table of contents - naspghan...of an educational activity are required to disclose relevant...

Table of Contents

GENERAL INFORMATION General Information........................................................................................................................... 3 Program Committee/CME ................................................................................................................. 4 Program Overview............................................................................................................................. 7 Corporate Support.............................................................................................................................. 9 Future Dates ....................................................................................................................................... 10 Teaching and Tomorrow Participants ................................................................................................ 11 Satellite Symposia.............................................................................................................................. 13 Committee Schedule .......................................................................................................................... 15 NASPGHAN Committees ................................................................................................................. 17 THURSDAY, NOVEMBER 13, 2008 Exhibits/Poster Session I/ Welcome Reception ................................................................................. 21 FRIDAY, NOVEMBER 14, 2008 Plenary Session I................................................................................................................................ 27 Plenary Session II .............................................................................................................................. 28 Poster Session II / LUNCH................................................................................................................ 29 Concurrent Session I .......................................................................................................................... 39

A. Controversies in the Treatment of Chronic Hepatitis B. Management of Hepatitis C C. Oral Abstracts and RIG Symposium

Concurrent Session II......................................................................................................................... 43

A. New Clinical Updates B. Advanced Endoscopic Techniques C. Oral Abstracts Presentations – Liver and Translational Issues

SATURDAY, NOVEMBER 15, 2008 Poster Session III ............................................................................................................................... 47 Concurrent Session III ....................................................................................................................... 53

A. New NASPGHAN Guidelines: The current status B. Management of Portal Hypertension C. Oral Abstracts Presentations – Intestine/Colon/IBD

1

Saturday – continued Concurrent Session IV ....................................................................................................................... 57

A. Aerodigestive Approaches to Dysphagia and Aspiration B. Post Transplant Gastrointestinal Complications C. Oral Abstract Presentations – Nutrition/CF

Clinical Challenge Luncheons ........................................................................................................... 61 Concurrent Session V ........................................................................................................................ 63

A. IBD – Clinical Scenarios B. Antibiotic Therapy in GI Disease C. Oral Abstract Presentations – Esophagus/Stomach

Concurrent Session VI ....................................................................................................................... 67

A. Billing and Coding 101/102 B. Education 2008: Simulation C. Research Mentoring/Career Development

Exhibitor Listing and Product Descriptions....................................................................................... 69 Author Index ...................................................................................................................................... 77

2

NASPGHAN - CDHNF Clinical and Scientific Conference 2008

November 13 – 15, 2008 “Celebrating a Decade of Progress”

General Information

Educational Mission Statement: The education mission of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition is to: • Advance understanding of normal development, physiology and pathophysiology of diseases of the

gastrointestinal tract, liver and nutrition in children. • Improve professional competence, quality of care, and patient outcomes by disseminating knowledge

through scientific meetings, professional and public education. Our activities, education, and interventions will strive to use Adult Learning Methods (ALM) designed to improve competence, practice performance, and patient outcomes in measurable ways. These educational activities will be targeted to pediatric gastroenterologists, physicians with an expertise in pediatric gastroenterology, hepatology and nutrition, subspecialty fellows in pediatric gastroenterology, and nurses specializing in pediatric gastroenterology, hepatology and nutrition. Meeting Objectives: To improve clinical competence and performance through: 1. Identifying new science, new clinical treatments, and new NASPGHAN guidelines, related to a variety of gastroenterological disease states 2. Delineating diagnostic characteristics in difficult pediatric cases 3. Comparing treatment method controversies in chronic hepatitis, portal hypertension and other chronic gastrointestinal disorders 4. Discussing new findings in autoimmunity and the digestive tract interactions 5. Reviewing advanced endoscopic techniques 6. Updating knowledge on post-transplant gastrointestinal complications 7. Explaining scientific funding and clinical billing concerns Registration Hours Registration is located in the Bayview Foyer on the 1st floor and is open during the following hours: Tues, Nov 11 4:00pm – 6:00pm Wed, Nov 12 7:00pm – 6:00pm Thurs, Nov 13 7:00am – 6:00pm

Fri, Nov 14 7:00am – 5:00pm Sat, Nov 15 7:00am – 5:00pm

Exhibit Hours Exhibits are located in the Pavilion. The exhibits are open during the following hours: Thurs, Nov 13 5:00pm – 7:00pm Fri, Nov 14 11:30am – 4:00pm Sat, Nov 15 7:30am – 12:00noon

3

2008 Program Committee

John Barnard, MD Columbus, OH (NASPGHAN President) William Balistreri, MD Cincinnati, OH (CDHNF President) B Li, MD Milwaukee, WI (NASPGHAN President-Elect) Program Committee Chair Laurie Fishman, MD Boston, MA (Chair, Professional Education Committee) Alan Leichtner, MD Boston, MA (Chair, Training Committee) Ivor Hill, MD Wake Forest, NC (NASPGHAN Secretary-Treasurer)

Jenifer Lightdale, MD Boston, MA (Chair, Endoscopy Committee) Karen Murray, MD Seattle, WA (Chair, Professional Development Committee) John Pohl, MD Temple, TX (Co-Course Director, Postgraduate Course)

D. Brent Polk, MD Nashville, TN (Chair, Research Committee) Steve Schwarz, MD New York, NY (Chair, Clinical Practice Committee) Menno Verhave, MD Boston, MA (CDHNF Secretary-Treasurer)

CME Information NASPGHAN is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. AMA PRA Statement NASPGHAN designates this educational activity for a maximum of 13.58 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity Program evaluation It is NASPGHAN policy to conduct post activity evaluations. The results of these evaluations play a major role in planning future CME activities and are shared with faculty presenters. Faculty Disclosure In order to ensure independence, objectivity and scientific rigor in all activities and in accordance with the ACCME, ANCC and ACPE Standards for Commercial Support; all those in a position to control the content

4

of an educational activity are required to disclose relevant financial relationships. This includes indicating that one has nothing to disclose. Disclosure information will be distributed to the activity attendees. Prior to the program, all persons involved in the development or presentation of course content are expected to disclose any relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services consumed by, or used on, patients and related to the content of their presentations. All conflicts have been resolved satisfactorily.

First Last Disclosure

Estella Alonso No relationship to disclose Thomas Attard No relationship to disclose William Balistreri No relationship to disclose John Barnard No relationship to disclose Brad Barth No relationship to disclose William Berquist No relationship to disclose Bengt Bjorksten BioGaia Inc - Consultant/Scientific Advisor

Nestle – Speaker’s Bureau Danone – Speaker’s Bureau

Athos Bousvaros Abbott Pharmaceuticals - Speaker's Bureau Abbott Pharmaceuticals - Grant/Research Support Merck Pharmaceuticals - Grant/Research Support

Jeffrey Burns No relationship to disclose Gisela Chelimsky No relationship to disclose Stanley Cohen Given Imaging - Grant/Research Support, Consultant/Scientific Advisor

Olympus - Grant/Research Support Stephen Collins No relationship to disclose Lee Denson Genentech - Grant/Research Support Chris Dickinson No relationship to disclose Carol Durno No relationship to disclose Steve Erdman No relationship to disclose Michael Farrell No relationship to disclose William Faubion No relationship to disclose George Ferry No relationship to disclose Laurie Fishman No relationship to disclose Deborah Freese No relationship to disclose Glenn Furuta No relationship to disclose Richard Grand No relationship to disclose Frank R Greer No relationship to disclose David Gremse No relationship to disclose Anne Griffiths No relationship to disclose Sandeep Gupta GSK -Consultant/Scientific Advisor

Abbott - Speaker's Bureau TAP - Speaker's Bureau

Neera Gupta No relationship to disclose Eric Hassall AstraZeneca - Grant/Research Support

TAP Pharmaceutical Products - Consultant/Scientific Advisor James Heubi No relationship to disclose Edward Hoffenberg Centocor - Grant/Research Support

Abbott - Grant/Research Support Sherry Huang No relationship to disclose Christopher Jolley No relationship to disclose Nicola Jones No relationship to disclose

5

Binita Kamath No relationship to disclose Saul Karpen No relationship to disclose Ajay Kaul No relationship to disclose John Kerner No relationship to disclose Samuel Kocoshis No relationship to disclose Alan Leichtner No relationship to disclose B Li No relationship to disclose Chris Liacouras No relationship to disclose Jenifer Lightdale No relationship to disclose Simon Ling No relationship to disclose Petar Mamula No relationship to disclose Sonia Michail No relationship to disclose Adrian Miranda No relationship to disclose Naveen Mittal No relationship to disclose Hayat Mousa Takeda Pharmaceuticals - Speaker's Bureau Karen Murray No relationship to disclose Michael Narkewicz No relationship to disclose Vicky Ng No relationship to disclose Richard Noel No relationship to disclose Samuel Nurko No relationship to disclose Judith O'Connor No relationship to disclose Bankole Osuntokun No relationship to disclose Ashish Patel No relationship to disclose Mark Pimentel Salix Pharmaceuticals - Grant/Research Support;

Consultant/Scientific Advisor Movetis - -Consultant/Scientific Advisor Lilly - Grant/Research Support

John Pohl No relationship to disclose D Brent Polk No relationship to disclose Patricia Robuck No relationship to disclose Rachel Rosen No relationship to disclose David Rudnick No relationship to disclose Colin Rudolph No relationship to disclose Jeffrey Rudolph No relationship to disclose Rinarani Sanghavi Sucampo Pharmaceuticals - Grant/Research Support Kathleen Schwarz BMS - Grant/Research Support

Roche - Grant/Research Support Gildead - Grant/Research Support Novartis - Consultant/Scientific Advisor

Sarah Jane Schwarzenberg No relationship to disclose Eric Sibley No relationship to disclose Ronald Sokol Yasoo Health, Inc. - Consultant/Scientific Advisor Manu Sood No relationship to disclose Shikha Sundaram No relationship to disclose Grzegorz Telega No relationship to disclose vasundhara tolia No relationship to disclose Troy Torgerson No relationship to disclose Harland Winter No relationship to disclose Stavra Xanthakos No relationship to disclose Nada Yazigi No relationship to disclose Nader Youssef No relationship to disclose Qian Yuan No relationship to disclose

6

NASPGHAN – CDHNF Clinical and Scientific Conference Program Overview

November 13 – 15, 2008 THURSDAY, NOVEMBER 13, 2008 5:00pm – 7:00pm Exhibits/Poster Session I/ Pavilion

Welcome Reception FRIDAY, NOVEMBER 14, 2008 8:00am Plenary Session I Grand Ballroom 9:50am BREAK 10:30am Plenary Session II Grand Ballroom 12:15pm – 2:00pm Poster Session II / Lunch Pavilion 2:00pm – 3:30pm Concurrent Session I

A. Controversies in the Treatment of Chronic Hepatitis Grand Ballroom A

B. Management of Hepatitis C Grand Ballroom B

C. Oral Abstracts and RIG Symposium Seabreeze

3:30pm – 5:00pm Concurrent Session II

A. New Clinical Updates Grand Ballroom A

B. Advanced Endoscopic Techniques Grand Ballroom B

C. Oral Abstracts Presentations – Liver and Translational Issues Seabreeze

6:00pm – 8:00pm Practitioners Forum Grand Ballroom A

6:00pm – 8:00pm Training Directors and Division Heads Meeting Seabreeze

7

SATURDAY, NOVEMBER 15, 2008 7:00am – 9:00am Poster Session III Pavilion 8:30am – 10:00am Concurrent Session III

A. New NASPGHAN Guidelines: The current status Grand Ballroom A

B. Management of Portal Hypertension Grand Ballroom B

C. Oral Abstracts Presentations – Intestine/Colon/IBD Seabreeze

10:30am – 12:00pm Concurrent Session IV

A. Aerodigestive Approaches to Dysphagia and Aspiration Grand Ballroom A

B. Post Transplant Gastrointestinal Complications Grand Ballroom B

C. Oral Abstract Presentations – Nutrition/CF Seabreeze

12:00pm Clinical Challenge Luncheons See ticket

1:30pm – 3:00pm Concurrent Session V

A. IBD – Clinical Scenarios Grand Ballroom A

B. Antibiotic Therapy in GI Disease Grand Ballroom B

C. Oral Abstract Presentations – Esophagus/Stomach Seabreeze

3:15pm – 4:45pm Concurrent Session VI

A. Billing and Coding 101/102 Grand Ballroom A

B. Education 2008: Simulation Grand Ballroom B

C. Research Mentoring/Career Development Seabreeze 5:00pm NASPGHAN/CDHNF Business Meeting Grand Ballroom A

& Awards Ceremony 7:00pm CDHNF 10th Anniversary Celebration

Reception Lanai Dinner Grand Ballroom

8

CDHNF-NASPGHAN

Clinical and Scientific Conference “Celebrating a Decade of Progress”

Corporate Supporters

(As of October 20, 2008)

Shire US Takeda

Joli Diagnostic Inc

Given Imaging National Institutes of Health, NIDDK

Olympus

Prometheus Laboratories Mead Johnson Nutritionals

Nationwide Children’s Hospital

9

FUTURE NASPGHAN MEETING DATES

2009 NASPGHAN Meetings

2009 Annual Meeting and Postgraduate Course November 12 – 15, 2009 Gaylord National Hotel National Harbor, MD

2009 Fellow Conferences

1st Year Fellows Conference January 22 – 25, 2009 Ft. Lauderdale, FL Supported by a restricted grant from Nestle Nutrition Institute 2nd Year Fellows Conference March 12 - 15, 2009 Scottsdale, AZ Supported by a restricted grant from Abbott Nutrition 3rd Year Fellows Conference March 26 – 29, 2009 Scottsdale, AZ Supported by a restricted grant from Mead Johnson Nutritionals

10

TEACHING AND TOMORROW PROGRAM

PROGRAM PARTICIPANTS

A generous grant from SHIRE US allows NASPGHAN to bring the best and the brightest pediatric residents in North America to San Diego. The residents listed below will participate in an outstanding program of stimulating educational activities and social interactions throughout the conference.

Lusine Ambartsumyan, Philadelphia, PA

Akihiro Asai, New York, NY

James Bayrer, San Francisco, CA

Violina Bhattacharyya, Miami Beach, FL

Russell Cameron, New York, NY

Scott Cameron, Vancouver, BC

Monique Choquette, Cincinnati, OH

Lanla Conteh, Cleveland, OH

Liz Dancel, Greenville, SC

Runa Diwadkar, Savannah, GA

Steven Eagle, Teaneck, NJ

Osama El-Assal, Gahanna, OH

Abdul Elkadri, Amherst, NY

Gustave Falciglia, Chicago, IL

Amy Feldman, Philadelphia, PA

Katherine Furman, Charlottesville, VA

Candice Gabriel, Norfolk, VA

Diana Greyz, Chicago, IL

Dyer Heintz, Dallas, TX

Suchitra Hourigan, Baltimore, MD

Genie Kahn, Gainesville, FL

Sara Karjoo, Pittsburgh, PA

Ali Khalili, New Orleans, LA

Sarah Kinder, Chicago, IL

Thomas Krupica, Baltimore, MD

Soma Kumar, Columbus, OH

Sarah Majcina, Baltimore, MD

Danny Mallon, Seattle, WA

Satsuki Matsumoto, Iowa City, IA

Barbara McElhanon, Philadelphia, PA

Brian McFerron, Indianapolis, IN

Amanda Muir, Philadelphia, PA

Nikhil Pai, Toronto, ON

Dana Patton, San Francisco, CA

Wendy Pavlovich, Jamaica Plain, MA

Yen Pham, Houston, TX

Kerry Jo Powers, Los Angeles, CA

Esther Prince, Rochester, NY

Bryan Rudolph, New York, NY

Samuel Ruskin, Chicago, IL

Vesta Salehi, New York, NY

Cathy Sampert, Lacey, WA

Jason Silverman, Halifax, NS

Dellys Soler, Miami, FL

Sheria Spain, Columbus, OH

Khoa Tran, West Hartford, CT

David Troendle, Garland, TX

Anne Tsampalieros, Ottawa, ON

Victor Uko, Cleveland, OH

Pamela Valentino, Montreal, PQ

Jennifer Vittorio, Arlington, VA

Joshua Warolin, Fresno, CA

Elisa Wershba, Phoenix, AZ

Jennifer Woo, Los Angeles, CA

Sandra Wright, Birmingham, AL

George Zacur, Miami, FL

11

NOTES

12

SATELLITE SYMPOSIA

The Customer Link Satellite Symposium

FRIDAY, NOVEMBER 14, 2008 6:30 PM - REGISTRATION AND DINNER 7:00 PM-8:30 PM - SYMPOSIUM

GRAND BALLROOM C, SHERATON SAN DIEGO HOTEL AND MARINA, SAN DIEGO, CA

Program Title: Your Revised Guide to Pediatric GERD: Issues and Insights in Diagnosis and Management

7:00 PM Validity and Clinical Applicability of GERD Symptom Questionnaires in Children Suzanne P. Nelson, MD, MPH Assistant Professor of Clinical Pediatrics Feinberg School of Medicine Northwestern University Children’s Gastroenterology Specialists Chicago, IL 7:20 PM New Diagnostic Modalities in Pediatric GERD Samuel Nurko, MD, MPH Associate Professor of Pediatrics Harvard Medical School Director, Center for Motility and Functional Gastrointestinal Disorders Children’s Hospital Boston Boston, MA 7:40 PM Controversies in Eos Esophagitis Chris A. Liacouras, MD Associate Professor, Pediatrics University of Pennsylvania School of Medicine Attending Physician, Pediatric Gastroenterology Co-Director, Department of Endoscopy Medical Director of Clinical Trials Children’s Hospital of Philadelphia Philadelphia, PA 8:00 PM Pediatric Reflux in Flux: New Data, Definitions, and Guidelines Eric Hassall MB ChB, FRCPC, FACG Professor of Pediatrics, Division of Gastroenterology University of British Columbia BC Children's Hospital Vancouver, British Columbia 8:20 PM Question-and-Answer Session This activity is supported by an educational grant from Takeda Pharmaceuticals North America, Inc.

13

SATELLITE SYMPOSIA

Pediatric Application of PillCam® Capsule Endoscopy

Saturday, November 15, 2008

6:30 am – 8:00 am Breakfast will be served

The Sheraton San Diego Hotel & Marina Room: Harbor 1

1380 Harbor Island Drive San Diego, California 92101

Faculty

Speakers: Ari Bergwerk, MD

Medical Advisor, Given Imaging

Stanley Cohen, MD Children’s Center for Digestive Healthcare

Atlanta, Georgia

Ernest Seidman MD, FRCPC, FACG Professor of Medicine and Pediatrics McGill University, Montreal, Canada

This activity is support This activity is supportedby an educational grant from Given Imaging

14

NASPGHAN Committee Schedule Wednesday, November 12, 2008

12am – 4pm CDHNF Board Meeting Executive Boardroom

1pm – 6:30pm Impedance Work Group Room 511

4pm – 5pm Nutrition Committee Room 411

4pm – 5pm Fellow’s Committee Room 415

4pm – 6pm NASPGHAN Executive Council Meeting Executive 3AB

6pm – 10pm NASPGHAN Cmte Chair / Council Meeting Executive 3AB

Friday, November 14, 2008

7am – 8am Clinical Care & Quality Committee - Breakfast Meeting Executive Center 2B

7am – 8am Endoscopy & Procedures Committee – Breakfast Meeting Executive Center 2A

7am – 8am Ethics Committee – Breakfast Meeting Room 411

7am – 8am International Committee – Breakfast Meeting Room 415

7am – 8am JPGN Editorial Board Mtg – Breakfast Meeting Room 511

7am – 8am Professional Development Committee – Breakfast Meeting Room 514

7am – 8am Professional Education Committee – Breakfast Meeting Marina 6

7am – 8am Training Guideline Task Force – Breakfast Meeting Room 515

12pm – 1pm Training Guideline Steering Committee – Lunch Meeting Executive Center 1

12pm – 1:30pm Publications Committee Presidential Suite

6:00pm – 8:00pm Training Program Directors Meeting Grand Ballroom A

6:00pm – 8:00pm Practitioner’s Forum Meeting Seabreeze


7am – 8am Advocacy Committee – Breakfast Meeting Executive 2B

7am – 8am Finance Committee – Breakfast Meeting Room 514

7am – 8am IBD Committee – Breakfast Meeting Marina 6

7am – 8am Neurogastroenterology & Motility Committee – Breakfast Mtg Room 511

7am – 8am Public Education Committee – Breakfast Meeting Room 515

7am – 8am Research Committee – Breakfast Meeting Executive Center 2A

7am – 8am Training Committee – Breakfast Meeting Marina 3

15

NASPGHAN Committees As of October 2008

Officers President John A. Barnard, MD (‘08) Columbus, OH

President-Elect B UK Li, MD (‘08) Milwaukee, WI

Past-President Philip M. Sherman, MD (‘08) Toronto, ON

Secretary-Treasurer Ivor D. Hill, MD (‘08) Winston-Salem, NC Incoming Secretary-Treasurer David Gremse, MD (‘11) Las Vegas, NV Executive Council Estella Alonso, MD (‘09) Chicago, IL Judith O’Connor, MD (‘08) Spokane, WA Alejandro Flores, MD (‘11) Boston, MA George J Fuchs, III, MD (‘09) Little Rock, AR James Heubi, MD (‘10) Cincinnati, OH Nicola Jones, MD (‘10) Toronto, ON Karen Murray, MD (‘11) Seattle, WA David A. Piccoli, MD (‘08) Philadelphia, PA Advocacy Committee John Udall, MD (‘11) Charleston, WV Randy Fenninger Washington, DC Warren Bishop, MD (’09) Iowa City, IA Steven J Czinn, MD (‘09) Baltimore, MD Maria M Oliva-Hemker, MD (‘10) Baltimore, MD Steven M Schwarz, MD (‘10) Brooklyn, NY Robert H Squires, Jr MD (‘11) Pittsburgh, PA Harland S Winter, MD (‘11) Boston, MA Rina Sanghavi, MD (‘11) Dallas, TX Ronald J Sokol, MD (‘11) Denver, CO Aliza Solomon, DO (‘08)** New York, NY Rebecca Cherry, MD (‘09)** Los Angeles, CA B UK Li, MD (08*) Milwaukee, WI Award Committee B UK Li, MD (‘08) Milwaukee, WI Melvin B Heyman, MD, MPH San Francisco, CA Emanuel Lebenthal, MD (‘08) Jerusalem, Israel Susan Henning, MD (’08) Chapel Hill, NC Joel Lavine, MD (‘08) San Diego, CA Michael Nowicki, MD (‘08) Jackson, MS

