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Department of Ophthalmology and Visual Sciences Illinois Eye and Ear Infirmary University of Illinois College of Medicine

1855 West Taylor StreetChicago, IL 60612

symposia & events 2016

ONE VIS

ION

2014-15

AND EAR INFIRMARY

February 20-26, 2016 9th Annual Illinois Eye Review

Friday, April 22, 2016 9th Annual Retina Symposium

Wednesday, May 25, 2016 2016 Spring Glaucoma Symposium

Friday, June 17, 2016 40th Annual Alumni / Resident Day

Sunday, October 16, 2016Alumni Reception at the AAO Meeting

Saturday, October 22, 2016 The Chicago Chronic GVHD Meeting

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CLESS FAMILY OPHTHALMIC SURGICAL TRAINING AND SIMULATION CENTERThe Illinois Eye and Ear Infirmary is known as a leader in the field of ophthalmic training in the region and in the nation. One component of this leadership is providing the highest level of surgical training that is available. This year we inaugurated the 9 station state-of-the-art Cless Family Ophthalmic Surgical Training and Simulation Center (Cless Lab), the premier center for ophthalmic surgical training in the Midwest. The Cless Lab will be home to surgical training courses, webcasting and live surgery streaming as well as surgical simulation technol-ogy. A generous investment made by the Cless Family Foundation, along with support from faculty and alumni, made this vision a reality. Establishing the Cless Lab is an enormous advancement in how we train our residents and surgical fellows. It is an active learning environment allowing for a virtual-reality simulation experience within which attention to the finest, most minute details, such as the careful orchestration of hand and foot instrument manipulation, can be perfected without putting patients at risk. It will no doubt significantly increase trainees’ aptitude and confidence when performing in a live operating room.

The virtual connections this equipment makes possible will enable us to examine how fellow surgeons from all corners of the world do work, and repeat it right here. This exposure to new information and practices will fuel the innovation and breakthroughs that will happen here first. And, when they do, we can share them with the rest of the world right from the Cless Lab. We now are able to provide services few places in the world can offer. Our faculty, residents, fellows, alumni and local ophthalmologists can learn more, innovate faster and pioneer surgical curriculum because of these connections.

LEADERSHIP

Left to right: Drs. Sugar, McMahon, Shahidi, Mieler and Rosenblatt—not pictured, Dr. Chan

Mark I. Rosenblatt, MD, PhD, MBA | Professor and Department HeadLions of Illinois/Charles I. Young Chair in Ocular Research

Joel Sugar, MD | Vice Chair for Clinical OperationsJoel Sugar MD Professor in Ophthalmology

William F. Mieler, MD, FARVO | Vice Chair for EducationCless Family Professor in Ophthalmology

Mahnaz Shahidi, PhD | Vice Chair for ResearchMorton F. Goldberg MD FACS Professor in Ophthalmology

Timothy McMahon, OD, FAAO | Vice Chair for OptometryProfessor of Ophthalmology

R. V. Paul Chan, MD, FACS | Vice Chair for Global Ophthalmology Professor of Ophthalmology

1 Leadership2 Shedding Light on the “Bionic Eye”4 Artificial Cornea Program Flourishes6 PROSE Clinic Makes Strides8 Stem Cells and Sight10 Clinical Services/Faculty28 Research Faculty32 Sponsored Research34 Clinical Investigations and Trials36 Giving38 Education40 Publications48 In Memoriam; Investiture49 Cless Lab

IN THIS ISSUE

CREDITSWritersLisa HoltonMargaret Doyle

Editor Laurie Walker

Designer Lisa Birmingham

Contributors Margaret Chervinko, Lauren Hughes, Cristina Lee, Kristen Scheurich, Laurie Walker

Photography Cathy Carroll, Joshua Clark, Roberta Dupuis-Devlin, Mark Janowicz

On the coverVisionary by Gwyn Newcombe

OneVision | 1

A MESSAGE FROM THE DEPARTMENT HEAD

I am deeply honored to serve as the Head of the Department of Ophthalmology and Visual Sciences at the Illinois Eye and Ear Infi rmary/University of Illinois College of Medicine.

The Department has a historic legacy of unparalleled clinical care, outstanding education, and innovative research. This could not have been done without the combined efforts of our faculty, staff and supporters. For over 155 years, the Infi rmary has been leading the way in advanced care for patients who have some of the most serious and complicated eye conditions. The subspecialty services and clinicians in the Department are nationally known for providing this care. We all share in this invaluable commitment to treating and curing eye diseases such as cataracts, glaucoma, and age-related macular degeneration.

Ophthalmologic innovation is happening here.

The modern healthcare landscape and the rapid development of new technologies present us with a unique opportunity to foster innovation and pursue new connections between medicine and engineering to address complex ophthalmic conditions. We are pursuing the development of new fellowship opportunities, including ones in global ophthalmology, which will allow us to inspire innovation here at home and impact patients and clinical care around the globe. Our scientifi c discoveries will infl uence how we treat the most serious and complicated eye conditions, and enhance the quality of life for our patients.

Our Illinois Eye and Ear Infi rmary (IEEI) residents and trainees have shaped our depart-ment, programs and clinics. Their commitment to innovative, inspired and impassioned medicine has helped to establish IEEI as a national center for excellence in resident education. We are proud to train the best and brightest in ophthalmology and we are excited to roll out a brand new surgical curriculum for our trainees in 2016 that corre-sponds with our new state-of-the-art Cless Family Ophthalmic Surgical Training and Simulation Center.

Innovative medicine is happening now.

In the Department of Ophthalmology and Visual Sciences, we are pioneering innovation in three important areas: high-resolution functional imaging, nanoscale device develop-ment and tissue engineering to help us better diagnose and treat eye disease earlier, and preserve the sight of our patients.

In order to continue to lead and stay in sync with advances in medicine, science and technology, we have established an exciting partnership with the University of Illinois College of Engineering at Urbana-Champaign. This partnership will support joint confer-ences, train physicians and scientists, and collaborate between departments to develop solutions for sight-threatening diseases. Our intentional convergence of medicine and engineering will greatly improve ophthalmic conditions around the world.

Our new Ophthalmology Clinical Trials Center underscores our commitment to medical research, which has contributed to advances in Ophthalmology and related areas of medicine. These fundamental discoveries impact our academic medical program and allow us to provide quality eye care to those in need.

We offer our gratitude to our friends and supporters and invite you all to join us on this journey for ongoing innovation, productivity and discovery.

Mark I. Rosenblatt, MD, PhD, MBA

Professor and HeadDepartment of Ophthalmology & Visual SciencesLions of Illinois /Charles I. Young Chair in Ocular ResearchDirector, Corneal Regenerative Medicine Laboratory

Medical SchoolUniversity of Miami (PhD, Biochemistry)

Residency in OphthalmologyMassachusetts Eye and Ear Infi rmary

Clinical FellowshipMassachusetts Eye and Ear Infi rmary (Cornea)

Research FellowshipSchepens Eye Research Institute

Graduate SchoolNew York University (MBA)

2

The Argus II® retinal prosthesis system – also known as the “Bionic Eye” trial – has been making news at the Illinois Eye and Ear Infirmary’s (IEEI) Department of Ophthalmol-ogy since manufacturer Second Sight named the IEEI one of 13 North American clinical testing sites after getting FDA approval in 2013.

“It’s the chance to give some sight back to patients blind from retinitis pigmentosa. Right now, there is no other way you can return vision to completely blind patients,” explains project leader Jennifer I. Lim, MD. The Argus II system is designed to restore limited sight to individuals suffering from retinitis pigmentosa, a genetic disease that causes progressive blindness by destroying the light-sensing cells in the retina. Eventually, this artificial retina system may help tackle other sight-destroying diseases like macu-lar degeneration.

The University of Illinois Hospital & Health Sciences System is the only medical center in Illinois selected to offer the artificial retina. Lim says the success of the device – a sur-gically implanted chip on the retina that wirelessly receives informa-tion from a head-mounted camera to help blind individuals “see” light and shapes in black and white – de-pends on the patient’s motivation and willingness to undergo “visual training after implantation” to learn how to use the device.

The device uses an electrode array that goes directly onto the patient’s retina. The electronic chip is connected to a silicone strip that holds a receiver and is mounted to the outside of the eye. There is no discomfort and the current technology is still in the early phase, Lim adds. “It’s not right for everyone” suffering from RP, Lim explains. “A pa-tient has to be comfortable knowing that they will be im-

SHEDDING LIGHT ON THE “BIONIC EYE”The University of Illinois’ Argus II trial moves ahead, returning sight to the blind.

planted with an electronic device and that the vision will not be ‘normal vision,’” she explained. At this time, the de-vice does not allow for enough resolution to see faces or colors. However, for many patients, the added visual in-formation provided by Argus II can improve the patient’s ability to navigate paths, find doorways and “see people moving about,” returning a significant degree of visual in-dependence to their lives. Additionally, given advances in engineering which allows technology to become smaller and more powerful over time, vision outcomes, comfort and other features of the bionic eye project will improve.

“Today, depending on how severely impaired a patient’s vision is, a patient might be able to see a white line that

can help them walk independently or be able to sort clothing into light and dark colors,” Lim explains. Fu-ture upgrades to the Argus system – named for the all-seeing giant of Greek mythology – might not only eliminate the current required bulky headgear of dark glass-es and head-mounted camera but also provide the possibility of sharper images.

Lim has worked with the inventor of the device, Mark S. Humayun, MD, PhD, the biomedical engineer and retina physician who devel-oped the bionic eye at the Univer-sity of Southern California. She

points out that such collaborative relationships are com-mon at the Department of Ophthalmology.

“The Department has always been a place of innovation,” said Lim. “A lot of the most common procedures you see today were in clinical trials at the IEEI including the first clinical trials for diabetic retinopathy, macular degenera-tion, vein occlusion and sickle cell management. We are just in the early stages with this implant,” she said.

“A lot of the most common procedures you see today

were in clinical trials at the IEEI including the first clinical trials for diabetic retinopathy,

macular degeneration, vein occlusion and sickle cell

management.

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“It’s the chance to give some sight back to patients blind from retinitis pigmentosa. Right now, there is no other way you can return vision to completely blind patients,” explains project leader Jennifer I. Lim, MD.

Argus® II illustration courtesy

of Second Sight Medical

Products, Inc.

4

For over 150 years, the Department of Ophthalmology and Visual Sciences at the Illinois Eye and Ear Infirmary (IEEI) has provided the field of ophthalmology with a long list of firsts in research, surgical technique and groundbreaking patient care.

Henry Winters knows this personally. Winters’ life changed on Jan. 5, 1978 when he suffered chemical burns over 60 percent of his body at the manufacturing plant where he worked as a supervisor. “I got hurt at 27 years of age, and I was in suspended animation from that day,” said Winters, who was com-pletely blind for three years before receiving his first of several trans-planted natural corneas starting in the 1980s.

Unable to work or drive from the day of the accident, Winters got minimal and temporary improve-ment from those transplants and in recent years, he noticed again that the remaining vision in his left eye began to worsen. He and his wife started to look for other options, and in 2012, Winters and his doctor M. Soledad Cortina started discussing the transplantation of the ar-tificial cornea known as the Boston Keratoprostheses, or KPro. KPro is now considered a surgical option for patients with poor prognosis for standard corneal transplants or whose corneal transplants have failed. Later in 2012, Win-ters was implanted with a Boston Type 1 KPro. After more than 30 years, he finally saw clearly from his less-injured left eye.

“It was so exciting – it was the first time out of all those years that I got a chance to see me,” Winters explained. “I could go places, see places and I could read. When you start seeing the words again after you’ve heard them all that time, they don’t feel the same. I was finally able to get familiar again with what I saw.”

Now 65, Winters is retired and has elected not to try to drive. But seeing again reminded him how withdrawn he was for so much of his life.

“The Department of Ophthalmology at the IEEI has a par-ticular and unique approach to the artificial cornea. We un-derstand that these patients suffer from complex eye dis-

ARTIFICIAL CORNEA PROGRAM FLOURISHESIt takes a particular kind of patient to assure success, but the Department of Ophthalmology’s work with the toughest cases has made it the Midwestern leader in artificial cornea transplantation.

ease and we have formed a team of specialists to provide them with the most comprehensive care possible. At the IEEI we have incorporated cornea, glaucoma, vitreoreti-nal, oculoplastics, contact lens and uveitis specialists into the artificial cornea team resulting in an interdisciplinary approach” said Cortina, Director of the Artificial Cornea Program at the University of Illinois College of Medicine.

The Department has one of the largest artificial cornea programs in the country with a strong research team to comple-ment the large clinical program. Our goal is to advance the field of artificial cornea and we have made significant contributions including improvement of surgical outcomes using high resolution imaging to evaluate the formation of damag-ing membranes behind the Kpro device and studying the formation of potentially dangerous microbial biofilms on the device. Additionally, our engineering and basic science

team lead by Drs. Yu and Rosenblatt is investigating new materials and designs for a novel Keratoprosthesis device.

Cortina and fellow faculty member Jose de la Cruz have published a seminal first textbook on KPro technology and transplant. The team gathered the latest and most compre-hensive knowledge and best practices on the device from leading specialists around the world and published “Ker-atoprostheses and Artificial Corneas: Fundamentals and Surgical Applications” late in 2014. Says Cortina: “Much of what you will find in the book goes beyond current litera-ture to experiences that have not been shared anywhere else. All aspects of KPro surgery, from history and preop-erative evaluation to surgical techniques and postopera-tive management of complications, are addressed by more than two dozen leading surgeons as chapter authors in the first edition.

As the work of the Artificial Cornea Program continues, patients like Winters illustrate the Department’s unique approach to the toughest cases in eye medicine. “Our patients come to us with a variety of visual and physical challenges that few treatment centers see,” said Cortina. “We believe that our interdisciplinary approach allows us to transform the lives of some of our sickest patients.”

As the work of the Artificial Cornea Program continues,

patients like Winters illustrate the Department’s unique approach to the toughest cases in eye medicine.

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“It was so exciting – it was the fi rst time out of all those years that I got a chance to see me,” Winters explained. “I could go places, see places and I could read...I was fi nally able to get familiar again with what I saw.”

Front Part

Corneal Graft

Back Plate

Front Part

Corneal Graft

Back Plate

6

PROSE CLINIC MAKES STRIDESNew prosthetic solutions help patients regain sight, mobility and independence

PROSE (short for Prosthetic Replacement of the Ocular Surface Ecosystem) is a device and treatment system that aims to restore vision, promote healing and improve the quality of life for patients with complex corneal disease.

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When Dr. Ellen Shorter, OD, FAAO joined the Department of Ophthalmology and Visual Sciences at the Illinois Eye and Ear Infi rmary (IEEI), one of her fi rst objectives was to complete the intensive BostonSight® PROSE Clinical Fellowship.

Pioneered at the Boston Foundation for Sight, PROSE (short for Prosthetic Replacement of the Ocular Surface Ecosystem) is a device and treatment system that aims to restore vision, promote healing and improve the quality of life for patients with complex corneal disease.

In 2010 the IEEI opened its PROSE Clinic, one of only 12 in the United States, with Shorter as its fi rst director.

“Most of our patients have severe ocular surface disease or advanced corneal ectasia,” Shorter explains. “Many of our patients have been to multiple eye doctors and are frus-trated. PROSE treatment is a fi nal option when other standard thera-pies have failed.”

For many patients, PROSE may be the ideal and sometimes only treatment that can restore vision and dramatically reduce eye pain and light sensi-tivity. PROSE offers hope to patients with conditions such as Stevens-Johnson syndrome (SJS), severe dry eye syn-drome, Sjogren’s syndrome, keratoconus, pellucid margin-al degeneration (PMD), ocular trauma and post-transplant or LASIK complications.

For example, Shorter notes that several of her patients have had cancer and may suffer from chronic graft versus host disease (cGvHD), which can occur six to 12 months after a bone marrow transplant. “Patients with ocular cGvHD have severe dry eye with constant, debilitating eye pain and light sensitivity,” she explains.

PROSE patient Sheri Rapaport had no experience with cancer but had developed keratoconus, a degenerative corneal disease, in her 20s. She learned about PROSE from a friend’s son who had leukemia and developed cGvHD. He was a medical student, and had done some research on the PROSE devices.

Rapaport, 67, had undergone four cornea transplants over the previous four decades with only minimal success. “Every procedure worked for a short time,” she explained, “then the keratoconus took over again.” Eventually, Rapa-port couldn’t drive anymore or perform everyday tasks due to her severely diminished eyesight. “Even going to the grocery store was a challenge,” she recalls.

Rapaport conferred with her doctors at Milwaukee’s Eye Institute and mentioned she had heard about PROSE. They referred her to the Department’s PROSE Clinic and after her fi rst visit to Chicago in January 2014 she planned to began treatment that summer.

PROSE prosthetics are thin transparent devices made of gas-permeable plastic that allow oxygen and a healing sa-line solution to reach the ocular surface. The device fi ts under the eyelid and rests on the sclera (the white tissue of the eye), vaulting the cornea, and creating a reservoir of saline solution that continuously bathes the diseased eye in oxygenated artifi cial tears. The result is a new, smooth

optical surface.

“I could see with the PROSE de-vices immediately,” says Rapaport.

All PROSE devices are custom-ized with computer-aided design (CAD) software to precisely fi t the patient’s unique eye shape and are manufactured in the Boston Foundation’s state-of-the-art lab. It can take several months of cus-

tomization to get the best fi t. Dr. Shorter and her team help to train patients on the devices which are removed at bedtime and re-inserted in the morning.

PROSE devices can solve a variety of eye problems. Pa-tients like Sheri Rapaport cannot see with spectacles and her PROSE devices aid her vision. Other patients might need them to permanently protect or temporarily heal the ocular surface due to injury.

Rapaport says Dr. Shorter has been a calming infl uence throughout her treatment. “It has been a real hopeful, pos-itive process from the beginning.” She adds, “Now I can go to the grocery store and see what is on the shelves…it’s like PROSE has given me my independence back.”

Even better, Rapaport said she can now clearly see her newborn grandchild. “It’s just been phenomenal.”

Even better, Rapaport said she can now clearly see her

newborn grandchild. “It’s just been phenomenal.”

8

Severe and chronic ocular injuries and diseases have long vexed ophthalmologists trying to find ways to accelerate healing and promote regeneration of the eye surface.

Stem cell research might finally provide an answer.

“We’ve never had very effective treatments for severe eye injuries and for chronic conditions where the corneal surface cannot regenerate itself,” says Ali Djalilian, MD, Associate Professor of Ophthalmology/Cornea Service. That’s why Djalilian, Director of the Infirmary’s Corneal Epithelial Biology and Tissue Engi-neering Laboratory, is researching ways to apply stem cell-produced factors – specialized proteins that can get diseased or injured cells to heal – as a topical treatment on the eye surface.

Djalilian anticipates that such stem cell-produced factors may be dis-pensed through eyedrops or by specialized contact lenses that lock the healing solution in place.

“We think this will be helpful for a wide range of patients with severe injuries or diseases of the surface of the eye,” says Djalilian of the 1 million dollar project, which launched about a year ago and is roughly two to three years away from human trials.

