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SIMB NEWSNews magazine of the Society for Industrial Microbiology and Biotechnology . July / August 2013 / V.63 N.4 . www.simbhq.org

Summary of 35th Symposium on Biotechnology for Fuels and Chemicals

Job Fair

Sunday, August 12, 20138am - 4pmSheraton San DiegoSan Diego

A job fair will be held in conjunction with the 2013 SIMB Annual Meeting. The fair will run 8am - 4pm at the Sheraton San Diego. Set up will begin at 7am.

Cost for corporate participation$275 SIMB Corporate Member $400 Non-Corporate Member

Includes:• One 2’ x 6’ table in the Job Fair location,

company sign, two chairs

• Access to private interview room through-out the dates of the SIMB Annual Meeting (August 11 - 15)

• Access to resumes

• Announcement of participation on the SIMB annual meeting website including company link

• Discount on 30-day job posting on the SIMB career center site

• Lunch ticket and breaks

Questions? Christine Lowe3929 Old Lee Highway, Suite 92AFairfax, VA 22030www.simbhq.orgemail: [email protected]: 703-691-3357, x 26fax: 703-691-7991

July / August 2013 SIMB NEWS 121

SIMB NewsElisabeth Elder | Editor-in-ChiefDebra Chadick | Associate EditorMelanie Mormile | Associate EditorKristien Mortelmans | Associate Editor

CONTRIBUTING EDITORSPaul Cino | Local SectionsStephanie Groves | Calendar and Book Reviews

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BOARD OF DIRECTORSPresident: Thomas JeffriesPresident-Elect: Leonard KatzPast President: Neal ConnorsSecretary: Rob DonofrioTreasurer: Janet WestphelingDirectors: Scott Baker E. Timothy Davies Jonathan Mielenz Erick VandammeExecutive Director: Christine Lowe

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SIMB News (ISSN 1043-4976), is published bi-monthly, one volume per year, by the Society for Industrial Microbiology and Biotechnology and is mailed to all SIMB members.

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On the cover: Portland, Oregon cityscape with Mount Hood. Image courtesy of Portland Convention and Visitors Bureau.

feature124 Summary of 35th Symposium on Biotechnology for Fuels and Chemicals

news130 Supreme Court says no to patents on human genes131 Scientific organizations defend peer review at NSF131 Short takes 132 Organizations release guiding principles for America COMPETES Act 132 COPUS initatives133 Evonik industries selects OPX Biotechnologies for joint development of bio-based chemicals 134 New enzyme technology saves up to 5% corn in ethanol

members135 Member birthdays

meetings136 2013 SIMB Annual Meeting 148 Recent Advances in Fermentation Technology (RAFT 10)

publications150 Book review: Topics in Ecological and Environmental Microbiology

in every issue122 Corporate members122 Advertisers index151 Calendar of events153 Corporate application

Contact SIMB(703) 691-3357

Executive DirectorChristine Lowe, Ext. 26

Director of Member ServicesJennifer Johnson, Ext. 23

Web ManagerSuzannah Citrenbaum, Ext. 27

Meeting CoordinatorNancy Gorell, Ext. 24

AccountantEsperanza Montesa, Ext. 22

contents SIMB News | July / August 2013 | Vol 63 No 4

corporate members

122 SIMB NEWS www.simbhq.org

Diamond Alberta Innovates Technology Futures Angel Yeast Co., Ltd.Marcor Development CorporationNovozymes, Inc.Pall Life SciencesTAP Biosystems

Gold Amgen, Inc.Appropriate Technical Recourses (ATR, Inc.)Bio SpringerBioengineering, Inc.Biotechnology Industry Organization (BIO)Blue Sens gas sensor GmbHBroadley-James CorporationBugLab, LLCChemglass Life SciencesDCI-Biolafitte Flownamics, Inc.FrieslandCampina Domo Genesis Biosciences, Inc.Golden Leaf Biomanufacturing Training

and Education Center – North Carolina State University

Hamilton Company

Advertisers Index

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feature

Thirty-five years ago, Charles D. Scott established a new conference for sci-entists and engineers working towards biologically-catalyzed routes to fuels and chemicals from renewable resources. The Symposium on Biotechnology in Energy Production and Conservation, which was quickly renamed the Symposium on Bio-technology for Fuels and Chemicals, is the longest-running and one of the larg-est annual meetings focused on biomass resource utilization and commercializa-tion of bio-based fuels and chemicals technologies. This meeting, now span-ning 20 oral presentation sessions and 2 poster sessions over 4 days, is primarily technical in nature. The majority of ses-sions focus on applied and fundamental research in feedstock development and handling, pretreatment technologies, microbial conversion and engineering, biomass conversion enzymology, and process integration, scale-up and biore-finery operations.

Additional topics include societal, economical, and life cycle analyses of bio-based conversion processes as well

as status updates on various conversion research centers and international dem-onstration and commercialization efforts. Conference presentations are weighted towards academic and governmental research, but there is enough coverage of industry efforts and initiatives each year to keep the research presentations focused on applications. As a result, the meeting is generously sponsored by major corporate and institutional play-ers involved in biomass conversion and renewable feedstock-based fuels and chemicals production, and the vendor exhibit, which showcases state-of-the-art biomass conversion research tools, is well attended.

In late April 2013, we held the 35th Symposium on Biotechnology for Fu-els and Chemicals (SBFC) in Portland, Oregon, and it is clear that this annual meeting has come a long way from its early days when it was held in Gatlin-burg, Tennessee and typically attended by 100-200 researchers. The 35th SBFC was attended by over 750 researchers from 31 nations. One hundred and thirty

35th SBFC Meeting SummaryThe 35th Symposium on Biotechnology for Fuels and Chemicals, organized by the Society for Industrial Microbiology and Biotechnology, was held April 29 - May 2, 2013, in Portland, Oregon. The conference brought together students, researchers, and representatives from industry, academia, and governments. Over 750 attendees attended presentations organized into three topic areas: Biomass Resource Supply, Development and Character-ization; Conversion Technologies (Deconstruction or Synthesis); and, Fuels and Chemicals Products (Larger Scale Production and Biorefinery Techno-economic and Sustainability Analyses); as well as Special Topics.


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eight oral presentations were delivered across 20 sessions cov-ering all aspects of bio-based production of fuels and chemicals. The keynote speech, “Biofuels: Making the Case and Making it Work,” was presented by Professor Lee R. Lynd (Dartmouth Col-lege) and described the future importance and potential for us-ing cellulosic biomass in meeting societal, environmental and economic development needs as well as to address food versus fuel land use issues. The banquet speaker, Professor Douglas Eveleigh (Rutgers University), delivered a brilliant and entertain-ing retrospective on the role of cellulases from the dinosaurs to modern plumbing in his witty one-man show, “Cellulase - The Greatest Show on Earth”.

In addition to the excellent array of technical talks, more than 350 posters were presented over two poster sessions, with nearly half of them from students. Every year, the student poster competition is one of the highlights of the meeting, and this year was no exception. Two student poster awards were presented. In the Applied Technology category, Zachary Baer (Energy Biosciences Institute) won for his poster “Integration of chemical catalysis with extractive fermentation to produce blend stocks for jet and diesel fuels,” while Leonardo Da Costa Sousa (Michigan State University) won in the Basic Science cat-egory for his poster, “Fractionation and characterization of lignin from extractive ammonia pretreated corn stover”.

Two key technology awards were also presented at the Thursday night banquet. The Charles D. Scott Award, created in honor of the meeting’s founder, is awarded to an individual

who has demonstrated long-term scientific excellence in the area of biotechnology for biomass conversion and has signifi-cantly advanced the field through their work. This year, the C.D. Scott award was presented to Dr. Liisa Viikari (University of Hel-sinki) for her decades of research in biomass conversion enzy-mology and fermentation. A new award was started this year to recognize the efforts of key organizations in promoting and advancing a bio-based economy. The inaugural Bioeconomy Leadership Award was presented to DuPont for their efforts in all aspects of renewable resource utilization and biomass con-version over many years, including feedstock handling, enzyme and microbe development, process engineering, and integrated technology demonstration and commercialization.

Next year’s 36th Symposium on Biotechnology for Fuels and Chemicals will be held in Clearwater Beach, Florida April 28 – May 1, 2014. This meeting promises to maintain the technical excellence originally envisioned and promoted by Chuck Scott and we look forward to seeing you there.

Steve Decker, Program Chair, 35th SBFC

Jim McMillan, Program Chair, 35th SBFC

Jonathan Mielenz, Program Co-Chair, 35th SBFC

Thomas Klasson, Program Co-Chair, 35th SBFC


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Photo recap 35th Symposium on Biotechnology for Fuels and Chemicals

Website: www.simbhq.org/sbfc

Doug Eveleigh, Rutgers, Banquet Speaker Jim McMillan and Steve Decker, NREL, 2013 Program Chairs

Bottom left and right: Attendees enjoying the banquet


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From top to bottom:

SIMB President Tom Jeffries with C.D. Scott awardee Liisa Viikari, University of Helsinki

Past Symposium awardees Charles Wyman, Mike Himmel, Patrick Foody, Sr., Brian Davison

Best Student Poster Presentation-Applied, Zachary Baer with Jim McMillan

DuPont

About DuPont DuPont (NYSE: DD) has been bringing world-class science and engineering to the global marketplace in the form of innovative products, materials, and services since 1802. The com-pany believes that by collaborating with customers, governments, NGOs, and thought lead-ers we can help find solutions to such global challenges as providing enough healthy food for people everywhere, decreasing dependence on fossil fuels, and protecting life and the environment. For additional information about DuPont and its commitment to inclusive in-novation, please visit www.dupont.com.

