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TechTIPS 2006–2007 Biennial Report UC San Diego Technology Transfer and Intellectual Property Services 2006–2007 BIENNIAL REPORT

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Page 1: Technology Transfer and Intellectual Property Services · Technology Transfer and Intellectual Property Services ... //psynomics.com/about.php ... Technology Transfer and Intellectual

TechTIPS 2006–2007 Biennial Report

UC San Diego �

Technology Transfer and Intellectual Property Services2006–2007 BIennIal RePoRT

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The UC San Diego Technology Transfer advisory Committee (TTaC) is responsible for general oversight of the UCSD Technology Transfer Program. This standing committee is appointed by the chancellor and is chaired by the vice chancellor for Research. It meets periodically to assess UCSD technology transfer practices and guide the direction of the overall program.

Committee members — FY2007

aRT ellIS (Chair) Vice Chancellor, Research

MIChael BURkaRT Professor, Chemistry and Biochemistry

lInDa Dale Director, office of Contract and Grant administration

JaMeS hollan Professor, Cognitive Science

PaUl keDRoSky executive Director, William J. von liebig Center Jacobs School of engineering

MIChael kelneR Professor, Pathology

WIllIaM kUPeRMan Professor, Scripps Institution of oceanography Marine Physical laboratory

laWRenCe MIlSTeIn Professor, electrical and Computer engineering

Jane MooReS Interim Director, Technology Transfer and Intellectual Property Services

JeRRolD olefSky Professor, Medicine

fRIeDeR SeIBle Dean, Jacobs School of engineering

SUReSh SUBRaManI Interim Dean, Division of Biological Sciences

RoBeRT SUllIVan Dean, Rady School of Management

Committee members — FY2006

RIChaRD aTTIyeh (Chair) Vice Chancellor, Research

RoGeR Bohn Professor, Graduate School of International Relations and Pacific Studies

MIChael BURkaRT Professor, Chemistry and Biochemistry

lInDa Dale Director, office of Contract and Grant administration

ToM JaCkIeWICZ Chief of Staff, School of Medicine

PaUl keDRoSky executive Director, William J. von liebig Center Jacobs School of engineering

MIChael kelneR Professor, Pathology

WIllIaM kUPeRMan Professor, Scripps Institution of oceanography Marine Physical laboratory

eDUaRDo MaCaGno Dean, Division of Biological Sciences

laWRenCe MIlSTeIn Professor, electrical and Computer engineering

alan PaaU (Secretary) assistant Vice Chancellor Technology Transfer and Intellectual Property Services

RoBeRT SUllIVan Dean, Rady School of Management

John WooDS Vice Chancellor, Resource Management and Planning

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Message from TechTIPS ......................................... 3

Inventions ......................................................................... 4

Start-ups ............................................................................. 6

outreach ............................................................................ 8

financials ........................................................................�0

activities ..........................................................................��

appendix ........................................................................�2

University of California, San Diego

Technology Transfer and Intellectual Property Services (TechTIPS)2006–2007 BIennIal RePoRT

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2 invent.ucsd.edu

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TechTIPS 2006–2007 Biennial Report

UC San Diego 3

In fy2006 under alan Paau, the campus technology transfer office managed an in-creased portfolio of cases. TechTIPS recorded high numbers in disclosures of inventions and copyright works by UC San Diego researchers, in executed licenses granting in-dustry partners intellectual property rights to develop UCSD innovations, in patents issued by the United States Patent and Trademark office to protect novel UCSD inventions, and in gross revenues of intellectual property income.

During fy2006, TechTIPS completed the decentralization of invention management by the University of California office of the President (UCoP). Through this process, which began in the previous fiscal year, the campus office absorbed the existing San Diego cases that had been managed by UCoP as well as the management of all new and existing cas-es from campus researchers. The transfer of cases from oakland had a significant impact on our office, especially in terms of workload for the patent prosecution, licensing, contract compliance, and accounting groups. The pat-ent portfolio was augmented by an increased number of patent applications filed during fy2006—over �80 U.S. applications and nearly 90 foreign applications.

fy2007 was a transition year for TechTIPS while we experienced several changes in the office. In the midst of these challenges, the campus office continued to manage an ever-increasing portfolio of technologies. our numbers increased in several areas. Dis-closures received increased to 373 in fy2007 versus 345 in fy2006; along with increases in agreement and license activities. Patent

activities were mixed—with increased U.S. patents issued to a high of 64 patents in fy2007 versus 44 in fy2006, while foreign patents issued dropped to 62 from �48 in the previous period. our total patent filing activities remained flat at 267 in fy2007 versus 27� in fy2006, along with income of $26.7 million in fy2006 versus $26.3 million in fy2007.

