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Supplements and Youth Athletes Cody Blackford, MA, ATC, CSCS

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Page 1: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Supplements and Youth

Athletes

Cody Blackford, MA, ATC, CSCS

Page 2: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Nutrition and Energy Basics

• Basal Metabolic Rate (BMR)

– the rate at which the body uses energy

[burns calories] while at rest to keep vital

functions [breathing, keeping warm] going.

• Total Daily Energy Expenditure (TDEE)

– Also called recommended daily intake (RDI)

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Nutrition and Energy Basics

• Calculate Energy Expenditure – Females: BMR = 655 + ( 4.35 x weight in pounds ) + ( 4.7 x

height in inches ) - ( 4.7 x age in years )

– Males: BMR = 66 + ( 6.23 x weight in pounds ) + ( 12.7 x

height in inches ) - ( 6.8 x age in years )

Activity Level Factor

Little-to-None 1.2

Light (light exercise/sports 1-3 days per week) 1.375

Moderate (moderate exercise/sports 3-5 days per week) 1.55

Very (hard exercise/sports 6-7 days per week) 1.725

Extra Active (very hard exercise/sports & physical job or 2x training) 1.9

Page 4: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Calculating Energy Needs

Example

17 y/o male football player; 67” tall, 185 lbs

(82.7kg), linebacker; in-season (very active).

BMR = 66 + ( 6.23 x 185 ) + ( 12.7 x 67 ) - ( 6.8 x 17 )

= 66 + (1152.55) + (850.9) - (115.6)

= 1954 kcal/day

RDI = 1954 x 1.725

= 3,370 kcal/day

Page 5: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Nutrition Basics

• Macronutrients

– Carbohydrates: 9 kcal/g

– Proteins: 4 kcal/g

– Fats: 4 kcal/g

• How Much

– Carbohydrates: 3.9-10g/day*

– Proteins: 1.2-1.7g/day*

– Fats: 20-30% Total kcal/day

• % Based

– Carbohydrates: 45-65% RDI

– Proteins: 10-35% RDI

– Fats: 20-35% RDI

Page 6: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

*Macronutrient Requirements

● Bagchi, D., Nair, S., & Sen, C. K. (Eds.).

(2013). Nutrition and enhanced sports

performance: muscle building, endurance, and

strength. Academic Press.

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Calculating Macro Needs

• Using same player from previous example;

calculating how many daily kcals each from

carbohydrates, proteins, and fats.

• g/kg calculation:

– Carbs: 83kg x 3.9(8.0)g/kg/day =

324 - 664g/day (1296-2656kcal)

– Proteins: 83kg x 1.2(1.7)g/kg/day =

99.6 - 141g/day (398 - 564kcal)

– Fats: 3370kcal x .20(.30) =

674 - 1,011kcal/day = 75 - 112g

TOTAL KCALS

2368 - 4231kcals

Page 8: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

There’s an app for that!

• MyFitnessPal

• Tap and Track

–Tracks kcals

–Breakdown of macros

–Breakdown in %

–Customizable

Page 9: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Dietary Supplements

2011 Sports Nutrition and Weight Loss

Report:

• “9% annual sales growth and $22.7 billion in

total sales were noted for sports nutrition and

weight-loss products in 2010.”

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Dietary Supplements

“The term dietary supplement represents a wide

spectrum of products, including some fortified

whole foods, herbal products, and ergogenic aids

and products designed to improve work or

performance.”

Term “ergogenic” derived from Greek words ergon (work) and

gennan (to produce)

Dietary Supplement Health and Education Act (DHSEA) 1994:

• DHSEA requires manufacturers and distributors of supplements

to ensure safety of products before marketing;

– “No third-party screening ensures this has happened.”

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Regulation

• Coaches, ATs, team physicians, and

administrators are responsible for knowing,

educating, and encouraging athletes to follow

the code of ethics dictated by their governing

body.

• Know TSSAA’s position or policy on doping

• NFHS website posts position statements on

sports medicine, supplements, ergogenic aids,

anabolic steroids, use of energy drinks, and

hydration.