About DuPont Industrial BiosciencesDuPont Industrial Biosciences comprises an unmatched portfolio of capabilities in industrial biotechnology and biobased solutions. Harnessing the power of 2,200 talented individu-als worldwide, the organization focuses on providing renewable and sustainable solutions to meet the needs of a growing population while protecting our environment. The unique combination of agricultural, biotechnology, chemical and material science capabilities al-lows DuPont Industrial Biosciences to deliver cost-effective products with superior perfor-mance and sustainability aspects to a range of industries. For more information, please visit: http://biosciences.dupont.com.

Liisa ViikariProfessor, Biorefineries University of Helsinki

Liisa Viikari started in 2007 as invited professor on Biorefineries at the University of Helsinki, Finland. Previously, she acted in various positions and finally as research professor (1995-2007) on Industrial biotechnology at VTT Biotechnology, Finland. She has devoted most of her research activities to the fields of basic and applied enzymology for exploitation and up-grading of renewable lignocellulosic resources. She started her biomass research on hemi-cellulases and extended it later to other enzymes and aspects of biomass conversion, includ-ing the PhD on Zymomonas mobilis. The work has comprised design of optimal enzymes and hydrolysis techniques, fermentation of sugars to a variety of products (ethanol, organic acids acid, methane) as well as biotechnical upgrading of various lignocellulose components into value-added products. In 1985-2000, a significant part of her activities was devoted to bio-technical applications in the pulp and paper applications. Lately, the work on biomass con-version has been financed mainly by the European Union. Her list of publication comprises about 150 original peer reviewed articles, as well as reviews, book chapters and patents. Dur-ing her career, she has been privileged to know and be a friend of many of the main players in the biomass-biotechnology field. Today, gradually retiring, she is able to spend more time with her 3 children and 4 grandchildren.

CD Scott Award

Award winners

Bioeconomy Leadership Award

The DuPont Oval Logo is a trade-mark of DuPont or its affiliates.

Applied Technology Category: Zachary Baer, Energy Biosciences Institute, "Integration of chemical catalysis with extractive fermentation to produce blend stocks for jet and diesel fuels"

Fundamental Category: Leonardo Da Costa Sousa, Michigan State University“Fractionation and characterization of lignin from extractive ammonia pretreated corn stover”

Student poster awards


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Sponsors Exhibitors

Andritz, Ltd.

Applied Instrument

Technologies

Applikon Biotechnology,

Inc.

Benz Technology Interna-

tional, Inc.

Bioengingineering, Inc.

BIOMED Central

Chemglass Life Science

DOE - Office of the Biomass

Program

Eppendorf

Hamilton Company

Labman Automation LTD

m2p-labs, Inc.

Megazyme International

Metabolon, Inc.

NREL

Pall Life Sciences

Tecan US, Inc.

Teknova

Thermo Scienctific

Megazyme Tecan

Gevo

Thank you to the Symposium sponsors and exhibitors

news


PPR

Join SIMB in San DiegoAugust 11-15, 2013

for the 2013 SIMB Annual Meeting at the Sheraton San Diego Hotel and Marina.

Five meeting tracks, special topic sessions, three premeeting workshops, student contributed paper sessions, and poster sessions. Registration and housing now open.

www.simbhq.org/annual

On 13 June 2013 the United States Supreme Court ruled that hu-man genes cannot be patented. The unanimous decision stated that isolating specific genes was not worthy of a patent.

The case considered by the high court dealt with patents held by Myriad Genetics, Inc. for two genes (BRCA1 and BRCA2) that have been linked to breast and ovarian cancer. The company uses the genes to test patients for their risk of developing cancer.

“Myriad did not create anything,” wrote Justice Clarence Thomas on behalf of the court. “To be sure, it found an important and useful gene, but separating that gene from its surrounding genetic material is not an act of invention.”

“Had Myriad created an innovative method of manipulating genes while searching for the BRCA1 and BRCA2 genes, it could possibly have sought a method patent,” Thomas wrote. “But the processes used by Myriad to isolate DNA were well understood by geneticists at the time.”

Despite striking down the patents on human genes, the Su-preme Court did uphold Myriad Genetics’ right to patent cDNA, which is created from RNA that is reverse transcribed via an en-zyme. As one science blogger points out, this is simply a change of

media. “This is like saying you couldn’t patent a recipe on paper, but if you transfer it word for word onto sheepskin, it becomes pat-entable,” wrote Dr. Mark Hoffnagle on his blog about denialism.

Dr. Francis Collins, the director of the National Institutes of Health, praised the court’s decision: “The right to control exclu-sively the use of a patient’s genes could have made it more difficult to access new tests and treatments that rely on novel technologies that can quickly determine the sequence of any of the estimated 20,000 genes in the human genome. Such approaches form the cornerstone of the rapidly emerging field of personalized medi-cine, in which diagnostic, therapeutic, and preventive strategies can be tailored to each person’s unique genetic makeup.”

There are roughly 4,000 gene-related patents in the United States.

This article is reproduced with permission from the AIBS Public Policy Report, Vol. 14, Issue 12, June 17, 2013. © American Institute of Biological Sciences, 2013.

Supreme Court says no to patents on human genes

news


Short takes

• The Ocean Studies Board of the National Research Council is seeking nominations for potential committee members for a new study. “A Decadal Survey of Ocean Sciences: Guidance for NSF on National Ocean Research Priorities” was requested by the National Science Foundation. Nominations are due by 17 June 2013 and can be submitted at http://www.surveygiz-mo.com/s3/1260708/Nominations-for-OSB-Decadal-Survey.

• The National Science Foundation is accepting proposals for the Advancing Digitization of Biodiversity Collections pro-gram. This initiative seeks to enhance and expand digital data documenting existing vouchered biological and pale-ontological collections. The deadline for full proposals is 18 October 2013. More information is available at http://www.nsf.gov/pubs/2013/nsf13569/nsf13569.htm.

• The U.S. Department of Agriculture plans to deploy a new grants reporting system, REEport, to replace the exist-ing Current Research Information System. The new system

would implement a uniform format for reporting perfor-mance progress on federally funded research projects. Learn more at http://www.gpo.gov/fdsys/pkg/FR-2013-06-07/html/2013-13571.htm.

• Researchers from the U.S. Forest Service have developed a new tool for forest resource managers to identify regions fac-ing multiple threats, including wildfires, insects and disease, and land-use change. The study is published in the May 2013 issue of the Journal of Forestry.

This text is reproduced with permission from AIBS Public Policy Reports, Vol. 14, Issues 12, June 17, 2013 © American Institute of Biological Sciences, 2013.

More than 100 organizations have signed a letter to Congress in defense of peer review. The letter was prompted by recent congres-sional actions that called into question the merit review process used by the National Science Foundation (NSF) to award research grants.

“It is imperative that NSF’s system of support for basic re-search be based upon excellence, competitive scientific merit, and peer-review,” states the letter. “While Congress does play an important role in oversight of federally funded research, it should avoid legislative attempts that could undermine a decades-long system of success and ultimately impede discovery and innovation.”

Among the congressional actions that prompted concern within the scientific community is the High Quality Research Act, a draft bill that would require the director of NSF to certify that any grant is of the highest quality, in the best interests of the United States, and not duplicative of other research efforts.

Three former directors of NSF and three former chairmen of the National Science Board spoke out against the draft bill in a recent letter to the leaders of the House Science, Space, and Tech-nology Committee. The former NSF leaders said that the draft bill

would have “a chilling and detrimental impact on the merit-based review process.”

The American Institute of Biological Sciences contributed to the letter and was one of the organizations to sign the letter. AIBS member organizations endorsing the letter included: American Society of Agronomy, American Society of Ichthyologists and Herpetologists, American Society of Plant Biologists, Associa-tion of Ecosystem Research Centers, Association for the Sciences of Limnology and Oceanography, Botanical Society of America, Crop Science Society of America, Ecological Society of America, Entomological Society of America, Genetics Society of America, Long Term Ecological Research Network, National Association of Marine Laboratories, Natural Science Collections Alliance, Soci-ety for Behavioral Neuroendocrinology, and Soil Science Society of America.

Read the letter at www.aibs.org/position-state-ments/20130520_nsf_peer_review.html.

This text is reproduced with permission from the AIBS Public Policy Report, Vol. 14, Issue 11, June 3, 2013. © American Institute of Biological Sciences, 2013.

Scientific organizations defend peer review at NSF

news


The scientific community is gearing up for congressional consideration of a law that affects basic federal research. Congress is expected to soon address legislation that sets funding authorization levels and policy directives for the National Science Foundation (NSF) and other federal sci-ence agencies.

In anticipation of congressional ac-tion, 118 scientific organizations and uni-versities have crafted guiding principles

Organizations release guiding principles for America COMPETES Act

for the America COMPETES Act reautho-rization. The guidelines call for “steady and sustained real growth in funding for all of the major federal research agencies.” Other highlights include preservation of peer review and reduction of unneces-sary or duplicative federal regulations. In terms of education and workforce issues, support for science education programs and high-skilled immigration reform are identified as priorities.

The America COMPETES Act was last considered by Congress in 2010. The law set funding guidelines for NSF for three years, which will expire this year.

This article is reproduced with permission from the AIBS Public Policy Report, Vol. 14, Issue 11, June 3, 2013. © American Institute of Biological Sciences, 2013.