The overall trends have been positive during these fiscal years. The efforts of our office and of the entire campus bode well for the continued transfer of promising new tech-nologies into the commercial sector. our activities translated into increased economic development, especially in our local region. Ten of the seventeen start-ups in fy2006, and five of the nine start-ups in fy2007 are based in the San Diego regional area.

as part of the greater university community, we have gained national prominence as a leading technology hub and have partici-pated in several forums on developing and promoting university-industry relations. a selection of our presentations and visitors are listed on pages 8–9. In addition to our national and international visitors, we have had a global impact in contributing to new medical products sold in europe and asia.

We thank our campus partners and welcome your feedback as we work together for the continued success of UCSD’s technology transfer program.

Message from Technology Transfer and Intellectual Property Services

Jane C. Moores, Ph.D. assistant Vice Chancellor, Intellectual Property

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4 invent.ucsd.edu

san Diego Campus Contributes to

UC Top 25 InvenTIons

Commercial products developed from UCsD technolo-gies continued to rank in the UC system top 25. in FY2006, four UCsD products represented 21 percent of the total income of the top 25 products for the entire UC system. in FY2007, three UCsD products represented 23 percent of the total income of the top 25 products.

fy2006

4. InterstitialCystitisTherapy(’80) $6,439,0005. EgfReceptorAntibodies(’83) $5,750,0009. FireflyLuciferase(’84) $1,645,00023. HumanCytomegalovirusDiagnostic(’82) $484,000

$14,318,000fy2007

3. EgfReceptorAntibodies(’83) $8,700,0004. InterstitialCystitisTherapy(’80) $7,160,00012. FireflyLuciferase(’84) $1,413,000

$17,273,000

TheSe lIfe SCIenCeS technologies were initially developed in the �980s, yet will continue to contribute to the campus revenues for the next few years. These products are a good example of the lengthy development cycles inherent in life sciences versus the shorter development cycles in engineering and physical sciences technologies. although their development cycles are longer, the potential revenue from much-needed therapeutics can be in the millions of dollars, as exhibited by the oncology product, erbitux®.

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TechTIPS 2006–2007 Biennial Report

UC San Diego 5

NewProductsReachTechnologyMarketsSeveral products based on university tech-nologies reached commercial sales for the first time during fy2006 and fy2007. These products incorporate technologies from physical sciences and life sciences, represent-ing the breadth of university research and demonstrating distinct industry sectors from semiconductor production and research tools, to flavor enhancers.

BlazingNewGroundBlaze DfM, founded in late 2004, continued its growth through financing, merger, and sales. The company began sales in early 2006 and provides software solutions to fabless semicon-ductor companies, integrated device manufac-turers, and silicon foundries. Blaze products give integrated circuit designers greater control over manufacturing variability, improving yield, and shortening time-to-volume production.

In early 2007, Blaze merged with aprio Technologies to complete its electrical DfM technology portfolio. The combination of aprio’s analysis and simulation technol-ogy together with Blaze’s electrical analysis and optimization capabilities provides chip designers with the ability to model, predict, and compensate for systematic variations in advanced silicon process technologies. The merged company retained the Blaze name and headquarters.

Blaze continued to attract financing to fund its growth and closed its Series B round of funding for $�0 million with new and current investors in the first quarter of 2007. Profes-sor andrew kahng (computer science and engineering and electrical and computer engineering), is a founder of the company and developed the licensed technology at the university.

AdvancingResearchProteus Biosciences, based locally in San Diego and founded in 2002, started sales of an antibody to Myosin-VIIa for research pur-poses only. Myosin-VIIa is a member of the myosin molecular motor superfamily that moves along filamentous actin. This protein is expressed primarily in the inner ear, retina and testis. The antibody to Myosin-VIIa is used in mouse models to detect hearing impairment, lack of vestibular function, and progressive retinal degeneration. This research tool was originally developed at UC San Diego by assistant Professor Tama has-son (biological sciences), who is currently at UC los angeles.