Clinical Care & Quality Committee Steven M Schwarz, MD (‘09) Brooklyn, NY Roxanne M Hecht, MD (‘08) Phoenix, AZ Jay Hochman, MD (‘09) Atlanta, GA Barbara Kaplan, MD (‘09) Cleveland, OH Colston McEvoy, MD (‘09) Greenville, SC Mihaela Ringheanu, MD (‘09) Harlingen, TX Pamela Brown, MD (‘10) Ann Arbor, MI Jyoti Ramakrishna, MD (‘10) Worcester, MA Anna Furr, MD (‘11) Portland, ME Esther Israel, MD (‘11) Boston, MA Harpreet Pall, MD (‘11) Boston, MA Joel R Rosh, MD (‘11) Morristown, NJ Francine Samuels, MD (‘08)** New York, NY Jason Dranove, MD (‘09)** Indianapolis, IN Helene Bacha, RN Montreal, PQ Karen Murray (‘11)* Seattle, WA Endoscopy & Procedures Committee Jenifer R Lightdale, MD (‘09) Boston, AM Fadi G Haddad, MD (’08) Oakland, CA Khalid Khan, MD (‘08) Minneapolis, MN Elizabeth Mannick, MD (’08) Kahului, HI Louis L. Mizell, MD (‘08) Salt Lake City, UT Bradley Barth, MD (‘09) Dallas, TX Mark J Integlia, MD (‘09) Portland, ME Marsha Kay, MD (‘09) Cleveland, OH R Bhanu Pillai, MD (‘10) Charleston, SC Brian Riedel, MD (‘10) Nashville, TN Douglas Fishman, MD (’11) Houston, TX Michael Nowicki, MD (’11) Jackson, MS Murali Jatla, MD (‘08)** Philadelphia, PA Catharine Walsh, MD (‘09)** Toronto, ON Judith O'Connor, MD,MS (‘08)* Spokane, WA Karen Murray (‘11)* Seattle, WA Ethics Committee Kathleen J Motil, MD PhD (‘09) Houston, TX Philip Rosenthal, MD (‘08) San Francisco, CA Adam G Mezoff, MD (‘09) Dayton, OH Ellen Blank, MD (‘10) Milwaukee, WI J Decker Butzner, MD (‘10) Calgary, AB TS Gunasekaran, MD (‘10) Park Ridge, IL Herbert Brill, MD (’11) Hamilton, ON Daniel Kamin, MD (’11) Boston, MA Jeffrey Morganstern, MD (’11) New York, NY Joshua Noe, MD (‘08)** Indianapolis, IN Megan Butler, MD (‘09)** Miami, FL Mary-Alice Tully, RN, PNP (‘08) Boston, MA Ivor D Hill, MB, ChB, MD (‘08)* Winston-Salem, NC David Gremse, MD (‘11)* Las Vegas, NV

17

Fellows Committee Karen Francolla, MD (‘08) Milwaukee, WI Rebecca Cherry, MD (‘09) ♦ Milwaukee, WI Julia Anderson, MD (‘08) Nashville, TN Keith Breglio, MD (‘08) New York, NY Brynie Slome Collins, MD (‘08) Los Angeles, CA Laurie Conklin, MD (‘08) Baltimore, MD Jason Ellison, MD (‘08) Iowa City, IA Benjamin Enav, MD (‘08) Los Angeles, CA Mary Abigail Garcia, MD (‘08) San Diego, CA Matthew Goldman, MD (‘08) Washington, DC Amber H Langshaw, MD (‘08) Miami, FL Humaira Hashmi, MD (‘08) Buffalo, NY Farrah Lazare, MD (‘08) Brooklyn, NY Priya Venkataraman, MD (‘08) Houston, TX Ryan W Himes, MD (‘09) Houston, TX Jennifer McCullough, MD (‘09) Kansas City, MO Nadia Ovchinsky, MD (‘09) New York, NY Michael Pickens, DO (‘09) San Francisco, CA Melanie Rhue, MD (‘09) Cincinnati, OH Samantha Woodruff, MD (‘09) Denver, CO Jorge A Chavez Saenz, MD (’10) Mexico City, MX Sharon D'Mello, MD (’10) Cincinnati, OH Jose Garza, MD (’10) Cincinnati, OH Ying Lu, MD (’10) Boston, MA Michelle Sicard, MD (’10) Baltimore, MD Christine E Waasdorp, MD (’10) Aurora, CO B UK Li, MD (‘08)* Milwaukee, WI Kathleen Schwarz, MD (’10)* Baltimore Md Finance Committee Ivor D Hill, MB, ChB, MD (‘08) Winston-Salem, NC David Gremse, MD (‘10) ♦ Las Vegas, NV Chris J Dickinson, MD (‘08) Ann Arbor, MI Anne M Griffiths, MD (‘08) Toronto, ON Philip M Sherman, MD (‘08) Toronto, ON Menno Verhave, MD (‘09) Boston, MA Deborah K Freese, MD (‘09) Rochester, MN Philip Rosenthal, MD (‘09) San Francisco, CA John Barnard, MD (’10) Columbus, OH Janet Harnsberger, MD (’11) Salt Lake City, UT Mitchell D Shub, MD (‘11) Phoenix, AZ Hepatology Committee Barbara Anne Haber, MD (‘09) Philadelphia, PA Susan M Gilmour, MD (‘08) Edmonton, AB Harpreet Pall, MD (‘08) Boston, MA Frederick Watanabe, MD (‘08) Los Angeles, CA Kathleen M Loomes, MD (‘09) Philadelphia, PA Valerie McLin, MD (‘09) Houston, TX Pramod K. Mistry, MD (‘09) New Haven, CT Adam Davis, MD (‘10) San Francisco, CA Karan Emerick, MD (‘10) Hartford, CT Nitika A Gupta, MD (‘10) Atlanta, GA Simon Ling, MD (‘10) Toronto, ON Sabina Ali, MD (‘11) Oakland, CA Rima Fawaz, MD (‘11) Boston, MA Lynette Gillis, MD (‘11) Nashville, TN Sylvie Lebel, MD (‘11) Los Angeles, CA Cara Mack, MD (‘11) Aurora, CO

Jason Yap, MD (‘08)** Toronto, ON Orlee Guttman, MD (‘09)** Toronto, ON James E Heubi, MD (‘10)* Cincinnati, OH IBD Committee Athos Bousvaros, MD (‘09) Boston, MA Jeffrey Critch, MD (‘08) St John's, NF Lee A Denson, MD (‘08) Cincinnati, OH Pushpa Sathya, MD, FRCPC (‘09) Winnipeg, MB Michael C Stephens, MD (‘09) Milwaukee, WI Gitit Tomer, MD (‘09) Cincinnati, OH Mary Zachos, MD (‘09) Toronto, ON Richard Colletti, MD (‘10) Burlington, VT Lynn Duffy, MD (‘10) Rockville, MD William Faubion, MD (‘10) Rochester, MN Mark Integlia, MD (‘10) Portland, ME Michael Kappelman, MD (‘10) Chapel Hill, NC Maria Oliva-Hemker, MD (‘10) Baltimore, MD Helen Pappa, MD (‘10) Boston, MA Paul Rufo, MD (‘10) Boston, MA Harohalli Shashidhar, MD (‘10) Lexington, KY Robbyn Sockolow, MD (‘10) New York, NY Jennifer Strople, MD (‘10) Chicago, IL Francisco Sylvester, MD (‘10) Hartford, CT John Udall, Jr, MD (‘10) Charleston, WV Cheryl Blank, MD (’11) Portland, ME Ghassan Wahbeh, MD (’11) Seattle, WA Wallace V Crandall, MD (‘11) Columbus, OH Janis Arnold, LICSW Boston, MA Laura T Durant Massapequa, NY Jennifer C. Jaff, Esq. Farmington, CT Marjorie Merrick New York,NY Deborah Whitehurst, MS, ARNP Lexington, KY Jyoti Sinha, MD (‘08)** New York, NY Jaime Liou Wolfe, MD (‘09)** Baltimore, MD Estella M Alonso, MD (‘09)* Chicago, IL

International Committee Ruben E Quiros, MD (‘09) Houston, TX Helen A John-Kelly, MD (‘08) Flushing, NY José Armando Madrazo, MD (‘08) Mexico City, MX Libia C Moy, MD (‘08) New Hyde Park, NY Dinesh S Pashankar, MD (‘08) New Haven, CT Ana Maria G Sant'Anna, MD (‘08) Hamilton, ON Neil T Tucker, MD (‘08) Ft Lauderdale, FL Regino P Gonzalez-Peralta, MD(‘09) Gainesville, FL Shehzad A Saeed, MD (‘09) Birmingham, AL Ricardo Caicedo, MD (‘10) Winston-Salem, NC Armando Madrazo, MD (‘11) Mexico City, MX Christine Targa-Ferreira, MD (‘11) Port Alegre, Brazil Carlos A. Velasco, MD (‘11) Cali, Columbia Qian Yuan, MD (‘11) Boston, MA Narayanan Venkatasubramani, MD (‘08)** Milwaukee, WI Leonardo R Hormaza, MD (‘09)** Chicago, IL Nicola Jones, MD (10)* Toronto, ON

18

Neurogastroenterology & Motility Committee Samuel Nurko, MD (‘10) Boston, MA William Berquist, MD (’10) Palo Alto, CA Christophe Faure, MD (’10) Montreal, PQ Jeffrey Hyams, MD (’10) Hartford, CT Miguel Saps, MD (’10) Chicago, IL Gisela Chelimsky, MD (’11) Cleveland, OH Bruno Chumpitazi, MD (’11) Houston, TX Joseph Croffie, MD (’11) Indianapolis, IN Carlo Di Lorenzo, MD (’11) Columbus, OH Dominque Levesque, MD (’11) Montreal, PQ Manu Sood, MD (’11) Milwaukee, WI Nader Youssef, MD (’11) Morristown, NJ Alejandro Flores, MD (‘11)* Boston, MA Nutrition Committee Robert J Shulman, MD (‘08) Houston, TX Maria R Mascarenhas, MD (‘10) ♦ Philadelphia, PA Maria I Clavell, MD (‘08) Pittsburgh, PA Mark Corkins, MD (‘08) Indianapolis, IN Ann O Scheimann, MD (‘08) Baltimore, MD Stephanie Abrams, MD (‘09) Houston, TX Solange H Roussant, MD (‘09) Naucalpan, MX Susanna Huh, MD (‘09) Boston, MA Linda Muir, MD (‘09) Spokane, WA John F Thompson, MD (‘09) Miami, FL Dennis Black, MD (‘10) Memphis, TN J Andres Martinez, MD (‘10) Nashville, TN David Suskind, MD (‘10) Seattle, WA Christine Carter-Kent, MD (’11) Cleveland, OH Anupama Chawla, MD (’11) New York, NY Conrad Cole, MD (’11) Atlanta, GA Ahmed Dahshan, MD (’11) Tulsa, OK Praveen Goday, MD (’11) Milwaukee, WI Janaina Nogueira, MD (‘08)** Birmingham, AL Meghana Sathe, MD (‘09)** Dallas, TX Nicola Jones, MD (‘10)* Hamilton, ON President’s Advisory Committee John A Barnard, MD (‘08) Columbus, OH B Li, MD (‘10) ♦ Milwaukee, WI Mitchell B Cohen, MD Cincinnati, OH Richard B Colletti, MD Burlington, VT Peter R Durie, MD Toronto, ON William J Klish, MD Houston, TX Jay A Perman, MD Lexington, KY Philip M Sherman, MD, FRCPC Toronto, ON Ronald J Sokol, MD Denver, CO Frederick J Suchy, MD New York, NY Jon A Vanderhoof, MD Omaha, NE Harland S Winter, MD Boston, MA Professional Development Committee Karen F Murray, MD (‘08) Seattle, WA Mitchell Shub, MD (‘10) ♦ Phoenix, AZ Yoram Elitsur, MD (‘08) Huntington, WV Issam El-Halabi, MD (‘09) Tulsa, OK Benjamin Gold, MD (‘09) Atlanta, GA Chris Dickinson, MD (‘10) Ann Arbor, MI

Dedrick Moulton, MD (‘10) Nashville, TN Samra Blanchard, MD (’11) Baltimore, MD Jacqueline Fridge, MD (’11) Portland, OR Binita Kamath, MD (’11) Philadelphia, PA Bess Schoen, MD (’11) Atlanta, GA John D Feerick, Jr, MD (‘08)** Valhalla, NY Ajay Kumar Jain, MD (‘09)** Houston, TX Estella M Alonso, MD (‘09)* Chicago, IL Professional Education Committee Laurie Fishman, MD (‘08) Boston, MA John Pohl, MD (‘10) ♦ Temple, TX Sandeep Gupta (‘10) Indianapolis, IN Kevin J Kelly, MD (‘08) Willow Grove, PA Miriam B Vos, MD, MSPH (‘08) Atlanta, GA Mark Feist, MD (‘09) Indianapolis, IN Leo A Heitlinger, MD (‘09) Bethlehem, PA Michelle Pietzak, MD (‘09) Los Angeles, CA Kathy D Chen, MD (‘10) Philadelphia, PA Eyad Hanna, MD (‘10) Iowa City, IA Valeria Cohran, MD (‘11) Chicago, IL Daniel Gelfond, MD (‘11) Baltimore, MD Rose Graham-Maar, MD (‘11) Philadelphia, PA Melanie K Greifer, MD (‘11) New Hyde Park, NY Judith O’Connor, MD (‘11) Little Rock, AR Folashade Jose, MD (‘09)** San Francisco, CA Rita Walia, MD (’10)** Cleveland, OH George J Fuchs III, MD (‘09)* Little Rock, AR Public Education Committee Adelina McDuffie, RN (‘08) Norfolk, VA Philip Rogers, MD (‘09) Washington, DC Allan J Rosenberg, MD (07) New Orleans, LA Judy B Splawski, MD (07) Cleveland, OH Dana Dobrescu Ursea, MD (‘08) Phoenix, AZ Toba Weinstein, MD (‘08) New Hyde Park, NY Sari Acra, MD (‘09) Nashville, TN Carol Durno, MD (‘09) Toronto, ON Christopher Branner, MD (‘10) Charlotte, NC Mary P Francisco, MD (‘10) Kingsport, TN Suzanne Nelson, MD (‘10) Glenview, IL April Ulmer, MD (07)** Cheektowaga, NY Christine Carter-Kent, MD (‘08)** Cleveland, OH Ashish DebRoy, MD (‘09)** Iowa City, IA Lillian Sablan, RN (‘08) Milwaukee, WI Karen M Sherry, RN (‘08) Milwaukee, WI Judith O'Connor, MD,MS (‘08)* Spokane, WA Alejandro Flores, MD (‘11) Boston, MA Publications Committee Philip M Sherman, MD (‘08) Toronto, ON John A Barnard, MD (‘10) ♦ Columbus, OH Wayne I Lencer, MD (‘08) Boston, MA Ronald J Sokol, MD (‘09) Denver, CO Martín G Martín, MD (‘09) Los Angeles, CA Neil LeLeiko, MD (‘10) Providence, RI B Li, MD (‘10) Milwaukee, WI Judith M Sondheimer, MD (‘11) Denver, CO Eric Sibley, MD, PhD Palo Alto, CA

19

Research Committee D Brent Polk, MD (‘08) Nashville, TN David A Rudnick, MD PhD (‘10) ♦ St Louis, MO Glenn R Gourley, MD (‘08) Minneapolis, MN Stephen L Guthery, MD (‘08) Salt Lake City, UT Stephen James, MD, PhD (‘08) Bethesda, MD Cara L Mack, MD (‘08) Denver, CO Anne A Wolf, MD (‘08) Boston, MA Alan N Mayer, MD PhD (‘09) Milwaukee, WI Elyanne Ratcliffe, MD (‘09) New York, NY Jeffrey Rudolph, MD (‘09) Cincinnati, OH Edwin deZoeten, MD (‘10) Philadelphia, PA Sohail Husain, MD (‘10) New Haven, CT Sonia Michail, MD (‘10) Dayton, OH Hayat Mousa, MD (‘10) Columbus, OH Jorge Bezerra, MD (’11) Cincinnati, OH Yoram Elitsur, MD (’11) Huntington, WV Glenn Furuta, MD (’11) Denver, CO Neera Gupta, MD (’11) San Francisco, CA Elizabeth H Yen, MD (‘08)** Boston, MA Richard Kellermayer, MD (‘09)** Houston, TX George J Fuchs III, MD (‘09)* Little Rock, AR

Training Committee Alan M Leichtner, MD (‘09) Boston, MA Janice L Barkey, MD (‘08) Ottawa, ON Kathleen Campbell, MD (‘08) Cincinnati, OH Martha Dirks, MD (‘08) Montréal, PQ Jacqueline Fridge, MD (‘08) Oakland, CA A Craig Hillemeier, MD (‘08) Hershey, PA Judith Podskalny, PhD (‘08) Bethesda, MD Craig A Friesen, MD (‘09) Kansas City, MO M James Lopez, MD, PhD (‘09) Ann Arbor, MI Marian D Pfefferkorn, MD (‘09) Indianapolis, IN Michael Narkewicz, MD (‘10) Denver, CO Thomas J Sferra, MD (‘10) Oklahoma City, OK Steven Erdman, MD (’11) Columbus, OH Gregory Kobak, MD (’11) Norfolk, VA Veronique Morinville, MD (’11) Montreal, PQ Dinesh Pashankar, MD (’11) New Haven, CT Diana Riera, MD (‘08)** Washington, DC Wael Sayej, MD (‘09)** Buffalo, NY David A Piccoli, MD (‘08)* Philadelphia, PA James E Heubi, MD (‘10)* Cincinnati, OH

Chairs are in bold

♦ Incoming Chair ** Indicates Fellow * Indicates Council Liaison

20

Thursday, November 13, 2008

Poster Session I * Poster of Distinction

Exhibit Hall 5:00 pm-7:00 pm

(Presenters at posters from 5:30pm – 6:30pm)

ESOPHAGUS/STOMACH *1 EXTRACELLULAR MAJOR BASIC PROTEIN IN EOSINOPHILIC ESOPHAGITIS AS

COMPARED TO REFLUX ESOPHAGITIS. Jennifer M. Colombo, Nancy Neilan, Jennifer V. Schurman, James F. Daniel, Stephanie L. Page, Jennifer L. McCullough, Craig Friesen. Children's Mercy Hospital, Kansas City, MO, USA.

2 PHARMACOKINETICS OF 2 DOSE LEVELS OF PANTOPRAZOLE GRANULES AND TABLETS IN CHILDREN 1 THROUGH 11 YEARS WITH ENDOSCOPICALLY PROVEN GERD. B. Tammara1, K. Adcock2, G. Kearns3, R. Ward4, J. Giblin5, C. Shaheen1, X. Meng1, M. Maguire1, Gail M. Comer1. 1Wyeth, Collegeville, PA, USA; 2University of Mississippi Medical Center, Jackson, MS, USA; 3Children’s Mercy Hospitals and Clinics & University of Missouri, Kansas City, MO, USA; 4University of Utah Primary Children’s Medical Center, Salt Lake City, UT, USA; 5Clinical Study Centers, LLC, Little Rock, AR, USA.

3 EFFICACY AND SAFETY OF PANTOPRAZOLE GRANULES FOR SUSPENSION IN A TREATMENT-WITHDRAWAL STUDY IN INFANTS WITH SYMPTOMATIC GERD. Gail M. Comer1, Philip Kum-Nji2, Suleman H. Mahomedy3, Jaroslaw Kierkus4, Michelle Hinz1, Huihua Li1, Mary K. Maguire1, Harland Winter5. 1Wyeth Pharmaceuticals, Collegeville, PA, USA; 2Virginia Commonwealth University Children’s Pavilion, Richmond, VA, USA; 3Hiway Medical Center/Westville Medical Center, Westville Durban, South Africa; 4Children's Memorial Health Institute, Warsaw, Poland; 5MassGeneral Hospital for Children, Boston, MA, USA.

4 PHARMACOKINETICS OF 2 DOSE LEVELS OF PANTOPRAZOLE DELAYED-RELEASE GRANULES FOR ORAL SUSPENSION IN INFANTS AGED 1 THROUGH 11 MONTHS WITH PRESUMED DIAGNOSIS OF GERD. B. Tammara1, J. E. Sullivan2, M. A. Springer3, J. Kierkus4, N. Rath1, C. Fu1, X. Meng1, M. K. Maguire1, Gail M. Comer1. 1Wyeth Research, Collegeville, PA, USA; 2University of Louisville, Louisville, KY, USA; 3Louisiana State University Health Sciences Center, Shreveport, LA, USA; 4Children’s Memorial Health Institute, Warsaw, Poland.

5 PHARMACOKINETICS OF SINGLE AND MULTIPLE DOSES OF PANTOPRAZOLE IN ADOLESCENTS WITH GERD. B. Tammara1, R. Ward2, G. Kearns3, M. O’Gorman4, L. James5, M. Katz6, M. Maguire1, N. Rath1, X. Meng1, Gail M. Comer1. 1Wyeth Research, Collegeville, PA, USA; 2University of Utah, Salt Lake City, UT, USA; 3Children’s Mercy Hospitals and Clinics & University of Missouri, Kansas City, KS, USA; 4University of Utah Health Sciences Center, Salt Lake City, UT, USA; 5Arkansas Children’s Hospital Research Institute & University of Arkansas for Medical Sciences, Little Rock, AR, USA; 6Children’s Hospital of Orange County, Orange, CA, USA.

6 EOSINOPHILIC GASTRITIS IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS: DOES IT MATTER? Rana Ammoury1, Marc Rosenman2, Donita Roettcher1, Sandeep Gupta1. 1Pediatric Gastroenterology, Riley Hospital for Children, Indianapolis, IN, USA; 2Pediatrics, Riley Hospital for Children, Indianapolis, IN, USA.

21

7 INCREASED PREVALENCE OF GASTROESOPHAGEAL REFLUX DISEASE (GERD) AND

ITS COMPLICATIONS IN HOSPITALIZED U.S. CHILDREN. Tejas R. Mehta1, Troy Gibbons2, Seton McRae3, Traci Leong1, Jana Stockwell4, Rachel Kreh1, Benjamin Gold1. 1Div of Pediatric Gastroenterology, Emory Univ, Atlanta, GA, USA; 2Div of Pediatric Gastroenterology, Univ of Arkansas, Little Rock, AR, USA; 3Children’s Healthcare of Atlanta, Atlanta, GA, USA; 4Div of Pediatric Critical Care Medicine, Emory Univ, Atlanta, GA, USA.

8 SIGNIFICANCE OF IGG RAST TESTING IN PATIENTS WITH EOSINOPHILIC ESOPHAGITIS. Shaista Safder, Reema Gullati, Judy Splawski, Gisela Chelimsky. Pediatric Gastroenterology, Case Medical Center-Rainbow Babies and Children Hospital, Cleveland, OH, USA.

9 ACID EXPOSURE, NOT NUMBER OF REFLUX EPISODES AS DETECTED BY pH-MII, PREDICTS THE PRESENCE OF ESOPHAGITIS. Rachel Rosen, Jessica Lewis, Kristen Hart, Kate Donovan, Samuel Nurko. Motility Center, Children's Hospital Boston, Boston, MA, USA.

10 INADEQUATE ACID BLOCKADE IS COMMON IN CHILDREN TAKING PROTON PUMP INHIBITORS: A STUDY USING pH-MII. Rachel Rosen, Jessica Lewis, Kristen Hart, Donovan Kate, Samuel Nurko. Motility Center, Children's Hospital Boston, Boston, MA, USA.