A bipartisan group of lawmakers have in-troduced legislation to create the position of Science Laureate for the United States. The bill would allow the President to ap-point up to three Science Laureates to en-gage the public and increase public aware-ness of science. Appointments would be made on the basis of an individual’s sci-entific contributions and ability to foster public interest in science. If you support the establishment of a Science Laureate, you can send a letter (http://capwiz.com/aibs/issues/alert/?alertid=62675261) to your Representative and Senators asking them to co-sponsor the Science Laureates of the United States Act of 2013.

COPUS initiativesVoice your support for a Science Laureate

Are you interested in providing science, technology, engineering, and math-ematics (STEM) programming in public libraries?

The STAR_Net project (http://com-munity.starnetlibraries.org), which is funded by the National Science Foun-dation to bring STEM to libraries, has launched a new online community web-site (http://community.starnetlibraries.org). This community is for library staff that want to provide STEM programs and the STEM professionals who want to help them. The site allows visitors to share information; find resources and partners for program development; and explore

Provide STEM programming to public libraries

best practices for providing quality STEM programming.

If you want to connect with others who share your interest in developing STEM programming for library patrons, please submit a listing to the Directory on the community site. For more infor-mation, please contact: Lisa Curtis, [email protected] or 720-974-5821, or Anne Holland, [email protected] or 720-974-5876.

COPUS facilitates public understanding of science. To learn more, visit www.copusproject.org. © American Institute of Biological Sciences, 2013. All rights reserved.

news


Fit to Print

Evonik Industries selects OPX Biotechnologies for joint development of bio-based chemicals

IOPX Biotechnologies, Inc. (OPXBIO) and Evonik Industries AG have announced the two companies have entered into an agreement to jointly develop certain bio-based specialty chemicals. The joint-de-velopment agreement, signed 3 May 2013, calls for OPXBIO to use its proprietary EDGE™ (Efficiency Directed Genome Engineering) technology to develop the bio-processes.

“There’s a growing market demand for more sustainable products and pro-cesses, and OPXBIO is an excellent part-ner to help us meet that demand because their technology can create high-value, bio-based chemicals quickly and cost-effectively,” said Dr. Thomas Haas, Vice President Science-to-Business Center Biotechnology of Creavis, the strategic research and development unit of Evonik.

“Evonik is a leading global specialty chemicals company, and we’re looking for-ward to helping them expand their portfo-lio of bio-based chemicals,” said Charles R. (Chas) Eggert, OPXBIO president and CEO. “The bio-process we’re developing has the potential to create economic and sustainable versions of products we use in our everyday lives.” According to the agreement, OPXBIO will also be able to market bio-based products resulting from the Evonik collaboration.

About OPXBIOOPX Biotechnologies (OPXBIO) is a leader in sustainably transforming the business of chemistry. As the "Good Chemistry" company, OPXBIO provides more sus-tainable value to customers by applying its proprietary EDGE ™ (Efficiency Directed Genome Engineering) technology to pro-duce economic, bio-based chemicals that directly replace existing petroleum-based products. OPXBIO's EDGE is versatile and enables faster, more efficient devel-opment of bioprocesses using a variety of feedstocks. Founded in 2007, OPXBIO is financed by leading venture capital inves-tors, and employs 65 people in Boulder, Colorado. For more information, visit www.opxbio.com.

About EvonikEvonik, the creative industrial group from Germany, is one of the world leaders in specialty chemicals. Profitable growth and a sustained increase in the value of the company form the heart of Evonik’s cor-porate strategy. Its activities focus on the key megatrends health, nutrition, resource efficiency and globalization. Evonik ben-efits specifically from its innovative prow-ess and integrated technology platforms.

Evonik is active in over 100 countries around the world. In fiscal 2012 more than 33,000 employees generated sales of around €13.6 billion and an operating profit (adjusted EBITDA) of about €2.6 billion.

Evonik Media Contact Dr. Karin AßmannSpecialty PressEvonik [email protected]

OPXBIO Media Contact Andy YbarraWeber [email protected]

news


New enzyme technology saves up to 5% corn in ethanol New technology allows the biofuels industry to produce more ethanol with less corn while saving energy and improving profits.

Novozymes today announced the launch of new enzyme technology that can in-crease ethanol yield from corn by up to 5%. The technology also increases corn oil extraction by 13%, while saving 8% energy.

The efficiency improvements can be achieved when two new enzymes, Spiri-zyme® Achieve and Olexa®, are used to-gether with another Novozymes enzyme, Avantec®.

“These new enzyme innovations offer strong benefits to ethanol producers,” says Andrew Fordyce, Executive Vice President for Business Operations at Novozymes. “It allows our customers to make more from less and substantially improve their profit margins”.

A typical U.S. ethanol plant uses around 36 million bushels (900,000 tons) of feed-grade corn per year to produce 100 million gallons of fuel ethanol, 300,000 tons of animal feed (DDGS) and 8,500 tons of corn oil. By using Avantec, Olexa and Spirizyme Achieve, such a plant can save up to 1.8 million bushels (45,000 tons) of corn while maintaining the same ethanol output, increasing corn oil extrac-tion, and generating up to $5 million in additional profit.

High yield, low riskAvantec was introduced in October 2012 and has been well received in the U.S. eth-anol industry.

“Our customers demand risk-free options that do not require major invest-ments,” says Andrew Fordyce. “That is exactly what our enzymes offer. We are the first to market this full package and are looking forward to implementing it together with our customers, trialing the technology at their plants, and getting the solutions out there. It’s a competitive in-dustry and only via innovation like this can Novozymes continue to be the lead-ing supplier of enzymes to the ethanol industry”.

Corn is the key raw material in bio-fuel production in the U.S. and by far the biggest cost component for an ethanol plant. After the corn is harvested, the ker-nels are ground into corn meal and water added to make a mash. Enzymes convert the starch in the mash to sugar, which can then be fermented to ethanol. Avantec and Spirizyme Achieve convert starch to sugar more efficiently than any other enzyme product on the market, while Olexa works by freeing up oil bound in the corn germ.

Corn oil is used in the production of animal feed, biodiesel and soaps, and has become an increasingly important rev-enue stream for ethanol producers. Exten-sive implementation of extraction tech-nology from 2008 to 2012 has seen the in-dustry record a nearly five-fold increase in corn oil production, according to a study by the University of Illinois at Chicago. Novozymes estimates that approximately

80% of the operating ethanol capacity in the U.S. will have incorporated oil extrac-tion into their plants by end 2013.

The U.S. is the world’s biggest biofuels producer, and ethanol today accounts for approximately 10% of gasoline consump-tion in the U.S. transportation sector.

Novozymes Media Contact Paige DonnellyCommunications ManagerNorth AmericaTel: +1 919 494 3209Mobile: +1 919 218 [email protected]: @Rribbit

members


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SIMB wishes the following members a Happy Birthday!

meet ings


2013 SIMB Annual MeetingAugust 11 - 15, 2013 (Sunday-Thursday)Sheraton San DiegoSan Diego, CA, USA

Web site: www.simbhq.org/annual

Registration and HousingOpen

Welcome from the Program ChairDear Colleagues,On behalf of the organizing committee, it is my pleasure to invite you to the 63rd Annual Meeting of the Society for Industrial Mi-crobiology and Biotechnology to be held August 11 to 15, 2013 at the Sheraton San Diego in San Diego, California. This year’s theme is “The Evolution of Microbial Biotechnology throughout the Ages”.

Sessions discussing classic and well known microbial tech-nology such as Beer and Wine Fermentation, Biopharmaceutical Production, Natural Products development, and Bioremediation will be featured, as well as modern cross-functional techniques and applications like Computational Design, Functional Metage-nomics, Microbial Consortia Synergies, Biofuels and Biochemi-cals. Furthermore, novel tools and approaches will be presented, which cover advances in High throughput Microbioreactor tech-niques, Systems Biology and Synthetic Biology for both well-known and non-conventional microorganisms, complete with examples of their application in various fields, such as Biocataly-sis, Natural products, and Biochemicals development.

As in previous years, this meeting will also provide an excellent opportunity for networking with a diverse group of world-lead-ing experts and fellow scientists from industries, academics and government organizations. Likewise, it also represents an excel-lent venue for student participations, with many student centric oral and poster presentation opportunities.

The 2013 Annual Meeting will have something for every-one, from experts to novices within industries, academics and re-search organizations from around the world, and I look forward to enjoying a fruitful scientific gathering with you.Join us for this wonderful event in sunny Southern California.

Sincerely,Helia Radianingtyas, Synthetic GenomicsProgram Chair

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Program CommitteeProgram ChairHelia RadianingtyasSynthetic GenomicsHelia.radianingtyas@synthetic genomics.com

Organizing CommitteeBiocatalysis Patrick Cirino Univ. of [email protected]

Shelley CopleyUniv. of [email protected]

Debbie [email protected]

EnvironmentalMelanie MormileMissouri M&[email protected]

Enrico MarsiliDublin City Univ., [email protected]

Don CowanUniv. of Pretoria, South [email protected]

Fermentation/Cell Culture

Noel [email protected]

David HogsettOPX

Goutham [email protected]

Metabolic EngineeringKristala Jones [email protected]

Brian PflegerUniv. of [email protected]

Steve van [email protected]

Hal AlperUniv. of Texas at [email protected]

Natural Products

Paul JensenUniv. of California, San [email protected]

Huimin ZhaoUniv. of [email protected]

Brian [email protected]

Hotel and travelSheraton San Diego Hotel and MarinaSan Diego, CARoom rate: $159 single/double + tax; rate includes complimentary internet in sleep-ing rooms and complimentary fitness cen-ter when booking through the SIMB link (available 3/1/2013). A balcony is included with each room. Limited number of per diem rooms available. Enjoy the beautiful San Diego city skyline, bay and marina views at Sheraton San Diego Hotel and Marina, just minutes from the historic Gaslamp District, Seaport Village, the San Diego Convention Center, the San Diego Zoo and many other great attractions. The hotel also offers 4 restaurants and a Starbucks, 3 swimming pools, tennis courts, spa and a pedestrian path that runs from outside the hotel and around a por-tion of San Diego Bay. The Sheraton pro-vides complimentary shuttle service from the airport.