NewProductEnhancesFlavorsDuring fy2007, a flavor enhancer and several diagnostic products were introduced into commercial markets. life science and biochemistry technologies incorporated into these products were faster to market since they did not involve long regulatory approval processes and were part of a kit or an added ingredient. one such ingredient was developed by Senomyx, Inc., a locally based company. The first food products that contain Senomyx’s savory flavor ingredients were introduced into commercial markets during fy2007.

Senomyx discovers and develops novel fla-vor ingredients using proprietary taste recep-tor technologies and has collaborations with global packaged food and beverage com-panies. The company is continuing develop-ment of new ingredients using taste sensory targets that include the savory, sweet, salt, bitter, and cooling areas. Professor Charles Zuker (biological sciences/neurobiology) is a founder of the company and developed the licensed technology at UC San Diego.

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AwarepointCorporationSan Diego, Ca

awarepoint provides custom-tailored indoor positioning systems designed to fit the specific client’s needs. The company has developed proven real-time awareness solutions for hospitals that easily merges with the existing operational environments. These systems use exceptionally low-power output resulting in lower costs and reflecting higher standards in safety, while providing streamlined asset tracking. The company was founded with technology developed by Professor anthony acampora (electrical and computer engineering).

EpiphanyBiosciencesSan francisco, Ca http://epiphanybio.com

epiphany Biosciences is developing both therapeutic products and diagnostic tech-nologies that treat or prevent the spread of pathogenic viruses. To support its mission, epiphany has assembled a world-class team of virologists, clinicians, and drug develop-ment experts with extensive pharmaceuti-cal business experience to lead the com-pany forward. The company was founded with technology developed by Professor karl hostetler (medicine).

JacksonvilleTimucuan,LLClas Vegas, nV

Jacksonville Timucuan, a holding company, was formed to explore bundled commu-nications-related technologies developed by university researchers, including UCSD Professors Pamela Cosman, larry larson, Peter asbeck, and Ian Galton (electrical and computer engineering) and Mark Zumberge (Institute for Geophysics and Planetary Physics). The technologies utilize advanced signal-processing techniques that will prove invaluable in tomorrow’s mixed-signal and portable power applications.

NobleMolecules,Inc.San Diego, Ca

noble Molecules identifies new and proprietary uses for approved therapeutic molecules. By doing so, noble simplifies, accelerates, and improves the efficiency of pharmaceutical development. The compa-ny’s founding technology was developed by Professor ajit Varki (medicine).

Psynomics,Inc.la Jolla, Ca https://psynomics.com/about.php

Psynomics Incorporated provides innova-tive tools for the evaluation and treatment

of the biological basis of bipolar disorder and major depression. The company offers Dna-based diagnostic and therapeutic tests to help millions of people suffering from bipolar disorder. Psynomics was founded on the work of UCSD scientists, including Professor John kelsoe (psychiatry).

Quanlight,Inc.San Diego, Ca http://www.quanlight.com/index.html

Quanlight is developing light-emitting diode (leD) technology with increased stability and brightness for use in signage, traffic signal-ing, automotive, and theatrical/architectural lighting markets. Since December 2006, the company raised $4 million in a venture investment from Blackbird Ventures, (ShW)2 enterprises and a small group of private investors. The company was founded with technology developed by Professor Charles Tu (electrical and computer engineering) and former graduate student Dr. Vladimir odnoblyudov.

The company is moving from research and development to wafer production of a new leD chip that offers significant advantages in cost-per-watt and performance over existing leD technology. In addition, the company expects to expand the market

FY2006 and FY2007 Start-ups

In fy2006, The UC San DIeGo CaMPUS ReaCheD an all-TIMe hIGh WITh SeVenTeen STaRT-UP CoMPanIeS formed with university technologies. of the seventeen companies, eight were biotechnology/biomedical with the remainder being engineering/software development companies. eleven of these companies are in California, of which ten are in the San Diego area. In fy2007, nine start-up companies were formed. Seven of these companies were biotechnology/biomedical. of the total start-ups, six were based in California. Below are highlights from select companies.

Technology Transfer and Intellectual Property Services

6 invent.ucsd.edu

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TechTIPS 2006–2007 Biennial Report

UC San Diego 7

by enabling applications not previously economically feasible. Quanlight is led by Ceo neal Senturia, Chairman harvey White, and founder Dr. odnoblyudov.