11 EFFECT OF INFLAMMATORY MEDIATORS OF ESOPHAGITIS ON ESOPHAGEAL EPITHELIAL CELL p27 EXPRESSION: AN EARLY MARKER OF METAPLASIA? Kim-Doan K. Nguyen1, Stacy W. Blain2, Frank Gress3, William R. Treem1. 1Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, SUNY Downstate Medical Center, Brooklyn, NY, USA; 2Pediatrics, Anatomy and Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY, USA; 3Medicine, Division of Gastroenterology, SUNY Downstate Medical Center, Brooklyn, NY, USA.

12 EFFECT OF PROPOFOL ON ACID REFLUX MEASURED WITH THE BRAVO PH MONITORING SYSTEM. Yevgeniya Gyrda, Jeffrey Morganstern, Grace Walker, Anupama Chawla. Pediatrics, Stony Brook University Hospital, Stony Brook, NY, USA.

*13 TREATMENT WITH HIGH DOSE PROTON PUMP INHIBITORS DISTINGUISHES SEVERE ESOPHAGITIS FROM EOSINOPHILIC ESOPHAGITIS. Wael N. Sayej1, Raza Patel1, Robert D. Baker1, Eduardo Tron2, Susan S. Baker1. 1Digestive Diseases and Nutrition Center, Women & Children's Hospital of Buffalo, Buffalo, NY, USA; 2Pediatric Gastroenterology, Janet Weis Children’s Hospital, Danville, PA, USA.

*14 ESOPHAGEAL PH MONITORING WITH THE BRAVO™CAPSULE: EXPERIENCE IN A LARGE NUMBER OF CHILDREN FROM A SINGLE INSTITUTION. Joseph M. Croffie, Miriam Davis, Debbie S. Horn. Pediatrics, Indiana University, Indianapolis, IN, USA.

INTESTINE/COLON/IBD *15 CHILDREN WITH FAMILIAL ADENOMATOUS POLYPOSIS (FAP) AND EARLY

COLECTOMY: PSYCHOLOGICAL, QUALITY OF LIFE AND POUCH OUTCOME. C. Durno1,2, K. Butler2, T. Berk2, N. Aglingary2, M. Esplen2. 1GI & Nut, Hospital for Sick Children, Toronto, ON, Canada; 2Mt Sinai Hosp, Toronto, ON, Canada.

16 DEFINING GERMLINE BIALLELIC MISMATCH REPAIR MUTATIONS AS A NEW CAUSE OF GASTROINTESTINAL CANCER IN CHILDREN. C. Durno1,2, P. Sherman1, S. Holter2, S. Gallinger2. 1Hosp for Sick Children, Toronto, ON, Canada; 2Mt Sinai Hosp, Toronto, ON, Canada.

22

*17 WIRELESS CAPSULE ENDOSCOPY (CE): ARE THE BENEFITS WORTH THE RISKS? M. K. Jensen, Mehul Sheth, Richard Noel, Neelesh Tipnis. Pediatric Gastroenterology, Medical College of Wisconsin, Milwaukee, WI, USA.

18 CAN A WIRELESS ENDOSCOPY HIDE A DUODENAL MACROPOLYP IN PATIENT WITH PEUTZ JEGHERS SYNDROME? Barbara Bizzarri1, Fabiola Fornaroli1, Nicola de' Angelis2, Francesca Vincenzi1, Francesca Guatelli1, Gian Luigi de' Angelis1. 1Pediatric Gastroenterology, Parma, Italy; 2General Surgery, Parma, Italy.

19 CAPSULE ENDOSCOPY (CE) IN CHILDREN SUSPECTED OF SMALL BOWEL (SB) CROHN'S DISEASE (CD). M. Shah, M. Klooster, G. Yanni, S. Rajcevich, Y. Lopez. Pediatrics, Loma Linda University, Loma Linda, CA, USA.

20 SCREENING FOR CELIAC DISEASE (CD) IN PEDIATRIC TURNER SYNDROME (TS) IN LOS ANGELES. Leila Bozorgnia, Mitchell Geffner, Michelle Pietzak. Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

21 CORRELATION BETWEEN HLA-DQ TYPING, SMALL BOWEL AND GASTRIC MUCUSAL BIOPSIES IN THE DIAGNOSIS OF CELIAC DISEASE IN CHILDREN. Bisher Abdullah, Lisa Philichi, Corrine Maurins, Kathleen Rogacki, Robin Haws, Tonia Ruzyla. Pediatric Gastroenterology, Mary Bridge Children Hospital and Health Center, Tacoma, WA, USA.

22 DIAGNOSTIC PERFORMANCE OF DEAMIDATED GLIADIN ANTIBODIES IN PEDIATRIC CELIAC DISEASE. Fatma Sahin1, Maria Triantafyllopoulou2, E. Ntrivalas1, N. Bensen1, E. Fullmer1, Maurice O'Gorman1. 1Pathology and Laboratory Medicine, Children's Memorial Hospital, Chicago, IL, USA; 2Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Children's Memorial Hospital, Chicago, IL, USA.

23 QUALITY OF LIFE IN CHILDREN WITH CELIAC DISEASE. Muralidhar Jatla1,2, John F. Pohl1, Ritu Verma2, Tasha Burwinkle1, Caroline Kieserman-Shmokler2, Matthew Watts1. 1Pediatric Gastroenterology, The Children's Hospital at Scott & White, Temple, TX, USA; 2Divison of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

24 INCREASED RISK FOR BLOODSTREAM INFECTIONS AND DEATH AMONG SMALL SUBSETS OF PEDIATRIC INTESTINAL FAILURE PATIENTS. Emily N. Kevan, Samuel A. Kocoshis, Jeffrey A. Rudolph. Pediatric Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

25 EOSINOPHILIC INTESTINAL INFILTRATION AND NECROTIZING ENTEROCOLITIS IN PRETERM INFANTS. Azam Soroush1, Theodore Matulewicz2, Matthew Toohey1, Anna Petrova1. 1Pediatrics, Jersey Shore University Medical Center, Neptune, NJ, USA; 2pathology, Jersey Shore University Medical Center, Neptune, NJ, USA.

26 AN ASSOCIATION BETWEEN THE AMOUNT OF TIME SPENT PLAYING VIDEO GAMES AND FUNCTIONAL CONSTIPATION IN CHILDREN. Ismaeel Hashemi2, Muhammad A. Qureshi2, Kristen Kjerulf1. 1Penn State College of Medicine, Hershey, PA, USA; 2Penn State Children Hospital, Hershey, PA, USA.

23

27 IDENTIFICATION OF A NOVEL PICORNAVIRUS FROM A HUMAN PEDIATRIC DIARRHEA

SPECIMEN. Lori R. Holtz1, David Wang2, Carl D. Kirkwood3. 1Pediatrics, Washington University School of Medicine, Saint Louis, MO, USA; 2Molecular Microbiology and Pathology & Immunology, Washington University School of Medicine, Saint Louis, MO, USA; 3Enteric Virus Research Group, Murdoch Children’s Research Institute, Royal Children’s Hospital, Melbourne, VIC, Australia.

28 PICO-SALAX VERSUS POLY-ETHYLENE GLYCOL FOR BOWEL CLEANOUT BEFORE COLONOSCOPY IN CHILDREN-A RANDOMIZED CONTROLLED TRIAL. Dan Turner, E. I. Benchimol, H. Dunn, A. M. Griffiths, K. Frost, V. Scaini, J. Avolio, S. C. Ling. SickKids Hospital, Toronto, ON, Canada.

PANCREAS/CYSTIC FIBROSIS 29 PANCREATIC STENT USE DURING ERCP IN PEDIATRIC PATIENTS. Douglas S. Fishman1,

Mark A. Gilger1, Isaac Raijman2. 1Pediatric Gastroenterology, Texas Children's Hospital, Houston, TX, USA; 2Digestive Associates of Houston, Houston, TX, USA.

30 CYCLIC-AMP ACCELERATES CALCIUM WAVES IN PANCREATIC ACINAR CELLS VIA THE RYANODINE RECEPTOR. Ahsan U. Shah1, Wayne M. Grant1, Sahibzada U. Latif2, Alexander J. Park1, Zahir M. Mannan1, Sohail Z. Husain1. 1Pediatrics, Yale University, New Haven, CT, USA; 2Internal Medicine, Michigan State University, East Lansing, MI, USA.

31 PANCRELIPASE DELAYED-RELEASE CAPSULES (CREON®): EFFICACY AND SAFETY IN CHILDREN LESS THAN 7 YEARS OLD WITH PANCREATIC EXOCRINE INSUFFICIENCY DUE TO CYSTIC FIBROSIS. Suntje Sander-Struckmeier1, David Boyd2, Steven D. Caras2. 1Solvay Pharmaceuticals GmbH, Hannover, Germany; 2Solvay Pharmaceuticals, Inc., Marietta, GA, USA.

32 A PRE-POST RETROSPECTIVE STUDY OF GASTROSTOMY TUBE PLACEMENT IN CHILDREN WITH CYSTIC FIBROSIS. Chad Best, S. Schwarzenberg, J. Dunitz, J. Phillips, B. Holme, P. Gaillard. University of Minnesota, Minneapolis, MN, USA.

33 CLINICAL PRESENTATION AND MANAGEMENT OF PANCREATITIS IN CHILDREN: A 14-YEAR ANALYSIS. Alexander J. Park1, Latif U. Sahibzada2, Ahsan U. Shah1, Dinesh Pashankar1, Bhandari Vineet1, Sohail Z. Husain1. 1Pediatrics, Yale University, New Haven, CT, USA; 2Internal Medicine, Michigan State University, East Lansing, MI, USA.

34 BODY MASS INDEX (BMI) GREATER THAN 85TH PERCENTILE AND HISPANIC ETHNICITY ARE RISK FACTORS FOR ASPARAGINASE-INDUCED PANCREATITIS AND RELATED COMPLICATIONS. Emma M. Jones1, Terzah M. Horton1, Douglas S. Fishman2. 1Pediatric Hematology/Oncology, Texas Children's Hospital, Houston, TX, USA; 2Section of Pediatric Gastroenterology, Nutrition and Hepatology, Texas Children's Hospital, Houston, TX, USA.

35 EUR-1008 IMPROVES SIGNS AND SYMPTOMS OF MALABSORPTION IN YOUNG ADULT AND VERY YOUNG PATIENTS WITH EXOCRINE PANCREATIC INSUFFICIENCY (EPI) ASSOCIATED WITH CYSTIC FIBROSIS (CF). J. Heubi1, S. Boas2, K. Blake3, S. Nasr4, M. Woo5, K. Hardy6, R. Amaro-Galvez7, M. Latino8, C. Lee9. 1CCHMC, Cincinnati, OH, USA; 2Chicago CF Care, Glenview, IL, USA; 3Nemours, Jacksonville, FL, USA; 4U Mich, Ann Arbor, MI, USA; 5Children's H, Los Angeles, CA, USA; 6Children's H, Oakland, CA, USA; 7U Texas, Tyler, TX, USA; 8Eurand, Milan, Italy; 9Eurand, Vandalia, OH, USA.

24

Poster Session I - Clinical Vignettes

Exhibit Hall

5:00 pm-7:00 pm (Presenters at posters from 5:30pm – 6:30pm)

ESOPHAGUS/STOMACH

36 GASTRIC OUTLET OBSTRUCTION: AN UNUSUAL PRESENTATION OF EOSINOPHILIC GASTROENTERITIS IN ADOLESCENCE. Meghana N. Sathe, Michael Russo, John Andersen. Pediatric Gastroenterology, UTSW, Dallas, TX, USA.

37 CANDIDA ESOPHAGITIS AND PSEUDOMONAS COLITIS IN ASSOCIATION WITH HENOCH-SCHONLEIN PURPURA (HSP). Stephen Nanton1, Raed Sulaiman2, Philip Rosenthal3. 1Pediatric Gastroenterology, Avera Children's Hospital, Sioux Falls, SD, USA; 2Pathology, Avera McKennan Hospital, Sioux Falls, SD, USA; 3Pediatric Gastroenterology and Hepatology, University of California San Francisco Medical Center, San Francisco, CA, USA.

38 CONSERVATIVE MANAGEMENT IN A LARGE PENETRATING GASTRIC ULCER. Jaime L. Morrison1,2, Adam Mezoff1,2. 1Pediatrics, Wright State University School of Medicine, Dayton, OH, USA; 2Dayton Children's, Dayton, OH, USA.

39 ENDOSCOPIC PYLORIC BALLOON DILITATION FOR RECURRENT GOO FOLLOWING SUCCESSFUL PYLOROMYOTOMY FOR INFANTILE HYPERTROPIC PYLORIC STENOSIS. Jose Diaz-Miron3, Mary Brandt2, Bruno P. Chumpitazi1. 1Pediatrics, Texas Children's Hospital, Houston, TX, USA; 2Pediatric Surgery, Texas Children's Hospital, Houston, TX, USA; 3Baylor College of Medicine, Houston, TX, USA.

40 PROLONGED RETENTION OF ENDOSCOPICALLY PLACED HEMOCLIPS IN A PEDIATRIC PATIENT - A CASE REPORT. Matthew Wyneski, Orhan Atay, Marsha Kay, Lori Mahajan, Robert Wyllie, Vera Hupertz. Pediatric Gastroenterology, Cleveland Clinic Foundation, Cleveland, OH, USA.

41 POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER DIAGNOSED FOLLOWING UPPER ENDOSCOPY. Oren Koslowe, Eduardo Perelstein, Valerie Johnson, Debra Beneck, Robbyn Sockolow. New York Presbyterian Hospital- Weill Cornell Medical Center, New York, NY, USA.

42 GASTRIC DUPLICATION WITH ACUTE GASTROINTESTINAL HEMORRHAGE IN INFANCY: ENDOSCOPIC FINDINGS. M. Samer Ammar. Pediatric, GI Division, SIU School of Medicine, Springfield, IL, USA.

43 GASTROINTESTINAL SYMPTOMS OF COLLAGENOUS GASTRITIS TREATED WITH A GLUTEN-FREE DIET. Janice Heikenen1, C. J. Cold2, J. M. Resnick2. 1Pediatrics/Gastroenterology, Marshfield Clinic, Marshfield, WI, USA; 2Pathology, Marshfield Clinic, Marshfield, WI, USA.

44 GASTRIC ANTRAL VASCULAR ECTASIA (GAVE). Brent Keith, Paul Hyman, Raynorda Brown, Lolie Yu. Pediatric Gastroenterology, Children's Hospital/LSU, New Orleans, LA, USA.

25

45 IBUPROFEN AND CHRONIC PYLORIC STRICTURE. Edward J. Hoffenberg, Thomas Flass.

Pediatrics, U Colorado Denver and The Childrens Hospital, Denver, CO, USA.

46 UNUSUAL GASTRITIS IN AN ASYMPTOMATIC GIRL WITH SEVERE IRON DEFICIENCY ANEMIA. Claire Wilson1, Karen Thompson2. 1Pediatric Gastroenterology, Stanford University, Palo Alto, CA, USA; 2Pathology, Kapiolani Medical Center for Women and Children, Honolulu, HI, USA.

47 EOSINOPHILIC ESOPHAGITIS IN TWO CHILDREN WITH ESOPHAGEAL COIN INGESTION. Victor M. Pineiro-Carrero1, Vani Gopalareddy1, Will Ahrens2. 1Gastroenterology, Levine Children's Hospital, Charlotte, NC, USA; 2Pathology, Carolinas Medical Center, Charlotte, NC, USA.

MOTILITY/FUNCTIONAL GASTROINTESTINAL DISORDERS 48 RESPIRATORY FAILURE, COMPARTMENT SYNDROME, COLONIC PERFORATION AND

COLECTOMY: CONSTIPATION TO THE HIGHEST DEGREE. Desale Yacob, Jane P. Balint, Steven H. Erdman, Hayat M. Mousa, Carlo Di Lorenzo. Pediatric Gastroenterology, Nationwide Children's Hospital, Colomubus, OH, USA.

49 SYMPTOMATIC RELIEF OF IBS WITH RIFAXIMIN IN ADOLESCENCE. Shivinder Narwal, Graciela Wetzler. Pediatrics, Division of Pediatric Gastroenterology, Maimonides Medical Center, Brooklyn, NY, USA.

50 LYMPHOCYTIC COLITIS AS A MANIFESTATION OF FACTITIOUS DISORDER BY PROXY. Sylvia Arora2,1, Karla J. Au Yeung1, Arthur de Lorimier1, Carolyn Sullivan1. 1Pediatrics, Walter Reed Army Medical Center, Washington, DC, USA; 2Pediatrics Residency Program, National Capital Consortium, Bethesda, MD, USA.

51 DIVERSION COLITIS IN A 19 YEAR OLD PATIENT WITH MEGACYSTIS MICROCOLON INTESTINAL HYPOPERISTALSIS SYNDROME (MMIHS). Anita Talisetti, John Kerner. Pediatric Gastroenterology, Stanford University, Palo Alto, CA, USA.

PANCREAS/CYSTIC FIBROSIS 52 PANCREATITIS AND ORGANIC ACIDEMIA: SIGNAL PRESENTION AND SERIOUS

COMPLICATION. I. S. Fortgang, M. S. Petrescu, H. C. Andersson. Pediatrics, Tulane University School of Medicine, New Orleans, LA, USA.

53 HEMOSUCCUS PANCREATICUS IN A PEDIATRIC PATIENT WITH CHRONIC PANCREATITIS. David Troendle1, Meghana Sathe2, Jae-O Bae3, Jennifer Veltkamp4, Steve Megison3, Michael Russo2, John Andersen2. 1Pediatrics, UT Southwestern/Children's Medical Center Dallas, Dallas, TX, USA; 2Pediatric Gastroenterology, UT Southwestern, Dallas, TX, USA; 3Pediatric Surgery, UT Southwestern, Dallas, TX, USA; 4Pediatric Radiology, UT Southwestern, Dallas, TX, USA.

54 ACUTE PANCREATITIS ASSOCIATED WITH VARICELLA INFECTION IN AN IMMUNOCOMPETENT CHILD. Joon-Sung Kim, Ki-Won Oh, Ja-Hyeong Kim, Sang-Kyu Park, Jin-Young Jeong. Pediatrics, Ulsan University Hospital, Ulsan, South Korea.

55 LIFE THREATENING PRESENTATION OF ACUTE PANCREATITIS IN AN 11 YEAR OLD. Saad Ghafoor. 1Med/Peds, Creighton University, Omaha, NE, USA; 2UNMC, Omaha, NE, USA.

26


Plenary Session I Moderators: William Balistreri, MD and John Barnard, MD

Grand Ballroom AB 8:00am-10:00am

8:00am WELCOME

John Barnard, MD

8:05am CDHNF: A DECADE OF PROGRESS George Ferry, MD, Baylor College of Medicine and Past President, CDHNF

8:20am CDHNF INVESTIGATOR AWARDS/ CAREER VIGNETTES

David Rudnick MD, University of Washington, St. Louis Neera Gupta MD, University of California, San Francisco

8:50am 56 IDENTIFICATION OF SPECIFIC FOOD ANTIGEN(S) CAUSING EOSINOPHILIC ESOPHAGITIS IN CHILDREN TREATED WITH SIX FOOD ELIMINATION DIET. Ameesh Shah1, A. F. Kagalwalla2, H. Melin-Aldana1, S. Ritz1, T. S. Sentongo4, S. Nelson1, T. Hess1, B. U. Li3. 1Ped. Gastroenterology, Children's Memorial Hospital, Chicago, IL, USA; 2Ped. Gastroenterology, Univ. of Illinois Hospital, Chicago, IL, USA; 3Ped. Gastroenterology, Children's Hospital of Wisconsin, Milwaukee, WI, USA; 4Ped. Gastroenterology, Univ. of Chicago Hospital, Chicago, IL, USA.

9:05am 57 A DIET RICH IN POLYUNSATURATED FAT AND SUCROSE REPRODUCES KEY

FEATURES OF METABOLIC SYNDROME IN C57BL/6 MICE. Ryan W. Himes2,1, Sandy D. Cope-Yokoyama2,1, C. Wayne Smith2,1. 1Baylor College of Medicine, Houston, TX, USA; 2Texas Children's Hospital, Houston, TX, USA.

9:20 am BASIC SCIENCE YEAR-IN-REVIEW

Eric Sibley, MD, Stanford University, Editor, Journal of Pediatric Gastroenterology and Nutrition

9:50am Break

27


Plenary Session II Moderators: D. Brent Polk, MD and B Li, MD

Grand Ballroom AB 10:30am-12:00pm

10:30am MEETING UPDATE

B Li, MD, Program Chair

10:35am 58 FECAL MICROBIOTA IN INFANTS WITH AND WITHOUT NECROTIZING ENTEROCOLITIS. Uma Pisharody1, Michael J. Ferris1,2, Duna Penn1. 1Pediatrics, Louisiana State University Health Sciences Center, New Orleans, LA, USA; 2The Research Institute for Children, New Orleans, LA, USA.

10:50am 59 EPIGENETIC CHANGES IN MURINE COLONIC MUCOSA DURING POST-

WEANING DEVELOPMENT. Richard Kellermayer1, Sherin Mirza1, Nina Tatevian1, Lanlan Shen2, Robert A. Waterland1. 1Baylor College of Medicine, Houston, TX, USA; 2MD Anderson Cancer Center, Houston, TX, USA.

11:05am IMPROVING OUTCOMES VIA MAINTENANCE OF CERTIFICATION – FROM THE

AMERICAN BOARD OF PEDIATRIC GASTROENTEROLOGY SUBBOARD Chris Dickinson, MD, University of Michigan

11:20am CDHNF DRIVING THE AAP EQIPP MODULE ON GERD

Jenifer Lightdale, MD, Children’s Hospital Boston

11:35am CLINICAL SCIENCE YEAR IN-REVIEW William Balistreri, MD, Cincinnati Children’s Hospital Medical Center, Editor, Journal of Pediatrics

28


Poster Session II * Poster of Distinction

Exhibit Hall 12:00pm-2:00pm

(Presenters at posters from 12:30pm – 1:30pm)

HEPATOBILIARY/TRANSPLANT *60 OPHTHALMOLOGIC COMPLICATIONS IN CHILDREN WITH CHRONIC HEPATITIS C

TREATED WITH PEGYLATED INTERFERON. Michael Narkewicz1, Philip Rosenthal4, Kathleen B. Schwarz5, Arlene Drack2, Todd Margolis3, Michael X. Repka6. 1Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado Denver School of Medicine, Aurora, CO, USA; 2Department of Ophthalmology, University of Colorado Denver School of Medicine, Aurora, CO, USA; 3Department of Ophthalmology, University of California, San Francisco, San Francisco, CA, USA; 4Department of Pediatrics, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of California, San Francisco, San Francisco, CA, USA; 5Department of Pediatrics Section of Pediatric Gastroenterology, Hepatology and Nutrition, Johns Hopkins Medical Institutions, Baltimore, MD, USA; 6Department of Pediatrics and Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA.

*61 PROGRESSION IN PORTAL FIBROSIS DURING OMEGAVEN THERAPY IN TWO PATIENTS WITH INTESTINAL FAILURE. Jason Soden, Mark Lovell, Ronald J. Sokol. Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO, USA.

