synthesis of 2-substituted pyridines via a regiospecific alkylation, alkynylation, and arylation of...
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2007
Pyridine derivativesR 0380 Synthesis of 2-Substituted Pyridines via a Regiospecific Alkylation, Alkynylation,
and Arylation of Pyridine N-Oxides. — The title reaction allows the preparation of a variety of substituted pyridines. In the case of aliphatic Grignard reagents, the prod-ucts [cf. (IIIb) and (IIIe)] are formed with only modest yields. — (ANDERSSON, H.; ALMQVIST*, F.; OLSSON, R.; Org. Lett. 9 (2007) 7, 1335-1337; Org. Chem., Umeaa Univ., S-901 87 Umeaa, Swed.; Eng.) — R. Steudel
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