ScopertaSan Diego, Ca

Scoperta has created a fabless specialty steel technology that utilizes scrap materi-als. The material is exceptionally strong, hard, flexible, and resistant to corrosion and deformation. The company licensed technology developed by Professor ken-neth Vecchio (mechanical and aerospace engineering).

app2youSan Diego, Ca http://app2you.com/site/index.html

app2you™ allows users to create their own custom, hosted, interactive Web applica-tions. app2you requires no programming experience or knowledge of Web technolo-gies. Instead, users simply outline the pages of their application, and app2you does the database and application programming.

app2you’s patent-pending technology originated from the University of California, San Diego web and databases lab of Profes-sor yannis Papakonstantinou. app2you won

a UCSD von liebig Technology Commer-cialization award in May of 2006 to further develop the technology.

TraversaTherapeutics,Inc.la Jolla, Ca http://www.traversathera.com/index.htm

Traversa Therapeutics, Inc., founded in 2006, is a biopharmaceutical company engaged in the discovery, development, and com-mercialization of Rnai delivery technologies. The company strives to rapidly advance short interfering Rna (siRna) platform deliv-ery technologies for use by Rnai therapeu-tic companies in targeting a wide variety of acute, chronic, and infectious human diseases. Traversa is focused on the optimization of this platform delivery technology, as well as advancement of its own therapeutic programs for the treatment of leukemia and glioblastoma.

Based in la Jolla, California, the company licensed technology relating to siRna delivery technology and induction of Rna interference (Rnai) from UC San Diego. This technology was developed by Steven f. Dowdy, Ph.D., a howard hughes Medical Institute investigator, and his research group at UCSD.

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Community Outreach and Partnering Events

SEPT 2005

Regional Technology alliance Venture Roundtable

Schwegman, lundberg, Woessner, & kluth (SlWk) Teleseminar: University and Start-up Company Relations

UC San Diego Technology Roadshow to Taiwan

OCT 2005

Doing Business with UC—newport Beach, Ca

ConneCT® frontiers in Technology

UC San Diego Technology Transfer advisory Committee

ConneCT Technology Transfer Roundtable

licensing executive Society annual Meeting—Phoenix, aZ

NOV 2005

Breakfast with TechTIPS—presentation by Professor Sungho Jin

Innovators Roundtable-Physical Science—presentations by Professors TC hu, Charles Tu, and lu Sham

UC Intellectual Property Managers fall Meeting—Irvine, Ca

UC San Diego Technology Roadshow to China

DEC 2005

ConneCT Most Innovative Product awards Banquet

JAN 2006

Intellectual Property Seminar for the office of Graduate Studies and Research

nanotech Investing—Palm Desert, Ca

FEB 2006

Research expo at Jacobs School of engineering

MAR 2006

Innovators Roundtable-life Sciences—presentations by Professors Deborah Spector and Tony yaksh

association of University Technology Managers annual Meeting—orlando, fl

UC Technology Transfer advisory Committee Meeting

Presentation on Intellectual Property for San Diego Supercomputer Center

UC San Diego Technology Transfer advisory Committee Meeting

UC San Diego Sharecase exhibition and Presentation

APR 2006

Presentation on Intellectual Property for Scripps Institution of oceanography

BIo 2006 annual Conference/exhibition—Chicago, Il

Intellectual Property Seminar for Computer Science and engineering

Presentation to Universities allied for essential Medicines (UaeM)

Presentation at Managing Science and Technology Innovation Workshop (MSTI): Intellectual Property Management at UC San Diego

MAY 2006

UC San Diego Start-up Bootcamp Conference at Calit2

Ventureforth Biotechnology Conference

Innovators Roundtable-Physical Science—presentations by Professors Serge Belongie, Shaya fainman, leonid Butov, and David kriegman

UC San Diego Technology Roadshow—asia

UC Technology Transfer forum—San francisco, Ca

JUNE 2006

San Diego BioPharma Conference 2006

nanoBionexus Meeting

UC San Diego Technology Transfer advisory Committee Meeting

licensing Panel: Turning IP into Cash

Canada-California Strategic Innovation Partnership—Vancouver, BC

JULY 2006

Innovators Roundtable-life Sciences—presentations by yunde Zhao, alan hargens, and Victor nizet

association of University Technology Managers (aUTM) Western Regional Meeting—Boulder, Co

