ted w. simon, ph.d., dabt · ted simon, ph.d., dabt page 2 of 19 january 2018 • simon tw, zhu y,...

January2018

TedW.Simon,Ph.D.,DABT Contact4184JohnstonRoad email:[email protected] Winston,GAUSA30187 website:http://www.tedsimon-toxicology.com

mobile:+01(770)359-9807

SummaryAwardwinningtoxicologistandscientist.10+years’experienceasatoxicologistemployedbytheEnvironmentalProtectionAgency(EPA).10+yearsconsultingandexpertwitnessexperience.ServedasEPA’sseniortoxicologistinthewastemanagementdivisionworkingonriskandsoilcleanup.Wellpublished,includingauthoroftextbookontoxicologyandenvironmentalriskassessmentandareferenceworkonpesticides.Experiencedexpertwitnessonissuesincludingenvironmentalrisk,Illegaldrugs,pharmaceuticals,alcoholandmarijuana,DUI,accidentalpoisoning,andintellectualproperty.Expertiseintoxicology,riskassessment,mathematicalmodeling,statistics,neuroscience,andenvironmental/ecologicalhealthissues.Interestandexpertiseintheeffectsandtestingofalcohol,marijuanaandpharmaceuticals,perfluorinatedchemicals,arsenic,chromium,benzeneandothersolvents.Extensivenationalandinternationalpublicspeakingexperience.15+yearsteachingexperience.

ProfessionalCertification1994- DiplomateoftheAmericanBoardofToxicology(DABT)

EmploymentHistory2004-present Principal,TedSimon,LLC,Winston,GA2006-present AdjunctProfessor,EnvironmentalHealthScience,CollegeofPublicHealth,Universityof

Georgia,Athens,GA1996-2006 Toxicologist,USEnvironmentalProtectionAgency,Region4,Atlanta,GA2003 Instructor,DepartmentofBiology,GeorgiaStateUniversity,Atlanta,GA2001-present Instructor,DepartmentofEnvironmentalHealthScience,UniversityofGeorgia,Athens,GA1996 EnvironmentalHealthScientist,AgencyforToxicSubstancesandDiseaseRegistry/Centersfor

DiseaseControl,Atlanta,GA1994-1996 Toxicologist,USEnvironmentalProtectionAgency,Region4,Atlanta,GA1993-1994 ProjectScientist,ManTechEnvironmentalInc.,USEPARegion4,Atlanta,GA1993 AssistantProfessorofBiology,LifeCollege,Marietta,GA1991-1993 GeorgiaStateUniversity,PostdoctoralResearchAssociate,Atlanta,GA1989-1991 EmoryUniversity,PostdoctoralResearchFellow,Atlanta,GA1982-1988 GeorgiaStateUniversity,Research/TeachingAssistant,Atlanta,GA

PublicationsBOOKS • AndersonSA,SimonTW.(2018)DefendingPesticidesinLitigation2018Edition.ThompsonReuters,ISBN:978-

0-314-84654-9• SimonT.EnvironmentalRiskAssessment:AToxicologicalApproach.(2014)TextbookforGraduateRisk

AssessmentCourses,CRCPressISBN978-1466598294

PEER-REVIEWED JOURNAL ARTICLES • BellSM,ChangX,WambaughJF,AllenDG,BartelsM,BrouwerKLR,CaseyWM,ChoksiN,FergusonSS,

FraczkiewiczG,JarabekAM,KeA,LumenA,LynnSG,PainiA,PricePS,RingC,SimonTW,SipesNS,SprankleCS,StricklandJ,TroutmanJ,WetmoreBA,KleinstreuerNC.(2017)Invitrotoinvivoextrapolatinforhighthroughputprioritizationanddecisionmaking.ToxicolInVitro47:213-227.

• BeckerRA,DreierDA,ManibusanMK,CoxLA,SimonTW,BusJS.(2017)HowWellCanCarcinogenicityBePredictedByHighThroughput“CharacteristicsofCarcinogens”MechanisticData?RegulToxicolPharmacol80:185-196

TedSimon,Ph.D.,DABT Page2of19

January2018

• SimonTW,ZhuY,DoursonML,BeckN.(2016)BayesianMethodsforUncertaintyFactorApplicationforDerivationofReferenceValues.RegulToxicolPharmacol80:9-24.

• BeckNB,BeckerRA,ErraguntlaN,FarlandWH,GrantRL,GrayG,KirmanC,LakindJS,LewisRJ,NanceP,PottengerLH,SantosSL,ShirleyS,SimonT,DoursonML.(2016)Approachesfordescribingandcommunicatingoveralluncertaintyintoxicitycharacterizations:U.S.EnvironmentalProtectionAgency'sIntegratedRiskInformationSystem(IRIS)asacasestudy.EnvironInt89-90:110-128.

• BeckerRT,PatlewiczG,SimonTW,RowlandsJC,BudinskyRA(2015)Theadverseoutcomepathwayforrodentlivertumorpromotionbysustainedactivationofthearylhydrocarbonreceptor.RegulToxicolPharmacol73:172-90.

• SimonTW,BudinskyRA,RowlandsJC.(2015)AModelforArylHydrocarbonReceptor-ActivatedGeneExpressionShowsPotencyandEfficacyChangesandPredictsSquelchingduetoCompetitionforTranscriptionCo-activators.PLOSONE,10(6):e0127952

• BeckerRA,FriedmanKP,SimonTW,MartyMS,PatlewiczG,RowlandsJC.(2014)Anexposure:activityprofilingmethodforinterpretinghigh-throughputscreeningdataforestrogenicactivity-Proofofconcept.RegulToxicolPharmacol71:398-408.

• PatlewiczG,SimonTW,RowlandsJC,BudinskyRA,BeckerRA.(2015)Proposingascientificconfidenceframeworktohelpsupporttheapplicationofadverseoutcomepathwaysforregulatorypurposes.RegulToxicolPharmacol71:463-477.

• SimonTW,SimonsSSJr.,PrestonRJ,BoobisAR,CohenSM,DoerrerNG,Fenner-CrispPA,McMullinT,McQueenCA,RowlandsJC(2014)TheUseofModeofActionInformationinRiskAssessment:QuantitativeKeyEvents/Dose-ResponseFramework(Q-KEDRF)forModelingtheDose-ResponseforKeyEvents.CritRevToxicol44Suppl3:17-43.

• Budinsky,RA,SchrenkD,SimonT,VandenBergM,ReichardJF,SilkworthJB,AylwardLL,BrixA,KaminskiN,PerdewG,StarrTB,WalkerNJ,RowlandsJC(2014)Modeofactionanddose-responseframeworkanalysisforreceptor-mediatedtoxicity:thearylhydrocarbonreceptorasacasestudy.CritRevToxicol44(1):83-119

• PatlewiczG,SimonT,GoyakK,PhillipsRD,RowlandsJC,SeidelSD,BeckerRA.(2013)UseandValidationofHT/HCAssaystosupport21stcenturytoxicityevaluations.RegulToxicolPharmacol65(2):259-68.

• StephensML,AndersenM,BeckerRA,BettsK,BoekleheideK,CarneyE,ChapinR,DevlinD,FitzpatrickS,FowleJR,HarlowP,HartungT,HoffmannS,HolsappleM,JacobsA,JudsonR,NaidenkoO,PastoorT,PatlewiczG,RowanA,SchererR,ShakihR,SimonT,WolfD,ZurloJ.(2013)WorkshopReport:Evidence-basedToxicologyforthe21stCentury:OpportunitiesandChallenges.ALTEX30:74-103.

• PatlewiczG,SimonT,GoyakK,PhillipsRD,Rowlands,JCR,SeidelSandBeckerRA(2013)UseandValidationofHT/HCAssaystoSupport21stCenturyToxicityEvaluations.RegulToxicolPharmacol5:1-7.

