surveillance of invasive and native mosquito vectors and ... project/21 lovcen... · and pathogens...
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University of Montenegro
Biotechnical faculty
SurveilLance of invasive and native mOsquito VeCtorsand pathogENs they transmit in Montenegro – acronym
LOVCEN
Estimated overall duration of the proposed project [months] 36
Proposed start [month, year] 05/2014
Proposed completion [month, year] 03/2017
Requested grant amount [€] 397998,46
Project leader: Pajovi ć Igor
1/21 Presentation LOVCEN, March 2014 08:56
List of participants - institutions
Proposed partner institutions on the project are:
- Applicant institution - Biotechnical faculty+
- 3 RSRI (national registered scientific research institutions) –Institute for Hydro Meteorology and Seismology,Institute for Public Health andNatural History Museum.++
- 6 ISRI (international scientific research institutions) –3 from EU (2 from Italy, 1 from Romania) and3 from region (Serbia)
and
- 1 NS (national small company)
In total 11 institutions and 30 researchers without technical staff.
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Chikungunya fever:Italy in 2007,France in 2010.
Dengue fever:France and Croatia in 2010,Portugal in 2012-2013.
Europe is vulnerable to
Mosquito vectors (MV) and mosquito-borne diseases ( MBD) are rising threat to Europe
Europe is vulnerable to “tropical” MBD outbreaks.
Montenegro is not an exception:
West Nile virus fever in 2013
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Human and
Animal
Health
High Education
and inovative
“know how”
High education – capacity building for excellence in the research and innovation in surveillance of mosquito vectors (MV) and mosquito-borne diseases (MBD)
Increasing the quality of human life
by decreasing the medical, social and
financial impact of MV and MBD’s
Health
Environment
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1. Capacity building
44 trainings, 27 equipment acquisitions
2. Innovative research
- SIT,
- implementation of Guidelines of ECDC,
- mobile phone application for surveillance of invasive and
indigenous mosquito species,
- evaluation of novel non-chemical, biodegradable materials for
control of mosquito larvae
Activities designed to achieve high Impact
control of mosquito larvae
3. Dissemination
- developing Web Site,
- socio economic impact check,
- public (radio, TV, newspapers) appearances
4. Sustainability
- support of the idea by two Ministries – MH and MSDT
- recruitment of YR, EU competitive research, knowledge transfer
- SMEs involvement
- community participation/ KOMARAC /
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(a) Distribution of mosquitoes in Montenegro;
(b) Identification of mosquito vector species in Montenegro;
(c) Low-cost and sustainable monitoring system - KOMARAC
(d) Detection of pathogens carried by mosquito vector species;
Outcomes - novelties for Montenegro, highly valuable and
competitive at EU level
(e) Capacity for modelling of climate changes influence on MV and MBD;
(f) Survey and feedback on stakeholder’s opinions about direction of the
research in vector borne disease prevention/control and
(g) Link through applicable research with business.
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(WP1) Collaborative interdisciplinary research on native/invasive mosquitoes and pathogens
they transmit in Montenegro and development of non-chemical control measures
(WP2) Twinning through exchange of know-how and experience and dissemination activities
LOVCEN WPs - combining capacity building and research in different
scientific disciplines
(WP3) Acquisition of research equipment and innovation capacity building
(WP4) Management
7/21 Presentation LOVCEN, March 2014 08:56
Aim Measurable targets
Collaborative Research
• reports of invasive and native mosquito fauna and their
distribution
• mobile phone and server software for mosquito surveillance
• reports of pathogen identification in vector mosquitoes
• social impact check
• best practices and policy recommendation
• reports on efficiency of SIT
• reports on other non-chemical methods for mosquito control
• reports on scientific visits of researchers from MCM to partner
international research institutions
• reports on training visits of researchers from partner
Clearly measurable targets
Exchange of Know-How and Experience
and Dissemination activities
• reports on training visits of researchers from partner
international institutions to MCM
• reports on participation of the MCM research staff at
international conferences
• report about web page development and maintenance
• reports on organized promotional and dissemination activities
Acquisition of Equipment and
Capacity Building
• reports about purchasing activities and installation of
equipment
• reports on training in research skills and innovation capacity
building
Management
• scientific and financial plans for project realization
• progress reports/annual progress reports of project realization
(scientific and financial).
• report about LMT, PMT and APM meetings
• final report of project realization
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“wider impact beyond the scientific community”LO
VC
EN
Research ResultsImpact on surveillance policies
Future research strategies
Personell with interdisciplinary
background
Capacity building
Policy makers
&
Dissemination and capacity building
LOV
CE
N &
Grant Agencies
National surveillance
system
Business Partners,
NGO’s
Health system, Hospitals,
Laboratories
Laboratory personnel
Researchers
Meteorologists
Community
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LOV
CE
NMapping of MV
distribution
ECDC/EFSA
MBD in MontenegroNational Reference Center
Dissemination and sustainability
European Health Policy Makers
European Research Policy
Makers
European Reference Centers
LOV
CE
N
Control strategies
National Public Health Service
Environmental Agency
National Policy Makers
We have clear vision about sustainability of activities started by MCM beyond the 36 months of the
LOVCEN project.
Ministry of Health and Ministry of Sustainable Development and Tourism of Montenegro already
expressed their interest in the thematic area proposed by LOVCEN project.
ERA
networking towards
Horizon 2020
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Project Leader
10 out of 13 researchers gathered to form MCM.
They will all be actively engaged in
collaborative research and development of non-chemical control measures
(WP1),
twinning through exchange of know-how and experience and dissemination
Early stage, young researchers (YR) and students
twinning through exchange of know-how and experience and dissemination
activities (WP2),
acquisition of research equipment and innovation capacity building (WP3)
and management (WP4).