BIoCoM open house

association of Women in Science (aWIS) Meeting

TechTrek, american association of University Women —Science & Math outreach Program for Middle School Girls

Industry/University Cooperative Research Program (IUCRP) Panel

ConneCT Roundtable

AUG 2006

Biotech entrepreneur Roundtable (BeRT) Meeting

licensing executive Society (leS) San Diego Chapter Meeting

SEPT 2006

leS annual Meeting—new york, ny

Tech Coast angels Biomed Trak BeRT Presentation

Division of Biological Sciences Retreat—Warner Springs, Ca

Rady School of Management, Guest lecture on Intellectual Property

Triton Innovation network $50k Biz Plan Competition

Science and Society Interview

BeRT presentation by Richard kornbluth

leS San Diego Chapter—IP, licensing, Spin-outs and Related Business affairs of non-profits

ConneCT life Sciences Venture Roundtable

OCT 2006

UC Technology Transfer advisory Committee (TTaC) Meeting—oakland, Ca

Minneapolis-St. Paul InterCity leadership Presentation

UC San Diego Innovators Showcase at the Birch aquarium at Scripps Institution of oceanography

emerging Company Summit

alternative Career opportunities, the Burnham Institute

TechTIPS Dialogues at Calit2—Disclosing your Innovations

leS San Diego Chapter—Regenerative Medicine

Global ConneCT

Cancer Center Day

TechTIPS has hosted visitors from around the globe. Pictured above are TechTIPS staff members with a delegation from A*Star of Singapore.

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TechTIPS 2006–2007 Biennial Report

UC San Diego 9

NOV 2006

TechTIPS Dialogue at Biological Sciences

Rady School of Management flexMBa, Guest lecture on Technology Transfer

UC San Diego Technology asia Roadshow—korea, Shanghai, Beijing

UC IP Managers fall Meeting—los angeles, Ca

Stem Cell oversight Working Group (SCoWG)

ConneCT Springboard at TechTIPS

TechTIPS Dialogues at Calit2—Patenting your Innovations

DEC 2006

nanoTumor Seminar at the Moores UC San Diego Cancer Center

TechTIPS Dialogue at Calit2—UCoP Patent acknowledgement form

Presentation on Valuation and Due Diligence: forecasting or fortune Telling?

ConneCT Most Innovative Product (MIP) luncheon and awards

Pharma/Biotech IP Due Diligence Summit

BeRT presentation at ConneCT by kenneth Vecchio

JAN 2007

TechTIPS Dialogue at Calit2—Consulting and Start-ups

San Diego Center for Molecular agriculture (SDCMa) agBio Symposium

Stem Cell oversight Working Group (SCoWG)

BeRT presentation at ConneCT

FEB 2007

UC Technology Transfer Directors Meeting

Doing Business with UC Conference—los angeles, Ca. Consortia Presentation

UC Material Transfer agreements (MTa) forum—Berkeley, Ca

Innovators Roundtable-life Sciences— presentations by alexander Groisman, Raffi aroian, and Richard Gallo

San Diego Daily Transcript Roundtable on Intellectual Property

leS San Diego Chapter—Trend in oncology

engMeD—presentation to Potential Industry Partners

MAR 2007

CalBIo Conference

aUTM annual Conference—San francisco, Ca

leS San Diego Chapter—licensing lessons

San Diego Daily Transcript Roundtable on life Sciences

UC San Diego Technology Transfer advisory Committee

APR 2007

office of Technology Transfer (oTT) Special Topics legal Workshop, legal Issues in Research and license agreements—oakland, Ca

UC Technology Transfer forum on nanoTech— San francisco, Ca

nanoBionexus Presentation

Global ConneCT at Calit2—Sir keith o’nions

engMeD—presentation to Potential Industry Partners

MAY 2007

BIo 2007 annual Conference/exhibition—Boston, Ma

UC IP Managers Spring Meeting—oakland, Ca

Panel Discussion—The Technology Transfer operation, Mexican Research Institutions

UC San Diego Technology Roadshow—los angeles, Ca

Innovators Roundtable-Physical Sciences—presentations by Shahrokh yadegari, Gert lanckriet, and David anderson

Panel Discussion—non-faculty Careers in academia for Ph.Ds., UC San Diego Career Services Center

JUNE 2007

Plant Biology Day

The Summit on Intellectual Property for Wireless Technology

Sino-american Biomedical and Pharmaceutical Professionals association (SaBPa) Biopharmaceutical Symposium

