swine flu briefing 30 apr 2009 (2)
TRANSCRIPT
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Dr Armid AzadehPandemic Specialist
International SOS
Swine Flu Briefing
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Agenda for today
Evolution of the ThreatSwine Flu How it all Started
Is this a PANDEMIC?
What can you do now?
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Evolution of the Threat
Thursday,April 23rd
Mexico: 120 / 20
Mexico City 115 / 203 other regions 5
USA: 2
2 California
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Mexico: 850 / 59
Schools Close Airport Screening
USA: 6
4 California, 2 Texas
Evolution of the Threat
Friday,April 24th
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Mexico: 1324 / 59
No public gatherings Closed libraries
USA: 8 - add 2 Kansas
Suspect NYC (8)
Evolution of the Threat
Saturday,April 25th
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Evolution of the Threat
A Fast Moving Target: Where We are Now
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Evolution of the Threat
Country Cases What Else?
Mexico Many Most severely impacted (33 confirmed)
Suspect 1,600+ cases and 150 deaths
US 91 New York, Texas, California, Kansas, Massachusetts,Michigan, Arizona, Indiana, Nevada, Ohio.
Canada 13 Two provinces: Nova Scotia (4), British Columbia (2)
Costa Rica 2 San Jose, Heredia
Austria 1 Vienna
New Zealand 3 Another 11 likely to be confirmed from group of 25 students
Israel 2 Both traveled to Mexico
UK 5 Scottish honeymooners
Spain 10 Travel partners
Germany 3 Bavaria, Hamburg
Peru 1 Lima
As of April 30th
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S-OIV (Swine-Origin Influenza Virus) flu:
Symptoms similar to seasonal human influenza.
o Mild to severe.o 1-4 days after exposure to get sick on AVERAGE
o EARLY: Sore throat, Runny nose (clear) and Itchy eyes
o PROGRESSION: Fever, Muscle Aches, Fatigue, Joint Aches, Cough
S-OIV Outside Mexico Most cases presented as mild.
Few cases required hospitalization
Only one death to date in Texas, so far, low % death
S-OIV in Mexico Mild to severe
Some resulting in death but likely a much highernumber of infections, so % deaths unknown
Evolution of the Threat
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Influenza: How it is spread
Mainly by droplet spread drops to ground
o Droplets containing the virus produced when coughing, sneezing and talking
o Deposited in mouth, nose, eyes, or via common surfaces
Possible by Aerosol spread floats in air (1 meter rule)o Unusual
o Possible in very crowded conditionso Subways, Planes
Why Influenzas can spread quickly:
May be contagious BEFORE developing symptoms (1 to 2 days) Contagious for 7-10 days AFTER symptoms develop; children can be longer
Some cases are mild and undetectable
Virus can survive on hard surfaces for many hours (i.e. door handles, etc.)
According to the CDC and WHO this virus is unlikely to be contained
Evolution of the Threat
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WHO
Low risk of human cases 1
Higher risk of human cases 2
3
4
5
6
Pandemic alertNo or very limited human-to-humantransmission
Evidence of increasedhuman-to-human transmissionNew virus causes
human cases Evidence of significanthuman-to-human transmission
PandemicEfficient and sustained significanthuman-to-human transmission
Inter-pandemic phase
New virus in animals,
no human cases
Evolution of the Threat
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WHO
Low risk of human cases 1
Higher risk of human cases 2
3
4
5
6
Pandemic alertNo or very limited human-to-humantransmission
Evidence of increasedhuman-to-human transmissionNew virus causes
human cases Evidence of significanthuman-to-human transmission
PandemicEfficient and sustained significanthuman-to-human transmission
Inter-pandemic phase
New virus in animals,
no human cases
Evolution of the Threat
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Swine Flu How it all Started
Usually infects pigs
Infections in Humans uncommon2005-2009: 12 cases in the USA
1988 (Sept.): 1 fatal case in Wisconsin
1976: 200 cases (1 fatal) in an outbreak in New Jersey
S-OIV is a new strain
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Swine Flu How it all Started
Pig farm and Mexican child?
Probably started end of March
April 22nd
CDC and WHO find cases in Californiaand Texas to be linked to Mexico, days before furthercases in North America, EU, and Middle East.
Prior to S-OIV: Close pig contact
This virus: Human to Human spread
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Swine Flu How it all Started
Source: http://www.sciencemag.org/cgi/content/full/299/5612/1502
S-OIV (Swine-originInfluenza Virus)
H1N1
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Edgar Marcus
University of Washington School of Medicine
The Pandemic Clock istickingwe just dont know whattime it is.
Is this a PANDEMIC ?
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1957: Asian Flu
1-4 milliondeaths
1968: Hong Kong Flu
1-4 milliondeaths
1918: Spanish Flu
50 million deaths
Credit: US National Museum of Health and Medicine
Is this a PANDEMIC ?
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Pandemic Severity Index (PSI)
The substantial difference inthe severity of the illnessassociated with infections from
the same virus, the relativelylow number of cases detectedin the United States, and
insufficient epidemiologic andclinical data to ascribe a PSI
CDC Apr 09
Is this a PANDEMIC ?
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Is this a PANDEMIC ?
Number 1 threat to Business Continuity Today
The threat is increasing
Possibly 60-100 million dead (HIV has 40 million)
Significant disruption to global economy (ADB
postulates a decrease in global GDP of 800Billion $)
Business is Darwinian Survival of the Fittest
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What can you do NOW?
Protect yourself: Non Pharmaceutical Interventions
Hygiene, Hygiene, Hygiene
Hand washing can decrease respiratory infections by
35%Hand sanitizers can kill 95% of germs on your hands
Stay away from crowded areas
Wh d NOW?
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What can you do NOW?
Protect yourself: Personal Protective Equipment
Surgical masks can prevent droplet spread Ideal for crowded areas
N95 masks, gloves, gowns?
Avoid contact rather
Wh d NOW?
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What can you do NOW?
Protect yourself: Seasonal Vaccination
Does not seem to protect against S-OIV Diagnostic benefits
Continue normal best practice use
6 months before S-OIV specific vaccine
Wh t d NOW?
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What can you do NOW?
Protect yourself: Antiviral medication
Tamiflu (oseltamivir) and Relenza (zanamivir)
Roches priorities
1) WHO
2) Pending Government and other orders
3) New Government orders
Wh t d NOW?
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What can you do NOW?
Protect your business: Pandemic Consulting
Implement existing Pandemic PreparednessPlans (PPP) or
Develop a customized PPP
Provides a Crisis Management Tool
Complements Business Continuity Initiatives
Pre-emptive measure, development is notsuitable for Phases 4-6
Wh t d NOW?
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What can you do NOW?
Stay Informed: Keeping your finger on the pulse
http://urgent.internationalsos.com
Pandemic Information Services (PIS)
Wh t d NOW?
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What can you do NOW?
What can you do NOW?
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What can you do NOW?
What can you do NOW?
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What can you do NOW?
What can you do NOW?
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What can you do NOW?
Take home message
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Take home message
1) Pandemic is a real risk (yesterday birds,today pigs, tomorrow - ?)
2) Hygiene, Hygiene, Hygiene!3) Secure, trusted information source
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PIS screenshots