technology transfer from the university of oxford

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Technology Transfer from the University of Oxford

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Technology Transfer from the University of Oxford

Las Relaciones Universidad – Empresas:Un Nuevo Paradigma

isis-innovation.com

Knowledge Based Economy

• Every country in the world wishes to develop the Knowledge Based

Economy. 

• The question is asked: • Where is the Knowledge? 

• And the answer in part is inside the universities, and research institutes, and hospitals. 

• And the question then becomes: • How do we transfer the knowledge out from the research base into

industry to create innovation? 

isis-innovation.com

Towers

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Making Connections & Doing Business

University entrepreneurial

culture

Industry, Business & Professional environment

University technology transfer resource

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Chalk and Cheese

• Universities and Businesses are very different• A university is not trying to be like a company• A company is not trying to be like a university • Why should Universities want to engage with Businesses?• Why should Business want to engage with University?

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University & Business Interactions

• Educated workforce

• Advisory Boards

• Lectures

• Exchanges

• Collaborative Research

• Contract Research

• Donations

• Consulting

• Licensing technology

• Spin-out company formation

• Entrepreneurship

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Oxford University

• Oxford University is the oldest university in the English-speaking world (founded c.1188)

• A leader in learning, teaching and research

• 26 British Prime Ministers educated at Oxford

• Including current Prime Minister David Cameron

• Royal Society founded from Oxford in 1640

• 47 Nobel prize winners

isis-innovation.com

Isis Innovation Ltd

Oxford Technology TransferIP, Patents, Licences, Spin-outs, Material Sales, Outcome Questionnaires, Seed Funds, Isis Angels Network, Isis Software Incubator, Oxford University Hospitals NHS Trust

Oxford ExpertiseConsulting, Services

@isisinnovation

A profitable company 100% owned by the University of Oxford

Isis Consulting Business Technology Transfer and Innovation Management

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Isis Innovation, year-ending March 2013

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Start-UpsSpin-Outs

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Isis Innovation, year-ending March 2013

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2006 2007 2008 2009 2010 2011 2012 2013

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Isis helps researchers who wish to commercialise the results of their research

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Technology Transfer Group (38) Linda Naylor

Isis Innovation TeamOxford University Consulting(7)

Andrew GoffProject Managers

Susan ClarkGurinder PunnDr Josef WalkerKerry AntcliffeAdministrators

Magda BezdekovaSelina Woodcock

Dr Adam Stoten

Dr Carolyn PorterDr Alex Marshall

Dr Christine WhyteDr Ruth Barrett

Dr Richard ReschenDr Louis Pymar

Dr Paul AshleyDr Angela Calvert

Andy SelfDr Sarah Deakin

Dr Matthew CarpenterDr Nikolaos Chalkias

Dr Brijesh Roy

Medical SciencesDr Linda Maxwell

Evert Geurtsen

Rakesh RoshanDr Jon Carr

Dr Bharti RanavayaDr Andy RobertsonDr Andrew Bowen

Dr Richard HollidayChim Chu

Dr Fred KempDr Mark Gostock

Dr Weng Sie Wong

Team Leader VacancyDr David Churchman

Dr Jamie FergusonRoy Azoulay

Dr Manjari Chandran-Ramesh

Staff & Associates: 87 MBAs: 14 PhDs: 40

Managing DirectorTom Hockaday

Business Support (18)

Central AdministrationJenny BaileyPhilip Priest

Nissar MohammedRicky AllainIsabel Lavis

HRCarolyn Hall

Alex AllanViv Parry

MarketingSimon GrayRenate Krelle

Dr Chandra RamanujanDr Fiona StoryBarney Cullum

FinanceJaneen WilsonGemma Allnutt

Amanda Thornton

LegalParesh Jasani

Technology Transfer Teams

Isis Enterprise (24)Consultants

Dr David Baghurst (Hong Kong) Ya-hsin Shen (Hong Kong)

Dr Jimmy Wang (Hong Kong) Dr Wenming JiRenchen Liu

Kenji Aiba (AC-Japan)Xiaowei Hu (AC-China)Dr Costas Chryssou

Dr Sarah BondDr Andrew BarberDr Mireya McKee

Dr Steve Cleverley Elena Andonova

Dr Alexandra BushDr Sarah Macnaughton

Gaurav MisraBruno Reynolds

Eva Baltar, Manuel Fuertes (AC-Spain)Dr Tim Hart (AC-UK)