UC Copyright Meeting

national association of College and University attorneys (naCUa) Conference Presentation

Triton Innovation network $50k Business Plan Competition—final Presentation

NOV 2005Germany Delegation—hanover, Germany

kIPa Delegation—South korea

DEC 2005keio University—Tokyo, Japan

Science attaché—france

JAN 2006Singapore Delegation

MAR 2006kyoto Research Park—Japan

APR 2006korea Institute of Science

MAY 2006australian Delegation

JUN 2006Beijing Pharmaceutical Group

Science and Technology, British Consulate

Minneapolis-St. Paul leadership Delegation

Monash University—Victoria, australia

JULY 2006national Taiwan University hospital—Dr. Wk Chan

Samsung electronics—Paul kim

AUG 2006Consulate General of france—Peggy Rematier, Deputy Scientific attache

naples, Italy—Dr. emanuele fiore

Presentation to korean Delegation for Global ConneCT

SEPT 2006University of British Columbia—Caroline Bruce

kRf and korean Technology licensing Delegation

okinawa Delegation

OCT 2006Sacramento Chamber of Commerce

NOV 2006Universities allied for essential Medicine (UaeM)

korean Government Delegation

UC los angeles, aCe Senior fellow

kyoto Comparative law Center (kClC)

DEC 2006Sanyo Corporation

FEB 2007australian Delegation

SeT2 directors

MAR 2007Bend Research and Pfizer

APR 2007Greater austin Chamber of Commerce

University of helsinki—finland

MAY 2007University of otago—Dunedin, nZ, Geoff White, Deputy VC for Research

Universities allied for essential Medicine (UaeM)

JUNE 2007Presentation—Global ConneCT/korean Delegation—University Interaction with Industry

Thailand Delegation

Welcome Our Visitors

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�0 invent.ucsd.edu

Financials

A.IncomeUC San Diego intellectual property income in fy2006

was approximately $26.7� million. Income included

nearly $22 million in license fees and royalties from

inventions, over $300,000 in license fees and royalties

from copyrights, over $300,000 in fees from the transfer

of tangible research materials, and over $4.2 million in

patent cost reimbursement. In fy2007, intellectual prop-

erty income remained flat at approximately $26.3 million.

This income included $2�.4 million in license fees and

royalties from inventions, over $200,000 in license fees

and royalties from copyrights, nearly $330,000 in fees

from the transfer of tangible research materials, and ap-

proximately $4.� million in patent cost reimbursement.

for a breakdown of total income by category, please

refer to the appendix.

� included one-time payment of $3 million

B.MandatoryDistributionsTechTIPS distributed approximately $��.7 million in

fy2006, and distributed approximately $�4 million

in fy2007. Distributions were made to inventors, joint

titleholders, participating academic units for research

support, and the UC General fund in accordance with

the UC systemwide patent policy and UCSD campus

guidelines. Invention and copyright income distributions

are based on income received in the prior fiscal year (ac-

crual basis). Material Transfer agreements (MTa) income

distribution is based on income received in the same

fiscal year (cash basis).

C.ExpensesUC San Diego’s technology transfer program incurred

expenses of $�3.2 million in fy2006. Included in this

total are approximately $2.7 million for UCSD office

operations, $878,000 for systemwide office operations

and assessments, and $6.� million in patent prosecution

costs. The following year, incurred expenses decreased to

$�2.3 million in fy2007. The decrease can be attributed

to lower UCoP and office of Technology Transfer

assessments as a result of completed decentralization. a

detailed breakdown of total expenses by category can

be found in the appendix.

D.ResearchImpactUC San Diego’s technology transfer program continued

to have a positive impact on research programs.

TechTIPS distributed license income to support research

by providing incentives in the form of research share

and inventor/author share of the net income for faculty

retention and recruitment. In addition to the mandatory

distributions of income under UC patent policy and

UCSD campus guidelines, TechTIPS negotiated ad-

ditional funding for research in its license agreements,

whenever appropriate. In fy2006, the total research

impact was estimated to be approximately $8.5 million.