EventOuting to Birch Aquarium, La Jolla, CA

Sign up deadline: July 15, 2013.

When: Wednesday, August 14, 6pm – 10pmCost: $70 and includes:

• Round trip bus transportation from the Sheraton San Diego Hotel and Marina to Birch Aquarium and return

• Open Bar with beer, wine, soft drinks, juices

• Snacks• Buffet Dinner• Exclusive SIMB attendee access to the

Birch Aquarium including all exhibits and grounds, as well as world class views

To register, visit: www.simbhq.org/annual/events/

SponsorshipProvide visibility to your organization and promote your brand. There are a variety of sponsorship benefit packages and op-portunities for organizations of all sizes. Enhance your exposure and position your company as a leader in the industry with sponsorship. Download the sponsorship form at: www.simhq.org/docs/annual/AM2013sponsorship.pdf. For more information, contact Chris Lowe ([email protected]).

ExhibitsThe exhibit prospectus is now available. For information, contact Nancy Gorell ([email protected]).

AdvertisingAdvertising is available in the meeting program. Deadline for submission of ads is June 1, 2013. For information on rates, con-tact Chris Lowe ([email protected]).

Job FairAugust 12, 20138am – 4pm Sheraton San Diego

The 2013 SIMB Job Fair will be held in con-junction with the SIMB Annual Meeting . Set up will begin August 12 at 7am.

For more information, visit: http://www.simbhq.org/annual/job-fair/.

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Sponsors Exhibitors

Alberta Innovates Technology Futures Angel Yeast Co., Ltd.Applied Instrument TechnologiesBASF The Chemical CompanyBioengineering, Inc.Bio Springer Biolog, Inc.Bio-Technical Resources (BTR) Blue Sens gas sensor GmbH Broadley-James Corporation BugLab, LLC Charter Medical, Ltd.Chemglass Life Science DCI-Biolafitte Effinity Tech, Inc.Eppendorf FrieslandCampina DomoGenScript USA, Inc.Global BioIngredients, Inc. Golden Leaf Biomanufacturing Training and Education CenterHamilton Company Hiden Analytical, Inc.Kuhner Shaker, Inc. Lallemand, Inc. Life Technologies Corporation M2P Labs, Inc. Marcor Development Corp. Moubio, LLCoptek-Danulat, Inc. Pall Life Science Panlabs Biologics, Inc.Roquette America, Inc.Sartorius Stedim BiotechSensient Bio-Ingredients Society for Applied MicrobiologySolabia Group Stratophase, Ltd.TAP BiosystemsTeknovaTraders Protein University of Georgia

Advertising

Advertising is available in the meeting program.

Advertising rate sheet and space reservation form available at:http://www.simbhq.org/docs/MPadrates2013_fillable.pdf.

Contact Suzannah Citrenbaum 703.691.3357 ext. [email protected]

Exhibiting

Exhibit spaces available. See prospectus online.

ContactNancy Gorell, 793.691.3357 ext. [email protected]

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Biocatalysis

Modeling and Computational DesignSagar Khare (Rutgers Univ.)

Chemo Enzymatic Approaches to BiocatalysisSylvie Garneau-Tsodikova (Univ. of Michigan)

Novel TransformationsJon D. Stewart (Univ. of Florida)

Enzymes for Hydrolysis of LignocellulosicsDebbie Yaver (Novozymes), Regine Behr (Novozymes)

To enable second generation ethanol and chemical produc-tion from lignocellulosic biomass cost effective biocatalysts for hydrolysis are essential. This session will focus on recent discoveries in both enzymes and microorganisms for biomass hydrolysis including synergy between commercial cellulases and cellulosomes, bacteria that can metabolize lignin and enzymes that can degrade native lignin molecules. New in-sights into mechanisms and structures of cellulases will also be discussed.

Environmental

Microbial Ecology for Industrial SettingsMatthew Fields (Montana State University)

Functional Metagenomics and Gene DiscoveryDon Cowan (Univ. of Pretoria)

BioremediationMelanie Mormile (Missouri M&T)

BioelectrosynthesisEnrico Marsili (Dublin City Univ., Ireland)

Microbial Consortia / Population SynergiesCynthia Collins (Rensselaer Polytechnic)

The potential of microbial consortia for use in biotechnology, bioprocessing and other applications has reemerged as an active area of research. Like their natural counterparts, engi-neered microbial consortia can perform complex functions by distributing tasks. Combinations of microbes have also been observed to exhibit increased production rates and metabolic efficiency compared to monoculture systems. Challenges in this nascent field include our ability to reliably control com-munity composition and function. This session will highlight both novel approaches for coordinating microbial commu-nity behavior and application that use microbial communities. Topics of interest include, experimental and computational tools for screening and predicting community behavior, cell-

cell communication and synthetic biology approaches for understanding or controlling ecosystem behavior, and meta-bolic engineering at the community level.

Fermentation and Cell Culture

Miniature bioreactors in strain developmentGoutham Vemuri (BioAmber), Katy Kao (Texas A&M)

Rational design of proteins or metabolic network itself has not matured to enable targeted engineering of biological sys-tems. Therefore, there is a substantial amount of dependent on mutagenesis to create diversity. With the advancement of high throughput and miniature bioreactors, there is a ripe op-portunity to develop excellent screens and also test a broad variety of conditions. This session will focus on the role of miniature bioreactors in screening and strain development process. In addition, the application of small-scale bioreactors for use in evolutionary engineering will also be discussed. The engineering aspects of the miniature bioreactors, fabrication and validation are also within the scope of this session.

Fermentation of Non-Conventional Yeast & BacteriaQuinn Zhu (DuPont)

Genomic Stability in Fermentation ProcessesChandresh Thakker (Rice Univ.), Clementina Dellomonaco (DuPont)

Maintaining genome stability is crucial for the success of in-dustrial fermentation processes. This session will focus on the impact of fermentation modes and environmental condi-tions, metabolites, and stress on host and plasmid stability. Additionally, it will provide insights into new approaches and methodology for developing genetically robust strains to im-prove fermentation performance.

Beer and Wine FermentationTorben Bruck (Pfenex), Noel Fong (Nucelis)

Beer and winemaking are the oldest fermentations known. In this session, we will provide updates on strain characteriza-tion and modification, chemistry during the fermentation, substrate effects on flavor, and predictors of quality.

Production of BiopharmaceuticalsTom Kelleher (Amgen) & Tiffany Rau (Eli Lilly)

Changes in Regulatory Expectations, Production Systems, Safety Standards and Cost Structures are driving a much deeper understanding of Biopharmaceutical Manufacturing. Commercial production opportunities and issues, which di-rectly impact product quality, have emerged from these driv-ers. The exploration of quality is enabled by a revolution in communication, analytical science, and process monitoring.

Session Topics with selected session descriptions

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Our ability to discern and control more parameters is having wide-ranging impact as commercial biopharmaceutical man-ufacturing moves into a global future.

Production of BiochemicalsDan Solaiman (USDA/ARS) and Robert Fireovid (USDA/ARS)

Fermentative production of biochemicals in a biorefinery set-ting will be emphasized in this session. Biorefinery takes its root from the well-developed petroleum-refinery process in which every output-stream is efficiently utilized either “as-is” (fuels) or as feedstocks for petrochemicals (detergents, plas-tics, etc.). Thus, in a broad sense, a biorefinery feeds on renew-able plant- or animal-based biofeedstocks to produce multiple biobased products (which could include fuels) for industrial application. Within this context, presentations in this session will showcase various fermentation processes that can be or have potential to be incorporated into a biorefinery, so as to maximize the utilization of incoming biofeedstock materials for the production of value-added biobased products.

Metabolic Engineering

Biofuels I: Integrated Approaches for Sustainable and Cost-Efficient Biofuels ProductionAndreas Schirmer (LS9)

The major driver for future success of biofuels is the develop-ment of cost-efficient and scalable processes based on sus-tainable feedstocks. Rising feedstock costs, moderate crude oil prices and other macroeconomic factors have made this endeavor a formidable challenge. Overcoming the obstacles for sustainable and cost-efficient biofuels production will re-quire interdisciplinary and integrated approaches. This session focuses on contributions that aim at combining state-of-the art Metabolic Engineering with exploiting low-cost feedstocks and/or leveraging innovative production technologies to-wards biofuels.

Metabolic Engineering and Synthetic Biology Approaches for Advanced Biofuels SynthesisCong T. Trinh (Univ. of Tennessee)

Recent research has focused on engineering microbial bio-catalysts to synthesize “drop-in” advanced biofuels. The chal-lenges are that these biocatalysts have low yields, titers, and productivities and are engineered under conditions that are not practical for industrial scale-up processes (e.g., simple sugars, complex medium, aerobic condition, free of inhibi-tors). This section will focus on contributions that present the state-of-the-art metabolic engineering and synthetic biology approaches to address these challenges.