• KirmanC,Budinsky,RA,YostL,BakerBF,ZabikJM,RowlandsJC,LongTF,SimonT(2011)DerivationofSoilClean-UpLevelsfor2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD)ToxicityEquivalence(TEQD/F)inSoilThroughDeterministicandProbabilisticRiskAssessmentofExposureandToxicity.HumanandEcologicalRiskAssessment17(1):125-158.

• BudinskyRA,LeClyuseEL,FergusonSS,RowlandsJC,SimonT(2010)HumanandRatPrimaryHepatocyteCYP1A1and1A2Inductionwith2,3,7,8-Tetrachlorodibenzo-p-dioxin(TCDD),2,3,7,8-Tetrachlorodibenzofuran(TCDF)and2,3,4,7,8-Pentachlorodibenzofuran(4-PeCDF).ToxicolSci118(1):224-235.

• SimonT(2010)JustWhoisatRisk?TheEthicsofEnvironmentalRegulation.HumExpToxicol30(8):795-819.• SimonT,Kirman,CR,AylwardLL,BudinskyRA,RowlandsJC(2009)EstimatesofCancerPotencyof2,3,7,8-

Tetrachlorodibenzo(p)dioxinusingLinearandNon-linearDose-ResponseModelingandToxicokinetics.ToxicolSci112(2):490-506.

• SimonT,Kirman,CR,AylwardLL,BudinskyRA,RowlandsJC,LongT(2008)EstimatesofCancerPotencyFor2,3,4,7,8-PentachlorodibenzofuranUsingBothNonlinearandLinearApproachs.ToxicolSci106(2):519-537.


January2018

• SimonT,BrittJK,JamesRC(2007)DevelopmentofaNeurotoxicEquivalenceSchemeofRelativePotencyforAssessingtheRiskofPCBMixtures.RegulToxicolPharmacol48:148-170.

• SimonTandManningR(2006)DevelopmentofaReferenceDoseforthePersistentCongenersofWeatheredToxaphenebasedoninvivoandinvitroeffectsRelatedtoTumorPromotion.RegulToxicolPharmacol44:268-281.

• SimonT(2000)InDefenseofRiskAssessment:aReplytotheEnvironmentalJusticeMovement’sCritique.HumanandEcologicalRiskAssessment6(4):556-560.

• EnglehardtJD,SimonT(1999)OrderAmidUncertainty.CivilEngineering,AmericanSocietyofCivilEngineers,69(6):8A-13A.

• SimonT(1999)Two-DimensionalMonteCarloSimulationandBeyond:AComparisonofSeveralProbabilisticRiskAssessmentMethodsappliedtoaSuperfundSite.HumanandEcologicalRiskAssessment5(4):823-843.

• SimonT(1997)CombiningPhysiologicallyBasedPharmacokineticModelingwithMonteCarloSimulationtoDeriveanAcuteInhalationGuidanceValueforTrichloroethylene.RegulToxicolPharmacol26:257-270.

• SimonT,BarnesK(1995)OlfactionandPreySearchinthecarnivorousleech,Haemopismarmorata.JExpBiol199:2041-2051.

• SimonT,DerbyCD(1995)MixtureSuppressionwithinhibitionforbinarymixturesfromwholecellpatchclampstudiesofinsituolfactoryreceptorneuronsofthespinylobster.BrainRes678(1-2):213-224.

• SimonT,Schmidt,J,CalabreseRL(1994)ModulationofHighThresholdTransmissionBetweenHeartInterneuronsoftheMedicinalLeechbyFMRF-NH2.JNeurophysiol71:454-466.

• SimonT,OpdykeCA,CalabreseRL(1992)ModulatoryeffectsofFMRF-NH2ontheoutwardcurrentsandoscillatoryactivityinheartinterneuronsofthemedicinalleech.JNeurosci12(2):525-537.

• SimonT,EdwardsDH(1990)Light-evokedwalkingincrayfish:Behavioralandneuronalresponsestriggeredbythecaudalphotoreceptor.JCompPhysiolA166:745-755

• HersheySJ,SimonT,BasteC(1975)Histochemicallocalizationofcytochromeoxidaseingastricmucosa.JHistochemCytochem4:271-282.

ABSTRACTS • SimonTW,ZhuY,DoursonML,BeckNB.(2016)BayesianMethodsApplication:ProofofConceptand

Pitfalls.SocietyofToxicologyAnnualMeeting,NewOrleans,LA• SimonTW,BeckNB(2015)BayesianMethodsforUncertaintyFactor(UF)Application:ProofofConcept.

SocietyofRiskAnalysisAnnualMeeting,T2-A.3,Arlington,VA• CanadyRA,SimonTW.(2015)DisruptiveArrivalofBigDatatoFoodIntakeAssessment.SocietyofRisk

AnalysisAnnualMeeting,M2-H.1,Arlington,VA• RuizP,SimonT,MumtazM(2014)InterpretingNHANESBiomonitoringData:Dioxins.Abstract96d,The

Toxicologist—AnofficialJournaloftheSocietyofToxicology,Volume138,Issue1,March• BeckerR,SimonT,Patlewicz,G,KennedyS,FarhatA,BudinskyR.(2014)ImprovingTheDevelopmentOf

AdverseOutcomePathways:LessonsLearnedFromTheAHRRodentLiverTumorandAHRAvianTeratogenicity/EmbryolethalityAOPs.Abstract2253TheToxicologist—AnofficialJournaloftheSocietyofToxicology,Volume138,Issue1,March

• SimonT.(2014)EvidentiaryStandardsforNeuroactiveandNeurotoxicDrugTesting(2014)Abstract723,TheToxicologist—AnofficialJournaloftheSocietyofToxicology,Volume138,Issue1,March

• BeckerR,PatlewiczG,SimonT,GoyakK,PhillipsR,RowlandsJC,SeidelS.(2013)ValidationofHigh-ThroughputandHigh-Content(HT/HC)AssaystoSupport21stCenturyToxicityEvaluations.Abstract2267.TheToxicologist—AnofficialJournaloftheSocietyofToxicology,Volume132,Issue1,March

• SimonT,StephensM,YangY,ManningR,RowlandsJC,BudinskyRA(2012)Applyingthe“ScienceandDecisions”ConceptualModels”toDioxin.Abstract133.TheToxicologistCD—AnofficialJournaloftheSocietyofToxicology,Volume126,Issue1,March


January2018

• Simon,T,RowlandsJC,BudinskyRA(2011)TheToxicEquivalenceFactorfor2,3,7,8-Tetrachlorodibenzofuran(TCDF):ToxicokineticandToxicodynamicConsiderations.OrganohalogenCompounds73:1003-1006.

• SimonT(2010)UsingHumanInVivoAHRActivationasaFunctionalDoseMetricforRiskAssessmentbasedonChloracne,EffectsinKeratinocytesandBackgroundCYPInduction.OrganohalogenCompounds62:582-585.

• SimonT,BudinskyRA,RowlandsJC,AbelTA(2010)Linearvs.NonlinearExtrapolationforDose-ResponseAssessmentofTCDD.OrganohalogenCompounds72:1418-1421.

• HawsL,TachovskyA,StaskalD,AylwardL,BurkhalterB,UrbanJ,SimonT,HarrisM(2010)AnEvaluationoftheInfluenceofDifferentSoilCleanupLevelsontheConcentrationofDioxin-LikeCompoundsinHumanSerum.OrganohalogenCompounds72:1448-1449.

• HarrisM,TachovskyA,StaskalD,AylwardL,BurkhalterB,SimonT(2010)SerumConcentrationsofDioxin-LikeCompoundsinaPopulationofMidlandMichigan:AnEvaluationoftheImpactofSoilExposures.OrganohalogenCompounds72:1442-1443.