*62 PORCINE CYSTIC FIBROSIS MODEL: LIVER AND GALLBLADDER PHENOTYPE. Aliye Uc1, David K. Meyerholz2, David A. Stoltz3, Christopher S. Rogers3, Randall S. Prather4, Michael J. Welsh3,5. 1Pediatrics, University of Iowa, Iowa City, IA, USA; 2Pathology, University of Iowa, Iowa City, IA, USA; 3Internal Medicine, University of Iowa, Iowa City, IA, USA; 4Division of Animal Sciences, University of Missouri, Columbia, MO, USA; 5Howard Hughes Medical Institute, University of Iowa, Iowa City, IA, USA.

63 HEALTH RELATED QUALITY OF LIFE IN CHILDREN WITH NONALCOHOLIC FATTY LIVER DISEASE: BASELINE DATA FROM THE NASH CRN. Kristin David1, Jean Molleston2, Aynur Unalp-Arida3, Jeffrey B. Schwimmer1, Crn For the Nash4. 1University of California, San Diego, La Jolla, CA, USA; 2James Whitcomb Riley Hospital for Children, Indianapolis, IN, USA; 3Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; 4NASH, CRN, MD, USA.

64 SPECTRUM OF HISTOLOGICAL CHANGES IN PEDIATRIC NONALCOHOLIC FATTY LIVER DISEASE WITH NORMAL ALT. J. Molleston1, J. Schwimmer2, K. Murray3, O. Cummings1, A. Scheimann4, A. Unalp-Arida4, NASH Clinical Research Network For4. 1Indiana University, Indianapolis, IN, USA; 2University of California, San Diego, CA, USA; 3University of Washington, Seattle, WA, USA; 4Johns Hopkins, Baltimore, MD, USA.

65 OBSTRUCTIVE SLEEP APNEA IS NOT ASSOCIATED WITH NASH IN EXTREMELY OBESE ADOLESCENTS. Stavra Xanthakos1, Thomas Inge2, Maninder Kalra1. 1Pediatrics, Cincinnati Children's, Cincinnati, OH, USA; 2Surgery, Cincinnati Children's, Cincinnati, OH, USA.

29

66 GROWTH AFTER INFANT LIVER TRANSPLANTATION. Stacey Pollock, Nicola Jones, Simon

Ling, Annie Fecteau, Andreanne Benedir, Vicky L. Ng. SickKids Transplant Center, The Hospital for Sick Children, Toronto, ON, Canada.

67 CHRONIC HYPOXIA-INDUCED REGULATION OF ENZYMES OF GLUCOSE OXIDATIVE METABOLISM IN THE DEVELOPING LIVER ARE mTOR DEPENDENT. Girish C. Sharma1, Vikas Dukhande2, James C.K. Lai2, Reza Farahan1. 1Pediatrics Gastroenterology, New York Med College/ Westchester County Medical Center, Valhalla, NY, USA; 2Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy and Biomedical Research Institute, Idaho State University, Pocatello, ID, USA.

68 SYSTEMIC PROGRESSION OF TYPE IV GLYCOGEN STORAGE DISEASE AFTER LIVER TRANSPLANTATION. Valerie Marchand, Stephanie Williot, Andree Rasquin, Fernando Alvarez, Steven R. Martin. Gastroenterology, Hopital Ste-Justine, Montreal, QC, Canada.

69 SAFETY OF BLIND PERCUTANEOUS LIVER BIOPSY IN OBESE CHILDREN: A RETROSPECTIVE ANALYSIS. Jeremy Harwood1, Hua Liu1,2, Phyllis Bishop1,2, Michael Nowicki1,2. 1Pediatrics, University of MIssissippi Medical Center, Jackson, MS, USA; 2Division of Pediatric Gastroenterology, University of Mississippi Medical Center, Jackson, MS, USA.

70 SUDCA (URSODEOXYCHOLIC DISULFATE) - A UNIQUE UNIDIRECTIONAL BILE ACID FOR INTRAVENOUS USE IN LIVER TRANSPLANTATION AND TPN-ASSOCIATED CHOLESTASIS. Kenneth Setchell1, Nigel Heaton2, Ghalib Mukadam2, Melinda Yii2, Simon Phillips2, Trudi Phillips2, Hector Vilca-Melendez2. 1Pathology and Laboratory Investigation, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; 2Liver Transplant Unit, King's College Hospital, London, United Kingdom.

71 ABDOMINAL PAIN: DOES IT DISAPPEAR AFTER CHOLECYSTECTOMY? Manu R. Sood1, Neha Thapa1, Grzegorz Telega1, Paul Hyman2. 1Medical College of Wisconsin, Milwaukee, WI, USA; 2Louisiana State University and Children’s Hospital, New Orleans, LA, USA.

72 ACUTE LIVER FAILURE DUE TO PEGYLATED L-ASPARAGINASE: 4 CASE REPORTS FROM A SINGLE CENTER. Michele J. Alkalay, Naveen K. Mittal. Pediatric Gastroenterology, Hepatology and Nutrition, Children's Medical Center of Dallas, University of Texas at Southwestern, Dallas, TX, USA.

MOTILITY/FUNCTIONAL GASTROINTESTINAL DISORDERS 73 TREATMENT OF SOLITARY RECTAL ULCER SYNDROME (SRUS) WITH STAPLED

TRANSANAL RECTAL RESECTION (STARR). Bimal Agrawal, Frank Sinatra, Adrian Ortega, Para Chandrasoma, Michelle M. Pietzak. University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

74 THE PREVALENCE OF DYSPHAGIA IN INFANTILE GERD. Mark Fishbein1,4, Christina Branham3, Sibyl Cox3, Jennifer Pollock2, Laura Walbert2, Cheryl Fraker2. 1GI, Children's Memorial Hospital, Chicago, IL, USA; 2Dept of Rehabilitation, MMC, Springfield, IL, USA; 3Dept of Peds, SIU School of Medicine, Springfield, IL, USA; 4Dept of Peds, Northwestern University, Chicago, IL, USA.

30

75 NAUSEA REPORTS AS AN INDICATOR OF MORBIDITY. D. L. Christie1, Rona L. Levy2, S. L.

Langer2, W. E. Whitehead3, A. D. Feld4, O. S. Palsson3, M. M. Dupen2, S. A. Ballard2, M. M. Young1, M. M. Coffey1. 1Children's Hospital & Regional Medical Center, Seattle, WA, USA; 2University of Washington, Seattle, WA, USA; 3University of North Carolina, Chapel Hill, NC, USA; 4Group Health Cooperative, Seattle, WA, USA.

76 SEASONAL VARIATION IN RESPONSE TO TREATMENT IN CHILDREN WITH FUNCTIONAL ABDOMINAL PAIN. Miguel Saps, Nader Youssef, Adrian Miranda, Samuel Nurko, Amir Kagalwalla, Carlo Di Lorenzo. NO PAINS CONSORTIUM, Chicago, IL, USA.

77 ABDOMINAL PAIN, SCHOOL GRADES AND ABSENTEEISM. Miguel Saps1, Papa Adams1, Carlo Di Lorenzo2. 1Children's Memorial Hospital, Chicago, IL, USA; 2Nationwide Children's Hospital, Columbus, OH, USA.

78 A RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED, MULTI-CENTER TRIAL OF AMITRIPTYLINE IN CHILDREN WITH FUNCTIONAL ABDOMINAL PAIN. Miguel Saps1, Nader Youssef2, Adrian Miranda3, Samuel Nurko4, Jose Cocjin5, Carlo Di Lorenzo6. 1Children's Memorial Hospital, Chicago, IL, USA; 2Goryeb Children's Hospital, Morristown, NJ, USA; 3Medical College of Wisconsin, Milwaukee, WI, USA; 4Children's Hospital of Boston, Boston, MA, USA; 5Children's Mercy Hospital, Kansas City, MO, USA; 6Nationwide Children's Hospital, Columbus, OH, USA.

79 ANORECTAL MOTILITY ABNORMALITIES IN ENCOPRETIC CHILDREN WITH CHRONIC CONSTIPATION. Neeraj K. Raghunath, Mark S. Glassman, Michael S. Halata, Howard E. Bostwick, Stuart H. Berezin, Marvin S. Medow. Pediatrics, New York Medical College, Valhalla, NY, USA.

80 CHILD-REPORTED SOMATIC SYMPTOMS DIFFER IN CHILDREN WITH FUNCTIONAL ABDOMINAL PAIN AND IRRITABLE BOWEL SYNDROME IN PRIMARY VERSUS TERTIARY CARE SETTINGS. Bruno P. Chumpitazi, Mariella Lane, Danita Czyzewski, Robert Shulman. Pediatrics, Texas Children's Hospital, Houston, TX, USA.

81 FOOD ALLERGY TESTING IN CHILDREN/ADOLESCENTS WITH FUNCTIONAL DYSPEPSIA. Nancy Neilan, Craig Friesen, Paul Dowling, Debra Taylor, Pam Ryan, Jennifer V. Schurman. Children's Mercy Hospital, Kansas City, MO, USA.

82 DIAGNOSTIC SUBTYPING IN PEDIATRIC FUNCTIONAL DYSPEPSIA: RELATIONSHIPS BETWEEN MUCOSAL INFLAMMATION, PSYCHOLOGICAL FUNCTIONING, AND CLINICAL SYMPTOMS. Jennifer V. Schurman1,2, Meenal Singh2, Vivekanand Singh3, Nancy Neilan2, Jennifer M. Columbo2, Craig A. Friesen2. 1Section of Dev & Beh Sciences, Children's Mercy Hospital, Kansas City, MO, USA; 2Section of Gastroenterology, Children's Mercy Hospital, Kansas City, MO, USA; 3Section of Pathology, Children's Mercy Hospital, Kansas City, MO, USA.

83 BIOFEEDBACK-ASSISTED RELAXATION TRAINING AS AN ADJUNCT TO MEDICATION IN TREATMENT OF PEDIATRIC RECURRENT ABDOMINAL PAIN. Jennifer V. Schurman1,3, Yelena P. Wu2, Paula Grayson3, Jennifer M. Colombo3, Craig A. Friesen3. 1Section of Dev & Beh Sciences, Children's Mercy Hospital, Kansas City, MO, USA; 2Clinical Child Psychology Program, The University of Kansas, Lawrence, KS, USA; 3Section of Gastroenterology, Children's Mercy Hospital, Kansas City, MO, USA.

31

84 MONTELUKAST IN THE TREATMENT OF DUODENAL EOSINOPHILIA IN CHILDREN

WITH DYSPEPSIA: EFFECT ON EOSINOPHIL DENSITY AND ACTIVATION IN RELATION TO PHARMACOKINETICS . Craig Friesen, Nancy A. Neilan, Schurman V. Jennifer, Taylor L. Debra, Gregory L. Kearns, Susan M. Abdel-Rahman. Children's Mercy Hospital, Kansas City, MO, USA.

85 AUTONOMIC RESPONSE TO A MEAL IN CHILDREN WITH FUNCTIONAL DYSPEPSIA. Craig Friesen1, Zhiyue Lin2, Jennifer V. Schurman1, Debra L. Taylor1, Linda A. Andre1, Jennifer Colombo1, Richard W. McCallum2. 1Children's Mercy Hospital, Kansas City, MO, USA; 2University of Kansas Medical Center, Kansas City, KS, USA.

86 NON-PSYCHIATRIC CO-MORBIDITIES IN PEDIATRIC FUNCTIONAL GASTROINTESTINAL DISORDER (FGID): AN AREA IN NEED OF EXPLORATION. Shaista Safder, Thomas Chelimsky, Elizabeth Heller, Gisela Chelimsky. Case Medical Center, Cleveland, OH, USA.

87 POSTURAL TACHYCARDIA SYNDROME (POTS) AND FUNCTIONAL GASTROINTESTINAL DISORDERS (FGID): A ROLE FOR ALTERED ELECTRICAL ACTIVITY OF THE STOMACH? Shaista Safder, Thomas Chelimsky, Elizabeth Heller, MaryAnn O'Riordan, Gisela Chelimsky. Case Medical Center, Cleveland, OH, USA.

88 PROPHYLACTIC TREATMENT OF CYCLIC VOMITING SYNDROME WITH HYDROXYZINE HYDROCHLORIDE IN CHILDREN. Manoochehr Karjoo1, Mirza Beg1, Shannon Kesselring1, Afshin Karjoo1,2. 1Pediatrics, SUNY Upstate Medical University, Fayetteville, NY, USA; 2Massachusetts College of Pharmacy and Health Sciences, Worcester, MA, USA.

89 STUDY OF CEREBRAL REPRESENTATION OF THE RECTAL DISTENSION STIMULUS IN CHILDREN USING FUNCTIONAL MAGNETIC RESONANCE IMAGING. Manu R. Sood, Kern Mark, Rudolph Colin, Alan Silverman, Tarbell Sally, Reza Shaker. Medical College of Wisconsin, Milwaukee, WI, USA.

90 COMBINED PYLORIC BALLOON DILATATION AND BOTULINUM TOXIN A INJECTION FOR PEDIATRIC IDIOPATHIC GASTROPARESIS. Melanie Rhue, Ajay Kaul. Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

91 EFFECT OF AMOXICILIN-CLAVULANATE ON GASTROINTESTINAL MOTILITY. Sergio J. Fernandez, Ann Aspirot, Roberto Gomez, Beth Skaggs, Anna Cunningham, Hayat Mousa, Carlo Di Lorenzo. Nationwide Children's Hospital, Columbus, OH, USA.

NUTRITION/NUTRITION SUPPORT 92 WHAT DO PROVIDERS THINK ABOUT THE ETIOLOGIES OF CHILDHOOD FEEDING

PROBLEMS? Douglas Field, Keith Williams. Pediatrics, Penn State Hershey Children's Hospital, Hershey, PA, USA.

*93 PEDIATRICIANS’ DISCRIMINATION OF PERSONAL AND FAMILY WEIGHT STATUS AND WEIGHT SCREENING PRACTICES: RESULTS OF A SURVEY. Geraldline H. Kang, Susan Fernandez, Jeannie S. Huang. Pediatrics, UCSD, San Diego, CA, USA.

32

94 OVERWEIGHT CHILDREN AND PARENTAL PERCEPTIONS. Rona L. Levy1, Nancy E.

Sherwood2, Shelby L. Langer1, Robert Reid3, Sheri A. Ballard1. 1School of Social Work, University of Washington, Seattle, WA, USA; 2Epidemiology, University of Minnesota, Minneapolis, MN, USA; 3Preventive Care, Group Health, Seattle, WA, USA.

95 PATHOGENESIS OF HEPATIC LIPID DEPOSITION IN A MOUSE MODEL OF PARENTERAL NUTRITION ASSOCIATED LIVER DISEASE (PNALD) AND OMEGA-3 FATTY ACIDS. Farrah Lazare, Jahangir Iqbal, Xiayoue Pan, M. Mahmood Hussain, William R. Treem. Division of Pediatric Gastroenterology, SUNY Downstate, Brooklyn, NY, USA.

96 WHOLE BLOOD FREE CHOLINE AND CHOLINE METABOLITES IN INFANTS ON CHRONIC PARENTERAL NUTRITION THERAPY. Timothy Sentongo1, Praveen Kumar2, Betsy Hjelmgren2, Lisa Keys2, Kishore Iyer3, Alan Buchman4. 1Pediatrics, University of Chicago, Chicago, IL, USA; 2Pediatrics, Northwestern University, Chicago, IL, USA; 3Transplant Surgery, Mount Sinai Hospital, New York, NY, USA; 4Medicine, Northwestern University, Chicago, IL, USA.

97 MALTASE-GLUCOAMYLASE STARCH DIGESTING ACTIVITY (?-GLUCOGENESIS) REGULATES MOUSE PRANDIAL HEPATIC GLUCONEOGENESIS. Buford Nichols1, Roberto Quezada-Calvillo1,2, Maricela Diaz-Sotomayor1, Claudia Robayo-Torres1, Zihua Ao3, Bruce Hamaker3, Juan Marini1, Farook Jahoor1. 1Pediatrics, Baylor College of Medicine, Houston, TX, USA; 2Facultad de Ciencias Quimicas, Universidad Autonoma de San Luis Potosí, San Luis Potosí, Mexico; 3Food Sciences, Purdue University, West Lafayette, IN, USA.

98 REVERSAL OF SEVERE PARENTERAL NUTRITION INDUCED CHOLESTASIS WITH OMEGAVEN. Valerie Marchand1, Julie Lemale1, Lise Bouthillier1, Marjolain Pineault3, Alain Ouimet2. 1gastroenterology, Hopital Ste-Justine, Montreal, QC, Canada; 2Surgery, hopital Ste-Justine, Montreal, QC, Canada; 3Pharmacy, Hopital Ste-Justine, Montreal, QC, Canada.

99 EFFICACY OF CYPROHEPTADINE ON WEIGHT GAIN IN CHILDREN WITH FAILURE TO THRIVE. Jeffrey Blumenthal1,2, Juliet Krupa2, Benjamin Gold3. 1Children's Center for Digestive Healthcare, Atlanta, GA, USA; 2Children's Healthcare of Atlanta, Atlanta, GA, USA; 3Emory University School of Medicine, Atlanta, GA, USA.

100 EPICARDIAL FAT IS NOT AN INDEPENDENT PREDICTOR OF METABOLIC SYNDROME IN OVERWEIGHT CHILDREN. Grzegorz W. Telega1, Artur Mazur2, Mariusz Ostanski2, Ewa Malecka-Tendera3. 1Pediatric Gastroenterology and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA; 2Medical Faculty, University of Rzeszów, Rzeszow, Poland; 3Department of Pediatric Endocrinology and Diabetes, Medical University of Silesia, Rzeszow, Poland.

101 METABOLIC ALTERATIONS IN PARENTERAL NUTRITION ASSOCIATED LIVER DISEASE: POTENTIAL ROLES OF FARNESOID X RECEPTOR (FXR) AND FIBROBLAST GROWTH FACTOR 19 (FGF19). Ajay K. Jain1,2, Barbara Stoll2, Douglas G. Burrin2, David D. Moore2. 1Pediatrics, Texas Children’s Hospital, Houston, TX, USA; 2Baylor College of Medicine, Houston, TX, USA.

33

NOTES

34

Poster Session II - Clinical Vignettes

Exhibit Hall

12:00 pm-2:00 pm (Presenters at posters from 12:30pm – 1:30pm)

HEPATOBILIARY/TRANSPLANT

102 BILIARY ATRESIA ASSOCIATED WITH ALPHA-1-ANTITRYPSIN DEFICIENCY. Stephen Nanton1, Stephen Karl2, Philip Rosenthal3. 1Pediatric Gastroenterology, Avera Children's Hospital, Sioux Falls, SD, USA; 2Pediatric Surgery, Avera Children's Hospital, Sioux Falls, SD, USA; 3Pediatric Gastroenterology, University of California San Francisco Medical Center, San Francisco, CA, USA.

103 TELANGIECTATIC FOCAL NODULAR HYPERPLASIA OF THE LIVER IN A NEWBORN. Joon-Sung Kim1, Ki-Won Oh1, Chang-Woo Nam2, Seong-Hoon Choi3, Hye-Jeong Choi4, Sang-Kyu Park1. 1Pediatrics, Ulsan University Hospital, Ulsan, South Korea; 2Surgery, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea; 3Radiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea; 4Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea.

104 ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY IS AN EFFECTIVE ALTERNATIVE TO SURGERY FOR DIAGNOSIS AND MANAGEMENT OF BILIARY RHABDOMYOSARCOMA. Ryan W. Himes1, Isaac Raijman2, Milton J. Finegold1, Heidi V. Russell3, Douglas S. Fishman1. 1Baylor College of Medicine, Houston, TX, USA; 2Digestive Disease Associates of Houston, Houston, TX, USA; 3Texas Children's Cancer Center, Baylor College of Medicine, Houston, TX, USA.

105 HEPATIC MANIFESTATION OF NEONATAL GRAVE’S DISEASE. Osama F. Almadhoun, Teresa Penera-Rivera, Lauren Lipeski. Pediatric, St. Joseph's Children's Hospital, Paterson, NJ, USA.

106 RESPIRATORY SYNCTIAL VIRUS AND PEDIATRIC CHRONIC LIVER DISEASE (CLD): MEDICAL COLLEGE OF WI EXPERIENCe . Stacee Lerret, Julie Banda, Vincent Biank, Grzegorz Telega. Pediaric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA.

107 RESOLUTION OF HEPATOPULMONARY SYNDROME IN AN INFANT WITH ABERNETHY MALFORMATION TYPE 2 WITHOUT LIVER TRANSPLANTATION. Anup Patel, Daniel Sze, William Berquist. Stanford University, Palo Alto, CA, USA.

108 GEOGRAPHICAL NON-ALCOHOLIC FATTY LIVER DISEASE (NALFD) IN A CHILD. Rene D. Gomez-Esquivel1, Susan D. John2, Ruben E. Quiros-Tejeira1. 1Pediatrics - Division of GI, Hepatology & Nutrition, University of Texas, Houston, TX, USA; 2Department of Diagnostic and Interventional Imaging, University of Texas, Houston, TX, USA.

109 SIMULTANEOUS DIAGNOSIS OF AUTOIMMUNE HEPATITIS AND TYPE 1 DIABETES. Jennifer Garcia, Janine Sanchez, John Thompson, Erick Hernandez, Lesley Smith. Pediatrics, University of Miami, Miami, FL, USA.

35

110 REVERSAL OF PROTEIN-LOSING ENTEROPATHY AFTER LIVER TRANSPLANTATION IN A

CHILD WITH IDIOPATHIC FAMILIAL NEONATAL HEPATITIS. Naim Alkhouri1, Christine A. Carter-Kent1, Vera Hupertz1, Bijan Eghtesad2, John Fung2, Kadakkal Radhakrishnan1. 1Pediatric Gastroenterology, Cleveland Clinic, Cleveland, OH, USA; 2Transplant Center, Cleveland Clinic, Cleveland, OH, USA.

111 HEPATIC ABSCESSES, PYLEPHLEBITIS AND APPENDICEAL INFLAMMATION. Anup Patel, Judy Fuentebella, John Kerner. Stanford University, Palo Alto, CA, USA.

112 CONGENITAL INTRAHEPATIC ARTERIOPORTAL FISTULAS: INDICATION FOR LIVER TRANSPLANT. Julie Banda, Stacee Lerret, Vincent Biank, Grzegorz Telega. Pediatric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA.

113 ASCITES, HEPATITIS AND COAGULOPATHY: IS IT THE LIVER? Husam Mallah, Marilyn Brown, Koorosh Kooros, Natalie Sikka. Pediatric GI, University of Rochester, Rochester, NY, USA.

114 SUCCESSFUL STEROID TREATMENT FOR MULTIPLE HEPATIC HEMANGIOMAS WITH CONGESTIVE HEART FAILURE. David E. Brumbaugh, Shikha Sundaram. Pediatric Gastroenterology, University of Colorado, Aurora, CO, USA.