Dr Chris MoodyDr Salvador Venegas (AC-Mexico)

OperationsShelagh Harrison, Chloë Cairns

Operations Patent & Licence Dr Mairi Gibbs Steven Bayliss

Zuzana Weberova Seed Investment Kate Spanchak

Andrea Alunni

Administration Kristin

Hayes

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Academic axis£ -> Research

3D – Spin-out

2D – Licence, Consulting

Isis Innovation StaffActing as Multi-dimensional Intermediaries

Investor axis£ -> £££

Commercial axisResearch -> £

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Intermediaries – 4th DimensionIntermediaries - International

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Intermediaries – 4th Dimension

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Isis Impacts

• The impact of Isis activities

is seen through the take-up

of new technologies and

ideas that form the basis

for new products and

services.

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Publications

Isis on Twitter

LinkedIn

Facebook

@isisinnovation

Isis E-News & IAN E-News

Chinese Isis E-News

isis-innovation.com

Oxford University Technology Spin-outs (post 2000)

2000 7Third Phase, Mindweavers, Oxford BioSignals, Oxford BioSensors, TolerRx, OXIVA, Pharma DM

2001 7OxLoc, Oxford Bee Co, Oxford Ancestors, Novarc, Oxford ArchDigital, Natural Motion, Inhibox

2002 9Pharminox, Minervation, Oxford Biomaterials(Spinox), Zyentia, Oxitec, Oxford Immunotec, Oxford Risk, GlycoForm, BioAnalab

2003 4 Summit(Vastox)* , ReOx, Riotech, OCSI

2004 4 Avacta(OMD)* , G-Nostics, Surface Therapeutics, EKB Technology

2005 5Oxford Nanopore Technologies, Oxford RF Sensors, Oxbridge Pulsars, Celleron, Oxford Catalysts*

2006 7TDeltaS, Oxford Medistress, Particle Therapeutic, Aurox, Oxford Advanced Surfaces* , Cytox, OxTox

2007 4 Eykona Technologies, Clinox, Oxford Biodynamics, Crysalin

2008 4 Semmle, Oxford-Emergent TB Consortium, Navetas(ISE), Organox

2009 3 Oxford Financial Computing, Zyoxel, Oxford Yasa Motors

2010 4 OxEms, Kepler Energy, IXO, Oxford PhotoVoltaic

2011 5 Oxyntix, Oxtex, Oxford Multi Spectral, Oxford Imaging Detectors, OCB

2012 4 Intelligent Ultrasound, OxEHealth, Oxford Vacmedix, Run3D

2013 [1] Perspectum Diagnostics

Total external investment to date in 68 spin-outs since 2000: £506m £46m 1st round Seed/Business Angels – £460m follow-on Investment Capital

TT

* Stock exchange listing

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Spin-outs – The Players

Shareholder, Director, Consultant

Isis - licence, University shareholding, director (OSEM)

Lawyers

Accountants

Shareholder, Director

CEO, Shareholder

Bankers

Ad

vis

ers

Sh

are

hold

ers

I

N

V

E

S

T

M

E

N

T

FounderResearchers

Isis Technology Transfer Manager

Lawyers

Accountants

Manager (1)Manager (2)?

Investor (1)Investor (2) ?

Bankers

Time

TT

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Investment Sources

Oxford University Challenge Seed Fund• Launched with £4m in 1999• University provided £1m; HM Treasury, Wellcome, Gatsby £3m• £5.7m invested in 102 projects – development, seed equity• Resulting in Equity stakes in 31 spin-outs, 4 completed licensing

deals & 33 active technology projects. These 31 spin-outs have attracted £80m seed/venture investment

Oxford Invention Fund• Donations to the University of Oxford as part of Oxford Thinking,

the University’s overall fund raising Campaign• Invest in development of new technologies and innovation from

OxfordIsis Angels Network• Business Angels, Seed/Venture Capital• 100 members• Events, No Charges

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Isis Software Incubator, established in 2010

• Support for early-stage software ventures from Oxford University

• Assists the creation and development of a software business opportunity, whether or not a company has yet been incorporated

• Isis provides commercial mentoring, negotiation support, services, desk space, access to business networks

• Projects that have a credible business concept and need:

• Substantial work to develop IP and build a realistic commercial prospect

• With entrepreneurial founders

• But do not need patents, investors, full-time management

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Investment Gap

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Piers & Bridges

Business is over here !

