- Obligatory literature
J.E. Hall: Guyton and Hall Textbook of Medical Physiology, 12th edition, 2013
- Literature developed by the Department
Figures of the lectures given are available on the homepage of Institute of Physiology and on the Neptun Meet Street.
Important messages on new information will be announced at the lectures and will be sent to you by course mails.
Please always find the current updated information and study materials on the homepage of the Institute of Physiology (physiology.aok.pte.hu).
- Notes
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practices 1, internet study material, printable notebook, 2014
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practice Worksheets 1, internet study material, printable notebook,
2014
- Recommended literature
L.S. Costanzo: Physiology, 5th edition, 2014
W.F. Ganong: Review of Medical Physiology, 2012, Appleton and Lange, Lange Medical Publications
Fonyó: Principles of Medical Physiology, Medicina Publishing, 2002
J.B. West (ed.): Best and Taylor’s Physiological Basis of Medical Practice, Williams and Wilkins, 1998
Lectures
Practices
1 Getting acquainted with the laboratory. General information, schedules. Personal- and equipment safety rules. Animal care regulations.
2 Getting acquainted with the laboratory. General information, schedules. Personal- and equipment safety rules. Animal care
regulations.
3 Blood I.
4 Blood I.
5 Blood II.
6 Blood II.
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7 Blood III.
8 Blood III.
9 Seminar: Blood (Discussion of the topics covered by the lectures and student labs)
10 Test on the chapter
11 The heart and circulation I.
12 The heart and circulation I.
13 The heart and circulation II.
14 The heart and circulation II.
15 The heart and circulation III.
16 The heart and circulation III.
17 The heart and circulation IV.
18 The heart and circulation IV.
19 Seminar: The heart and circulation
20 Test on the chapter
21 Respiration
22 Respiration
23 Gastrointestinal tract
24 Gastrointestinal tract
25 Examination of the urine
26 Examination of the urine
27 Measurement of the actual metabolic rate in human
28 Measurement of the actual metabolic rate in human
Seminars
Exam topics/questions
Topics of questions for the theoretical examination
1. Describe the body fluid compartments and explain the methods used for measurement of body fluid volumes
2. Describe the major plasma proteins and the other non-electrolytic constituents of blood and explain their function in the body
3. Describe the intra- and extracellular ionic components and explain their physiological functions
4. The structure, function and origin of erythrocytes
5. Characterize the various leukocytes indicating their origins and functions
6. Origin and function of blood platelets
7. The basic structure and metabolism of haemoglobin and the metabolism of iron
8. Describe the two pathways involved in the initiation of blood coagulation
9. Specific mechanism of clot formation
10. Describe the mechanism of fibrinolysis. Explain the significance of anticlotting mechanism
11. Regulation of H+ ion concentration in the blood
12. A-B-0 blood groups. The Rh blood types
13. The role of leukocytes in the defence mechanism
14. Mechanical activity of the heart and the three-component model of heart muscle. Calcium ion movements within the cardiac muscle cell
15. Generators and conductors of impulses in the heart. Refractory periods
16. The sequence of events in the cardiac cycle
17. The human electrocardiogram (ECG). Electrocardiography: bipolar and unipolar leads
18. The heart sounds. Phonocardiography (PCG)
19. Cardiac output: measurement, normal standards and physiological variations
20. Metabolism and energetics of cardiac muscle
21. Ventricular wall tension and the Laplace relationship
22. The heart-lung preparation (Starling`s laws)
23. Arterial blood pressure: determinants of normal arterial blood pressure
24. The arterial and the venous pulse. Basic principles of hemodynamics.
25. Circulation through the capillaries
26. The properties, production and the movement of lymph
27. Circulation in the vein. Effect of gravity on circulation
28. The pulmonary circulation. Control of lung vessels
29. The coronary circulation
30. Cerebral circulation. The concept of blood-brain barrier.
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31. Splanchnic circulation
32. Skeletal muscle circulation. Cutaneous circulation
33. Nervous control of the heart
34. Control mechanisms of the circulatory system: general considerations
35. Local control of the vascular smooth muscle
36. Autoregulation of blood flow in tissues and organs
37. The function and importance of baroreceptors in the regulation of circulation
38. Reflex control mechanisms of circulation
39. Mechanisms of vasoconstriction and vasodilatation
40. Mechanics of respiration (functions of respiratory muscles, compliance, intrathoracic pressures, respiratory volumes)
41. Alveolar air, alveolar ventilation, dead spaces. Function of the respiratory passageways
42. Gaseous exchange in the lungs and tissues
43. O2 and CO2 transport in the body
44. Peripheral and central regulatory mechanisms of respiration. Respiratory reflexes
45. Chemical control of respiration. Acidosis, alkalosis
46. Different types of hypoxia. Oxygen treatment. Mechanisms of acclimatisation. Nitrogen narcosis. Decompression sickness
47. Describe the origin, composition, function and control of salivary secretion
48. Describe the origin, nature and function of gastric secretion indicating the mechanisms of regulation
49. Mechanism and regulation of gastrointestinal movements
50. Identify the pancreatic secretions, their components, their action and the substrates on which they act. Control mechanism of
pancreatic secretion
51. Describe the basic ingredients and functions of the bile indicating the origin and fate of the components and the factors controlling bile secretions and gall bladder functions
52. Identify the components and functions of the intestinal system
53. Describe how carbohydrate is digested and absorbed indicating the enzymes involved
54. Describe how fat is digested and absorbed indicating the enzymes and secretions involved
55. Describe how protein is digested and absorbed indicating the enzymes and secretions involved
56. Dynamics of glomerular filtration. Glomerular filtration rate. Plasma clearance
57. Renal blood flow. Clearance of PAH. Extraction ratio. Filtration fraction
58. Regulation of renal blood flow and pressure. Renin-angiotensin system
59. Reabsorption and secretion of different substances in the renal tubule. Methods for their investigation
60. Concentrating and diluting mechanisms of the kidney
61. Fluid volume regulation of the body
62. Regulation of concentrations of ions in the extracellular fluid. Regulation of osmolality of body fluids
63. Basal metabolic rate. Describe factors influencing the basal metabolism
64. Define metabolic rate explaining those factors influencing the total expenditure of energy by the body
65. Describe the necessary elements of normal diet
66. The normal body temperature and its physiological variations. Hyperthermia, fever, hypothermia
67. Chemical regulation of body temperature, changes of regulation at low and high environmental temperature
68. Physical regulation of body temperature, changes of regulation at low and high environmental temperature
69. Central regulatory mechanisms of heat production and heat loss
70. Mechanisms of hormone action (receptors, intracellular mediators, cAMP, Ca2+ and diacylglycerol, protein kinases)
71. Mechanism of hormonal regulation. Negative and positive feedback controls in the endocrine system
72. The anterior pituitary hormones. Regulation of pituitary hormone secretions. Pituitary dysfunction
73. Function of growth hormone during development and after adolescence
74. Abnormalities of thyroid secretion. Goitrogens
75. Function of the thyroid gland. Iodine metabolism in the body
76. Hormonal changes during menstrual cycle
77. Hormonal changes during pregnancy. Role of placenta in pregnancy. Foeto-placental unit
78. Hormones of lactation
79. Mechanism of erection and ejaculation. The sexual act (coitus)
80. The function of testis, epididymis, seminal vesicle and prostate
81. Regulation of the sexual behaviour. Maternal behaviour
82. Physiological changes at puberty and climacteric
83. Vasopressin and oxytocin. Function of ANH (atrionatriuretic hormone)
84. The effects of prostaglandins
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Questions for the student lab report:
1. Hematocrit
2. Red blood cell counting
3. White blood cell counting
4. Differential leukocyte count
5. Determination of osmotic resistance.
6. Determination of hemoglobin concentration
7. MCV, MCH, MCHC values
8. Prothrombin time
9. Blood group determination (AB0 and Rh typing)
10. Examination of hemoglobin spectra
11. How to use work stations for electrophysiological registrations
12. Recording of heart beats of the frog „in situ”
13. Electric stimulation of heart (demonstr. of extrasystole)
14. Effect of thermal stimulations of frog’s heart.
15. Ligatures of Stannius
16. Investigation of Bowditch’s „All or nothing” law
17. Investigation of summation
18. Electrocardiography (ECG)
19. Examination of the arterial pulse
20. Measurement of blood pressure in human
21. Isolated frog’s heart preparing by Straub cannulla
22. Effect of acethylcholin on isolated frog’s heart
23. Effect of adrenalin on isolated frog’s heart
24. Effect of ions on the isolated heart
25. Direct measurement of blood pressure in cat
26. The circulation through capillaries of frog’s tongue.
27. Pulse wave registration.
28. Spirometry, dynamic parameters of respiration
29. Volumes and capacities of the lungs.
30. Measurement of maximal respiratory pressures (The experiments of Müller and Valsalva)
31. Demonstration of basic respiratory movements and pressure/volume changes (Donders model)
32. Gastric juice: Determination of BAO, MAO, PAO
33. Bile: detection of bile pigments
34. Feces: Detection of blood (Guajac-, benzidin-, Hematest)
35. Measurement of the actual metabolic rate in human
36. Measurement of the oxigen consumption in rat.
37. Specific gravity of urine.
38. Examination of the urine sediment
39. Urine examination with reagent strip methodology
40. Examination of pathological urine components with tests in tubes: protein, glucose, keton bodies, blood, ubg, bilirubin, pus detections
Study material for the semester exam is the sum total of information covered in the obligatory textbook, on the homepage of the Institute,
as well as knowledge given at the lectures and lab practices.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Lengyel Ferenc (LEFAAA.T.JPTE), Kovács Anita (KOAMAET.PTE)
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ATT3-T PHYSICAL EDUCATION 3
Course director: TAMÁS TÉCZELY, physical education teacher
UP MS Sports Facilities
0 credit ▪ signature ▪ Criterion requirement subject ▪ both semesters semester ▪ recommended semester: 3
Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 50 Prerequisites: ATT2-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test: 1
Topic
This subject provides theoretical and practical information for the students to maintain and improve their physical condition and helps to
deepen the knowledge in the field of healthy lifestyle.
Theoretical and practical knowledge during different types of exercises e.g. how to improve endurance, muscle force, motor skills and
how to prevent the body from injuries.
Conditions for acceptance of the semester
Active participation at least 20 practical lessons provided by the Institute of Human Movement Sciences or regular participation of the
trainings of the Medikus Sport Club or PEAC.
Mid-term exams
-
Making up for missed classes
We provide opportunities to attend extra lessons in the first week of the exam period in that case the requirements are not fulfilled till the
end of the teaching weeks with agreement of the PE Teacher.
Reading material
- Obligatory literature
- Literature developed by the Department
Not available.
- Notes
- Recommended literature
Lectures
Practices
1-28 For the list of actual courses please turn to the end of this document
Seminars
Exam topics/questions
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Farkas György (FAGMAAO.PTE), Lipcsik Zoltán (LIZIAAT.PTE), Németh Attila Miklós (NEAGAET.PTE), Téczely Tamás (PETLAAT.PTE)
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OPA-M1E-T INSTRUMENTAL ANALYSIS - THEORY
Course director: DR. FERENC KILÁR, professor
Institute of Bioanalysis
2 credit ▪ semester exam ▪ Basic subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 1 – not limited Prerequisites: OPA-L2E-T completed + OPA-M1G-T parallel
Topic
The theory of instrumental analysis. Basic and modern instrumental techniques for pharmaceutical analysis.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Two written tests (7th and 13th weeks) during the semester. No opportunity for retake of the written tests.
Making up for missed classes
No opportunity for retake of the lectures.
Reading material
- Obligatory literature
- Literature developed by the Department
Material can be downloaded from the website of the Institute of Bioanalysis under the
Educational materials link: http://aok.pte.hu/en/egyseg/oktatas/160 (the username and password
are provided in the lectures).
- Notes
- Recommended literature
D.A. Skoog, F.J. Holler, S.R. Crouch: Principles of Instrumental Analysis, 6th edition, Thomson,
2007
D.G. Watson: Pharmaceutical Analysis, Elsevier
Lectures
1 Basis of creating instrumental signals
Dr. Kilár Ferenc
2 Errors in instrumental analysis, signal collection
Dr. Kilár Ferenc
3 Basic chemometry
Dr. Kilár Ferenc
4 Electroanalysis (potentiometry, conductometry, voltammetry)
Dr. Kilár Ferenc
5 Spectrophotometry
Dr. Kilár Ferenc
6 Spectrophotometry
Dr. Kilár Ferenc
7 Infrared spectroscopy, fluorescence spectroscopy
Dr. Kilár Ferenc
8 Infrared spectroscopy, fluorescence spectroscopy
Dr. Kilár Ferenc
9 Liquid chromatography, HPLC
Dr. Felinger Attila
10 Liquid chromatography, HPLC
Dr. Felinger Attila
11 Gas-chromatography
Dr. Bufa Anita
12 Gas-chromatography
Dr. Poór Viktória
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13 Electrokinetic methods, electrophoresis
Dr. Kilár Ferenc
14 Electrokinetic methods, electrophoresis
Páger Csilla
15 Atomic absorption spectrometry
Dr. Kilár Ferenc
16 Atomic absorption spectrometry
Páger Csilla
17 Nuclear magnetic resonance spectrometry
Dr. Berente Zoltán
18 Nuclear magnetic resonance spectrometry
Dr. Kilár Ferenc
19 Electron paramagnetic resonance spectrometry
Dr. Kilár Ferenc
20 Electron paramagnetic resonance spectrometry
Dr. Dergez Tímea
21 Mass spectrometry
Dr. Kilár Ferenc
22 Mass spectrometry
Dr. Kilár Ferenc
23 Analytical ultracentrifugation
Dr. Kilár Ferenc
24 Analytical ultracentrifugation
Dr. Kilár Ferenc
25 Mössbauer spectroscopy
Dr. Kilár Ferenc
26 ORD, CD, polarimetry
Dr. Kilár Ferenc
27 Thermal analysis
Dr. Kilár Ferenc
28 Thermal analysis
Dr. Kilár Ferenc
Practices
Seminars
Exam topics/questions
Exam topics can be found in the website of the Institute of Bioanalysis under the
Education link: http://aok.pte.hu/en/egyseg/oktatas/160
Examcourse cannot be taken if the practice has not been accepted with „satisfactory” grade. The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from ‘failed’).
