summer 2015 cst merit research projects · summer 2015 cst merit research projects faculty name ......

Summer 2015 CST Merit Research Projects

Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department

Project title Project

Location

Project Description - the general area of

research involved in this project.

Important

selection criteria

Student

Majors

Hours

Per

Week

Allen

Nicholso

n (New

as of

2/19)

anichol@

temple.e

du

CST Biology Understanding

ribonuclease

mechanism and

function in gene

regulation

TU Main

Campus

We apply biochemical and molecular

genetic techniques to probe the mechanism

of ribonucleases and their function in gene

expression and RNA stability. Our primary

system is the bacterial cell, and we seek to

understand how bacterial cell motility,

biofilm formation, and response to stress are

regulated by ribonucleases.

Strong

performance in

biology and

chemistry courses

(including at least

one semester of

organic chemistry)

Biology and

Chemistry

coursework

through the

sophomore year.

Must have an

eagerness to learn

techniques, and be

prepared to go the

extra distance to

complete

occasionally

challenging

experiments

Biochemistr

y, Biology,

Chemistry

majors

~30 hrs

per

week

for ~10

weeks

Brent

Sewall

bjsewall

@temple.

edu

CST Biology Conservation

biology and

community ecology

TU Main

Campus

and off-

campus at

field sites

My lab is investigating multiple questions in

the fields of conservation biology and

community ecology, focusing on

understanding human drivers of change in

ecological systems and developing effective

Interest in the field

of conservation

biology or

community

ecology;

Biology,

Environment

al Science,

Mathematics

, or related

full-

time

but

hours

may be Darius

Balciuna

s

darius@t

emple.ed

u

CST Biology Genetic analysis of

cardiovascular

development and

regeneration in

zebrafish

TU Main

Campus

Please see the lab website

http://www.balciunaslab.com/

please take a look

at the lab website

http://www.balciun

aslab.com/researc

h-

Biology /

Biochemistr

y

at least

40

Erik

Cordes

(New as

of 2/19)

ecordes

@temple.

edu

CST Biology Molecular stress

response of deep-

sea corals

TU Main

Campus

Field studies and laboratory experiments

have revealed the effects of various

anthropogenic stressors (ocean

acidification, oil and dispersant exposure)

on deep-sea corals. The next step is to

identify the molecular markers that underlie

these responses. Once identified, these may

reveal the potential for corals to be resilient

Students who are

interested in

pursuing graduate

school in the

natural sciences,

ecology and

evolution.

Biology and

environment

al science

majors are

preferred,

but the

position

would be

20-30

3/6/2015 1


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Jacquelin

e Tanaka

jtanaka@

temple.e

du

CST Biology Investigating ion

channel mutations

associated with

complete color

blindness.

TU Main

Campus

My lab studies mutations in an ion channel

protein expressed in cone photoreceptors

that are associated with complete color-

blindness in humans and day-blindness in

dogs. The canine project is a collaboration

with U Penn Vet school faculty.

I would like to

recruit potential

MARC students.

The MARC U-

STAR program

provides mentoring

and financial

support for junior

and seniors

interested in PhD

programs in

biomedical

science. We would

like to recruit

younger students

to give them early

research

experience.

Biology,

biochemistry

, chemistry,

biophysics.

35

Jody Hey hey@tem

ple.edu

CST Biology Evolution and the

Human Genome

TU Main

Campus

Student's will work on questions about how

the human genome has evolved. Some of

the work may involve comparisons with Ape

genomes.

#1 Some computer

programming

experience.

planning a

major in the

life or health

sciences, or

in computer

science.

30

3/6/2015 2


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Karen

Palter

palter@te

mple.edu

CST Biology Investigating the

mechanism of

insulin resistance in

Type II diabetes

TU Main

Campus

Our laboratory has previously shown that

Drosophila melanogaster lacking a

functional sialic acid pathway display a

range of metabolic defects. We hypothesize

that the metabolic defects are a result of

excess insulin secretion from the insulin

producing cells (IPC). We have generated

transgenic flies carrying an ectopic copy of

the sialic acid synthase gene (SAS) under a

Dilp2 (insulin promoter) that is active only in

IPC cells. Fly strains were generated that

have this transgene in a SAS2d/2d

background (null for SAS) and therefore will

express the sialic acid synthase only in IPC

cells. All transgenic flies are male sterile

and all exhibit defects in locomotor activity,

as did the original SAS mutant strain.

However, all rescued strains no longer

exhibit the metabolic defects characteristic

of the SAS mutant strain, strongly

suggesting that such defects were due to

loss of sialic acid directly in the IPC cells.

We have demonstrated that one target of

sialylation (the addition of the terminal sugar

to glycoproteins) is a potassium channel in

the nervous system. We propose that the

result of excess insulin secretion from

insulin producing cells (IPC) were due to

Motivation and

interest in

research. Biology

2112

Biochemistr

y or Biology

35

3/6/2015 3


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Rachel

Spigler

tuf10949

@temple.

edu

CST Biology Floral trait variation

in a native biennial

plant, Sabatia

angularis

TU Main

Campus

Flowering plants display an amazing

diversity of floral forms, with adaptations

that enable them to attract pollinators and, in

cases when pollinators are scarce, self-

pollinate. In a greenhouse study, we will be

examining traits related to pollinator

attraction and the ability to self-pollinate in a

native biennial, Sabatia angularis. In

addition, we will be conducting an

experiment involving changes in resource

availability and pollinations to evaluate the

factors that influence floral trait expression.

dedicated and

responsible an

interest in plant

ecology and/or

evolutionary

biology -

Introduction to

Biology I (BIO 1111

or 1911) --There

will be

opportunities to

participate in field

work as well as

laboratory work

(DNA extraction,

PCR).

Biology,

Environment

al Science,

Natural

Science

20-40

Rob

Kulathina

l

robkulathi

nal@tem

ple.edu

CST Biology Genomics of

speciation

TU Main

Campus

Is speciation driven by genes involved in

reproduction? In this project, the student

will: 1) identify genes under selection using

evolutionary genomic approaches and/or 2)

knock-down those genes using ready-made

RNAi lines via our high-throughput

behavioral arenas. The student will be

trained by an active team of undergraduate

and doctoral students who are already

applying these powerful approaches using

Drosophila.

Determination,

curiosity, and

computationally-

inclined

Biology,

Computer

Science

30

Robert

Sanders

robert.sa

nders@te

mple.edu

CST Biology Mixotrophy -

photosynthetic

aquatic microalgae

feeding on bacteria

TU Main

Campus

There are numerous species of

phytoplankton that ingest food particles in

addition to photosynthesizing for their

nutrition. The effect of temperature and/or

UV radiation on the process will be

investigated.