• SimonT,GoodrumPE(2010)AComparisonofThreeDifferentMethodsofChildrens’SoilIngestion.TheToxicologist,#1916

• HawsL,TachovskyA,StaskalD,SimonT,BurkhalterK,HarrisMA(2010)EvaluationoftheImpactofSoilExposurestoDioxin-LikeCompoundsonBodyBurdeninaPopulationinMidland,Michigan.TheToxicologist,#1871

• HarrisMA,TachovskyA,StaskalD,SimonT,BurkhalterK,etal.(2010)AssessmentoftheImpactofVariousSoilCleanupLevelsonSerumConcentrationsofDioxin-LikeCompoundsinHumans.TheToxicologist,#1872

• SimonT(2009)CancerPotencyEstimatesfor2,3,7,8-TCDDdevelopedfromtheNationalToxicologyProgramBioassayResults,TheToxicologist,Program#EA1-2251

• SimonT(2009)WhyHumansareLessSensitivetoPCBsthanRhesusMonkeys,TheToxicologist#EA4-2254• KirmanC,BudinskyR,YostL,RowlandsC,LongT,SimonT(2008)DevelopmentofaDirectContact

Criterion(DCC)for2,3,7,8-TCDDinSoilUsingDeterministicandProbabilisticMethods.OrganohalogenCompounds70:1204-1207.

• KirmanC.,CrouchE,AylwardL,SimonT,BudinskyR,LandenbergerB,LongT(2007)CancerPotencyEstimateFor2,3,4,7,8-Pentachlorodiobenzo(P)Dioxin(4-PeCDF)TheToxicologist,Program#1561,p323.

BOOK CHAPTERS • VinasRandSimonTW(2017)RiskAssessmentinthe21stCentury:NewTechnologiesandTechniquesin

HistoryofRiskAssessmentinToxicology,1stEdition,SolBobst,Ed.,AcademicPress,ISBN:9780128095324• SimonT,EdwardsDH(1990)TheCaudalPhotoreceptor:AMultifunctionalSensoryNeuronmayselectits

OutputsbySpikeFrequency.InFrontiersinCrustaceanNeurobiology,WieseK,KrenzW-D,TautzJ,ReichertH,MulloneyB(eds.)Birkhauser-Verlag,Basel,Boston,Berlin ISBN:978-3-0348-5691-1

Grants,AwardsandHonors2012-15GrantfromtheDowChemicalCompany.Developmentofamodeloftheeffectsoftheavailabilityof

coregulatorproteinsongenetranscription.2009 HonorableMention,RiskAssessmentSpecialtySectionoftheSocietyofToxicology,bestpaperofthe

year:SimonT,Kirman,CR,AylwardLL,BudinskyRA,RowlandsJC(2009)EstimatesofCancerPotencyof2,3,7,8-Tetrachlorodibenzo(p)dioxinusingLinearandNon-linearDose-ResponseModelingandToxicokinetics.ToxicologicalSciences112(2),490-506.

2005 RecognitionfromtheSouthWireCompanyforinnovativeapproachestoEnvironmentalCleanup2005 EPABronzeMedalforTestimonyintheNormanMayescaseinKnoxville,TNthatledtoadditionalUST

regulationsbeingpassedbytheStateofTennessee


January2018

2005 EPABronzeMedalforDevelopingGuidanceonMonitoringLandUseControls2002 EPAScienceAchievementAwardforProbabilisticRiskAssessmentGuidance1995 EPABronzeMedalforCommendableService;Forleadershipinsettingtheexampleinself-directedwork

teammanagementandinsettingtheexamplein"fast-track"multimediaenvironmentalinvestigationandcleanup

1992 EnvironmentalEducationEnterprisesScholarshipinEnvironmentalScience,"PrinciplesofEnvironmentalDrillingandSampling,"AssociationofEngineeringGeologists,Atlanta,GA

1992 SpecialAwardfromtheVicePresidentforResearch,GeorgiaStateUniversity,"Evolutionofdifferentpreychoiceandfeedingstrategyintworelatedspecies,"$1000

1989 NationalResearchServiceAwardF32NS08394-01A1fromNIH-NINCDS"ModulationofIonicChannelsinanOscillatoryNetwork,EmoryUniversity,$41,000

1989 HonorableMention,DonaldB.LindsleyPrizeinBehavioralNeuroscienceforPh.D.Thesis,HonorableMentionforPh.D.thesis,"TheNeuralBasisofLightEvokedWalkinginCrayfish,"SocietyforNeuroscience

Education1989 Ph.D.Neurobiology&Behavior,GeorgiaStateUniversity,Atlanta,GA1971 B.A.Biology,MiddleburyCollege,Middlebury,VT

ProfessionalMemberships• 2006– RoundtableofToxicologyConsultants• 1995- SocietyofToxicology• 1997– SocietyforRiskAnalysis• 1984–1993 SocietyforNeuroscience• 2016- TheToxicologyForum

InvitedLectures2017 “ScientificIssueswiththe“New”TSCARiskAssessmentProcess,”ACIToxicTortandEnvironmental

LitigationConference,Chicago,IL2016 “BayesianMethodsforApplicationofUncertaintyFactors,”SocietyofToxicologyAnnualMeeting,New

Orleans,LA2016 “QuantitativePredictionofPhenotypicChangefromHighThroughputAssayResults,”EPAWorkshoponIn

VitrotoInVivoExtrapolation,February,ResearchTrianglePark,NC2015 “BayesianMethodsforApplicationofUncertaintyFactors,”SocietyforRiskAnalysisAnnualMeeting,

Arlington,VA2015 “ANewLookatToxicityFactorsforToxaphenerelatedtoFishConsumptionintheGreatLakes,”

PresentationtoTheGreatLakesConsortiumforFishAdvisories2014 “QuantitativeKeyEventRelationshipsintheAdverseOutcomePathway(AOP)forAHR-MediatedRodent

LiverTumorPromotionQuantitativeKeyEventRelationshipsintheAdverseOutcomePathway(AOP)forAHR-MediatedRodentLiverTumorPromotion,”InvitedSpeakeratameetingsponsoredbytheNationalInstituteofEnvironmentalHealthSciencesheldinBethesda,MD

2014 “EvidentiaryStandardsforNeuroactiveandNeurotoxicDrugTesting”InvitedSpeakerinaworkshopatthe2014meetingoftheSocietyofToxicology.

2013 “CurrentOutlookforImprovingUncertaintyandRiskCommunication.”InvitedSpeakeratUnderstandingandCommunicatingUncertaintyinHazardAssessment,aworkshopsponsoredbytheCenterforAdvancingRiskAssessmentScienceandPolicy(ARASP)oftheAmericanChemistryCouncil(ACC).

2013 FourLecturesinGraduateLevelEnvironmentalRiskAssessmentandRiskCommunication,UniversityofGeorgia,Athens,GA,Spring2013


January2018

2012 FourLecturesinGraduateLevelEnvironmentalRiskAssessmentandRiskCommunication,UniversityofGeorgia,Athens,GA,Spring2012

2011 “TheToxicEquivalenceFactorfor2,3,7,8-Tetrachlorodibenzofuran:Chemical-AdjustmentFactorsforAddressingTEFUncertainty.”Dioxin2011,Brussels,Belgium,August23,2011

2010 “Linearvs.NonlinearExtrapolationforDose-ResponseAssessmentofTCDD,”Dioxin2010,SanAntonio,TX,September15

2010 “UsingHumaninvivoAHRActivationasaFunctionalDoseMetricforRiskAssessmentBasedonChloracne,EffectsinKeratinocytesandBackgroundCYPInduction,”Dioxin2010,SanAntonio,TX,September13

2009 “DoseThresholdsinCancerRiskAssessment:Yes,theydoexist.”UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA,October26

2008 "Toxaphene–HowBadisthisPesticide?"UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA,October9

2008 "NaggingQuestionsaboutPCBs"UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA,October7

2008 "ToxicologyofPolychlorinatedBiphenyls(PCBs),"GeorgiaPowerToxicSubstancesControlActTraining,GeorgiaPowerHeadquarters,Atlanta,GA,July24.