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPA-M1G-T INSTRUMENTAL ANALYSIS - PRACTICE
Course director: DR. FERENC KILÁR, professor
Institute of Bioanalysis
3 credit ▪ midsemester grade ▪ Basic subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 42 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 1 – not limited Prerequisites: OPA-L2E-T completed + OPA-M1E-T parallel
Topic
Instrumental analysis practices, which are coupled to the theory of instrumental analysis.
Collection and evaluation of data, and preparation of report using several, major instrumental analytical techniques.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Each practice is preceded with a short written test, and the students should prepare a report of the measurements and the evaluation. A
final grade will be given for the practices, if 75 % of the practices are completed successfully (minimum „satisfactory” grade).
Making up for missed classes
Maximum two absences are allowed, and one absence can be retaken in selected practices.
Reading material
- Obligatory literature
- Literature developed by the Department
Material can be downloaded from the website of the Institute of Bioanalysis under the
Educational materials link: http://aok.pte.hu/en/egyseg/oktatas/160 (the username and password
are provided in the lectures).
- Notes
Instrumental Analysis. Laboratory Practice. DOI: 10.15170/TTK.2014.00001 (dowloadable using the DOI number).
- Recommended literature
D.A. Skoog, F.J. Holler, S.R. Crouch: Principles of Instrumental Analysis, 6th edition, Thomson,
2007
D.G. Watson: Pharmaceutical Analysis, Elsevier
Lectures
Practices
1 Introduction to the laboratory practices.
2 Introduction to the laboratory practices.
3 Introduction to the laboratory practices.
4 Potentiometry
5 Potentiometry
6 Potentiometry
7 Conductometry
8 Conductometry
9 Conductometry
10 Spectrophotometry
11 Spectrophotometry
12 Spectrophotometry
13 Atomic absorption spectrometry
14 Atomic absorption spectrometry
15 Atomic absorption spectrometry
16 Gas-chromatography
17 Gas-chromatography
18 Gas-chromatography
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19 HPLC
20 HPLC
21 HPLC
22 Capillary electrophoresis
23 Capillary electrophoresis
24 Capillary electrophoresis
25 Infrared spectrometry
26 Infrared spectrometry
27 Infrared spectrometry
28 NMR
29 NMR
30 NMR
31 Mass spectrometry
32 Mass spectrometry
33 Mass spectrometry
34 Mass spectrometry
35 Mass spectrometry
36 Mass spectrometry
37 Coupled separation techniques
38 Coupled separation techniques
39 Coupled separation techniques
40 Retake of missing practices
41 Retake of missing practices
42 Retake of missing practices
Seminars
Exam topics/questions
Exam topics can be downloaded from the website of the Institute of Bioanalysis under the
Education link: http://aok.pte.hu/en/egyseg/oktatas/160
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Bufa Anita (BUAEAA.T.JPTE), Dr. Dergez Tímea (DETCAA.T.JPTE), Dr. Felinger Attila (FEANAAP.PTE), Dr. Kilár Ferenc
(KIFGAAO.PTE), Dr. Makszin Lilla (MALHAAT.PTE), Dr. Poór Viktória (POVAAA.T.JPTE), Nagy Laura (NALPACT.PTE), Páger Csilla (PACMAAO.PTE)
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OPA-V2E-T ORGANIC CHEMISTRY 2 - THEORY
Course director: DR. TAMÁS KÁLAI, professor
Department of Organic and Pharmacological Chemistry
3 credit ▪ final exam ▪ Basic subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 42 lectures + 0 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 2 – 80
Prerequisites: OPA-V1E-T completed + OPA-M2E-T completed + OPA-V2G-T parallel
Topic
This subject is a part of chemistry basics. Its aim is to present the nomenclature, structure, physical and chemical properties, synthesis, reaction mechanisms and application of organic compounds.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Students can venture upon the accomplishment of written test two times.
Making up for missed classes
Students have to contact the lecturer of the subject.
Reading material
- Obligatory literature
John McMurry, Eric Simanek: Fundamentals of Organic Chemistry, 6th ed., Thomson Brooks, Belmont, 2007.
- Literature developed by the Department
- Notes
- Recommended literature
T. W. Graham Solomons: Organic Chemistry, 7th edition, Wiley and Sons, New York, 2000.
William H. Brown: Organic Chemistry, Saunders College Publishing, Fort Worth, 1995.
Lectures
1 Nitro compounds: electronic structure, physical, chemical properties, synthesis, reduction of nitro compounds, their nitro-aldol reaction, biologically important nitro compounds.
Dr. Kálai Tamás
2 Nitro compounds: electronic structure, physical, chemical properties, synthesis, reduction of nitro compounds, their nitro-aldol reaction, biologically important nitro compounds.
Dr. Kálai Tamás
3 Nitro compounds: electronic structure, physical, chemical properties, synthesis, reduction of nitro compounds, their nitro-aldol
reaction, biologically important nitro compounds.
Dr. Kálai Tamás
4 Amino compounds: Physical, chemical properties, basicity of amines, their synthesis and reactions.
Dr. Kálai Tamás
5 Amino compounds: Physical, chemical properties, basicity of amines, their synthesis and reactions.
Dr. Kálai Tamás
6 Amino compounds: Physical, chemical properties, basicity of amines, their synthesis and reactions.
Dr. Kálai Tamás
7 Biologically important amines derived from amino acid decarboxylation; Alkaloids: definition and some representatives.
Dr. Kálai Tamás
8 Biologically important amines derived from amino acid decarboxylation; Alkaloids: definition and some representatives.
Dr. Kálai Tamás
9 Biologically important amines derived from amino acid decarboxylation; Alkaloids: definition and some representatives.
Dr. Kálai Tamás
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10 Aldehydes and ketones: electronic structure of carbonyl group, enol-oxo tautomerism, physical, chemical properties, synthesis of aldehydes and ketones, their reactions and some representatives; Quinones, vitamin K.
Dr. Pápayné Dr. Sár Cecília
11 Aldehydes and ketones: electronic structure of carbonyl group, enol-oxo tautomerism, physical, chemical properties, synthesis of aldehydes and ketones, their reactions and some representatives; Quinones, vitamin K.
Dr. Pápayné Dr. Sár Cecília
12 Aldehydes and ketones: electronic structure of carbonyl group, enol-oxo tautomerism, physical, chemical properties, synthesis
of aldehydes and ketones, their reactions and some representatives; Quinones, vitamin K.
Dr. Pápayné Dr. Sár Cecília
13 Carbohydrates: classification of carbohydrates, hemiacetal formation, mutarotation, D- and L-sugars; alpha- and beta-anomers.
Chemical-physical properties of carbohydrates: oxidation, acetylation, bromination, formation of O- and N-glycosides. Epimerization. Formation of fructose 1,6-diphosphate in aldol reaction.
Dr. Pápayné Dr. Sár Cecília
14 Carbohydrates: classification of carbohydrates, hemiacetal formation, mutarotation, D- and L-sugars; alpha- and beta-anomers.
Chemical-physical properties of carbohydrates: oxidation, acetylation, bromination, formation of O- and N-glycosides.
Epimerization. Formation of fructose 1,6-diphosphate in aldol reaction.
Dr. Pápayné Dr. Sár Cecília
15 Carbohydrates: classification of carbohydrates, hemiacetal formation, mutarotation, D- and L-sugars; alpha- and beta-anomers.
Chemical-physical properties of carbohydrates: oxidation, acetylation, bromination, formation of O- and N-glycosides. Epimerization. Formation of fructose 1,6-diphosphate in aldol reaction.
Dr. Pápayné Dr. Sár Cecília
16 Function and structure of oligosaccharides and polysaccharides; Reducing and non-reducing sugars, the invert sugar. Chemical reactions of oligosaccharides.
Dr. Pápayné Dr. Sár Cecília
17 Function and structure of oligosaccharides and polysaccharides; Reducing and non-reducing sugars, the invert sugar. Chemical
reactions of oligosaccharides.
Dr. Pápayné Dr. Sár Cecília
18 Function and structure of oligosaccharides and polysaccharides; Reducing and non-reducing sugars, the invert sugar. Chemical
reactions of oligosaccharides.
Dr. Pápayné Dr. Sár Cecília
19 Carboxylic acids and their derivatives: Electronic structure of carboxylic acids and their derivatives. Formation and reactivity of
carboxylic acid derivatives, acidity of carboxylic acids. Physical and chemical properties of carboxylic acids. Some biologically important carboxylic acids; Structure of lipids and phospholipids.
Dr. Kálai Tamás
20 Carboxylic acids and their derivatives: Electronic structure of carboxylic acids and their derivatives. Formation and reactivity of
carboxylic acid derivatives, acidity of carboxylic acids. Physical and chemical properties of carboxylic acids. Some biologically important carboxylic acids; Structure of lipids and phospholipids.
Dr. Kálai Tamás
21 Carboxylic acids and their derivatives: Electronic structure of carboxylic acids and their derivatives. Formation and reactivity of
carboxylic acid derivatives, acidity of carboxylic acids. Physical and chemical properties of carboxylic acids. Some biologically
important carboxylic acids; Structure of lipids and phospholipids.
Dr. Kálai Tamás
22 Alpha-substituted carboxylic acids: their structure, acidity, biological importance. Carbonic acid derivatives: syntesis, their
utilization in amino acid synthesis and in drug industry.
Dr. Kálai Tamás
23 Alpha-substituted carboxylic acids: their structure, acidity, biological importance. Carbonic acid derivatives: syntesis, their
utilization in amino acid synthesis and in drug industry.
Dr. Kálai Tamás
24 Alpha-substituted carboxylic acids: their structure, acidity, biological importance. Carbonic acid derivatives: syntesis, their
utilization in amino acid synthesis and in drug industry.
Dr. Kálai Tamás
25 Amino acids, peptides: physical and chemical properties of amino acids (zwitterion formation, chirality) peptide link formation, amino acid synthesis, peptide synthesis, structure of proteins, general features of proteins and their classification.
Dr. Kálai Tamás
26 Amino acids, peptides: physical and chemical properties of amino acids (zwitterion formation, chirality) peptide link formation, amino acid synthesis, peptide synthesis, structure of proteins, general features of proteins and their classification.
Dr. Kálai Tamás
27 Amino acids, peptides: physical and chemical properties of amino acids (zwitterion formation, chirality) peptide link formation, amino acid synthesis, peptide synthesis, structure of proteins, general features of proteins and their classification.
Dr. Kálai Tamás
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28 5-Membered heterocycles with one or two heteroatoms: classification of heterocycles, their nomenclature, electronic structure,
aromaticity, aromatic electrophilic substitution, basicity, virtual tautomerism. Most important and biologically important
representatives.
Dr. Kálai Tamás
29 5-Membered heterocycles with one or two heteroatoms: classification of heterocycles, their nomenclature, electronic structure,
aromaticity, aromatic electrophilic substitution, basicity, virtual tautomerism. Most important and biologically important representatives.
Dr. Kálai Tamás
30 5-Membered heterocycles with one or two heteroatoms: classification of heterocycles, their nomenclature, electronic structure,
aromaticity, aromatic electrophilic substitution, basicity, virtual tautomerism. Most important and biologically important representatives.
Dr. Kálai Tamás
31 6-Membered heterocycles with one or two heteroatoms: their nomenclature, basicity, electronic structure, eno-oxo amino-imino
tautomerism, aromatic electrophilic substitution, nucleophilic substitution; Most important and biologically active
representatives.
Dr. Kálai Tamás
32 6-Membered heterocycles with one or two heteroatoms: their nomenclature, basicity, electronic structure, eno-oxo amino-imino
tautomerism, aromatic electrophilic substitution, nucleophilic substitution; Most important and biologically active representatives.
Dr. Kálai Tamás
33 6-Membered heterocycles with one or two heteroatoms: their nomenclature, basicity, electronic structure, eno-oxo amino-imino
tautomerism, aromatic electrophilic substitution, nucleophilic substitution; Most important and biologically active representatives.
Dr. Kálai Tamás
34 Bases of nucleic acids. Structure of nucleic acids, chemical background to mutations.
Dr. Kálai Tamás
35 Bases of nucleic acids. Structure of nucleic acids, chemical background to mutations.
Dr. Kálai Tamás
36 Bases of nucleic acids. Structure of nucleic acids, chemical background to mutations.
Dr. Kálai Tamás
37 Vitamins: classification of vitamins and their biological role.
Dr. Pápayné Dr. Sár Cecília
38 Vitamins: classification of vitamins and their biological role.
Dr. Pápayné Dr. Sár Cecília
39 Vitamins: classification of vitamins and their biological role.
Dr. Pápayné Dr. Sár Cecília
40 Summary
Dr. Pápayné Dr. Sár Cecília
41 Summary
Dr. Pápayné Dr. Sár Cecília
42 Summary
Dr. Pápayné Dr. Sár Cecília
Practices
Seminars
Exam topics/questions
1. Alkanes: Orbital hybridization and the structure of alkanes; Nomenclature, physical and chemical properties, combustion, free radical
chlorination, conformation, cycloalkanes, type of ring strains, demonstrate with examples.
2. Unsaturated hydrocarbons: sp2 and sp hybridization, nomenclature, physical properties, reactions and synthesis of alkenes and alkynes.
Electrophilic addition, Markovnikov’s rule, 1,2- and 1,4-addition, conjugated and cumulated dienes.
3. Importance of unsaturated hydrocarbons in industry and biology: polymerization, isoprene, terpenes, steroids, carotenoids, polymers, rubber
4. Aromatic compounds: the structure of benzene, Hückel’s rule. Electrophilic aromatic substitution reactions. (Nitation, sulfonation,
bromination, Friedel-Crafts reactions), direction rules, classification of substituents, polyaromatics: examples, their chemical reactions aromatic electophilic substitution, oxidation.