Interest in project

with commitment to

complete most of it

over the summer.

Biology 1111 or

1911

Biology,

Environment

al Science

~ 30

hours

3/6/2015 4


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Daniel

Strongin

dstrongi

@temple.

edu

CST Chemistry Reactivity of Pyrite

and Acid Mine

Drainage

TU Main

Campus

The iron sulfide, pyrite, is found at active

and abandoned coal mining sites. Its

decomposition in the environment leads to

acid mine drainage (sulfuric acid generation)

which is a significant problems for coal

mining companies and the surrounding

environment. The goal of the project is to

look into strategies to suppress the

oxidation of pyrite and the resulting acid

generation.

Motivation

Academic

performance -

Introductory

Chemistry Courses

with Laboratory.

Chemistry

ESS

25

Eric

Borguet

eborguet

@temple.

edu

CST Chemistry Combining Photons,

Electrons and

Nanoparticles for

Plasmonic Sensing

and Catalysis

TU Main

Campus

Students will develop and use nanoscale

plasmonic materials for rapid, high

sensitivity detection of biological and

chemical agents, as well as catalytic

conversion. They will learn to use a variety

of analytical techniques such as

spectroscopy, Atomic Force Microscopy

http://www.temple.edu/borguet/index.html

Interest, curiosity

and persistence -

Undergraduate

researchers in my

group typically

present at local,

regional and even

national

conferences. Many

have been co-

authors on

publications.

Chemistry,

Physics

35

hours

Graham

Doberein

er

dob@tem

ple.edu

CST Chemistry Exploring the

influence of Lewis

Acids on

Organometallic

Compounds

TU Main

Campus

Organometallic complexes, which feature

metal-carbon bonds, underpin key catalytic

reactions in chemical industry. This project

will explore the synthesis of new complexes

using air-free technique, and investigate the

reactivity of these complexes in new

chemical reactions.

Prior classroom

laboratory

experience

(General

Chemistry, and

preferably Organic

Chemistry).

Chemistry 35

3/6/2015 5


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Katherine

Willets

kwillets@

temple.e

du

CST Chemistry Fabricating noble

metal nanoparticle

arrays for

applications in

molecular

plasmonics

TU Main

Campus

In this project, students will fabricate

nanodisk and nanohole arrays for

applications in plasmonics and

electrochemistry. For the nanodisk arrays,

block copolymers consisting of polystyrene

and polymethylmethacrylate (PS-b-PMMA)

are spun coat onto substrates and allowed

to self-assemble such that the sample yields

PMMA cylinders in a PS background. Next,

the PMMA is removed and metal is

deposited into the remaining holes in the PS

mask. Once the PS is removed, an array of

nanodisks remain behind. For nanohole

arrays, PS nanospheres self-assemble into

a hexagonal closed packed array on a

substrate. The nanospheres are reduced in

size via reactive ion etching, then metal is

desposited over the PS nanosphere mask.

Once the PS is removed, an array of holes

in a metal film will remain behind. Students

will learn a variety of fabrication (reactive

ion etching, metal deposition) techniques as

well as characterization techniques such as

atomic force microscopy and electron

microscopy.

Patient and self-

motivated. At least

two lab courses.

Chemistry 40

3/6/2015 6


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Scott

Sieburth

scott.sieb

urth@te

mple.edu

CST chemistry Simple Methods for

Complex Molecules

TU Main

Campus

make new molecules, purify them, shine

light on them, see if we make something

great. Learn to use a nuclear magnetic

resonance (NMR) spectrometer!

interest, ability and

willingness to

think, self-

motivated. organic

chemistry would be

appropriated - A

great set of

motivated graduate

and undergraduate

co-workers. The

goal is to make you

an independent

researcher ASAP,

have you do

something NEW

(e.g., research)

and get your name

on a publication.

need some

science -

this is a

laboratory

effort

must

be self-

motivat

ed

William

Wuest

wwuest@

temple.e

du

CST Chemistry Synthesis of Natural

Product-Inspired

Molecules to Perturb

Bacterial Biofilms

TU Main

Campus

Bacteria form complex communities known

as biofilms to protect themselves from

environmental stresses like antibiotics

proving troublesome to multiple factions of

society. Biofilms affect human health

(infections, dental plaque) and commercial

interests (oil industry, water purification,

shipping, residential) culminating in over

$60M in costs and over 100,000 deaths ,

therefore, any discoveries that inhibit or kill

these communities would be of great

interest to society. Students will perform

interdisciplenary research combining

synthetic organic chemistry, biochemistry,

and microbiology in an effort to thwart

bacterial biofilms.

Grades and

research interest

Biochemistr

y,

Chemistry,

Neuroscienc

e

During

Semest

er - 12-

15;

During

Summe

r - 40

3/6/2015 7


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Bo Ji boji@tem

ple.edu

CST CIS Software-Defined

Cellular Networks

TU Main

Campus

The purpose of this project is to develop and

implement resource allocation mechanisms

in software defined radio access networks.

For this project, participants will be exposed

to the basics of cellular networks (such as

4G LTE and WiMAX systems) and software

defined networks. This is a multi-faceted

project with both theoretical and systems

aspects suitable for students with different

background and interests. Participants with

a theoretical interests will be provided

projects such as algorithm design and

performance analysis. Participants

interested in system research can explore

system-level simulations in open source

simulators such as LTE-Sim and Open Air

Interface, or potentially build experimental

platform and implement the developed

resource allocation mechanisms.

Self-motivated.

Backgrounds in

networking, control

or math.

Computer

Science

Electrical

Engineering

30

Justin Y.

Shi

shi@tem

ple.edu

CST CIS Rapid 3D

Stereoscopic Scene

Creation

TU Main

Campus

This project is to study the use of Google

Sketchup and Open Source Unity3D

software to create 3D stereoscopic scenes

quickly for human motion studies.

Basic

understanding of

programming.

Experiences in

Sketchup and

Unity3D are a plus.

Basic programming

courses, such as

CIS1068 or

CIS1052.

CS, IST,

Digital

Media

15

hours/

week

3/6/2015 8


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Krishna

Kant

(New as

of 3/6)

kkant@te

mple.edu

CST CIS Reliability prediction

of large scale

storage systems

TU Main

Campus

This project involves analysis of data

collected from storage systems and its

characterization relative to the observed

errors that can be used for reliability

prediction of the storage system.

The project would

need good

programming

skills, exposure to

discrete-even

simulation, and

basic background

in computer

networks.

300

hours

over

the

summe

r

Krishna

Kant

(New as

of 3/6)

kkant@te

mple.edu

CST CIS Collaborative

caching in content

centric networks

TU Main

Campus

The project will involve simulation study of a

computer network designed for distributing

content such as audio/video that is widely

accessed and may have varying levels of

demands from different parts of the network.