Stem cells are cultured in the Infirmary laboratory so such factors can be collected,” says Djalilian. To date, most of his studies have “been based on optimizing those conditions and testing them in animal models.” This summer, the De-partment’s team is hoping to begin pre-clinical studies that will eventually allow the U.S. Food and Drug Administration to give the Department clearance to start clinical trials.

Stem cell research is a very hot topic right now in oph-thalmology, but Djalilian says the Department provides a unique home for this new technology to flourish. “As a de-partment and a team, we are set up very well to translate

STEM CELLS AND SIGHTCan stem cell technology at the squeeze of an eyedropper promote healing and regeneration for the worst injuries and diseases of the eye surface?

this research to the clinic. We see the most difficult patients that no one else is able to take care of.”

He adds that “the Department of Ophthalmology has a long history of cultivating important research with the infra-structure to do top quality work.”

This particular project has been supported by the U.S. Department of Defense, which is seeking greater treatment options for eye injuries and combat-related conditions. Djalilian’s project is also being supported with a

grant from the Vision for Tomorrow Foundation, a Chicago-based organization that supports families affected by aniridia—an absence of the iris in one or both eyes, or albinism—a disorder that prevents the body’s ability to produce or distribute melanin.

Helen Mopsick, board member at Vision for Tomorrow, said the or-ganization connected with Djalilian in 2011 and supports the research

because current treatment for aniridia is a cornea trans-plant. Said Mopsick, “If this works, (Djalilian) will literally be changing the course of treatment for thousands of people. Part of the condition of aniridia is that if the cornea starts to deteriorate in someone’s late teens or early twenties, the injury just doesn’t heal.”

Mopsick added that Djalilian approached the foundation and a lab visit made it a partnership. “He has quite a few patients and we love finding researchers who are also in clinic,” she said. “This is our first project with [the Depart-ment of Ophthalmology at the Illinois Eye and Ear Infirma-ry], and it’s been a very good experience: very responsive. And we’ll be back.”

“If this works, (Djalilian) will literally be changing

the course of treatment for thousands of people.

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“As a department and a team, we are set up very well to translate this research to the clinic. We see the most diffi cult patients that no one else is able to take care of.”

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CORNEA AND REFRACTIVE SURGERYThe Cornea and External Disease Service manages pa-

tients with diseases of the front of the eye including corneal

and conjunctival infections, keratoconus, cataracts, tumors

of the iris and conjunctiva, blepharitis, dry eye, corneal scar-

ring, complications of trauma and ocular surgery as well as

hereditary corneal diseases like Fuchs’ Dystrophy. The ser-

vice has extensive expertise in all forms of partial thickness

corneal transplantation including DMEK, DSAEK/ DSEK,

and DALK as well as traditional penetrating keratoplasty that

provides patients with the widest array of treatment options.

Those not eligible for human corneal transplantation may

qualify for our Artificial Cornea Program, which is the largest

program of its kind in the Midwest for implanting keratopros-

theses. The service also provides access to state-of-the-art

imaging technology to quickly and accurately diagnose a

wide spectrum of diseases. Cornea specialists also work

with the Contact Lens Service to offer advanced contact

lens therapies including the PROSE lens and offer the op-

portunity to participate in the latest clinical trials for dry eye

diseases, corneal transplantation and corneal infections.

DIRECTOR Elmer Y. Tu, MDProfessor of Clinical OphthalmologyDirector, Cornea Service

MEDICAL SCHOOLUniversity of Miami

RESIDENCY IN OPHTHALMOLOGYUniversity of Wisconsin

CLINICAL FELLOWSHIPBascom Palmer Eye Institute (Cornea)

Clinical InterestsCorneal transplantation including DMEK, DSAEK, DALK and Full thickness corneal transplantation; Corneal infections and corneal inflammatory disorders; Complex and routine cataract surgery

Research InterestsCorneal infections and inflammation; Corneal transplantation; New surgical and drug therapies

IMAGE: Photo of iris and pupil courtesy of the Eye Photography Service.

OneVision | 11CORNEA SERVICE continued on next page

Dimitri T. Azar, MD, MBADean, University of Illinois College of MedicineDistinguished Professor of Ophthalmology, Bioengineering and PharmacologyB.A. Field Chair in Ophthalmologic Research

MEDICAL SCHOOLAmerican University of Beirut, Lebanon

RESIDENCY IN OPHTHALMOLOGYMassachusetts Eye and Ear Infi rmary

CLINICAL FELLOWSHIPMassachusetts Eye and Ear Infi rmary (Cornea)

RESEARCH FELLOWSHIPSchepens Eye Research Institute

GRADUATE SCHOOLUniversity of Chicago (MBA)

Clinical Interestslaser vision correction; cornea and cataract surgery

Research InterestsMatrix metalloproteinases in corneal wound healing and angiogenesis; Refractive surgery; Optics; Accommodating intraocular lenses

M. Soledad Cortina, MDAssistant Professor of OphthalmologyDirector, Comprehensive Ophthalmology Faculty Practice (COFP) and General Eye ClinicDirector, Artifi cial Cornea Program

MEDICAL SCHOOLUniversity of Buenos Aires School of Medicine, Argentina

RESIDENCY IN OPHTHALMOLOGYLouisiana State University

CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Cornea)

RESEARCH FELLOWSHIPLouisiana State University, Neuroscience Center

Clinical InterestsOcular surface disease and high-risk corneal transplantation including Boston keratoprosthesis; Cataract surgery and endothelial keratoplasty

Research InterestsSterile keratolysis in Boston keratprosthesis patients; Optical properties of artifi cial corneas; Corneal nerves and their regeneration after injury

Jose de la Cruz, MDAssistant Professor of OphthalmologyCo-Director, Millennium Park Eye Center

MEDICAL SCHOOLPonce School of Medicine, Puerto Rico

RESIDENCY IN OPHTHALMOLOGY New York Eye and Ear Infi rmary


GRADUATE SCHOOLIndiana University at Bloomington (MS)

Clinical InterestsAdvances in keratoprosthesis transplantation; Anterior segment imaging in cornea and refractive surgery; Femtosecond technology for corneal tranplantation

Research InterestsDevelopment of surgical devices for conjunctival manipulation; New techniques in refractive surgery and femtosecond assisted keratoplasty; Advanced technology intraocular lenses for correction of presbyopia and astigmatism

Ali R. Djalilian, MDAssociate Professor of OphthalmologyDirector, Corneal Epithelial Biology and Tissue Engineering Laboratory

MEDICAL SCHOOLUniversity of Minnesota

RESIDENCY IN OPHTHALMOLOGYUniversity of Minnesota

CLINICAL FELLOWSHIPCincinnati Eye Institute (Cornea)

RESEARCH FELLOWSHIPUniversity of Minnesota (Cornea)

RESEARCH FELLOWSHIPNational Eye Institute (Ocular Immunology)

Clinical InterestsOcular surface disease; Limbal stem cell defi ciency; Corneal and limbal stem cell transplantation; Immunologic diseases of the cornea

Research InterestsStem cell based therapy; Corneal wound healing; Tissue engineering

Sandeep Jain, MDAssociate Professor of OphthalmologyDirector, Corneal Neurobiology LaboratoryDirector, Dry Eye Service

MEDICAL SCHOOLUniversity of Delhi, India

RESIDENCY IN OPHTHALMOLOGYHarkness Eye Institute


RESEARCH FELLOWSHIPWilmer Eye Institute (Cornea)

Clinical InterestsDry Eye and Ocular surface disease; Ocular graft-versus-host-disease; Neurotrophic keratitis

Research InterestsMolecular and cellular aspects of corneal nerve regeneration; Molecular and cellular aspects of ocular surface disease; Translational research

Mark I. Rosenblatt, MD, PhD, MBAProfessor and HeadDepartment of Ophthalmology & Visual SciencesIllinois Lions/Charles I. Young Chair in Ocular ResearchDirector, Corneal Regenerative Medicine Laboratory

MEDICAL SCHOOLUniversity of Miami (PhD, Biochemistry)




GRADUATE SCHOOLNew York University (MBA)

Clinical InterestsCorneal disease; Cataract; Refractive surgery; Ocular pain; Dry Eye disease; Keratoplasty

Research InterestsOcular regenerative medicine; Corneal stem cells; Corneal nerve regeneration; Angiogenesis; Tissue engineering; Biomaterials; Nanomedicine

12

Joel Sugar, MDJoel Sugar MD Professor in OphthalmologyVice Chair, Clinical Operations

MEDICAL SCHOOLUniversity of Michigan

RESIDENCY IN OPHTHALMOLOGYWashington University, St. Louis

CLINICAL FELLOWSHIPUniversity of Florida, Gainesville (Cornea)

Clinical InterestsCorneal disorders; Herpes simplex; Herpes zoster; Congenital anomalies of the anterior eye

Research InterestsKeratoplasty outcomes; Herpes; Fuchs dystrophy

Charles Qian Yu, MDAssistant Professor of Ophthalmology

MEDICAL SCHOOLUniversity of California Davis

RESIDENCY IN OPHTHALMOLOGYStanford University

CLINICAL FELLOWSHIP (CORNEA)Cornell University

Clinical InterestsCataract; Penetrating keratoplasty; Endothelial keratoplasty; Keratoprosthesis

Research InterestsCorneal healing; Artificial cornea; LASIK clinical trials; Virtual reality

CORNEA AND REFRACTIVE SURGERY (CONT.)

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Timothy T. McMahon, OD, FAAOProfessor of OphthalmologyVice Chair for Optometry

OPTOMETRY SCHOOLIllinois College of Optometry

RESIDENCY IN OPTOMETRYKansas City VA Medical Center

Clinical InterestsMedically necessary contact lenses; Corneal topography; Anterior segment diseases and injuries

Research InterestsKeratoconus and other corneal ectactic conditions and diseases; Dry eye; Blepharitis

DIRECTOR Charlotte E. Joslin, OD, PhD, FAAOAssociate Professor of OphthalmologyDepartment Affi liate, Epidemiology and BiostatisticsDirector, Contact Lens Service

OPTOMETRY SCHOOLOhio State University College of Optometry

RESIDENCY IN OPTOMETRYJesse Brown VA Medical Center andBlind Rehabilitation Center of Hines VA Hospital

GRADUATE SCHOOLUniversity of Illinois at Chicago (PhD, Epidemiology)

Clinical InterestsMedically necessary contact lenses for diseases such as: Keratoconus; Post-corneal transplant; Dry eye; Graft-versus-host disease (GVHD); Limbal stem cell defi ciency, Sjögren’s syndrome, Neurotrophic keratitis; Corneal scarring; Stevens-Johnson syndrome; Post-LASIK

Research InterestsEpidemiology of various eye diseases and infections; Racial differences in various eye and other health-related outcomes

Ellen Shorter, OD, FAAOAssistant Professor of OphthalmologyDirector, Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) Clinic


RESIDENCY IN OPTOMETRYJesse Brown VA Medial Center and Hines VA Hospital

CLINICAL FELLOWSHIPBoston Foundation for Sight (PROSE)

Clinical InterestsOcular surface disease; Corneal ectasia; Keratoconus; Keratoprosthesis

Research InterestsDry eye; Adenoviral conjunctivitis

CONTACT LENSThe Contact Lens Service provides care to patients requiring medically necessary contact lenses and related services.

Our doctors are nationally known for their clinical and research expertise and their ability to help patients with various

complex corneal diseases including: Keratoconus, Post-corneal transplant, Dry eye syndrome, Graft-versus-host disease

(GVHD), Limbal stem cell defi ciency, Sjögren’s syndrome, Neurotrophic keratitis, Corneal scarring, Stevens-Johnson

syndrome, Post-LASIK, and Aphakia. We have extensive experience with all types of medically necessary contact lenses

including scleral, hybrid and rigid contact lenses as well as customized soft contact lenses. The service’s PROSE clinic

is one of only 12 clinic sites in America to offer BostonSight® PROSE treatment for patients with severely compromised

ocular function as a result of complex corneal disease.

###

14

GLAUCOMA

Glaucoma is the leading cause of irreversible blind-

ness in the world. Our Glaucoma Service is nationally

recognized as a center for the diagnosis and treat-

ment of glaucoma in adults and children. It is a site

for testing investigational new drugs and has been

a leader in the use of laser and surgery to treat all

forms of the disease. Our service offers comprehen-

sive care and management of all forms of glaucoma,

including specialized diagnostic testing and the latest

technologies for laser and surgical treatment. Faculty

members are actively involved in glaucoma research

and are nationally recognized as experts in their fi eld.

DIRECTOR Thasarat S. Vajaranant, MDAssociate Professor of OphthalmologyDirector, Glaucoma Service

MEDICAL SCHOOLChulalongkorn University, Thailand

RESIDENCY IN OPHTHALMOLOGYIllinois Eye and Ear Infi rmary

CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Glaucoma)

RESEARCH FELLOWSHIPIllinois Eye and Ear Infi rmary (Low Vision)

Clinical InterestsDiagnosis and management of glaucoma and cataract; Management of complex glaucoma and cataract; International ophthalmology

Research InterestsGlaucoma epidemiology; Women’s eye health; Aging of the optic nerve; Outcomes of glaucoma surgery; Management of glaucoma after corneal transplants

IMAGE: Fundus photo highlighting optic nerve of glaucoma patient courtesy of the Glaucoma Service.

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Ahmad A. Aref, MDAssistant Professor of Ophthalmology

MEDICAL SCHOOLNorthwestern University

RESIDENCY IN OPHTHALMOLOGYPenn State Hershey Eye Center

CLINICAL FELLOWSHIPBascom Palmer Eye Institute (Glaucoma)

Clinical InterestsComplex cataract surgery; Trabeculectomy and glaucoma drainage implant surgery for advanced glaucomatous disease; Microinvasive glaucoma surgery for mild/moderate glaucomatous disease; Selective laser trabeculoplasty for open-angle glaucomas; Laser iridotomy for angle-closure glaucomas

Research InterestsSurgical techniques in complex glaucomas; Risk factor analysis of steroid-response glaucoma; Glaucoma associated with retinal disorders; Novel glaucoma medical therapies; Optic nerve imaging

Jacob T. Wilensky, MDJacob T. Wilensky MD Professor of OphthalmologyDirector, Glaucoma Fellowship Program

MEDICAL SCHOOLTulane University

RESIDENCY IN OPHTHALMOLOGYTulane University Affi liated Hospitals

CLINICAL FELLOWSHIPWashington University, St. Louis (Glaucoma)

RESEARCH FELLOWSHIPNational Eye Institute (Glaucoma)

Clinical InterestsDiagnosis and treatment of glaucoma with special emphasis on laser therapy

Research InterestsInvestigation of new drugs for glaucoma; Laser therapy treatment for glaucoma

OTHER CLINICAL FACULTY

David S. Hillman, MDAssistant Professor of Clinical Ophthalmology

Mark W. Lunde, MDAssistant Professor of Clinical Ophthalmology

16

NEURO-OPHTHALMOLOGY

The Neuro-Ophthalmology Service offers expert

evaluations and treatment for neuro-ophthalmo-

logic conditions, including: optic neuritis, idiopathic

intracranial hypertension (pseudotumor cerebri),

ischemic optic neuropathies, optic neuropathies of

unknown etiology, ocular myasthenia gravis, cranial

nerve palsies, thyroid eye disease and visual or oc-

ulomotor complications of stroke, brain tumors, mul-

tiple sclerosis and other neurological diseases. The

service facilitates and interprets a wide range of diag-

nostic testing relevant to the diagnosis and manage-

ment of neuro-ophthalmic diseases, including: Gold-

mann and Humphrey perimetry, infrared pupilometry,

optical coherence tomography, electroretinography,

lumbar punctures and magnetic resonance imaging.

The service works closely with doctors in the Univer-

sity of Illinois Hospital and Health Sciences Systems’

departments of Neurosurgery, Neurology, Radiation

Oncology and Rheumatology to provide interdisci-

plinary, state-of-the-art treatments.

DIRECTOR Heather E. Moss, MD, PhDAssistant Professor of OphthalmologyDirector, Neuro-Ophthalmology ServiceDirector, Neuro-Ophthalmology Fellowship Program

MEDICAL SCHOOLHarvard Medical School

RESIDENCY IN NEUROLOGYUniversity of Pennsylvania

CLINICAL FELLOWSHIPUniversity of Pennsylvania (Neuro-Ophthalmology)

GRADUATE SCHOOLHarvard-MIT Division of Health Sciences and Technology (PhD, Medical Engineering)

Clinical InterestsIdiopathic intracranial hypertension; Optic neuritis; Optic neuropathies; Optic chiasm disorders; Visual disorders with neurological causes; Ocular myasthenia gravis; Cranial nerve palsies

Research InterestsIdiopathic intracranial hypertension; Optic neuritis; Visual system dysfunction in amyotrophic lateral sclerosis

IMAGE: Brain MRI depicting orbital structures courtesy of iStock.

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James Goodwin, MDAssociate Professor of Ophthalmology

MEDICAL SCHOOLUniversity of Illinois College of Medicine

RESIDENCY IN NEUROLOGYUniversity of Minnesota

CLINICAL FELLOWSHIPBascom Palmer Eye Institute (Neuro-Ophthalmology)

Clinical InterestsOptic neuritis; Optic neuropathies; Ophthalmoplegia; Visual fi eld loss; Idiopathic intracranial hypertension; Cranial nerve palsies

Research InterestsOptic neuritis; Autoimmune optic neuropathy; Optic nerve decompression

Peter W. MacIntosh, MDAssistant Professor of Ophthalmology

MEDICAL SCHOOLThe Chicago Medical School

RESIDENCY IN OPHTHALMOLOGYStroger Cook County Hospital

CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Neuro-Ophthalmology)

CLINICAL FELLOWSHIPMassachusetts Eye and Ear Infi rmary (Oculoplastics)

Clinical InterestsIdiopathic intracranial hypertension; Diplopia; Ptosis; Eyelid and orbital tumors; Orbital trauma

Research InterestsThyroid eye disease; Nonarteritic anterior ischemic optic neuropathy (NAION)


Anil Gulati, MDAssistant Professor of Clinical Ophthalmology

18

OCULOPLASTIC & RECONSTRUCTIVE SURGERYThe Oculoplastic & Reconstructive Surgery Service

provides assessment and treatment for conditions of

the eyelids, orbit, face and lacrimal system. Systemic

disease, trauma, birth defects and the aging process

can alter the area around the eyes. Conditions such

as blepharoptosis, ectropion, entropion, eyelid retrac-

tion, blepharospasm, epiphora, tumors of the ocular

adnexa and orbit and fractures of the orbit are just a

few of the conditions treated in this specialty. Patients

can be seen at both the Illinois Eye and Ear Infirmary

and the Millennium Park Eye Center.

DIRECTOR Pete Setabutr, MDAssociate Professor of OphthalmologyDirector, Oculoplastic & Reconstructive Surgery ServiceCo-Director, Millennium Park Eye Center

MEDICAL SCHOOLUniversity of Texas-Houston

RESIDENCY IN OPHTHALMOLOGYUniversity of Texas-Houston

CLINICAL FELLOWSHIPIllinois Eye and Ear Infirmary (Oculoplastics)

Clinical InterestsCosmetic and reconstructive eyelid surgery; Orbital surgery; Diseases of the lacrimal system

Research InterestsDiseases of the eyelid; Diseases of the orbit; Epidemiological international vision research

IMAGE: Artistic rendering of a human skull courtesy of Lisa Birmingham.

