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) Celerino Abad-Zapatero (Chicago, IL,USA 15 April

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Celerino Abad-Zapatero (Chicago, IL,USA

15 April

1

Wednesday, June 20th

AUDITORIUM Workshop on NEW and NOTABLE BIOPHYSICS Chairs: Nuno Santos and María García-Parajo

11:00-11:25 Manuela Pereira (ITQB Univ. Nova Lisboa, P) Structural basis for energy transduction by respiratory alternative complex III

11:25-11:50 Marco Manni (Institute Biofisika, Leioa ES) Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage

COFFEE BREAK

12:20-12:45 Maria João Ramos (Univ. Porto, P) Advances and pitfalls in computational enzymatic catalysis

12:45-13:10 Laura Martínez-Muñoz (CNB-CSIC, Madrid ES) Separating actin-dependent chemokine receptor nanoclustering from dimerization indicates a key role for clustering in CXCR4 signaling and function

13:30-15:30 REGISTRATION / LUNCH BREAK

AUDITORIUM Opening Ceremony

15:30-16:00 Welcome

AUDITORIUM Plenary Opening Lecture Chair: Vicente Aguilella

16:00-16:45 Sergey M. Bezrukov (NICHD-NIH, Bethesda MD, USA) Single-molecule biophysics: new insights into the dynamics of escape from potential and entropic traps

16:45-17:15 COFFEE BREAK (Poster and Exhibitor Hall)

6th Iberian / 10th IberoamericanBiophysics Congress

2

AUDITORIUM S0 Symposium on PHYSICS IN BIOLOGY Chairs: Antonio Alcaraz and Armindo Salvador

17:15-17:35 David Reguera (Univ. Barcelona, ES) Physical virology: how physics can help us understand viruses

17:35-17:55 Jorge Carneiro (Institute Gulbenkian, Oeiras, P) Time-lapse bioimage analysis solved as a cellular morphodynamics model fitting problem

17:55-18:15 Fèlix Ritort (Univ. Barcelona, ES) Experimental measurement of information-content in nonequilibrium systems

18:15-18:25 Horia Petrache (Indiana-Purdue Univ. IN, USA) Electrostatic charging of lipid membranes by ATP

18:25-18:35 Carmen Romero (Univ. Nacional Colombia, Bogotá) A comparative study between the limiting diffusion coefficients of α-amino acids and α,ω-amino acids in water and sodium chloride aqueous solutions at 298.15 K

18:35-18:45 Daniel Sánchez de Alcázar (CICbiomaGUNE, Donostia, ES) Nanostructured films based on CTPR proteins

18:45-18:55 Magdalena Kowacz (ITQB Univ. Nova Lisboa, P) Effect of infrared light on protein conformation, adhesion and enzymatic performance

18:55-19:05 Álvaro Martínez Monge (Univ. Barcelona, ES) Single-molecule characterization of heterogeneous DNA ensembles

19:05-19:15 Carla Huerta-López (CNIC, Madrid, ES) Titin hydrogels to examine emergent mechanical properties of striated muscle

AUDITORIUM Clarinet and piano concert (Sponsored by Small Biosystems Lab)

19:30-20:30

Antonio Amanti and Patrizia Marcatello 1. Clarinet Concerto No.1 in F minor transcribed to Piano by Carl Maria Von Weber 2. Sonata in B-Flat Clarinet and Piano by Francis Poulenc 3. Sholem-alekhem, Rov Feidman for Clarinet and Piano by Bela Kovacs

20:30-21:30 WELCOME RECEPTION

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

3

Thursday, June 21th

AUDITORIUM S1 Symposium on PROTEIN STRUCTURE, DYNAMICS AND FUNCTION Chairs: Irene Díaz-Moreno and Paula Gameiro

9:00-9:25 José María Delfino (Univ. Buenos Aires, ARG) Targeting the solvent accessible surface area (SASA) in proteins

9:25-9:35 Mar Pérez Ruiz (CNB-CSIC, Madrid, ES) Study of T7 core proteins involved in DNA ejection: gp15 and gp16

9:35-9:50 Lionel Rouzic (WYATT Technologies) The light scattering toolkit for characterization of proteins and other bio-macromolecules

9:50-10:00 Ernesto Roman (Univ. Buenos Aires, ARG) Thermodynamics and protein dynamics relation in a psychrophile protein

10:00-10:10 Ernesto Anoz-Carbonell (Univ. Zaragoza, ES) Regulation of FMN biosynthesis in homo sapiens: kinetics and thermodynamics of the riboflavin kinase activity

COFFEE BREAK (Poster and Exhibitor Hall)

10:40-11:05 Adriana Rojas (CICbioGUNE, Derio, ES) Subversion of endosomal sorting machinery by legionella pneumophila

11:05-11:15 Manuel Bano Polo (Univ. Valencia, ES) Transmembrane but not soluble helices fold far inside the ribosome tunnel

11:15-11:30 Hanna Mueller-Landau (Dynamic Biosensors, GmbH) Titin hydrogels to examine emergent mechanical properties of striated muscle

11:30-11:40 Enrique Marcos-Benteo (IRB Barcelona, ES) De novo design of protein structures for binding small-molecules and nucleosomal DNA

11:40-11:50 Ivo Martins (Univ. Lisboa, P) Zika virus capsid protein binds host lipid droplets via an auto-inhibitory mechanism

LECTURE HALL

S2 Symposium on MEMBRANE STRUCTURE AND FUNCTION (Sponsored by Chemistry and Physics of Lipids, published by Elsevier) Chairs: Manuel Prieto and Jesús Salgado

9:00-9:25 Senena Corbalán (Univ. Murcia, ES) C2 domain-containing proteins at the pre-synaptic space: rabphilin 3A as a paradigm.

