suppl fig. 1a the clinical protocol is shown schematically

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Page 1: Suppl Fig. 1a The clinical protocol is shown schematically
Page 2: Suppl Fig. 1a The clinical protocol is shown schematically

Suppl Fig. 1a The clinical protocol is shown schematically.

Page 3: Suppl Fig. 1a The clinical protocol is shown schematically

Suppl Fig. 1b The CONSORT diagram of the study enrollment.

Screened for eligibility (n=19)

Excluded (n=5)  Not meeting inclusion criteria (n=5) Declined to participate (n=0)  Died prior to enrolment (n=0)

Enrolled (n=14)

Randomized to Arm 2 (n=7)

 Removed from study prior to vaccination (n=1) - Developed active lung infection (n=1)

Received any vaccines (n=6) Recurred after 1 vaccination (n=1)

Included in analysis (n=5)

Received any vaccines (n=5) Recurred after 2 vaccinations (n=1)

Randomized to Arm 1 (n=7)

 Removed from study prior to vaccination (n=2) - Disease progression during vaccine production (n=1) - Developed dermatomyositis (n=1)

Included in analysis (n=5)