2008 “NeurotoxicModesofActionofPolychlorinatedBiphenylsandBrominatedFlameRetardants:ImplicationsforEnvironmentalRegulation”,NationalInstituteofEnvironmentalHealthScience5thPCBWorkshop:NewKnowledgegainedfromoldpollutants,May16-22,IowaCity,IA,invitedbyDr.P.R.S.Kodavanti

2007 “NeurotoxicEquivalenceSchemeofRelativePotencyforAssessingtheRiskofPCBMixtures,”Dioxin2007,Tokyo,Japan,invitedbyDr.P.R.S.KodavantiofEPA,September.

2007 “ProbabilisticRiskAssessmentandExposure,”UniversityofGeorgia,DepartmentofEnvironmentalHealthScience,Athens,GA

2006 “Toxaphene–theWorld’sMostMisunderstoodPesticide,”UniversityofGeorgiaDepartmentofEnvironmentalHealthScienceSeminarSeries,Athens,GA

2005 "RegulatoryPerspectivesonProbabilisticRiskAssessment.”SocietyforRiskAnalysisandInterstateRegulatoryCouncilWorkshop.MichiganStateUniversity,EastLansing,Michigan

2004 “NewDirectionsinEnvironmentalIssues:anEPAPerspective.”PanelDiscussionattheGeorgiaEnvironmentalLawSeminar,SaintSimonsIsland,GA

2003 "ProbabilisticApproachestoDose-ResponseAssessment."LecturetoEPA'sRiskAssessmentForum,Washington,DC

2000 “ProbabilisticRiskAssessment:StepbyStep,”SponsoredbyNIEHS,EPAandtheUniversityofFlorida,SafetyHarbor,FL

1999 “EPA’sNewGuidanceonCitizenInvolvementinSuperfundRiskAssessment–WhatLawyersandRiskProfessionalsNeedtoKnow.”PanelDiscussionattheSocietyofRiskAnalysisAnnualMeeting,Atlanta,GA

1999 “CalculatingCleanupLevelswithMonteCarlo:RegulatoryConcernsandPerspective.”WithinasymposiumorganizedbyScottFerson,SocietyforRiskAnalysisAnnualMeeting,Atlanta,GA

1999 “PracticalIssuesintheUseofProbabilisticRiskAssessmentandItsApplicationtoHazardousWasteSites,”sponsoredbyNIEHS,EPAandtheUniversityofFlorida,Sarasota,FL

1996 "EvaluatingtheRiskofLiverCancerfromOccupationalExposuretoTrichloroethylenewithPBPKModelingandMonteCarloSimulation.”ChemicalIndustryInstituteofToxicology,ResearchTrianglePark,NC

KeyExperienceLITIGATION SUPPORT / WORK FOR LEGAL APPLICATION 2018 ExpertConsultationandDepositionaboutinterpretationofpostmortemdruglevelsinblood Providedverbalopinionstoattorneys;gavedepositiontestimonytoopposingcounsel.


January2018

2017 ExpertTestimonyonPhosphatidylethanol(PEth)inBlood Gavetestimony(examinationandcross-examination)inBartowCounty,GAfamilycourttoprovide

contexttoPEthbloodlevelsasamarkerofchronicalcoholconsumption2017 ExpertConsultationaboutalcoholasafactorinamotorvehicledeathinadramshopmatter Providedconsultationandwroteanexpertreportusingantemortemandpostmortemalcohol

estimationsandtheabilityofserverstorecognizeimpairment/intoxication.2017 ExpertTestimonyabouttheeffectsanddispositionofmarijuanainaWorkman’sCompcase Underwentexaminationandcross-examinationaboutthesignificanceofmeasurementsofTHCandits

metaboliteTHCCOOHasacausalfactorinatrafficaccident.2017 ExpertTestimonyinaDUIcase ProvidedtestimonyaboutthevalidityofareadingfromtheAlcometerV-XLandalcohol

pharmacokinetics.2017 ExpertLitigationSupport(ongoing)aboutoccupationalexposuretosolventsataCementPlant Developedmodelofexposuretosolventvaporsoccurringinatestinglaboratorywithmultiplefume

hoodstoassesstheeffectsofmixedsolventexposureoncognitivedeficitsinaworker.2017 ExpertOpiniononPhosphatidylethanol(PEth)inBlood Pethconcentrationsprovideameasureoftheamountofchronicalcoholconsumption;providedan

estimateofdailyalcoholusecorrespondingtospecificPethconcentrations.2017 ExpertOpiniononDrugUsebyaTruckDriver ConsidereddepositionandbloodtestresultstodetermineiftheuseofAdderallwasacontributingfactor

toanaccident.2017 ExpertOpiniononAlcoholBloodTesting Readmedicalrecordsandbloodtestforalcoholtodetermineifabloodtestabout15hoursafteran

injurywasusefulindeterminingimpairmentatthetimeoftheinjury.2017 ExpertReportonTHCTestResultsinBloodandUrineandCognitive/PsychomotorEffects Consideredmedicalrecordsanddrugtestresultsfromanemployeeinjuredatworktoconcludewhether

marijuanausemayhavecontributedtotheinjury.2016 ExpertConsultationonChemicalsfoundinFloorCoveringsandPossibleLinkstoMultipleChemical

Sensitivity Examinedmaterialsafetydatasheets,depositiontranscriptsandthescientificliteraturetodeterminethe

whetheramanufacturedfloorcoveringcouldaccountforeffectsinhumans.Testimonyexpectedinearly2017.

2016 ExpertConsultationontheEffectsofPrescribedAnti-Depressants,OpiatesandEpilepsyMedicationsduringPregnancy

Wroteanopinionabouttheeffectsofthesevariousdrugsduringpregnancy,includingpossibleeffectontheinfantafteritsbirth.

2016 ExpertConsultationonEffectsofAnti-DepressantandOpiateDrugsinHumans Providedawrittenopinionregardingthecombinedeffectsofaselectiveserotoninreuptakeinhibitor,a

benzodiazepineandanopiateonanindividual’smentalstate.Exposuretothesedrugslikelyoccurredfromapoisoningattempt.

2016 OpinionontheInterpretationofPositiveUrineTestsforMarijuanafollowingWeightLoss WroteanopinionregardingtheincreasesobservedinthelevelsofTHC-COOH(metaboliteofTHCfrom

marijuana)inurinethatareduetoreleaseofTHCfromfat.TheTHCwaslikelyusedseveralweeksormonthspriortotesting.

2016 ConsultationabouttheAssociationofDisinfectionByproductsinDrinkingWaterwithVariousHealthEffects

Conductedaninvestigatedofthescientificliteratureregardingaclaimthatchlorineandtrihalomethaneswereassociatedwitharangeofdiseases,includingkidneydiseaseandcancer.