Metabolic Engineering for Basic and Intermediate Chemicals ProductionSteve van Dien (Genomatica)

Industrial chemicals are the building blocks for a multitude

of polymers that make up many of the products we use in our daily life, and are currently produced almost exclusively from petrochemical feedstocks. The use of microorganisms to convert biobased feedstocks to these same products is emerging as a transformational technology for sustainable chemical production. Rapid advances in metabolic engineer-ing, systems biology, and synthetic biology have contributed to recent success in this field. This session will cover develop-ment of microorganisms and fermentation processes for the production of commodity chemicals from sugars or other bio-based feedstocks, and the approaches used to develop them. Various stages of the research workflow will be covered, from proof-of-concept research to commercial success stories.

Metabolic Engineering for the Production of Fine Chemicals and Pharmaceutical PrecursorsDavid R. Nielsen (Arizona State Univ.)

Fine chemicals and pharmaceutical precursors are used as building blocks to produce many important specialty prod-ucts and drugs. Today, however, these products are produced almost exclusively from petrochemical feedstocks according to chemocatalytic production routes. Alternatively, microor-ganisms can be engineered and used as biocatalysts to con-vert biobased feedstocks to the same fine chemicals and phar-maceutical precursors. As the use of biocatalysts can reduce energy and solvent consumption while also offering higher chemo-, regio-, and stereo-specificity, this approach is emerg-ing as a transformational and sustainable technology. Rapid advances in metabolic engineering, systems biology, and synthetic biology have contributed to recent success in this field. This session will cover development of microorganisms and fermentation processes for the production of fine chemi-cals and pharmaceutical precursors from sugars or other bio-based feedstocks, and the approaches used to develop them. Various stages of the research workflow will be covered, from proof-of-concept research to commercial success stories.

Metabolic Engineering of Non-Traditional Host MicroorganismsChristie Peebles (Colorado State Univ.)

Natural Products

New Development in Natural Product BiosynthesisBrian Bachmann (Vanderbilt)

A renaissance is underway in the field of natural product bio-synthesis. The combination of the sudden availability of stag-gering amounts of secondary metabolic genomic sequence data, breakthroughs in structural biology of long intractable biosynthetic systems, advances in analytical methodologies, and an explosion of powerful methods in synthetic biology have converged to underline the centrality of natural prod-uct biosynthetic studies in such chemical biological research. Remarkably, these breakthroughs are completely synergistic and it is becoming commonplace for research programs to

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integrate biosynthetic studies with synthetic biology, natural product discovery (new and unnatural), evolutionary biology, ecological chemistry and structural biology. This session ex-emplifies interdisciplinary research programs representative of this renaissance period in secondary metabolite research.

New Methods for Natural Product ChemistryPaul Jensen (Scripps Institute of Oceanography/UCSD), Eric Schmidt (Univ. Utah)

The National Institutes of Health have long supported the field of natural products research. This has proven particularly im-portant in an era where large pharma has moved away from natural products as a drug discovery platform. This session de-rives its name from an ongoing NIH-supported program de-signed to “reinvigorate the investigation of nature as a prolific source of small-molecules” and to “stimulate the development of a new generation of methods for natural products chemis-try”. This session will feature new approaches to natural prod-ucts research, ranging from genomics to mass spectroscopy, that are being explored as part of this NIH funded program.

Cyanobacterial Natural Products and Metabolic EngineeringWilliam Gerwick (Scripps Institute of Oceanography/UCSD)

Marine cyanobacteria have been revealed to be extraordi-narily rich sources of novel organic molecules with utility to both drug discovery and biofuel applications. In the drug discovery area, the metabolites of these organisms have an amazing diversity of molecular architectures that are largely created from the modular Polyketide Synthase (PKS) and Non-Ribosomal Peptide Synthetase (NRPS) biosynthetic pathways. As a result, these metabolites possess novel pharmacological properties with potential biomedical utility to many human diseases, including cancer, inflammation and infectious dis-eases. Moreover, as modular pathways, they are amenable to genetic manipulation and pathway engineering. On the biofu-els focus, cyanobacteria have been revealed to produce a wide range of hydrocarbon oils with drop-in-ready fuel character-istics. At least two distinct biosynthetic pathways are utilized by cyanobacteria to make these distinctive molecular species, and these also are amenable to manipulation through genetic engineering. Hence, this session will explore through six ex-ceptional presentations the chemistry, biosynthesis and meta-bolic engineering of marine cyanobacterial metabolites with applications in medicine and next-generation biofuels.

Synthetic Biology for Natural Product Discovery and DevelopmentHuimin Zhao (Univ. of Illinois)

The Future of Natural Products in Drug Discovery: RoundtableWilliam Fenical (Scripps Institute of Oceanography/UCSD)

This session will focus on the changing dynamics of microbial drug discovery in the “Omics Era.” This session will be com-

posed of four 30 minute presentations from experts in the field of microbial drug discovery. Topics will encompass inno-vations in the cultivation of “uncultured” strains, the increasing role of genomic mining and using genomic probes in the dis-covery of novel bioactives, and innovative ways in which natu-ral products can be translated into drugs. The presentations will be followed by a Round Table discussion with audience participation to amplify and probe aspects of these topics.

Special Topics

Intellectual PropertySarah Lau (Kilburn & Strode LLP)

Synthetic Biology I ToolsHoward Salis (Penn State)

Synthetic Biology II ApplicationsKirsten Benjamin (Amyris)

This session will highlight diverse recent applications of syn-thetic biology for industrial and biomedical solutions. In-dustrial applications include novel microbial production of chemicals and materials. Biomedical applications include drug production and delivery, environmental sensors, biofilm modulation, and more.

Algae: Engineered Strains/Engineered Production SystemsPhilip Pienkos (NREL)

System Biology: ApplicationsGoutham Vemuri (BioAmber)

Premeeting Workshops

Student contributed papers

Two poster sessions

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Workshop 1Fermentation BasicsOrganizer: Mark Berge, Medimmune

This workshop’s focus is to provide individuals with an introduc-tion to fermentation concepts in industrial settings. The work-shop will be lecture-based with visual aids to help the attendees understand the fermentation principles discussed. The work-shop will be broken into sections based upon the topics that are being presented. After each section has been completed, the attendees will be given real life fermentation case studies that they will work through to reinforce the just discussed topics. The first section of the workshop will include topics on fermenter de-sign including aspect ratios, agitator design, sparger design and sterilization of equipment and media. The second section will deal with actual operational issues of fermentation processes. Included will be discussions about media considerations, foam control strategies, shear, mixing, aeration, feeds and different types of fermentations and the controls involved. The workshop will finish with a section that covers issues involved in scale-up to production size fermentors. See the full workshop schedule and problem sets at www.simbhq.org/annual/annual-meeting-workshops/.

About the organizerSince 2010 Mark Berge has been Sr. Scientist at MedImmune, Inc. in the Process Cell Culture & Fermentation group leading a team responsible for fermentation and cell culture process develop-ment activities. From 2006 to 2010, he was Sr. Scientist at Amgen Inc. in the Cell Science & Technology group developing process-es for therapeutic protein production using fermentation. From 1999 to 2005, Mark was Sr. Scientist at Pfizer Inc. in the Global Biologics division, developing processes for therapeutic protein production using cell culture. From 1995 to 1999, he was Process Engineer at FermPro Manufacturing in deep tank toll manufac-turing for varied customers of food grade materials. Mark holds a BS and MS in chemical engineering from the University of New Hampshire.

Three pre-meeting workshops at SIMB 2013All-day workshops will be held Sunday, August 11, 8am-4pm, at the Sheraton San Diego.

Workshop 2Shake Flask Fermentation EngineeringOrganizer: Duen Gang Mou, Moubio Fermentor Shop

This one day workshop covers small fund hands-on fermentation laboratory basics from flask shaker’s to jar fermentors assembling, cleaning, maintenance, autoclaving, instrumentation for monitor-ing and control, to basic process calculations & diagnostics, novel flask-fermentor hybrid vessel and high experiment turnover for fermentation microbiologist of all trades. Lecture and Powerpoint slides will aid discussions on fundamentals of microbial fermen-tation from flask to jar fermentor and pilot to production plant. This workshop is also about practical lab culture revolution where small and simple are transformed into speed and smart, hundreds and thousands of dollars in expenses can respectively par the har-vest of thousands and tens of thousands of dollars. See the full workshop schedule and items to bring to the work-shop at www.simbhq.org/annual/annual-meeting-workshops/.

About the organizer Duen Gang Mou has worked with the Bristol-Myers Industrial Division Plant in Syracuse, NY (1979-1980); Eastman Kodak Biosciences Research Laboratories in Rochester, NY (1980-1986); Development Center for Biotechnology in Taiwan (1986-2001); and as a visiting professor of the MIT Bioprocess Engineering Program at the Malaysia University of Sciences and Technology (2002-2005). He has broad experience in bio/pharma R/D and fer-mentation consulting; research management support; advising in government science and technology programs; providing mar-ket/industrial information services; adjunct teaching of under-graduate and graduate students; developing biotech businesses; developing industrial liaisons; and networking governmental-in-dustrial-educational entities. His publications include 2 books on Chinese biotechnical businesses; 10+ US/international patents; and 50+ publications in technical journals, conference poster ses-sions, and conference presentations. Since founding MOUBIO in 2001 Dr. Mou has focused on developing, patenting, and manu-facturing palm-size, tabletop, plug-and-play stirred engineering vessel systems for microbiological and everyday lab use. Dr. Mou is a 30+ year member of the American Chemical Society and SIMB.