The purpose of the simulation is to study

various collaborative policies for caching the

content.

The project would

need good

programming

skills, exposure to

discrete-even

simulation, and

basic background

in computer

networks.

300

hours

over

the

summe

r

3/6/2015 9


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Slobodan

Vucetic

vucetic@

temple.e

du

CST CIS Data Science TU Main

Campus

Scientific and technological advances have

allowed us to collect massive amounts of

diverse types of data. There is an increasing

recognition that data created by scientists,

mobile apps, internet, social media,

crowdsourcing, healthcare could be

translated into valuable insights. A data

scientist is a person who has the skills,

knowledge, and ability to extract actionable

knowledge from the data -- either for the

good of society, advancement of science, or

profit in business. This project will be

custom-made to suit the background and

interest of a student and give an opportunity

to get an expertise in all aspects of data

science including collecting, accessing, and

processing large and complex data,

applying methods from machine learning

and statistics to analyze data, and

presenting the data and analytic insights

through modern visualization techniques.

Some

programming

experience, good

math background -

Programming in

any language

(Python, Java, C,

Matlab) Calculus 1

Any CST

major might

find this

project

valuable

37.5

hours

during

8

weeks

3/6/2015 10


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Xiaojiang

Du (New

as of

2/19)

xjdu@te

mple.edu

CST CIS Security and Privacy

Issues of Android

Phones

TU Main

Campus

In this project, the undergraduate student

will work with Dr. Du and his Ph.D. students

on Security and Privacy Issues of Android

Phones. First we will identify possible

attacks on Android Phones security and

privacy. Second, we will design effective

security schemes to defend these attacks.

Third, we will implement the security

schemes in real Android Phones. Fourth, we

will perform real experiments on Android

Phones to evaluate the effectiveness of the

designed security schemes. If the

experimental results are good, we will write

research papers based on the design and

experiments, and submit to ACM/IEEE

conferences.

Good programming

skills High GPA

Sound math

background

CIS, Math 20

Zoran

Obradovi

c (New

as of

2/19)

zoran.obr

adovic@t

emple.ed

u

CST CIS - Data

Analytics

Center,

Computer and

Information

Science,

Statistics

Predictive analytics

in big data

TU Main

Campus

Predicting the system behaviors by

analyzing big data. Applications include

social networks, medicine, climate and

environment. For more details see

http://www.dabi.temple.edu/~zoran/

Interdisciplinary

interests; Self-

motivation;

Problem solving

skills; Some

programming

experience in any

language -the

projects will be

tailored to the

students' level of

preparation.

Computer

Science,

Statistics,

Physics,

Biology,

Chemistry,

Pharmacy,

Geology,

Environment

al Science

20-40

3/6/2015 11


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Sujith

Ravi

(New as

of 2/27)

sravi@te

mple.edu

CST Earth &

Environmenta

l Sciences

Belowground

responses to climate

change: Root

imaging and

analysis

TU Main

Campus

Belowground processes such as root

dynamics can alter nutrient and water cycles

and impact the response of terrestrial

ecosystems to changing climate and

disturbance regimes. Despite the relevance

of belowground processes, studies

addressing the response of fine roots to

changing environmental conditions are rare,

mostly due to the difficulties in quantifying

root dynamics (production, growth and

longevity) by non-destructive methods. This

project will investigate the belowground

responses of plants to simulated changes in

climate, in particular warming and droughts.

We will analyze a time series of below

ground (root) images from a simulated

climate change experiment (combination of

warming and drought), collected using the

unique minirhizotron root imaging system.

This technique will enable us to observe

root growth over time and trace single roots

in the course of their development. The

methods involve computer-based image

analysis using the open source software

application – Rootfly – and statistical

techniques for simultaneous calculation of

fine root production, length, mortality and

turnover.

interest in the

project/research,

critical thinking,

quantitative ability -

Basic statistics,

interest in image

processing, mostly

computer-based

project

Biology,

Computer

science,

Environment

al Sciences

30 - 40

hours

3/6/2015 12


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Sujith

Ravi

(New as

of 2/27)

sravi@te

mple.edu

CST Earth &

Environmenta

l Sciences

Environmental

impacts of large-

scale biochar

application

TU Main

Campus

Agricultural production is a major contributor

to anthropogenic greenhouse gas emissions

and associated global warming. In this

regard, novel carbon sequestration

strategies in agricultural areas such as large-

scale biochar (carbon-rich porous substance

produced by thermal decomposition of

biomass under oxygen-limited conditions)

application may provide sustainable

pathways to increase the terrestrial storage

of carbon in agricultural areas along with

increasing crop production. Biochar has a

long residence time in the soil (1000s of

years). Hence, understanding the soil

properties affected by biochar addition

needs to be investigated to identify the

tradeoffs and synergies. Even though

several studies have investigated the

impacts of biochar application on a variety

of soil properties, very few studies have

investigated the impacts on soil erosion, in

particular on dust emissions and

subsequent impacts on air quality. Emission

of fine biochar particles may result from two

mechanisms, (a) very fine biochar particles

are entrained into the air stream when the

wind velocity exceeds the threshold, and (b)

fine biochar particles are produced due to

abrasion by quartz grains. As fine biochar

particles effectively adsorb/trap

interest in

research, critical

thinking

Geology,

Environment

al Sciences,

Environment

al

Engineering

30

hours

3/6/2015 13


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Laura

Toran

ltoran@te

mple.edu

CST EES Stormwater

monitoring

Campus

and

suburban

streams

Students will help conduct research on how

stormwater affects streams and how to

control stormwater. We evaluate effects

using data loggers. Field work and

computer analysis is involved.

Commitment to

protecting the

environment and

plan to follow up

with relevant

coursework -

Should like working

outside, but also

working with

computers as the

data collection is

done use loggers

and lots of data is

generated.

Geology and

Environment

al Science

would

consider

Computer

Science for

some

aspects of

the project

20-30

3/6/2015 14


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Ilya

Buynevic

h (New

as of

2/19)

coast@te

mple.edu

CST EES/Geology Neoichnology:

Imaging of Animal

Traces in Coastal

Sediments

TU Main

Campus

Analysis of modern structures (casts) and

georadar images of several large organisms

(crustaceans, reptiles) that produce

bioturbation structures (burrows, nests) in

coastal settings (beaches and dunes). The

findings will have implications to

geomorphology, sedimentology/stratigraphy,

petroleum geology (macroporosity),

geoarchaeology, geoforensics, and

conservation (e.g., sea turtle nests).

Ability to work both

independently and

as part of a

research team,

with a possibility of

field data

collection.

Computer skills

(especially

MATLAB preferred,

but not required).

