technology transfer roll no.18,10
TRANSCRIPT
ECHNOLOGY RANSFER T
JAITESH SINGH (10)
RUHI GUPTA(18)
INTRODUCTION
It is a process which is mainly concerned with the transfer of technology from the research areas to the “Production and Quality Assurance” environment .
The Process by which existing knowledge , facilities or capabilities developed under R & D funding are utilized to fulfill public and private need.
“Technology Transfer” includes a range of formal & informal cooperation between technology developers and technology seekers.
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Varied Roles
IDEA
Research
Development
Production
Manufacturing
Distribution
Start-upFirms
R & DFirms
LargerCompanies
Universities
ResearchInstitutes
MARKET
Ways “Technology” is Transferred
Consulting
Graduating students (“moving heads”)
Faculty moving on (“moving heads”)
Collaborative research
Patenting and licensing
Service and outreach (“extension”)
Spin-off companies
Technology Transfer Agents
R&D Units• Universities• Public Research Centers• Technology Institutes(institutions, labs etc)
Companies• Supplier of technologyand R&D to third parties• Spin-off, start-ups• Large R&D department• Competitors, suppliers…(technological alliances)
TYPES OF TECHNOLOGY
1) EMERGING TECHNOLOGY- is an innovative technology that currently is undergoing bench scale testing, in which a small version of the technology is tested in a laboratory.
2) INNOVATIVE TECHNOLOGY- is a technology that has been field tested and applied to a hazardous waste problem at a site, but lack a long history of full-scale use.
3) ESTABLISHED TECHNOLOGY- is a technology for which cost and performance information is readily only after a technology has been used at many different sites and the result fully documented is that technology considered established.
APPROPRIATE TECHNOLOGY
Technology that suits one country may not be suitable to other countries. As such the countries develop appropriate technologies which suit their topographical conditions, climatic conditions ,soil conditions ,conditions of infrastructure ,etc.
FOR EXAMPLE Japanese automobile industry and Korean automobile industry design different types of cars which suit the Indian roads.
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CONSTITUENTS OF TECHNOLOGY TRANSFER PROCESS
Technology Transfer Technology Promotion Technology Deployment Technology innovation Technology Development Technology Research Technology AssessmentTechnology Information and Communication Technology Investment Technology Collaboration Technology Commercialization
PROMOTION
INNOVATION
RESEARCH & DEVELOPMENT
ASSESSMENTINFORMATION &
COMMUNICATION
INVESTMENT
COLLABORATION
COMMERCIALIZATION
TECHNOLOGY TRANSFER PROCESS
Proper Research
Paper work
Pricing
Publicity
Partnership
People’s
Acceptance
CONTENT OF TECHNOLOGY TRANSFER
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Proper Research – By proper research we mean firstly that in which the result are reproducible and issues such as scale up, stability etc and other practical now has been addressed, also that in which problem were taken up in first place.
Proper work- This refer to institutional and guidelines regarding IP Protection licensing modalities etc. which must be in place beforehand. In the absence of these, decision get delayed, lack of fairness in decision e.g. case of X institute, which came up with good technology but since no guidance were there, kept running around for two years and then gave up.
Pricing – most difficult and critical area of Transfer of technology. - Too high price can put off buyer, leaving the technology unsold. - Too price a result in revenue loss. - There are basically two model regarding pricing1) Price charged for a technology should depend upon
market force i.e. impact of the technology irrespective of amount spent on developing it.
2) Price charged should include all expenses involved in developing it.
Publicity – It is important to identify and then approach buyer i.e. adopt targeted Publicity and not blanket publicity. Specific journal, website, letters to manufacturer, personal selective visit etc. are some common approach which help in locating buyer.
Partnership – this means working along with industry. Industry takes it up, manufacturer and makes available to society. Partnership are important to ensure your technology is successfully adopted simply conveying the details may not be sufficient.
People’s Acceptance – It is no use trying to develop a technology which people will not accept e.g. due to religious reason/social concern etc. genetically modified food, irradiated vegetables processed beef in India, improved capsule made of non-vegetarian material.
LIST OF INSTITUTE IN INDIA ASSISSTING IN TECHNOLOGY TRANSFER
Asia pacific centre for Transfer of technology ( APCTT) Technology Bureau for small enterprises ( TBSE)
National Research & Development Corporation
Foundation for Innovation and Technology Transfer
Process technologist
• central focus for transfer activities• collates documentation from donor site• perform initial assessment of transferred project for a) feasibility b) compatibility with site capabilities c) establishes resource requirements
Representative Review documentation to determine compliance with Marketing authorization (MA) Review analytical methods with QC to determine capability, equipment training requirements.Initiate conversion of donor site documentation into local system/formatInitiate or confirm regulatory requirement, e.g. change to manufacturing license , variations to MA if process changes needed, etc.