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Workshop 3Introduction to Design of Experiments (DoE) for Bioprocess Analysis and OptimizationOrganizer: Marcello Fidaleo, Biomanufacturing Training and Education Center (BTEC) (Raleigh, NC, USA), Univ. of Tuscia (Italy)

The aim of this workshop is to provide the attendees with an in-troduction to the Design of Experiments (DoE) methods applied to analysis and optimization of bioprocesses. The workshop fo-cuses on the practical application of DoE methods through the use of lectures, JMP statistical software (SAS Institute) and bio-process case studies. The case studies, which focus on microbial fermentation and provide real data, look at the effects of factors such as medium components, induction temperature, and time on protein (product) production. Attendees will receive a practi-cal overview of the following topics: basic statistical concepts re-quired for DoE (hypothesis testing, confidence intervals, statistical models and Analysis of Variance – ANOVA); how to use factorial, fractional factorial, and response surface designs for the charac-terization and optimization of bioprocesses; how to interpret the output of experimental design software (normal probability, in-teraction, contour and residual analysis plots or ANOVA tables for factorial or surface response models). The workshop is targeted at all those interested in bioprocess development and optimization, particularly those new to DoE techniques. See the full workshop schedule and items to bring to the work-shop at www.simbhq.org/annual/annual-meeting-workshops/.

About the organizer Dr. Marcello Fidaleo is an assistant professor at the University of Tuscia, where he teaches unit operations and design and analysis of experiments for the food industry. He also holds an appoint-ment as a teaching fellow at BTEC. His research interests include modeling of membrane processes and enzymatic and micro-bial processes in the area of food biotechnology. He has carried out research as a visiting scholar at the Biotechnology Institute of the University of Minnesota and as a Fulbright scholar at the Department of Chemical and Biomolecular Engineering of North Carolina State University. Dr. Fidaleo holds a master’s degree in chemical engineering from the Sapienza University of Rome and a doctorate in food biotechnology from the University of Tuscia.

SIMB Annual MeetingJob Fair

August 12, 20138am – 4pmSheraton San Diego

Job seekersBring your resume to the Job Fair and meet one-on-one with company repre-sentatives. Send resumes to [email protected] (Jennifer Johnson) by April 22. Private interview room available all week during the meeting.

Corporate tablesDownload an application to register a corporate table (PDF) at www.simbhq.org/annual/job-fair/. For more informa-tion on setting up your corporate table or providing a resume for the fair, contact: Bob Berger, SIMB Placement Chair ([email protected]).

Cost for corporate participation$275 SIMB Corporate Members$400 Non-Corporate Member.

Includes: • One 2’ x 6’ table in the Job Fair

location, company sign, two chairs• Access to private interview room

throughout the dates of the SIMB annual meeting (August 11 – 15)

• Searchable resumes available• Announcement of participation

on the SIMB website including company link

• Discount on 30-day job posting on the SIMB career center site

• Lunch ticket and breaks

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SIMB is pleased to announce that Amgen has been awarded the 2013 SIMB Industry Award for Discovery, Innovation, and Develop-ment in Industrial Microbiology and Biotechnology. The Industry Award lecture will be presented Monday, August 12 at 4:30 pm dur-ing the SIMB annual meeting. The award lecture will be presented at this time by Jim Thomas, VP, Process and Product Development, Amgen. A plaque will be presented to Amgen at the evening banquet on Tuesday, August 13.

About AmgenAmgen discovers, develops, and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing novel medicines from lab to manufacturing plant to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease, and other se-rious illnesses. With a broad and deep pipeline of potential new medicines, Amgen is committed to advancing science to dra-matically improve people’s lives.

For more information, visit www.amgen.com.

An interdisciplinary approach to R&DFor more than 30 years, Amgen has been a leading innovator in the identification, isolation, production, and use of human pro-teins as therapeutic agents. We focus on pioneering treatmentsfor serious illness. Our R&D organization has cultivated exper-tise in multiple treatment modalities—large-molecule proteins, small molecules, and antibodies—allowing us to choose the best target for attacking disease and to use the modality most likely to affect that target.

A pioneer in biotechnology manufacturingWorking from deep experience and expertise, Amgen’s manu-facturing, process development, quality and distribution teams ensure the quality and supply of Amgen’s medicines to patientsaround the world. Manufacturing therapies based on proteins found in the human body is a complex and highly specialized ac-tivity. From process development and clinical manufacturing tofull-scale therapeutic protein production, Amgen has built one of the industry’s largest and most reliable operations. Amgen operates manufacturing facilities in California, Colorado, Ireland, Puerto Rico, Rhode Island, and the Netherlands.

Advancing science through strategic partnershipsWith more than 100 active collaborations and growing, Amgen seeks to jointly unlock the potential of the world’s best science by bringing together our collaborators’ innovation with Amgen’ssubstantial experience, capabilities, financial resources, and track record of success in pursuing breakthrough medicines that serves patients with serious illnesses. Amgen embraces a culture that rewards and fosters a collaborative mindset and has evolved our capabilities to enable the success of our strategic partnerships that start with aligning around a shared vision with our partner and ends with the seamless execution of the pro-gram plan that oftentimes includes joint execution of activities throughout the collaboration lifecycle.

Philanthropy that makes a positive differenceThe causes Amgen supports, through the Amgen Foundation and other channels, reflect the company’s efforts to elevate sci-ence, help patients, and improve lives.

The Amgen FoundationThe Amgen Foundation (www.amgen.com/citizenship/over-view.html) seeks to advance science education; improve patient access to quality care; and strengthen the communities where Amgen staff members live and work. To date, the Foundation has donated over $200 million in grants to local, regional, and inter-national nonprofit organizations that impact society in inspiring and innovative ways. It has also supported disaster relief efforts both domestically and internationally.

Amgen is inspiring and preparing the scientists of tomorrow through several signature science education programs, includ-ing Amgen Scholars, an eight-year, $34 million program for un-dergraduates; the Teach For America Amgen Fellows Program; the Amgen Bruce Wallace Biotechnology Lab Program; and the Amgen Award for Science Teaching Excellence.

Winner of the 2013 SIMB Industry Award for Discovery, Innovation, and Development in Industrial Microbiology and Biotechnology

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Jim ThomasVice President ResearchProcess & Product Development Amgen

Jim Thomas currently leads Amgen’s large molecule Process and Product Development (P&PD) organization within Research & Development. His responsibilities include the de-velopment and application of all process, analytical and formulation technologies used to manufacture both clinical and commercial large molecule products for Amgen. He began his biotechnology industry career at Genentech in 1983 as a scientist in Cell Culture R&D before joining the department of Molecular Biology at Immunex Corporation in 1990. At Immunex, Jim initiated the effort to produce recombinant proteins, including Enbrel®, using mammalian cells as the host cell system. As director of Cell Sciences and then vice president of Process Sciences, he oversaw investment in technologies that are the foundation for large scale processes used at Amgen to produce molecules including Vectibix® and Prolia®. Jim received his PhD from Purdue University and completed a post-doctoral fellowship at MIT in biochemistry, nutrition and cell physiology.

The award lecture for the 2013 SIMB Industry Award for Discovery, Innovation, and Development in Industrial Microbiology and Bio-technology will be presented on Monday, August 12 at 4:30 pm by Jim Thomas, vice president of Process and Product Development, Amgen. A plaque will be presented to Amgen at the evening banquet on Tuesday, August 13.

Dennis FentonCEOFenton & Associates, LLC

After receiving a BS in Biology from Manhattan College and a PHD from Rutgers in Microbi-ology I began my career at Pfizer working the fermentation and recovery of industrial en-zymes. Excited by the possibilities of developing new therapies through the use of recom-binant DNA technology and the charisma of George Rathman, Amgens founding CEO, I was recruited to join Amgen as one of its first employees. During my 25 years at Amgen I held numerous positions of increasing responsibility including the Vice presidencies of Research, Process Development, Manufacturing, Human Resources and Sales and Marketing. I retired from Amgen in 2007 as the Executive Vice President of Operations. While enjoying all the benefits of early retirement I remain involved in the Biotechnology industry by sitting on the board of four public companies, Kythera, Xenoport, Dendreon and Hospira, two private companies Napo and Genelux as well as the Keck Graduate institute.

The keynote address entitled " The Evolving Role of Applied Microbiology in the Biotechnology Industry" will be presented on Sun-day, August 11 at 5 pm by Dr. Dennis Fenton, at Fenton & Associates, LLC.

Featured speakers and awardees

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Douglas CameronCo-President and DirectorFirst Green Partners

Doug Cameron is Co-president and Director of First Green Partners, an early-stage invest-ment firm focused on companies with technology related to renewable and fossil carbon. Doug's career has spanned business, finance, and academia, including positions at Khosla Ventures, Piper Jaffray, Cargill, and the University of Wisconsin-Madison. In 2009, Doug was the recipient of the prestigious Raphael Katzen Award for his contributions in furthering the deployment and commercialization of biotechnology to produce fuels and chemicals from renewable resources.

Doug graduated from Duke University with a bachelor of science in engineering degree in biomedical engineering. He earned a Ph.D. in biochemical engineering from the Massachu-setts Institute of Technology. Prior to attending MIT, he was the fourth employee of Advanced Harvesting Systems, an agriculture start-up company backed by International Harvester.

