The Wollman lab measures models and manipulates signaling activities at the single-cell level to understand Dynamic Cellular Information Processing We strive to understand cellular decision-making biological variation and biological noise using

multidisciplinary approaches We develop methods in single-cell uorescence microscopy in combination with computational image analysis to evaluate the distribution of cellular responses in real-time We use mathematical modeling based on signaling pathway

mechanisms to infer and predict the details of mechanistic cellular signaling We experimentally investigate a cellular signaling system by manipulating the internal and external cellular environment both spatially and temporally at the single-cell level Specic

approaches include microuidic devices genetic and pharmaceutical perturbations and optogenetics

COMPUTATIONAL AND SYSTEMS BIOLOGY SEMINAR SERIES

ldquoCellular Variability and Information Flow in Signal Transduction Networksrdquo

Computational amp Systems Biology Track

Roy Wollman PhD University of California at Los Angeles

Lunch with speaker to follow in ND11 atrium

JUNE 1811AM - 12PM

ND11218