January2018

2015-16 ExpertReportontheToxicityofDioxin-likeChemicals Providedareportanddepositionondifferencesintoxicityofthevariousdioxin-likechemicals.2015 ConsultationwithaWaterUtilityregardingtheHealthEffectsofRadiuminDrinkingWater Workedwithahealthphysicisttodevelopajointopinionaboutthehealtheffectsofradiumand

potentialtreatmenttechnologiestoenabletheutilityinanacquisition.2015 DepositiontoStateandFederalEnvironmentalRegulatorsandPrivateSectorAttorneysaboutthe

EffectsofSeleniumonHumanHealth ProvideddepositionregardingthetoxicityofseleniumdischargedintostreamsnearAppalachiancoal

mines.2015 ExpertReportontheLikelihoodofFungalEyeInfectionafterContactwithFertilizer Investigatedexposureofplaintifftoairbornefertilizerparticlesduringspreadingoperations.Thefertilizer

particlesenteredtheeyeandfungalinfectionofthecorneaensued.Wroteareportthatresultedinimmediatesettlementinfavoroftheplaintiff.

2015 ExpertOpinionontheToxicityandHealthEffectsofSyntheticCannabinoidsInJanuary,providedamemorandumtotheFairfaxCounty,VAPoliceDepartmentdetailingthehealtheffectsofsyntheticcannabinoidsusedintheillegaldrugsknownas“spice”or“K-2.”

2014-15DevelopmentofStatisticalBackgroundScreeningMethodsforUseataPotentialSuperfundSiteInDecember,providedacomparisontobackgroundforconcentrationsofarsenicandpolycyclicaromatichydrocarbonsatasitecurrentlygoingthroughtheHazardRankingSystem.

2008-14ExpertConsultationandDepositiononRegulatoryDecisionsataSuperfundSiteProvidedanexpertreporttoattorneysabouthowthepresenceofdioxin-likechemicalsandPCBsaffectedtheregulatoryactivities/decisionsataSuperfundsiteinNewEngland.In2014,providedadepositioninWash.,DC.

2014 ReportonTSCAComplianceStatusofRecentDataandPublicationsontheHealthEffectsofChromiumPreparedareportonthedeterminationsofwhetherthesedataandpublicationscouldbeconsidered“new”information.Thepurposewastoprovideattorneyswithriskinformationasindicatedinthe1978TSCASection8(e)PolicyStatementonSubstantialRiskNotificationstoEPA.

2010 RebuttalReportonHexavalentChromium Preparedareportrebuttingareportsubmittedbytheexpertworkingforopposingcounselregardingthe

healthandenvironmentaleffectsofhexavalentchromium.2008-10ExpertTestimonyregardingtheEffectsofInorganicMercury

Providedanexpertreporttoattorneysinachildcustodymatterregardingthelongtermneurologicalandpsychologicaleffectsofinorganicmercury.ProvidedexperttestimonyonthismatterinfamilycourtinFultonCounty,GAregardingthetoxicityofinorganicmercury.

2009 ConsultationandStatisticalModelingregardingtheDose-ResponseofPerfluoroctanoicAcid(PFOA)inHumans

PFOAisusedintheproductionofTeflon.Providedconsultationaboutdose-responsemodelingasasub-contractortoaconsultingfirminTallahassee,FLtobeusedinlitigationsupport.

2009 ExpertConsultationregardingUSEPA'snewArsenicToxicityCriterionProvidedamemorandumtoattorneysandpersonnelfromelectriccompaniesontheramificationsofEPA'sproposedchangeintheoralcancerslopefactorforArsenic.

2008 RiskCommunicationandExpertConsultationregardingAerosolEmissionsRetainedasanexpertintoxicologybyattorneysforGeorgiaPowertoprovidescientificconsultationandriskcommunicationregardingemissionsofseveralinorganicchemicalsfrompowerplants.

2007 ProBonoEvaluationofExposuretopara-dichlorobenzene(PDB)ProvidedanexpertreportonexposureandpotentialliverdamageinanindividualworkinginabotanylaboratoryinwhichPDBwasusedasaninsectfumigantforplantspecimens.


January2018

2006 AssessmentofPossibleDrug/AlcoholImpairmentinforWorkman’sCompensationExaminedquickurinedrugscreenresultsshowingalcoholandmarijuanauseanddevelopedanassessmentofpossibleimpairment.

2006 ExpertConsultationontheRecentHistoryofArsenicRegulationbyEPAProvidedamemorandumdetailingthehistoryofarsenicregulationasasoilcontaminantbyEPAheadquartersandbyRegion4EPA(Southeast)since1988tosupporttheeffortsofattorneysregardingaSuperfundsite.

2006 ConsultingExpertregardingIndoorDampnessandMoldServedasaconsultingexpertregardingadverseeffectsofexposuretoindoordampness,associatedmoldandbacteriaandthedisinfectantchemicalsusedinthecleanup.

2003-4 ModelofChemicalReleasefromaRailroadTankCarDevelopedamathematicalmodelforthereleaseanddispersionofadensegas,ethylacrylate,fromarailroadtankcar.Thegasproducedorganolepticeffects,andathigherexposure,toxiceffects.Sourcecharacteristicswereobtainedusingbasicphysicalchemicalprinciples.Dispersionmodelingwasperformedfordensegasdispersionincomplexterrain.

2003 ExpertTestimonyinEPAvs.NormanC.MayesAsanEPAtoxicologist,providedtestimonytoAdministrativeLawJudgeBarbaraGunningregardingthehealtheffectsofbenzeneandotherfuelcomponentsandenvironmentalsamplingaroundundergroundstoragetanks.

2002-4 AirandExposureModelingandPBPKModelDevelopmentofCreosoteExposureataWoodTreatmentFacilityDevelopedacomprehensivedatabaseofchemicalsinwoodpreservativemadewithcoaltarcreosote,amathematicalmodeloftheairconcentrationsofthesechemicalsatawoodtreatmentfacility,andasecondmodelforhumaninternalexposuretothesechemicalsthatincludedingestion,inhalationanddermalroutes.

2001-2 ExpertTestimonyregardingCalibrationoftheIntoxilyzer5000DevelopedtestimonyregardingthecalibrationproceduresoftheIntoxilyzer5000,the"breathalyzer"usedinGeorgiaforDUItesting.ChargesinDUIcasesweredroppedpriortohistestimonyinthethreecasesinwhichDr.Simonwasinvolved.

2000 ChemicalReleasefromaRailroadTankCarDevelopedamodelofreleaseandtransportofacrylamidefromarailroadtankcarforuseinlitigation.

TEACHING 2014 Instructor,EnvironmentalRiskAssessmentandCommunication,EHSC8110,UniversityofGeorgia

TaughtagraduatelevelcourseIntheSchoolofPublicHealthusinghistextbook,“EnvironmentalRiskAssessment:AToxicologicalApproach.”

2008 LectureontheToxicologyofPCBsDevelopedandpresentedatrainingsegmentaspartoftheToxicSubstanceControlAct(TSCA)trainingforelectricpowercompanypersonnelattheGeorgiaPowerCompany.

2008 IntroductiontoRiskAssessment,atwo-dayclassfortheOntarioMinistryofEnvironmentWithanotherscientist,developedandtaughtaclassonriskassessmentfornewlyhiredMinistrypersonnel.

2005 ProbabilisticRiskAssessmentandStatistics,ashortcoursetoMichiganDepartmentofEnvironmentalQualityWithanotherscientist,presenteda1½dayclassonprobabilisticriskassessmentandstatisticsaspartofaworkshopsponsoredbytheSocietyforRiskAnalysisandInterstateTechnologyRegulatoryCouncil.


January2018

2003 GraduateCourseinSimulationModeling,GeorgiaStateUniversityTaughtagraduatelevelcourseinSimulationModelingincludingstatistics,probabilisticmethodsandtime-dynamicdifferentialequationmodels.

2003 ShortCoursetoOntarioMinistryofEnvironmentonProbabilisticRiskAssessmentWithanotherscientist,developedandtaughtaclassonprobabilisticriskassessment,includingprobabilisticapproachestodose-responsetopersonnelattheOntarioMinistryofEnvironmentinToronto,Canada

2001-06UniversityofGeorgiaGraduateCourseinEnvironmentalRiskAssessmentOnthreeseparateoccasions,taughtagraduate-levelclassonEnvironmentalRiskAssessmentlasting15weeks,3hoursperweek.