Page 12: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Resources for Safety • MedWatch: http://www.fda.gov/Safety/MedWatch/default. htm

• Quackwatch: http://quackwatch.org

• Dietary warnings and safety information from the US Food and

Drug Administration: http://www.fda.gov/Food/

DietarySupplements/Alerts/default.htm

• Recall of products: http://www.fda.gov/Safety/Recalls/

default.htm

• Center for Drug Evaluation and Research: http://www.fda.

gov/Drugs/default.htm

• United States Anti-Doping Agency: http://www.

supplementsafetynow.com

• Reporting of dietary supplements: http://www.oig.hhs.gov/

oei/reports/oei-01-00-00180.pdf

• US Department of Agriculture Food and Nutrition Information

Center, dietary supplements (regulations, reports, and

warnings): http://fnic.nal.usda.gov/nal_display/index.

php?info_center¼4&tax_level¼2&tax_subject¼274&topic_

id¼1328

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Evidence of Safety or Harm

• Manufacturer or distributor of product decides

whether to invest in third-party evaluation and

assurance regarding purity and truth in labeling

• Governmental regulation usually based on

postmarket safety of the product, with no truth

in labeling oversight.

• Purity of the product and truth in labeling are

not assured in many products.

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!!! WARNING !!!

• Cases of dangerous contamination and adulteration are

well documented; these may be intentional or

unintentional – Cole MR, Fetrow CW. Adulteration of dietary supplements.

Am J Health Syst Pharm. 2003;60(15):1576–1580.

• US Government Accountability Office (2010)

– Report identified herbal products contaminated with

arsenic, lead, mercury, and pesiticide residues.

• International Olympic Committee Study (2004)

– supposedly non-hormonal muscle building

supplements purchased from U.S. companies

18.8% were adulterated with banned substances

Page 15: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Truth in Labeling

• Sometimes there will be more or less active

ingredient in a product than declared on the

label.

– 2001, study reports that 1 in 12 hormonal

supplements contained 90% to 110% of

labeled active ingredient

– 2000, analysis of 9 brands of

androstenedione (“andro”):

• 6 contained less than 90%

• 1 contained no androstenedione at all

• 1 contained 10mg of testosterone

Page 16: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

What does this mean for athletes?

• Strict Liability means that the athlete is

responsible for the presence of the banned

supplement in his or her system, regardless of

how it got there.

• Athletes risk eligibility if they test positive for a

banned substance, even if it was unknowingly

consumed in adulterated supplements.

Page 17: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Third-Party Verification

• Typically tests for product dissolution, accuracy

of active ingredients as described on the label,

and detectable (tested) impurities or

contaminants.

• Third-party testing does not assure safety or

efficacy but assures truth in labeling and good

manufacturing practices for the batch of

product tested.

Page 18: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Third Party Verification: Truth in Labeling

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Third Party Verification: Purity and

Banned Substances

Page 20: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Third Party Verification: Purity and

Banned Substances

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Third Party Verification: Purity and

Banned Substances

Page 22: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Efficacy of Products

• Manufacturers and distributors of product do

not have to prove the product is effective

• Many ergogenic supplements only have

anecdotal or manufacturers’ claims of efficacy.

• Critical evaluation of scientific evidence -

“scientific evidence” - is a must.

Page 23: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Best Resource

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Efficacy Resources and Fact

Sheets

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Protein Supplementation

• Shown effective in muscle protein synthesis

(increasing muscle mass) when used in

conjunction with resistance exercise.

• Multiple types and digestion speeds

– Slow digesting

– Fast digesting

• Whey Protein

– Fast digesting

– Best when used following intense resistance

training to promote recovery

• Casein Protein

– Slow digesting

– Best used to prevent muscle protein

breakdown during fasting periods (over

night, mid-morning or afternoon snack)

Page 26: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Protein Supplementation

• Amount of protein dosage per ingestion

unclear.

– Most common recommendation is 20g

– Newer studies have shown up to 70g

• Depends on individual response

• Research individually to determine best whey

protein supplement for post-workout recovery -

based on flavor preference, price, ratings, etc.

Page 27: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Creatine (Cr)

• Most research proven performance enhancing

supplement

– 96 published investigations 1994-2003

– 2012 most recent update

• What it does: Regularly has shown increases

in strength, fat free mass, muscle morphology

with concurrent heavy resistance training.

• How it works: increases creatine storage and

promotes faster regeneration of ATP between

high intensity exercise bouts.

– More effective in high intensity, short

duration activities.

Page 28: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Creatine

• Cr Supplementation in Adolescents

– Concerns:

• safety of supplementation in this age

group not established and not

recommended by some authors.

• taking creatine could lead to more

dangerous performance enhancing

supplements.

Page 29: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Creatine in Adolescents

• International Society of Sports Nutrition:

– “younger athletes should consider a

creatine supplement under certain

conditions:

• puberty is past and he/she is involved in

serious competitive training;

• eating a well-balanced caloric adequate

diet;

• understand the truth concerning the

effects of creatine supplementation;

• supplement protocols are supervised by

qualified professionals;

• recommended doses must not be

exceeded...”