Introductory

Biology and /or

Geology courses

Opportunity for

presentation of

results at a

national Geological

Society of America

Conference

(Baltimore -

November 2015)

Geology,

Environment

al Science,

Biology,

Civil

Engineering

25-30

Sudhir

Kumar

s.kumar

@temple.

edu

CST iGEM and

Biology

Genomics,

Medicine, and

Evolution (computer

based)

TU Main

Campus

Students will carry out biological and

biomedical research using computers with

emphasis on DNA data analysis. Biomedical

questions will be focused on Genome

Medicine. Biological questions will be on

building the tree of life. Depending on the

student's background, you may conduct

primary data analysis research and/or assist

in developing new methods, software, and

databases. See igem.temple.edu and

www.kumarlab.net

Freshmen and

sophomores with

interest in biology,

medicine, or

computers. No

requirements, as

the projects will be

tailored to the

students' level of

preparation.

Biology,

Computers,

Physics,

Anthropolog

y,

Pharmacy,

Chemistry

20-40

hours/

week

during

the

summe

r

3/6/2015 15


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Sudhir

Kumar

s.kumar

@temple.

edu

CST Institute for

Genomics

and

Evolutionary

Medicine

Genomic Medicine

and Tree of Life

TU Main

Campus

Evolutionary analytics of mutations,

genomes, and species is the primary focus

of my research group. We use integrative

and comparative approaches to make

fundamental discoveries in the fields of

medicine, evolution and genomics. The

common theme of all our research is the use

of comparative analysis to reveal genome

differences that are outcomes of natural

selection on novel mutations arising in all

species during their propagation from

generation to generation and in an

individual’s lifetime. The resulting patterns

of conservation and divergence of our DNA

enables us to conduct research

investigations ranging from establishing the

tree of life scaled to time (TimeTree of Life)

and to forecasting disruptive mutations

found in personal germline and somatic

genomes (Phylomedicine). In these pursuits

of biological discoveries, we are also

developing new statistical methods and

computer algorithms to quickly analyze

large-scale datasets in these disciplines.

We also develop and disseminate many

high-impact software tools (MEGA and

myPEG) and databases/applications

(TimeTree and FlyExpress). See

www.kumarlab.net for a list of papers and

igem.temple.edu for our new institute

website.

Prefer freshmen or

sophomores

interested in

devoting multiple

years working in

our group so they

can carry out real

research and

development

projects, including

the writing of

research papers

and/or

development of

software and

database tools.

Successful

students will be

provided year-long

wage-payroll

positions to pursue

research. Interest

in doing computer-

based research; no

wet-lab or field

work. --Have a

look at our website

igem.temple.edu

and see how

Temple is

becoming a leader

in genomics.

Biology,

Computer

Science,

Chemistry,

Physics,

Biomedical

engineering,

and other

biology-

related

department

We

expect

30+

hours a

week

during

the

summe

r and

10+

hours

during

the

regular

semest

er.

3/6/2015 16


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Matthew

Stover

(New as

of 2/19)

mstover

@temple.

edu

CST Mathematics Discriminants of

integer polynomials

TU Main

Campus

This project will study discriminants of

polynomials with integer coefficients. For

quadratic polynomials, this is the familiar

expression b^2 - 4ac. It is a hard and

interesting problem in number theory to give

an explicit lower bound for the discirminant

of a monic polynomial that does not factor

into small polynomials (also with integer

coefficients). One such bound was given by

Odlyzko and Poitou many years ago, and it

is a very complicated expression involving

pi and Euler's constant and integrals of

functions with very bad behavior near the

origin. This project will use high-power

computing to explore these bounds in detail

for small degree and try to obtain new and

interesting bounds for discriminants of

polynomials. Students should know integral

calculus, have solid foundations in computer

programming, and an interest in learning

about parallel computation and other

methods.

Students should

know integral

calculus, have

solid foundations in

computer

programming, and

an interest in

learning about

parallel

computation and

other methods.

Math or CS 37.5

3/6/2015 17


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Yury

Grabovsk

y

yury@te

mple.edu

CST Mathematics Links between

effective elastic

tensors of pairs of

fiber-reinforced

composites with

common

microstructure

TU Main

Campus

Elastic properties of composite materials

depend both on the microstructure and

properties of constituent materials. This

project aims to investigate latter

dependence by characterizing those

transformations of elastic properties of

constituent materials that are preserved at

the level of the effective properties of

composites. In combination with results of

prior work of URP students these

transformations, called links, can provide a

wealth of information about composite

materials. Existing theory has provided a

largely automated way to compute all links

for the fiber-reinforced composites. The

final step in this process|casting the results

in a mathematically beautiful form

communicable to the world, can be done

only by a human being, since we do not

know how to describe "beautiful" to a

computer. The computational procedure is

neither too easy nor too difficult, providing

an ideal problem, where an undergraduate

student can learn a lot of new mathematics,

while contributing to the research in

theoretical materials science and applied

mathematics.

Understanding of

vector spaces and

linear operators as

in the Theoretical

Linear Algebra

course Math 3051 -

Math 3051 is

desired but not a

hard requirement --

This is a

mathematics

project, not a lab,

so the hours are

very flexible.

Any CST

major with

required

knowledge

20-40

depend

ing on

the

number

of

weeks

Adrienn

Ruzsinsz

ky

aruzsinsz

ky@temp

le.edu

CST Physics Electronic structure

of layered

semiconductors

TU Main

Campus

ground-state and/or excited state

calculations of layered semiconductors for

nano-electromechanical device industry and

photovoltaics

interest in

theoretical/comput

ational research,

good

computational

skills

Physics,

Chemistry

20

3/6/2015 18


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Ke Chen

(New as

of 2/19)

kchen@t

emple.ed

u

CST Physics Superconducting

devices for high

performance

sensors and circuits

TU Main

Campus

Superconductors are superior materials for

devices with phenomenal performance

compared to normal materials due to their

zero dc electric resistivity and other unique

quantum properties. This project will focus

on fabricating and characterizing MgB2 (an

amazing superconductor) devices for high-

speed circuits and high-sensitive magnetic

field sensors. These applications are the

current interest in defense, industrial, and

many other areas.

Skillful in carry out

experiments in a

lab. Familiar with

electronics and

material sciences.

Interested in

solving problems.

General Physics I

and II (either

calculus based or

not)

Physics,

Electric

engineering,

Chemistry

20

Xiaoxing

Xi

Xiaoxing

@temple.

edu

CST Physics Fabrication and

studies of

superconducting

thin films for device

applications

TU Main

Campus

We work mainly with superconducting thin

films for device applications at small and

large scales. For this purpose, films of

magnesium diboride (MgB2) and various

layered oxides are grown with different

deposition methods in our lab. The films are

characterized in terms of their transition

temperature, critical currents, surface

morphology, and performance under RF

conditions. The purpose of these studies is

to investigate the feasibility of these films for

the use in josephson junction based devices

as well as large scale applications, such as

RF cavities currently being employed in

particle accelerators.