In fy 2007, the total research impact was estimated to

be approximately $��.5 million. This impact comprised

distributions to researchers/authors, research laborato-

ries, academic departments, nonprofit co-owners of IP

and sponsored research pledges as a result of licenses

and matching grants.

tAbLe: mandatory Distributions of iP management income FY1995–2007

1995* 1996* 1997* 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 TOTAL

Inventor/ author Share

$643,705 $848,773 $907,��2 $�,�7�,430 $2,5�2,878 $�,597,695 $2,�54,60� $2,097,659 $4,054,355 $2,654,288 $3,726,954 $6,�9�,680 $8,667,449 $37,228,579

Joint Titleholders Share

$�3,�78 $��,4�3 $46,882 $38,359 $94,22� $59,635 $�96,770 $633,082 $303,7�9 $295,220 $76,694 $36�,940 $�27,447 $2,258,560

Research labs/haU#/Dept. Share

- - - $45�,008 $345,74� $980,352 $928,6�4 $�,990,384 $�,270,694 $�,�25,692 $�,2�4,848 $�,746,753 $2,500,539 $�2,554,625

UC General fund Share †

$252,930 $243,952 $299,023 $�,08�,503 $235,872 $730,�40 ($4��,62�) $�,5�9,�49 ($�,2�8,547) $�,007,43� $2,656,722 $3,382,248 $2,6��,987 $�2,390,789

Total Distributions $909,813 $1,104,138 $1,253,017 $2,742,300 $3,188,712 $3,367,822 $2,868,364 $6,240,274 $4,410,221 $5,082,631 $7,675,218 $11,682,621 $13,907,422 $64,432,553

* InVenTIonS only# home academic Unit † fy0� and fy03 shows credit due to extraordinary legal expenses; formerly called State General fund

$5.2million

$8.5million

$11.5million

200720062005

$6.8million

$4.3million

$8.3million

$6.6million

200320022001

$5.1million

20042000

$5.9million

$6.4million

$6.3million

$4.9million

199819971996

$1.6million

19991995

estimated research impact

95 0696 97 98 99 00 01 02 03 04 05

total income from intellectual Property management(in $ millions)

3.0

26.7

3.7 4.35.3

6.1

9.18.4

17.0

10.7

15.0

21.6

07

26.3

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TechTIPS 2006–2007 Biennial Report

UC San Diego ��

Activities

IntellectualPropertyDisclosuresThe number of invention and copyright disclosures

continued to increase during fy2006 to 345 disclosures,

compared to 334 disclosures in fy2005. Disclosures

increased to 373 in fy2007. as the first step in the IP

management process, the increase in disclosure num-

bers serve as a positive indicator for future activity.

AgreementsTechTIPS agreement activity increased to 747 agree-

ments in fy2006, compared to 7�3 agreements in

fy2005. In fy2007, total agreements increased to 758.

The totals comprised licenses, options, letters of intent

(loI), outgoing material transfer agreements (MTa),

confidentiality, and other administrative agreements.

license agreements are further broken out into those for

inventions and those for copyrights/trademarks.

IntellectualPropertyProtectionUCSD’s technology transfer program continues to

achieve high numbers for patent prosecution and

protection. In fy2006, 27� patents were filed—of which

�82 were U.S. provisional or nonprovisional filings and

the remaining 89 were foreign applications. We con-

tinued to increase our patent portfolio with �92 issued

patents—of these, 44 were U.S. patents and �48 were

foreign patents.

In fy2007, 267 patents were filed—of which 207

were U.S. provisional or nonprovisional filings. During the

same year, �26 patents were issued, of which 64 were

U.S. patents, and 62 were foreign patents.