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Vinay K. Aakalu, MD, MPHAssistant Professor of OphthalmologyDirector, Lacrimal Cell Biology Laboratory

MEDICAL SCHOOLMount Sinai School of Medicine


CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Oculoplastics)

GRADUATE SCHOOLColumbia University (MPH)

Clinical InterestsThyroid eye disease; Orbital tumors; Facial and ocular trauma; Ocular surface disease and scarring; Infl ammatory orbital disease; Congenital eyelid and orbital disorders; Eye socket reconstruction; Facial palsies; Eyelid malposition; Lacrimal disease; Aesthetic surgery and treatments

Research InterestsRegenerative medicine; Lacrimal cell biology; Dry eye disease; Cell based therapies; Orbital imaging; Orbital oncology; Novel and minimally invasive orbital and aesthetic surgery

Allen M. Putterman, MD, FACSProfessor of Ophthalmology

MEDICAL SCHOOLUniversity of Wisconsin

RESIDENCY IN OPHTHALMOLOGYMichael Reese Hospital and Medical Center

CLINICAL FELLOWSHIPManhattan Eye, Ear and Throat Hospital (Oculoplastics)

Clinical InterestsAesthetic eyelid and facial plastic surgery; Upper eyelid ptosis surgery; Thyroid eyelid and orbital problems; Eyelid and orbital tumors; Tear duct drainage surgery

Research InterestsDevelopment of procedures and instruments for oculofacial plastic surgery

Amjad Z. Ahmad, MDAssistant Professor of Clinical Ophthalmology

MEDICAL SCHOOL University of Michigan

RESIDENCY IN OPHTHALMOLOGY Kellogg Eye Institute

CLINICAL FELLOWSHIP Kellogg Eye Institute (Oculoplastic & Reconstructive Surgery)

CLINICAL INTERESTS Cosmetic eyelid surgery; Thyroid eye disease; Eyelid reconstruction surgery; Ptosis

RESEARCH INTERESTS Cosmetic eyelid surgery

Peter W. MacIntosh, MDAssistant Professor of Ophthalmology

MEDICAL SCHOOLThe Chicago Medical School

RESIDENCY IN OPHTHALMOLOGYStroger Cook County Hospital

CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Neuro-Ophthalmology)

CLINICAL FELLOWSHIPMassachusetts Eye and Ear Infi rmary (Oculoplastics)

Clinical InterestsLacrimal drainage surgery; Ptosis

Research InterestsThyroid eye disease; Nonarteritic anterior ischemic optic neuropathy (NAION)

20

PEDIATRIC OPHTHALMOLOGY & ADULT STRABISMUS

The Pediatric Ophthalmology & Adult Strabismus

Service offers general pediatric eye care, including

exams for newborns and children up to 18 years of

age. This service also provides other specialty clinics

treating rare and unusual children’s eye disorders, in-

cluding glaucoma and genetic, neurocutaneous, and

neuro-ophthalmologic disorders. The doctors in this

service specialize in strabismus (eye alignment dis-

orders) in adults as well as children. Additional care

providers include certified orthoptists and an ocu-

loplastic and reconstructive surgeon.

DIRECTOR Nathalie F. Azar, MDAssociate Professor of Clinical OphthalmologyDirector, Pediatric Ophthalmology & Adult Strabismus Service

MEDICAL SCHOOLBoston University

RESIDENCY IN OPHTHALMOLOGYGeorge Washington University

CLINICAL FELLOWSHIPWilmer Eye Institute (Pediatric Ophthalmology)

Clinical InterestsAdult strabismus; Graves ophthalmopathy; Paralyticand restrictive strabismus; Amblyopia; Pediatric strabismus, cataracts and glaucoma

Research InterestsAmblyopia; Eye movement disorders; Surgical treatment techniques for strabismus; Pediatric ocular anomalies

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Benjamin Mathew, MDAssistant Professor of Clinical Ophthalmology

MEDICAL SCHOOL University of Manitoba

RESIDENCY IN OPHTHALMOLOGY LSU Eye Center/ Alton Ochsner Clinic Foundation University of Ottawa Eye Institute

RESEARCH FELLOWSHIP University of Ottawa Eye Institute (Ophthalmic Pathology)

CLINICAL FELLOWSHIP University of Wisconsin (Pediatric Ophthalmology)

Clinical Interests General pediatric ophthalmology; Pediatric cataract; Blocked tear duct; Retinopathy of prematurity

Research Interests Ophthalmic optics; Automated measurement of strabismus

IIrene H. Maumenee, MDResearch Professor of OphthalmologyDirector, Ocular Genetics Laboratory

MEDICAL SCHOOLUniversity of Göttingen, Germany

RESEARCH FELLOWSHIPSUniversity of Geneva (Ophthalmology and Genetics)University of Hawaii (Population Genetics)Johns Hopkins University (Medical Genetics)

PRECEPTORSHIP IN OPHTHALMOLOGYWilmer Eye Institute

Clinical InterestsManagement of complications of the Marfan syndrome and related connective tissue diseases; Clinical diagnosis of patients with rare genetic diseases of the visual system

Research InterestsFinding new genes and mutations in hereditary eye diseases through application of whole exome and whole genome sequencing strategies; Special interest in Leber congenital amaurosis

Marilyn T. Miller, MD, MSProfessor of Ophthalmology

MEDICAL SCHOOLUniversity of Illinois College of Medicine, Chicago


CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary and Cook County Hospitals (Strabismus)

GRADUATE SCHOOLUniversity of Illinois at Chicago (MS, Microbiology)

Clinical InterestsInternational ophthalmology with special interest in training issues in pediatric ophthalmology; Craniofacial syndromes; Teratology; Duane syndrome

Research InterestsTeratology: craniofacial anomalies; Duane syndrome

SPECIALTY FACULTY


Vinay K. Aakalu, MD, MPHOculoplastic and Reconstructive Surgery

R.V. Paul Chan, MD, MSc, FACSPediatric Retina

Felix Y. Chau, MDPediatric Retina

Kimberlee Curnyn, MDAssistant Professor of Clinical Ophthalmology

Lawrence Kaufman, MD, PhDAssociate Professor of Clinical Ophthalmology

Ben Ticho, MDAssociate Professor of Clinical Ophthalmology

Javaneh Abbasian, MDAssistant Professor of Ophthalmology

22

RETINAThe Retina Service specializes in treating patients

with both medical and surgical retinal vascular and

vitreoretinal disorders, such as: age-related macular

degeneration, vein occlusion, sickle cell eye disease,

ocular complications of diabetes, retinal detachment,

vitreomacular adhesion, retinopathy of prematurity,

retinitis pigmentosa, intraocular tumors and severe

eye trauma. The doctors in this service are skilled

specialists in laser and other medical treatment of

the retina, vitreoretinal surgery and complex retinal

detachment repair.

DIRECTOR Jennifer I. Lim, MD, FARVOMarion H. Schenk Esq Chair in Ophthalmology for Research of the Aging EyeProfessor of OphthalmologyDirector, Retina Service


RESIDENCY IN OPHTHALMOLOGYIllinois Eye and Ear Infirmary

CLINICAL FELLOWSHIPWilmer Eye Institute (Retina)

Clinical InterestsDiabetic retinopathy; Age-related macular degeneration; Retinal vascular diseases; Macular diseases; Retinal detachments and vitreoretinal disorders; Ocular tumors; Retinal degenerations

Research InterestsMedical and surgical treatments; Clinical trials to evaluate new medical and surgical treatments of retinal diseases; Retinal imaging as applied to management of retinal diseases and determination of pathophysiology; Collaborative projects with basic scientists on pathogenesis of retinal diseases

IMAGE: Immunofluorescence image of retinal cell layers courtesy of the Vitreoretinal Microsurgery Laboratory.

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Norman P. Blair, MDProfessor of OphthalmologyDirector, Laboratory of Retinal Circulation and Metabolism

MEDICAL SCHOOLIndiana University

RESIDENCY IN OPHTHALMOLOGYMassachusetts Eye & Ear Infi rmary

CLINICAL FELLOWSHIPRetina Associates/Massachusetts Eye & Ear Infi rmary (Retina)

CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Ophthalmic Pathology)


Research InterestsRetinal oxygenation; Retinal energy metabolism; Retinal blood fl ow and ischemia; Diabetic retinopathy

Felix Y. Chau, MDAssistant Professor of OphthalmologyDirector, Retinal Bioengineering Laboratory

MEDICAL SCHOOLUniversity of Iowa

RESIDENCY IN OPHTHALMOLOGYDuke University Eye Center

CLINICAL FELLOWSHIPIllinois Eye and Ear Infi rmary (Retina)

Clinical InterestsPediatric and adult retinal diseases; Retinopathy of prematurity (ROP); Retinoblastoma; Rare congenital and inherited retinal diseases; Proliferative vitreoretinopathy (PVR); Diabetic retinopathy; Macular degeneration; Cystoid macular edema

Research InterestsMedical and surgical treatments; Experimental models and risk factors for retinal diseases; Engineering applications in ophthalmology

Yannek I. Leiderman, MD, PhDAssistant Professor of OphthalmologyDirector, Vitreoretinal Microsurgery Laboratory

MEDICAL SCHOOLGeorge Washington UniversityNational Institutes of Health Partnership (PhD, Molecular Pathobiology)


CLINICAL FELLOWSHIPMassachusetts Eye and Ear Infi rmary (Vitreoetinal Surgery)

Clinical InterestsVitreoretinal surgical diseases; Diabetic eye disease; Complex retinal detachment; Proliferative vitreoretinopathy (PVR); Macular surgery; Treatment of aphakia and placement of secondary intraocular lenses

Research InterestsEffectiveness of ophthalmic surgical interventions in diseases of the retina and vitreous; High-fi delity modeling of novel surgical devices and experimental techniques in microsurgery

William F. Mieler, MD, FARVOCless Family Professor in OphthalmologyVice Chair for EducationDirector, Ocular Oncology ClinicDirector, Residency and Vitreoretinal Fellowship Training

MEDICAL SCHOOLUniversity of Wisconsin-Madison

RESIDENCY IN OPHTHALMOLOGYBascom Palmer Eye Institute

CLINICAL FELLOWSHIPThe Eye Institute, Medical College of Wisconsin (Retina-Vitreous)

CLINICAL FELLOWSHIPWills Eye Hospital (Ocular Oncology)

Clinical InterestsDiseases of the macula, retina and vitreous; Age-related macular degeneration; Diabetic macular edema; Venous occlusive diseases; Vitreoretinal interface disorders; Ocular oncology

Research InterestsOcular pharmacology; Intraocular tumors; Ocular imaging

Lawrence J. Ulanski, MD, IIAssistant Professor of Clinical Ophthalmology

MEDICAL SCHOOLUniversity of Michigan

RESIDENCY IN OPHTHALMOLOGYWilliam Beaumont Eye Institute

CLINICAL FELLOWSHIPSUniversity of Toronto, (Vitreo-Retina and Ocular Oncology)Illinois Eye and Ear Infi rmary (Uveitis)

R. V. Paul Chan, MD, MSc, FACSProfessor of OphthalmologyVice Chair for Global OphthalmologyCo-Director Vitreoretinal Fellowship Training Program

MEDICAL SCHOOLTemple University

RESIDENCY IN OPHTHALMOLOGYNew York-Presbyterian Hospital, Cornell University

CLINICAL FELLOWSHIP Massachusetts Eye and Ear Infi rmary (Retina)

Clinical Interests Adult and pediatric retinal disease including retinopathy of prematurity (ROP); Retinal vascular diseases; Eye trauma; Eye infections/endophthalmitis; Diabetic retinopathy; Age-related macular degeneration

Research Interests Global ophthalmology; Telemedicine and tele-education; New methods of diagnosing and managing pediatric retinal disease

24

UVEITISUveitis causes up to 20 percent of blindness in the United States. The Uveitis Service treats patients with inflammation of

the uveal tract, the middle vascular layers of the eye critical to its normal function. Because of the rich circulation of blood

throughout this area and its proximity to other important parts of the eye, the uvea is susceptible to immune disorders.

Patients are referred to this service for the diagnosis and management of infectious and non-infectious ocular inflamma-

tory conditions such as scleritis and anterior, intermediate and posterior uveitis. Treatment with steroid-sparing systemic

immunomodulatory therapy is offered when appropriate. The service also performs procedures for its uveitis patients such

as the insertion of steroid eluting implants as well as surgical management of complex uveitic cataracts.

CO-DIRECTOR Pooja Bhat, MDAssistant Professor of OphthalmologyDirector, Uveitis Service

MEDICAL SCHOOLLokmanya Tilak Municipal Medical College and Hospital, India

RESIDENCY IN OPHTHALMOLOGYNorthwestern University

CLINICAL FELLOWSHIPSNorthwestern University (Uveitis)Massachusetts Eye and Ear Infirmary (Ophthalmic Pathology)

RESEARCH FELLOWSHIPMassachusetts Eye Research and Surgery Institution (Uveitis)

Clinical InterestsScleritis; Anterior, intermediate and posterior uveitis; Vogt-Koyanagi-Harada (VKH) disease; Behcet’s syndrome; Sarcoidosis; Infectious retinopathies; White dot syndromes

Research InterestsSystemic immunosuppression for ocular inflammatory conditions; Seasonal variations in autoimmune diseases; Disc and scleral changes in VKH; Schisis in pars planitis; Anterior segment and posterior segment imaging with optical coherence tomography IMAGE: Colorized OCT image of VKH patient’s retina courtesy of the Uveitis

Service.

CO-DIRECTOR Ann-Marie Lobo, MD Assistant Professor of Ophthalmology

MEDICAL SCHOOLLouisiana State University New Orleans

RESIDENCY IN OPHTHALMOLOGYMassachusetts Eye and Ear Infirmary

CLINICAL FELLOWSHIP (OCULAR IMMUNOLOGY/UVEITIS)Massachusetts Eye and Ear Infirmary

Clinical InterestsOcular inflammatory disease, including infectious and non-infectious uveitis, scleritis and ocular surface inflammation; Cataract surgery

Research InterestsDiagnostic testing in infectious and non-infectious uveitis; Outcomes of biologic response modifier therapies in the treatment of uveitis; Morbidity of childhood uveitis; Systemic infections and eye disease

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LOW VISION PATHOLOGYThis specialized service introduces patients with low

vision to technology and techniques to enhance their

remaining sight and facilitate their independence. A

low-vision optometrist and a certifi ed low-vision ther-

apist work as a team to provide clinical examination

and visual skills assessment. Therapies include spe-

cial optical and electronic devices, ergonomic equip-

ment and new visual skills training to address routine

daily tasks such as reading, writing, managing medi-

cation, cooking, locating and sign reading.

The Ophthalmic Pathology Laboratory is a joint pro-

gram of the Departments of Pathology and Ophthal-

mology that provides diagnostic services to patients

and physicians within and outside Illinois. The labora-

tory is integrated with the other clinical laboratories in

the University of Illinois Hospital and Health Sciences

System, making it possible to utilize the latest cut-

ting-edge diagnostic techniques in immunopathology

and molecular pathology available in the diagnosis of

ocular disorders.

DIRECTOR Joan A. Stelmack, OD, MPHAssociate Professor of Clinical OphthalmologyDirector, Low Vision Service


GRADUATE SCHOOLJohns Hopkins University (MPH)

Clinical InterestsRehabilitation of patients with vision loss

Research InterestsCreating multicenter clinical trials and observational studies to evaluate rehabilitation strategies and devices to restore or enhance vision

DIRECTOR Amy Y. Lin, MDAssistant Professor of Ophthalmology and PathologyDirector, Ophthalmic Pathology Laboratory

MEDICAL SCHOOLJohns Hopkins University

RESIDENCYIllinois Eye and Ear Infi rmary (in Ophthalmology)University of Illinois College of Medicine (in Pathology)

CLINICAL FELLOWSHIP (OPHTHALMIC PATHOLOGY)Illinois Eye and Ear Infi rmary

Clinical InterestsEye pathology; Pathologic basis of ophthalmic disease

Research InterestsOcular oncology; Pathology education; Virtual microscopy for learning pathology; Team-based learning

26

GENERAL EYE CLINIC (GEC)

The Comprehensive Eye Clinic is a premiere ophthalmology

practice run by recognized Board Certifi ed ophthalmologists.

The clinic provides: comprehensive eye exams, eyeglass pre-

scriptions and contact lens fi tting. The more extensive ser-

vices include: state-of-the-art cataract surgery, femtosecond

laser assisted cataract surgery, premium intraocular lenses

and the management of common and complex eye diseases.

Same-day or next-day appointments are available.

COMPREHENSIVE OPHTHALMOLOGY FACULTY PRACTICE (COFP)

The General Eye Clinic is the heart of our department

and serves as the fi rst point of contact for many of the

Infi rmary’s neediest patients, as well as a primary loca-

tion for ophthalmic graduate medical education. Our ded-

icated residents and world-class faculty provide a wide

spectrum of collaborative ophthalmic care ranging from

managing common eye diseases and delivering routine

eye exams to performing complex medical and surgical

cases including cataract, glaucoma and retinal proce-

dures. Special emphasis is placed on providing strong

continuity of patient care. The GEC sees emergent re-

ferrals from outside providers from throughout the region

and accepts “walk-in” patients with acute eye disease.

Sandeep Jain, MD (Cornea)

Ellen Shorter, OD, FAAO (Contact Lens)

Timothy McMahon, OD, FAAO (Contact Lens)

Jose de la Cruz, MD (Cornea)

Ali Djalilian, MD (Cornea)

Bryan Kim, MD(Cornea)

Anthony G. Finder, MDAssistant Professor of Clinical

Ophthalmology

MEDICAL SCHOOL Northwestern University

RESIDENCY IN OPHTHALMOLOGY Michael Reese Hospital and Medical Center

Clinical Interests General Ophthalmology; Early diagnosis and medical management of glaucoma; Analysis

of problems related to ophthalmic optics and refraction; Resident education

Ann-Marie Lobo, MD(Uveitis)

Peter Macintosh, MD(Neuro-Oph and Oculoplastics)

Mark Rosenblatt, MD, PhD, MBA (Cornea)

Joel Sugar, MD (Cornea)

Elmer Tu, MD (Cornea)

Charles Yu, MD (Cornea)

Ahmad Aref, MD(Glaucoma)

Pooja Bhat, MD (Uveitis)

DIRECTOR M. Soledad Cortina, MD (Cornea)Assistant Professor of OphthalmologyDirector, COFP and GECDirector, Artifi cial Cornea Program

GEC FACULTY

COFP FACULTY

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IMAGE: Cloud Gate sculpture in Chicago’s Millennium Park. Photographer: James Pharaon at iStock.

Timothy McMahon, OD, FAAO (Contact Lens)

William Mieler, MD (Retina)

MILLENNIUM PARK EYE CENTER (MPEC)

The Millennium Park Eye Cen-

ter (MPEC) is the conveniently

located city-center clinic of the

Illinois Eye and Ear Infi rmary.