He is a Fellow of the American Institute of Medical and Biological Engineering (AIMBE), a Fel-low of the Society of Industrial Microbiology and Biotechnology (SIMB), and a Fellow of the American Society for the Advancement of Science (AAAS). Doug is also a consulting profes-sor of chemical engineering at Stanford University.

The Annual Banquet lecture will be presented on Tuesday, August 13 at 7:00 pm by Doug Cameron, co-president and director of First Green Partners.

Charles Thom Award: Bill Bentley, University of Maryland, College ParkCharles Porter Award: Betty Elder, Louisiana State University-AlexandriaSIMB Fellow: Sir David Hopwood, John Innes CentreWaksman Teaching Award: Susan Bagley, Michigan Technological UniversityYoung Investigator Award: Yasuo Yoshikuni, Bio Architecture Lab

Congratulations to SIMB's 2013 award winners, who will be honored at the banquet held at the Annual Meeting in San Diego on Tuesday, August 13.

Featured speakers and awardees

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BTEC workshops offered in 2013In 2013, SIMB will continue its partnership with North Carolina State University’s Bio-manufacturing Training and Education Center (BTEC) to offer discount to SIMB mem-bers on BTEC professional development short courses.

Several tracks are featured including Biomanufacturing, Bioprocess Development, Bioprocess Engineering and Analytical Technologies.

In addition, special course offerings in 2013 include Navigating the European Regula-tory System and Process Architecture: Integrating the Process to Deliver Successful Facility Solutions.

Members should visit the SIMB website for a list of upcoming workshops in 2013 or to download the BTEC 2013 brochure. BTEC is located in Raleigh, North Carolina and is within driving distance of many east coast locations or via the Raleigh-Durham Inter-national Airport.

Discounts range from 20% to 50% depending on the work-shop and member field of employment.

www.simbhq.org/education/

Best Student Poster Presentation Awards

Students participating in the Best Stu-dent Poster Presentation competition will be judged onsite during the hours of presentation, either Sunday or Mon-day. Each 3-hour poster session will be divided into two 1-1/2 hour periods, depending upon topic.

Students are required to stand by their posters and be ready to discuss

their posters during the specified 1-1/2 hour time period in order to be eligible for the cash award.

Poster slots are limited and no-shows registered for the meeting will be disqualified from the competition and may not be invited to present in the future.

Winners will be notified either via

a phone message to the student’s hotel room or via text or voice message.

Charles Thom Award: Bill Bentley, University of Maryland, College ParkCharles Porter Award: Betty Elder, Louisiana State University-AlexandriaSIMB Fellow: Sir David Hopwood, John Innes CentreWaksman Teaching Award: Susan Bagley, Michigan Technological UniversityYoung Investigator Award: Yasuo Yoshikuni, Bio Architecture Lab

meet ings


Recent Advances in Fermentation Technology (RAFT 10)November 3 - 6, 2013Marriott Marco IslandMarco Island, FL

Web site: www.simbhq.org/raft

Contact SIMBSponsorship [email protected]

Exhibits [email protected]

[email protected]

Dates and DeadlinesJuly 2013: Registration and housing open

September 9, 2013: Oral and contributed paper abstracts due

September 15, 2013: Poster abstracts due

Call for Papers and PostersAbstract submission is OPEN: http://sim.confex.com/sim/raft10/cfp.cgi.

Poster presentersSubmit your final abstract no later than September 15, 2013. The RAFT Poster Session will be held Monday evening, November 4. All posters displayed must have one author available during the pre-scribed time period to discuss the poster. In addition to invited papers, a number

of contributed abstracts will be accepted for oral presentations. Oral presenters should plan to upload their presentations to the conference website shortly before or just after conclusion of the conference. SIMB will send information via email. Presentations will be viewable only to RAFT 10 attendees via password.

IMPORTANT: You will be notified by email of acceptance of your poster abstract. All accepted Poster Presenters should be reg-istered and paid in full by the early bird deadline of October 3, 2013.

Sponsors

meet ings


Program TopicsAdvances in microbial expressionConveners: M. DeLisa, Cornell University and G. Barnard, Lilly and Co.

Advancements in the tools for adoption of Quality by Design: DoE and PATConveners: J. McCool, Lonza and R. Dominguez, Green Biologics

Building for the future – educating fermentation scientistsConvener: T. Davies, Green Biologics

Poster Session/receptionConveners: A. Mohagheghi, NREL and C. Dellomonaco, USA DuPont

Novel process and reactor designConveners: D. Laidlaw, Kuhner and M.C. Flickinger, North Carolina State University

From lab to market: Overcoming challenges to commercialization of bioprocessesConvener: S. VanDien, Genomatica

Process excellence and high quality manufacturingConveners: T. Rau, Lilly and Co. and Stuart Stooks, Novozymes

VenueMarriott Marco Island400 S. Collier BlvdMarco Island, FL 34145

Housing opens in July. Room rate: $209 including guest room internet.

The Marriott Marco Island Resort Golf Club and Spa allows you to kick off your shoes and explore paradise, now celebrating the completion of a $225 mil-lion renovation and redesign. This one-of-a-kind, acclaimed resort was recently voted onto the Conde Nast Traveler Read-ers’ Choice Top 100 list of large resorts on the U.S. mainland and onto the list of top 20 Florida Golf Resorts.

Nestled on three miles of pristine Southwest Florida beaches, the Marco Island Marriott is infused with Balinese beauty and offers on its property sev-eral renowned restaurants, champion-ship golf, a world-class spa and a wide range of activities and amenities as well as upscale shops for men and women, a spectacular free-form pool with views of the Florida Gulf, and completely re-designed and redecorated guest rooms.

For more information, visit www.marcoislandmarriott.com/.

SponsorshipProvide visibility to your organization and promote your brand. There are a variety of sponsorship benefit packages and opportunities for organizations of all sizes. Enhance your exposure and position your company as a leader in the industry with sponsorship. For more information, contact Chris Lowe ([email protected]).

ExhibitsExhibit prospectus available in June.

Prices: $1,100 SIMB corporate member, $1,400 noncorporate memberIncludes one 2' x 6' draped table, 2 chairs, company sign.Setup: Sunday, November 3Show dates: November 3-5

For information, contact Nancy Gorell ([email protected]).

AdvertisingAdvertising is available in the meeting program. For information on rates, con-tact Suzannah Citrenbaum ([email protected]).

Interested in advertising with SIMB?

SIMB offers several opportunities to advertise in both SIMB News and meeting programs. For information, please visit:

SIMB News: http://www.simbhq.org/docs/SNadrates2013_fillable.pdfMeeting programs: http://www.simbhq.org/docs/MPadrates2013_fillable.pdf

Questions? Contact Suzannah Citrenbaum ([email protected]).


book review

Book ReviewBy Elisabeth Elder

Topics in Ecological and Environmental MicrobiologyThomas M. Schmidt and Moselio Schaech-ter (editors)2012, xxi + 749ISBN 978-0-12-383878-0Academic Press/Elsevier, Walton, MA

The review of this book was initiated dur-ing a search for a textbook suitable for an environmental microbiology course. As a result, the breadth and depth of the material plus the ease with which students could grasp the materials were of particular importance. Scanning the initial pages of the book provides great insight into its quality and the depth of the contents. Common sections in the chapters include a list of abbreviations, defining statement, historical and/or a current perspective, introduction, and list of resources for further reading. The con-tents include a combination of materials derived from the Encyclopedia of Microbi-ology, third edition, plus additional mate-rials to broaden the scope and to provide recent developments.

The initial section, Microbial Ecology, covers general principles; microbial food webs; biofilms; microbial mats; horizontal gene transfer; algal blooms; environmen-tal viral pool; aeromicrobiology; and en-dophytic microbes. The combination of bacteria, fungi, viruses, and endophytes is indicative of the broad coverage. Inclu-sion of the picoeukaryotes, detected for only the past half-dozen years by culture-independent techniques, shows the care

that has been taken in updating and ex-panding the contents.

The second section, Metabolism and Behavior of Diverse Microbes, cov-ers methanogenesis; methanotrophy; microbial photosynthesis; regulation of carbon assimilation; microbial resistance to heavy metals; microbial adhesion; bac-terial bioluminescence; magnetotaxis; quorum sensing; and chemotaxis. An example of the excellent coverage in this section is the figure on central carbon metabolism (page 199) which interre-lates glycolysis, Entner-Doudoroff, pen-tose phosphate, and the TCA cycle. The presentation format and the clarity of the diagram should make these concepts easier for students to grasp. The combi-nation of the printed black and white ver-sion and the colorized web version make this resource very applicable in class and very easy to follow. The figure is supple-mented by a table with that shows en-zymatic differences between Escherichia coli and Bacillus subtilis. This combination will allow students to readily determine, and others to easily review, similarities and differences between these major pathways.

The third section, Microbial Habitats, covers acid environments; hot environ-ments; cold environments; dry environ-ments; marine habitats; high-pressure habitats; the deep subsurface; deep-sea hydrothermal vents; freshwater habitats; low-nutrient habitats; sediment habitats; and the rhizosphere. An example of the excellent coverage in this section is the table (page 357) which covers adapta-tions of organisms to dry environments. While such adaptations have not been in-vestigated for many organisms, the table provides a combination of different adap-tations with their functions and multiple

examples of representative organisms.The fourth section, Biogeochemi-

cal Cycles and their Consequences, cov-ers the nitrogen cycle; the phosphorous cycle; the sulfur cycle; cycling of some redox-active metals; and heavy metal pollutants. The organization of these ma-terials will make them applicable in envi-ronmental microbiology as well as other environmental science/ecology courses. The figure provided for the microbial ni-trogen cycle (page 484) should be very helpful for students in differentiating aerobic from anaerobic/oxygen-sensitive processes. The simplified sulfur cycle (page 524) is an excellent supplement to the text.