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

4

9:25-9:40 Bárbara Claro (Univ. Porto, P) Biophysical experiments and molecular dynamics simulation of self-assembling cyclic peptide nanotubes at biological model membranes

9:40-9:55 Aurora Dolz (Delft Univ. NL) Free-standing membranes inside microfluidic devices and their use for the study of membrane nanotubes

9:55-10:10 Esperanza Rivera-de-Torre (Univ. Complutense, Madrid, ES) Single cysteine mutants of actinoporins sticholysins I and II as tools for the study of membrane heteropores assembly

COFFEE BREAK (Poster and Exhibitor Hall)

10:40-11:05 Antônio José da Costa Filho (Univ São Paulo, BR), Sponsored by ISMAR Subversion of endosomal sorting machinery by legionella pneumophila

11:05-11:20 Tania Cunha Branco Santos (Univ. Lisboa, P) The impact of atypical sphingolipids on the biophysical properties of model and cell membranes

11:20-11:35 José Lopes de Araújo (Univ. Porto, P) Siramesines anticancer activity: a biophysical approach

11:35-11:50 Victor Levadny (Russian Acad. Sci. Moscow, RU) Modeling of initial stage of antimicrobial peptide magainin 2 pore formation in lipid vesicles

AUDITORIUM Plenary RSEF-SBE Lecture Chair: Antonio Ferrer Montiel

12:00-12:45 Jordi García-Ojalvo (Univ. Pompeu Fabra, Barcelona, ES) Electrical signaling in bacteria

13:00-15:00 LUNCH BREAK

AUDITORIUM S3 Symposium on CHANNELS, RECEPTORS AND TRANSPORTERS Chairs: João Morais Cabral and Francisco Barros

15:00-15:25 Cecilia Bouzat (INIBIBB, Bahía Blanca, ARG) Molecular function of α7 nicotinic receptors

15:25-15:50 Juan Antonio Rosado (Univ. Extremadura, ES) Fine-tuning of store-operated Ca2+ entry by SARAF and EFHB

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

5

15:50-16:05 Ekaterina M. Nestorovich (CUA, Washington DC, USA) Analysis of anthrax toxin channel current fluctuational dynamics

16:05-16:20 Javier Garcia Nafria (Medical Research Council, Cambridge, UK) Structures of GPCR-G protein complexes by volta phase plate electron cryo-microscopy

COFFEE BREAK (Poster and Exhibitor Hall)

16:50-17:15 Cristina Paulino (Univ. Gröningen, NL) Anion conduction and gating in the calcium-activated chloride-channel TMEM16A

17:15-17:30 José Manuel González Ros (IBMC-UMH, Elche, ES) Modulation of the KcsA potassium channel by anionic phospholipids: role of the non-annular arginines

17:30-17:45 Paula Giménez Mascarell (CICbioGUNE, Derio, ES) Structure of the CNMP domain of the magnesium transport mediator CNNM4.

17:45-18:00 María Lourdes Renart Pérez (Univ. Miguel Hernández, Elche, ES) Exploring potassium channels selectivity and inactivation through steady-state and time-resolved fluorescence spectroscopy

LECTURE HALL S4 Symposium on CELLULAR BIOPHYSICS Chairs: Teresa Giráldez and Graça Soveral

15:00-15:25 Ana Salomé Veiga (Univ. Lisboa, P) Unravelling the activity and mechanism of action of PEPR, a viral-derived membrane-active peptide, against staphylococcus aureus biofilms

15:25-15:50 Sonia Contera (Oxford Univ., UK) Multiscale viscoelasticity of living systems

15:50-16:05 Catarina Sousa Lopes (Univ. Lisboa, P) Changes on elasticity and morphology of erythrocytes from amyotrophic lateral sclerosis patients

16:05-16:20 Fèlix Campelo (ICFO, Barcelona, ES) Biophysical mechanisms of collagen export from the endoplasmic reticulum

COFFEE BREAK (Poster and Exhibitor Hall)

16:50-17:15 Ana Xavier Carvalho (Univ. Porto, P) Exploring myosins roles during cytokinesis

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

6

17:15-17:30 Mariola Chacón-Rodríguez (Tech. Univ. Dresden, G) Meiotic nuclear oscillations are necessary to avoid excessive chromosome associations

17:30-17:45 Mário R. Felício (Univ. Lisboa, P) Antimicrobial peptides PAMAP2 and PAMAP1.9 reveal anticancer activity