Ophthalmologists and Optom-

etrists seeing patients at the

MPEC are all members of the

Department of Ophthalmolo-

gy & Visual Sciences faculty.

They diagnose and treat a

wide range of eye conditions

every day, from common eye

problems to the most complex

ophthalmic issues. The center

utilizes the most advanced eye

care technology in vision care

available, with state-of-the-art

diagnostic and surgical instru-

ments.

CO-DIRECTOR Jose de la Cruz, MD (Cornea)

CO-DIRECTOR Pete Setabutr, MD (Oculoplastic & Reconstructive Surgery)

Heather Moss, MD, PhD (Neuro-Ophthalmology)

Mark Rosenblatt, MD, PhD, MBA (Cornea)

R. V. Paul Chan, MD, MSc, FACS (Retina)

Ahmad Aref, MD(Glaucoma)

Dimitri Azar, MD, MBA (Cornea)

Nathalie Azar, MD(Pediatric Ophthalmology & Adult Strabismus)

28

RESEARCH FACULTY

Mahnaz Shahidi, PhDVice Chair and Research DirectorMorton F. Goldberg Professor of OphthalmologyProfessor of Physics and BioengineeringDirector, Applied Physics Laboratory

GRADUATE SCHOOLUniversity of Illinois at Chicago (MS, PhD, Atomic and Molecular Physics)

Research InterestsDevelopment and application of optical imaging systems for quantitative assessment of eye diseases, including diabetic retinopathy, age-related macular degeneration and sickle cell retinopathy

Dingcai Cao, PhDAssociate Professor of OphthalmologyDirector, Visual Perception Laboratory

GRADUATE SCHOOLBeijing University (MS, Biopsychology)University of Chicago (MS, Statistics)University of Chicago (PhD, Biopsychology)

Research InterestsMelanopsin-based visual perception and circadian rhythm; Rod-cone Interaction; Color perception; Retinal physiology; Lighting and health; Acute and chronic alcohol effect on vision and circadian rhythm

Xiaoyi “Raymond” Gao, PhDAssociate Professor of OphthalmologyDirector, Quantitative Ocular Genomics Laboratory

GRADUATE SCHOOLNorth Carolina State University (PhD, Bioinformatics-Statistics)

RESEARCH FELLOWSHIPSDuke University Center for Human Genetics Miami Institute for Human Genomics

Research InterestsOcular genomics; Glaucoma; Diabetic retinopathy; Age-related macular degeneration; Human genetics; Statistical genomics; Bioinformatics

The Department of Ophthalmology and Visual Sciences has a history of dedicated commitment and record of prominent

contributions to vision science research. The overarching goal for the research program is to address the significant chal-

lenges central to understanding, treating and preventing blinding eye disease. The program encompasses exemplary and

pioneering research in the most critical areas of vision research, including investigations to understand the mechanisms

of potentially blinding eye diseases, the development of innovative techniques and instruments for diagnosing and mon-

itoring the progression of eye diseases, genome-wide association studies, visual psychophysics, retinal processing, and

visual neurophysiology. The department maintains a tradition of excellence in collaborative and interdisciplinary research

that has advanced knowledge in basic vision science and facilitated translation of findings to improve clinical care of pa-

tients with eye diseases.

IMAGE: OCT image with retinal layers delineated courtesy of the Applied Physics Laboratory.

OneVision | 29

Joelle A. Hallak, PhD Assistant Professor of Ophthalmology Executive Director, Ophthalmology Center for Clinical Trials and Translational Studies

GRADUATE SCHOOL University of Illinois at Chicago (MS, PhD, Epidemiology)

Research Interests Ocular epidemiological research; Mental health; biological and genetic markers; Comparative effectiveness research and statistical analysis of complex data

Nalin M. Kumar, DPhilProfessor of Ophthalmology

GRADUATE SCHOOLUniversity of Oxford, UK (DPhil Biochemistry)

RESEARCH FELLOWSHIPBaylor College of Medicine (Cell and Molecular Biology)

Research InterestsIntercellular channels (gap junctions) and their involvement in the processes and mechanisms that are necessary for vision

J. Jason McAnany, PhDAssistant Professor of OphthalmologyDirector, Clinical Psychophysics and Electrophysiology Laboratory

GRADUATE SCHOOLUniversity of Illinois at Chicago (MA, PhD, Behavioral Neuroscience)

RESEARCH FELLOWSHIPUniversity of Illinois College of Medicine (Psychophysics and Electrophysiology)

Research InterestsElectroretinography; Psychophysics; Pupillometry; Retinal imaging; Acquired and inherited retinal disease

David R. Pepperberg, PhD, FARVOSearls-Schenk Professor of OphthalmologyDirector, Photoreceptor Research Laboratory

GRADUATE SCHOOLMassachusetts Institute of Technology (PhD, Biophysics)

RESEARCH FELLOWSHIPHarvard University (Vision Physiology)

Research InterestsDeveloping new molecular therapies that delay the progression of, and restore vision lost in, photoreceptor degenerative diseases such as age-related macular degeneration (AMD)

Deepak Shukla, PhDMarion H. Schenk Esq. Professor in Ophthalmology for Research of the Aging EyeProfessor of Ophthalmology, Microbiology and ImmunologyDirector, Ocular Virology Laboratory

GRADUATE SCHOOLUniversity of Illinois at Chicago (PhD , Microbiology and Immunology)

RESEARCH FELLOWSHIPNorthwestern University (Virology and Immunology)

Research InterestsOcular herpes virus infection mechanisms; Development of new therapeutic strategies against viral diseases of the aging eye; Herpes virus vaccine development

Xincheng Yao, PhDProfessor of Bioengineering and OphthalmologyDirector, Biomedical Optics and Functional Imaging Laboratory

GRADUATE SCHOOLHarbin Institute of Technology, China (MEng, Optical Instrumentation)Institute of Physics Chinese Academy of Sciences (PhD, Optics)

Research InterestsBiomedical optics; Retinal imaging; Experimental biophysics

30

Jin-Hong Robert Chang, PhDResearch Assistant Professor of OphthalmologyDirector, Angiogenesis Research Laboratory

GRADUATE SCHOOLUniversity of Mississippi (PhD, Biochemistry)

RESEARCH FELLOWSHIPUniversity of Virginia (Microbiology)

Research InterestsThe role of VEGFR1, R2 and R3 activity in vitro and in vivo with the broader goal of characterizing the intrinsic factors of lymphatic cells that regulate corneal angiogenesis and lymphangiogenesis; Development of targeted therapies for corneal injury and disease

Medi Eslani, MDResearch Assistant Professor of OphthalmologyCorneal Epithelial Biology and Tissue Engineering Laboratory

MEDICAL SCHOOLTehran University of Medical Sciences, Iran

RESEARCH FELLOWSHIPUniversity of Illinois College of Medicine (Biology and Tissue Engineering)

Research InterestsTranslational studies in ocular surface disease; Limbal stem cell deficiency; Refractive surgery; Clinical trials and population-based studies; Mesenchymal stem cell based therapy; Corneal innate immunity

Michael A. Grassi, MDResearch Associate Professor of Ophthalmology Director, Retinal Chemical Genomics Laboratory


RESIDENCY IN OPHTHALMOLOGYUniversity of Iowa

CLINICAL FELLOWSHIPUniversity of Iowa (Medical Retina)

RESEARCH FELLOWSHIPUniversity of Iowa (Molecular Ophthalmology)

Research InterestsImproving the treatment of retinal disease; Using cell-based models of retinal disease in genomic and chemical high throughput studies to identify key pathways and novel therapeutic targets

Victor H. Guaiquil, PhDAssistant Research Professor of Ophthalmology Corneal Regenerative Medicine Laboratory

GRADUATE SCHOOLUniversity Austral, Chile (MS)SUNY Downstate Medical Center, New York (PhD, Molecular and Cellular Biology)

RESEARCH FELLOWSHIPSMemorial Sloan-Kettering Cancer CenterHospital for Special Surgery, New York

Research InterestsCellular and molecular mechanisms involved in angiogenesis and neurogenesis in the retina and cornea; Cornea nerve regeneration; Oxygen induced retinopathy

Kyu Yeon Han, PhDResearch Assistant Professor of Ophthalmology Metalloproteinases Research Laboratory

GRADUATE SCHOOLSuwon University, Korea (MS, Genetic Engineering)Kyung Hee University, Korea (PhD, Oncology)

RESEARCH FELLOWSHIPUniversity of Illinois College of Medicine (Ophthalmology)

Research InterestsVascular angiogenesis in vitro and in vivo; The function of membrane type I metalloproteinase in cornea angiogenesis

RESEARCH FACULTY (CONTINUED)

Zeeshan Pasha, MD, PhD, MPHResearch Assistant Professor of Ophthalmology Corneal Regenerative Medicine Laboratory Lacrimal Cell Biology Laboratory

MEDICAL SCHOOLBahuddin Zakaryia University, Pakistan

GRADUATE SCHOOLUniversity of Punjab, Pakistan (PhD, Stem Cell Therapy)University of Illinois at Chicago (MPH)

RESEARCH FELLOWSHIPUniversity of Illinois at Chicago (Pharmacology)

Research InterestsStem cell based therapeutics; Induced pluripotent, adult and embryonic stem cells; Regenerative medicine; Small molecules; Angiogenesis; Drug screening; Clinical Trials; Translational research

OneVision | 31

ADJUNCT FACULTY

Norma Allemann, MD

Wallace Chamon, MD

Molly Gilbert, MD

Charles Kinnaird, OD

Paul Knepper, MD, PhD

Anthony Peter Adamis, MDEric C. Beyer, MD, PhDMichael Cho, PhDLisa Ebihara, MD, PhDGerald Fishman, MDRobert Folberg, MDCraig Foster, PhDDavid Freedman, PhDKen-Ichiro Fukuchi, MD, PhDRichard A. Gemeinhart, PhDDebra Goldstein, MDJohn R. Hetling, PhDYulia Komarova, PhDJie Liang, PhDKirk Packo, MD Robert Paul Malchow, PhD

Asrar Malik, PhDSekhar Reddy, PhDDaniel Roberts, OD, PhDSteven Roth, MDAlfred Rosenbloom, ODWilliam H. Seiple, PhDMichael Shapiro, MDMurray Sherman, PhDSatoru Suzuki, PhDJanet P. Szlyk, PhDHoward Tessler, MDVaibhav Tiwari, PhDKimani Toussaint, PhDKazuo Tsubota, MDXiaojing Yang, PhD

Daniel Alter, MD, PhDDavid Badawi, MDAdrienne Berman, MDHarit Bhatt, MDMichael Blair, MDRebekah Braslow, MDVictoria Butcko, ODRobert Egel, MDSteven Eiden, ODTimothy Flood, MDEnrique Garcia-Valenzuela, MDJon Gieser, MDDaniel Greenberg, MDJingtao Guo, MDRama Jager, MD, MBAKatherine Hare, MDBruce Kaplan, MDManali D. Kalra, MDYuri Kim Kerns, MDBryan Kim, MD

Spero Kinnas, MDTimothy Kisla, DOSheridan Lam, MDJanet Lee, MDDavid Lubeck, MDSmajo Osmanovic, MDAnna Park, MDRakhi Patil, MDMichael Paxhia, MDRichard Quinones, MDPervez Rasul, MDKenneth Resnick, MDAlfred Rosenbloom, ODVeeral Sheth, MDSriram Sonty, MDThomas Stelmack, ODDaniel Tepper, MDCharles Vygantas, MDRobert Weiss, MDChloe Winterbotham, MD

IMAGE: Immunofl uorescence image of conjunctival epithelium cells in ptosis surgical specimens courtesy of the Lacrimal Cell Biology Laboratory.

Joy Sarkar, PhDResearch Assistant Professor of Ophthalmology Corneal Neurobiology Laboratory

GRADUATE SCHOOLUniversity of Mumbai (MS, Microbiology)HN Hospital and Research Center, India (PhD, Biochemistry)

RESEARCH FELLOWSHIPSTata Institute of Fundamental Research, India (Biology)Northwestern University (Cellular and Molecular Biology)

Research InterestsMolecular and cellular aspects of dry eye disease; Innate immune mechanisms in dry eye; Role of neutrophil extracellular traps (NETS) and regulatory mechanisms in dry eye; Corneal nerve regeneration after injury

RESEARCH FACULTY (CONTINUED) AFFILIATED & JOINT COURTESY FACULTY

CLINICAL VOLUNTEER FACULTY

32

FEDERALLY SPONSORED GRANTS

INVESTIGATOR PROJECT TITLE FUNDING SOURCE

Vinay Aakalu, MD, MPH Study of Accessory Lacrimal Gland and Precursor Cell Biology National Eye Institute

Dimitri Azar, MD, MBA UIC K12 Independent Clinical Vision Scientist Development Program National Eye Institute

Dimitri Azar, MD, MBA Metalloproteinase Expression in Corneal Wound National Eye Institute

Dingcai Cao, PhD Alcohol Stimulations and Sedation in Binge Drinkers National Institute of Alcohol Abuse and Alcoholism *

Dingcai Cao, PhD Neural Stem Cell Based Virotherapy for Malignant Glioma National Institute of Neurological Disorders and Stroke*

Dingcai Cao, PhD Regulatory T Cells in Malignant Glioma National Cancer Institutes*

Dingcai Cao, PhD Rod-Cone Interactions in Mesopic Vision National Eye Institute

Jin-Hong Robert Chang, PhD Endostatin-derived Short Peptides in Corneal Transplantation Department of Veterans Affairs

Jin-Hong Robert Chang, PhD VEGFR2 modulates corneal angiogenesis and lymphangiogenesis National Eye Institute

Jin-Hong Robert Chang, PhD Inhibition of VEGF receptor dimerization and signaling in corneal lymphangiogenesis National Eye Institute

Ali Djalilian, MD Clinical Translation of Mesenchymal Stem Cell Therapy for Corneal and Ocular Surface Injuries

Department of Defense

Xiaoyi Raymond Gao, PhD Mexican American Glaucoma Genetic Study National Eye Institute

Michael Grassi, MD Diabetes Complications Pilot and Feasibility Study: Regulators that Mediate the Cellular Response to Chronic Hyperglycemia

National Institute of Diabetes and Digestive and Kidney Diseases *

Michael Grassi, MD Genomic and Genetic Studies of Diabetic Retinopathy National Eye Institute

Sandeep Jain, MD Molecular and cellular aspects of corneal nerve regeneration National Eye Institute

Sandeep Jain, MD Keratocyte Role in Guidance of Corneal Nerves National Eye Institute

Charlotte Joslin, OD, PhD Local Food Environments and Disparities in Ovarian Cancer Survival National Institute on Minority Health and Health Disparities

Iris Kassem, MD, PhD Fibrosis and Inflammation After Anterior Segment Surgery National Eye Institute

J. Jason McAnany, PhD Mechanisms Limiting Visual Performance in Retinal Degenerations National Eye Institute

Heather Moss, MD, PhD Physiologically Based Markers of Idiopathic Intracranial Hypertension National Eye Institute

David Pepperberg, PhD Nanoparticle-based Photo-activator of Voltage-gated Sodium Channels National Eye Institute

Mark Rosenblatt, MD, PhD, MBA Mechanisms of Corneal Nerve Repair National Eye Institute

Mark Rosenblatt, MD, PhD, MBA Molecular and Functional Characterization of the Regenerative Potential of Slow Cycling Corneal Epithelial Cells

National Eye Institute

Mark Rosenblatt, MD, PhD, MBA Corneal Tissue Engineering National Eye Institute*

Mahnaz Shahidi, PhD Ocular Biomarkers of Microvascular, Neural and Metabolic Function in Diabetes National Institute of Diabetes and Digestive and Kidney Diseases

Mahnaz Shahidi, PhD Noninvasive Imaging Of Chorioretinal Oxygen Tension National Eye Institute

Mahnaz Shahidi, PhD P30 Core grant for Vision Research National Eye Institute

Mahnaz Shahidi, PhD Investigating Optical and Neural Causes of Vision Loss Department of Veterans Affairs

Deepak Shukla, PhD Novel Peptides Against Modified Heparan Sulfate National Institute of Allergy and Infectious Diseases

Deepak Shukla, PhD Micro-nano platforms for HSV vaccine National Institute of Allergy and Infectious Diseases

Deepak Shukla, PhD Significance of Heparan Sulfate in HSV-1 Spread National Institute of Allergy and Infectious Diseases

Deepak Shukla, PhD and Beatrice Yue, PhD

Role of Optineurin in Ocular Herpes Infection National Eye Institute

Elmer Tu, MD Planning Grant for Parasitic Ulcer Treatment Trial Consortium National Eye Institute*

Thasarat Vajaranant, MD Optic Nerve Aging and Glaucoma National Eye Institute

Beatrice Yue, PhD Cellular Processing of Optineurin The Product of a Glaucoma Gene National Eye Institute

Xincheng Yao, PhD Functional Imaging of Retinal Photoreceptors National Eye Institute

Xincheng Yao, PhD Super-Resolution Ophthalmoscopy for In Vivo Retinal Imaging National Eye Institute

SPONSORED RESEARCH July 1, 2013 – June 30, 2015

OneVision | 33

FOUNDATION SPONSORED RESEARCH

INVESTIGATOR PROJECT TITLE FUNDING SOURCE

Vinay Aakalu, MD, MPH Study of Accessory Lacrimal Gland and Precursor Cell Biology Fight for Sight

Vinay Aakalu, MD, MPH Development of an in vitro Model of Lacrimal Cells using Stem Cells Midwest Eye-Banks

Vinay Aakalu, MD, MPH Accessory Lacrimal Tissue Precursor Cell Biology Illinois Society for the Prevention of Blindness

Vinay Aakalu, MD, MPH Lacrimal Stem Cells and Dry Eye Research American Society of Cataract and Refractive Surgery

Pablo Barrionuevo, PhD (Cao) Melanopsin Photoresponse Defi cit in Glaucoma Illinois Society for the Prevention of Blindness

Joseph Bogaard (Grassi) CYP2C9 Mediated Neuroprotection in Retinal Degenerative Disease Illinois Society for the Prevention of Blindness

Dingcai Cao, PhD Mesopic Visual Function Assessment and Risk Genotypes for Age-related Macular Degeneration

Midwest Eye-Banks

Dingcai Cao, PhD Alcohol Effects on Visual Processing in At-Risk Social Drinkers ABMRF/The Foundation for Alcohol Research

Dingcai Cao, PhD Postdoctoral Fellowship International Brain Research Organization

Ali Djalilian, MD Clinical Translation of Mesenchymal Stem Cell Trophic Factors for the Corneal Disease in Aniridia

Vision For Tomorrow

Andrew Francis, MD (Shahidi) Abnormalities in Retinal Layer Thickness due to Diabetes Assessed with Spectral Domain Optical Coherence Tomography

Illinois Society for the Prevention of Blindness

Xiaoyi Raymond Gao, PhD Fine Mapping of Genetic Loci for Central Corneal Thickness Midwest Eye-Banks

Michael Grassi, MD Cellular Studies of Apoptosis in RP Using Small Molecule Screening and RNA Interference

Foundation Fighting Blindness

Joshua Hou, MD (Cortina) Comparison of Ocular Surface Flora in Boston Keratoprosthesis Patients on Prophylactic Vancomycin vs. Linezolid

American Society of Cataract and Refractive Surgery

Joshua Hou, MD (Cortina) Characterization of Melt-associated Retroprosthetic Membranes in Patients with the Boston Keratoprosthesis using Immunohistochemistry and In-situ Hybridization


Sandeep Jain, MD Physician-Scientist Award Research to Prevent Blindness, Inc.