5. Alkyl halides: the character of C-X bonds, physical properties, reactivity of alkyl halides, synthesis of alkyl and aromatic halides, and reactions of alkyl halides (substitution, elimination); Organic halides in the environment.
6. Organometallic compounds: their structure, their importance in organic syntheses (Mg, Na, Li, Si, Cu, Cd compounds).
7. Alcohols, phenols, ethers: Structure, physical and chemical properties, reactions; Their biological importance.
8. Stereochemistry: isomerism, absolute and relative configuration, chirality, racemates, diastereomers, polarimetry, resolution.
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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9. Sulfur containing compounds: Physical, chemical properties, importance in biological processes (in amino acids, peptides, methylation in biology, AcCo-A, drugs, sulfonamides, penicillin, cefalosporin).
10. Nitro compounds: electronic structure, physical, chemical properties, synthesis (including aromatic electrophilic nitration), reduction
of nitro compounds, their nitro-aldol reaction, biologically important nitro compounds (glycerine trinitrate, chloroamphenicol).
11. Amino compounds - Physical, chemical properties, basicity of amines (compare aniline, ammonia, methylamine, dimethylamine etc.)
their possible synthesis (alkylation of ammonia, Gabriel synthesis, reductive amination, Hofmann rearrangement), reactions: Hinsberg reaction, oxidation of amines, reaction with HNO2.
12. Biologically important amines: structure and properties of histamine, tryptamine, choline, acetylcholine, taurine, putrescine, adrenaline; Alkaloids: definition (structure of mescaline, nicotine, coniine, quinine, papaverine, morphine)
13. Aldehydes and ketones: electronic structure of carbonyl group, enol-oxo tautomerism, physical, chemical properties, synthesis of
aldehydes and ketones, their reaction: aldol condensation, Canizzaro-reaction, Silver mirror/Fehling test, oxidation, reaction with amines, hydrazines, Grignard-reagent, oximes, Beckmann-rearrangement, ketenes, quinones, vitamin K.
14. Carbohydrates: classification of carbohydrates (ketose, aldose, pyranose, furanose, pentose, hexose), hemiacetal formation,
mutarotation, D- and L-sugars; alpha- and beta-anomers. Chemical-physical properties of carbohydrates. The following covalent
structures are required: glucose, fructose, mannose, galactose, ribose, 2-deoxy-ribose, glyceraldehyde, ascorbic acid. Oxidation of
carbohydrates, acetylation, bromination, formation of O- and N-glycosides. Epimerization (glucose, mannose, fructose). Formation of fructose 1,6-diphosphate in aldol reaction.
15. Function and structure of oligosaccharides and polysaccharides: sucrose, maltose, cellobiose, lactose, kitine, pectine, cellulose, starch.
Reducing sugars and non-reducing sugars, the invert sugar. Chemical reactions of oligosaccharides.
16. Carboxylic acids and their derivatives (acyl chlorides, anhydrides, esters, amides): Electronic structure of carboxylic acids and their
derivatives. Formation of carboxylic acids and their derivatives. Reactivity of carboxylic acid derivatives, acidity of carboxylic acids.
Physical and chemical properties of carboxylic acids. Ester synthesis, Claisen-condensation. Most important carboxylic acids: formic acid, acetic acid, benzoic acid, oleic acid, linolic and linoleic acid, palmitic and stearic acids, structure of lipids and phospholipids.
17. Alpha-substituted carboxylic acids and carbonic acid: halogenation, lactic acid, pyruvic acid, malonic acid, malonic acid synthesis,
oxalic acid, malic acid, maleic acid, fumaric acid, citric acid. Their structure, acidity, biological importance. Carbonic acid
derivatives: carbonic acid and its esters, phosgene, chloroformic acid esters and their utilization in amino acid synthesis, urea, thiourea, diureides, barbituric acid and its derivatives, guanidine, creatine.
18. Amino acids, peptides: the exact covalent structure of 20 amino acids, physical and chemical properties (zwitterion formation,
chirality) peptide link formation, amino acid synthesis, glutathione, peptide synthesis, structure of proteins (primary, secondary,
tertiary, quaternary), general features of proteins, their classification with examples, denaturation and colour-reactions of proteins (Xantoprotein-test, Millon-test etc.)
19. 5-Membered heterocycles: classification of heterocycles, their nomenclature, most important representatives: furane, thiophene,
pyrrole. Heterocycles with two heteroatoms: oxazole, thiazole, imidazole, their electronic structure, aromaticity, aromatic
electrophilic substitution, basicity, virtual tautomerism. Biologically important representatives: biotin, ultraseptil, histamine, penicillins, aminophenazone, furfural; Indole and its derivatives: serotonine, auxins, indigo.
20. 6-Membered heterocycles: their nomenclature, most important representatives: pyridine, quinoline, isoquinoline, pyrilium,
benzpyrilium cation, their basicity, electronic structure, eno-oxo amino-imino tautomerism, aromatic electrophilic substitution,
nucleophilic substitution, biologically important derivatives: rutin, vitamin E, cyanidium chloride, tetrahydrocannabinol,
nicotinamide, quinine, papaverine, vitamin B6, isoniazide, nifedipine, barbituric acid: veronal, sevenal bases of nucleic acids, base
pairs cytosine, guanine, adenine, timine, uracil, their exact covalent structure, structure of DNA, RNA, vitamin B1, purine: caffeine, theophylline, theobromine, xanthine, pteridine, structure and function of folic acid.
21. Vitamins: classification of vitamins, their exact covalent structure, their biological role. Vitamin A, vitamin D, Vitamin E, vitamin
K, Vitamin B1, Vitamin B3, Vitamin B5, the role and function of the NAD, Vitamin B6, Vitamin B7, inosite, p-aminobenzoic acid,
folic acid, Vitamin B12, Vitamin C, Vitamin P and flavonoids, Vitamin U.
The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the
result different from failed)
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
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OPA-V2G-T ORGANIC CHEMISTRY 2 - PRACTICE
Course director: DR. TAMÁS KÁLAI, professor
Department of Organic and Pharmacological Chemistry
3 credit ▪ midsemester grade ▪ Basic subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 42 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 2 – 80 Prerequisites: OPA-V1E-T completed
Topic
The aims of this course are to introduce students into several basic laboratory techniques and to demonstrate some characteristic reactions of organic compounds with various functional groups.
Conditions for acceptance of the semester
During the semester students have to accomplish the preparative works and written tests. They have to document the experiments in their
exercise book.
Mid-term exams
The organic chemistry laboratory course will be graded (1-5), based on the two written tests on 6th and 11th week, first of all. The
evaluation can be modified by grades of semi-micro preparations, success of unknown identification as well as the outlook of the records
of exercise book.
Making up for missed classes
Students have to contact their lab TA within 48 hours of missing lab to make the necessary arrangements.
Reading material
- Obligatory literature
- Literature developed by the Department
Kálai, T., Bognár, B. Organic Chemisry Laboratory Manual, Dept. of Org. and Med. Chem., Medical Faculty, University of Pécs, 2010.
- Notes
- Recommended literature
Charles F. Wilcox, Jr., Mary F. Wilcox: Experimental Organic Chemistry: a Small-scale Approach, 2nd ed., Prentice-Hall, London, 1995.
Dana W. Mayo, Ronald M. Pike, Peter K. Trumper: Microscale Organic Laboratory with Multistep and Multiscale Syntheses, 3rd ed., Wiley, New York, 1994.
Lectures
Practices
1 General instructions for work in the laboratory, safety precautions; Purification of benzaldehyde, synthesis of benzoin.
2 General instructions for work in the laboratory, safety precautions; Purification of benzaldehyde, synthesis of benzoin.
3 General instructions for work in the laboratory, safety precautions; Purification of benzaldehyde, synthesis of benzoin.
4 Synthesis of 2,6-dibenzylidene-cyclohexanone; Characteristic tube reactions of oxo compounds.
5 Synthesis of 2,6-dibenzylidene-cyclohexanone; Characteristic tube reactions of oxo compounds.
6 Synthesis of 2,6-dibenzylidene-cyclohexanone; Characteristic tube reactions of oxo compounds.
7 Synthesis of benzil; Identification of 4th unknown compound.
8 Synthesis of benzil; Identification of 4th unknown compound.
9 Synthesis of benzil; Identification of 4th unknown compound.
10 Characteristic tube reactions of carbohydrates; Preparation of oxalic acid, isolation of citric acid.
11 Characteristic tube reactions of carbohydrates; Preparation of oxalic acid, isolation of citric acid.
12 Characteristic tube reactions of carbohydrates; Preparation of oxalic acid, isolation of citric acid.
13 Acetylation of glucose; Identification of 5th unknown compound;
14 Acetylation of glucose; Identification of 5th unknown compound;
15 Acetylation of glucose; Identification of 5th unknown compound;
16 1st written test; Synthesis of aspirin. Polarimetry.
17 1st written test; Synthesis of aspirin. Polarimetry.
18 1st written test; Synthesis of aspirin. Polarimetry.
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19 Synthesis of lidocain (1st step); Characteristic tube reactions of carboxylic acids and carboxylic acid derivatives.
20 Synthesis of lidocain (1st step); Characteristic tube reactions of carboxylic acids and carboxylic acid derivatives.
21 Synthesis of lidocain (1st step); Characteristic tube reactions of carboxylic acids and carboxylic acid derivatives.
22 Synthesis of lidocain (2nd step);
23 Synthesis of lidocain (2nd step);
24 Synthesis of lidocain (2nd step);
25 Synthesis of heterocycles I. (five membered): benzimidazole, dilantin; Characteristic tube reactions of pyridine.
26 Synthesis of heterocycles I. (five membered): benzimidazole, dilantin; Characteristic tube reactions of pyridine.
27 Synthesis of heterocycles I. (five membered): benzimidazole, dilantin; Characteristic tube reactions of pyridine.
28 Synthesis of heterocycles II. (six membered): 4-phenyl-5-carbethoxy-6-methyl-1,2,3,4-tetrahyropyrimidin-2-one, 4-methyl-7-
hydroxycoumarine.
29 Synthesis of heterocycles II. (six membered): 4-phenyl-5-carbethoxy-6-methyl-1,2,3,4-tetrahyropyrimidin-2-one, 4-methyl-7-
hydroxycoumarine.
30 Synthesis of heterocycles II. (six membered): 4-phenyl-5-carbethoxy-6-methyl-1,2,3,4-tetrahyropyrimidin-2-one, 4-methyl-7-
hydroxycoumarine.
31 2nd written test. Isolation of caffeine.
32 2nd written test. Isolation of caffeine.
33 2nd written test. Isolation of caffeine.
34 Isolation of quercetin and myristic acid.
35 Isolation of quercetin and myristic acid.
36 Isolation of quercetin and myristic acid.
37 Characteristic tube reactions of amino acids and peptides.
38 Characteristic tube reactions of amino acids and peptides.
39 Characteristic tube reactions of amino acids and peptides.
40 Evaluation.
41 Evaluation.
42 Evaluation.
Seminars
Exam topics/questions
The written tests will contain the matter of practice.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Bognár Balázs (BOBGAAT.PTE), Dr. Kálai Tamás (KATFABP.PTE), Dr. Pápayné Dr. Sár Cecília (PASFADP.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPG-GI1-T BASIC PRINCIPLES OF PHARMACY
Course director: DR. LAJOS BOTZ, professor
Department of Pharmaceutics and University Pharmacy
2 credit ▪ midsemester grade ▪ Pharm. theoretical module and practical skills subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 28 lectures + 0 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – 50 Prerequisites: OPO-GB2-T completed
Topic
The basic aims of the course are to provide fundamental knowledge of pharmaceutics and gain insight into the pharmaceutical profession.
The subject will support further studies and the summer professional practice by improving vocabulary, professional knowledge, etc..
Further goals are to draw the attention of students towards specific topics (professionalism, roles of pharmacists in healthcare) of pharmacy, to help students gain interest in practical aspects of pharmaceutical work and to introduce further professional studies.
The course gives an overview of the basic principles of pharmacy and pharmaceuticals. Definitions of the different groups of
pharmaceuticals, synopsis of the process of drug development, evolution and role of pharmacopoeias, sites and aims of small-, medium-
and large scale drug manufacturing, the role of community and clinical pharmacies. During the semester several on-site visits will be
organized to familiarize students with the different fields of pharmacists.
Attendance of, and active participation in the lectures, furthermore understanding of given topics are the basic requirements of completing
the course. Students shall hold a short presentation regarding a previously discussed topic and shall take attend the on site visits organized
by the Institute (community pharmacy, clinical and hospital pharmacy, pharmaceutical industry). Topics discussed during the lectures,
but not included in the notes/books will also be included in the exams. Students can access the slides of the lectures and further reading material on a designated web based interface (Neptun Meet Street). Prior knowledge from earlier theoretical studies is an advantage.
Conditions for acceptance of the semester
- Regular attendance of classes/lectures (maximum 25 % of absence is accepted),
- Assignments given in class should be carried out during term-time and,
- The mid-term and end-of-the-term test(s) should be passed (60,1%, minimum grade 2).
Mid-term exams
End-of-semester grade is given by end-of-the-term test’s result, any tests written throughout the semester and student performance during
the semester.
Examination and granting of grades: for Basic Principles of Pharmacy grade (midterm grade) is given based on mid-term and end-of-
the-term test results.
Retake opportunity is possible following personal discussion.
Making up for missed classes
Retake opportunity is possible following personal discussion.
Reading material
- Obligatory literature
- Literature developed by the Department
All presentations can be downloaded from Neptun Meet Street.