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Building Bridges

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Vision for Isis

• Technology

• Innovation

• For People

• From Oxford and elsewhere

• Successful exploitation of new ideas

• Health & Wealth of Society

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Conclusions – How Isis Works

• Universities• Technology Transfer is a good thing

• Part of University purpose; may make money for University and researchers

• It does not happen on its own• You need to invest resources in People, Patent budget, Proof-of-Concept

• You need a policy framework• Who owns the inventions; who shares the rewards

• It takes a long time … So start and do not stop.

• Business• Access to technologies, resources and expertise• Help understand universities• Help your business innovate

• Investors• Source of investment opportunities• Home for entrepreneurs

• Government• Stimulates innovation and enterprise• Improves society

Elements

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Elements

Research BaseUniversities

Research InstitutesResearch Hospitals

GovernmentTax

Grants

BusinessIndustryFinance

Commerce

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Elements – Research Base

• Supportive Vice-Chancellor, Rector, Provost, Director• & Senior Researchers

• Research Activity• High volume & quality

• Researcher engagement

• University Policies• IP Ownership / Revenue sharing / Spin-outs• Disputes

• Research Services Office• Manage relationship with Research funders

• Access to Proof of Concept / Seed funds• To accelerate technology transfer

• Technology Transfer Office• Adequately resourced

• Policy• Patent Budget• People• Proof of Concept

• Leadership• Stories• Resources

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Nothing beats a good story

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Publications

Isis on Twitter

LinkedIn

Facebook

@isisinnovation

Isis E-News & IAN E-News

Chinese Isis E-News

isis-innovation.com

Elements – Business & Finance

• Business Networks

• Innovative Technology companies• As Licensees

• Business Angels

• Seed & Venture Capital

• Entrepreneurs

• Professional Advisers• Banks / Accountants / Lawyers / Property

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Innovation Funnel

Professor Henry Chesbrough

Open Innovation: The New Imperative for Creating and Profiting from Technology (HBS Press, 2003).

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Oxford incubators & science parks

Isis Software Incubator

Oxford Centre for Innovation Oxford Magnet

Begbroke Science Park

Oxford Science Park

Oxford Entrepreneurs

Incubator

Oxford Low Carbon Hub

Oxford Hub

Milton Park

Oxford BioEscalator

Harwell - European Space Agency's Business

Incubation Centre  

Science Vale Enterprise Zone

Source: Google Maps

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Oxford Science Parks

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Oxford Entrepreneurs Incubation Centre

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Elements - Government

• Tax incentives• SME Benefits• CGT & Income Tax• Tax credits & Tax relief• ‘Patent Box’

• Grant programmes• Technology Transfer capacity, proof-of-concept• Businesses

• Legislative framework• Intellectual Property• Company law

• Public procurement

• Support & Clarity & Consistency

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Elements – A fourth area ?

• Non Governmental Organisations

• Charities

• Foundations

• Not-for-Profits

• Social Enterprise

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Elements

Research BaseUniversities

Research InstitutesResearch Hospitals

GovernmentTax

Grants

BusinessIndustryFinance

Commerce

isis-innovation.com

Elements

Government

BusinessResearch

Base

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The Innovation System

Recruitment, head-hunters

Angel Networks

Students

Angel Investors

Investment Funds

Accountants

Bankers

Lawyers

Technology Transfer

organisations

University Researchers

Commercial property managers

Journalists

Consultants

Public Relations

Local Government

Hospitals

Government Labs

Research Institutes

Members of Parliament

Incubators

Business networks

Science ParksOther

universities

Industry

Technology companies

Business

Start-ups

‘City deal’

Local Enterprise Partnership

isis-innovation.com

[Isis] helps researchers - and students - who wish to commercialise the results of their research

isis-innovation.com

Themes …

• Impact• Change• Benefits• Academic view of relationships with industry• TT is smaller part of a bigger picture

• Specialisation• Vanity subjects … ?

• Convergence• Technology Transfer• Entrepreneurship – Social & Business• Distributed

• Young people

isis-innovation.com

www.isis-innovation.com

Isis Innovation Ltd, Ewert House, Ewert Place, Summertown, Oxford OX2 7SGT 01865 280830 F 01865 280831 E [email protected]

Register to receive Isis E-News at: www.isis-innovation.com/news/enews Follow us @IsisInnovation