Sandeep Jain, MD Safety and Effi cacy of DNase I Eye Drops in Dry Eye Disease Midwest Eye-Banks

Sachin Jain, MD (Vajaranant) Functional Measures as Surrogates for Vision-related Quality of Life in Patients with Glaucoma


Charlotte Joslin, OD, PhD Racial Disparities in Ovarian Cancer Survival American Cancer Society

Iris Kassem, MD, PhD Fibrin Membrane Formation and Infl ammation After Pediatric Ocular Surgery Knights Templar Eye Foundation

Behard Milani, MD (Djalilian) The Use of Rapamycin as an Additive to Corneal Storage Media Eye Bank Association of America

Heather Moss, MD, PhD Ganglion Cell Function in Papilledema Illinois Society for the Prevention of Blindness

Paul Park (Shukla) Medical Student Fellowship: Comparative Analysis of Prophylactic and Therapeutic Effi cacies of Anti-Heparan Sulfate Peptides in Previously HSV-1 Infected Corneal Cells

Fight for Sight

Rajni Parthasarathy (Pepperberg)

Detection and Quantifi cation of Amyloid-Beta Protein in Eye Tissues Illinois Society for the Prevention of Blindness

David Pepperberg, PhD Exogenous Peptidase for Amylod-beta Degradation BrightFocus Foundation

David Pepperberg, PhD Nanoprosthesis for Retinal Ganglion Cell Photo-activation Beckman Initiative for Macular Research

Mark Rosenblatt, MD, PhD, MBA Research to Prevent Blindness, Inc. Unrestricted Departmental Grant Research to Prevent Blindness, Inc.

Joy Sarkar, PhD (Jain) Extracellular DNA in Tear Fluid: Innate Mechanism of Ocular Surface Infl ammation Illinois Society for the Prevention of Blindness

Mahnaz Shahidi, PhD Senior Scientifi c Investigator Award Research to Prevent Blindness, Inc.

Deepak Shukla, PhD Developing a NSV-2 Vaginal Microbicide that also serves as a Vaccine Center for Clinical and Translational Science

Sapna Tibrewal, MD (Jain) Role of Neutrophils in Pathogenesis of Chronic Ocular Graft-versus-Host Disease Illinois Society for the Prevention of Blindness

Elmer Tu, MD Microbial Clearance Time for Acanthamoeba Keratitis Research to Prevent Blindness, Inc.*

Thasarat Vajaranant, MD A Feasibility Study to Assess the Accuracy of Self-Reported Glaucoma Outcomes and Participant Interest in Ancillary Glaucoma Studies as Part of the Women’s Health Initiative (WHI) Extension

American Glaucoma Society

Gautam Vangipuram (Moss) Association Between Retinal Vessel Size and Short Term Intracranial Pressure Changes in Idiopathic Intracranial Hypertension


Hongyu Ying, PhD Suppression of Ocular Fibrosis by SiRNA-Nanoparticle Technology Illinois Society for the Prevention of Blindness

Beatrice Yue, PhD Fibril/Oligomer Formation by Optineurin in Vitro BrightFocus Foundation

Jimmy Zhu (R. Chang) Differential Vascular Formation in Corneal Transplant Rejection Illinois Society for the Prevention of Blindness

*Subcontracts

34

CLINICAL INVESTIGATIONS AND TRIALS

CORNEA

Soledad Cortina, MD Study of Infectious Agents in Keratoprosthesis Implanted Eyes, their Biofilm Forming Capabilities and Infectious Complications

Jose de la Cruz, MD A Multi-Center, Randomized, Placebo-Controlled Evaluation of the Safety and Efficacy of the KXL System with VibeX (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in Eyes with Keratoconus (KXL-005)

Sandep Jain, MD A Phase I/II Open-Label, Single-Center, Tolerability and Preliminary Efficacy Study Of Recombinant Human Deoxyribonuclease (Rhdnase) Eye Drops In Patients With Dry Eye Disease

Sandep Jain, MD Symptom Analysis of Dry Eye Disease

Sandep Jain, MD Polymorphism in Dry Eye and Depression

Sandep Jain, MD Presence of Neutrophil Extracellular Traps (NETS) in Dry Eye Disease

Sandep Jain, MD A Phase I/II Randomized Placebo-Controlled, Double-Blind, Single-Center, Tolerability and Preliminary Efficacy Clinical Trial of Recombinant Human Deoxyribonuclease (Rhdnase) Eye Drops in Patients with Ocular Graft-Vs-Host Disease

Sandep Jain, MD A Prospective Study to Identify Bio-Markers that Predict Onset and Progression of Ocular Graft-Vs-Host Disease in Patients who Receive Allogeneic Hematopoietic Stem Cell Transplant

Elmer Tu, MD Corneal Preservation Time Study

Elmer Tu, MD Microbiological Clearance Time For Acanthamoeba Keratitis

GLAUCOMA

Ahmad Aref, MD Omega-3 Fatty Acid Nutritional Supplementation in the Treatment of Ocular Surface Disease Associated with Intraocular Pressure-Lowering Medications

Ahmad Aref, MD Outcomes of Glaucoma Drainage Implant Surgery

Ahmad Aref, MD Outcomes of Goniotomy Surgery

Thasarat Vajaranant, MD A Feasibility Study to Assess the Accuracy of Self-Reported Glaucoma Outcomes and Participant Interest in Participating in Ancillary Glaucoma Studies in Women’s Health Initiative

Thasarat Vajaranant, MD Surgical Menopause and Risk for Premature Aging of the Optic Nerve and Glaucoma

Thasarat Vajaranant, MD Structural Assessment in Glaucoma

Thasarat Vajaranant, MD The Efficacy and Safety of Bimatoprost SR in Patients with Open-Angle Glaucoma or Ocular Hypertension

Thasarat Vajaranant, MDA Randomized, Multicenter, Double-Masked, Parallel-Group Study Comparing the Safety and Efficacy of BOL-303259-X 0.024% (Latanoprostene Bunod) Ophthalmic Solution with Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Open-Angle Glaucoma or Ocular Hypertension - APOLLO Study

Thasarat Vajaranant, MD A Double-Masked, Randomized, Multi-Center, Active-Controlled, Parallel, 3-Month Study Assessing the Safety and Ocular Hypotensive Efficacy of AR-13324 Ophthalmic Solution, 0.02% Compared to Timolol Maleate Ophthalmic Solution, 0.5% in Patients with Elevated Intraocular Pressure

Jacob Wilensky, MD Determining the Intraocular Presence of Benzylkonium Chloride

NEURO-OPHTHALMOLOGY

Heather Moss, MD, PhD P. MacIntosh Phase 2/3/ Research Study for the Treatment of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

Heather Moss, MD, PhD; J. McAnany; M. Shahidi Physiologically Based Markers of Idiopathic Intracranial Hypertension

Blue Font indicates Sponsored Filled rows indicates Enrolling Patients

OneVision | 35

OCULOPLASTIC SURGERY

Vinay Aakalu, MD, MPH Study of Accessory Lacrimal Gland Biology

RETINA

Jennifer Lim, MD; F. Chau Ocriplasmin Research to Better Inform Treatment (ORBIT)

Jennifer Lim, MD; F. Chau A Phase 2, Randomized, Double-Masked, Placebo-Controlled, Parallel Group, Multicenter Study to Compare the Effi cacy and Safety of a Chemokine CCR2/5 Receptor Antagonist (PF-04634817) with that of Ranibizumab in Adult Subjects with Diabetic Macular Edema (Pfi zer DME)

Jennifer Lim, MD; F. ChauStudy of Comparative Treatments for Retinal Vein Occlusion 2: A Multicenter, Prospective, Randomized Non-Inferiority Trial of Eyes with Macular Edema Secondary to Central Retinal Vein Occlusion, Comparing Intravitreal Bevacizumab every 4 Weeks with Intravitreal Afl ibercept every 4 Weeks (SCORE2)

Jennifer Lim, MD; F. Chau; W. Mieler Argus II Retinal Prosthesis System - Post-Approval Study (PAS)

Jennifer Lim, MD; F. Chau; W. Mieler Argus II Retinal Prosthesis System - Humanitarian Use Device (HUD)

Jennifer Lim, MD; F. Chau A Double-Masked, Randomized, Active-Controlled Study of the Effi cacy, Safety, and Tolerability of Intravitreal Administration of VEGF Trap-Eye (Intravitreal Afl ibercept Injection [IAI]) in Patients with Macular Edema Secondary to Branch Retinal Vein Occlusion

Jennifer Lim, MD; F. Chau A Phase 3, Double-Masked, Randomized Study of the Effi cacy and Safety of Intravitreal Afl ibercept to Prevent Progression to Vision-Threatening Events in Patients with Diabetic Retinopathy (Regeneron VFGTe-OD-1411)

Jennifer Lim, MD; F. Chau A Phase 2, Double-Masked, Randomized, Controlled, Multiple-Dose, Regimen-Ranging Study of the Effi cacy and Safety of Intravitreal Regn2176-3 in Patients with Neovascular Age-Related Macular Degeneration (Regeneron R2176-3-AMD-1417)

Jennifer Lim, MD; F. Chau Treatment for Central-Involved Diabetic Macular Edema in Eyes with Very Good Visual Acuity (Protocol V)

Jennifer Lim, MD; F. Chau Genes in Diabetic Retinopathy Project (Protocol Genetics)

Jennifer Lim, MD; F. Chau Peripheral Diabetic Retinopathy (DR) Lesions on Ultrawide-fi eld Fundus Images and Risk of DR Worsening Over Time (Protocol AA)

Jennifer Lim, MD; F. Chau Comparative Effectiveness Study of Afl ibercept, Bevacizumab and Ranibizumab for Diabetic Macular Edema (Protocol T)

Jennifer Lim, MD; F. Chau Intravitreal Ranibizumab or Triamcinolone Acetonide in Combination with Laser Photocoagulation for Diabetic Macular Edema (Protocol I)

Jennifer Lim, MD; F. Chau Effect of Diabetes Education during Retinal Ophthalmology Visits on Diabetes Control (Protocol M)

Jennifer Lim, MD; F. Chau An Evaluation of Intravitreal Ranibizumab for Vitreous Hemorrhage Due to Proliferative Diabetic Retinopathy (Protocol N)

Jennifer Lim, MD; F. Chau Genetics of AMD in African Americans

Jennifer Lim, MD; F. Chau An Experimental Approach to Maculopathy

Jennifer Lim, MD; F. Chau Optical Coherence Tomographical Retinal Thickness Analysis of Sickle Cell Patients

Jennifer Lim, MD; F. Chau Spatial Temporal Imaging of Human Bulbar Conjunctival Microvascular Blood Flow in Patients with Sickle Cell Disease

Jennifer Lim, MD; F. Chau A Retrospective Case Series to Assess the Effi cacy of Anti-VEGF Therapy in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion

Jennifer Lim, MD; F. Chau Retrospective Comparison between Bevacizumab (Avastin) and Ranibizumab (Lucentis) in Diabetic Macular Edema

Jennifer Lim, MD; F. Chau Surgical Outcomes of 25-Gauge Vitrectomy for Tractional Retinal Detachment

Jennifer Lim, MD; F. Chau Foveal Structure Integrity and Visual Outcome in Diabetic Retinopathy

Jennifer Lim, MD; F. Chau Evaluation of Abicipar Pegol (AGN-150998) in Patients with Decreased Vision Due to Diabetic Macular Edema (PALM)

Jennifer Lim, MD; F. Chau Systemic Immunosuppressive Therapy for Eye Diseases Cohort Study

Jennifer Lim, MD; F. Chau Biomarkers in Proliferative Retinopathies (BPR)

Lawrence Ulanski, MD Multi-Center, Randomized, Single Masked Phase 2 Study of Intravitreal Sirolimus in the Treatment of Central Geographic Atrophy Associated with Age-Related Macular Degeneration

Lawrence Ulanski, MD Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device

Lawrence Ulanski, MD AMD Phenotype and Genotype Study (APGS)

To learn more about any of these investigations and trials, including how to refer patients, please call (312) 996-6590.

36

HONOR ROLL OF DONORS Fiscal Year 2014 (July 1, 2013 –June 30, 2014)

$100,000+ Research to Prevent Blindness Inc.

$50,000-99,999 American Health Assistance Foundation Foundation Fighting Blindness Dr. R. Mark and

Mrs. Monica J. W. Hatfield Hope for Vision Komarek-Hyde-McQueen Foundation Dr. John H. (DEC) and

Mrs. Mary K. Panton (DEC) Parent Petroleum, Inc. Edward Tuck Estate (DEC)

$5,000-49,999 ABMRF/The Foundation for Alcohol

Research American Glaucoma Society Braude Foundation Carol Lavin Bernick Family Foundation Ms. Anne C. Haffner Illinois Society for the Prevention

of Blindness Mr. Gary R. and Mrs. Susan M. Janko JVA Partners LLC Dr. David G. and

Mrs. Norene M. McLone Midwest Eye-Banks and

Transplantation Center Dr. Allen and Mrs. Lynett Putterman James E. Rathmann Estate (DEC) Regenron Pharmaceuticals Edwin F. Schild Foundation Arch W. Shaw Foundation Dr. Don M. Smart

$1,000-4,999 Dr. Afzal and Dr. Shireen Ahmad Dr. Alan J. and Mrs. Jennifer K. Axelrod Mr. Albert Barsky Dr. Brian Bernard Berger Mr. Julian L. and Mrs. Joan S. Berman Dr. Norman P. and Joy E. Blair Mr. Barry J. and Mrs. Barbara P. Carroll Dr. Richard M. Chavis The Chicago Community Foundation Chicagoland Retinal Consultants LLC Mrs. Anamika Das and

Dr. Harit K. Bhatt Dr. Anthony G. and Mrs. M. Ann Finder Mr. Kevin R. and Mrs. Lori R. Fornoff Dr. David J. Fuerst Mrs. Anita S. Gerber and Dr. Joel Sugar Dr. Morton F. and Mrs. Myrna Goldberg Hackberry Endowment Partners

c/o The Malkin Families Mrs. Diane K. Henry KLS Martin, LP

Dr. Paul A. Knepper and Dr. Zibute Zaparackas

Dr. David M. Lubeck Dr. Harris (DEC) and

Mrs. Jeanne Ripps Dr. William L. Schey Dr. Veeral S. and

Dr. Monica Johal Sheth Ms. Dorothy T. Tannenbaum Dr. Howard H. and Mrs. Tena Tessler Dr. George J. and

Dr. Patricia Polin Wyhinny

$100-999 Mr. Shankarnaray Adapathya Dr. Muayyad Alubaidi and

Dr. Muna I. Naash Dr. Phillip D. Alward Bailey & Wakil Eye Physicians &

Surgeons PLLC Mr. Charles L. Barsky Mr. Chad J. and Mrs. Marsha Beste Dr. Abdhish R. Bhavsar Dr. Brian S. and Mrs. Dina M. Biesman Dr. John Paul Broderson Mrs. Marie J. Bugajski Dr. Samuel J. Cascio Dr. Lawrence I. Chapman Dr. Felix Y. Chau Chicago Cornea Consultants, Ltd. Dr. David M. and

Mrs. Barbara L. Cohen Dr. Mary Davidson Discover Financial Services Dr. Randy J. Epstein Mr. Dan and Mrs. Linda Fowler Dr. Joseph B. and Mrs. Leslie Garber Dr. Carl Garfinkle Miss Elden Genitis Dr. Marc F. Greenberg and

Ms. Susan H. Glatt Dr. Frank R. Guastella Dr. Nancy A. Hamming Mr. Richard A. and

Mrs. Mary E. Howell Dr. Donald S. Jacobs Dr. Ronald A. Kalayta Dr. Stuart J. Kaufman Dr. Jeremy D. Keenan The Kestnbaum Foundation Dr. Daniel F. Kiernan Dr. Timothy A. Kisla Kraz Construction Dr. Eligijus P. and Mrs. Ale B. Lelis Dr. Michael A. Lemp Mr. Bernard Leviton Dr. Singyour Li and Mr. Eugene Wang Mrs. Patricia M. Livingston Mr. David S. and

Mrs. Glennda G. Lockard Ms. Barbara Anne Macek Dr. Paul A. Mahlberg Dr. David I. Malitz

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Mrs. Katherine Mendelblatt Midwestern Association of Plastic

Surgeons Mr. Arnold D. Miller Dr. Marilyn T. Miller Dr. David D. Morimoto Dr. Marcus and Mrs. Suhair Muallem National Philanthropic Trust Mrs. Barbara P. Newman Dr. T. Michael Nork Dr. Michael A. Nyberg Mr. Anthony J. Onesto Ms. Lynn Orschel Dr. Robert W. and Mrs. Marika Panton Dr. Ashok R. Penmatcha Mr. William D. Perkins Mr. Sheldon and Ms. Marcia Pevsner Mr. Michael S. and Mrs. Sally L. Pope Mr. Joel F. Raven Ms. Norma B. Raven Mr. James T. and Mrs. Karen Reid Dr. Kenneth I. and

Dr. Raiselle C. Resnick Dr. David S. Robbin Mr. Larry R. and Mrs. Diane M. Rogers Dr. Ari and

Mrs. Kimberly Miller Rubenfeld Mrs. Darleen Salomon Dr. Miriam T. Schteingart Light Mr. Ira J. and

Mrs. Beverly W. Schulman Mr. Leonard H. Solomon Dr. Sriram Sonty Dr. Alan V. Spigelman Dr. Karen D. Sumers and

Mr. Jeffry Finkel Dr. John B. Thompson Mr. Robert B. and Mrs. Sheri B. Tisdahl Dr. Samuel J. Vainisi Dr. Thasarat S. Vajaranant Ms. Patricia S. Wager Dr. Aida S. Wakil Mrs. Marilyn K. Ward Wells Fargo Foundation Dr. Robert D. Wertz Mr. Moshe K. Wilensky Dr. Martha J. Willi Willow Springs Lioness Club Mr. Tony Zamora

Fiscal Year 2015 (July 1, 2014 –June 30, 2015)

$100,000+ American Health Assistance Foundation Cless Family FoundationDr. Steven A. and

Mrs. Paticia Ann Cullinan Research to Prevent Blindness Inc. The Vision For Tomorrow Foundation

$50,000-99,999 Ms. Bonnie Crossley Ms. Suellen Haywood Melvin and Bren Simon Charitable

Foundation Dr. John H. (DEC) and

Mrs. Mary K. Panton (DEC) Mr. David Young

$5,000-49,999 Alcon Laboratories, Inc. Allergan USA, Inc. American Society Of Cataract &