- Notes
- Recommended literature
Christopher A Langley, Dawn Belcher: Applied Pharmaceutical Practice, 2nd edition, Pharmaceutical Press 2012
Medicines, Ethics and Practice: The Professional Guide for Pharmacists, 36th edition, Royal Pharmaceutical Society of Great Britain, 2012
Lectures
1 Introduction to Basic Principles of Pharmacy. Short presentation of the Department of Pharmaceutics & Central Clinical
Pharmacy
Dr. Fittler András Tamás
2 Pharmacy as a profession. Areas of pharmacy practice
Dr. Fittler András Tamás
3 Introduction of the product categories found in community pharmacies
Dr. Fittler András Tamás
4 Routes of administration
Dr. Fittler András Tamás
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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5 Classification of medications
Dr. Fittler András Tamás
6 How active substances and medicines are named. Index Nominum
Dr. Fittler András Tamás
7 Pharmacopoeias and Formularies
Dr. Fittler András Tamás
8 Contents and format of the medical prescription
Dr. Fittler András Tamás
9 Handling of the prescription by the pharmacist: Pharmacy Practice Procedures
Dr. Fittler András Tamás
10 Labelling of dispensed medicines
Dr. Fittler András Tamás
11 Latin terms and abbreviations, pharmaceutical calculations
Dr. Fittler András Tamás
12 On site visit to the Central Clinical Pharmacy
Dr. Lankó Erzsébet
13 Getting familiar with ingredients and dosage forms of pharmaceuticals made in pharmacies
Dr. Mayer Anna
14 Manufacturing of medicines and the importance of good manufacturing practice
Dr. Fittler András Tamás
15 Structure and tasks of a community pharmacy
Dr. Fittler András Tamás
16 Structure and tasks of a community pharmacy. On site visit
Dr. Fittler András Tamás
17 Structure and tasks of a clinical pharmacy
Dr. Fittler András Tamás
18 Structure and tasks of a clinical pharmacy. On site visit
Dr. Fittler András Tamás
19 Research and development of medicines
Dr. Vida Róbert György
20 Clinical trials
Dr. Vida Róbert György
21 Structure and tasks of the pharmaceutical industry
Dr. Fittler András Tamás
22 Structure and tasks of the pharmaceutical industry. On site visit
Dr. Fittler András Tamás
23 Oral presentations of students on pre-arranged topics 1
Dr. Fittler András Tamás
24 Oral presentations of students on pre-arranged topics 2
Dr. Fittler András Tamás
25 History of Pharmacy and Medicine (1) from the ancient world to 1100 AD.
Dr. Fittler András Tamás
26 History of Pharmacy and Medicine (2) in the medieval world form 1100 to 1617 AD.
Dr. Fittler András Tamás
27 History of Pharmacy and Medicine (3) in the modern world 1841-1986.
Dr. Végh Anna
28 Where are we heading? Pharmacy in the 21st century. Test
Dr. Végh Anna
Practices
Seminars
Exam topics/questions
Based on the topics of the lectures.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPO-G1B-T PHARMACEUTICAL BIOCHEMISTRY 1
Course director: DR. KATALIN SIPOS, associate professor
Department of Forensic Medicine
3 credit ▪ semester exam ▪ Med.-biol. theoretical module and practical skills subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 28 lectures + 0 practices + 14 seminars = total of 42 hours
Course headcount limitations (min.-max.): 5 – not limited Prerequisites: OPA-L1E-T completed + OPA-AM1-T completed
Topic
The two-semester biochemistry course provides the essential fundamental biochemistry knowledge for the pharmaceutical students. This
course deals with the metabolic pathways of the living cell: the reactions, steps and regulation of these pathways. In the first semester
students will be introduced to the life of the basic synthetic and anabolic biochemical pathways and they will study how energy is produced in the cell. We will pay special attention to enzymes: their features, regulations, roles in the drug metabolism and action.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
There are two mid-term exams. The results of them is included in the result of the exam.
Making up for missed classes
According to personal agreement
Reading material
- Obligatory literature
- Literature developed by the Department
The materials of the lectures and seminars will appear on Neptune.
- Notes
The e-notes of Biochemistry will appear on Neptune.
- Recommended literature
Ch. P. Woodbury: Biochemistry for the Pharmaceutical Sciences
Raymond S. Ochs: Biochemistry
Thomas M. Devlin: Textbook of Biochemistry with Clinical Correlations
Lectures
1 Introduction
Dr. Sipos Katalin
2 Thermodynamics, biochemical reactions
Dr. Sipos Katalin
3 Biomembranes. Transport processes I
Dr. Sipos Katalin
4 Transport processes II
Dr. Sipos Katalin
5 Enzymes: characteristics, types, catalytic activities
Dr. Sipos Katalin
6 Proteases
Dr. Pandur Edina
7 Basic regulatory mechanisms in metabolism
Dr. Sipos Katalin
8 Glycolysis
Dr. Farkas Viktória
9 Gluconeogenesis
Dr. Farkas Viktória
10 Glycogen metabolism
Dr. Farkas Viktória
11 Cori cycle
Dr. Farkas Viktória
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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12 Pentose phosphate pathway
Dr. Farkas Viktória
13 Metabolism of complex carbohydrates
Dr. Sipos Katalin
14 Pyruvate dehydrogenase complex
Dr. Farkas Viktória
15 Citric acid cycle
Dr. Farkas Viktória
16 Mitochondrial transport processes
Dr. Farkas Viktória
17 Terminal oxidation, ATP synthesis I
Dr. Farkas Viktória
18 Terminal oxidation, ATP synthesis II
Dr. Farkas Viktória
19 Degradation of lipids
Dr. Sipos Katalin
20 Ketone bodies
Dr. Farkas Viktória
21 Biosynthesis of fatty acids
Dr. Farkas Viktória
22 Biosynthesis of complex lipids
Dr. Sipos Katalin
23 Cholesterol metabolism I
Dr. Farkas Viktória
24 Cholesterol metabolism II
Dr. Farkas Viktória
25 Characterization of amino acids
Pap Ramóna
26 Nucleic acids: building blocks, structures
Pap Ramóna
27 Preparation for exam
Dr. Sipos Katalin
28 Preparation for exam
Dr. Sipos Katalin
Practices
Seminars
1 Macromolecules in biochemistry
2 Nutrition and vitamins in biochemistry
3 Carbohydrates: biochemical characterization. Carbohydrates in the extracellular space
4 Clinical importance of carbohydrates
5 Regulation of enzymes
6 Enzymekinetics. Inhibition of enzymes
7 Structure, folding and degradation of proteins
8 Lipids: phospholipids, sphingolipids, cholesterol, fatty acids
9 Clinical importance of lipids
10 Clinical consequences of terminal oxidation.
11 Carbohydrate metabolism
12 Lipid metabolism
13 Enzyme inhibiting drugs
14 Preparation for exam
Exam topics/questions
There are no given exam questions. The topics of the exam will be the materials of lectures and seminars.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Farkas Viktória (FAVSAAP.PTE), Dr. Pandur Edina (PAEFAA.T.JPTE), Dr. Sipos Katalin (SIKMAAO.PTE), Pap Ramóna
(PARTAAT.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPO-G2E-T PHARMACOBOTANY 2 - THEORY
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy
1 credit ▪ semester exam ▪ Med.-biol. theoretical module and practical skills subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 14 lectures + 0 practices + 0 seminars = total of 14 hours
Course headcount limitations (min.-max.): 3 – 100 Prerequisites: OPO-G1E-T completed + OPO-G2G-T parallel
Topic
Pharmacobotany covers all pharmaceutical aspects of botany, including cytology, histology, morphology and taxonomy of plants. Plant
systematics discusses the geographical origin of plant species, the possibilities of cultivation and nature conservation. A special emphasis
is laid on chemotaxonomic aspects, since the medicinal effect of a plant is often related to its taxonomic classification and chemical
characteristics. Practical instruction focuses on the knowledge of medicinal plants, including the confident usage of plant identification
keys. Based on their knowledge of histology and morphology, students are required to apply proper anatomical terms, and finally identify
plant species (taxa). The thorough knowledge of both general and specific pharmacobotany is a prerequisite of studying pharmacognosy.
Conditions for acceptance of the semester
Maximum of 25 % absence allowed
Mid-term exams
Students have to pass (min. 60%) two written exams based on lecture materials. If necessary, students will be provided maximum two
extra chances (B and C chance) besides the original exam date (A chance).
Making up for missed classes
Lecture materials can be downloaded from the website of the Department of Pharmacognosy (Educational Materials).
Reading material
- Obligatory literature
Á. Farkas: Pharmacobotany 2. University of Pécs, Institute of Pharmacognosy, Pécs, 2018
- Literature developed by the Department
Farkas Á., Papp N., Bencsik T., Horváth Gy.: Digital Herbarium and Drug Atlas, electronic learning material, 2014 TÁMOP-4.1.2.A/1-11/1-2011-0016
- Notes
- Recommended literature
Z. Yaniv, U. Bachrach (eds.): Handbook of Medicinal Plants, Haworth Press Inc., 2005
WHO Monographs on Selected Medicinal Plants, Vol. 1. (1999), Vol. 2. (2002)
Lectures
1 Algae (Phaeophyceae, Rhodophyceae), Fungi, Lichenes
Dr. Farkas Ágnes
2 Pteridophyta, Coniferophytina, Cycadophytina. Magnoliidae.
Dr. Farkas Ágnes
3 Caryophyllidae
Dr. Farkas Ágnes
4 Hamamelididae
Dr. Farkas Ágnes
5 Rosidae I.
Dr. Farkas Ágnes
6 Rosidae II.
Dr. Farkas Ágnes
7 Dilleniidae
Dr. Farkas Ágnes
8 Cornidae
Dr. Farkas Ágnes
9 Lamiidae I.
Dr. Farkas Ágnes
10 Lamiidae II.
Dr. Farkas Ágnes
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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11 Asteridae
Dr. Farkas Ágnes
12 Alismatidae. Liliidae.
Dr. Farkas Ágnes
13 Zingiberidae
Dr. Farkas Ágnes
14 Commelinidae, Arecidae
Dr. Farkas Ágnes
Practices
Seminars
Exam topics/questions
The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the
result different from failed).
Final exam:
Entrance exam:
Preceding the oral exam, 6 medicinal plants (5 herbarium specimens, 1 plant from the medicinal plant garden) should be identified and
their brief morphological characterization should be given.
Oral exam:
Following the successful entrance exam, students are required to present their knowledge on 2 topics from the list below. The general
characterization of plant families should be followed by the morphological and chemotaxonomic description of the species belonging to the given families.
Exam questions:
1. Algae, Fungi, Lichenes
2. Lycopodiaceae, Equisetaceae, Aspidiaceae, Polypodiaceae
3. Ginkgoaceae, Abietaceae, Cupressaceae, Taxaceae, Ephedraceae
4. Myristicaceae, Illiciaceae, Lauraceae, Piperaceae, Aristolochiaceae
5. Berberidaceae, Ranunculaceae (Helleboraceae)
6. Papaveraceae, Fumariaceae
7. Chenopodiaceae, Caryophyllaceae, Polygonaceae
8. Hamamelidaceae, Fagaceae, Betulaceae (Corylaceae), Juglandaceae
9. Droseraceae, Rosaceae
10. Mimosaceae, Caesalpiniaceae, Fabaceae
11. Myrtaceae, Punicaceae, Lythraceae, Onagraceae
12. Rutaceae, Anacardiaceae
13. Hippocastanaceae, Geraniaceae, Linaceae, Erythroxylaceae
14. Polygalaceae, Krameriaceae, Rhamnaceae, Vitaceae, Loranthaceae
15. Araliaceae, Apiaceae
16. Violaceae, Passifloraceae, Caricaceae, Cucurbitaceae
17. Brassicaceae, Salicaceae
18. Tiliaceae, Sterculiaceae, Malvaceae
19. Moraceae, Cannabaceae
20. Urticaceae, Euphorbiaceae
21. Elaeagnaceae, Theaceae, Hypericaceae, Primulaceae
22. Aquifoliaceae, Caprifoliaceae (Sambucaceae), Valerianaceae, Ericaceae
23. Loganiaceae, Rubiaceae
24. Apocynaceae, Gentianaceae, Menyanthaceae, Oleaceae
25. Solanaceae, Convolvulaceae
26. Boraginaceae, Scrophulariaceae
27. Plantaginaceae, Pedaliaceae, Verbenaceae
28. Lamiaceae
29. Lobeliaceae, Asteraceae (Cichoriaceae)
30. Dioscoreaceae, Convallariaceae, Asparagaceae, Ruscaceae, Agavaceae
31. Asphodelaceae, Hyacinthaceae, Alliaceae
32. Amaryllidaceae, Melanthiaceae, Colchicaceae, Iridaceae, Orchidaceae
33. Zingiberaceae, Bromeliaceae, Poaceae, Arecaceae
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
45
OPO-G2G-T PHARMACOBOTANY 2 - PRACTICE
Course director: DR. ÁGNES FARKAS, associate professor
Department of Pharmacognosy
2 credit ▪ midsemester grade ▪ Med.-biol. theoretical module and practical skills subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 3 – 100 Prerequisites: OPO-G1E-T completed
Topic
Pharmacobotany covers all pharmaceutical aspects of botany, including cytology, histology, morphology and taxonomy of plants. Plant
systematics discusses the geographical origin of plant species, the possibilities of cultivation and nature conservation. A special emphasis
is laid on chemotaxonomic aspects, since the medicinal effect of a plant is often related to its taxonomic classification and chemical
characteristics. Practical instruction focuses on the knowledge of medicinal plants, including the confident usage of plant identification
keys. Based on their knowledge of histology and morphology, students are required to apply proper anatomical terms, and finally identify
plant species (taxa). The thorough knowledge of both general and specific pharmacobotany is a prerequisite of studying pharmacognosy.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
From the 2nd week onwards, students have to write a short test each week (recognising and characterising medicinal plants).
In the practice, students have to take notes and prepare drawings based on macroscopic and microscopic examinations. Students have to
show their lab notebook to the practice leader, who acknowledges fulfillment of the practice by his/her signature.
The grade for the practice will be made up by the grades from each week’s test and the lab notebook.
Making up for missed classes
Missed practicals can be made up either by joining the other groups or taking extra time at the following lab practical. In all cases,
students must make arrangements with their lab instructors in advance.