Interested in

research, hard

working, aptitude

for careful

laboratory

research, fond of

problem solving,

motivated to learn,

basic

understanding of

physics

physics,

engineering

######

3/6/2015 19


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Marc A.

Ilies PhD

(New as

of 2/19)

mailies@

temple.e

du

School of

Pharmacy

Pharmaceutic

al Sciences

Synthesis and

characterization of

carbonic anhydrase

inhibitors and

activators

TU Health

Science

Campus

Carbonic anhydrase is a zinc

metalloenzyme involved in many

physiologic processes such as cellular

respiration and transport of CO2 from

metabolizing tissues to lungs, pH

homeostasis, gastric acid secretion, bone

remodelling gluconeogenesis, etc. It has 15

isozymes with different cellular localizations

and biochemical properties. Some of these

isozymes are over-expressed in various

disfunctions and diseases including

cancers. We are interested to generate

isozyme-selective inhibitors and activators

for carbonic anhydrase with high intrinsic

activity and in vivo efficacy.

background

(organic

chemistry), past

experience,

motivation

chemistry,

biochemistry

40

Ana

Gamero

gameroa

@temple.

edu

TUSM Biochemistry STAT2 Signaling in

Cancer

TU Health

Science

Campus

STAT2 is a transcription factor widely

recognized for its role in host defense

against microbial attack and inflammation.

Published work from my laboratory now

suggests that STAT2 is also implicated in

cancer development. We have evidence in

animal models of cancer that STAT2

functions to promote tumorigenesis. Based

on this exciting finding, the main objective of

my lab is determine the underlying

molecular mechanism by which STAT2 is

promoting cancer development.

Strong knowledge

of biological

concepts Self-

motivated and

willingness to work

hard Good

communication

skills Able to work

well with others

Biology,

Biochemistr

y

40-

45hour

s

3/6/2015 20


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Hong

Wang

hongw@t

emple.ed

u

TUSM Center for

Metabolic

Disease

Research

Homocysteine and

Cardiovascular

Disease

TU Health

Science

Campus

The objective of project is to study how

hyperhomocysteinemia (HHcy, is a medical

condition characterized by an abnormally

high level of homocysteine in the blood,

conventionally described as above 15

µmol/L.) causes atherosclerosis. Since

atherosclerosis is a pathological

characteriostics of cardiovascular disease,

which is the number one killer in the United

States and developed contries. HHcy is the

identified independent risk factor for CVD.

However, the unberlying mechnism is

unknown and ecffective therapeutis

approaches are not available. Our

laboraory is the leading laboratory in

hyperhomocysteinemia and cardiovascular

disease research. We have made significant

contribution in this field. We are the first to

report that hyperhomocysteinemia causes

atherosclerotic changes in cell culture and

mouse modles, and demonstrated essential

cellular and molecular mechinsms.

Motivation,

carefulness -

Students who

completed

sophomore year.

Biology 30

hours/

week

3/6/2015 21


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

John

Elrod

elrod@te

mple.edu

TUSM Center for

Translational

Medicine

Investigation of

candidate genes

identified by a

genome-wide, loss-

of-function screen of

cellular necrosis.

TU Health

Science

Campus

The goal of these studies is to follow up on a

large discovery-based screen and examine

key genes thought to play a role in necrotic

cell death. Programmed necrosis is central

to numerous human diseases and the

identification of new pathways is paramount

to designing new therapeutic strategies.

Students will examine candidate genes and

their role in death signaling using: cell

culture techniques, generation of stable cell

lines, viral gene modification, cell death

assays, and live-cell imaging. Students are

expected to actively participate in project

design, understand the literature pertinent to

the project, and complete experiments in a

well-controlled and timely fashion. All

project design and data interpretation will be

performed jointly with the PI. If significant

progress is made the student may be able to

submit an abstract or contribute as an

author on a published manuscript.

Commitment to

project beyond the

summer Work

ethic Previous lab

experience Self-

motivated

individual

Science or

Mathematics

40

Madesh

Muniswa

my

madeshm

@temple.

edu

TUSM Center for

Translational

Medicine

Uncovering the role

of bioenergetics in

cardiovascular

disease

TU Health

Science

Campus

This project will continue our lab's work on

discovering the identity of the mitochondrial

PTP "death pore" ( mitochondrial

permeability transition pore). In this project

students will use various techniques

including: confocal microscopy, cell culture,

western blotting, mini/maxi preps, and

microorganism transformations. Our goals

will be to continue refining our knowledge

about the PTP by determining its functional

regions and which proteins interact with it to

control its opening and closing.

Interested in a

scientific career --

No prior research

experience is

required. We only

ask that you have

an eagerness to

learn new

techniques.

Biology,

Biochemistr

y,

Biomedical

Engineering,

Bioengineeri

ng,

Chemistry,

Microbiology

,

Immunology

30-40

3/6/2015 22


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Sara

Jane

Ward

saraward

@temple.

edu

TUSM CSAR Cannabinoids,

Inflammation, and

CNS Injury

TU Health

Science

Campus

Research focuses on determining the role of

inflammation across a range of CNS

disorders, from stroke to substance abuse.

We take a behavioral and molecular

immunological approach to studying the role

of inflammation in CNS disorders and

testing the hypothesis that cannabinoid

based-treatments have a potential to reduce

this inflammation and therefore improve

behavioral outcomes.

Interest in

neuroscience/expe

rimental

psychology

Neuroscienc

e,

Psychology

Mahmut

Safak

msafak@

temple.e

du

TUSM Department of

Neuroscience

Investigation of the

regulatory roles of

JC virus

Agnoprotein in viral

life cycle

TU Health

Science

Campus

Agnoprotein is one of the important

regulatory proteins of the human

polyomavirus, JC virus. It is a relatively

small and basic protein. we have recently

demonstrated that it forms highly stable

dimers and oligomers. It exhibits the ability

to be released from the infected cells. The

implications of this release unknown. It

Student with a

good work ethics

Biology,

Chemistry

Biochemistr

y

Neuroscienc

e

40h per

week

3/6/2015 23


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Richard

T.

Pomeran

tz

richard.p

omerantz

@temple.

edu

TUSM Fels Institute

for Cancer

Research

Mechanisms and

Regulation of

Mammalian DNA

Repair

TU Health

Science

Campus

Project 1: Cloning and purifying a domain of

human DNA Polymerase Theta. This

polymerase is involved in error-prone DNA

repair and is needed for the survival of cells

deficient in important DNA repair genes

such as BRCA1 and BRCA2.