115 DYSTROPHINOPATHY: AN UNDERLYING CAUSE OF AMINOTRANSFERASE ELEVATION . Michael A. Russo. Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

NUTRITION/NUTRITION SUPPORT 116 EOSINOPHILIC GASTROENTEROPATHY IN A SIX YEAR OLD BOY: TREATMENT WITH AN

AMINO ACID BASED FORMULA. Amana Nasir, Oscar C. Estalilla, T. E. Huang, April Lawson, John N. Udall. Pediatrics, WVU Health Sciences Center, Charleston Division, Charleston, WV, USA.

117 PERCTUANEOUS ENDOSCOPIC GASTROSTOMY IN CHILDREN: A COMPARISON OF CLINICAL EXPERIENCE. Meghana N. Sathe, Sabina Ali, Michael Dougherty, Norberto Rodriguez-Baez. Pediatric Gastroenterology, UTSW, Dallas, TX, USA.

118 OMEGAVEN ASSOCIATED BURR CELL ANEMIA. Husam Mallah, Marilyn Brown. Pediatric GI, University of Rochester, Rochester, NY, USA.

119 CONGENITAL VITAMIN B12 DEFICIENCY ASSOCIATED WITH MATERNAL GASTRIC BYPASS SURGERY. Anupama Chawla, Mahmut Y. Çeliker. Pediatrics, Stony Brook University Hospital, Stony Brook, NY, USA.

36

120 MALTASE-GLUCOAMYLASE DEFICIENCY, SUGGESTED BY LOW BIOPSY MALTASE WITH

NORMAL SUCRASE ACTIVITY, IS CONFIRMED BY 13C-STARCH BREATH TEST. Maricela Diaz-Sotomayor1, Claudia Robayo-Torres1, Mark Gilger1, Antone Opekun2, Roberto Quezada-Calvillo1,3, Susan Baker4, Buford Nichols1. 1Pediatrics, Baylor College of Medicine, Houston, TX, USA; 2Medicine, Baylor College of Medicine, Houston, TX, USA; 3Facultidad de Ciencias Quimicas, Universidad Autonoma de San Luis Potosi, SLP, Mexico; 4Pediatrics, State University of New York, Buffalo, NY, USA.

121 REVERSAL OF CHOLESTASIS WITH LOW DOSE INTRAVENOUS OMEGA 6 INFUSION: CASE REPORT. Husam Mallah, Marilyn Brown. Pediatric Gastroenterology, University of Rochester, Rochester, NY, USA.

122 HEMOPHAGOCYTOTIC LYMPHOHISTIOCYTOSIS (HLH) IN TWO CHILDREN WITH CHRONIC INTESTINAL PSEUDO-OBSTRUCTION RECEIVING HOME PARENTERAL NUTRITION. Narayanan Venkatasubramani, Manu R. Sood, Colin D. Rudolph. Deparment of Pediatrics, Division of Pediatric Gastroenterology and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA.

37

NOTES

38


Concurrent Session I – Controversies in Treatment of Chronic Hepatitis Moderators: Jean Molleston MD and Latifa Yeung MD

Grand Ballroom A 2:00pm-3:30pm

Management of hepatitis B: Who, how and with what? Michael Narkewicz MD, The Children’s Hospital, Denver

Learning Objectives 1. Discuss the current indications for treatment of chronic hepatitis B 2. Describe the diagnostic approach to drug-resistant hepatitis B 3. Discuss current therapy (including multi-drug) for treatment of hepatitis B

Management of hepatitis C: What you can see and what you don’t! Kathleen Schwarz MD, Johns Hopkins University

Learning Objectives 1. Discuss the current indications for treatment of hepatitis C in children 2. Describe current treatment regimens for hepatitis C infection 3. Review the potential treatment side effects

Infectious hepatitis – non A-E: How the unalphabetized attack Karen Murray MD, Children’s Hospital and Regional Medical Center, Seattle

Learning Objectives 1. Discuss the epidemiology of non A-E viral hepatitis in neonates 2. Discuss the epidemiology of non A-E viral hepatitis in the adolescent 3. Describe the epidemiology of non A-E hepatitis in acute liver failure

39


Concurrent Session I – Autoimmunity and the Digestive Tract Moderators: Wallace Crandall, MD and James Lopez, MD

Grand Ballroom B 2:00pm-3:30pm

Autoimmunity: Pathophysiology Troy Torgerson MD, Children’s Regional Medical Center, Seattle

Learning Objectives 1. Provide the current diagnostic criteria for autoimmunity in general 2. Describe the genetic basis for autoimmune enteropathy and IPEX 3. Describe the current testing (including genetic) for various autoimmune enteropathies

Autoimmune enteropathy: Clinical presentation and treatment Harland Winter MD, Massachusetts General Hospital for Children

Learning Objectives 1. Review the clinical presentation of autoimmune enteropathies 2. Describe the utility of serological testing 3. Characterize the current treatment regimens for this disorder

Autoimmune hepatitis: Update Deborah Freese MD, Mayo Clinic

Learning Objectives 1. Discuss the incidence, pathophysiology, and disgnosis of type I and type II autoimmune

hepatitis and overlap syndromes 2. Review new therapeutic options for treatment in children. 3. Identify treatment options for recurrence post liver transplantation

40


Concurrent Session I – Research Interest Group – Eosinophils and Probiotics

Moderators: Glenn Gourley, MD and Sonia Michail, MD

Seabreeze Room 2:00pm-3:30pm

State of the Art Lecture - PROBIOTICS; FACTS, FICTION AND FUTURE

Bjent Björkstén, MD, PhD, Karolinska Institute, Stockholm, Sweden

NASPGHAN/CDHNF Young Investigator Award STUDIES ON THE ROLE OF MAST CELLS IN EOSINOPHILIC ESOPHAGITIS. Edda Fiebiger, MD Harvard University, Boston, MA.

State of the Art Lecture - BUGS, BILOBED NUCLEI AND BITES OF FOOD- WHAT

ARE THE RELATIONSHIPS BETWEEN BACTERIA, EOSINOPHILS AND FOOD ALLERGIC DISEASES? Glenn Furuta, MD, Children’s Hospital, Denver CO

Learning Objectives 1. Identify potential relationships between food allergic diseases, eosinophils and bacteria 2. Determine clinical implications of these relationships

124 EGD IN CHILDREN WITH ABDOMINAL PAIN. Kalpesh Thakkar1, Leon Chen1, Nina

Tatevian1, Adelina McDuffie2, Mark Gilger1. 1Baylor, Houston, TX, USA; 2CHKD, Norfolk, VA, USA.

NOTES

42


Concurrent Session II – NEW Clinical Updates Moderators: Ann Scheimann, MD and John Thompson, MD


Eosinophilic esophagitis (EE): TIGERS consensus 2007 Chris Liacouras, MD, Children’s Hospital of Philadelphia

Learning Objectives 1. Review the consensus re: histologic criteria for diagnosis of EE 2. Discuss the food-elimination diet and its practical aspect 3. Compare the efficacy of various steroid preparations (including treatment of relapses)

Celiac disease – What’s new? Ed Hoffenberg MD, The Children’s Hospital, Denver

Learning Objectives 1. Discuss a new celiac disease test: antibodies to deamidated gliadin peptide 2. Discuss what to do with the diabetic child with evidence of celiac disease 3. Review new food labeling laws

NAFLD: A supersized liver Miriam Vos, Emory University

Learning Objectives 1. Discuss histologic and radiographic diagnostic criteria 2. Review the treatment options (metformin, UDCA and vitamin E) 3. Identify the effect of bariatric surgery on prevention and/or reversal of NAFLD

43


Concurrent Session II – Advanced Endoscopic Techniques Moderators: Marsha Kay, MD and Petar Mamula, MD


Capsule endoscopy: State of the art in children Stan Cohen, Children’s Center for Digestive Healthcare, Atlanta

Learning Objectives 1. Review capsule endoscopy procedures and competency requirements 2. Describe the current indications for capsule endoscopy in children 3. Identify new types of capsule endoscopy and future pediatric uses

Endoscopic Botox in pediatrics: Not just for the 40+ crowd Samuel Nurko MD, Children’s Hospital Boston

Learning Objectives 1. Describe the mechanism, duration of action and technique of injection of botulinum toxin 2. Review the technique and results for cricopharyngeal achalasia, achalasia and pyloric

dysfunction 3. Review the technique and results for anal achalasia and Hirschsprung’s disease

Single and double-balloon enteroscopy: Are they ready for prime time? Bradley Barth, MD, Children’s Medical Center of Dallas

Learning Objectives 1. Discuss emerging techniques in enteroscopy 2. Review current clinical trials 3. Identify potential clinical indications in pediatrics and limitations of technique and

equipment

44


Concurrent Session II - Translational Issues in GI and Liver Disease Moderators: David Rudnick, MD and Binita Kamath, MD

Seabreeze Room 3:30 pm-5:00 pm

125 IDENTIFICATION OF A SIGNALING AXIS ALONG THE BILE DUCT REGULATED

BY MECHANOSENSITIVE ATP RELEASE. Kangmee Woo, Meghana Sathe, Charles Kresge, Amal Dutta, Andrew Feranchak. Pediatrics, University of Texas Southwestern, Dallas, TX, USA.

126 AUGMENTATION OF TGFβ1 SIGNALING BY THE ZINC FINGER PROTEIN, ZAS3. John Barnard1, Adam Yakovich1, Jianguo Du1, Bo Jiang1, Carl Allen2, Lai-Chu Wu3. 1Pediatrics, Nationwide Children's Hospital, Columbus, OH, USA; 2Pediatrics, Baylor College of Medicine, Houston, TX, USA; 3The Ohio State University, Columbus, OH, USA.

127 DYNAMIC LIVE-CELL IMAGING OF BILIARY EPITHELIAL CELLS: EVIDENCE OF AN ATP-ENRICHED VESICLE COMPARTMENT. Meghana N. Sathe1, Charles Kresge1, Andrew Feranchak1, Abhigit Budge2, Julie Venteer3, Yoshiyuki Ueno4, Gianfranco Alpini4. 1Pediatric Gastroenterology, UTSW, Dallas, TX, USA; 2Cell Biology, UTSW, Dallas, TX, USA; 3Medicine, Texas A&M, Temple, TX, USA; 4Division of Gastroenterology, Tohoku University, Sendai, Miyagi Prefecture, Japan.

NASPGHAN/CDHNF Young Investigator Award MOLECULAR REGULATION OF VISCERAL MESODERM DEVELOPMENT. Valerie McLin, MD Baylor College of Medicine, Houston, TX.

128 OSTEOPONTIN - NULL MICE ARE PROTECTED FROM CITROBACTER RODENTIUM-INDUCED COLONIC HYPERPLASIA. Eytan Wine1,2, Grace Shen-Tu1,2, Bo-Yee Ngan1, Jaro Sodek2, Ron Zohar2, Philip Sherman1,2. 1Research Institute, Hospital for Sick Children, Toronto, ON, Canada; 2University of Toronto, Toronto, ON, Canada.

129 NONALCOHOLIC FATTY LIVER DISEASE IS ASSOCIATED WITH HEPATIC AND SKELETAL MUSCLE INSULIN RESISTANCE IN OVERWEIGHT ADOLESCENTS. Sheela Deivanayagam1,2, B. Selma Mohammed2, Bernadette E. Vitola1,2, Gihan Naguib1,2, Tamir Keshen3, Erik Kirk2, Samuel Klein2. 1Pediatric Gastroenterology, Washington University, St. Louis, MO, USA; 2Geriatrics and Nutritional Science, Center for Human Nutrition, Washington University, St. Louis, MO, USA; 3Pediatric Surgery, Washington University, St. Louis, MO, USA.

45

NOTES

46


Poster Session III *Posters of Distinction

Exhibit Hall 7:00 am-9:00 am

(Presenters at posters from 7:30am – 8:30am)

INTESTINE/COLON/IBD *130 IMPACT OF IMMUNOSUPPRESSION ON SEROLOGIC RESPONSE TO INFLUENZA

VACCINE IN PEDIATRIC PATIENTS WITH INFLAMMATORY BOWEL DISEASE. Ying Lu1, Denise L. Jacobson2, Lori A. Ashworth1, Richard J. Grand1, Anthony L. Meyer3, Monica M. McNeal3, Sandra K. Burchett1, Matt C. Gregas1, Athos Bousvaros1. 1Children's Hospital Boston, Boston, MA, USA; 2Harvard School of Public Health, Boston, MA, USA; 3Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA.

*131 ENDOSCOPIC ULTRASOUND TO GUIDE MANAGEMENT OF PEDIATRIC PERIANAL CROHN’S DISEASE: A SINGLE-CENTER FIVE-YEAR EXPERIENCE. Michael J. Rosen, Dedrick E. Moulton, Tatsuki Koyama, Walter M. Morgan, Stephen E. Morrow, Alan J. Herline, Roberta L. Muldoon, Paul E. Wise, D. B. Polk, David A. Schwartz. Vanderbilt University Medical Center, Nashville, TN, USA.

132 BURDEN OF CHILDHOOD ONSET INFLAMMATORY BOWEL DISEASE (IBD) IN THE UNITED STATES (US): A LARGE POPULATION BASED STUDY DETERMINES THE INCIDENCE, PREVALENCE AND CUMULATIVE MEDICATION EXPOSURE. T. Adamiak1, D. Walkiewicz-Jedrzejczak2, D. Fish3, C. Brown4, J. Tung5, K. Khan6, W. Faubion5, R. Park3, J. Heikenen3, M. Yaffe7, M. Rivera-Bennett8, M. Weidkamp2, R. Arumugam9, M. Nugent1, J. Nebel1, P. Simpson1, Subra Kugathasan10. 1Med College of WI, Milwaukee, WI, USA; 2Univ of WI-Madison, Madison, WI, USA; 3Marshfield Clinic, Marshfield, WI, USA; 4Gastro Assoc, Wausau, WI, USA; 5Mayo Clinic, Rochester, MN, USA; 6Univ of MN, Minneapolis, MN, USA; 7Dean Clinic, Madison, WI, USA; 8GI Consult, Milwaukee, WI, USA; 9MN Gastro, Minneapolis, MN, USA; 10Emory Univ School of Med, Atlanta, GA, USA.

133 MEDICATION ADHERENCE AND BARRIERS TO ADHERENCE AMONG TEENS WITH INFLAMMATORY BOWEL DISEASE. Rachel N. Greenley1,3, Alyssa Doughty1, Subra Kugathasan2,4. 1Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA; 2Pediatrics, Emory University School of Medicine, Atlanta, GA, USA; 3Children's Hosptial of Wisconsin, Milwaukee, WI, USA; 4Emory Children's Center & Children's Health Care of Atlanta, Atlanta, GA, USA.

134 EVALUATION OF INTESTINAL FIBROSIS IN TNBS RAT MODEL OF CROHN’S DISEASE (CD) USING ULTRASOUND ELASTICITY IMAGING (UEI). Sujal Rangwalla, L. Johnson, J. Rubin, K. Kim, J. Congxian, P. Higgins. University of Michigan Health Systems, Ann Arbor, MI, USA.

135 THE VWF (VOTING WITH THEIR FEET) ENDPOINT IN ULCERATIVE COLITIS (UC) CLINICAL TRIALS REFLECTS CLINICAL PRACTICE OUTCOMES . Sujal Rangwalla, A. Waljee, P. Higgins. University of Michigan Health Systems, Ann Arbor, MI, USA.

47

136 CORRELATION OF INSULIN-LIKE GROWTH FACTOR 1 (IGF-1) LEVELS WITH

INFLAMMATORY MARKERS IN PEDIATRIC CROHN’S DISEASE. Neera Gupta1, Robert Lustig1, Eric Vittinghoff2, Michael Kohn2, Marge McCracken3, Melvin B. Heyman1. 1Pediatrics, University of California San Francisco, San Francisco, CA, USA; 2Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA; 3Pediatrics, Pediatric Gastroenterology Associates, San Jose, CA, USA.

137 EARLY AND LATER ONSET CROHN'S DISEASE ARE INDISTINGUISHABLE AT COMMON GENETIC RISK VARIANTS. Jonah Essers1, J. Lee1, NIDDK IBD Genetics Consortium, S. Kugathasan2, R. Grand1, M. Daly3. 1Children's Hospital, Boston, MA, USA; 2Medical College of Wisconsin, Milwaukee, WI, USA; 3The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

138 AGE AT CROHN’S DISEASE ONSET AND STRICTURE CHARACTERISTICS ON CT ENTEROGRAPHY PREDICT OUTCOMES. Jeremy Adler1, Darashana R. Punglia2, Jonathan R. Dillman3, Maneesh Dave2, Joel F. Platt3, Mahmoud M. Al-Hawary3, Ellen M. Zimmermann2,4. 1Pediatric Gastroenterology, University of Michigan, Ann Arbor, MI, USA; 2Internal Medicine, University of Michigan, Ann Arbor, MI, USA; 3Radiology, University of Michigan, Ann Arbor, MI, USA; 4Gastroenterology, University of Michigan, Ann Arbor, MI, USA.

139 SARGRAMOSTIM FOR THE TREATMENT OF PEDIATRIC CROHN’S DISEASE (CD): A PHASE 1-2 SAFETY AND PHARMACOKINETIC STUDY. Judith R. Kelsen1, Petar Mamula1, Baldassano Robert1, Harlan Winter2, Sona Grossova Garie2, Catherine Scholz Scholz2. 1GI, Children's Hospital of Philadelphia, Philadelphia, PA, USA; 2GI, Mass General, Boston, MA, USA.

140 ENDOSCOPY AFFECTS PATIENT MANAGEMENT IN PEDIATRIC INFLAMMATORY BOWEL DISEASE. Kalpesh Thakkar1, Chantal Lucia1, George Ferry1, Adelina McDuffie2, Kevin Watson2, Marc Tsou2, Mark Gilger1. 1Baylor, Houston, TX, USA; 2CHKD, Norfolk, VA, USA.

141 CLINICAL SIGNIFICANCE OF FOCAL ACTIVE COLITIS IN CHILDREN WITH CHRONIC GASTROINTESTINAL SYMPTOMS. Zakia Sultana, David Carpentieri, Gary Silber, Mitchell Shub, Dana I. Ursea. Phoenix Childrens Hospital, Phoenix, AZ, USA.

142 OUTCOMES AFTER ILEAL RESECTION IN PAEDIATRIC CROHN DISEASE: A 30 YEAR SINGLE CENTER EXPERIENCE. Thomas D. Walters1, J. Langer2, R. McLeod2, M. Silverberg1, A. M. Griffiths1. 1Div. GI and Nutrition, Hospital for Sick Children, Toronto, ON, Canada; 2Dept Surgery, U of Toronto, Toronto, ON, Canada.

143 PREDICTION OF INFLAMMATORY BOWEL DISEASE (IBD) USING SEROLOGIC TESTING: A RETROSPECTIVE ANALYSIS. Derren M. Barken, Matthew J. McGinniss, Robert M. Nakamura, Henry Pan. Prometheus Laboratories Inc, San Diego, CA, USA.

144 ANASTOMOTIC ULCERS (AU) IN SHORT BOWEL SYNDROME (SBS). R. Gill, S. Duong, J. Xu, K. Nguyen, F. Lazare, S. Schwarz, T. Marciano, Y. Rivas, M. Van Winckel, S. Shahzed, S. Sirlin, A. Solomon, M. Kruijsen, R. Russell, W. Treem. Pediatric Gastroenterology and the Anastomotic Ulcer Study Group, SUNY Downstate Medical Center, Brooklyn, NY, USA.

145 NITAZOXANIDE TO TREAT EXACERBATIONS OF PEDIATRIC INFLAMMATORY BOWEL DISEASE (IBD). Youhanna Al-Tawil, Clarisa Cuevas, Alexandra Eidelwein, Wendy Taylor, Molly Hansen. Children's Hospital Pediatric Gastroenterology, P.C., Knoxville, TN, USA.

48

146 FECAL LACTOFERRIN AS A MARKER FOR COW'S MILK PROTEIN INTOLERANCE IN

INFANTS. Ian Macumber, Jay Fong, Jyoti Ramakrishna. Pediatrics/Pediatric GI and Nutrition, UMass Medical School/UMMHC, Worcester, MA, USA.

147 CO MORBIDITIES ASSOCIATED WITH METHANE PRODUCTION ON BREATH TEST. Shaista Safder, Gisela Chelimsky. Case Medical Center, Cleveland, OH, USA.

148 FOLATE RECEPTOR AUTOANTIBODIES IN CHILDREN WITH GASTROINTESTINAL MANIFESTATIONS OF FOOD ALLERGIES OR CROHNS DISEASE. W. Treem1, F. Lazare1, K. Nguyen1, J. Xu1, R. Gill1, J. Sequeira2, E. Quadros2. 1Pediatrics, SUNY Downstate School of Medicine, Brooklyn, NY, USA; 2Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA.

149 ROLE OF SMALL BOWEL THROUGH (SBFT) RADIOGRAPHS IN DIAGNOSING INFLAMMATION OF THE TERMINAL ILEUM (TI) IN PEDIATRIC PATIENTS. Matthew Stenerson1, Melvin B. Heyman1, Eric Vittinghoff2, Grace Kim3, Neera Gupta1. 1Pediatrics, University of California San Francisco, San Francisco, CA, USA; 2Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA; 3Pathology, University of California San Francisco, San Francisco, CA, USA.

150 A CD-ROM FOR ADOLESCENTS WITH IBD. Lynelle M. Boamah, Scott Pentiuk, Susan Moyer. Gastroenterology, Hepatology, and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

151 RAPID INFLIXIMAB INFUSIONS IN PEDIATRIC IBD. Edward J. Hoffenberg1,2, Alyson R. Yeckes2. 1Pediatrics-GI, U Colorado Denver, Aurora, CO, USA; 2GI, The Children's Hospital, Aurora, CO, USA.

ESOPHAGUS/STOMACH 152 A NOVEL FOUR DRUG REGIMEN (NITAZOXANIDE, AZITHROMYCIN, CEFDINIR, AND A

PPI) FOR THE TREATMENT OF PEDIATRIC HELICOBACTER PYLORI (HP) INFECTIONS. Asuncion Ramos-Soriano. Laredo Medical Center, Laredo, TX, USA.

153 ANTIBIOTIC RESISTANCE OF HELICOBACTER PYLORI (H. PYLORI) STRAINS IN SOUTH TEXAS. Mihaela Ringheanu1,2, Myrna Stockton1. 1Valley Baptist Medical Center, Harlingen, TX, USA; 2University of Texas Health Science Center, San Antonio, TX, USA.

154 PERCUTANEOUS ENDOSCOPIC GASTROSTOMY IN CHILDREN. Barbara Bizzarri1, Fabiola Fornaroli1, Nicola de 'Angelis2, Francesca Vincenzi1, Laura Rizzuti1, Marcello Sommi1, Gian Luigi de' Angelis1. 1Pediatric Gastroenterology, Parma, Italy; 2General Surgery, Parma, Italy.

155 PYLORIC STENOSIS AND HEMATEMESIS IN INFANCY. John Pohl, Lisa Sullivan, Dean Kjar, David Easley. Pediatric Gastroenterology, Scott and White, Temple, TX, USA.