2001 ShortCoursetoTexasNaturalResourcesConservationCommissiononProbabilityDistributionsWithanotherscientist,developedandtaughtaclassonstatisticsandprobabilitydistributionstodatatoTNRCCpersonnel.

2000 WorkshopsonProbabilisticRiskAssessmentPerformedasanEPAtoxicologist.In1999and2000,workedwithDr.SteveRobertsoftheUniversityofFloridatoorganizetwoworkshopsonPRAsponsoredbyEPA,NIEHSandtheUniversityofFlorida.

1999 ShortCoursetoTexasNaturalResourcesConservationCommissiononProbabilisticRiskAssessment Withanotherscientist,developedandtaughtaclassonprobabilisticriskassessmenttoTNRCCpersonnel.1997 ShortCoursetoNavyEnvironmentalHealthCenterpersonnelonProbabilisticRiskAssessment

Withanotherscientist,developedandtaughtaclassinprobabilisticriskassessmentNavypersonnelinNorfolk,VA.

PRODUCT LIABILITY AND SAFETY EVALUATIONS 2013 PresentationtoaFrenchGovernmentAgencyonProductSafety

ProvidedareportwithestimatesofbothtoxicityandexposuretorailworkersontheuseofasyntheticdielectriccompoundmanufacturedbyacompanyintheUK.MetwithFrenchgovernmentpersonneltodiscussthereport.

2012 AssessmentofRiskfromMetalPlatingFlakingfromanAuxiliaryFaucetusedwithaWaterFilter Developedriskestimatesforwaterconsumersfromdissolvedmetalsandmetalflakesfromthefaucet.This

assessmentwasusedinternationallyandthereforeincorporatedWorldHealthOrganizationmethodology.

REGULATORY TOXICOLOGY 2018 LeadAuthorofaDocumentDevelopingToxicityReferenceValuesforInorganicArsenic ThereportwasdevelopedforHealthCanada,theCanadianequivalentoftheUSEPA.Datafrommany

largeepidemiologicstudieswereusedforexposure-responsemodelinganddevelopmentofTRVssuchasreferencedosesandcancerslopefactor.CustomsoftwaretoperformthemodelingwasdevelopedintheRsoftwarelanguage.

2017 ReporttoChemicalIndustryTradeGrouponPerfluorinatedCompounds Thesecompoundshavebeenusedforstainresistanceandwaterproofingformanyyears.Theyare

ubiquitousintheenvironmentandhumanbodyburden.Thereportprovidesadviceaboutwhichcompoundsbeartheleastrisktohumanhealth.

2016-17LeadAuthorofaToxicologicalReviewofInorganicArsenicandOrganicArsenicals ThereviewwasdevelopedforHealthCanada,theCanadianequivalentoftheUSEPAandthepurposewas

toexaminethefeasibiityoftheintegratinghuman,animalandinvitrolaboratorydatatoprovideanupdatedtoxicityevaluationofarsenic.

2016 Publicationtitled“HowWellDoHTSCarcinogenCharacteristicsPredictCarcinogenicity?” Providedstatisticalanalysis,graphicsandnarrativedevelopmentforthispaperincollaborationwith

scientistsfromuniversitiesandindustrytradegroups.


January2018

2016 AnalysisofChemicalSimilarityforAbuseLiabilityofCandidateDrugMolecules Conductedastatisticalanalysisofchemicalsimilaritybetweentwocandidatedrugsandsubstancesonthe

DEAControlledSubstanceListtoaddresstheissueofpotentialabuseliability.2015-16WhitepaperonCausalAssociationsbetweenFlameRetardantExposureandFirefighters’Diseases

DevelopedfortheFlameRetardantsAlliance.2015 AdverseOutcomeSummaryPathwaysforChemicalswithUncertaintyabouttheModeofAction Adverseoutcomepathways(AOPs)arebeingusedbyEPAandOECDtoformadatawikiforeventual

interpretationofhigh-throughputinvitrodata.DevelopedseparatesummariesofAOPsforfourchemicalscarcinogenicinanimalsusingtheassumptionofmutagenicityasmodeofactionandhyperplasia/cellproliferationasthemodeofaction.

2015 RevisionoftheToxicityFactorforthePesticideToxapheneforuseattheHerculessiteinBrunswick,GA Developedarevisedestimateofthetoxicitycriterion(ReferenceDose)forthepesticidetoxapheneforuse

inanewriskassessmentfortheHerculessiteinBrunswick,Georgia.2014-15ReportonBayesianStatisticalMethodsusedintheNRC(2014)ReviewofIRIS Developedareportexamining24toxicityfactorsfromEPA’sIntegratedRiskInformationSystemdatabase,

thesubjectofarecentreviewbytheNationalResearchCouncil.ThereportcomparedEPA’smethodswiththoserecommendedintheNRCreport.

2014 PresentationonarsenicandchromiumatEPA’sIntegratedRiskInformationSystem(IRIS)BimonthlyMeeting

InJune,presentedmodeofactioninformationforarsenicandhexavalentchromiumatEPA’sIRISmeeting.ThepurposeofthesemeetingsistoseekinputfromstakeholdersfordevelopmentofIRISriskassessments.

2013 PresentationonQuantitativeMethodsforModeofActionAnalysistoEPA’sBimonthlyIRISMeeting InDecember,presentedslidesanddiscussiontoEPAandotherstakeholdersbasedonthepaperwritten

withILSI/HESItitled“TheUseofModeofActionInformationinRiskAssessment:QuantitativeKeyEvents/Dose-ResponseFramework(Q-KEDRF)forModelingtheDose-ResponseforKeyEvents.”

2013-16DevelopmentofWikifilesontheAdverseOutcomePathwayfortheOrganisationforEconomicCooperationandDevelopment(OECD)

WroteandeditedwebpagesforuseinthenewAOPWikisponsoredbyOECD,EPAandothers.ThepurposeofthecollectionofAOPsandtheWikiistocontextualizeinvitrodataforuseinriskassessment.

2013 PreparationofaReportProvidingDerivedLD50ValuesforMetalsinFlyAsh DosesofflyashrepresentingtheLD50formetalsweredevelopedforflyashproducedbyanincinerator

operatedbyalargecountygovernmentinsouthernCalifornia.2013 DevelopmentofEvidenceTablesforEPA’sIntegratedRiskInformationSystem(IRIS)Assessments Developedtabularformatforpresentingmodeofactionandtoxicityinformationconsistentwiththe

NationalAcademyofSciences’ReviewoftheEnvironmentalProtectionAgency'sDraftIRISAssessmentofFormaldehyde.PresentedthetablesandaccompanyingrationaletoEPAIRISstaffusinghexavalentchromiumasanexample.

2013 DevelopmentandPresentationofResponsestoChargeQuestionsforEPA’sFederalInsecticide,Fungicide,andRodenticideAct(FIFRA)ScientificAdvisoryPanel

Wroteresponsesonphysico-chemicalscreeningandtherainbowtroutExpertSystemforestrogeniceffects;presentedtheresponsesattheFIFRA/SAPmeetingatEPAHeadquarters.

2012 ReviewofEPA’sToxicologicalReviewofAmmonia ReviewedtheEPAdraftdocumentforammoniatodetermineconsistencywithrecommendationsfrom

theNationalAcademyofSciences.PresentedresultsatEPA’sIRISlisteningsessiononAmmonia.


January2018

2012 Reviewof2012TexasCommissiononEnvironmentalQuality(TCEQ)“GuidelinestoDevelopToxicityFactors”

TCEQdevelopsitsowntoxicitycriteriaanddoesnotdependonEPA’sIRISdatabase.PreparedcommentsontheguidanceforsubmissiontoTCEQ.