Reading material
- Obligatory literature
Á. Farkas: Pharmacobotany 2. University of Pécs, Institute of Pharmacognosy, Pécs, 2018
N. Papp: Pharmacobotany Practices. University of Pécs, Institute of Pharmacognosy, Pécs, 2011
- Literature developed by the Department
Farkas Á., Papp N., Bencsik T., Horváth Gy.: Digital Herbarium and Drug Atlas, electronic learning material, 2014 TÁMOP-4.1.2.A/1-11/1-2011-0016
- Notes
- Recommended literature
Z. Yaniv, U. Bachrach (eds.): Handbook of Medicinal Plants, Haworth Press Inc., 2005
Lectures
Practices
1 Fungi: Morphology of Ganoderma lucidum, Fomes fomentarius and Lentinus edodes. Lichenes: Morphological comparison of Cladonia pyxidata and Cetraria islandica.
2 Pteridophyta: Spores and sporangia of Lycopodium clavatum and Equisetum arvense; rhizome of Dryopteris filix-mas.
3 Spermatophyta: Coniferophytina: Cross section of Ginkgo leaf. Inflorescences, needles and wood of Pinus nigra. Angiospermatophytina: Dicotyledonopsida: Magnoliidae: Aristolochiaceae.
4 Ranunculaceae, Helleboraceae. Helleborus leaf and aggregate of follicles.
5 Berberidaceae. Papaveraceae - Papaver sp. pistil and fruit. Fumariaceae.
6 Caryophyllidae: Phytolaccaceae. Polygonaceae: leaf morphology of Rumex sp. Caryophyllaceae - leaf arrangement, Saponaria officinalis root.
7 Hamamelididae: Fagaceae - leaf morphology and fruit types of Fagus and Quercus species. Betulaceae. Juglandaceae - Juglans regia fruit.
8 Rosidae I.: Grossulariaceae, Crassulaceae. Plant identification practice with identification key.
9 Rosidae II: Rosaceae - Rosaceae flower and fruit types. Pseudofruit of Rosa canina and Malus domestica.
10 Fabaceae - morphology of the flower, leaf and fruit. Leaf and fruit of Laburnum, Medicago and Sophora.
11 Rosidae III: Araliaceae: Morphological features of Hedera helix and Panax ginseng. Apiaceae: compound umbel, double achene.
12 Punicaceae, Lythraceae, Onagraceae, Rutaceae. Hesperidium of Citrus limon.
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13 Rosidae IV: Anacardiaceae, Hippocastanaceae, Geraniaceae. Celastraceae: cork structures on shoots of Euonymus sp. Rhamnaceae.
14 Vitaceae, Loranthaceae, Violaceae, Cucurbitaceae. Dilleniidae: Brassicaceae - silique and silicle. Salicaceae.
15 Dilleniidae: Tiliaceae - leaf morphology of Tilia sp. Cannabaceae - bifid hairs and glandular scales of Humulus lupulus.
16 Malvaceae, Moraceae. Urticaceae: Urtica dioica stinging hairs. Euphorbiaceae - cyathium inflorescence. Elaeagnaceae: stellate hairs of Elaeagnus angustifolia. Hypericaecae, Primulaceae.
17 Cornidae: Caprifoliaceae - Sambucus nigra shoot. Valerianaceae, Rubiaceae. Apocynaceae. Asclepiadaceae. Oleaceae - fruit
types.
18 Plant identification practice.
19 Lamiidae I.: Solanaceae: fruit types. Plantaginaceae : leaf morphology of Plantago sp.
20 Boraginaceae - non-glandular trichomes. Scrophulariaceae - Verbascum phlomoides hairs. Verbenaceae.
21 Lamiidae II.: Lamiaceae.
22 Shoot and leaf morphology of Lamiaceae species. Structure of a Lamiaceae flower.
23 Asteridae: Asteraceae
24 Asteraceae: capitulum types.
25 Monocotyledonopsida: Dioscoreaceae, Convallariaceae, Asparagaceae, Ruscaceae.
26 Alliaceae, Orchidaceae, Poaceae. Morphological distinction of Allium ursinum and Convallaria majalis.
27 Visit to the botanical garden.
28 Visit to the medicinal plant garden.
Seminars
Exam topics/questions
1. Algae, Fungi, Lichenes
2. Lycopodiaceae, Equisetaceae, Aspidiaceae, Polypodiaceae
3. Ginkgoaceae, Abietaceae, Cupressaceae, Taxaceae, Ephedraceae
4. Myristicaceae, Illiciaceae, Lauraceae, Piperaceae, Aristolochiaceae
5. Berberidaceae, Ranunculaceae (Helleboraceae)
6. Papaveraceae, Fumariaceae
7. Chenopodiaceae, Caryophyllaceae, Polygonaceae
8. Hamamelidaceae, Fagaceae, Betulaceae (Corylaceae), Juglandaceae
9. Grossulariaceae, Crassulaceae, Droseraceae, Rosaceae
10. Mimosaceae, Caesalpiniaceae, Fabaceae
11. Myrtaceae, Punicaceae, Lythraceae, Onagraceae
12. Rutaceae, Anacardiaceae
13. Hippocastanaceae, Geraniaceae, Linaceae, Erythroxylaceae
14. Polygalaceae, Krameriaceae, Rhamnaceae, Vitaceae, Loranthaceae
15. Araliaceae, Apiaceae
16. Violaceae, Passifloraceae, Caricaceae, Cucurbitaceae
17. Brassicaceae, Salicaceae
18. Tiliaceae, Sterculiaceae, Malvaceae
19. Moraceae, Cannabaceae
20. Urticaceae, Euphorbiaceae
21. Elaeagnaceae, Theaceae, Hypericaceae, Primulaceae
22. Aquifoliaceae, Caprifoliaceae (Sambucaceae), Valerianaceae, Ericaceae
23. Loganiaceae, Rubiaceae
24. Apocynaceae, Gentianaceae, Menyanthaceae, Oleaceae
25. Solanaceae, Convolvulaceae
26. Boraginaceae, Scrophulariaceae
27. Plantaginaceae, Pedaliaceae, Verbenaceae
28. Lamiaceae
29. Lobeliaceae, Asteraceae (Cichoriaceae)
30. Dioscoreaceae, Convallariaceae, Asparagaceae, Ruscaceae, Agavaceae
31. Asphodelaceae, Hyacinthaceae, Alliaceae
32. Amaryllidaceae, Melanthiaceae, Colchicaceae, Iridaceae, Orchidaceae
33. Zingiberaceae, Bromeliaceae, Poaceae, Arecaceae
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Farkas Ágnes (FAADAB.T.JPTE), Dr. Papp Nóra (PANAAA.T.JPTE)
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OPO-H2E-T HUMAN PHYSIOLOGY 2 - THEORY
Course director: DR. ZOLTÁN KARÁDI, professor
Institute of Physiology
3 credit ▪ final exam ▪ Med.-biol. theoretical module and practical skills subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 42 lectures + 0 practices + 0 seminars = total of 42 hours
Course headcount limitations (min.-max.): 5 – not limited Prerequisites: OPO-H1E-T completed + OPO-H2G-T parallel
Topic
The most important mission of the Physiology Course in medical education is to familiarize students with the attributes of healthy functions of the living organism.
While acquiring knowledge about the most important functional characteristics of the human body the students can rely on their prior
studies in biology, biophysics, chemistry-biochemistry and anatomy.
During the semester we introduce the most important elements of functioning of the organs and organ systems, as well as their cooperation also required to adapting to the environment, and the factors affecting these processes.
Special emphasis is placed on the neural and humoral regulatory processes of these life-functions, which are vital to maintain and preserve the homeostasis of the organism.
With the transfer of all this knowledge we would like to mould a holistic attitude and thinking of students, which will enable them to better understand the functions of the now healthy, however, later dysfunctional human organism.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written test on the 11th week Friday at 16:00.
Making up for missed classes
The missed lab practice is advised to be covered by joining another group while the same topic is on schedule.
Reading material
- Obligatory literature
J.E. Hall: Guyton and Hall Textbook of Medical Physiology, 12th edition, 2013
- Literature developed by the Department
Figures of the lectures given are available on the homepage of Institute of Physiology and on the Neptun Meet Street.
Important messages on new information will be announced at the lectures and will be sent to you by course mails.
Please always find the current updated information and study materials on the homepage of the Institute of Physiology (physiology.aok.pte.hu).
- Notes
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practices 2, internet study material, printable notebook, 2016
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practice Worksheets 2, internet study material, printable notebook,
2016
- Recommended literature
L.S. Costanzo: Physiology, 5th edition, 2014
W.F. Ganong: Review of Medical Physiology, 2012, Appleton and Lange, Lange Medical Publications
Fonyó: Principles of Medical Physiology, Medicina Publishing, 2002
J.B. West (ed.): Best and Taylor’s Physiological Basis of Medical Practice, Williams and Wilkins, 1998
Lectures
1 Endocrinology of the adrenal cortex. I.
Dr. László Kristóf
2 Endocrinology of the adrenal cortex. II.
Dr. László Kristóf
3 The adrenal medulla. Endocrinology of stress
Dr. László Kristóf
4 Hormonal control of calcium homeostasis
Dr. Lengyel Ferenc
5 The endocrine pancreas
Dr. Zelena Dóra
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6 Hormonal control of intermediary metabolism.
Dr. Zelena Dóra
7 Special problems of neonatal physiology. Physiology of ageing
Dr. Lengyel Ferenc
8 Ionic mechanism of membrane potential. Action potential and its propagation.
Dr. Buzás Péter
9 Electrophysiology of synapses. Neurochemical basis of neurotransmission. Function of the neuromuscular junction.
Dr. Buzás Péter
10 Molecular mechanism of muscle contraction. Mechanics, energetics and heat production of muscle contraction.
Dr. Környei József László
11 Electric characteristics of muscle contraction, muscle tone, fatigue. Contraction of smooth muscle.
Dr. Környei József László
12 The motor unit. Peripheral neural mechanism of muscle control.
Dr. Buzásné Dr. Telkes Ildikó
13 Functional importance of mechanoreceptors
Dr. Buzás Péter
14 General properties of spinal cord reflexes. Integrative functions of the spinal cord.
Dr. Buzásné Dr. Telkes Ildikó
15 The spinal shock. Decerebrate rigidity.
Péczely László Zoltán
16 Postural coordination, Locomotion.
Péczely László Zoltán
17 Extrapyramidal system.
Kertes Erika
18 Physiology of the vestibular system.
Dr. Ollmann Tamás
19 Cerebellar control of motor functions.
Dr. Ollmann Tamás
20 Cortical control of motor functions. The pyramidal system.
Dr. Hernádi István
21 Somaesthetic mechanisms. Somatotopic representations in the sensory systems.
Dr. Buzás Péter
22 Thalamocortical somatosensory functions. The sensory cortex.
Dr. Buzás Péter
23 Pain mechanism. Opiate recptors.
Dr. Buzás Péter
24 Optics of vision, refractory errors of the eye. Retinal mechanisms.
Dr. Nemes Vanda
25 Visual pathways, midbrain mechanism of vision. Central mechanism of vision.
Dr. Nemes Vanda
26 Eye movements and their control.
Dr. Nemes Vanda
27 Physiology of hearing. Central auditory mechanisms.
Dr. Buzásné Dr. Telkes Ildikó
28 The chemical senses. Olfaction. Taste.
Dr. Szabó István
29 The autonomic nervous system.
Dr. Környei József László
30 Electroencephalography. Clinical importance of the evoked potential technique.
Dr. László Kristóf
31 Neural control mechanism of sleep. Control of biological rhythms.
Dr. László Kristóf
32 The diencephalon (hypothalamus). Its motor, autonomic and hormonal regulatory functions.
Dr. Ollmann Tamás
33 The concept of drive and motivation. The limbic system.
Dr. László Kristóf
34 Homeostatic drives. Central neural regulation of hunger and thirst.
Dr. Szabó István
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35 Monoaminergic systems and their functions. I.
Péczely László Zoltán
36 Monoaminergic systems and their functions. II.
Péczely László Zoltán
37 Emotions and their central nervous mechanism.
Dr. Ollmann Tamás
38 Mechanism of learning.
Péczely László Zoltán
39 Types and disorders of memory functions.
Péczely László Zoltán
40 Plasticity of the peripheral and central nervous system.
Dr. Varga Csaba
41 Functions of the frontal lobe. The parieto-temporal lobe.
Dr. László Kristóf
42 Cerebral hemisphere dominance. Neurophysiological mechanisms of speech. Speech disorders.
Dr. László Kristóf
Practices
Seminars
Exam topics/questions
The criterion of admission to the exam is the successful completion of the practice carried out in paralell (midsemester grade with the result different from ?failed?).