Page 30: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Creatine Dosage

• Mixed opinion

– Loading A: 20g/day (4 x 5g throughout

day) for first 5 days.

– Loading B: 20g/day (1g doses every 30-

minutes) for first 5 days.

• Better retention of Cr

– Maintenance: 3-5g/day for duration

following loading

– Daily single dose of 3-6g

– 3-5g before, 3-5g after workout

Page 31: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Creatine and Cramping

• Journal of Athletic Training (2009)

– No substantial evidence currently exists

showing that creatine supplementation

hinders the body’s ability to dissipate heat

or body fluid balance when appropriate

doses are consumed.

– Controlled experimental trials of athletes

exercising in the heat over a short period of

time resulted in no adverse effects from

creatine supplementation.

• Studies do not specify subject ages.

Page 32: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

HMB

• Has been shown effective in decreasing the

amount muscle damage indicators associated

with resistance training.

– Recovery

• Effects on strength and muscle mass:

– Significant increase in fat-free mass and

strength reported when 3.0g/day of HMB

was supplemented in association with

resistance training for 7 weeks.

– 3.0g/day of HMB promotes gains in fat-free

mass and peak isometric torque during a

resistance-training program.

Page 33: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

HMB

• Effects of decreased muscle breakdown

greater in untrained individuals, or those in the

initial phase of training.

– resistance-trained athletes may not respond

to HMB supplementation in the same

manner.

• Greater amounts per day (6g in one study) did

not elicit greater effects than the previously

studied 3g/day.

• Up to 8 weeks of supplementation appears to

be safe and does not adversely affect liver and

kidney function in young male adults.

Page 34: Supplements and Youth Athletes - KOCkocortho.com/files/9214/6169/8285/Supplements_Presentation.pdfEvidence of Safety or Harm • Manufacturer or distributor of product decides whether

Caffeine

• One of the most widely used ergogenic aids in

the world.

• Considerable amount of evidence for enhanced

aerobic endurance following caffeine ingestion:

– Reduced rating of perceived exertion (RPE)

– Breakdown of fats

– Sparing of muscle glycogen (uses up

energy stores slower)

• Research base regarding ergogenic effects for

high-intensity anaerobic and strength-based

performance not as well developed.

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Caffeine

• Research studies documenting acute caffeine

ingestion for enhancing strength and power

performance are ambiguous; proven effects include

– 11-12% of total mass lifted at 60% 1RM bench

press

– Increases in repetition to failure during bench

press

– Increased number of repetitions and higher

peak heart rate during leg press to failure at

10RM

– Increased repetitions to failure during the first

set of a multi-set leg extension protocol

– Increases in peak torque during 3-5 repetitions

of leg extension and flexion

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Caffeine

Majority of studies suggest that ingesting

caffeine in 5-7mg/kg doses will have positive

effects on resistance training exercise

performance.

HOWEVER….

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Caffeine Warning

• Caffeine toxicity; symptoms include:

– Nervousness

– Anxiety

– Restlessness

– Insomnia

– GI upset

– Tremors

– Tachycardia

– Psychomotor agitation

– Death (rare cases)

• Mayo Clinic says 400mg a day appears safe for

adults; 100mg a day for adolescents.

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Energy Drinks

• Caffeine is not the sole stimulant in most

energy drinks

– Guarana

– Bitter orange

– Ginseng

– Taurine

• Adverse effects usually due to caffeine

and additive effects with guarana

• Read labels!!

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Energy Drinks

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Other Common Supplements

• β-Alanine

– Carnosine substrate

– Carnosine acts as a buffer to H+ ions

• Slows acid buildup in muscles/delays

fatigue

• Branched Chain Amino Acids (BCAAs)

– Benefits of supplementation include muscle

recovery and increased immune system

function

• Nitric Oxide Stimulators

– Aim is to increase blood flow to working

muscles

– No conclusive evidence for this supplement

when used alone (usually in pre-workout

supplement form with other ingredients).

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Evaluating Supplements

• Read the label

• Look for specific ingredients and their amounts

• Keep in mind that non-verified products may

not contain amount of ingredient listed

• Beware of “Proprietary Blend” or similar

wording

• Longer list of ingredients = more research

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Evaluating Supplements

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Evaluating Supplements

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Easy Way to Recover

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Sources American College of Sports Medicine, & American Dietetic Association. (2000). Joint Position

Statement: nutrition and athletic performance. American College of Sports Medicine, American Dietetic

Association, and Dietitians of Canada. Medicine and Science in Sports and Exercise, 32(12), 2130.