2012 PreparationofaWhitePaperandmanuscriptforpublicationonValidationofEPA’sToxCast™SuiteofHighThroughputInVitroAssays

Wrotenarrativepaperandmanuscriptforachemicalindustrytradegrouponissueswithvalidationoftheseassaysforchemicalscreeningandprioritization.

2011 DevelopmentofPhysiologically-basedPharmacokineticModelsforDioxin,PCBs,DDT,HexachlorobenzeneandOrganophosphatePesticidesforuseasteachingtoolsattheAgencyforToxicSubstancesandDiseaseRegistry(ATSDR)

DevelopedPBPKmodelsinBerkeleyMadonnasoftwareforuseasteachingaidsforpersonnelatATSDR.2011 ReviewofEPA’sPhysiologicallyBasedPharmacokineticModelforAcrylonitrileUsedintheIRISRisk

Assessment ReviewedtheMATLABcomputercodeandoutputforoptimizationofparametersusedinthismodel.

TOXICOLOGYANDREGULATORYANALYSISOFDIOXIN-LIKECHEMICALSINCLUDINGPOLYCHLORINATEDBIPHENYLS2012-15ModelingofDioxin-inducedGeneExpressioninBreastCancerCells

Developedamodelofgeneexpressionusingstochasticsimulationmethodsthatreproducedseveralphenomenasuchasnon-monotonicdoseresponsecurves.

2012 DevelopmentofaMarginofExposureforEnzymeInductionfromDioxinExposureforComparisonwithRecentEPAToxicityFactorsforaWeight-of-Analysis

Usingdatafrombothhumansandlaboratorytestspecies,determinedthedoseatwhichanincreaseinthyroidhormonemetabolismcouldbeexpectedandcomparedthisdosewiththecurrentEPAreferencedosebasedonthyroideffectsinnewborns.

2011 Inclusionof2009ReferenceDosefor2,3,7,8-Tetrachlorodibenzodioxin(TCDD)intheITERandTOXNETdatabases

Presentedconclusionsfroma2009publicationtoapeerreviewpanelconvenedbyToxicologyExcellenceinRiskAssessment(TERA)forplacementintheInternationalToxicityEstimatesforRiskAssessment(ITER)databaseandlinkedtotheTOXNETdatabaseattheNationalLibraryofMedicine.

2011 DevelopedaRevisedToxicEquivalenceFactor(TEF)for2,3,7,8-Tetrachlorodibenzofuran(TCDF) TCDFisadioxin-likechemicalthatismetabolizedandeliminatedwithinhoursincontrasttootherdioxin-

likechemicalsthatpersistinthebodyformanyyears;developedanestimateoftheTCDFTEFthatincorporatesthisrapidmetabolismforpresentationataninternationalconferenceinBrussels,Belgium.

2011 AllianceforRiskAssessmentPresentationonDioxinusingScienceandDecisionsConceptualModels PresentedresultsfromtheapplicationofdoseresponsemethodsdescribedNationalResearchCouncil's2009

Report"ScienceandDecisions:AdvancingRiskAssessment"todioxin.TheaudiencewasanexpertpanelthatincludedseveraloftheauthorsoftheNRCreport.

2010 ReportonBiota-SedimentAccumulationFactor(BSAF)forAroclor1260,aCommercialPCBMixture ProvidedareviewandcommentaryonthedevelopmentofaBSAFforAroclor1260(PCBmixture)andits

generalapplicabilitytoPCBcontaminatedsites.2010 RapporteurataWorkshoponDose-ResponseApproachesforNuclearReceptor-MediatedModesof

Action Ledpaneldiscussionandprovidedthepresentationofthereportforthepanelexaminingthemodeof

actionofthearylhydrocarbonreceptorthatmediatesgeneexpressionfromdioxin-likechemicals.2010 RiskAssessmentforDioxinbasedontheOccurrenceofChloracneinHumans Developedariskassessmentfor2,3,7,8-tetrachlorodibenzo-p-dioxinbasedsolelyondatafromhumans

andpresentedtheworkattheDioxin2010meetinginSanAntonio,TX.


January2018

2010 AnalysisofResponsesofHumanandRodentLiverCellstoDioxin-LikeChemicals Conductedstatisticalanalysisofgenomicandproteomicdatainresponsetothreedioxin-likechemicals

fromhumanandrodenttissuesinvitro.2010 CancerSlopeFactorsandToxicityEquivalenceFactorsforDioxin-LikeChemicalsbasedonInternalDoses Developedacomparisonofthetoxicityoffourdioxin-likechemicalsbasedontissueconcentrationsfrom

NationalToxicologyProgrambioassaysusingphysiologically-basedpharmacokineticmodelinganddoseresponsemodels.

2009 EvaluationofToxicityEquivalenceFactorsforDioxin-likeChemicalsbasedonexternaldoses DevelopedacomparisonofmethodsusedtodevelopvaluesforTEFsusedinriskassessmentsofdioxin-

likechemicals.2009 EPAFederalAdvisoryCommitteeAct(FACA)WorkshoponDIoxin Attendedworkshopontheriskassessmentof2,3,7,8-tetrachlorodibenzodioxin(TCDD);providedpublic

commentaryonEPA'sproposedmethodsforrevisingthe2003dioxinreassessment.2008 ReviewofPCBEcotoxicologyInformationintheBaselineEcologicalRiskAssessmentfortheLCP

ChemicalSuperfundSite,Brunswick,GA ReviewedthetoxicityassessmentforPCBsfortheecologicalriskassessmentforthissitetoensure

consistencywiththevaluesandapproachusedinthehumanhealthriskassessment.2007 ComparisonbetweenBloodLevelsofDioxininresidentsofMidland,MIandthoseinratsassociated

withAdverseEffects Conductedacomparisonbetweenhumanbloodlevelsof2,3,7,8-TCDDand2,3,4,7,8-PeCDFmeasuredin

humansintheUniversityofMichiganDioxinExposureStudyandestimatedbloodlevelsinratsfrombioassayspublishedbytheNationalToxicologyProgramin2006.

2007 DevelopmentofaRiskAssessmentMethodologyBasedonChangesinGeneExpression Withveryrecentinformationondioxin-relatedgeneexpressionchangesintheliver,developedamethod

forusingthesechangesasabiomarkerfortheprogressiontotype2diabetes.2007 WhitepaperontheNon-cancereffectsonhumansofDioxin-likeChemicals Collectedscientificinformationrelatedtopotentialandactualhumanhealtheffectsfrompublished

studiesoftheYu-Cheng/Yushopoisoning,theSevesoexposure,theBASFplantexposureandtheVietNamRanchhands(AgentOrangehandlers)andotherstoassessthelikelihoodofvarioushealthoutcomesfromdioxinexposure.

2007 SoilCleanupStandardsforDioxinrelatedtotheGeorgiaHazardousSubstancesResponseActforasecondarycoppersmelter

DevelopadioxincleanuplevelinsoilforconsiderationbytheGeorgiaEPDthatincludedanepidemiologicalstudyofdioxininthebloodofworkersatthesmelter.

2005 DevelopmentofSurrogateValuesforReportedDioxinConcentrationsBelowtheAnalyticalDetectionLimit

PerformedasanEPAtoxicologist;theuseofcontract-specifiedreportinglimitsasnondetectsurrogatesfordioxinanalysisleadstolargeoverestimatesofsoilconcentrations;identifiedamoreaccuratenondetectsurrogatevaluebasedontheactualchemicalanalysis.