Refractive Surgery Arch W. Shaw Foundation Atlanta Eye Consultants, PC Dr. Norman P. and Mrs. Joy E. Blair BP Products North America, Inc. Braude Foundation Chicagoland Retinal Consultants LLC Mr. William H. and Mrs. Tammy Crown Edwin F. Schild Foundation Fight for Sight, Inc. Genentech USA Ms. Anne C. Haffner Dr. R. Mark and

Mrs. Monica J. W. Hatfield Illinois Society for the Prevention of

Blindness Dr. Sao Cheng Liu Dr. Sao Jang and Mrs. Thuy Ti Bick Liu Omega Surgery Centers, LLC Parent Petroleum, Inc. Dr. Allen and Mrs. Lynett Putterman Mrs. Ann S. Rasch Regenron Pharmaceuticals Mr. John H. Simpson Dr. Don M. Smart Mrs. Jean Tsai and

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$1,000-4,999 All Temperature Systems, Inc Dr. Phillip D. Alward Dr. Ahmad A. Aref and

Mrs. Noha El-Sharkawy Auto MD, LLC Ms. Alice Anthony Dr. Alan J. and Mrs. Jennifer K. Axelrod BMO Harris Bank NA Mr. Albert Barsky Mr. Julian L. and Mrs. Joan S. Berman

OneVision | 37

BMC, Inc. Dr. Mark S. Brown Burke Transport Service, Inc. Dr. Michael Burnstine Mr. Richard P. and

Mrs. Jane J. Campbell Mr. Barry J. and Mrs. Barbara P. Carroll Dr. Richard P. Carroll Dr. Samuel J. Cascio Dr. Felix Y. Chau The Chicago Community Foundation Crosstown Electric, Inc. Mr. Daniel A. and Mrs. Dana Dumezich Dr. Deepak P. and

Mrs. Catherine Edward Equilon Enterprises LLC Exxon Mobil Dr. Kenneth A. Feldman Mr. Kevin R. and Mrs. Lori R. Fornoff Dr. David J. Fuerst Mrs. Anita S. Gerber and Dr. Joel Sugar Ms. Virginia H. Hans Dr. John B. Holds and

Dr. Sophia Chung Mr. David Huizenga Dr. Daniel F. Kiernan Kenan Advantage Group, Inc. Dr. Paul A. Knepper and

Dr. Zibute Zaparackas Mr. David S. and

Mrs. Glennda G. Lockard Lynch Team M. Raess & Son Trucking, LLC Macula Foundation Inc. Mr. Nevo L. (DEC) and

Mrs. Laura J. Martelli Medical Eye Services, Ltd. Metro Environmental Contractors Inc Midwest Maintenance Systems, Inc. Mobile Telecommunications Ltd. Parvin Clauss Sign Company Patriot Capital Corporation Pepsi Beverage Company Mr. Michael and Mrs. Sandra Perlow The Philip and Myn Rootberg

Foundation Purpora Engineering, Inc. Mr. Andrew P. and Mrs. Susan L. Rasch Mr. James T. and Mrs. Karen Reid Robert B. Scott Ocularists, Ltd. Mr. David W. Ruttenberg Dr. William L. Schey Mr. Ira J. and

Mrs. Beverly W. Schulman Dr. Veeral S. and

Dr. Monica Johal Sheth Source North America Ms. Nancy A. Spina Ms. Dorothy T. Tannenbaum Dr. Howard H. and Mrs. Tena Tessler Warren Retina Associates, PA Mrs. Beverly J. Yusim

$100-999 Mr. Shankarnaray Adapathya Dr. William M. and Mrs. Ellen G. Adler Mr. Frank Baade Badger Land Mr. Thomas W. Balogh Bausch & Lomb Ms. Kimberly Behl Dr. Abdhish R. Bhavsar Big Red Rooster Flow, LLC Dr. Fred S. and Mrs. Cynthia K. Bodker Brookmeade Healthcare Mrs. Bonnie P. Byer Dr. Richard T. and

Mrs. Annette C. Caleel Mr. Irvin and Mrs. Sharon Caplan Mr. F. Robert and Mrs. Vicki Carbine Ms. Susan Carlins Mr. Dennis M. Carr Dr. Lawrence I. Chapman Cedars of Lebanon Foundation, Inc. Mr. John and Mrs. Sylvia Chlopek Mr. Dennis and Mrs. Marla Chorney Ms. Valerie A. Chrysokos Mr. Ronald P. and

Mrs. Kathryn H. Chucan Mr. Stephen and Mrs. Anne Cless Mr. Donald K. and Mrs. Francis Coe Dr. David M. and

Mrs. Barbara L. Cohen Mrs. Donna J. Combs Mr. Patrick H. Combs Creative Retail Solutions Dr. Albert Cytryn Dr. Mary Davidson Mr. Irvin and Mrs. Christine DeAtley DeMarco Sciaccotta Wilkens &

Dunleavy, LLP Mrs. Maureen De Matoff Downers Grove Cellular Mrs. Audrey V. Eisenmann and

Dr. David R. Pepperberg Dr. Gil Epstein Mr. Sidney and

Mrs. Sondra Berman Epstein Dr. Anthony G. and Mrs. M. Ann Finder Mr. Dan Fowler Dr. Joseph B. and Mrs. Leslie Garber Miss Elden Genitis Mr. Isak V. and Mrs. Nancy H. Gerson Mr. Gerald P. and Mrs. Dale E. Ginsburg Dr. David A. and Dr. Dee Anna Glaser Mr. David Gohlund Goldman Philanthropic Partnerships Dr. Juliet S. Goldsher Mr. Nick Gouskos Mr. Ronald and Mrs. Marilynn Grais Graphics Factory, Inc. Dr. Marc F. Greenberg and

Ms. Susan H. Glatt Ms. Rita M. Guenther Mr. William D. and Mrs. Sandi Gurowitz

Ms. Lee R. Hamilton Mr. Denis C. Harrington Mr. Mark D. and

Mrs. Deborah L. Hellman Mrs. Diane K. Henry Hodges Westside Truck Center, Inc. Mr. Michael E. Hoff Huntley Cellular Ltd. Dr. Donald S. Jacobs Mr. Nicholas C. Jannotta Mr. Larry M. Jordan Ms. Betty C. Kalina Mr. Dale A. and

Mrs. Patricia A. Karlovsky Ms. Patricia J. Karlowski Dr. Jeremy D. Keenan Mr. Paul and Mrs. Barbara Koch Mr. Paul Kraszyk Mr. Mark A. Kroupa Mr. Irwin B. and

Ms. Linda Y. Landsberg Mr. Kyuyeon Han and Ms. Hyun Lee Dr. Eligijus P. and Mrs. Ale B. Lelis Dr. Mark R. Levine Mrs. Patricia M. Livingston Lowery Asset Consulting, LLC Paul A. Mahlberg Ms. Alberta K. Maljan Dr. Ira Martin and Mrs. Renee Grais Dr. John J. McGetrick Dr. Michael E. Migliori Mr. Kevin D. and

Mrs. Denise Santor-Mitzit Dr. Dorothy M. Moore Mr. Gerald M. and

Mrs. Debra M. Moriarty Dr. David D. Morimoto Naperville Cellular Ltd. Mrs. Barbara P. Newman Mr. Dennis S. Niemczura Dr. T. Michael Nork N&J Gas and Food Mart Inc. Mr. William R. and

Mrs. Denise P. O’Connell Mr. Kevin J. O’Donnell Mr. Anthony J. Onesto Ms. Jenny Ori Ms. Therese L. Paluck Dr. Robert W. and Mrs. Marika Panton Dr. Rakesh M. Patel Dr. Ashok R. and

Mrs. Sunita Penmatcha Mr. William D. and Mrs. Francis Perkins Pinnacle Oil Holdings, LLC Mrs. Sally L. Pope Mr. Jay J. and Mrs. Lorraine Popek Mr. Ron D. Putterman Mr. Joel F. Raven Ms. Norma B. Raven R. Carlson & Sons, Inc. Mrs. Badonna Reingold R J Schauer & Associates Ltd

Dr. David S. and Mrs. Diane Robbin Mr. Wallace H. Roberts Jr. and

Mrs. Susan S. Roberts Ms. Jennifer Romes Ronnoco Coffee Ms. Rosann M. Root Ms. Evelyn S. Ross Mr. Michael E. Salvati and

Ms. Charlotte Rubinstein Mr. J. E. and Mrs. Regina L. Rurode Dr. Sigmund L. Sattenspiel Ms. Carole M. Schroeder Ms. Susan A. Schroeder Dr. Miriam T. Schteingart Light Mr. Irwin J. and Mrs. Shirley Segal Dr. Mahnaz Shahidi Dr. Joanne Shen and

Dr. Robert Ortega-Hamilton Shopco U.S.A. Mr. James A. and Mrs. Jean M. Shuba Mr. William F. Sieczkowski Jr. Ms. Gayle Simmons and

Mr. Ray Ziolkowski Mr. George M. Singh Solaray, LLC Solution Systems, Inc. Dr. Shalini Sood-Mendiratta Dr. Alan V. Spigelman Dr. Bruce E. Spivey and

Mrs. Patti Birge Tyson Ms. Jeanne L.B.S. Stoker Dr. John B. and Mrs. Rita Thompson Mr. William E. Tienken Tire Country of Jacksonville, Inc. Ultimate Lighting, Inc. Dr. Samuel J. and

Mrs. Gretchen Vainisi Dr. Thasarat S. Vajaranant Ms. Evelyn G. Valentino Mr. Ross G. and

Mrs. Tamara Van Drunen VFS Concrete, Inc. Mrs. Marilyn K. Ward Weiss Construction Group, LLC Wells Fargo Foundation Dr. Robert D. Wertz Dr. Jacob T. and

Mrs. Rochelle Goldwater Wilensky Willow Springs Lioness Club Mr. Kenneth K. and Mrs. Linda E. Wolff Woodstock Cellular Ltd. Mr. Marion R. and Ms. Jeanne Yeargin Yorkville Mobility, Ltd. Mr. Gerald L. and

Mrs. Linda W. Zielinski

38

Residents

THIRD YEAR (Class of 2016) FIRST YEAR (Class of 2018)SECOND YEAR (Class of 2017)

OPHTHALMOLOGISTS IN TRAINING

Judy Chen, MD | CO-CHIEF RESIDENT MD—University of Chicago

Julie Goldman, MD MD—Columbia University

Mohsin Ali, MD MD—Jefferson Medical College

Eric Feinstein, MD MD—University of Virginia

Shilpa Gulati, MD MD—University of Michigan

Susie Chen, MD MD—University of Wisconsin

Andrew Francis, MD MD—Boston University

Robert Hyde, MD, PhD MD/PhD—Case Western Reserve University

Mark Dikopf, MD MD—University of Illinois, Chicago

Abed Namavari, MD MD—Tehran University

Alexander Pleet, MD MD—University of Pennsylvania

Siya Huo, MD MD—Cleveland Clinic Lerner College of Medicine

Ketki Soin, MD | CO-CHIEF RESIDENTMD—Jefferson Medical College

Bailey Shen, MD MD—Case Western Reserve University

Kai Kang, MD MD—Weill Cornell Medical College

Merina Thomas, MD MD—Vanderbilt University

Dan Yoon, MD MD—New York University

Mei Zhou, MDMD—University of Chicago

OneVision | 39

Clinical Fellows

CORNEA Claire Kelliher, MDMD—Trinity College DublinResidency—Scheie Eye Institute

CORNEA Peter Wu, MDMD—Texas Tech UniversityResidency—University of California, Davis

GLAUCOMASachin Jain, MDMD—University of Illinois, PeoriaResidency—Illinois Eye and Ear Infi rmary

NEURO-OPHTHALMOLOGY Milena Stosic, MDMD—University of BelgradeResidency in Neurology—Baylor College of Medicine

OCULOPLASTIC SURGERYScott Jones, MDMD—University of LouisvilleResidency—Tulane University

PEDIATRIC OPHTHALMOLOGY Majid Rouhbakhshzaeri, MDMD and Residency—Mashhad University of Medical Sciences

RETINARandee Miller, MDMD—Wayne State UniversityResidency—Illinois Eye and Ear Infi rmary

CLASS OF 2015 RESIDENTS (left to right) Drs. Bryan Kim, Kaitlyn Wallace Nolan, Michael Andreoli, Sachin Jain and Asim Farooq

RETINAMichael Andreoli, MDMD—Boston UniversityResidency—Illinois Eye and Ear Infi rmary

RETINAPeter Chang, MDMD—Tufts UniversityResidency—The New York Eye and Ear Infi rmary

CLASS OF 2014 RESIDENTS Front row: Drs. Kavitha Sivaraman, Randee Miller, Kevin Patel. Back row: Drs. Janet Lim, Senad Osmanovic, Adam Prickett

40

Aakalu VK, Patel RM, Lim J, Setabutr P. Orbital histiocytic sarcoma in a 2-year-old child. Ophthal Plast Reconstr Surg. 2014 Nov-Dec;30(6):e143-5.

Abbasian J, Blair N, Shahidi M, Kaufman L, Blair M, et al. Macular optical coherence tomography in patients with uni-lateral optic nerve hypoplasia. J AAPOS. 2015 Feb;19(1):57-61.

Afsharkhamseh N, Movahedan A, Djalilian AR, et al. Cataract surgery in patients with ocular surface disease: An update in clinical diagnosis and treatment. Saudi J Ophthalmol. 2014 Jul;28(3):164-7.

Agrawal H, Aref AA, Traish A, et al. A neonate with bilateral corneal opacities and glaucoma. Pediat Ann.2014 Feb;43(2):60-3.

Andreoli MT, Aakalu V, Setab-utr P. Epidemiological trends in malignant lacrimal gland tumors. Otolaryngol Head Neck Surg. 2015 Feb;152(2):279-83.

Andreoli MT, Lim JI. Cot-ton-wool spots and retinal hem-orrhages. Interferon-associated retinopathy. JAMA Ophthalmol. 2014 Apr 1;132(4):503-4.

Andreoli MT, Lim JI. Optical coherence tomography retinal thickness and volume measure-ments in X-linked retinoschi-sis. Am J Ophthalmol. 2014 Sep;158(3):567-73.

Andreoli MT, Yiu G, Hart L, et al. B-scan ultrasonography following open globe repair. Eye (Lond). 2014 Apr;28(4):381-5.

Antoine TE, Jones KS, Shukla D, et al. Zebrafish: modeling for herpes simplex virus infections. Zebrafish. 2014 Feb;11(1):17-25.

Antoine TE, Shukla D. Inhibition of myosin light chain kinase can be targeted for the development of new therapies against herpes simplex virus type-1 infection. Antivir Ther. 2014;19(1):15-29.

Antoine TE, Yakoub A, Shukla D, et al. Zebrafish 3-O-sulfo-transferase-4 generated heparan sulfate mediates HSV-1 entry and spread. PLoS One. 2014 Feb 3;9(2):e87302.

Aref AA, Sayyad FE, Ayres B, et al. Acute bilateral angle

closure glaucoma induced by methazolamide. Clin Ophthalmol. 2013;7:279-82.

Aref AA, Sayyad FE, Mwanza JC, et al. Diagnostic specifici-ties of retinal nerve fiber layer, optic nerve head, and macular ganglion cell-inner plexiform layer measurements in myopic eyes. J Glaucoma. 2014 Oct-Nov;23(8):487-93.

Aref AA, Scott IU. Twenty-four-hour intraocular pressure monitoring: it’s about time. JAMA Ophthalmol. 2013 Nov;131(11):1403-4.

Aref AA, Sivaraman KR, Djalilian AR. Glaucoma Drainage Implant Surgery and Ocular Surface Transplant Graft Preser-vation. Semin Ophthalmol. 2015 May;30(3):210-3.

Aref AA. Generic drugs for the treatment of ocular conditions: changing the treatment land-scape. Expert Rev Clin Pharma-col. 2014 Sep;7(5):551-3.

Asvat Y, Cao D, Africk JJ, et al. Feasibility and effectiveness of a community-based smok-ing cessation intervention in a racially diverse, urban smoker cohort. Am J Public Health. 2014 Sep;104 Suppl 4:S620-7.

Avery RL, Bakri SJ, Mieler WF, et al. Intravitreal injection tech-nique and monitoring: updated guidelines of an expert panel. Retina. 2014 Dec;34 Suppl 12:S1-S18.

Baldwin J, Shukla D, Tiwari V, et al. A role for 3-O sulfated heparan sulfate in promoting human cytomegalovirus infection in human iris cell. J Virol. 2015 May 1;89(9):5185-92.

Baradaran-Rafii A, Shirzadeh E, Eslani M, et al. Optical cor-rection of aphakia in children. J Ophthalmic Vis Res. 2014 Jan;9(1):71-82.

Barmettler A, Nissanka N, Rosenblatt MI, et al. Magnetic systems for tarsorrhaphy. Oph-thal Plast Reconstr Surg. 2014 Jul-Aug;30(4):305-8.

Barrionuevo PA, Cao D. Con-tributions of rhodopsin, cone opsins, and melanopsin to post-receptoral pathways inferred

from natural image statistics. J Opt Soc Am A Opt Image Sci Vis. 2014 Apr 1;31(4):A131-9.

Barrionuevo PA, McAnany JJ, Cao D, et al. Assessing rod, cone, and melanopsin contribu-tions to human pupil flicker re-sponses. Invest Ophthalmol Vis Sci. 2014 Feb 4;55(2):719-27.

Beleggia F, Li Y, Maumenee IH, et al., CRIM1 haploinsufficiency causes defects in eye devel-opment in human and mouse. Hum Mol Genet. 2015 Apr 15;24(8):2267-73.

Bhat PV, Goldstein DA. Dexa-methasone Intravitreal Implant (Allergan) for the Treatment of Noninfectious Uveitis. Expert Opinion on Orphan Drugs. 2014 Mar; 2(3): 301-10.

Bhat PV, Goldstein DA. Review of the Latest Local Treatments for Uveitis. Expert Review of Ophthalmology. 2014 Oct.;9(5): 401-12.

Bourne RR, Vision Loss Expert Group of the Global Burden of Disease Study [Lim JI, Joslin CE], et al., Prevalence and caus-es of vision loss in high-income countries and in Eastern and Central Europe: 1990-2010. Br J Ophthalmol. 2014.

Boyer DS, V.I.S.I.O.N. Study Group [Lim JI, Mieler WF], et al. Effect of pegaptanib sodium 0.3 mg intravitreal injections (Macugen) in intraocular pressure: posthoc analysis from V.I.S.I.O.N. study. Br J Ophthal-mol. 2014 Nov;98(11):1543-6.

Boyer DS, Ozurdex MEAD Study Group [Ulanski LJ], et al. Three-year, randomized, sham-controlled trial of dexa-methasone intravitreal implant in patients with diabetic macular edema. Ophthalmology. 2014 Oct;121(10):1904-14.

Bressler SB, Diabetic Retinop-athy Clinical Research Network [Blair M, Lim JI], et al. Explorato-ry analysis of the effect of intra-vitreal ranibizumab or triamcin-olone on worsening of diabetic retinopathy in a randomized clinical trial. JAMA Ophthalmol. 2013 Aug;131(8):1033-40.