The last section, Biotechnological Topics, covers biodeterioration; biosen-sors; gnotiobiotic and axenic animals; microbial corrosion; petroleum microbi-ology; metal extraction and biomining; industrial water treatment; wastewater treatment of non-infectious hazards; drinking water; spacecraft associated microbes; and biological warfare. Based on my previous research and current teaching, the section on drinking water is of particular interest and is an example of the excellent information provided. The table on inactivation of microbes by chlorine-based disinfectants (page 696) includes a variety of compounds, a broad spectrum of microbes, as well as the impact of pH in an easily read, com-pact form. The impacts of temperature and cell injury are well documented in the text.

Overall this is an excellent book for inclusion in a professional library as well as for use in an upper level undergradu-ate or graduate course.

calendar


SIMB MeetingsFor further information on SIMB meetings, contact: SIMB, 3929 Old Lee Highway, Suite 92A, Fairfax, VA 22030-2421; T: 703-691-3357; F: 703-691-7991; E: [email protected]; W: www.simbhq.org.

August 11-15, 2013 2013 Annual Meeting and Exhibition

Sheraton San Diego San Diego, CA

November 3-6, 2013

RAFT 10 Marriott Marco Island Marco Island, FL

April 28-May 1, 2014

36th Symposium on Biotechnology for Fuels and Chemicals

Hilton Clearwater BeachClearwater, FL

July 20-24, 2014 SIMB Annual Meeting and Exhibition

Hyatt Regency St. LouisSt. Louis, MO

November 9-12, 2014

Recent Advances in Microbial Control

Marriott Union SquareSan Francisco, CA

Non-SIMB Meetings

July 21-25, 2013 5th Congress of European Microbiologists (FEMS 2013)

Congress Center Leipzig, Messe-Allee 1, Leipzig, Germany http://fems.kenes.com/

July 28-August 2, 2013

Archaea: Ecology, Metabolism and Molecular Biology

Renaissance Tuscany Il Ciocco Resort, Lucca (Barga), Italywww.grc.org/programs.aspx?year=2013&program=archaea

July 31-August 1, 2013

Biomass 2013: How the Advanced Bioindustry is Reshaping American Energy

Co-hosted by U.S. DOE's Bioenergy Technologies Office (BETO) and Advanced Biofuels Washington, D.C. Convention Centerwww1.eere.energy.gov/biomass/biomass_2013.html

August 28-30, 2013

Biofilm formation, its clinical impact and potential treatment

Stockholm, Swedenhttp://biofilmnobelconference.org

September 2-4, 2013

SGM Autumn 2013 Conference Sussex, UK www.sgm.ac.uk/en/events/conferences/index.cfm/autumn-2013-conference

September 8-13, 2013

Thermophiles 2013: 12th International Meeting

Regensburg, Germanywww.thermophiles2013.de


EUROBIOFILMS 2013 Ghent, Belgiumwww.eurobiofilms2013.ics.dk


ICAAC 2013: 53rd ICAAC Denver, Coloradowww.icaac.org

October 2-4, 2013 BioMicroWorld2013 V International Conference on Environmental, Industrial and Applied MicrobiologyMadrid, Spainwww.biomicroworld2013.org

October 23 - 25, 2013

2nd International Conference on Microbial Biodiversity

Turin, Italywww.biotagr.unipd.it/md2013/

calendar


Workshops and Short Courses

NOTE: SIMB has partnered with North Carolina State University’s Biomanufacturing Training and Education Center (BTEC) to offer discounted professional short courses to SIMB members.• SIMBmembersfromindustryreceivea20%discountoncourseregistration.• SIMBmembersfromacademiareceivea50%discountonregistration.To receive your discount, you must register for BTEC short courses through the SIMB website member login.

September 09 - 11, 2013

Metagenomics: Managing, Analysing and Visualising Data Course

European Bioinformatics Institute, Cambridge, United Kingdom www.ebi.ac.uk/training/course/metagenomics-course

October 28 - November 1, 2013

Advanced Course Metabolomics for Microbial Systems Biology

Delft, The Netherlandswww.bsdl-edu.bt.tudelft.nl//content/acMetabolomics.html

Varies BioBrainz Life Sciences – Courses in Bioinformatics and Biotechnology

Visit web site for details on courses offered: www.biobrainz.com/

Varies NSF International Visit web site for details on courses offered: www.nsf.org/cphe/.

Varies ASM - Teleconferences and Webinars

Visit web site for locations and details on courses offered.: www.asmaudio.org/

Varies Penn State – Food Microbiology Short Courses

Visit web site for details on courses offered: http://foodscience.psu.edu/workshops/food-microbiology

Varies Rutgers University – Food Safety Courses

Visit web site for details on courses offered: www.cpe.rutgers.edu/programs/food_science_food_safety.html

Varies Silliker Laboratories Call for details and a list of courses offered: 800-829-7879 or 708-957-7878.

Anyone wishing to publicize a meeting or have it included in the calendar is asked to send the information to: SIMB, 3929 Old Lee Hwy, Suite 92A Fairfax, VA 22030-2421; E: [email protected]. All entries will be listed on a space-available basis.

Do you judge Science Fairs?SIMB offers science fair certificates

Most Science Fairs have a section on microbiology and/or molecular biology, and many SIMB members assist local schools by judging in those categories. The SIMB Board of Directors authorized the Education Committee to provide

certificates to be presented to students in Science Fairs.

The criteria for receipt of a certificate are that an SIMB Member must be judging in the fair. Certificates will be available to the first, second, and third place winners if there are a suf-ficient number of entries. Email to the Education Committee the names, addresses of the schools, and judges’ names and addresses, and we will send the certificates already filled out for presentation. This will give the judges a second opportunity to interact with the students and encourage more interest in microbiology.

CONTACT Michael Flickinger ([email protected])

SIMB offers three levels of corporate membership. Bronze level at $700, provides the following benefits:

• Discount on exhibit space for your company.• One regular SIMB membership for a representative with subscriptions to SIMB News and JIMB.• Reduced rates on advertising in SIMB News, plus a free corporate profile in one issue.• Availability of the SIMB membership mailing list at a reduced cost (20% off).• Free announcements of contracts awarded, new products or publications & personnel changes listed in SIMB News.• Recognition in every issue of SIMB News and JIMB.• Company link and description included on the corporate membership page of SIMB’s website (50 words or less).• Discounts on job postings in SIMB’s online career center.

Gold - $1200, includes Bronze level benefits, plus • Two additional full exhibitor Annual Meeting registrations with banquet ticket (total 3). • One additional regular SIMB membership (total 2). • Company logo included on the corporate membership page of SIMB’s website. • Three free uses of the SIMB membership mailing list (and 20% discount on additional mailing lists).

Diamond - $2000, includes Gold level benefits, plus • One additional full exhibitor Annual Meeting registration with banquet ticket (total 4). • One free Exhibitor Showcase (10 minutes) at Annual Meeting. • One $500 credit toward an ad placement (Ad placement cost must be at least $500 before credit can be applied). • Company logo and link added to rolling display on SIMB’s homepage.

Method of payment (SIMB Fed ID: 35-6026-526) Check (Payable to SIMB) Charge: MC Visa AMEXCard #: Exp. date:Name on Card/Signature: Total amount enclosed: $

Our company will join SIMB as a corporate member in the following category:

Bronze, $700 Gold, $1200 Diamond, $2000

Name of Company:Company website:**send company description (all levels) & logo (Gold and Diamond Only) to [email protected]

Authorizing officer who is to receive all billing information:

Name ____________________________

Title _____________________________

Address __________________________

_________________________________

City, State, ZIP_____________________

Country___________________________

Tel _______________________________

Fax _______________________________

E-mail ____________________________

Company representative who will receive membership including publications:

Name ____________________________

Title _____________________________

Address __________________________

_________________________________

City, State, ZIP_____________________

Country___________________________

Tel _______________________________

Fax _______________________________

E-mail ____________________________

Additional company representative (Gold and Diamond Only):

Name ____________________________

Title _____________________________

Address __________________________

_________________________________

City, State, ZIP_____________________

Country___________________________

Tel _______________________________

Fax _______________________________

E-mail ____________________________

2013 SIMB Corporate Membership ApplicationSIMB • 3929 Old Lee Hwy, Ste 92A • Fairfax, VA 22030 • T: 703-691-3357 ext. 23 • F: 703-691-7991 • www.simhq.org

Please do not send me SIMB Information via e-mail. Please do not include me on any SIMB mailing lists.Please do not include my information in the SIMB onlinemembership directory

Please select a delivery method for JIMB.Note: SIMB News is available online only. Print copy delivery via postal service Print copy Online only access

Dedicated to the industrial application of microbiology and biotechnology

Corporate Member Benefits

•Three levels available

•Complimentary membership for corporate representative(s)

•Discounts on exhibit space, advertising, and mailing lists

•Company logo, description, and link to corporate member web site

•Free announcements of contracts awarded, new products, and personnel changes in SIMB News

•Recognition in every issue of SIMB News, JIMB, and on SIMB web site

www.simbhq.org

SIMB Career CenterSIMB has launched an improved career center.

With the career center, job seekers can search for jobs, post their resumes and set up automated alerts, notifying them when new jobs become available.

Employers can now post a job opening instantly, and are able to search through resumes to find qualified employees.

http://careers.simhq.org

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