Bagchi, D., Nair, S., & Sen, C. K. (Eds.). (2013). Nutrition and enhanced sports performance: muscle

building, endurance, and strength. Academic Press.

Besco, R., Sureda, A., Tur, J. A., & Pons, A. (2012). The effect of nitric-oxide-related supplements on

human performance. Sports medicine, 42(2), 99-117.

Branch, J. D. (2003). Effect of creatine supplementation on body composition and performance: a

meta-analysis. International journal of sport nutrition and exercise metabolism, 13, 198-226.

Buell, J. L., Franks, R., Powers, M. E., Laquale, K. M., & Carlson-Phillips, A. (2013). National Athletic

Trainers’ Association Position Statement: Evaluation of Dietary Supplements for Performance

Nutrition. Journal of Athletic Training, 48(1), 1-13.

Clauson, K. A., Shields, K. M., McQueen, C. E., & Persad, N. (2008). Safety issues associated with

commercially available energy drinks.Pharmacy Today, 14(5), 52-64.

Cooper, R., Naclerio, F., Allgrove, J., & Jimenez, A. (2012). Creatine supplementation with specific

view to exercise/sports performance: an update. J Int Soc Sports Nutr, 9(1), 33.

Gallagher PM, Carrithers JA, Godard MP, Schulze KE, Trappe SW. Beta-hydroxybeta- methylbutyrate

ingestion, part II: effects on hematology, hepatic and renal function. Medicine and Science in Sports

and Exercise. 2000;32:2116-9.

Hobson, R. M., Saunders, B., Ball, G., Harris, R. C., & Sale, C. (2012). Effects of β-alanine

supplementation on exercise performance: a meta-analysis. Amino acids, 43(1), 25-37.

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Sources

Orlov, A. (2015, January 31). How to Calculate Your BMR (And Why It Matters). Retrieved April 7,

2016, from http://dailyburn.com/life/health/how-to-calculate-bmr/

Reissig, C. J., Strain, E. C., & Griffiths, R. R. (2009). Caffeinated energy drinks—a growing problem.

Drug and alcohol dependence, 99(1), 1-10.

Sale C, Harris RC, Florance J, Kumps A, Sanvura R, Poortmans JR: Urinary creatine and

methylamine excretion following 4 x 5 g x day(-1) or 20 x 1 g x day(-1) of creatine monohydrate for 5

days. J Sports Sci 2009, 27:759– 766.

Sports, Cardiovascular, and Wellness Nutrition practice group of the American Dietetic Association:

http://www.scandpg.org and http://www.scandpg.org/sports-nutrition/sports-nutrition-fact-sheets

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Cellucor C4

• Beta Alanine - building block of carnosine, a molecule

that buffers acid in muscles; can aid lean-mass gain

• Creatine Nitrate - more water soluble form of creatine;

no support for superiority to other forms of creatine

• Arginine AKG - alleged to increase nitric oxide

production, thereby resulting in vasodilation.

• L-Tyrosine - used to produce noradrenaline and

dopamine; supplemental appears to be anti-stress for

acute stressors; stimulant

• Tetramethyluric Acid - structurally similar to Caffeine,

and preliminary evidence suggests that it activates

similar signalling pathways.

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The Curse

• L-Citrulene - a more effective method of increasing L-

arginine levels in the body than L-arginine

supplementation; results in reduced fatigue and

improved endurance for both aerobic and anaerobic

prolonged exercise.

– There is not enough evidence to support the claim

that L-citrulline supplementation improves power

output during exercise.

• Olive Leaf Extract - appears to have highly protective

effects against LDL oxidation and may also benefit

glucose metabolism and skin health.

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ON Amino Energy

• Free Form Amino Acids for Rapid Uptake

• Essential Amino Acids including BCAAs

• Supports Recovery Before, During & After

Exercise

• Train Longer & Harder with beta-Alanine

• Natural Energizers & Antioxidant Support

• Supports Nitric Oxide Synthesis

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MusclePharm Assault

• Red Beet Extract: high Nitrate content, said to

improve physical performance secondary to Nitric

Oxide. It appears to have some evidence for this

claim in healthy athletes

• Cinnamomom Burmannii: cinnamon; anti-

inflammatory; anti-oxidant; cardiovascular support;

blood-sugar lowering properties in animals

• Choline Bitartrate: mostly used for its cognitive

boosting properties (turning into acetylcholine, the

learning neurotransmitter).

• Glucuronolactone: improved metabolism, blood

flow, aerobic performance*

• Huperzine A: cognitive enhancer that inhibits an

enzyme that degrades the learning

neurotransmitter, acetylcholine