Introduction of teaching on MV and MBD (WP 2) will recruit new students to
take their master and PhD thesis in this subjects.
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We did our best to have a clearly-defined starting
Imp
act
We tried to avoid our project looks like this:
To start from somewhere here:
To finish (“successfully”) after a few years somewhere here:
Several years later to be back somewhere here:
We did our best to have a clearly-defined starting point (SWOT):
Imp
act
start finish long-term
start finish long-term
Clearly-defined activities and evidence of progress to define the Impact at the end (WPs):
Ensured long-term Impact after the end(sustainibility plan):
And we hope we did it well.
12/21 Presentation LOVCEN, March 2014 08:56
West Nile virus fever in 2012 one unconfirmed casehttp://ecdc.europa.eu/en/publications/Publications/EU-summary-report-zoonoses-food-borne-outbreaks-2012.pdf#page=241
2013 four unconfirmed caseshttp://www.ecdc.europa.eu/en/healthtopics/west_nile_fever/west-nile-fever-maps/pages/index.aspx
QUESTION a) Based on statistics, what is prevalence of MBD in Montenegro over last decades – are there serious cases of outbreak of MBD? How
situation is expected to change in the future?
Dengue ?
Chicungunya ?
2012-2014 Malaria imported cases1- 3 cases/year
2010-2014 11 Leishmania cases
Phleboviruses ?
JEV ?
Remi Charrel, Marseille University
Establishment of vectors and MBD surveillance syste m is crucial need for Montenegro (EU).
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QUESTION b) Can the same approach be expedited to other decease transmitting species – statistically which are the most relevant ones/ are the mosquitoes at the top and how easy is to include 2 or more species in the
surveillance protocol?
Statistically which are the most relevant decease transmit ting species, are themosquitoes at the top?
Mosquitoes – most dangerous animals in the worldhttp://list25.com/the-25-most-dangerous-animals-in-the-world/2/
mosquitos transmit diseases to almost 700 million people annually resulting in 1 to 3million deaths every year
How easy is to include 2 or more species in the surveillance pr otocol?
KOMARAC – will allow many more mosquito species to be included(e.g., malaria vector, WNV vector, ...)
Can the same approach be expedited to other disease transmit ting species?
Yes, it’s easy to include all invasive mosquito species that are threatening Europe at themoment (all are container breeders so larvae inhabit same/similar breading places).Aedes japonicus, Ae. aegypti, Ae. koreicus, Ae. atropalpus, Ae. triseriatus.
million deaths every year
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QUESTION c) How large BRIC countries or USA are solving the issue?
Brasil, Rusia, India, China and South Africa
1. - Diseases of poverty: TB, Chagas Disease, Malaria, Chikungunya, Dengue, Hepatitis,Diarrheal Diseases, Visceral Leishmaniasis and HIV remain major problems.
2. - The most deadly MBD in BRICS are malaria and dengue hemorrhagic fever .2. - The most deadly MBD in BRICS are malaria and dengue hemorrhagic fever .
BRICS Health Ministers’ meeting Delhi 2012. Declaration:
“We are aware that an effective health and disease surveillance is the key strategy forcontrolling communicable diseases... to detect early warning signals to control outbreaks andto respond quickly on resource allocation for specific areas.
For this purpose, we recognize the need to build capacity for effective health and diseasesurveillance systems , including setting up surveillance units, strengthening of laboratories.”
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QUESTION c) How large BRIC countries or USA are solving the issue?
USA
CDC organizing National based surveillance program (for over 60 years)
e.g. WNV surveillance program since 1999
States: Ae. albopictus since 1986 (Texas).
All major critical needs in vector biology and management of vector-borne diseases definedby Institute of Medicine, National Academy of Sciences USAare prioritized in LOVCENare prioritized in LOVCEN
LOVCEN propose using the Guidelines published 2012 by ECDC,Belgium 2013.,Greece and Italy 2014.Montenegro – forth in Europe.
In a sense, arboviruses and other VBD (MBD) epidemics are like floods, hurricanes, or tornadoes: theyoccur sporadically, but their precise time and location can not be predicted . Beasley et al. 2013.
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Link through applicable research with business.
Development of non-chemical control measures
QUESTION d) Elaborate on commercialization and market potential?
Research ResultsImpact on surveillance policies
Policy makers
LOV
CE
N
Policy makers
&
Grant Agencies
National surveillance
system
Business Partners
Control measures
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QUESTION e) Elaborate on sustainability of the project?
educationno courses
available on the subject
no capacity for
independent modules on medical, veterinary entomology
and parasitology
detection of other pathogens of
Targets Start of project End of project After the end of project
early warning system enhancedpublic awareness on MV and MBD raised
medical entomology included in existing
courses
equipment
human resources
research capacity
no capacity for detection of MB
viruses
moderate level or not trained
national projects
detection of other pathogens of medical and veterinary
importance
training of the others
Horizon 2020
detection of MB viruses enabled
highly trained
COST Action TD1303 VectorNet
Bilateral projects
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We will already during the project initiate discussion and
negotiation with institutions ready to financially support MCM
Recruitment of YR
EU competitive research
Knowledge transfer
SMEs involvement
QUESTION e) Elaborate on sustainability of the project?
Staff form MCM institutions, will be actively involved in writing new proposals, utilizing
Support of the idea by Ministry of Health, Ministry of Sustainable Development and Tourism, as well
as Agency for Environmental Protection
Staff form MCM institutions, will be actively involved in writing new proposals, utilizing
new equipment, training activities and knowledge transfer to SMEs and other businesses
in order to provide sustainability for capacities developed during the LOVCEN project
Mosquito surveillance program will be continued on most sustainable way, with community
participation, utilizing KOMARAC mobile phone application developed within WP1
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