Overexpression of polymerase theta

corresponds to a poor clinical outcome for

breast cancer patients. We aim to

understand the functions of this polymerase

using biochemical methods. Project 2:

High-throughput drug screening for

compounds that specifically kill cancer cells

deficient in BRCA1 or BRCA2 tumor

suppressor proteins. We are screening for

small-molecules that inhibit RAD52 and

polymerase theta which have been shown to

promote the survival of cancers deficient in

BRCA proteins. We aim to identify specific

drug inhibitors of RAD52 and polymerase

theta for potential clinical applications.

Intelligent, hard-

working,

independent,

passionate about

science and

research. - General

Biology, perhaps

Chemistry --

Successful

summer research

is likely to be

published in peer

reviewed journals.

Biochemistr

y, Biology,

or Chemistry

40

hours/

week

3/6/2015 24


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Nora

Engel

(New as

of 2/19)

noraenge

l@temple

.edu

TUSM Fels

Institute/Bioch

emistry

Analysis of gene

regulatory elements

in an imprinted

region related to

cancer

TU Health

Science

Campus

The Kcnq1 domain is comprised of at least 9

imprinted genes that have different patterns

of expression during mouse embryogenesis.

To completely understand how these

patterns are established and maintained, we

need to identify tissue-specific enhancers

and silencers. This project has the goal of

identifying and validating candidate DNA

sequences that fulfill the role of directing

tissue-specific expression during

development and that can be affected by

environmental factors, leading to disease.

We will be focusing on CDKN1C, a cell

cycle inhibitor that if often altered in cancer.

Several candidate enhancers and insulators

will be tested in tissue culture with reporter

assays, and their endogenous methylation

status will be assessed in mouse embryonic

tissues.

Previous lab

experience &

Genetics course

We work with mice,

with mouse

embryonic stem

cells, and do a

number of

molecular biology

techniques

routinely, such as

PCR,

pyrosequencing,

DNA methylation

analyses,

chromatin

immunoprecipitatio

ns, etc. All of these

technologies are

combined to

understand how

the genome is

regulated.

Biology at least

20

Brad

Rothberg

rothberg

@temple.

edu

TUSM Medical

Genetics and

Molecular

Biochemistry

Molecular

Mechanisms of

Fragile X Syndrome

TU Health

Science

Campus

Fragile X syndrome (FXS) is the most

common genetic disorder linked to

intellectual disability and autism. This

project is focused on determining the crystal

structure of Fragile X protein (FMRP), which

is lost or damaged in individuals with FXS.

Most important

selection criteria

are good

organizational

skills and interest

in learning about

protein structure.

Biology,

Biochemistr

y, or

Neuroscienc

e majors are

preferred.

30-35

hrs per

week.

3/6/2015 25


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Glenn S.

Gerhard

tuf81289

@temple.

edu

TUSM Medical

Genetics and

Molecular

Biochemistry

A new thyroid

cancer gene.

TU Health

Science

Campus

Cellular hydrogen peroxide is associated

with cancer, although the source(s) and

precise role remains unclear. We have

identified a candidate cancer gene in a

family with a highly penetrant dominant form

of papillary (non-medullary) thyroid cancer.

A predicted damaging mutation in a

transmembrane domain segregated with

papillary thyroid cancer in the family. We

hypothesize that the transmembrane

mutation causes mis-localization of the

protein to the cytoplasm with inappropriate

intra-cellular production of hydrogen

peroxide that subsequently leads to the

development of papillary thyroid cancer in

carriers of the mutation. Our aims are to

determine whether the mutation causes

oxidative stress in vitro and thyroid cancer in

zebrafish and mice.

Team oriented

Prior laboratory

experience

Science GPA --If

you work with

zebrafish, be

prepared to get

wet!

Biochemistr

y Biology

Chemistry

40

3/6/2015 26


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Parkson

Chong

pchong02

@temple.

edu

TUSM Medical

Genetics and

Molecular

Biochemistry

Novel Membranes

for Targeted Drug

Delivery/Controlled

Release and Other

Technological

Applications Such

As Artificial

Photosynthesis

TU Health

Science

Campus

Project 1: Archaeal bipolar tetraether

liposomes (BTL) are remarkably stable and

robust biomaterials, holding great promise

for technological applications. They can be

used as targeted carriers, slow-release drug

carriers, biosensors, microbubbles for

imaging and diagnosis, sterilized storage

devices, and coating materials. The goals of

this research are: (1) to gain a deeper

molecular understanding of the structure-

activity relationship of BTL liposomes in

order to improve their usage as biomaterials

and explore their possible new applications,

and (2) to design and fabricate liposomes (i)

for targeting phosphatidylserine- and

phosphatidylethanolamine-rich areas in

cells and (ii) as thermosensitive liposomes

for controlled drug release. Project 2: The

main objective of this research is to

fabricate a highly efficient and durable,

membrane-based artificial photosynthesis

device using novel lipids and enzymes from

thermoacidophiles. The system would be

capable of converting sunlight, CO2 and

water into carbohydrates for the production

of biofuels such as ethanol. The innovation

of this research lies in (i) the use of archaeal

bipolar tetraether lipids in the reconstitution

of bacteriorhodopsin (BR)/ATP synthase

having passion in

science and

technology; eager

to learn new things;

willing to devote a

significant amount

of time to the lab

work; - general

chemistry--

required;

advanced courses,

including but not

limited to organic

chemistry and

physical chemistry,

would be helpful. --

This is a

multidisciplinary

project, particularly

suitable for

students who plan

to attend graduate

school in the near

future.

Chemistry,

Biology,

Physics,

Bioengineeri

ng

25-30

hours

per

week

3/6/2015 27


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Bettina

Buttaro

bbuttaro

@temple.

edu

TUSM Microbiology

and

Immunology

Enterococcal

pheromone

inducible

conjugative

plasmids as

virulence factors

and disseminators

of antibiotic

resistance genes

TU Health

Science

Campus

Pheromone inducible conjugative plasmids,

such as pCF10, play a central role in the

ability of Enterococcal faecalis to cause

disease. They encode antibiotic resistance

and virulence genes in addition to mediating

transfer of chromosomal determinants

between strains. These plasmids also

contribute to the ability of the bacteria to

cause disease and to spread antibiotic

resistance genes to other species and

genera of bacteria. The goal of the

chemistry/biochemisty projects is to

characterize the molecular mechanisms that

allow the bacteria to vary the copy number

of the plasmids in response to oxidative

stress. The goal of the biology projects is to

understand how the plasmid transfers

antibiotic resistance genes to bacteria in

mixed species biofilms.

desire to learn to

design and perform

experiments

independently

under guidance --

Students are given

a scientific

question to answer

experimentally.