156 VARIABLE PRESENTATIONS OF HERPES SIMPLEX ESOPHAGITIS IN CHILDREN AND ADOLESCENTS . Rima Jibaly1,2, Walid Abu-hammour1,2, Jenny LaChance1,2. 1Pediatrics, Hurley hospital, Flint, MI, USA; 2PED, MSU, Lansing, MI, USA.

157 CROHN'S DISEASE OF THE PROXIMAL ESOPHAGUS IN AN ADOLESCENT. Kim-Doan K. Nguyen1, Richard Alexis2, Steven Schwarz1. 1Pediatrics, SUNY Downstate Medical Center, Brooklyn, NY, USA; 2Pathology, Long Island College Hospital, Brooklyn, NY, USA.

49

158 EFFECTIVENESS OF THE CONSENT PROCESS USED FOR OUTPATIENT ENDOSCOPY.

Nancy Neilan, Debra Taylor, Craig Friesen, Peggy Ward-Smith. Children's Mercy Hospital, Kansas City, MO, USA.

159 PROPOFOL IS A SAFE AND COST-EFFECTIVE SINGLE AGENT FOR MANAGEMENT OF ESOPHAGEAL FOREIGN BODY REMOVAL IN PEDIATRIC PATIENTS. M. Yuwono1, T. Hurt1, A. Paschall1, L. Eagle1, T. Rossi2. 1Mary Bridge Children's Hospital, Tacoma, WA, USA; 2Children's Hospital at Strong, University of Rochester, Rochester, NY, USA.

160 ESOPHAGEAL STENT USE IN 5 CHILDREN. Chad Best, Khalid Khan. University of Minnesota, Minneapolis, MN, USA.

161 THE USE OF UPPER GASTROINTESTINAL (GI) STUDIES IN PYLOROSPASM: TIME FOR A STANDARD. Joanna Quigley3, Vesna Kriss2, Harohadli Shashidar1. 1Pediatric Gastroenterology, University of Kentucky, Lexington, KY, USA; 2Radiology, University of Kentucky, Lexington, KY, USA; 3Pediatrics, University of Kentucky, Lexington, KY, USA.

CELLULAR/MOLECULAR BIOLOGY 162 QUANTITATIVE AND QUALITATIVE DETECTION OF STOOL MICROFLORA. Sonia

Michail1, Frank Abernathy1, Harshavaradhan Kenche2, Oleg Paliy2. 1Pediatric Gastroenterology and Nutrition, Wright State Boonshoft School of Medicine, Dayton, OH, USA; 2Biochemistry and Molecular Biology, Wright State University Boonshoft School of Medicine, Dayton, OH, USA.

163 EOSINOPHILS ENHANCE TISSUE REMODELING. Vincent A. Mukkada1,2, Zachary Robinson2, Joanna Grenawalt2, Samantha Woodruff1,2, Sophie Fillon1,2, Steven J. Ackerman3, Glenn T. Furuta1,2. 1Pediatric Gastroenterology, The Children's Hospital, Denver, CO, USA; 2University of Colorado, Denver, CO, USA; 3Biochemistry and Molecular Biology, University of Illinois at Chicago, Chicago, IL, USA.

164 ASSESSMENT OF DUODENAL EXTRACELLULAR MAJOR BASIC PROTEIN: REPRODUCIBILITY AND CORRELATION WITH ELECTRON MICROSCOPY. Jennifer M. Colombo, Nancy Neilan, Jennifer V. Schurman, James F. Daniel, Jennifer L. McCullough, Stephanie L. Page, Craig Friesen. Children's Mercy Hospital, Kansas City, MO, USA.

50


Poster Session III - Clinical Vignettes

Exhibit Hall

7:00am-9:00am (Presenters at posters from 7:30am – 8:30am)

INTESTINE/COLON/IBD

165 UNDIFFERENTIATED HEPATIC CARCINOMA AFTER INFLIXIMAB AND IMURAN THERAPY FOR CROHN’S DISEASE. Eyad M. Altamimi, Ana Santa'Anna, Carol Portwine, Robert Issenman. Pediatric Department, McMaster Children Hospital-McMaster University, Hamilton, ON, Canada.

166 SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN PATIENTS ON 6-MERCAPTOPURINE MONOTHERAPY. Mehul Sheth, Vincent Biank. Pediatric Gastroenterology, Hepatology and Nutrition, Medical College of Wisconsin, Milwaukee, WI, USA.

167 COLITIS ASSOCIATED WITH MYCOPHENOLATE MOFETIL TREATMENT IN PEDIATRIC RENAL TRANSPLANT PATIENTS. Uma P. Phatak, Sohail Husain, Dinesh S. Pashankar. Pediatric Gastroenterology, Yale, New Haven, CT, USA.

168 CULLEN SIGN: AN UNUSUAL PRESENTATION OF SACROCOCCYGEAL TERATOMA. Liz Dancel2, Michael W. Gauderer3, Jonathan E. Markowitz1. 1Pediatric Gastroenterology, Greenville Children's Hospital, Greenville, SC, USA; 2Pediatrics, Greenville Children's Hospital, Greenville, SC, USA; 3Pediatric Surgery, Greenville Children's Hospital, Greenville, SC, USA.

169 LOW DOSE NALTREXONE FOR TREATMENT OF DUODENAL CROHN’S DISEASE IN A PEDIATRIC PATIENT. Naim Alkhouri, Shadi Mayacy, Lori Mahajan. Pediatric Gastroenterology, Cleveland Clinic, Celveland, OH, USA.

170 EPIPLOIC APPENDAGITIS (EA) - FIRST REPORT OF A RARE AND CONFUSING ENTITY IN TWO PEDIATRIC PATIENTS. M. Shah, S. Patel. Pediatrics, Loma Linda University, Loma Linda, CA, USA.

171 PULMONARY NODULES IN 3 ADOLESCENTS WITH CROHN’S DISEASE. Husam Mallah, Marilyn Brown, Thomas Rossi. Pediatric GI, University of Rochester, Rochester, NY, USA.

172 SERIOUS RECTAL BLEEDING COMPLICATING SUCTION RECTAL BIOPSY IN A CHILD. Ahmed Dahshan. Oklahoma University, Tulsa, OK, USA.

173 THE TWISTS AND TURNS OF PEDIATRIC VOLVULUS. Brian P. Regan, Brian Gilchrist, Alex Flores. Pediatric Gastroenterology and Nutrition, Tufts Medical Center Floating Hospital for Children, Boston, MA, USA.

174 GASTROINTESTINAL AND VASCULAR COMPLICATIONS IN JUVENILE DERMATOMYOSITIS. James Lamphear, Karla AuYeung, Carolyn Sullivan. Pediatric Gastroenterology and Nutrition, Walter Reed Army Medical Center, Washington, DC, USA.

51

175 REPEATED EPISODES OF NECROTIZING ENTEROCOLITIS IN AN INFANT WITH

GASTROSCHISIS. Justin DeVito. Pediatric Gastroenterology, Walter Reed Army Medical Center, Washington, DC, USA.

176 ISCHEMIC COLITIS IN A ONE YEAR OLD. Javier J. Monagas1,2, Allan J. Rosenberg1,2. 1Pediatrics, LSUHSC, New Orleans, LA, USA; 2Pediatric GI, Children's Hospital, New Orleans, LA, USA.

177 OMPHALOMESENTERIC REMNANT: AN UNCOMMON CAUSE OF UMBILICAL DRAINAGE. Shabina Walji-Virani, Eugene G. Sheffield, Joseph T. Murphy, Michael A. Russo. Gastroenterology, University of Texas Southwestern/Children’s Medical Center, Dallas, TX, USA.

178 LABIAL SWELLING: A RARE PRESENTATION OF METASTATIC CROHNS DISEASE(CD). Shaista Safder, Joan Tamburro, Patrice Tyson. Case Medical Center, Cleveland, OH, USA.

179 INFLAMMATORY BOWEL DISEASE IN A CHILD WITH A HISTORY OF IMPERFORATE ANUS. Yonathan Fuchs, James Markowitz, Toba Weinstein. Pediatric gastroenterology, North Shore Long Island Jewish, New Hyde Park, NY, USA.

180 SUSPECTED FPIES IN A 3 MONTH OLD FOLLOWING INGESTION OF RICE CEREAL AND A HOMEOPATHIC THERAPY. Christine Waasdorp, Edward Hoffenberg, Jason Soden. Pediatric Gastroenterology, University of Colorado Denver School of Medicine, Aurora, CO, USA.

181 ULCERATIVE COLITIS AND ACUTE PANCREATITIS IN A PEDIATRIC PATIENT AT PRESENTATION; A RARE ASSOCIATION. Azam Soroush. Pediatrics, Jersey Shore University Medical Center, Neptune, NJ, USA.

182 CELIAC DISEASE: A SNAKE IN THE GRASS. Charina M. Ramirez, Bradley Barth. Pediatric Gastroenterology, University of Texas Southwestern, Dallas, TX, USA.

52


Concurrent Session III – New NASPGHAN Guidelines: The Current Status Moderators: Barbara Kaplan, MD and Steven Schwarz, MD

Grand Ballroom A 8:30am-10:00am

Pediatric GERD Colin Rudolph MD, PhD, Children’s Hospital of Wisconsin

Learning Objectives 1. To review new evidence-based recommendations for the diagnosis of pediatric GERD 2. To describe changes in symptom-based diagnostic and management approaches for pediatric

GERD 3. To discuss changes in practice recommended in new pediatric GERD guidelines

H. pylori infection in children Nicola Jones MD, The Hospital for Sick Children, Toronto

Learning Objectives 1. Identify revised consensus on diagnostic testing for H. pylori infection 2. Characterize antibiotic resistance and use of H. pylori antibiotic sensitivity testing 3. Review the current combined antibiotic and PPI treatment regimen.

Cyclic vomiting syndrome B Li MD, Children’s Hospital of Wisconsin & Gisela Chelimsky MD, Rainbow Babies & Children’s Hospital

Learning Objectives 1. Identify revised definition of cyclic vomiting syndrome 2. Discuss consensus on the diagnostic approach to and disorders that mimic CVS 3. Review new therapeutic options including abortive and prophylactic approaches

53


Concurrent Session III – Management of Portal Hypertension Moderators: Fred Watanabe MD and Harpreet Pall MD

Grand Ballroom B 8:30am-10:00am

Complications of portal hypertension Vicky Ng MD, The Hospital for Sick Children, Toronto

Learning Objectives 1. Provide a definition of portal hypertension (including Doppler imaging) 2. Describe mediators involved in the pathogenesis of portal hypertension 3. Characterize the clinical manifestations of portal hypertension

Medical management of portal hypertension Simon Ling MD, The Hospital for Sick Children, Toronto

Learning Objectives 1. Review strategues for the identification of children at high risk of varices 2. Review the prophylaxis of variceal hemorrhage 3. Review the medical treatment of children with acute variceal hemorrhage

Non-medical management of portal hypertension Naveen Mittal MD, Children’s Medical Center, Dallas

Learning Objectives 1. Review current shunting techniques used to treat portal hypertension 2. Review the role of transplant in portal hypertension 3. Review current surgical shunting procedures used in children

54


Concurrent Session III - Intestine/Colon/IBD

Moderators: Edwin deZoeten, MD and Michael Stephens, MD

Seabreeze Room 8:30am-10:00am

183 BENEFICIAL EFFECTS OF DNA METHYLTRANSFERASE INHIBITOR (DNMTi)

THERAPY ON EXPERIMENTAL COLITIS. Joel Friedlander1, Edwin de Zoeten1, Liqing Wang2, Wayne Hancock2. 1Division of Gastroenterology & Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, USA; 2Pathology and Laboratory Medicine, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA, USA.

184 E-CADHERIN IS ASSOCIATED WITH CROHN’S DISEASE AND GENETICALLY INTERACTS WITH NOD2. Aleixo M. Muise1, Thomas Walters1, Wioletta Glowacka1, Anne Griffiths1, Bo-Yee Ngan1, Hui Lan Lan2, Wei Xu2, Mark Silverberg2, Daniela Rotin1. 1Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canada; 2Medicine, Mt Sinai, Toronto, ON, Canada.

185 SEVERE PEDIATRIC ULCERATIVE COLITIS: A PROSPECTIVE MULTICENTER STUDY OF OUTCOMES AND PREDICTORS OF RESPONSE. Dan Turner, D. Mack, K. Uusoue, J. Hyams, L. Leleiko, S. T. Leach, T. D. Walters, A. S. Day, W. Crandall, J. Markowitz, M. Silverberg, A. R. Otley, P. Mamula, A. M. Griffiths. SickKids Hospital-coordinating site, Toronto, ON, Canada.

186 TREATMENT WITH AN OX40 AGONISTIC ANTIBODY UP-REGULATES FOXP3+ REGULATORY T CELLS AND ATTENUATES EXPERIMENTAL COLITIS. Zili Zhang1, Wenwei Zhong1, Keith Wegmann2, Dave Hinrichs2. 1Pediatrics, Oregon Health & Science University, Portland, OR, USA; 2Immunology, Portland VA Medical Center, Portland, OR, USA.

CDHNF/CCFA Award for New Investigators OX40 AND TH17 CELL ACTIVATION IN INFLAMMATORY BOWEL DISEASE. Zili Zhang, MD, Oregon Health and Science University, Portland, OR.

123 RECTAL SENSORY THRESHOLD FOR PAIN MEASURED BY BAROSTAT IS A BIOLOGICAL MARKER OF IRRITABLE BOWEL SYNDROME AND FUNCTIONAL ABDOMINAL PAIN IN CHILDREN. Ugur Halac, Angela Noble, Lise Giguère, Christophe Faure. Pediatric Gastroenterology, Hepatology and Nutrition, Hôpital Sainte-Justine, Université de Montréal, Montréal, QC, Canada.

55

NOTES

56


Concurrent Session IV – Aerodigestive approaches to dysphagia and aspiration Moderators: Colin Rudolph MD, PhD and Khalid Khan MD

Grand Ballroom A 10:30am-12:00pm

The evaluation and management of children with feeding disorders Richard Noel MD, PhD, Medical College of Wisconsin

Learning Objectives 1. Review normal progression of swallowing skill acquisition / changes in anatomy 2. Review assessment of swallowing in infants and young children with dysphagia 3. Review video swallow study – no penetration or aspiration 4. Discuss management of this child in the context of his/her therapies, feeding skills, growth,

and respiratory issues

Evaluation and management of pulmonary complications of feeding and/or gastroesophageal reflux Ajay Kaul MD, Cincinnati Children’s Hospital Medical Center

Learning Objectives 1. Discuss differential diagnosis 2. Review and discuss investigations for silent aspiration, decreased pharyngeal and vocal fold

sensation and aspiration, role of bronchoscopy, impedance, high resolution CT 3. Management from gastrointestinal perspective: dietary changes, oral motor therapy, acid

blockade, gastrostomy tube Evaluation and management of a child with anatomic abnormalities of the aerodigestive tract Rachel Rosen MD, Children’s Hospital Boston

Learning Objectives 1. Discuss airway anatomic anomaly (laryngeal cleft/TEF, paralyzed vocal cord) 2. Identify gastrointestinal anatomic anomalies (esophageal atresia/TEF, gastric pull up

procedure) 3. Describe the clinical impact of GER (D), eosinophilic esophagitis, vomiting, feeding

intolerance 4. Identify ENT concerns regarding above

57


Concurrent Session IV – Post-transplant gastrointestinal complications Moderators: Daniel Kamin, MD and Phil Rosenthal, MD

Grand Ballroom B 10:30am-12:00pm

The gastrointestinal manifestations of graft-versus-host disease (GVHD) William Berquist MD, Lucile Packard Children’s Hospital, Palo Alto

Learning Objectives 1. Review the causes, time course and clinical presentation of GVHD 2. Describe the endoscopic and histologic manifestations and treatment 3. Describe extraintestinal manifestations of GVHD (hepatic) and treatment

Post-transplant lymphoproliferative disease (PTLD): An update Estella Alonso MD, Children’s Memorial Hospital, Chicago

Learning Objectives 1. Review PTLD and its changing incidence and clinical presentations in children 2. Describe the radiographic, biopsy, and PCR testing to confirm PTLD 3. Discuss the treatment options for PTLD

Motility and intestinal transplant Samuel Kocoshis MD, Cincinnati Children’s Hospital Medical Center

Learning Objectives 1. Review the changes in motility in the transplanted and rejected intestine 2. Describe testing modalities used to confirm dysmotility 3. Discuss available treatment options for dysmotility in transplanted bowel (including

treatment of sepsis)

58


Concurrent Session IV - Pancreas/Nutritional Disorders and Cystic Fibrosis Moderators: Sohail Husain, MD and Daniel Jackson, MD

Seabreeze Room 10:30am-12:00pm

187 PATHOLOGIC PROTEASE ACTIVATION DURING IN VIVO PANCREATITIS IS

DEPENDENT UPON CALCINEURIN ACTIVATION. Ahsan U. Shah, Alexander J. Park, Zahir M. Mannan, Wayne M. Grant, Sohail Z. Husain. Pediatrics, Yale University, New Haven, CT, USA.

188 GASTRODUODENAL ENDOSCOPIC AND HISTOLOGIC FINDINGS IN CHILDREN WITH CYSTIC FIBROSIS. Jennifer deBruyn1, Cynthia Trevenen2, Helen Machida1. 1Pediatrics, Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada; 2Pathology and Lab Medicine, University of Calgary, Calgary, AB, Canada.

189 PANCREATIC LESIONS IN A CFTR-/- PIG MODEL. Aliye Uc1, David K. Meyerholz2, Christopher S. Rogers3, David A. Stoltz3, Peter J. Taft3, Randall S. Prather5, Michael J. Welsh3,4. 1Pediatrics, University of Iowa, Iowa City, IA, USA; 2Pathology, University of Iowa, Iowa City, IA, USA; 3Internal Medicine, University of Iowa, Iowa City, IA, USA; 4Howard Hughes Medical Institute, University of Iowa, Iowa City, IA, USA; 5Animal Sciences, University of Missouri, Columbia, MO, USA.

CDHNF/Nestle Nutrition Award for Young Investigators EFFECTS OF DIETARY FRUCTOSE REDUCTION IN CHILDREN WITH HEPATIC STEATOSIS. Miriam Vos, MD, Emory University, Atlanta, GA.

190 LONG TERM EFFECTS OF VITAMIN SUPPLEMENTATION OF HIV-INFECTED MOTHERS ON CHILDHOOD MORTALITY AND MORBIDITY. N. Sabery1,2, K. Manji3, E. Hertzmark2, G. Msamanga3, W. Fawzi2, C. Duggan1,2. 1Gastroenterology and Nutrition, Children's Hospital, Boston, MA, USA; 2Harvard School of Public Health, Boston, MA, USA; 3Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania.

George Ferry Young Investigator Award EFFECT OF ILEAL TRANSPOSITION ON THE PATHOPHYSIOLOGY OF NUTRITION ASSOCIATED HEPATIC STEATOSIS. Rohit Kohli, MD, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

59

NOTES

60


Clinical Challenge Luncheons See ticket for room assignment

12:00pm-1:30pm 1. Allergic bowel disease

Moderator: Qian Yuan MD, PhD John Kerner MD, Lucile Packard Children’s Hospital Sandeep Gupta MD, Riley Children’s Hospital, Indianapolis 2. Therapeutic approaches to irritable bowel syndrome: We feel your pain Moderator: Christopher Jolley MD Adrian Miranda MD, Children’s Hospital of Wisconsin Nader Youssef MD, Atlantic Health System, Morristown, NJ 3. Evaluating neonatal liver failure Moderator: Grzegorz Telega MD Nada Yazigi, MD, Cincinnati Children’s Medical Center 4. Polyps and polyposis syndromes Moderator: Steve Erdman MD Thomas Attard MD, Nebraska University Sherry Huang MD, UC-San Diego Carol Durno MD, Mt. Sinai Hospital, Toronto 5. How best to treat nonacid reflux? Moderator: Judith O’Connor MD Rachel Rosen MD, Children’s Hospital Boston Hayat Mousa MD, Nationwide Children’s Hospital 6. Managing complications of GERD Moderator: David Gremse MD Eric Hassall MD, University of British Columbia Vasu Tolia MD, Pediatric GI Center - Detroit 7. Managing gastrointestinal complications of Cystic Fibrosis Moderator: Ashish Patel, MD John Pohl MD, Scott and White Hospital, Temple, TX Sarah Jane Schwarzenberg, MD, Minnesota Children’s Hospital 8. Biliary disease: Stones and groans in the upper right quadrant in the upper right quadrant James Heubi MD, Cincinnati Children’s Hospital Medical Center Sonia Michail, Children’s Medical Center, Dayton 9. Metabolic liver disease: When to consider the diagnosis and how to make it Moderator: Shikha Sundaram MD Binita Kamath MD, Children’s Hospital of Philadelphia Saul Karpen MD, Texas Children’s Hospital 10. Refractory constipation; Where does it stop? Moderator: Bankole Osuntokun MD Rina Sanghavi, MD, Children’s Medical Center, Dallas Manu Sood MD Children’s Hospital of Wisconsin

61

NOTES

62


Concurrent Session V – Inflammatory Bowel Disease (IBD) – Clinical Scenarios: How do you treat?

Moderators: Paul Rufo, MD, Maria Oliva-Hemker, MD and David Ziring, MD

(In Memory of M. Susan Moyer, MD)

Grand Ballroom A 1:30 pm-3:00 pm

How do we manage a patient with IBD until mercaptopurines becomes therapeutic? William Faubion MD, Mayo Clinic

Learning Objectives 1. Identify risk and benefits of potential bridging strategies 2. Review the current literature on the risk of thiopurines 3. Discuss the appropriate clinical scenario for above strategies

How do we best manage the patient with refractory Crohn disease? Ted Denson MD, Cincinnati Children’s Hospital Medical Center

Learning Objectives 1. Define the “refractory Crohn” patient, including “steroid-dependent” and “resistant” 2. Describe the use of methotrexate and infliximab for treatment of refractory patients 3. Review the therapeutic options for steroid-refractory hospitalized patient (cyclosporine,

tacrolimus, infliximab, surgery) 4. Review the rescue therapies in those failing to respond to biologics (adalimumab,

thalidomide)

How do we best manage the patient with refractory ulcerative colitis? Athos Bousvaros MD, Children’s Hospital Boston

Learning Objectives 1. Define the “refractory UC” patient 2. Describe the use of methotrexate and infliximab for treatment of refractory patients 3. Review the therapeutic options for steroid-refractory hospitalized patient (cyclosporine,

tacrolimus, infliximab, surgery) 4. Review the rescue therapies in those failing to respond to biologics (adalimumab,

thalidomide)

63


Concurrent Session V – Antibiotic therapy in gastrointestinal disease: What’s the evidence?