Proposed Team Member and Their Responsibilities
Production representative
Review process instructions (with process technologist) to confirm capacity/ capability Considers any safety implication e.g. solvents, toxic, sanitizing materialsConsider impact on local standard operating procedures (SOPs)Consider training requirement of supervisors/ operator
Engineering representative
Review (with production representative) equipment requirement Initiate required engineering modification/ change/ part purchase.Review preventative maintenance/ calibration impact, e.g. use of more aggressive ingredients: more temperature sensitive process, and modifies accordingly.
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1) Coordinate- Coordinating between technology users and developer, between researcher and manufacturers is important element of technology transfer.
2) Nurture- A main ingredient for moving technology from a research laboratory to a new business enterprises successfully in an environment that is supportive for entrepreneurship.
3) LINK- Cataloging resources related to business enterprises & connecting would be entrepreneurship / researcher and other
technology developers to outside group & organization which can help in the process of starting new product, companies etc.
such linkage provide referrals for individual business counseling, sources of financing.
FUNCTION OF TECHNOLOGY TRANSFER TEAM
FACTOR AFFECTING TECHNOLOGY TRANSFER
TIPS Method ( Technology implementation Potential for Success)
Communication Factor TIPS
Financial Factor TIPS
External Factor TIPS
Human Factor TIPS
Corporate Factor TIPS
Technology Factor TIPS
Production master formula
Manufacturing instruction
Dispensing instruction
Analytical methods
Previous process validation
Stability reports
Exicipient specification and source
Active specification and source
TECNOLOGY TRANSFERCHECKLIST
Primary packaging material specification and source
Packaging instruction
Customer complaints
Process deviation file
Analytical deviation file
Reject /Rework file
Specimen manufacturing batch record
Specimen Cartons, Labels, Leaflets
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EXAMPLES OF TECHNOLOGY TRANSFER
CHINA
L – Phenyl alanineBy enzyme method
(Ref : APC – 4041 – TOF)
# Chinese company offer technology for the production of L- Phenyl alanine by the enzyme method.
Area of Application # Food industryAdvantage- Low input Advanced process No environmental contamination Clear production
Stage of development commercialized
Economic data Total project cost 4 million Equipment 1.38million
Transfer form Known how, consultancy, equipment, training
Target country world wide
Language English
A Novel, Non-infringing Process for the manufacture of levobupivacaine
NIPER, mohali offer a non-infringing process for the manufacturer of an improved widely used local anesthetic, levobupivacaine.
The process uses a chiral catalyst for asymmetric synthesis of the product.
Area of Application Local anesthetic product widely used in hospital in surgical procedure.
Advantage of technology Uses easily available raw material Faster compared to existing process as no resolution involved. Cheaper as use of expensive resolving agent is altogether eliminated Non-infringing new processStage of Development Process at laboratory scale Scale up to be done Facilities for scale up exist at institute ( pilot plant available)
Economic Data Product name – Chirocane, ( approved clinically) No manufacturer in India till date Transfer form Technology licensing and Known how
PROBLEM IN TECHNOLOGY TRANSFER
India pushes for tech. transfer at Durban climate talksIndia has proposed that the climate talks in Durban should be refocused onto technology transfer, equity and trade barriers.According to the Delhi-based non-governmental organization Centre for Science and Environment, proposals were made at the UN Climate Change Conference in Cancun, Mexico, last year, to set up a technology executive committee and a climate technology centre and network.But the final agreement does not mention intellectual property rights, “ which means patented technologies cannot be accessed“.
Manufacturer of Pharmaceutical Raw Materials,
Pharmacopoeial Fine Chemicals,
Active Nutraceuticals,
Laboratory Reagents (Bulk)
(LR /AR/ ACS/FCC)
Nutraceuticals
Pharmacopoeial Fine Chemicals
EDTA Fine Chemicals
Phosphates Fine Chemicals
Azithromycin APIs
Sorbic Acid & Potassium Sorbate
Potassium Phthalimide
Citrate Fine Chemicals
Inositol & Inositol Nicotinate
TECHNOLOGIES TRANSFER : Bimal pharma PVT. Ltd. A team of technically highly qualified technocrats in the pharmaceutical field, having experience of manufacturing of API, intermediates, pharma fine chemicals and pharma formulations, for more than 25 years, they offer complete “turn-key” project services including detailed engineering, complete demonstration of manufacturing processes of all apis; intermediates for apis; pharma fine chemicals and pharma formulations. They are also experts in supplying the best quality intermediates / penultimate stages, along with technologies to make final apis to suit your US FDA / WHO-GMP approved manufacturing units for different countries.
hank you…
T