They will be

mentored in

designing their

experiments,

performing them

and interpret their

data.

chemistry/bi

ochemistry

and biology

It can

vary -

general

ly the

300 hrs

should

be

comple

ted M-F

betwee

n the

hours

of 8:30-

5:30

Stefania

Gallucci

gallucci

@temple.

edu

TUSM Microbiology-

Immunology

Regulation of Type I

Interferons in

Autoimmunity

TU Health

Science

Campus

The project includes studies of cellular

immunology and molecular biology of signal

transduction of cytokines involved in the

pathogenesis of an autoimmune disease,

Systemic Lupus Erythematosus. The goal of

the project is to test novel biologics to be

used in the therapy of autoimmune

diseases.

Strong motivation

to learn and hard

working.

Biology_Pre

med

at least

40

Bassel E

Sawaya

sawaya

@temple.

edu

TUSM Neurology/Fel

s Institute

Can HIV-1 proteins

promote premature

brain aging

TU Health

Science

Campus

Patients infected with HIV-1 suffer from

learning and memory deficit. The

mechanisms leading to these alterations

remain unknown. We are in the process of

deciphering these mechanisms

Ask, Learn, Enjoy, All 15hrs/

week

3/6/2015 28


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Prasun

K. Datta

(New as

of 2/19)

dattapk@

temple.e

du

TUSM Neuroscience Regulation of

glutamate

transporter EAAT2

in the context of

NeuroAIDS

TU Health

Science

Campus

Research focuses on determining the role of

HIV-1, cytokines and drugs of abuse in the

regulation of glutamate transporter

expression in astrocytes, microglia and

macrophages. If significant progress is

made by the student then he/she will be

allowed to submit an abstract to a national

meeting or submit a manuscript for

publication as a contributing author.

Selection criteria

are good

organizational

skills, interest in

learning and

hardworking.

Prefer prior

experience in

research

Prefer to

have

students

with

neuroscienc

e,

biochemistry

or biology

major.

At least

30 hrs

per

week

Xuebin

Qin

xuebin.qi

n@templ

e.edu

TUSM Neuroscience Applying a novel cell

knockout model for

CNS diseases

TU Health

Science

Campus

Conditional and targeted cell ablation is fast

becoming a powerful approach for studying

cellular functions and tissue regeneration in

vivo. Taking advantage of the exclusive IL Y

interaction with hCD59, I have developed a

novel tool to investigate the role of specific

cells in the pathogenesis of human

diseases. IL Y administration to the

transgenic mice expressing hCD59 in

specific cells can be used to generate this

cell ablation model, in which IL Y specifically

damages hCD59-expressing cells in the

mice. We can utilize this concept to develop

a new cell ablation model to study the

functions of different cell types under

physiologic and patho-physiologic

conditions including cell differentiation and

tissue development in many species. I have

established multiple collaborations with

Scientists in USA to further utilize this

approach for their research projects in many

species.

Working hard -

Genetics Cell

biology

Genetics or

molecular

biology

300

hours

over

the

summe

r

3/6/2015 29


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Adil I.

Khan

PhD

adil.khan

@temple.

edu

TUSM Pathology

and

Laboratory

Medicine

Role of adhesion

molecules in acute

inflammation.

TU Health

Science

Campus

In Vitro and in vivo assays would be used to

investigate the role of adhesion molecules in

models of acute inflammation.

Good writing skills;

be able to work

independently. the

work may involve a

mouse models, so

should be willing to

work with live

animals.

Any science

major.

20-40

hours/

week

over a

1-2

month

period

3/6/2015 30


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Wenzhe

Ho

wenzheh

o@templ

e.edu

TUSM Pathology

and

Laboratory

Medicine

Exoosme in

Methamphetamine

and HIV-associated

Neurodegeneration

TU Health

Science

Campus

The proposed studies will reveal previous

unidentified mechanisms by which METH

and/or HIV compromise the BBB innate

immunity, providing a favorable micro-

environment for HIV neuroinvasion.

Prefer to have

students with

biology major,

having a great

interest in research

(with or without

experience,

although research

experience is

preferred).

Students should

have attributes of

paying attention to

details, being a

good listener,

following

instructions, getting

along with others,

and having ability

to organize/present

data. Students

also have excellent

communication

skill, and are able

to read and write in

English.

Biology,

Neuroscienc

e

320

hours

3/6/2015 31


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Fabio A.

Recchia

fabio.recc

hia@tem

ple.edu

TUSM Physiology New

pharmacological

and biological

therapies for heart

failure and atrial

fibrillation

TU Health

Science

Campus

The general aim of this project is to identify

new pharmacological and biological agents

for the therapy of heart failure and atrial

fibrillation in experimental dog models.

These are two major pathological conditions

that affect millions of Americans and there is

a pressing need for new therapies.

Research in large animal models is called

"pre-clinical" in that the related discoveries

can be rapidly translated into clinical

practice.

Interest in the

biomedical field

and potential

interest in future

medical studies.

At least the basic

courses of biology

biology,

bioengineeri

ng,

biochemistry

, kinesiology

25

hours/

week

LIQING

JIN

jinliqin@t

emple.ed

u

TUSM Shriners

Hospitals

Pediatric

Research

Center

molecular

mechanisms of axon

regeneration in the

lamprey spinal cord

TU Health

Science

Campus

With molecular biological techniques, we

study the role of local protein synthesis in

axonal tips in axonal regeneration in

lamprey spinal cord.

Diligent - biology,

biochemistry,

molecular biology,

neuroscience, etc. -

-Students are

welcome in our

center.

Medicine or

biology

24-40

hours/

week

Michael

Shifman

mshifman

@temple.

edu

TUSM Shriners

Hospitals

Pediatric

Research

Center

Epigenetics

regulation of axonal

regeneration

TU Health

Science

Campus

The goal of this research is to use the

advantages of the lamprey CNS to test the

hypothesis that “good regenerating” RS

neurons have higher levels of histone

acetylation, favoring activation of a

regeneration program, whereas histone

deacetylation contributes to regeneration

failure after SCI.

self-starter, good

general laboratory

skills

Neuroscienc

e

30

3/6/2015 32


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Shuxin Li

(New as

of 2/19)

shuxin.li

@temple.

edu

TUSM Shriners

Hospitals

Pediatric

Research

Center

Neural repair and

CNS neuronal

regeneration

TU Health

Science

Campus

Our lab is highly interested in neural repair

and CNS axon regeneration research. Our

projects focus on the molecular/cellular

mechanisms for CNS neuronal growth

failure and development of novel and

effective strategies to promote neuronal

regeneration, remyelination and functional

recovery after injury and/or in

neurodegenerative disorders. We employ

various in vitro and in vivo research

approaches, including molecular/cellular

neurobiology, biochemistry, genetic and

pharmacological methods, transgenic over-

expression and knockout mice and multiple

neuronal/axonal lesion models (such as

spinal cord injury, optic nerve crush and

EAE) in mice and rats. We have produced a

number of high impact papers related to

CNS axon regeneration and treatments for

CNS injury. Our lab is nationally and

internationally recognized for discovering

that the leukocyte common antigen related

phosphatase (LAR) is a receptor for CSPGs

and for promoting CNS axon regeneration

with available clinical drugs that suppress

Rho and GSK-3 signaling pathways.