Moderators: John Udall, MD and Mary Zachos, MD

Grand Ballroom B 1:30 pm-3:00 pm

Antibiotics and inflammatory bowel disease (IBD) Anne Griffiths MD, The Hospital for Sick Children, Toronto

Learning Objectives 1. Review the use of antibiotics as initial therapy and for perianal disease in IBD 2. Characterize the evidence base for antibiotic use in fistula and stricture formation 3. Describe the evidence for usage of pre- / probiotics for treatment of IBD

Antibiotics and irritable bowel syndrome (IBS) Mark Pimentel MD, Cedars Sinai Medical Center

Learning Objectives 1. Describe the pathophysiology of post-infectious IBS 2. Identify antibiotic regimens currently being studied in the treatment of IBS 3. Discuss the evidence for use of pre- / probiotics for treatment of IBS

Clostridium difficile: How do you treat the patient with relapsing disease? Michael Farrell MD, Cincinnati Children's Hospital Medical Center

Learning Objectives 1. Define the incidence of relapsing C. difficile infections in hospitalized patients 2. Identify the current effective antibiotic regimens for relapsing C. difficile infection? 3. Discuss non-antibiotic regimens, including probiotics, IVIG, and cholestyramine

64


Concurrent Session V - Disorders of the Esophagus and Stomach

Moderators: Edda Fiebiger MD and Victor M. Piñeiro MD


191 MULTICENTER, DOUBLE-BLIND, RANDOMIZED, PLACEBO-CONTROLLED TRIAL

ASSESSING EFFICACY & SAFETY OF PROTON PUMP INHIBITOR LANSOPRAZOLE IN INFANTS WITH SYMPTOMS OF GASTROESOPHAGEAL REFLUX DISEASE . Susan R. Orenstein1, Eric Hassall2, Wanda Furmaga-Jablonska3, Stuart Atkinson4, Marsha Raanan4. 1University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 2BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada; 3Medical University of Lublin, Lublin, Poland; 4TAP Pharmaceutical Products Inc, Lake Forest, IL, USA.

192 EoE LAMINA PROPRIA CONTAINS INCREASED FIBROSIS. Samantha A. Woodruff1, Vincent Mukkada1, Kelley Capocelli2, Mark Lovell2, Glenn Furuta1. 1Pediatric Gastroenterology, Hepatology and Nutrition, The Children's Hospital, Aurora, CO, USA; 2Pediatric Pathology, The Children's Hospital, Aurora, CO, USA.

193 THE NATURAL HISTORY OVER 25 YEARS IN CHILDREN PRESENTING WITH GASTROESOPHAGEAL REFLUX DISEASE UNDER THE AGE OF 12 . Jingshing Wu4, Harland S. Winter1, Jennifer Wu4, David Culbertson5, James M. Perrin3, Paul A. Rufo2. 1Pediatric Gastroenterology, MassGeneral Hospital for Children, Boston, MA, USA; 2Pediatric Gastroenterology, Children's Hospital, Boston, MA, USA; 3Pediatrics, MassGeneral Hospital for Children, Boston, MA, USA; 4Harvard University, Cambridge, MA, USA; 5Middlebury College, Middlebury, VT, USA.

194 HOW MANY ESOPHAGEAL BIOPSIES ARE NECESSARY TO DIAGNOSE EOSINOPHILIC ESOPHAGITIS? Stephanie L. Page, Jennifer M. Colombo, Jennifer L. McCullough, James Daniel, Craig Friesen. Gastroenterology, Children's Mercy Hospitals & Clinics, Kansas City, MO, USA.

195 PREVALENCE OF ESOPHAGITIS IN CHILDREN WITH CELIAC DISEASE. Wael N. Sayej, Razan Alkouri, Robert D. Baker, Susan S. Baker. Digestive Diseases and Nutrition Center, Women & Children's Hospital of Buffalo, Buffalo, NY, USA.

65

NOTES

66


Concurrent Session VI – Billing and Coding 101, 102

Moderators: Leo Heitlinger MD and Roxanne Hecht MD


Kathleen Mueller, McVey Associates Learning Objectives 1. Describe billing codes for new endoscopic procedures 2. Describe billing codes for newly established gastrointestinal disease 3. Provide examples of complex patients that would stimulate mulitple billing codes

Concurrent Session VI – Education 2008: Is simulation the new wave? Moderator: B Li MD


Speakers: Jeffrey Burns MD, Alan Leichtner MD and Laurie Fishman MD, Children’s Hospital, Boston

Learning Objectives 1. Review the use of adult learning principles in pediatric GI fellowship training. 2. Identify endoscopic simulation products and studies that evaluate competence 3. Discuss practical teaching strategies for CME and in the clinical setting

Concurrent Session VI – Research mentoring, career development

& methodology workshop

Moderators: David Rudnick MD and Michael Narkewicz MD


Speakers: Patricia Robuck, PhD, MPH, NIDDK, National Institutes of Health, D. Brent Polk, MDVanderbilt University, Michael Narkewicz MD, Children’s Hospital, Denver

Learning Objectives 1. Review current NIH and non-NIH funding opportunities for junior faculty 2. Discuss career development strategies for both basic and clinical/translational faculty 3. Provide small group mentoring for both basic, clinical/translational research faculty

67


NASPGHAN Business Meeting CDHNF-NASPGHAN Awards Ceremony

Moderators: William Balistreri MD and John Barnard MD

Grand Ballroom A 5:00pm – 6:30pm

♦ Shwachman Award ♦ Distinguished Service Award ♦ Pediatric Research Advocacy Award ♦ AAP Murray Davidson Award ♦ Presentation of CDHNF Research Grants ♦ Corporate Recognition

7:00-10:00pm CDHNF 10th Anniversary Celebration/Dinner 7pm Reception Lanai 8pm Dinner/Dancing Grand Ballroom

68

NASPGHAN SCIENTIFIC EXHIBITS

HOURS:

THURSDAY, November 13 Exhibits open with Reception 5-7 pm

FRIDAY, November 14 Exhibits open 11:30 am – 4:00 pm

SATURDAY, November 15 Exhibits open 7:30 am – 12 noon

EXHIBITORS AS OF OCTOBER 28, 2008 Abbott Nutrition 217

American Partnership for Eosinophilic Disorders (APFED) 202

Applied Medical Technology 324

AstraZeneca 209

Bio-Rad Laboratories 200

Blank Children's Hospital 302

Calpro AS 117

Centocor, Inc. 119

CDHNF 418

Children's Hospital, Colorado 309

ChiRhoClin, Inc. 105

Crohn's and Colitis Foundation 205 of America (CCFA)

Digestive Care, Inc 127

Everidis Health Sciences 304

Given Imaging 223

HCA (Hospital Corporation of America) 218

Helen DeVos Children's Hospital 321

INOVA Diagnostics, Inc. 226

International Foundation for Functional Gastrointestinal Disorders (IFFGD) 121

JOLI Diagnostic, Inc. 111

Kimberly-Clark Health Care 326

Lippincott, Williams & Wilkins 408

Marshfield Clinic 206

Mead Johnson Nutritionals 201

Medical Measurement Systems USA, Inc. 319

MOOG Medical Devices 323

Nationwide Children's Hospital 309

Nestlé HealthCare Nutrition, Inc 125

NIDDK Information Clearinghouses 307

Nutra/Balance Products 224

Nutricia North America 311

Olympus America Inc 109

Procter & Gamble Pharmaceuticals 123

Prolacta Bioscience, Inc. 208

Prometheus 317

Romark Laboratories, L.C. 107

Salix Pharmaceuticals 222

Sandhill Scientific 204

Saunders/Mosby-Elsevier 227

Seattle Children's Hospital 420

Sigma-Tau Pharmaceuticals, Inc. 300

Specialty Surgical Products, Inc. 220

St. John's Mercy Children's Hospital 406

Takeda Pharmaceuticals North America 103

Walgreen's-Option Care 305

Vitaflo USA 225

69

EXHIBITOR LISTING AND PRODUCT DESCRIPTIONS

ABBOTT NUTRITION 217 625 Cleveland Avenue Columbus, OH 43215 US 614-624-7677 www.abbottnutrition.com

• Abbott Nutrition, the makers of Similac infant formulas invite you to discover the latest innovations in our products. Learn more about Elecare - now with DHA and ARA, Vital Jr with superior taste advantage and PediaSure for healthy growth and development. Our representatives look forward to welcoming you and discussing our products.

AMERICAN PARTNERSHIP FOR EOSINOPHILIC DISORDERS (APFED) 202 3419 Whispering Way Drive Richmond, TX 77469 US 713-498-8216 www.apfed.org

• American Partnership for Eosinophilic Disorders (APFED) is a non-profit organization dedicated to patients and their families coping with eosinophilic disorders. APFED strives to expand education, create awareness, and support research while promoting advocacy among its members.

APPLIED MEDICAL TECHNOLOGY 324 8000 Katherine Blvd Brecksville, OH 44141 US 440-717-4000 www.appliedmedical.net

• With over 25 years of enteral device development, Applied Medical Technology, Inc. is dedicated to delivering the latest innovations in medial device manufacturing. AMT products include: The Mini One low profile Balloon, Mini One Non-Balloon, Capsule Button and The AMT Bridle - the proven Simple and Safe Nasal Tube Retaining System

ASTRAZENECA 209 PO Box 15437 Wilmington, DE 19850-5437 US 800-456-3669 www.astrazeneca-us.com

• AstraZeneca produces a wide range of products that make significant contributions to treatment options and patient care. The company has one of the world's leading portfolios to treat cancer and gastrointestinal disorders, in addition to the areas of anesthesia, pain management, cardiovascular disease, respiratory and central nervous system disorders. You are invited to visit our exhibit to speak with a representative about our products.

BIO-RAD LABORATORIES 200 4000 Alfred Nobel Drive Hercules, CA 94547 US 800-2BIO-RAD www.bio-rad.com/diagnostics

• Bio-Rad Laboratories is a worldwide leader in specialty diagnostics. The company holds leadership positions in quality control management, diabetes testing, blood virus and autoimmune disease testing. Bio-Rad’s extensive range of autoimmune diagnostics products includes diagnostic tests for celiac, Crohn’s disease, ulcerative colitis and vasculitides.

BLANK CHILDREN'S HOSPITAL 302 1200 Pleasant Street Des Moines, IA 50304 US 515-241-5911

CALPRO AS 117 Arnstein Arnebergs Vei 30 Lysaker, 01366 Norway (+47) 40004279 www.calpro.no

• Products: The Calpro Calprotectin ELISA Test and The Calpro Calprotectin RAPID Test.

• Calprotectin is a dominant neutrophil protein that is stable in stools at RT. Small stool samples (5 gr) can be sent by ordinary mail to the lab where it is assessed by ELISA. A rapid test is under development and will be available soon.

• Determination of calprotectin is useful in the diagnosis and evaluation of disease activity in IBD patients. Normalisation of fecal calprotectin is a strong indicator of mucosal healing in IBD patients.

• Assessments of calprotectin is also useful to differentiate between IBS and IBD, and can therefore reduce unnecessary and costly colonoscopies.

CENTOCOR, INC. 119 800 Ridgeview Drive Horsham, PA 19044 US 610-651-6000 www.centocor.com

• Centocor is harnessing the power of world-leading research and biomanufacturing to deliver innovative biomedicines that transform patients' lives. The world leader in momoclonal antibody production and technology, Centocor, Inc. is a wholly owned subsidiary of Johnson & Johnson, a worldwide manufacturer of healthcare products.

70


CDHNF 418 PO Box 6 Flourtown, PA 19031

www.cdhnf.org

• NASPGHAN and CDHNF are dedicated to improving the care of infants, children and adolescents with digestive disorders by promoting advances in clinical care, research and education. Visit us at booth #418 and learn more about our newest professional and consumer education projects.

CHILDREN'S HOSPITAL, COLORADO 309 13123 E. 16th Avenue, B425 Aurora, CO 80045 US 800-624-6553 www.thechildrenshospital.org

• The Children’s Hospital, Colorado consistently ranks as one of the best children’s hospitals by U.S. News & World Report and is ranked #5 for digestive disorders. We have a nationally recognized, NIH-funded fellowship program and extensive clinical and research programs in liver disease and transplantation, IBD, celiac disease, eosinophilic esophagitis and mucosal immunology.

CHIRHOCLIN, INC. 105 4000 Blackburn Lane, Suite 270 Burtonsville, MD 20866 US 301-476-8388 www.chirhoclin.com

• ChiRhoClin, is the manufacturer of Secretin products. ChiRhoClin’s mission is to develop orphan drug products that aid, diagnose and treat gastrointestinal diseases. Our lead product is, ChiRhoStim® (Human Secretin). It is approved for Pancreatic Function Testing, ERCP’s, and Gastrinoma Testing. Finally, you can improve your MRCP images with Secretin-enhanced MRCP.

CROHN'S AND COLITIS FOUNDATION OF AMERICA (CCFA) 205 386 Park Avenue South, 17th Floor New York, NY 10016 US 212-685-3440 www.ccfa.org

• The Crohn's & Colitis Foundation of America is a non-profit organization dedicated to finding the cure for Crohn's disease and Ulcerative Colitis through researcch. The foundation also provides educational programs and materials for patients, medical professionals, and the general public. Educational materials may be found at the CCFA booth.

DIGESTIVE CARE, INC 127 1120 Win Drive Bethlehem, PA 18017 US 610-882-5950 www.digestivecare.com

• Digestive Care, Inc. (DCI) is a pharmaceutical company that manufactures PANCRECARB® (pancrelipase), delayed-release capsules-bicarbonate-buffered and enteric-coated microspheres. PANCRECARB® is indicated in the treatment of Exocrine Pancreatic Insufficiency such as: Chronic Pancreatitis, Fat Malabsorption, Post-Pancreatectomy, Post-Gastrointestinal By-Pass Surgery, and Cystic Fibrosis.

EVERIDIS HEALTH SCIENCES 304 2900 Brannon Avenue St. Louis, MO 63139 US 877-776-0101 www.everidis.com

• Everidis Health Sciences markets BioGaia, a comprehensive line of probiotics. BioGaia's innovative dosage forms include drops, drinking straws and chewable tablets.

GIVEN IMAGING 223 3950 Shackleford Road Suite 500 Duluth, GA 30096 US 770-662-0870 www.givenimaging.com

HCA (HOSPITAL CORPORATION OF AMERICA) 218 4333 Coach Light Trail Dayton, OH 45424 US 937-235-5890 www.hcakids.com

• Stop by our booth for more information about HCA Kids, a centralized recruitment office where you can make just one call to find out about opportunities in excellent facilities across the nation.

• HCA owns and manages over 160 hospitals in 21 states. We offer opportunities in big cities and rural areas, near sandy beachs and skyward reaching mountains. Excellent opportunities are available in private practices and two of the top academic medical centers in the nation.

71


HELEN DEVOS CHILDREN'S HOSPITAL 321 665 Seward Avenue, N.W. MC 521 Grand Rapids, MI 49504 US 800-788-8410 www.devoschildrens.org

• We are the region's largest children's hospital serving nearly three million children in a 37 county area and have 150 specialists in 40 specialty areas. Our Pediatric Gastroenterology Division has openings for a Division Chief and at least two staff physicians. In early 2011, we will move into a new, 206-bed children’s hospital currently under construction. We are a teaching hospital affiliated with Michigan State University which is developing a new four year medical school in Grand Rapids by 2010.

INOVA DIAGNOSTICS, INC. 226 9900 Old Grove Road San Diego, CA 92131 US 800-545-9495 www.inovadx.com

• INOVA Diagnostics, Inc. develops, manufactures and sells a complete menu of autoimmune disease diagnostic kits & components for screening and specific autoantibody determinations. Product groups include kits & components for rheumatoid arthritis, connective tissue disease, coagulation, gastrointestinal, vasculitis, endocrine and autoimmune liver disease.

INTERNATIONAL FOUNDATION FOR FUNCTIONAL GASTROINTESTINAL DISORDERS (IFFGD) 121 PO Box 170864 Milwaukee, WI 53217 US 414-964-1799 www.iffgd.org

• The International Foundation for Functional Gastrointestinal Disorders (IFFGD) is a nonprofit education and research organization dedicated to informing, assisting and supporting people affected by functional gastrointestinal and motility disorders.

JOLI DIAGNOSTIC, INC. 111 2451 Wehrle Drive Williamsville, NY 14221 US 716-639-0443 www.jolidiagnostic.com

• JOLI Diagnostic Inc. is a clinical and research laboratory specializing in gastroenterology testing. We offer many diagnostic tests (including: Elastase testing, Disaccharidase Determinations,

Pancreatic Enzyme Analysis, etc.) We now offer Celiac Testing Panels. Our laboratory focuses on excellent customer service, rapid turnaround time and competitive pricing.

KIMBERLY-CLARK HEALTH CARE 326 1400 Holcomb Bridge Road Roswell, GA 30076 US 770-587-8000 www.kchealthcare.com

LIPPINCOTT, WILLIAMS & WILKINS 408 619-465-6365

MARSHFIELD CLINIC 206 1000 North Oak Avenue Marshfield, WI 54449 US 800-782-8581 (x19774) www.marshfieldclinic.org

• Marshfield Clinic is a physician led multi-specialty group practice with over 775 physicians working at 41 locations throughout Wisconsin. We currently have pediatric gastroenterology openings at our center in Marshfield, Wisconsin. Clinical practice adjoins Children's Hospital. We offer an excellent benefit package with a very competitive salary.

MEAD JOHNSON NUTRITIONALS 201 2400 W. Lloyd Exp., B402 Evansville, IN 47721 US 812-429-7373 www.meadjohnson.com

• Mead Johnson Nutritionals welcomes you to the NASPGHAN-CDHNF Conference. Our vision is to be the world's leading provider of science-based pediatric nutrition products. We are dedicated to helping provide infants and children with the best start in life. We cordially invite you to visit our exhibit booth (#201) to discuss our featured products with our representatives.

MEDICAL MEASUREMENT SYSTEMS USA, INC. 319 383 Central Avenue South Suite LL40 Dover, OH 03820 US 603-750-0037 www.mmsusa.net

• MMS USA Inc. is providing a range of functional diagnostic solutions for GERD and GI manometry. MMS offers Orion II and Ohmega for ambulatory pH and Impedance recording and Solar GI to diagnose motility disorders in the whole GI tract. High Resolution Manometry (HRM) completes the MMS GI line.

72


MOOG MEDICAL DEVICES 323 4314 Zevex Park Lane Salt Lake City, UT 84123 US 801-264-1001 www.moog.com

• MOOG Medical Devices/ Zevex Enteral transforms life with its patented and proprietary medical device technologies. The Enteral Feeding division designs, manufactures and markets award-winning enteral nutrition delivery devices, including the EnteraLite® Infinity ambulatory enteral feeding pump and accessories. ZEVEX is a division of Moog Medical Devices Group.

NATIONWIDE CHILDREN'S HOSPITAL 309 700 Children's Drive Columbus, OH 43205 US 614-722-2000 www.nationwidechildrens.org

• The Division of Gastroenterology, Hepatology and Nutrition at Nationwide Children's is regarded among the leading centers for treating pediatric gastrointestinal motility disorders, inflammatory bowel disease, polyposis and short bowel syndrome. Ranked ninth in the nation by U.S. News & World Report, the division excels in advanced diagnostic and treatment techniques and ground-breaking clinical research.

NESTLÉ HEALTHCARE NUTRITION, INC 125 10801 Red Circle Drive Minnetonka, MN 55343 US 952-848-6000 www.nestlénutrition.com/us

• Nestlé Nutrition's ambition is to help people everywhere lead fuller, happier lives by developing and delivering innovative, effective, scientifically proven nutrition products with functional benefits. Our products are designed to help infants and young children grow and develop into healthy, robust adults; to promote peak mental and physical performance and to manage disease and enhance recovery.

NIDDK INFORMATION CLEARINGHOUSES 307 One Information Way Bethesda, MD 80892 US 800-860-8747 www.niddk.nih.gov

• The National Institute of Diabetes and Digestive and Kidney Diseases Information Clearinghouses, services of the National Institutes of Health, answer inquiries, develop and distribute publications, and work closely with professional and patient organizations and government agencies to coordinate resources about diabetes, digestive, and kidney and urologic diseases.

NUTRA/BALANCE PRODUCTS 224 7155 Wadsworth Way Indianapolis, IN 46219 US 800-654-3691 www.nutra-balance-products.com

• Nutra/Balance Products manufactures and distributes nutritionally enhanced products that include nutritional supplements for Full Liquid, Clear Liquid, Renal, Sugar-Free, Non Dairy Complete Nutrition and Fiber diets. The company's products include frozen and dry products geared to long term institutional care, acute, subacute and congregate care markets.

NUTRICIA NORTH AMERICA 311 9900 Belward Campus Drive Suite 100 Rockville, MD 20850 US 800-365-7354 www.nutricia-na.com

• Nutricia North America manufactures medical foods and infant formulas for the treatment of food allergy and gastrointestinal disorders. Nutricia's Neocate is the first non-allergenic, amino acid-based formula for infants and children with milk allergy and/or digestive diseases like eosinophilic esophagitis. Please visit booth #311 to learn more about Neocate products.

73


OLYMPUS AMERICA INC 109 3500 Corporate Parkway Center Valley, PA 18034 US 484-896-5000 www.olympusamerica.com

• Olympus Medical Systems Group provides endoscopy knowledge and solutions that enable hospital suites, ambulatory surgical centers and private practices to achieve exceptional clinical and financial outcomes across the continuum of care. Olympus offers diagnostic and therapeutic endoscopes and EndoTherapy accessories; service and repair solutions; Web-based products; integration services; cleaning and disinfection products and services; cost-effective financial solutions; and consulting services.

PROCTER & GAMBLE PHARMACEUTICALS 123 8700 Mason-Montgomery Road, Box 2010 Mason, OH 45040 US 513-622-0898 www.pg.com

• P&G Pharmaceuticals, a division of Procter & Gamble, Inc., is a $40-billion global leader in the development, manufacturing and marketing of a broad range of consumer goods. In prescription drugs, P&G is focusing on musculoskeletal, cardiovascular health, anti-infective therapies and women’s health initiatives.

PROLACTA BIOSCIENCE, INC. 208 605 E. Huntington Drive Monrovia, CA 91016 US 888-776-5228 www.prolacta.com

• Prolacta BioscienceTM is a life sciences company specializing in human milk formulations for use in the NICU. With the ground-breaking development of the first commercially available Human Milk Fortifier made from human milk. Prolacta® is dedicated to improving the outcome of neonatal care.

PROMETHEUS 317 8410 Carroll Park Drive San Diego, CA 92121 US 888-423-5227 www.prometheuslabs.com

• Prometheus Laboratories Inc. is a specialty pharmaceutical company committed to developing new ways to help physicians individualize patient care. Prometheus focuses on the treatment, diagnosis and detection of gastrointestinal, autoimmune and inflammatory diseases and disorders.

ROMARK LABORATORIES, L.C. 107 3000 Bayport Drive, Suite 200 Tampa, FL 33607 US 813-282-8544 www.romark.com

• Romark Laboratories, a privately held biopharmaceutical company, has discovered and developed a new class of small molecule antivirals known as thiazolides. Romark is developing nitazoxanide, the first thiazolide, for the treatment of chronic hepatitis C. Alinia® (nitazoxanide) is approved and marketed for the treatment of Cryptosporidium parvum and Giardia lamblia infection.