Topics of questions for the theoretical examination
1. Describe the body fluid compartments and explain the methods used for measurement of body fluid volumes
2. Describe the major plasma proteins and the other non-electrolytic constituents of blood and explain their function in the body
3. Describe the intra- and extracellular ionic components and explain their physiological functions
4. The structure, function and origin of erythrocytes
5. Characterize the various leukocytes indicating their origins and functions
6. Origin and function of blood platelets
7. The basic structure and metabolism of haemoglobin and the metabolism of iron
8. Describe the two pathways involved in the initiation of blood coagulation
9. Specific mechanism of clot formation
10. Describe the mechanism of fibrinolysis. Explain the significance of anticlotting mechanism
11. Regulation of H+ ion concentration in the blood
12. A-B-0 blood groups. The Rh blood types
13. The role of leukocytes in the defence mechanism
14. Mechanical activity of the heart and the three-component model of heart muscle. Calcium ion movements within the cardiac muscle cell
15. Generators and conductors of impulses in the heart. Refractory periods
16. The sequence of events in the cardiac cycle
17. The human electrocardiogram (ECG). Electrocardiography: bipolar and unipolar leads
18. The heart sounds. Phonocardiography (PCG)
19. Cardiac output: measurement, normal standards and physiological variations
20. Metabolism and energetics of cardiac muscle
21. Ventricular wall tension and the Laplace relationship
22. The heart-lung preparation (Starling’s laws)
23. Arterial blood pressure: determinants of normal arterial blood pressure
24. The arterial and the venous pulse. Basic principles of hemodynamics.
25. Circulation through the capillaries
26. The properties, production and the movement of lymph
27. Circulation in the vein. Effect of gravity on circulation
28. The pulmonary circulation. Control of lung vessels
29. The coronary circulation
30. Cerebral circulation. The concept of blood-brain barrier
31. Splanchnic circulation
32. Skeletal muscle circulation. Cutaneous circulation
33. Nervous control of the heart
34. Control mechanisms of the circulatory system: general considerations
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35. Local control of the vascular smooth muscle
36. Autoregulation of blood flow in tissues and organs
37. The function and importance of baroreceptors in the regulation of circulation
38. Reflex control mechanisms of circulation
39. Mechanisms of vasoconstriction and vasodilatation
40. Mechanics of respiration (functions of respiratory muscles, compliance, intrathoracic pressures, respiratory volumes)
41. Alveolar air, alveolar ventilation, dead spaces. Function of the respiratory passageways
42. Gaseous exchange in the lungs and tissues
43. O2 and CO2 transport in the body
44. Peripheral and central regulatory mechanisms of respiration. Respiratory reflexes
45. Chemical control of respiration. Acidosis, alkalosis
46. Different types of hypoxia. Oxygen treatment. Mechanisms of acclimatisation. Nitrogen narcosis. Decompression sickness
47. Describe the origin, composition, function and control of salivary secretion
48. Describe the origin, nature and function of gastric secretion indicating the mechanisms of regulation
49. Mechanism and regulation of gastrointestinal movements
50. Identify the pancreatic secretions, their components, their action and the substrates on which they act. Control mechanism of pancreatic secretion
51. Describe the basic ingredients and functions of the bile indicating the origin and fate of the components and the factors controlling bile secretions and gall bladder functions
52. Identify the components and functions of the intestinal system
53. Describe how carbohydrate is digested and absorbed indicating the enzymes involved
54. Describe how fat is digested and absorbed indicating the enzymes and secretions involved
55. Describe how protein is digested and absorbed indicating the enzymes and secretions involved
56. Dynamics of glomerular filtration. Glomerular filtration rate. Plasma clearance
57. Renal blood flow. Clearance of PAH. Extraction ratio. Filtration fraction
58. Regulation of renal blood flow and pressure. Renin-angiotensin system
59. Reabsorption and secretion of different substances in the renal tubule. Methods for their investigation
60. Concentrating and diluting mechanisms of the kidney
61. Fluid volume regulation of the body
62. Regulation of concentrations of ions in the extracellular fluid. Regulation of osmolality of body fluids
63. Basal metabolic rate. Describe factors influencing the basal metabolism
64. Define metabolic rate explaining those factors influencing the total expenditure of energy by the body
65. Describe the necessary elements of normal diet
66. The normal body temperature and its physiological variations. Hyperthermia, fever, hypothermia
67. Chemical regulation of body temperature, changes of regulation at low and high environmental temperature
68. Physical regulation of body temperature, changes of regulation at low and high environmental temperature
69. Central regulatory mechanisms of heat production and heat loss
70. Mechanisms of hormone action (receptors, intracellular mediators, cAMP, Ca2+ and diacylglycerol, protein kinases)
71. Mechanism of hormonal regulation. Negative and positive feedback controls in the endocrine system
72. The anterior pituitary hormones. Regulation of pituitary hormone secretions. Pituitary dysfunction
73. Function of growth hormone during development and after adolescence
74. Abnormalities of thyroid secretion. Goitrogens
75. Function of the thyroid gland. Iodine metabolism in the body
76. Hormonal changes during menstrual cycle
77. Hormonal changes during pregnancy. Role of placenta in pregnancy. Foeto-placental unit
78. Hormones of lactation
79. Mechanism of erection and ejaculation. The sexual act (coitus)
80. The function of testis, epididymis, seminal vesicle and prostate
81. Regulation of the sexual behaviour. Maternal behaviour
82. Physiological changes at puberty and climacteric
83. Vasopressin and oxytocin. Function of ANH (atrionatriuretic hormone)
84. The effects of prostaglandins
85. The endocrine pancreas
86. Function of insulin in the body. Diabetes mellitus
87. Hormonal control of carbohydrate metabolism
88. Hormonal control of calcium and phosphor homeostasis
89. Hormonal function of the adrenocortical system. Hypophyseal regulation of the adrenocortical system. Stress and the adaptation syndrome
90. Function and regulation of mineralocorticoids
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91. Function and regulation of glucocorticoids
92. Consequences of hypo- and hyperfunction of the adrenal cortex. Androgens and oestrogens of the adrenal cortex.
93. Hormones of the adrenal medulla. Importance of the sympathoadrenal system
94. Physiology of ontogenesis and ageing.
95. Molecular mechanism of muscle contraction. The regulatory role of calcium ion
96. Mechanical characteristics of muscle. Differentiation of fast and slow twitch muscle fibres. Role of the connective tissue in the function of muscles
97. Mechanism of fatigue
98. Electromyography (EMG)
99. The source of energy for muscle contraction (aerobe and anaerobe processes). Heat production during contraction-relaxation cycle
100. The neuromuscular junction
101. Structural and functional differences between skeletal and smooth muscles. Mechanism of smooth muscle contraction
102. Membrane potential and action potential: explain their ionic mechanisms. Membrane properties of CNS neurons
103. The compound action potential. Conductive properties of various nerve fibres
104. Neurochemistry of synapses, neurotransmitters, postsynaptic receptors and neuromodulators. EPSP, IPSP
105. The myotatic (stretch) reflex. Gamma motoneurons
106. The motor units. Central control of muscle contractions
107. Types of mechanoreceptors and their role in motor control
108. How do cutaneous mechanoreceptors help to explore, learn and know our environment?
109. Somatosensory mechanisms of spinal cord and brain stem
110. Pain mechanisms, central and peripheral components
111. Descendent control (gating) of nociception and of pain reactions
112. Organisation of primary somatosensory cortex, thalamocortical projection and somatotopy
113. The human electroencephalogram (EEG). Evoked potential (EP) technique
114. Neural mechanisms of sleep and correlated somatic, autonomic and bioelectrical phenomena. The role of reticular formation in the
sleep-wakefulness cycle
115. The diencephalon (hypothalamus), its motor, autonomic and hormonal regulatory function
116. Hunger and thirst. Central regulatory processes of food and water intake
117. Central mechanisms of locomotion
118. Decerebration rigidity and spinal shock (symptoms and mechanisms)
119. Postural and righting reflexes, their central mechanisms and localisation within the spinal cord, brain stem and neocortex
120. Structure and function of the extrapyramidal system
121. Symptoms after damages of different extrapyramidal structures. Role of neurotransmitters in the extrapyramidal functions
122. Importance of the cerebellum in co-ordination of movements
123. Cerebellar cortical mechanisms
124. Structure and function of the vestibular system
125. Functions of the autonomic nervous system. Autonomic reflexes
126. Humoral mediators in the autonomic nervous system. Adrenergic, cholinergic and opioid receptors
127. Structures, connections and functions of the limbic system
128. Functions of the motor cortex. Symptoms following its damage
129. Corticospinal (pyramidal) system. Consequences of lesions of the pyramidal pathways and the peripheral motoneuron
130. The concept of drive and motivation. Their integrated neural mechanisms. Reticular activating system
131. Emotions and their central nervous mechanisms
132. The phenomena of operant (instrumental) and classical (Pavlovian) conditioning. Mechanism of reinforcement
133. Electrical and chemical self-stimulation. Rewarding (positive) and punishing (negative) reinforcement. Simple learning processes. Exceptional forms of conditioning
134. Types and disorders of memory functions
135. Cerebral dominance. Lateralisation of functions in the hemispheres. Split-brain examinations
136. Functions of the parietal and temporal association (intrinsic) areas of the neocortex. Symptoms after damages (apraxia, agnosia)
137. Neurophysiological mechanisms of speech. Speech disorders
138. Functions of the frontal lobe (prefrontal intrinsic area)
139. Functions of the temporal lobe (Kluver-Bucy syndrome)
140. Central monoaminergic systems and their functional significance
141. Peripheral auditory mechanisms (conductive apparatus and cochlea)
142. Central auditory pathways, acoustic cortex and related mechanisms
143. Physiological optics
144. The retina. Photoreceptors and neuronal functions in the retina
145. Central visual pathways, the visual cortex and their functions
146. Colour vision. Stereoscopic vision
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147. Peripheral and central mechanisms of olfaction
148. Peripheral and central mechanisms of sensation of taste
149. Plasticity in the nervous system. Consequences of sensory deprivation in the visual cortex. Ageing. Transplantation
Questions for the student lab report:
1. Examination of oestrus cycle in rat
2. Different tests of pregnancy
3. Determination of human blood glucose level
4. Direct and indirect stimulation of nerve-muscle preparation;
5. Recording of a twitch contraction; Effects of repetitive stimulation muscles (complete and incomplete tetanus)
6. Effect of load on muscular contraction
7. Examination of fatigue in nerve-muscle preparation and on humans
8. Electromyographic registration methods (EMG)
9. Measurement of conduction velocity
10. Recording of a compound action potential of peripheral nerve trunks
11. The law of polar excitation
12. Demonstration of the Pflüger’s law
13. Measurement of rheobase and chronaxy
14. Effect of narcosis on peripheral nerves
15. Examination of reflexes in a frog (intact and spinal animal)
16. Examination of reflexes in the human
17. Stereotaxic technique
18. Reflex time, reaction time and action time
19. Electroencephalogram (EEG)
20. Measurement of visual acuity
21. Refractive errors and their corrections
22. Measurement of astigmia
23. Examination of pupil reactions
24. Perimetry
25. Examination of colour weakness and colour blindness
26. Audiometry
Study material for the final exam is the sum total of information covered in the obligatory textbook, on the homepage of the Institute, as well as knowledge given at the lectures and lab practices.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPO-H2G-T HUMAN PHYSIOLOGY 2 - PRACTICE
Course director: DR. ZOLTÁN KARÁDI, professor
Institute of Physiology
2 credit ▪ midsemester grade ▪ Med.-biol. theoretical module and practical skills subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 5 – not limited Prerequisites: OPO-H1E-T completed
Topic
The most important mission of the Physiology Course in medical education is to familiarize students with the attributes of healthy functions of the living organism.
While acquiring knowledge about the most important functional characteristics of the human body the students can rely on their prior
studies in biology, biophysics, chemistry-biochemistry and anatomy.
During the semester we introduce the most important elements of functioning of the organs and organ systems, as well as their cooperation also required to adapting to the environment, and the factors affecting these processes.
Special emphasis is placed on the neural and humoral regulatory processes of these life-functions, which are vital to maintain and preserve the homeostasis of the organism.
With the transfer of all this knowledge we would like to mould a holistic attitude and thinking of students, which will enable them to better understand the functions of the now healthy, however, later dysfunctional human organism.
Conditions for acceptance of the semester
Maximum of 15 % absence allowed
Mid-term exams
Written test on the 11th week Friday at 16:00.
Making up for missed classes
The missed lab practice is advised to be covered by joining another group while the same topic is on schedule.
Reading material
- Obligatory literature
J.E. Hall: Guyton and Hall Textbook of Medical Physiology, 12th edition, 2013
- Literature developed by the Department
Figures of the lectures given are available on the homepage of Institute of Physiology and on the Neptun Meet Street.
Important messages on new information will be announced at the lectures and will be sent to you by course mails.
Please always find the current updated information and study materials on the homepage of the Institute of Physiology (physiology.aok.pte.hu).
- Notes
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practices 2, internet study material, printable notebook, 2016
Homepage of PTE ÁOK Institute of Physiology: Physiology Lab Practice Worksheets 2, internet study material, printable notebook,
2016
- Recommended literature
L.S. Costanzo: Physiology, 5th edition, 2014
W.F. Ganong: Review of Medical Physiology, 2012, Appleton and Lange, Lange Medical Publications
Fonyó: Principles of Medical Physiology, Medicina Publishing, 2002
J.B. West (ed.): Best and Taylor’s Physiological Basis of Medical Practice, Williams and Wilkins, 1998
Lectures
Practices
1 The endocrine pancreas.
2 The endocrine pancreas.
3 Reproduction.
4 Reproduction.
5 Peripheral nervous system I.
6 Peripheral nervous system I.
7 Peripheral nervous system II.
8 Peripheral nervous system II.
9 Seminar: Endocrinology, Peripheral nerve, Membrane potential, Action potential, Synaptic transmission.
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10 Student report (test).