Bressler SB, ; Diabetic Retinop-athy Clinical Research Network Investigators [Blair M, Lim JI],

et al. Repeated intravitreous ranibizumab injections for diabetic macular edema and the risk of sustained elevation of intraocular pressure or the need for ocular hypotensive treat-ment. JAMA Ophthalmol. 2015 May;133(5):589-97.

Bui KM, Chow CC, Mieler WF. Treatment of recalcitrant radia-tion maculopathy using intravit-real dexamethasone (Ozurdex) implant. Retin Cases Brief Rep. 2014 Summer;8(3):167-70.

Bui KM, Farooq AV, Moss HE, Lin AY, et al. Parenchymal anaplastic astrocytoma present-ing with visual symptoms due to bilateral optic nerve sheath involvement. J Neuroophthalmol. 2013 Sep;33(3):313-6.

Bui KM, Garcia-Gonzalez JM, Patel SS, Lin AY, Goldstein DA, et al. Directed conjunctival biopsy and impact of histologic sectioning methodology on the diagnosis of ocular sarcoidosis. J Ophthalmic Inflamm Infect. 2014 Mar 18;4(1):8.

Bussel II, Aref AA. Dietary factors and the risk of glaucoma: a review. Ther Adv Chronic Dis. 2014 Jul;5(4):188-94.

Byun YS, Sarkar J, Jain S, et al. Keratocytes derived from spher-oid culture of corneal stromal cells resemble tissue resident keratocytes. PLoS One. 2014 Nov 10;9(11):e112781.

Cao D, Barrionuevo PA. Esti-mating photoreceptor excitations from spectral outputs of a personal light exposure mea-surement device. Chronobiol Int. 2015 Mar;32(2):270-80.

Cao D, Nicandro N, Barrionuevo PA. A five-primary photostimu-lator suitable for studying intrin-sically photosensitive retinal gan-glion cell functions in humans. J Vis. 2015 Jan 26;15(1):15.1.27.

Cao D. S-cone discrimination in the presence of two adapting fields: data and model. J Opt Soc Am A Opt Image Sci Vis. 2014 Apr 1;31(4):A65-74.

Carvalho-de-Souza JL, Treger JS, Pepperberg DR, et al. Photosensitivity of Neurons Enabled by Cell-Targeted Gold Nanoparticles. Neuron. 2015 Apr 8;86(1):207-17.

FACULTY PUBLICATIONSIllinois Eye and Ear Infirmary

OneVision | 41

Chang Q, Cao D, Grassi MA, et al. Cytochrome P450 2C epoxy-genases mediate photochemical stress-induced death of photore-ceptors. J Biol Chem. 2014 Mar 21;289(12):8337-52.

Cheng CY, Consortium for Refractive Error and Myopia; Fuchs’ Genetics Multi-Center Study Group [Sugar J, Tu E, Djalilian AR]; Wellcome Trust Case Control Consortium 2; Dia-betes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group; et al. Nine loci for ocular axial length identifi ed through genome-wide associa-tion studies, including shared loci with refractive error. Am J Hum Genet. 2013 Aug 8;93(2):264-77.

Chew EY, Age-Related Eye Disease Study Research Group [Lim JI], et al. Long-term effects of vitamins C and E, �-carotene, and zinc on age-related macular degeneration: AREDS report no. 35. Ophthalmology. 2013 Aug;120(8):1604-11.

Chow CC, Mieler WF. Vitamin A defi ciency and xerophthalmic fundus in autoimmune hepatitis and cirrhosis. Retin Cases Brief Rep. 2014 Summer;8(3):164-6.

Ciralsky JB, Chapman KO, Rosenblatt MI, et al. Treatment of Refractory Persistent Corneal Epithelial Defects: A Standard-ized Approach Using Continuous Wear PROSE Therapy. Ocul Immunol Infl amm. 2014 Mar 21.

Collison FT, Fishman GA, McAnany JJ, et al. Psycho-physical measurement of rod and cone thresholds in stargardt disease with full-fi eld stimuli. Retina. 2014 Sep;34(9):1888-95.

Cortina MS, Hallak JA. Vision-related quality-of-life assessment using NEI VFQ-25 in patients after Boston kerato-prosthesis implantation. Cornea. 2015 Feb;34(2):160-4.

Cronemberger MF, Polati M, Miller M, et al. Prevalence of refractive errors in Möbius se-quence. Arq Bras Oftalmol. 2013

Jul-Aug;76(4):237-9.

Danis RP, AREDS2 Study Group [Ulanski LJ, Lim J, Niec M], et al. Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 Report Number 2). Invest Ophthalmol Vis Sci. 2013 Jul 8;54(7):4548-54.

Diabetic Retinopathy Clinical Re-search Network [Lim JI, Chau FY, Leiderman YI, Ulanski LJ]. Afl ibercept, Bevacizumab, or Ra-nibizumab for Diabetic Macular Edema. N Engl J Med. 2015 Mar 26;372(13):1193-203.

Dikopf MS, Chow CC, Mieler WF, Tu EY. Cataract extraction outcomes and the prevalence of zonular insuffi ciency in retinitis pigmentosa. Am J Ophthalmol. 2013 Jul;156(1):82-88.

Drapala PW, Mieler WF, Kang-Mieler JJ, et al. The effect of glutathione as chain transfer agent in PNIPAAm-based ther-mo-responsive hydrogels for con-trolled release of proteins. Pharm Res. 2014 Mar;31(3):742-53.

Elliott SL, Cao D. Scotopic hue percepts in natural scenes. J Vis. 2013 Nov 14;13(13):15.

Ennis R, Cao D, Lee BB, et al. Eye movements and the neural basis of context effects on visual sensitivity. J Neurosci. 2014 Jun 11;34(24):8119-29.

Esfahani D, Stevenson M, Moss H, et al. O-011 Quanti-tative MRA is Correlated with Intravascular Pressures Before and After Venous Sinus Stenting: Implications for Treatment and Monitoring. J Neurointerv Surg. 2014 Jul;6 Suppl 1:A6-7.

Eslani M, Baradaran-Rafi i A, Djalilian AR, et al. The ocular surface chemical burns. J Oph-thalmol. 2014;2014:196827.

Eslani M, Movahedan A, Djalilian AR, et al. The role of toll-like receptor 4 in corneal epithelial wound healing. Invest Ophthalmol Vis Sci. 2014 Sep 2;55(9):6108-15.

Farooq AV, Lim JI. Subcon-junctival hemorrhages and retinal vascular abnormalities. JAMA Ophthalmol. 2015 Feb 1;133(2):217-8.

Farooq AV, Tu EY, D’jalilian AR, Traish AS, Hou JH. Persistent staining of lattice lines after intraoperative trypan blue use in patients with lattice corneal

dystrophy. Cornea. 2014 Nov;33(11):1235-7.

Farooq AV, Patel RM, Lin AY, Setabutr P, Aakalu VK, et al.. Fungal Orbital Cellulitis: Present-ing Features, Management and Outcomes at a Referral Center. Orbit. 2015 Jun;34(3):152-9.

Farooq AV, Soin K, Moss HE. Alternating skew deviation in association with anti-glutamic acid decarboxylase antibod-ies. Neuroophthalmology. 2015;39(3):140-143. Epub 2015 May 13.

Fawzi AA, Moss HE, Lowry JL, et al. Clinicopathologic report of ocular involvement in ALS patients with C9orf72 muta-tion. Amyotroph Lateral Scler Frontotemporal Degener. 2014 Dec;15(7-8):569-80.

Feinstein E, Farooq AV, Lin AY, Traish AS. Bilateral conjunc-tival tuberculosis presenting as mass lesions. Can J Ophthalmol. 2015 Feb;50(1):e11-3.

Feinstein E, Kaliki S, Shields CL, et al. Choroidal metastasis from leiomyosarcoma in two cas-es. Oman J Ophthalmol. 2014 Jan;7(1):19-21.

Feinstein EG, Lim JI. New pigmented lesion over a site of tumor treatment. JAMA Ophthal-mol. 2015 May;133(5):601-2.

Francis AW, Gyasi ME, Adjuik M, et al. Comparison of primary open angle glaucoma patients in rural and urban Ghana. Afr Health Sci. 2014 Sep;14(3):729-35.

Francis AW, Lim JI, Chau FY. Sudden-onset paracentral vision loss. JAMA Ophthalmol. 2014 Nov;132(11):1367-8.

Fridberg DJ, Cao D, Grant JE, et al. Naltrexone improves quit rates, attenuates smoking urge, and reduces alcohol use in heavy drinking smokers attempting to quit smoking. Alcohol Clin Exp Res. 2014 Oct;38(10):2622-9.

Fuchs’ Genetics Multi-Center Study Group [Sugar J, Tu E, Djalilian AR], Wellcome Trust Case Control Consortium 2; Dia-betes Control and Complications Trial/Epidemiology of Diabetes Interventions, and Complications Research Group, et al. Nine loci for ocular axial length identifi ed through genome-wide associa-tion studies, including shared loci with refractive error. Am J Hum Genet. 2013 Aug 8;93(2):264-77.

Gao X, Gauderman WJ, Varma R, et al. Native American an-cestry is associated with severe diabetic retinopathy in Latinos. Invest Ophthalmol Vis Sci. 2014 Aug 21;55(9):6041-5.

Gao X, Xu J, Starmer J. Fastq2vcf: a concise and trans-parent pipeline for whole-exome sequencing data analyses. BMC Res Notes. 2015 Dec;8(1):1027.

Gatinel D, Azar DT, Dumas L, et al. Effect of anterior corneal surface asphericity modifi cation on fourth-order zernike spherical aberrations. J Refract Surg. 2014 Oct;30(10):708-15.

Giovingo M, Yue BY, Knepper PA, et al. sCD44 overexpression increases intraocular pressure and aqueous outfl ow resistance. Mol Vis. 2013 Nov 1;19:2151-64.

Gowrisankaran S, McAnany JJ, Alexander KR. Poststimulus response characteristics of the human cone fl icker electro-retinogram. Vis Neurosci. 2013 Jul;30(4):147-52.

Grassi MA, Rao V, Bogaard JD, et al. Genetic variation is the major determinant of individual differences in leukocyte endothe-lial adhesion. PLoS One. 2014 Feb 10;9(2):e87883.

Grassi MA, Gao X, DCCT/EDIC Research Group, et al. Validity of self-report in type 1 diabetic subjects for laser treatment of retinopathy. Ophthalmology. 2013 Dec;120(12):2580-6.

Grybauskas A, Yue BY, Knep-per PA, et al. ABCB1 transporter and Toll-like receptor 4 in tra-becular meshwork cells. Mol Vis. 2015 Mar 5;21:201-12.

Guaiquil VH, Hewing NJ, Rosenblatt MI, et al. A murine model for retinopathy of pre-maturity identifi es endothelial cell proliferation as a potential mechanism for plus disease. Invest Ophthalmol Vis Sci. 2013 Aug 7;54(8):5294-302.

Guaiquil VH, Pan Z, Rosenblatt MI, et al. VEGF-B selectively regenerates injured peripheral neurons and restores sensory and trophic functions. Proc Natl Acad Sci U S A. 2014 Dec 2;111(48):17272-7.

Guerrero EG, Marsh JC, Cao D, et al. Gender disparities in utilization and outcome of comprehensive substance abuse treatment among racial/ethnic groups. J Subst Abuse Treat. 2014 May-Jun;46(5):584-91.

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Guthrie MJ, Mieler WF, Kang-Mieler JJ, et al. Objective area measurement technique for choroidal neovascularization from fluorescein angiography. Mi-crovasc Res. 2014 Jan;91:1-7.

Gyasi ME, Francis AW, Adjuik M, et al. The Effect of Medical Therapy on IOP Control in Ghana. Ghana Med J. 2014 Sep;48(3):148-52.

Gyasi ME, Francis AW, Chen Y, et al. Presentation of glaucoma in the greater accra metropolitan area of ghana. Ghana Med J. 2014 Sep;48(3):143-7.

Hadigal SR, , Antoine TE, Yak-oub AM, Djalilian AR, Shukla D, et al. Heparanase is a host enzyme required for herpes simplex virus-1 release from cells. Nat Commun. 2015 Apr 27;6:6985.

Hall C, Wang S, McAnany JJ, et al. Effect of luminance noise on the object frequencies mediating letter identification. Front Psy-chol. 2014 Jul 3;5:663.

Hallak JA, Jassim S, Jain S, et al. Symptom burden of patients with dry eye disease: a four do-main analysis. PLoS One. 2013 Dec 13;8(12):e82805.

Haller JA, Stalmans P, MI-VI-TRUST Study Group [Mieler WF], et al. Efficacy of intravitreal ocriplasmin for treatment of vit-reomacular adhesion: subgroup analyses from two randomized trials. Ophthalmology. 2015 Jan;122(1):117-22.

Han J, Liu J, Yao X, et al. Por-table waveguide display system with a large field of view by inte-grating freeform elements and volume holograms. Opt Express. 2015 Feb 9;23(3):3534-49.

Han KY, Chang JH, Azar DT, et al. Involvement of lysosomal degradation in VEGF-C-in-duced down-regulation of VEGFR-3. FEBS Lett. 2014 Nov 28;588(23):4357-63.

Han KY, Chang JH, Azar DT, et al. Selective Binding of Endos-

tatin Peptide 4 to Recombinant VEGF Receptor 3 In Vitro. Protein Pept Lett. 2015;22(11):1025-30.

Han KY, Chang JH, Azar DT, et al. Evidence for the involvement of MMP14 in MMP2 processing and recruitment in exosomes of corneal fibroblasts. Invest Ophthalmol Vis Sci. 2014 Jul 11. [Epub]

He J, Cortina MS, Kakazu A, et al. The PEDF Neuroprotec-tive Domain Plus DHA Induces Corneal Nerve Regeneration After Experimental Surgery. Invest Ophthalmol Vis Sci. 2015 Jun;56(6):3505-13.

Hirata H, Rosenblatt MI. Hyper-osmolar tears enhance cooling sensitivity of the corneal nerves in rats: possible neural basis for cold-induced dry eye pain. Invest Ophthalmol Vis Sci. 2014 Aug 19;55(9):5821-33.

Hou JH, Prickett AL, Cortina MS, Jain S, de la Cruz J. Safety of femtosecond laser-assisted cataract surgery performed by surgeons in training. J Refract Surg. 2015 Jan;31(1):69-70.

Hou JH, Sivaraman KR, de la Cruz J, Lin AY, Cortina MS. His-topathological and immunohisto-chemical analysis of melt-associ-ated retroprosthetic membranes in the Boston type 1 keratopros-thesis. JAMA Ophthalmol. 2014 Sep;132(9):1133-6.

Hou JH, Tannan A, Sugar J, et al. Clostridium perfringens endophthalmitis after penetrating keratoplasty with contaminated corneal allografts: a case series. Cornea. 2015 Jan;34(1):23-7.

Hu J, Bui KM, Patel KH, Wilen-sky JT, Vajaranant TS, et al. Ef-fect of hemodialysis on intraocu-lar pressure and ocular perfusion pressure. JAMA Ophthalmol. 2013 Dec;131(12):1525-31.

Hu J, Goldstein DA, Leiderman YI, Malhotra V, Chau FY, Lin AY, Vajaranant TS. Epithelial downgrowth after Ahmed implan-tation presenting as a peritubular fibrovascular membrane. J Glau-coma. 2013 Aug;22(6):e11-3.

Hu J, Hoang QV, Chau FY, Blair MP, Lim JI. Intravitreal anti-vas-cular endothelial growth factor for choroidal neovascularization in ocular histoplasmosis. Retin Cases Brief Rep. 2014 Win-ter;8(1):24-9.

Huh ES, Aref AA, Vajaranant TS, de la Cruz J, Chau FY, Cortina MS. Outcomes of

pars plana glaucoma drainage implant in Boston type 1 kerato-prosthesis surgery. J Glaucoma. 2014 Jan;23(1):e39-44.

Huynh N, Blain D, Maumenee IH, et al. Systemic diagnostic testing in patients with appar-ently isolated uveal colobo-ma. Am J Ophthalmol. 2013 Dec;156(6):1159-1168.

Jain S, Aref AA. Senile Dementia and Glaucoma: Evidence for a Common Link. J Ophthalmic Vis Res. 2015 Apr-Jun;10(2):178-83.

Jain S, Patel RM, Lim J, Lee S, Setabutr P, Aakalu VK, et al. Cerebrospinal Fluid Leak Presenting as Epiphora. Ophthal Plast Reconstr Surg. 2014 Jun 6. [Epub]

Jaishankar D, Yakoub AM, Shuk-la D, et al. Characterization of a proteolytically stable d-Peptide that suppresses herpes simplex virus 1 infection: implications for the development of entry-based antiviral therapy. J Virol. 2015 Feb 1;89(3):1932-8.

Jeong S, Patel N, Gao X, et al. Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hyper-tension. Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2737-48.

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BOOKS AND CHAPTERS

Alio JL, Azar DT, Stasi K, Soria FA. Surgical correction of presbyopia. In: Yanoff M, Duker JS. Ophthalmology (4th ed). Pitts-burgh: Elsevier/Saunders, 2014.

Alio JL, Azar DT, Stasi K, Soria FA. Surgical correction of pres-byopia. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Alio JL, Azar DT. Difficult and complicated cases in refractive surgery. Berlin: Springer-Verlag, 2015.

Ang LPK, Azar DT. LASEK and Epi-LASIK. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refrac-tive Surgery. W B Saunders Co, 2014.

Ang LPK, Azar DT. Laser Subepithelial Keratomileusis (LASEK) and Epi-LASIK. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Aref AA, Vajaranant TS. Man-agement of glaucoma associ-ated with Boston KPro Type I implantation. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artificial Corneas: Funda-mentals and Surgical Applica-tions. Berlin: Springer-Verlag, 2015.

Aref AA, Varma, R, eds. Advanced Glaucoma Surgery. Basel: Birkhauser Verlag AG, 2015.

Aref AA. What are pearls for the postoperative management of trabeculectomy and its associ-ated complications? Curbside Consultation in Glaucoma: 49 Clinical Questions, 2nd ed. Gedde SJ, Panarelli JF, Lewis RA, Heuer DK, eds. Slack, Inc, 2015:193-196.

Assil KK, Hallak JA, Azar DT. Astigmatic and radial incisional keratotomy. In: Yanoff M, Duker JS. Ophthalmology (4th ed). Pitts-burgh: Elsevier/Saunders, 2014.

Assil KK, Hallak JA, Azar DT. Astigmatic and radial incisional keratotomy. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Azar DT. Clinical Optics. (Basic and clinical science course, Sec. 3) San Francisco, American

Academy of Ophthalmology & European Board of Ophthalmol-ogy, 2013.

Azar DT. Refractive surgery (Section Editor: Part 3). In: Yanoff M, Duker JS. Ophthalmology (4th ed.) Pittsburgh: Elsevier/Saun-ders, 2014.

Barnes SD, Hallak J, Pa-van-Langston D, Azar DT. Micro-bial keratitis (Ch 15). In: Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett’s Princi-ples and Practice of Infectious Diseases. 8th ed. Philadelphia, PA : Elsevier/Saunders, 2015.