Motivated person

and basic

background on

research.

3/6/2015 33


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

George

Smith

george.s

mith@te

mple.edu

TUSM Shriners

Hospitals

Pediatric

Research

Center

Neuroscience

“Enhancing

Propriospinal

Relays to Improve

Functional Recovery

after SCI”

TU Health

Science

Campus

The prospects of inducing long-distance

functional regeneration of supraspinal tracts

leading to connectivity and restoration of

function remain a challenge. However,

selective treatments induce sprouting,

prevent dieback, or induce short distance

regeneration. These processes, particularly

sprouting, contribute to spontaneous

recovery after injury by forming relays onto

propriospinal interneurons that bypass the

lesion and connect to caudal locomotor

centers. Similarly, transplantation of neural

stem cells or fetal spinal cord tissue into the

lesion site is thought to increase functional

recovery by recruiting supraspinal and

propriospinal inputs to reinforce relays to

downstream motor targets. To date, some of

the best functional recovery has been

observed in fetal transplants into neonatal

animals most likely through formation of

such relays. In adults, the addition of

neurotrophins to the transplant site

enhanced the number of ingrowing

supraspinal and propriospinal axons and

enhanced functional recovery, possibly by

forming relays to bypass the lesion.

However, it has never been directly shown

that transplants induce recovery by relay

formation. In this study, we will investigate

Motivation,

enthusiasm, and

ability to work with

animals.

Bioengineeri

ng

betwee

n 30 -

40

hrs/we

ek

3/6/2015 34


Faculty

Name

Email

Address

Faculty

School or

College

Faculty

Department


Location



Important

selection criteria

Student

Majors

Hours

Per

Week

Young-

Jin Son

(New as

of 2/19)

yson@te

mple.edu

TUSM Shriners

Hospitals

Pediatric

Research

Center/Cell

Biology and

Anatomy

nerve injury and

repair

TU Health

Science

Campus

will carryout a small project with a postdoc

or a graduate student, related with motor or

sensory nerve regeneration using mouse.

We use variety of molecular, cellular and

microscopic techniques. see website for

additional information

http://www.temple.edu/medicine/department

s_centers/research/shriners_hospitals_pedi

atric_research_center_faculty.htm

self-motivated,

good work ethics,

inquisitive -

physiology,

anatomy,

neurobiology,

genetics

biology,

bioengineeri

ng, pre-med,

neuroscienc

e

30-40

hrs/we

ek

3/6/2015 35


Faculty

Name

Allen

Nicholso

n (New

as of

2/19)

Brent

Sewall

Darius

Balciuna

s

Erik

Cordes

(New as

of 2/19)

3/6/2015 36


Faculty

Name

Jacquelin

e Tanaka

Jody Hey

3/6/2015 37


Faculty

Name

Karen

Palter

3/6/2015 38


Faculty

Name

Rachel

Spigler

Rob

Kulathina

l

Robert

Sanders

3/6/2015 39


Faculty

Name

Daniel

Strongin

Eric

Borguet

Graham

Doberein

er

3/6/2015 40


Faculty

Name

Katherine

Willets

3/6/2015 41


Faculty

Name

Scott

Sieburth

William

Wuest

3/6/2015 42


Faculty

Name

Bo Ji

Justin Y.

Shi

3/6/2015 43


Faculty

Name

Krishna

Kant

(New as

of 3/6)

Krishna

Kant

(New as

of 3/6)

3/6/2015 44


Faculty

Name

Slobodan

Vucetic

3/6/2015 45


Faculty

Name

Xiaojiang

Du (New

as of

2/19)

Zoran

Obradovi

c (New

as of

2/19)

3/6/2015 46


Faculty

Name

Sujith

Ravi

(New as

of 2/27)

3/6/2015 47


Faculty

Name

Sujith

Ravi

(New as

of 2/27)

3/6/2015 48


Faculty

Name

Laura

Toran

3/6/2015 49


Faculty

Name

Ilya

Buynevic

h (New

as of

2/19)

Sudhir

Kumar

Opportunit

y for

presentati

on of

results at

a national

Geologica

l Society

of

America

Conferenc

e

(Baltimore

-

November

2015)

3/6/2015 50


Faculty

Name

Sudhir

Kumar

3/6/2015 51


Faculty

Name

Matthew

Stover

(New as

of 2/19)

3/6/2015 52


Faculty

Name

Yury

Grabovsk

y

Adrienn

Ruzsinsz

ky

3/6/2015 53


Faculty

Name

Ke Chen

(New as

of 2/19)

Xiaoxing

Xi

3/6/2015 54


Faculty

Name

Marc A.

Ilies PhD

(New as

of 2/19)

Ana

Gamero

contact

me for

further

details at

mailies@t

emple.edu

3/6/2015 55


Faculty

Name

Hong

Wang

3/6/2015 56


Faculty

Name

John

Elrod

Madesh

Muniswa

my

3/6/2015 57


Faculty

Name

Sara

Jane

Ward

Mahmut

Safak

3/6/2015 58


Faculty

Name

Richard

T.

Pomeran

tz

3/6/2015 59


Faculty

Name

Nora

Engel

(New as

of 2/19)

Brad

Rothberg

3/6/2015 60


Faculty

Name

Glenn S.

Gerhard

3/6/2015 61


Faculty

Name

Parkson

Chong

3/6/2015 62


Faculty

Name

Bettina

Buttaro

Stefania

Gallucci

Bassel E

Sawaya

3/6/2015 63


Faculty

Name

Prasun

K. Datta

(New as

of 2/19)

Xuebin

Qin

3/6/2015 64


Faculty

Name

Adil I.

Khan

PhD

3/6/2015 65


Faculty

Name

Wenzhe

Ho

3/6/2015 66


Faculty

Name

Fabio A.

Recchia

LIQING

JIN

Michael

Shifman

3/6/2015 67


Faculty

Name

Shuxin Li

(New as

of 2/19)

3/6/2015 68


Faculty

Name

George

Smith

3/6/2015 69


Faculty

Name

Young-

Jin Son

(New as

of 2/19)

3/6/2015 70

summer 2015 cst merit research projects · summer 2015 cst merit research projects faculty name ......

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