17:45-18:00 Marta Gironella (Univ. Barcelona, ES) Relaxational kinetics in red blood cell mechanics: linking physical to biological aging

AUDITORIUM Plenary LAFeBS Lecture Chair: Juan Carmelo García

18:15-19:00 Rosangela Itri (Univ. Sao Paulo, BR) Photo-oxidation in membrane and cell biophysics: combining fluorescence, X-ray scattering (SAXS) and microscopy techniques

19:00-20:00 POSTER PARTY (Discussion of odd-numbered posters)

20:00-20:30 SBE General Assembly and Election Assembly (AUDITORIUM)

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

7

Friday, June 22th

LECTURE HALL

S5 Symposium on NUCLEIC ACIDS AND SUPRAMOLECULAR COMPLEXES Chairs: Eurico Cabrita and José López-Carrascosa

9:00-9:25 Ana M. Melo (Univ. Lisboa, P) Exploring the conformational plasticity of tau-tubulin complex by single-molecule FRET: insights into function of a dysfunctional protein

9:25-9:50 Pablo Chacón (IQFR-CSIC, Madrid, ES) Fitting tools for integrative structural biology

9:50-10:15 Ana Luisa Carvalho (Univ. Nova Lisboa, P) Investigating the carbohydrate preferences of cellulolytic bacteria

10:15-10:30 Maria I. Dauden (EMBL, Heidelberg, G) Molecular architecture of the elongator catalytic sub-complex and its tRNA interaction

10:30-10:45 Borja Ibarra (IMDEA Nanociencia, Madrid, ES) Mechanism of SSB displacement by the human mitochondrial DNA polymerase during lagging strand synthesis

10:45-11:00 Julene Madariaga (CNB-CSIC, Madrid, ES) Characterizing protein (un)binding rates at the single-molecule level using lateral magnetic tweezers combined with TIRF microscopy

AUDITORIUM S6 Symposium on COMPUTATIONAL AND SYSTEM BIOPHYSICS Chairs: Óscar Millet and Claudio Soares

9:00-9:20 José García de la Torre (Univ. Murcia, ES) Prediction of solution properties of globular and partially disordered proteins and nucleic acids

9:20-9:40 José M. Vilar (UPV-EHU, Bilbao, ES) Prediction and inference in complex biophysical systems

9:40-10:00 Manuel Melo (Univ. Nova Lisboa, P) The light scattering toolkit for characterization of proteins and other bio-macromolecules

10:00-10:15 Vicent Moliner (Univ. Jaume I, Castellón, ES) QM/MM theoretical studies of enzyme catalyzed reaction

10:15-10:30 Hugo Filipe (Univ. Coimbra, P)

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

8

Quantitative assessment of methods often used to obtain rate constants from biomolecular simulations translocation of cholesterol across a lipid bilayer

10:30-10:45 Gerardo Félix (UAM, Mexico DF) Influence of the intracellular calcium buffering properties on the secretory response of a human pancreatic beta-cell

10:45-11:00 Sergio Martí (Univ. Jaume I, Castellón, ES) Computational study of the retro-aldol de novo designed enzymes

11:00-11:30 COFFEE BREAK (Poster and Exhibitor Hall)

AUDITORIUM Plenary Lecture Chair: José Miguel Mancheño

11:30-12:00 Celerino Abad-Zapatero (Univ. Illinois, Chicago IL, USA) From altar boy to sorcerers apprentice: biophysics and beyond

12:00-13:00 POSTER PARTY (Discussion of even-numbered posters)

13:00-15:00 LUNCH BREAK

AUDITORIUM AWARDS SYMPOSIUM Chairs: Jesús Pérez-Gil and Nuno Santos

15:00-15:15 INTRODUCTION

15:15-15:45 F. Javier Luque (Univ. Barcelona, ES) Exploring the molecular determinants of ligand recognition and binding: from chemical structure to mechanisms of drug action

15:45-16:15 Pere Roca-Cusachs (IBC, Barcelona, ES) Sensing matrix rigidity: transducing mechanical signals from integrins to the nucleus

16:15-16:45 Marta Coimbra Marques (Univ. Lisboa, P) Thermodynamics and protein dynamics relation in a psychrophile protein

16:45-17:15 Joan Camuñas (Stanford Univ., Stanford CA, USA) From single molecule to single cell: the power of one

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com

9

17:30-18:00 COFFEE BREAK (Poster and Exhibitor Hall)

AUDITORIUM Plenary Closing Lecture Chair: Félix Ritort

18:00-18:45 Frederick C. Mackintosh (Rice Univ., Houston TX, USA) Phase transitions and the principle of detailed balance in living systems

19:00-19:30 AWARDS AND CLOSING CEREMONY (AUDITORIUM)

20:30 Bus Departure from Hotel LUZ

21:00-23:00 Congress Dinner in Benicassim (Palasiet Club Restaurant)

23:30 Bus Departure from Restaurant to Hotel LUZ

Castellón, 20 - 22 June Detailed Programmewww.sbe2018.com