11 Experiments on muscles.
12 Experiments on muscles.
13 Electromyography, Examination of fatigue.
14 Electromyography, Examination of fatigue.
15 Examination of reflexes.
16 Examination of reflexes.
17 Central nervous system.
18 Central nervous system.
19 Seminar: Muscle and reflexes.
20 Student report (test).
21 Sensory organs I.
22 Sensory organs I.
23 Sensory organs II.
24 Sensory organs II.
25 Electroencephalography in humans.
26 Electroencephalography in humans.
27 Student lab report.
28 Student lab report.
Seminars
Exam topics/questions
Topics of questions for the theoretical examination
1. Describe the body fluid compartments and explain the methods used for measurement of body fluid volumes
2. Describe the major plasma proteins and the other non-electrolytic constituents of blood and explain their function in the body
3. Describe the intra- and extracellular ionic components and explain their physiological functions
4. The structure, function and origin of erythrocytes
5. Characterize the various leukocytes indicating their origins and functions
6. Origin and function of blood platelets
7. The basic structure and metabolism of haemoglobin and the metabolism of iron
8. Describe the two pathways involved in the initiation of blood coagulation
9. Specific mechanism of clot formation
10. Describe the mechanism of fibrinolysis. Explain the significance of anticlotting mechanism
11. Regulation of H+ ion concentration in the blood
12. A-B-0 blood groups. The Rh blood types
13. The role of leukocytes in the defence mechanism
14. Mechanical activity of the heart and the three-component model of heart muscle. Calcium ion movements within the cardiac muscle cell
15. Generators and conductors of impulses in the heart. Refractory periods
16. The sequence of events in the cardiac cycle
17. The human electrocardiogram (ECG). Electrocardiography: bipolar and unipolar leads
18. The heart sounds. Phonocardiography (PCG)
19. Cardiac output: measurement, normal standards and physiological variations
20. Metabolism and energetics of cardiac muscle
21. Ventricular wall tension and the Laplace relationship
22. The heart-lung preparation (Starling’s laws)
23. Arterial blood pressure: determinants of normal arterial blood pressure
24. The arterial and the venous pulse. Basic principles of hemodynamics.
25. Circulation through the capillaries
26. The properties, production and the movement of lymph
27. Circulation in the vein. Effect of gravity on circulation
28. The pulmonary circulation. Control of lung vessels
29. The coronary circulation
30. Cerebral circulation. The concept of blood-brain barrier
31. Splanchnic circulation
32. Skeletal muscle circulation. Cutaneous circulation
33. Nervous control of the heart
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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34. Control mechanisms of the circulatory system: general considerations
35. Local control of the vascular smooth muscle
36. Autoregulation of blood flow in tissues and organs
37. The function and importance of baroreceptors in the regulation of circulation
38. Reflex control mechanisms of circulation
39. Mechanisms of vasoconstriction and vasodilatation
40. Mechanics of respiration (functions of respiratory muscles, compliance, intrathoracic pressures, respiratory volumes)
41. Alveolar air, alveolar ventilation, dead spaces. Function of the respiratory passageways
42. Gaseous exchange in the lungs and tissues
43. O2 and CO2 transport in the body
44. Peripheral and central regulatory mechanisms of respiration. Respiratory reflexes
45. Chemical control of respiration. Acidosis, alkalosis
46. Different types of hypoxia. Oxygen treatment. Mechanisms of acclimatisation. Nitrogen narcosis. Decompression sickness
47. Describe the origin, composition, function and control of salivary secretion
48. Describe the origin, nature and function of gastric secretion indicating the mechanisms of regulation
49. Mechanism and regulation of gastrointestinal movements
50. Identify the pancreatic secretions, their components, their action and the substrates on which they act. Control mechanism of pancreatic secretion
51. Describe the basic ingredients and functions of the bile indicating the origin and fate of the components and the factors controlling bile secretions and gall bladder functions
52. Identify the components and functions of the intestinal system
53. Describe how carbohydrate is digested and absorbed indicating the enzymes involved
54. Describe how fat is digested and absorbed indicating the enzymes and secretions involved
55. Describe how protein is digested and absorbed indicating the enzymes and secretions involved
56. Dynamics of glomerular filtration. Glomerular filtration rate. Plasma clearance
57. Renal blood flow. Clearance of PAH. Extraction ratio. Filtration fraction
58. Regulation of renal blood flow and pressure. Renin-angiotensin system
59. Reabsorption and secretion of different substances in the renal tubule. Methods for their investigation
60. Concentrating and diluting mechanisms of the kidney
61. Fluid volume regulation of the body
62. Regulation of concentrations of ions in the extracellular fluid. Regulation of osmolality of body fluids
63. Basal metabolic rate. Describe factors influencing the basal metabolism
64. Define metabolic rate explaining those factors influencing the total expenditure of energy by the body
65. Describe the necessary elements of normal diet
66. The normal body temperature and its physiological variations. Hyperthermia, fever, hypothermia
67. Chemical regulation of body temperature, changes of regulation at low and high environmental temperature
68. Physical regulation of body temperature, changes of regulation at low and high environmental temperature
69. Central regulatory mechanisms of heat production and heat loss
70. Mechanisms of hormone action (receptors, intracellular mediators, cAMP, Ca2+ and diacylglycerol, protein kinases)
71. Mechanism of hormonal regulation. Negative and positive feedback controls in the endocrine system
72. The anterior pituitary hormones. Regulation of pituitary hormone secretions. Pituitary dysfunction
73. Function of growth hormone during development and after adolescence
74. Abnormalities of thyroid secretion. Goitrogens
75. Function of the thyroid gland. Iodine metabolism in the body
76. Hormonal changes during menstrual cycle
77. Hormonal changes during pregnancy. Role of placenta in pregnancy. Foeto-placental unit
78. Hormones of lactation
79. Mechanism of erection and ejaculation. The sexual act (coitus)
80. The function of testis, epididymis, seminal vesicle and prostate
81. Regulation of the sexual behaviour. Maternal behaviour
82. Physiological changes at puberty and climacteric
83. Vasopressin and oxytocin. Function of ANH (atrionatriuretic hormone)
84. The effects of prostaglandins
85. The endocrine pancreas
86. Function of insulin in the body. Diabetes mellitus
87. Hormonal control of carbohydrate metabolism
88. Hormonal control of calcium and phosphor homeostasis
89. Hormonal function of the adrenocortical system. Hypophyseal regulation of the adrenocortical system. Stress and the adaptation syndrome
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90. Function and regulation of mineralocorticoids
91. Function and regulation of glucocorticoids
92. Consequences of hypo- and hyperfunction of the adrenal cortex. Androgens and oestrogens of the adrenal cortex.
93. Hormones of the adrenal medulla. Importance of the sympathoadrenal system
94. Physiology of ontogenesis and ageing.
95. Molecular mechanism of muscle contraction. The regulatory role of calcium ion
96. Mechanical characteristics of muscle. Differentiation of fast and slow twitch muscle fibres. Role of the connective tissue in the function of muscles
97. Mechanism of fatigue
98. Electromyography (EMG)
99. The source of energy for muscle contraction (aerobe and anaerobe processes). Heat production during contraction-relaxation cycle
100. The neuromuscular junction
101. Structural and functional differences between skeletal and smooth muscles. Mechanism of smooth muscle contraction
102. Membrane potential and action potential: explain their ionic mechanisms. Membrane properties of CNS neurons
103. The compound action potential. Conductive properties of various nerve fibres
104. Neurochemistry of synapses, neurotransmitters, postsynaptic receptors and neuromodulators. EPSP, IPSP
105. The myotatic (stretch) reflex. Gamma motoneurons
106. The motor units. Central control of muscle contractions
107. Types of mechanoreceptors and their role in motor control
108. How do cutaneous mechanoreceptors help to explore, learn and know our environment?
109. Somatosensory mechanisms of spinal cord and brain stem
110. Pain mechanisms, central and peripheral components
111. Descendent control (gating) of nociception and of pain reactions
112. Organisation of primary somatosensory cortex, thalamocortical projection and somatotopy
113. The human electroencephalogram (EEG). Evoked potential (EP) technique
114. Neural mechanisms of sleep and correlated somatic, autonomic and bioelectrical phenomena. The role of reticular formation in the sleep-wakefulness cycle
115. The diencephalon (hypothalamus), its motor, autonomic and hormonal regulatory function
116. Hunger and thirst. Central regulatory processes of food and water intake
117. Central mechanisms of locomotion
118. Decerebration rigidity and spinal shock (symptoms and mechanisms)
119. Postural and righting reflexes, their central mechanisms and localisation within the spinal cord, brain stem and neocortex
120. Structure and function of the extrapyramidal system
121. Symptoms after damages of different extrapyramidal structures. Role of neurotransmitters in the extrapyramidal functions
122. Importance of the cerebellum in co-ordination of movements
123. Cerebellar cortical mechanisms
124. Structure and function of the vestibular system
125. Functions of the autonomic nervous system. Autonomic reflexes
126. Humoral mediators in the autonomic nervous system. Adrenergic, cholinergic and opioid receptors
127. Structures, connections and functions of the limbic system
128. Functions of the motor cortex. Symptoms following its damage
129. Corticospinal (pyramidal) system. Consequences of lesions of the pyramidal pathways and the peripheral motoneuron
130. The concept of drive and motivation. Their integrated neural mechanisms. Reticular activating system
131. Emotions and their central nervous mechanisms
132. The phenomena of operant (instrumental) and classical (Pavlovian) conditioning. Mechanism of reinforcement
133. Electrical and chemical self-stimulation. Rewarding (positive) and punishing (negative) reinforcement. Simple learning processes. Exceptional forms of conditioning
134. Types and disorders of memory functions
135. Cerebral dominance. Lateralisation of functions in the hemispheres. Split-brain examinations
136. Functions of the parietal and temporal association (intrinsic) areas of the neocortex. Symptoms after damages (apraxia, agnosia)
137. Neurophysiological mechanisms of speech. Speech disorders
138. Functions of the frontal lobe (prefrontal intrinsic area)
139. Functions of the temporal lobe (Kluver-Bucy syndrome)
140. Central monoaminergic systems and their functional significance
141. Peripheral auditory mechanisms (conductive apparatus and cochlea)
142. Central auditory pathways, acoustic cortex and related mechanisms
143. Physiological optics
144. The retina. Photoreceptors and neuronal functions in the retina
145. Central visual pathways, the visual cortex and their functions
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146. Colour vision. Stereoscopic vision
147. Peripheral and central mechanisms of olfaction
148. Peripheral and central mechanisms of sensation of taste
149. Plasticity in the nervous system. Consequences of sensory deprivation in the visual cortex. Ageing. Transplantation
Questions for the student lab report:
1. Examination of oestrus cycle in rat
2. Different tests of pregnancy
3. Determination of human blood glucose level
4. Direct and indirect stimulation of nerve-muscle preparation;
5. Recording of a twitch contraction; Effects of repetitive stimulation muscles (complete and incomplete tetanus)
6. Effect of load on muscular contraction
7. Examination of fatigue in nerve-muscle preparation and on humans
8. Electromyographic registration methods (EMG)
9. Measurement of conduction velocity
10. Recording of a compound action potential of peripheral nerve trunks
11. The law of polar excitation
12. Demonstration of the Pflüger’s law
13. Measurement of rheobase and chronaxy
14. Effect of narcosis on peripheral nerves
15. Examination of reflexes in a frog (intact and spinal animal)
16. Examination of reflexes in the human
17. Stereotaxic technique
18. Reflex time, reaction time and action time
19. Electroencephalogram (EEG)
20. Measurement of visual acuity
21. Refractive errors and their corrections
22. Measurement of astigmia
23. Examination of pupil reactions
24. Perimetry
25. Examination of colour weakness and colour blindness
26. Audiometry
Study material for the final exam is the sum total of information covered in the obligatory textbook, on the homepage of the Institute, as well as knowledge given at the lectures and lab practices.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Lengyel Ferenc (LEFAAA.T.JPTE), Kovács Anita (KOAMAET.PTE)
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ATT4-T PHYSICAL EDUCATION 4
Course director: TAMÁS TÉCZELY, physical education teacher
UP MS Sports Facilities
0 credit ▪ signature ▪ Criterion requirement subject ▪ both semesters semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 28 practices + 0 seminars = total of 28 hours
Course headcount limitations (min.-max.): 2 – 50 Prerequisites: ATT3-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test: 1
Topic
This subject provides theoretical and practical information for the students to maintain and improve their physical condition and helps to
deepen the knowledge in the field of healthy lifestyle.
Theoretical and practical knowledge during different types of exercises e.g. how to improve endurance, muscle force, motor skills and
how to prevent the body from injuries.
Conditions for acceptance of the semester
Active participation at least 20 practical lessons provided by the Institute of Human Movement Sciences or regular participation of the
trainings of the Medikus Sport Club or PEAC.
Mid-term exams
-
Making up for missed classes
We provide opportunities to attend extra lessons in the first week of the exam period in that case the requirements are not fulfilled till the
end of the teaching weeks with agreement of the PE Teacher.
Reading material
- Obligatory literature
- Literature developed by the Department
Not available.
- Notes
- Recommended literature
Lectures
Practices
1-28 For the list of actual courses please turn to the end of this document
Seminars
Exam topics/questions
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Farkas György (FAGMAAO.PTE), Lipcsik Zoltán (LIZIAAT.PTE), Németh Attila Miklós (NEAGAET.PTE), Téczely Tamás
(PETLAAT.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPR-HUF-O-T FINAL EXAMINATION IN HUNGARIAN PHARMACEUTICAL TERMINOLOGY - ORAL
Course director: DR. GÁBOR RÉBÉK-NAGY, associate professor
Department of Languages for Specific Purposes
0 credit ▪ signature ▪ Criterion requirement subject ▪ both semesters semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 0 practices + 0 seminars = total of 0 hours
Course headcount limitations (min.-max.): 1 – 400 Prerequisites: none
Topic
Exam of Pharmaceutical Hungarian language skills required for the pharmaceutical practice.
Conditions for acceptance of the semester
-
Mid-term exams
-
Making up for missed classes
-
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
-
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
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OPR-HUF-W-T FINAL EXAMINATION IN HUNGARIAN PHARMACEUTICAL TERMINOLOGY - WRITTEN
Course director: DR. GÁBOR RÉBÉK-NAGY, associate professor
Department of Languages for Specific Purposes
0 credit ▪ signature ▪ Criterion requirement subject ▪ both semesters semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 0 practices + 0 seminars = total of 0 hours
Course headcount limitations (min.-max.): 1 – 400 Prerequisites: none
Topic
Exam of Pharmaceutical Hungarian language skills required for the pharmaceutical practice.
Conditions for acceptance of the semester
-
Mid-term exams
-
Making up for missed classes
-
Reading material
- Obligatory literature
- Literature developed by the Department
- Notes
- Recommended literature
Lectures
Practices
Seminars
Exam topics/questions
-
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
61
OPR-SG1-T PROFESSIONAL PRACTICE 1
Course director: DR. ANDRÁS TAMÁS FITTLER, associate professor
Department of Pharmaceutics and University Pharmacy
0 credit ▪ signature ▪ Criterion requirement subject ▪ spring semester ▪ recommended semester: 4
Number of hours/semester: 0 lectures + 160 practices + 0 seminars = total of 160 hours
Course headcount limitations (min.-max.): 1 – 70 Prerequisites: OPG-GI1-T parallel + OPG-GPR-T completed
The subject can only be registered in case of a PASSED and valid health aptitude test!
Topic
After the 4. semester the students should complete a summer professional practice in a community pharmacy and hospital pharmacy
(host institution) to acquire the basic knowledge regarding the pharmaceutical supply and care in these settings. After the completion of
the professional practice the student will be able to recall the personal and objective criteria, the operation and procedures of the
community or hospital pharmacy.