inventions

76Copyrights

4

1995

inventions

137Copyrights

2

1996

inventions

139Copyrights

11

1997

inventions

161Copyrights

15

1998

inventions

194Copyrights

41

2000

inventions

265Copyrights

16

2001

inventions

255Copyrights

56

2002

inventions

294Copyrights

28

2003

inventions

290Copyrights

44

2005

inventions

310Copyrights

35

2006

inventions

333Copyrights

40

2007

intellectual Property Disclosures FY1995–2007

tech transfer Agreements

0696 97 98 99 00 01 02 03 04 05

187

747

234 236 242

489576 592 626

699 713

tAbLe: Patent Activities FY1995–2007

Filings 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007

U.S. Provisional - - - - 60 55 74 75 �27 �44 �33 �47 �42

U.S. nonprovisional �07 70 94 96 87 87 76 86 45 44 39 35 65

International - 4 �� 40 37 22 40 4� 69 94 67 89 60

TOTAL FILED 107 74 105 136 184 164 190 202 241 282 239 271 267

Patents Issued

U.S. Issued �4 27 30 36 40 58 59 42 5� 50 60 44 64

foreign Issued � � - 4� 5� 33 36 39 69 79 87 �48 62

TOTAL ISSUED 15 28 30 77 91 91 95 81 120 129 147 192 126

License Agreements for inventions and Copyrights

95

6

0696 97 98 99 00 01 02 03 04 05

21

54

23 25

24

41 34

28

23

41

49

Inventions

Copyrights/Trademarks

5 1 173 2 19 6 12 23 18 15 22

inventions

200Copyrights

16

1999

inventions

288Copyrights

26

2004

07

56

29

07

758

95

250

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�2 invent.ucsd.edu

Appendix

INCOME

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 TOTAL

Invention $2,204,002 $2,389,�28 $2,90�,369 $3,057,487 $4,042,9�9 $5,476,522 $5,627,�39 $7,240,086 $6,367,907 $��,472,540 $�5,496,2�4 $2�,842,293 $2�,423,345 $�09,540,95�

Copyright - - - $��,649 $74,223 $83,58� $46,083 $202,503 $�56,608 $3�4,268 $2�4,4�8 $3��,324 $2�9,023 $�,633,680

TangibleResearchMaterials

- - - - - $647,40� $595,253 $�,�22,889 $474,3�� $405,074 $578,3�5 $309,756 $328,673 $4,46�,672

legal CostReimbursement

$76�,687 $�,287,424 $�,377,230 $2,259,994 $2,028,760 $2,848,046 $2,032,033 $2,898,996 $3,677,680 $2,896,�68 $5,396,047 $4,234,046 $4,095,860 $35,793,97�

extraordinary Income †

- - - $3,000,000 - - $55,779 $5,552,353 - - - $�,��9 $�93,40� $8,802,652

Total Income $2,965,689 $3,676,552 $4,278,599 $8,329,130 $6,145,902 $9,055,550 $8,356,287 $17,016,827 $10,676,506 $15,088,050 $21,684,994 $26,698,538 $26,260,302 $160,232,926

EXPENSE

1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 TOTAL

Patent Prosecution

$�,297,086 $�,679,763 $2,092,643 $2,750,577 $2,�54,597 $3,503,079 $3,�04,498 $3,832,578 $4,028,957 $4,644,92� $6,�32,46� $6,�6�,363 $6,336,256 $47,7�8,779

Copyright - - - $5,000 $2,500 $7,500 $5,000 $937 $2,90� $60 $3,630 $�85 $270 $27,983

Campus operations

$380,773 $5�9,248 $699,279 $689,296 $892,006 $�,2�3,967 $�,386,222 $�,696,395 $�,98�,436 $2,263,30� $2,272,05� $2,69�,��6 $2,732,�94 $�9,4�7,284

UCoP & oTT assessment

$473,2�5 $426,70� $5�3,�3� $650,648 $472,203 $438,�7� $602,743 $862,383 $90�,692 $877,272 $892,256 $878,79� $460,662 $8,449,868

extraordinary expenses*

- $�63,795 $35,924 $40,865 $397,�90 $220,594 $3,9�5,960 $2,992,5�4 $6,566,8�6 $2,789,449 $257,504 $57,3�4 $205,2�7 $�7,643,�42

UC General fund**

$252,930 $243,952 $299,023 $�,08�,503 $235,872 $730,�40 ($4��,62�) $�,5�9,�49 ($�,2�8,547) $�,007,43� $2,656,722 $3,382,248 $2,6��,987 $�2,390,789

Total Expense $2,404,004 $3,033,459 $3,640,000 $5,217,889 $4,154,368 $6,113,451 $8,602,802 $10,903,956 $12,263,255 $11,582,434 $12,214,624 $13,171,017 $12,346,586 $105,647,845

NET INCOME $561,685 $643,093 $638,599 $3,111,241 $1,991,534 $2,942,099 ($246,515) $6,112,871 ($1,586,749) $3,505,616 $9,470,370 $13,527,521 $13,913,716 54,585,081

† extraordinary income includes nonrecurring items such as legal settlements and/or one-time payments. * extraordinary expenses includes unbudgeted expenses for litigation and settlement. ** UC General fund was previously called State General fund.

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TechTIPS 2006–2007 Biennial Report

UC San Diego �3

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