Barnes SD, Kumar N, Pa-van-Langston D, Azar DT. Microbial conjunctivitis (Ch 14) In: Bennett JE, Dolin R, Blaser MJ. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA : Elsevier/Saun-ders, 2015.

Batta P, Wadia HP, Sugar J. Corneal and external eye man-ifestations of systemic disease. In: Yanoff M, Duker JS. Oph-thalmology (4th ed.) Pittsburgh: Elsevier/Saunders, 2014.

Bhasin A. Djalilian AR, Mova-hedan A. Integrated artificial corneas: current developments. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artificial Corneas: Fundamentals and Surgical Applications. Berlin: Springer-Verlag, 2015.

Bui KM, Leiderman YI. Photo-dynamic therapy for neovascular age-related macular degenera-tion. In: Lim JI, ed. Age-Related Macular Degeneration. 3rd rev. ed. Boca Raton: CRC Press/Tay-lor & Francis Group, 2013.

Chau FY, Wallace D, Vajaranant T, Herndon L, Lee PP, Challa P, Allingham R, Maumenee I. Osteogenesis Imperfecta and the eye. In: Shapiro JR, Byers PH, Glorieux FH, Sponseller PD (eds.) Osteogenesis Imperfecta: A Translational Approach to Brit-tle Bone Disease. Amsterdam: Academic Press, 2013.

Chow CC, Lim JI, Modi D, Kles-ert TR, Rosenfeld PJ. Anti-VEGF drugs and clinical trials. In: Lim JI, ed. Age-Related Macular Degeneration. 3rd rev. ed. Boca Raton: CRC Press/Taylor & Fran-cis Group, 2013.

Chow CC, Mieler WF, Mittra and RA, Pollack JS. Retinal arterial macroaneurysms . In: Yanoff M, Duker JS. Ophthalmology (4th

ed). Pittsburgh: Elsevier/Saun-ders, 2014.

Chow CC, Mieler WF, Mittra RA, Pollack JS. Retinal arterial mac-roaneurysms (Ch 27). In: Duker JS, Yanoff M, Bakri S. Yanoff & Duker’s Retina and Vitreous. W B Saunders Co, 2014.

Cortina MS, de la Cruz J, eds. Keratoprostheses and Artificial Corneas: Fundamentals and Surgical Applications. Berlin: Springer-Verlag, 2015.

Eslani M, Movahedan A, Djalilian AR. Gene therapy. In: Scorsetti DH, Perez VL, Gomes JA, eds. Stem Cells in Ophthal-mology. Philadelphia, PA: Jaypee Medical Inc.; 2015.

Espana EM, Djalilian AR. Yoo SH, Romano A. En Face Optical Coherence Tomography imaging of corneal limbal stem cell niche. (Ch 7). In: Lumbroso, Bruno. Clinical En Face OCT Atlas. New Delhi: Jaypee-Highlights, 2013.

Flower RW, Rathod R, Chau FY. Photocoagulation of AMD-asso-ciated CNV feeder vessels: An optimized approach. In: Lim JI, ed. Age-Related Macular Degen-eration. 3rd rev. ed. Boca Raton: CRC Press/Taylor & Francis Group, 2013.

Gandhi S, Jain S. The Anatomy and Physiology of the Cornea. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artificial Corneas: Fundamentals and Surgical Applications. Berlin: Springer-Verlag, 2015.

Ghanem RC, Allemann N, Azar DT. Phakic intraocular lenses. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Ghanem RC, Allemann N, Azar DT. Phakic intraocular lenses. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Goldstein DA, Patel SS Tessler HH. Episcleritis and scleritis. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Goldstein MH, Sugar J, Kelmen-son AT, Wadia HP, Edgington B. Anterior corneal dystrophies. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed) Pittsburgh: Elsevier/Saunders, 2014.

Güell JL, Arrondo E, Cortina MS, Echevarria J, Gómez-Resa

OneVision | 47

MV, Gris O, Hannush SB, Mateo C. Boston KPro Type I: Compli-cations. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artifi cial Corneas: Funda-mentals and Surgical Applica-tions. Berlin: Springer-Verlag, 2015.

Hou JH, Young JA, Kommehl EW, de la Cruz J. Preoperative evaluation for refractive surgery. In: Yanoff M, Duker JS. Oph-thalmology (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Hou JH, Young JA, Kommehl EW, de la Cruz J. Preoperative evaluation for refractive surgery. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Jain S, Tibrewal S, Kramarevsky N, Hardten DR. Excimer laser photorefractive keratectomy. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Jain S, Tibrewal S, Kramarevsky N, Hardten DR. Excimer laser photorefractive keratectomy. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Kang JJ, Cortina MS. Imaging of Boston Keratoprosthesis Type 1. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artifi cial Corneas: Fundamentals and Surgical Applications. Berlin: Springer-Verlag, 2015.

Kang JJ, Setabutr P. Ocu-loplastic Considerations in Boston Keratoprosthesis. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artifi cial Corneas: Fundamentals and Surgical Applications. Berlin: Springer-Verlag, 2015.

Knepper PA, Grybauskas A, Ku-prys P, Skuran K, Samples JR. Biomarkers to predict glaucoma surgical success In: Samples JR, Ahmed J (eds). Surgical Innovations in Glaucoma. New York, 2014. (p 287-294).

Kojima T, Primack JD, Azar DT. Intrastromal corneal ring seg-ments and collagen crosslinking. In: Yanoff M, Duker JS. Oph-thalmology (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Lee SH, Cortina MS, de la Cruz J. History of the Artifi cial Cornea. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artifi cial Corneas: Fundamentals

and Surgical Applications. Berlin: Springer-Verlag, 2015.

Lim JI, ed. Age-Related Macular Degeneration. 3rd rev. ed. Boca Raton: CRC Press/Taylor & Fran-cis Group, 2013.

Lim JI, Rosenblatt BJ, Benson WE. Diabetic Retinopathy (Ch 21). In: Duker, Jay S., Yanoff, Myron, and Bakri, Sophie. Yanoff & Duker’s Retina and Vitreous. W B Saunders Co, 2014.

Lim JI, Rosenblatt BJ, Benson WE. Diabetic retinopathy. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Lim JI. AMD for the Cataract Surgeon. In: Cataract Surgery and Retinal Disease: Optimizing Visual Outcomes. Editor: Dennis Han MD. 2013.

Lim JI. Neovascular age-related macular degeneration. In: Lim JI, ed. Age-Related Macular Degeneration. 3rd rev. ed. Boca Raton: CRC Press/Taylor & Fran-cis Group, 2013.

Mieler WF. Evidence-Based Medicine: The Prophylaxis and Treatment of Endophthalmitis. In: Kertes PJ, Johnson TM. Evi-dence-Based Eye Care (2nd ed.) Philadelphia: Lippincott Williams & Wilkins, 2014.

Mittra RA, Mieler WF. Drug toxicity of the posterior segment. In: Ryan, Stephen J. Retina. Lon-don: Saunders/Elsevier, 2013

Moss HE . Combined third, fourth and sixth nerve palsies. In: MedLink Neurology, Gilman, S (editor-in-chief), MedLink Corpo-ration, San Diego, 2013, 2014.

Moss HE. Alexia without agraph-ia. In: MedLink Neurology, Gil-man, S (editor-in-chief), MedLink Corporation, San Diego, 2014.

Moss HE. Cogan syndrome. In: MedLink Neurology, Gilman, S (editor-in-chief), MedLink Corpo-ration, San Diego, 2014.

Moss HE. Eye movement disor-ders. In: Neurological Differential Diagnosis, Ettinger AB, Weisbrot D (eds.), Cambridge University Press, 2014.

Moss HE. Horizontal gaze palsy. In: MedLink Neurology, Gilman, S (editor-in-chief), MedLink Cor-poration, San Diego, 2014.

Moss HE. Optic neuritis. In: Conn’s Current Therapy. 65th edition, Bope ET, Kellerman R

(eds.), Elsevier Saunders. 628-629, 2014.

Moss HE. Vertical gaze palsy. In: MedLink Neurology, Gilman, S (editor-in-chief), MedLink Corpo-ration, San Diego, 2013.

Patel RM, Putterman AM. Orbital Blowout Fractures. In: Ichhpujani P, Spaeth GL, Yanoff M, eds. Expert Techniques in Ophthalmic Surgery. New Delhi : Jaypee Brothers Medical Pub-lishers Ltd., 2015. pp 645-652.

Putterman AM. Pearls for Muller’s Muscle-Conjunctival Resection with Upper Bleph-aroplasty. (Chapter 191). In: Hartstein ME, Massry GG, Holds JB, eds. Pearls and Pitfalls in Cosmetic Oculoplastic Surgery. New York: Springer, 2015, p655-57.

Rao NK, Goldstein MH, Tu EY. Dry Eye. In: Yanoff M, Duker JS. Ophthalmology (4th ed). Pitts-burgh: Elsevier/Saunders, 2014.

Shorter ES, Beyer JE, McMa-hon TT. Boston KPro Type 1: The Role of the Contact Lens. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artifi cial Corneas: Fundamentals and Surgical Applications. Berlin: Springer-Verlag, 2015.

Sivaraman KR, Allemann N. Anterior Segment Consider-ations in Boston Type I Kerato-prosthesis. In: Cortina MS, de la Cruz J, eds. Keratoprostheses and Artifi cial Corneas: Funda-mentals and Surgical Applica-tions. Berlin: Springer-Verlag, 2015.

Srur L, Selkin RP, Azar DT, Marten L, Wang MX, Karp CL. Excimer Laser Treatment of Corneal Pathology. In: Yanoff M, Duker JS. Ophthalmology (4th ed). Pittsburgh: Elsevier/Saun-ders, 2014.

Sugar J, Batta P. Keratoconus and other ectasias. In: Yanoff M, Duker JS. Ophthalmology (4th ed.) Pittsburgh: Elsevier/Saun-ders, 2014.

Sugar J, Wadia HP, Vasaiwala RA. Congenital corneal anoma-lies. In: Yanoff M, Duker JS. Oph-thalmology (4th ed.) Pittsburgh: Elsevier/Saunders, 2014.

Sugar J, Wadia HP, Vasaiwala RA. Stromal corneal dystrophies. In: Yanoff M, Duker JS. Oph-thalmology (4th ed.) Pittsburgh: Elsevier/Saunders, 2014.

Taneri S, Mimura T, Azar DT. Current concepts, classifi cation, and history of refractive surgery. In: Yanoff M, Duker JS. Oph-thalmology (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Taneri S, Mimura T, Azar DT. Current concepts, classifi cation, and history of refractive surgery. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Tobaigy FM, Fahd D, Chamon W. Wavefront-based Excimer Laser Refractive Surgery. In: Yanoff M, Duker JS. Ophthalmol-ogy (4th ed). Pittsburgh: Elsevier/Saunders, 2014.

Tobaigy FM, Fahd D, Chamon W. Wavefront-based Excimer Laser Refractive Surgery. In: Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

Vajaranant TS, Aref AA. Pars Pana Tube Shunt Surgery in Keratoprosthesis. In: Aref AA, Varma, R, eds. Advanced Glau-coma Surgery. Basel: Birkhauser Verlag AG, 2015.

Walonker AF, Diddie KR, Niec M. Clinical research trials. In: Lim JI, ed. Age-Related Macular Degeneration. 3rd rev. ed. Boca Raton: CRC Press/Taylor & Fran-cis Group, 2013.

Wilensky, J, McGlynn RH. Late Bleb Leeks. In: Shaarawy, Tarek M. Glaucoma. (Vol. 2: Surgical management). London: Saun-ders Elsevier, 2015.

Yanoff M, Duker JS, Azar DT, Rosen ES. Yanoff & Duker’s Cataract and Refractive Surgery. W B Saunders Co, 2014.

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INVESTITURE OF WILLIAM F. MIELER, MD, FARVO FIRST RECIPIENT OF THE CLESS FAMILY PROFESSORSHIP IN OPHTHALMOLOGYOn November 18, 2014, Dr. William Mieler, Professor of Ophthalmology and Vice Chair for Education, was invested as the inaugural Cless Family Professor among members of the Cless Family, distinguished faculty and UIC Leadership. The Cless Family Professorship was established thanks to the generosity of the Cless Family Foundation. Endowed professorships are one of the highest honors bestowed by the academic community. Income from these funds provides research support and resources for program development that enable educators to pursue projects at the forefront of their fields.

Dr. Mieler is an expert in treating diseases of the macula, retina and vitreous. Throughout his stellar academic career Dr. Mieler has been involved in cutting edge research, published extensively, and demonstrated an outstanding commitment to education in ophthalmology. Dr. Mieler has received multiple awards from the American Academy of Ophthalmology. In 2013 the Macula Society awarded him the prestigious J. Donald Gass Medal for extraordinary contributions to diseases of the macula.

IN MEMORIUM

Dr. Mark Rosenblatt, Dr. William Mieler and Dean Dimitri Azar

GERHARD CLESS, a generous benefactor and longtime friend of the Department of Ophthalmology and Visual Sciences, passed away on Jan-uary 22, 2016, at the age of 75. Gerhard was an innovator, en-trepreneur and family man. Born and raised in Germany, Gerhard

met his wife Ruth of 51 years in 1960, after which they emigrated from Germany to Chicago. He co-founded Data Specialties, the forerunner to Lincolnshire based Zebra Technologies which developed the first barcode printers in the early 1980s.

Mr. Cless and his family have been generous supporters of the Department of Ophthalmology & Visual Sciences since 2000. The Cless Family Foundation funded an array of projects and needs for the department including vision research and education programs, support for acquisi-tions of advanced microscopy, recruitment of retina faculty, clinical studies in the diseases of the retina and macula, as well as support for a retina fellowship. Prior gifts also established the Gerhard Cless Endowed Lecture in 2003 and the Cless Best of the Best Award in 2008. The Cless Family Professorship in Ophthalmology was established in 2013, and most recently Gerhard and Ruth Cless made a transformative gift to establish the Cless Family Ophthal-mic Surgical Training and Simulation Center.

Mr. Cless is survived by his wife, Ruth; children, Martin (Kristin) Cless, Jennifer (Stephen) Zehr, Stephen (Anne) Cless and Bryan (Megan) Cless; and 10 grandchildren.

JOHN H. PANTON, MD, (Res’ 57) a long-time friend and gra-cious benefactor to the Department of Oph-thalmology and Visu-al Sciences, passed away on December 20, 2015. Mary Panton, John’s wife of 60 years, passed away in June, 2015. Together, they cherished both

their family and giving back in meaningful ways.

A 1950 graduate of the University of Athens Medical School, Dr. Panton completed his internship at Mercy Hos-pital-Loyola University and his residency in ophthalmology at the University of Illinois College of Medicine. Dr. Panton often credited his success to his UIC training.

He opened his practice in 1960, and in time was joined by two of his sons, Drs. Peter (Res ’86) and Robert Panton (Res ’90), and his daughter, Dr. Elizabeth Panton-Karkazis.

The Panton family have been giving to the Department of Ophthalmology since the 1980s. Their great generosity has benefited the Lions of Illinois Eye Research Institute, endowed professorships and most recently the Panton Family Professorship. In 2007, Peter and Robert Panton joined the children of three other resident alumni to es-tablish the Four Fathers Lecture in Ophthalmology. John and Mary Panton also supported the IEEI Library, and the Panton Family Scholarship in the College of Medicine.

John and Mary Panton are survived by their four children, Peter (Estelle) Panton, Evans (Laura) Panton, Robert (Marika) Panton, and Elizabeth (Frank) Karkazis; and 11 grandchildren.

CLESS FAMILY OPHTHALMIC SURGICAL TRAINING AND SIMULATION CENTERThe Illinois Eye and Ear Infirmary is known as a leader in the field of ophthalmic training in the region and in the nation. One component of this leadership is providing the highest level of surgical training that is available. This year we inaugurated the 9 station state-of-the-art Cless Family Ophthalmic Surgical Training and Simulation Center (Cless Lab), the premier center for ophthalmic surgical training in the Midwest. The Cless Lab will be home to surgical training courses, webcasting and live surgery streaming as well as surgical simulation technol-ogy. A generous investment made by the Cless Family Foundation, along with support from faculty and alumni, made this vision a reality. Establishing the Cless Lab is an enormous advancement in how we train our residents and surgical fellows. It is an active learning environment allowing for a virtual-reality simulation experience within which attention to the finest, most minute details, such as the careful orchestration of hand and foot instrument manipulation, can be perfected without putting patients at risk. It will no doubt significantly increase trainees’ aptitude and confidence when performing in a live operating room.

The virtual connections this equipment makes possible will enable us to examine how fellow surgeons from all corners of the world do work, and repeat it right here. This exposure to new information and practices will fuel the innovation and breakthroughs that will happen here first. And, when they do, we can share them with the rest of the world right from the Cless Lab. We now are able to provide services few places in the world can offer. Our faculty, residents, fellows, alumni and local ophthalmologists can learn more, innovate faster and pioneer surgical curriculum because of these connections.

LEADERSHIP

Left to right: Drs. Sugar, McMahon, Shahidi, Mieler and Rosenblatt—not pictured, Dr. Chan

Mark I. Rosenblatt, MD, PhD, MBA | Professor and Department HeadLions of Illinois/Charles I. Young Chair in Ocular Research

Joel Sugar, MD | Vice Chair for Clinical OperationsJoel Sugar MD Professor in Ophthalmology

William F. Mieler, MD, FARVO | Vice Chair for EducationCless Family Professor in Ophthalmology

Mahnaz Shahidi, PhD | Vice Chair for ResearchMorton F. Goldberg MD FACS Professor in Ophthalmology

Timothy McMahon, OD, FAAO | Vice Chair for OptometryProfessor of Ophthalmology

R. V. Paul Chan, MD, FACS | Vice Chair for Global Ophthalmology Professor of Ophthalmology

1 Leadership2 Shedding Light on the “Bionic Eye”4 Artificial Cornea Program Flourishes6 PROSE Clinic Makes Strides8 Stem Cells and Sight10 Clinical Services/Faculty28 Research Faculty32 Sponsored Research34 Clinical Investigations and Trials36 Giving38 Education40 Publications48 In Memoriam; Investiture49 Cless Lab

IN THIS ISSUE

CREDITSWritersLisa HoltonMargaret Doyle

Editor Laurie Walker

Designer Lisa Birmingham

Contributors Margaret Chervinko, Lauren Hughes, Cristina Lee, Kristen Scheurich, Laurie Walker

Photography Cathy Carroll, Joshua Clark, Roberta Dupuis-Devlin, Mark Janowicz

On the coverVisionary by Gwyn Newcombe

Department of Ophthalmology and Visual Sciences Illinois Eye and Ear Infirmary University of Illinois College of Medicine

1855 West Taylor StreetChicago, IL 60612

symposia & events 2016

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February 20-26, 2016 9th Annual Illinois Eye Review

Friday, April 22, 2016 9th Annual Retina Symposium

Wednesday, May 25, 2016 2016 Spring Glaucoma Symposium

Friday, June 17, 2016 40th Annual Alumni / Resident Day

Sunday, October 16, 2016Alumni Reception at the AAO Meeting

Saturday, October 22, 2016 The Chicago Chronic GVHD Meeting

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