SALIX PHARMACEUTICALS 222 1700 Perimeter Park Drive Morrisville, NC 27560 US 919-862-1000 www.salix.com

SANDHILL SCIENTIFIC 204 9150 Commerce Center, Circle #500 Highland Ranch, CO 80129 US 303-470-7020 www.sandhillsci.com

• Sandhill Scientific has been a worldwide leader in the field of gastroenterology diagnostics for over 25 years. Known for innovative technologies, the company continues to lead the industry in high definition G.I. diagnostic systems. Our exclusive, cutting-edge impedance (Z) technology enables you to precisely differentiate patient diseases presenting with similar esophageal symptoms. The revolutionary Sleuth System, which incorporates this Z technology, provides Total Reflux Monitoring, helps quantify both acid and non-acid reflux activity and produces comprehensive symptom association data. Sandhill Scientific provides the tools which allow clinicians to make an accurate diagnosis.

SAUNDERS/MOSBY-ELSEVIER 227 3473 Sitio Borde Carlsbad, CA 92009 US 760-944-9906 www.elsevier.com

74


SEATTLE CHILDREN'S HOSPITAL 420 PO Box 50020 M/S S-217 Seattle, WA 98145-5020 US 206-987-2000 www.seattlechildrens.org

• Consistently ranked as one of the best children’s hospitals in the country by U.S. News & World Report, Children’s serves as the pediatric referral center for Washington, Alaska, Montana and Idaho. Children’s has been delivering superior patient care for more than 100 years, advancing new discoveries and treatments through pediatric medical research, and serving as a primary teaching, clinical and research site for the Department of Pediatrics at the University of Washington School of Medicine.

SIGMA-TAU PHARMACEUTICALS, INC. 300 9841 Washingtonian Blvd Suite 500 Gaithersburg, MD 20878 US 800-447-0169 www.sigmatau.com

• VSL#3 is the probiotic medical food for the dietary management of Ulcerative Colitis (UC), Irritable Bowel Disease (IBS), or an Ileal Pouch. VSL#3 is imported by Sigma-Tau Pharmaceuticals, Inc., a subsidiary of Sigma-Tau S.p.A.

SPECIALTY SURGICAL PRODUCTS, INC. 220 1131 N. US Hwy 93 Victor, MT 59875 US 406-961-0102 www.ssp-inc.com

• Introducing the Aus Systems rbi2 Suction Rectal Biopsy System with a convenient reusable handpiece combined with a disposable tip that contains a razor sharp balde, allowing for a clean cut every time. The system is low maintenance, has simple cleaning requirements and constant 6ml suction, assuring consistent, dependable biopsy specimens.

ST. JOHN'S MERCY CHILDREN'S HOSPITAL 406 645 Maryville Centre Suite 100 St. Louis, MO 63141 US 800-851-2382 www.stjohnsmercy.org

TAKEDA PHARMACEUTICALS NORTH AMERICA 103 645 N. Field Lane Lake Forest, IL 60045 US www.tpna.com

• Based in Deerfield, Ill., Takeda Pharmaceuticals North America, Inc. is a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, the largest pharmaceutical company in Japan. In the United States, Takeda currently markets products for diabetes, insomnia, wakefulness and gastroenterology. Through the Takeda Global Research & Development Center, Inc. the company has a robust pipeline with compounds in development for diabetes, cardiovascular disease and other conditions. Takeda is committed to striving toward better health for individuals and progress in medicine by developing superior pharmaceutical products. To learn more about the company and its products, visit www.tpna.com.

WALGREEN'S-OPTION CARE 305 485 Half Day Road Suite 300 Buffalo Grove, IL 60089 US 847-353-5102 www.walgreenshomecare.com

• Walgreens-OptionCare is a leading U.S. home care company. With strong clinical programs and a commitment to quality patient care, we balance the needs of the patient with those of the healthcare team to achieve optimal outcomes. We offer accredited Home Infusion, Nutrition Support and Respiratory Therapy/Oxygen in 36 states.

VITAFLO USA 225 123 East Neck Road Huntington, NY 14743 US 631-693-2002 www.vitaflousa.com

• Unique Foods for Individuals with Unique Needs - Vitaflo USA is dedicated to serving the patient community through innovative and specialized formulas for disease related malnutrition, gastrointestinal disorders and rare metabolic disorders. Our unique products, MCT Procal and Lipistart, offer flexibility and convenience while meeting the unique dietary requirements related to disorders of fat malabsorption.

75

NOTES

76

AUTHOR INDEX

Name/Abstract # A Abdel-Rahman, S M. 84 Abdullah, B 21 Abernathy, F 162 Abu-hammour, W 156 Ackerman, S J. 163 Adamiak, T 132 Adams, P 77 Adcock, K 2 Adler, J 138 Aglingary, N 15 Agrawal, B 73 Ahrens, W 47 Al-Hawary, M M. 138 Al-Tawil, Y 145 Alexis, R 157 Ali, S 117 Alkalay, M J. 72 Alkhouri, N 110, 169 Alkouri, R 195 Allen, C 126 Almadhoun, O F. 105 Alpini, G 127 Altamimi, E M. 165 Alvarez, F 68 Amaro-Galvez, R 35 Ammar, M 42 Ammoury, R 6 Andersen, J 36, 53 Andersson, H C. 52 Andre, L A. 85 Ao, Z 97 Arora, S 50 Arumugam, R 132 Ashworth, L A. 130 Aspirot, A 91 Atay, O 40

Atkinson, S 191 Au Yeung, K J. 50, 174 Avolio, J 28 B Bae, J 53 Baker, R D. 13, 195 Baker, S 120 Baker, S S. 195, 13 Balint, J P. 48 Ballard, S A. 75, 94 Banda, J 106, 112 Barken, D M. 143 Barnard, J 126 Barth, B 182 Beg, M 88 Benchimol, E I. 28 Beneck, D 41 Benedir, A 66 Bensen, N 22 Berezin, S H. 79 Berk, T 15 Berquist, W 107 Best, C 32, 160 Biank, V 106, 112, 166 Bishop, P 69 Bizzarri, B 18, 154 Blain, S W. 11 Blake, K 35 Blumenthal, J 99 Boamah, L M. 150 Boas, S 35 Bostwick, H E. 79 Bousvaros, A 130 Bouthillier, L 98 Boyd, D 31 Bozorgnia, L 20

77

Brandt, M 39 Branham, C 74 Brown, C 132 Brown, M 113, 118, 121, 171 Brown, R 44 Brumbaugh, D E. 114 Buchman, A 96 Budge, A 127 Burchett, S K. 130 Burrin, D G. 101 Burwinkle, T 23 Butler, K 15 C Capocelli, K 192 Caras, S D. 31 Carpentieri, D 141 Carter-Kent, C A. 110 Çeliker, M Y. 119 Chandrasoma, P 73 Chawla, A 12, 119 Chelimsky, G 8, 86, 87, 147 Chelimsky, T 86, 87 Chen, L 124 Choi, H 103 Choi, S 103 Christie, D L. 75 Chumpitazi, B P. 39, 80 Cocjin, J 78 Coffey, M M. 75 Cold, C J. 43 Colin, R 89 Colombo, J M. 1, 83, 85 164, 194 Columbo, J M. 82 Comer, G M. 2, 3, 4, 5 Congxian, J 134 Cope-Yokoyama, S D. 57 Cox, S 74 Crandall, W 185 Croffie, J M. 14

Cuevas, C 145 Culbertson, D 193 Cummings, O 64 Cunningham, A 91 Czyzewski, D 80 D Dahshan, A 172 Daly, M 137 Dancel, L 168 Daniel, J 194 Daniel, J F. 1, 164 Dave, M 138 David, K 63 Davis, M 14 Day, A S. 185 de 'Angelis, N 154 de Lorimier, A 50 de Zoeten, E 183 de' Angelis, G 18, 154 de' Angelis, N 18 Debra, T L. 84 deBruyn, J 188 Deivanayagam, S 129 DeVito, J 175 Di Lorenzo, C 48, 76, 77, 78, 91 Diaz-Miron, J 39 Diaz-Sotomayor, M 97, 120 Dillman, J R. 138 Donovan, K 9 Dougherty, M 117 Doughty, A 133 Dowling, P 81 Drack, A 60 Du, J 126 Duggan, C 190 Dukhande, V 67 Dunitz, J 32 Dunn, H 28 Duong, S 144

78

Dupen, M M. 75 Durno, C 15, 16 Dutta, A 125 E Eagle, L 159 Easley, D 155 Eghtesad, B 110 Eidelwein, A 145 Erdman, S H. 48 Esplen, M 15 Essers, J 137 Estalilla, O C. 116 F Farahan, R 67 Faubion, W 132 Faure, C 123 Fawzi, W 190 Fecteau, A 66 Feld, A D. 75 Feranchak, A 125, 127 Fernandez, S J. 91 Fernandez, S 93 Ferris, M J. 58 Ferry, G 140 Field, D 92 Fillon, S 163 Finegold, M J. 104 Fish, D 132 Fishbein, M 74 Fishman, D S. 29, 34, 104 Flass, T 45 Flores, A 173 Fong, J 146 For, N 64 For the Nash, C 63 Fornaroli, F 18, 154 Fortgang, I S. 52 Fraker, C 74

Friedlander, J 183 Friesen, C 1, 81, 84, 85, 158, 164, 194 Friesen, C A. 82, 83 Frost, K 28 Fu, C 4 Fuchs, Y 179 Fuentebella, J 111 Fullmer, E 22 Fung, J 110 Furmaga-Jablonska, W 191 Furuta, G 163, 192 G Gaillard, P 32 Gallinger, S 16 Garcia, J 109 Gauderer, M W. 168 Geffner, M 20 Ghafoor, S 55 Gibbons, T 7 Giblin, J 2 Giguère, L 123 Gilchrist, B 173 Gilger, M 29, 120, 124, 140 Gill, R 144, 148 Glassman, M S. 79 Glowacka, W 184 Gold, B 7, 99 Gomez, R 91 Gomez-Esquivel, R D. 108 Gopalareddy, V 47 Grand, R 130, 137 Grant, W M. 30, 187 Grayson, P 83 Greenley, R N. 133 Gregas, M C. 130 Grenawalt, J 163 Gress, F 11 Griffiths, A M. 28, 142,184, 185 Grossova Garie, S 139

79

Guatelli, F 18 Gullati, R 8 Gupta, N 136, 149 Gupta, S 6 Gyrda, Y 12 H Halac, U 123 Halata, M S. 79 Hamaker, B 97 Hancock, W 183 Hansen, M 145 Hardy, K 35 Hart, K 9, 10 Harwood, J 69 Hashemi, I 26 Hassall, E 191 Haws, R 21 Heaton, N 70 Heikenen, J 132, 43 Heller, E 86, 87 Herline, A J. 131 Hernandez, E 109 Hertzmark, E 190 Hess, T 56 Heubi, J 35 Heyman, M B. 136, 149 Higgins, P 134, 135 Himes, R W. 57, 104 Hinrichs, D 186 Hinz, M 3 Hjelmgren, B 96 Hoffenberg, E J. 45, 151, 180 Holme, B 32 Holter, S 16 Holtz, L R. 27 Horn, D S. 14 Horton, T M. 34 Huang, J S. 93 Huang, T E. 116

Hupertz, V 40, 110 Hurt, T 159 Husain, S 167 Husain, S Z. 30, 33, 187 Hussain, M 95 Hyams, J 185 Hyman, P 44, 71 I Inge, T 65 Iqbal, J 95 Issenman, R 165 Iyer, K 96 J Jacobson, D L. 130 Jahoor, F 97 Jain, A K. 101 James, L 5 Jatla, M 23 Jennifer, S V. 84 Jensen, M K. 17 Jeong, J 54 Jiang, B 126 Jibaly, R 156 John, S D. 108 Johnson, L 134 Johnson, V 41 Jones, E M. 34 Jones, N 66 K Kagalwalla, A F. 56, 76 Kalra, M 65 Kang, G H. 93 Karjoo, A 88 Karjoo, M 88 Karl, S 102 Kate, D 10 Katz, M 5

80

Kaul, A 90 Kay, M 40 Kearns, G 2, 5, 84 Keith, B 44 Kellermayer, R 59 Kelsen, J R. 139 Kenche, H 162 Kerner, J 51, 111 Keshen, T 129 Kesselring, S 88 Kevan, E N. 24 Keys, L 96 Khan, K 132, 160 Kierkus, J 4, 3 Kieserman-Shmokler, C 23 Kim, G 149 Kim, J 54, 54, 103 Kim, K 134 Kirk, E 129 Kirkwood, C D. 27 Kjar, D 155 Kjerulf, K 26 Klein, S 129 Klooster, M 19 Kocoshis, S A. 24 Kohn, M 136 Kooros, K 113 Koslowe, O 41 Koyama, T 131 Kreh, R 7 Kresge, C 125, 127 Kriss, V 161 Kruijsen, M 144 Krupa, J 99 Kugathasan, S 137, 132, 133 Kum-Nji, P 3 Kumar, P 96 L LaChance, J 156

Lai, J 67 Lamphear, J 174 Lan, H 184 Lane, M 80 Langer, J 142 Langer, S L. 75, 94 Latif, S U. 30 Latino, M 35 Lawson, A 116 Lazare, F 144, 148, 95 Leach, S T. 185 Lee, C 35 Lee, J 137 Leleiko, L 185 Lemale, J 98 Leong, T 7 Lerret, S 106, 112 Levy, R L. 75, 94 Lewis, J 9, 10 Li, B U. 56 Li, H 3 Lin, Z 85 Ling, S C. 28 Ling, S 66 Lipeski, L 105 Liu, H 69 Lopez, Y 19 Lovell, M 61, 192 Lu, Y 130 Lucia, C 140 Lustig, R 136 M Machida, H 188 Mack, D 185 Macumber, I 146 Maguire, M 2, 5 Maguire, M K. 4, 3 Mahajan, L 40, 169 Mahomedy, S H. 3

81

Malecka-Tendera, E 100 Mallah, H 113, 118, 121, 171 Mamula, P 185, 139 Manji, K 190 Mannan, Z M. 30, 187 Marchand, V 68, 98 Marciano, T 144 Margolis, T 60 Marini, J 97 Mark, K 89 Markowitz, J 185, 179 Markowitz, J E. 168 Martin, S R. 68 Matulewicz, T 25 Maurins, C 21 Mayacy, S 169 Mazur, A 100 McCallum, R W. 85 McCracken, M 136 McCullough, J L. 1, 164, 194 McDuffie, A 124, 140 McGinniss, M J. 143 McLeod, R 142 McNeal, M M. 130 McRae, S 7 Medow, M S. 79 Megison, S 53 Mehta, T R. 7 Melin-Aldana, H 56 Meng, X 2, 4, 5 Meyer, A L. 130 Meyerholz, D K. 62, 189 Mezoff, A 38 Michail, S 162 Miranda, A 76, 78 Mirza, S 59 Mittal, N K. 72 Mohammed, B 129 Molleston, J 64, 63 Monagas, J J. 176

Moore, D D. 101 Morgan, W M. 131 Morganstern, J 12 Morrison, J L. 38 Morrow, S E. 131 Moulton, D E. 131 Mousa, H M. 48, 91 Moyer, S 150 Msamanga, G 190 Muise, A M. 184 Mukadam, G 70 Mukkada, V A. 163, 192 Muldoon, R L. 131 Murphy, J T. 177 Murray, K 64 N Naguib, G 129 Nakamura, R M. 143 Nam, C 103 Nanton, S 37, 102 Narkewicz, M 60 Narwal, S 49 Nasir, A 116 Nasr, S 35 Nebel, J 132 Neilan, N 1, 81, 82, 84, 158, 164 Nelson, S 56 Ng, V L. 66 Ngan, B 128, 184 Nguyen, K 144, 148 Nguyen, K K. 11, 157 Nichols, B 97, 120 Noble, A 123 Noel, R 17 Nowicki, M 69 Ntrivalas, E 22 Nugent, M 132 Nurko, S 9, 10, 76, 78

82

O O'Gorman, M 22 O'Riordan, M 87 Oh, K 54, 103 Opekun, A 120 Orenstein, S R. 191 Ortega, A 73 Ostanski, M 100 Otley, A R. 185 Ouimet, A 98 O’Gorman, M 5 P Page, S L. 1, 164, 194 Paliy, O 162 Palsson, O S. 75 Pan, H 143 Pan, X 95 Park, A J. 30, 33, 187 Park, R 132 Park, S 54, 103 Paschall, A 159 Pashankar, D 33, 167 Patel, A 107, 111 Patel, R 13 Patel, S 170 Penera-Rivera, T 105 Penn, D 58 Pentiuk, S 150 Perelstein, E 41 Perrin, J M. 193 Petrescu, M S. 52 Petrova, A 25 Phatak, U P. 167 Philichi, L 21 Phillips, J 32 Phillips, S 70 Phillips, T 70 Pietzak, M 20, 73

Pineault, M 98 Pineiro-Carrero, V M. 47 Pisharody, U 58 Platt, J F. 138 Pohl, J 23, 155 Polk, D B. 131 Pollock, J 74 Pollock, S 66 Portwine, C 165 Prather, R S. 62, 189 Punglia, D R. 138 Q Quadros, E 148 Quezada-Calvillo, R 97, 120 Quigley, J 161 Quiros-Tejeira, R E. 108 Qureshi, M A. 26 R Raanan, M 191 Radhakrishnan, K 110 Raghunath, N K. 79 Raijman, I 29, 104 Rajcevich, S 19 Ramakrishna, J 146 Ramirez, C M. 182 Ramos-Soriano, A 152 Rangwalla, S 134, 135 Rasquin, A 68 Rath, N 4, 5 Regan, B P. 173 Reid, R 94 Repka, M X. 60 Resnick, J M. 43 Rhue, M 90 Ringheanu, M 153 Ritz, S 56 Rivas, Y 144 Rivera-Bennett, M 132

83

Rizzuti, L 154 Robayo-Torres, C 97, 120 Robert, B 139 Robinson, Z 163 Rodriguez-Baez, N 117 Roettcher, D 6 Rogacki, K 21 Rogers, C S. 62, 189 Rosen, M J. 131 Rosen, R 9, 10 Rosenberg, A J. 176 Rosenman, M 6 Rosenthal, P 37, 60, 102 Rossi, T 159, 171 Rotin, D 184 Rubin, J 134 Rudolph, C D. 122 Rudolph, J A. 24 Rufo, P A. 193 Russell, H V. 104 Russell, R 144 Russo, M 36, 53 Russo, M A. 115, 177 Ruzyla, T 21 Ryan, P 81 S Sabery, N 190 Safder, S 8, 86, 87, 147, 178 Sahibzada, L U. 33 Sahin, F 22 Sally, T 89 Sanchez, J 109 Sander-Struckmeier, S 31 Santa'Anna, A 165 Saps, M 76, 77, 78 Sathe, M 53, 125 Sathe, M N. 36, 117, 127 Sayej, W N. 13, 195 Scaini, V 28

Scheimann, A 64 Scholz, C 139 Schurman, J V. 85, 1, 81, 82, 83, 164 Schwartz, D A. 131 Schwarz, K B. 60 Schwarz, S 144, 157 Schwarzenberg, S 32 Schwimmer, J 63, 64 Sentongo, T S. 56, 96 Sequeira, J 148 Setchell, K 70 Shah, A U. 30, 33, 187 Shah, A 56 Shah, M 19, 170 Shaheen, C 2 Shahzed, S 144 Shaker, R 89 Sharma, G C. 67 Shashidar, H 161 Sheffield, E G. 177 Shen, L 59 Shen-Tu, G 128 Sherman, P 16, 128 Sherwood, N E. 94 Sheth, M 17, 166 Shub, M 141 Shulman, R 80 Sikka, N 113 Silber, G 141 Silverberg, M 142, 185, 184 Silverman, A 89 Simpson, P 132 Sinatra, F 73 Singh, M 82 Singh, V 82 Sirlin, S 144 Skaggs, B 91 Smith, C 57 Smith, L 109 Sockolow, R 41

84

Sodek, J 128 Soden, J 61, 180 Sokol, R J. 61 Solomon, A 144 Sommi, M 154 Sood, M R. 71, 89, 122 Soroush, A 25, 181 Splawski, J 8 Springer, M A. 4 Stenerson, M 149 Stockton, M 153 Stockwell, J 7 Stoll, B 101 Stoltz, D A. 62, 189 Sulaiman, R 37 Sullivan, C 50, 174 Sullivan, J E. 4 Sullivan, L 155 Sultana, Z 141 Sundaram, S 114 Sze, D 107 T Taft, P J. 189 Talisetti, A 51 Tamburro, J 178 Tammara, B 2, 4, 5 Tatevian, N 59, 124 Taylor, D 81, 158 Taylor, D L. 85 Taylor, W 145 Telega, G 71, 106, 112 Telega, G W. 100 Thakkar, K 124, 140 Thapa, N 71 Thompson, J 109 Thompson, K 46 Tipnis, N 17 Toohey, M 25 Treem, W 144, 148

Treem, W R. 11 Treem, W 95 Trevenen, C 188 Triantafyllopoulou, M 22 Troendle, D 53 Tron, E 13 Tsou, M 140 Tung, J 132 Turner, D 28, 185 Tyson, P 178 U Uc, A 62, 189 Udall, J N. 116 Ueno, Y 127 Unalp-Arida, A 64, 63 Ursea, D I. 141 Uusoue, K 185 V Van Winckel, M 144 Veltkamp, J 53 Venkatasubramani, N 122 Venteer, J 127 Verma, R 23 Vilca-Melendez, H 70 Vincenzi, F 18, 154 Vineet, B 33 Vitola, B E. 129 Vittinghoff, E 136, 149 W Waasdorp, C 180 Walbert, L 74 Waljee, A 135 Walji-Virani, S 177 Walker, G 12 Walkiewicz-Jedrzejczak, D 132

Walters, T D. 185

85

Walters, T 184 Walters, T D. 142 Wang, D 27 Wang, L 183 Ward, R 2, 5 Ward-Smith, P 158 Waterland, R A. 59 Watson, K 140 Watts, M 23 Wegmann, K 186 Weidkamp, M 132 Weinstein, T 179 Welsh, M J. 62, 189 Wetzler, G 49 Whitehead, W E. 75 Williams, K 92 Williot, S 68 Wilson, C 46 Wine, E 128 Winter, H 139, 3 Winter, H S. 193 Wise, P E. 131 Woo, K 125 Woo, M 35 Woodruff, S 163 Woodruff, S A. 192 Wu, J 193, 193 Wu, L 126

Wu, Y P. 83 Wyllie, R 40 Wyneski, M 40 X Xanthakos, S 65 Xu, J 144, 148 Xu, W 184 Y Yacob, D 48 Yaffe, M 132 Yakovich, A 126 Yanni, G 19 Yeckes, A R. 151 Yii, M 70 Young, M M. 75 Youssef, N 76, 78 Yu, L 44 Yuwono, M 159 Z Zhang, Z 186 Zhong, W 186 Zimmermann, E M. 138 Zohar, R 128

86

table of contents - naspghan...of an educational activity are required to disclose relevant...

Documents