Furthermore the professional practice can be completed in a pharmaceutical company, pharmaceutical wholesaler or foreign (non
Hungarian) units equivalent to these. To fulfill the professional practice in abroad the student should submit a written request to the
course director until the deadline of the application for professional practice. In case of spending the professional practice abroad it is advisable for the students to spend 2 weeks in a Hungarian pharmacy to earn experiences regarding the Hungarian pharmacies.
It is possible to complete the 4 weeks of the professional practice in two practice sites in consecutive 2-2 weeks. The application form, syllabus and certificate of the completion of the professional practice are available from the website of the Registrar’s Office.
The accreditation of the professional practice site (pharmacy) is advisable but not a mandatory requirement for professional practice 1. and 2.
Conditions for acceptance of the semester
Before starting the professional practice student should have a semester acceptance of Basic Principles of Pharmacy. Student should
transmit the attendance sheet, record of practice and the completion of the professional practice to the acceptance of the professional
practice. At the end of the professional practice the supervisor pharmacist or the deputy pharmacist evaluates the performance of the
student in a three-grade evaluation with written summary.
The student is responsible to fulfill the administrative criteria set by the Registrar’s Office.
Mid-term exams
The duration of the professional practice is 4 weeks, 8 hours daily, of which 2 hours may be spent on individual preparation and study.
During the professional practice attendance should be recorded on an attendance sheet, which is available from the website of the
Registrar’s Office. The requirement regarding the opening hours of the pharmacy is 8 hours daily. The student should work under the
supervision of the supervisor pharmacist or the deputy pharmacist during the whole practice and preparing a record daily of his or her
work.
The organization and reconciliation of the place and time of the professional practice is the responsibility of the student. Before starting
the professional practice the student should fill the acceptance letter for professional practice form and collect signatures of supervisor
pharmacist and the leader or head of the professional practice site (pharmacy, company) and pass to the Registrar’s Office until the last
day of April.
Making up for missed classes
The absence during the professional practice should be covered with a certificate (e.g.: in case of illness) to the supervisor pharmacist
and course director and should make up during the period of the professional practice. In case of health problems the professional practice
can be divided into 2-2 weeks.
Reading material
- Obligatory literature
White coat, Protective shoes
- Literature developed by the Department
- Notes
Pharmaceutical Propedeutic, Basic Principles of Pharmacy,
- Recommended literature
European Pharmacopoeia
Pharmacopoeia Hungarica
Hungarian National Formulary: Formulae Normales VII (FoNo VII)
Compendium
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
62
Lectures
Practices
1-160 COMMUNITY PHARMACY
The role of professionals working in the pharmacy.
The premises and objective criteria of the pharmacy.
Knowledge and skills regarding the storage and inventory: temperature and environment, strength and cross signs
Handling weighs, pharmacy tools and machines.
Getting familiar with the chemical substances and herbs.
Packaging and labelling.
Basic skills of pharmaceutical technology (measurement, sifting, mixing of powders, dilution, calculation of solution concentration, calculation of doses).
Getting to know workflows and occupational safety regulations
Getting to know pharmaceutical manuals and professional journals
PHARMACEUTICAL COMPANY
The role of pharmaceutical company in the drug supply chain.
The organogram and key personnel of pharmaceutical company
The Good Manufacturing Practice (GMP): regulations and application
Participating in the manufacturing process
Getting familiar with the operation and role of Quality Assurance and Quality Control
The role of microbiology in the pharmaceutical company
Special operation characteristics of a pharmaceutical company
HOSP-ITAL - CLINICAL PHARMACY
The specialties of the hospital pharmacy compounding
Sterile and non-sterile medium-sized pharmacy compounding, individualized formulas
Pharmaceutical informatics in the hospital and hospital pharmacy
Financing of the hospital care and drug expenditures
Ordering, procurement and stockpiling of medicines in hospital pharmacy and wards. Medication management
Therapeutic consultation
Getting familiar with the operation and role of Quality Assurance and Quality Control.
Communication with patients and professionals in hospital pharmacy setting
Seminars
Exam topics/questions
The record of the practice is accepted by the course director. The record should include the topics listed in the syllabus and the completion
of 2 related professional problems described in minimum 400 words of each. After the completion of the professional practice the student can evaluate the professional practice site and the supervisor pharmacist.
Information – The following skills of the Booklet for Clinical Skills shall be accomplished in the framework of the subject
Participants
Dr. Fittler András Tamás (FIAQAAK.PTE), Dr. Mayer Klára (MAKMABO.PTE), Dr. Pál Szilárd (PASMAAO.PTE)
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
63
ATT1-2-3-4-5 PHYSICAL EDUCATION COURSES 1-2-3-4-5
Sport day from to place min.
head-count
max. head-count
trainer
Aerobics Monday 18:00 19:00 SPO-SOR Sörház (Xavér str 19)
2 8 Dr. Szilárdné Kordély Erika
Aerobics Tuesday 19:00 20:00 SZEA-EDZ Main Building training room
2 8 Pajor Marietta
Aerobics Wednesday 18:00 19:00 SPO-SOR Sörház (Xavér str 19)
2 8 Dr. Szilárdné Kordély Erika
Aerobics Wednesday 19:00 20:00 SPO-SOR Sörház (Xavér str 19)
2 8 Pajor Marietta
Aerobics Thursday 18:00 19:00 SPO-SOR Sörház (Xavér str 19)
2 8 Dr. Szilárdné Kordély Erika
Athletics Monday 17:00 18:30 SPO-ATP PTE Athletics field (Ifjúság út 6.)
1 8 Hajduné Dr. László Zita
Athletics Wednesday 16:00 17:30 SPO-ATP PTE Athletics field (Ifjúság út 6.)
1 8 Hajduné Dr. László Zita
Badminton Thursday 16:30 17:45 SPO-TCS Sportshall - Jakabhegyi út 6.
2 7 Lipcsik Zoltán
Basketball (men) Thursday 22:00 23:30 SPO-TCS Sportshall - Jakabhegyi út 6.
4 20 Németh Attila Miklós
Basketball (women) Wednesday 18:00 19:30 SPO-TCS Sportshall - Jakabhegyi út 6.
2 6 Németh Attila Miklós
Body Slim Monday 19:00 20:00 SPO-MFK Mecsek Fitness Center (Ybl Miklós str. 10.)
2 7 Szőke Zita
Body Slim Thursday 20.30 21.30 SPO-FIT FITNEXX Premium (Jászai Mari u. 2,)
3 10 Solt Edit
Climbing Thursday 18:00 19:30 SPO-PSM "Pécsi Sasok" Sportscenter (Búza tér 6/b.)
2 6 Téczely Tamás
Cross Training Monday 20:30 22:00 SPO-CRF Cross Factory, Professor Gym yard (Megyeri út 4.)
1 6 Téczely Tamás
Dancing University Project - Bachata
Thursday 21:00 22:00 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Kovács Mónika
Dancing University Project - Ballroom Dancing
Tuesday 19.00 20:30 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Dr. Papp Judit
Dancing University Project - Ballroom Latin Dances
Tuesday 20:30 22:00 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Józsa János
Dancing University Project - Belly Dance
Thursday 18.00 19:30 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Indzsi Deniz
Dancing University Project - Body Shaping Dance Aerobics
Wednesday 17.30 19.00 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Szalai Kata
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
64
Sport day from to place min.
head-count
max. head-count
trainer
Dancing University Project - Breakness
Tuesday 16.00 17.30 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Filkóházi Zoltán
Dancing University Project - Croatian, Serbian and Macedonian Dances
Tuesday 17:30 19:00 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Vélin Veszna
Dancing University Project - Cuban Salsa
Thursday 19:30 21:00 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Vágási Barbara, Kutni Balázs
Dancing University Project - Hip-hop
Monday 18:30 20:00 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Horváth Tamás
Dancing University Project - Latin Freestyle Aerobics
Monday 17:00 18:30 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Buda Réka
Dancing University Project - Self-defense
Friday 13.00 14.30 SPO-I6T Dance Room (Ifjúság Street 6.)
1 4 Lenkei Zsolt
Elite Challenge Training Monday 18.00 19.30 Expo Center Pécs (Megyeri Road 72.)
4 Koltai Arnold
Elite Challenge Training Wednesday 18.00 19.30 Expo Center Pécs (Megyeri Road 72.)
4 Koltai Arnold
Elite Workout Monday 18.00 19.00 Expo Center Pécs (Megyeri Road 72.)
4 Koltai Arnold
Elite Workout Wednesday 18.00 19.00 Expo Center Pécs (Megyeri Road 72.)
4 Koltai Arnold
Football Friday 13:30 15:00 SPO-TCS Sportshall - Jakabhegyi út 6.
6 15 Téczely Tamás
Football Friday 15:00 16:30 SPO-TCS Sportshall - Jakabhegyi út 6.
6 15 Téczely Tamás
Handball (men) Wednesday 19:30 21:00 SPO-TCS Sportshall - Jakabhegyi út 6.
2 7 Lipcsik Zoltán
Handball (women) Monday 19.00 20.30 SPO-TCS Sportshall - Jakabhegyi út 6.
2 7 Lipcsik Zoltán
Hiking weekends Mecsek Hills 2 10 Farkas György
Horse Riding (six times) Sunday 9:00 13:00 „Apró Paták” Riding School- Siklós, Postaszállás utca 11.
1 2 Bohár Áron
Jogging Friday 17:00 18:30 SPO-JSK Jakabhegy street outdoor handball field
1 5 Dr. Karsai István
Kangoo Monday 19.00 20.30 SPO-SOR Sörház (Xavér str 19)
3 Téczely Tamás
Karate advanced Tuesday 20:00 21:30 SZEA-EDZ Main Building training room
2 7 József Kristóf
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
65
Sport day from to place min.
head-count
max. head-count
trainer
Karate advanced Thursday 20:00 21:30 SZEA-EDZ Main Building training room
2 7 József Kristóf
Kick-box Friday 19:00 20:30 SZEA-EDZ Main Building training room
2 12 Horváth László
Lacross Friday 19:00 20:30 SPO-V13 PTE Sports sites (Verseny u. 13.)
2 10 Dr. Rugási Endre
Nordic Walking Wednesday 17:30 19:00 SPO-ATP PTE Athletics field (Ifjúság út 6.)
1 8 Farkas György
Operational Medicine Training Program (functional skill development)
Tuesday 16:15 17:30 SZEA-EDZ Main Building training room
1 6 Lipcsik Zoltán
Shaolin Kung Fu Monday 19:00 20:30 SPO-EP8 Elementary School in 8 Építők Str.
1 4 Bornemissza Gergely
Squash Friday 16:30 18:00 SPO-SOR Sörház (Xavér str 19)
2 4 Téczely Tamás
Swimming Tuesday 12:00 13:30 SZEA-USZ Main Building swimming pool
1 4 Dr. Karsai István
Swimming Tuesday 17.00 18.30 PTE TTK uszoda Ifjúság út 6. 1 4 Kovács Zsófia
Swimming Wednesday 17.00 18.30 PTE TTK uszoda Ifjúság út 6. 1 4 Kovács Zsófia
Swimming Thursday 17.00 18..00 PTE TTK uszoda Ifjúság út 6. 1 6 Dr. Karsai István
Swimming Friday 13:30 15:00 SZEA-USZ Main Building swimming pool
3 15 Farkas György
Swimming Friday 15:00 16:00 SZEA-USZ Main Building swimming pool
3 15 Finak Gáborné Gombosi Eszter Gyöngyi
Table Tennis Thursday 13:30 15:00 SZEA-EDZ Main Building training room
4 16 Finak Gáborné Gombosi Eszter Gyöngyi
Table Tennis Thursday 15:00 16:15 SZEA-EDZ Main Building training room
4 16 Farkas György
Table Tennis Friday 13:30 15:00 SZEA-EDZ Main Building training room
2 8 Finak Gáborné Gombosi Eszter Gyöngyi
Tennis Monday 18:00 19:00 SPO-MAT Makár Tanya Sports Center (Középmakár dűlő 4.)
2 6 Daróczi Balázs
Tennis Tuesday 17:00 18:00 SPO-MAT Makár Tanya Sports Center (Középmakár dűlő 4.)
2 3 Daróczi Balázs
Training in the Gym Wednesday 12:00 13:30 SPO-GYM Professor Gym (www.professorsgym.hu) (Megyeri str. 4)
2 10 Lipcsik Zoltán
Training in the Gym Friday 12:00 13:30 SPO-GYM Professor Gym (www.professorsgym.hu) (Megyeri str. 4)
4 20 Lipcsik Zoltán
Training in the Gym Friday 13:30 15:00 SPO-GYM Professor Gym (www.professorsgym.hu) (Megyeri str. 4)
4 20 Németh Attila Miklós
UP FP Pharmacy major – obligatory subjects of the 3-4. semester - Course descriptions – academic year of 2018/2019
66
Sport day from to place min.
head-count
max. head-count
trainer
TRX Circuit Training Wednesday 15.00 16.00 SPO-FIT FITNEXX Premium (Jászai Mari u. 2,)
3 7 Solt Edit
Volleyball (men) Wednesday 16:30 18:00 SPO-TCS Sportshall - Jakabhegyi út 6.
2 7 Balla Róbert
Volleyball (women) Tuesday 16:30 18:00 SPO-TCS Sportshall - Jakabhegyi út 6.
2 7 Schrauff Júlia
Yoga Sunday 18:00 20:00 SPO-SOR Sörház (Xavér str 19)
2 10 Kisföldi-Szabó Ágnes
Cardio Yoga Friday 15:00 16:30 SZEA-EDZ Main Building training room
2 10 Ragács Renáta
Zumba (fee payment necessary)
Wednesday 18:00 19:00 SPO-FOR Fordan Dance Center - Batthyány u. 9/a.
2 16 Varga Zsuzsanna
Other sportclubs from Pécs (with permission)
2 20
PTE-PEAC (Sport Club) (with permission)
2 20