2005 ReassessmentfortheNeedforPCBCongenerAnalysisattheAnniston/SolutiaPCBSite PerformedasanEPAtoxicologist;comparedresultsfromPCBcancerbioassaysofthecancerpotencyof

dioxin-likePCBs.2004-5 GeostatisticalmodelingofdioxinconcentrationsinsoilatSuperfundSitesinFlorida PerformedasanEPAtoxicologist;theseanalysesdemonstratedthatcleanupatthesesiteshadbeen

successfulandappropriateforthepredictedlanduse;theanalysesalsoshowedthatdioxinoccurringoff-sitewasunrelatedtoon-sitecontamination.


January2018

HUMAN HEALTH AND ECOLOGICAL RISK ASSESSMENT AND RISK COMMUNICATION 2014 DevelopmentofaProbabilisticRiskAssessmentforNellisDunesRecreationArea,Nevada WorkedinconjunctionwithacademicscientistsattheUniversityofNevada,MontanaStateUniversityand

theUniversityofSouthCarolinatousenewlydevelopedinformationofthegeologyofNellisDunesandsite-specifictoxicitybioassaysofdusttocompleteariskassessmentforexposuretodustatthisrecreationarea.

2012 ParticipationonaRiskAssessmentTeamdevelopingmethodologytoassessaSuperfundsiteconsistingofalargeareafloodplain

Evaluatedriskassessmentoptionsandlandusetosupportcleanupdecisionsatanimpactedareacomprisingseveralsquaremilesandmanyrivermiles.

2010 ScreeningLevelEcologicalRiskAssessment(SLERA)forasiteinFloweryBranchinHallCounty,Georgia Atanindustrialparknearaninterstatehighway,theareaofpotentialecologicalconcernconsistedofa

storm-waterretentionpondandastream.InvestigatedthesiteanddevelopedtheSLERAdocumentforsubmissiontotheGeorgiaEnvironmentalProtectionDivision.

2009 StreamlinedHumanHealthandEcologicalRiskAssessmentstosupportRemovalActionattheNabesnaMineSiteinNabesna,Alaska

ThissiteislocatedintheWrangell-St.EliasNationalParkandwasafunctioninggoldmineintheearly20thcenturywithhighconcentrationsofmetalsassociatedwithminetailingsandacidminedrainage;developedbothriskassessmentstosupportanon-time-criticalactionatthesite.

2009 DevelopmentofGeorgiaRiskReductionStandards(RRS)forDrexelChemicalCompanyinCordele,GAandanothersiteinNorthGeorgia

CalculatedGeorgiaRRSvaluesforthissite;negotiatedinpersonandbyteleconferencewithGeorgiaEnvironmentalProtectionDivisionpersonnelregardingtheappropriateuseoftoxicitycriteria.

2009 RiskCommunicationandRegulatoryReviewrelatedtotheTVACoalAshSpillinKingston,TN ProvidedriskcommunicationatpublicavailabilitysessionforboththeAmericanCoalAshAssociationand

TVA;reviewedsubmissionstoEPAdevelopedbyTVA.2008 QualityAssuranceforFishConsumptionRiskAssessmentonthePassaicRiver Reviewedandprovidedcommentsonboththeaccuracyandconceptualizationoftheriskassessment.2008 DevelopmentofGeorgiaRiskReductionStandardsforTrivalentandHexavalentChromiumandseveral

VolatileOrganicChemicals CalculatednumericalstandardsunderGeorgia'sHazardousSiteResponseRule391-3-19asa

subcontractorinsupportofapropertysaleandtransfer2008 EvaluationofSoilConcentrationsofArsenicwithanEmphasisonLocalBackgroundataPowerPlant DevelopedareportforsubmissiontotheGeorgiaEnvironmentalProtectionDivisionregardingareleaseof

wastematerialcontainingarsenicthatoccurredbystormwaterrunoff;thereportconsideredthegeologyandlocalbackgroundconcentrationandincludedastatisticalanalysis.

2008 StatisticalEvaluationofSolventDatainGroundwaterandCritiqueofATSDRHealthAssessmentofaSuperfundSite

ProvidedareportthatincludedsuggestionsandcommentsontheATSDRReport.PerformedastatisticalanalysistorefinetheconclusionsreachedandcritiquedthemethodologyfortheHealthAssessment.

2008 InvestigationintotheScientificBasisofLandDisposalLimitof50partspermillionforPCBs Underthe1979ToxicSubstancesandControlAct(TSCA),EPAhasplacedanupperlimitof50ppmforland

disposalofPCBs.Investigatedthescientificbasisofthisvalueforapplicationataformerchlor-alkaliplantsiteinNorthCarolina.

2008 ReviewofCleanupTargetLevelsofFloridaDepartmentofEnvironmentalProtection ProvidedareviewoftheCleanupTargetLevelsusedforregulationbyFloridaDepartmentof

EnvironmentalProtection.


January2018

2007 EvaluationofCalculationMethodsfortheGeorgiaRiskReductionStandardsoftheGeorgiaHSRAProgram

ExaminedRRSvaluesforsoilandgroundwaterdevelopedforasiteinnorthGeorgiaandprovidedanexplanationoftherationaleunderlyingdiscrepanciesinthecalculatedvalues.

2007-9 RiskAssessmentfortheExposuretoMercuryandPCBsfromcontactwithMarshSedimentandConsumptionofFishandGameBirdsattheLCPChemicalSuperfundSite,Brunswick,GA.

Conductedariskevaluationforsedimentexposureand,fishconsumptionwithdevelopmentofsite-specificfishconsumptionestimatesandasite-specificsedimentexposureestimateforanupdatedRemedialInvestigationReportforsubmissiontotheUSEnvironmentalProtectionAgency.

2007 ProBonoEvaluationofGeorgiaDNRFishAdvisoriesforPCBsandMercury EvaluatedcurrentfishadvisoriesnearBrunswick,GAforDr.RandyManning,theGeorgiastate

toxicologist.2007 GeorgiaRiskReductionStandardsforPCBs,mercuryandotherchemicalsinSoilandGroundwateratthe

LCPChemicalSuperfundSite Prepareddetailedcalculationsofsoilandgroundwaterscreeningvaluesbasedbothondirectexposure

andtransferofchemicalsfromsoiltogroundwater.2006-10RiskAssessmentfortheResidentialExposureScenarioforPCBsandmercuryinUplandSoilsattheLCP

ChemicalSuperfundSite,Brunswick,GA. Conductedariskevaluationforresidentialexposure.TheoriginalriskassessmentfortheLCPsitedidnot

includeanestimateofrisktoon-siteresidentsorotherhumanreceptorswithasmallexposureunit(ca.0.5acres).ThisriskevaluationwillbepartofanupdatedremedialinvestigationtosubmittoUSEPA.

2006-7 RiskAssessmentforConsumptionofEstuarineFishcontainingToxapheneResiduesbyCoastalGeorgiaResidentsrelatedtheHerculesChemicalSuperfundSiteinBrunswick,GA

DevelopedfishconsumptionestimatesforcoastalGeorgiaresidentsbasedontheprevioussurveysintheBrunswickareausedalongwithpublishedworkonthetoxicityoftoxaphenetosupportaprobabilisticriskassessmentforfishconsumptionpreparedforUSEPA.

2006 DevelopmentofaPhysiologically-basedPharmacokineticModelforCopperinMigratoryBirdsforEcologicalRiskAssessmentofMine-AssociatedTailingsPonds

Highcopperconcentrationsinwaterassociatedwithacidminedrainagemaybetoxictobirds;developedofaPBPKmodelofcopperabsorption,distribution,metabolismandexcretion(ADME)injuvenileducksandadultgeese;conductedafeasibilitystudyofincorporatingthephysiologicalchangesassociatedwithmigrationintothemodel.

2006 DevelopmentofaPreliminaryRiskAssessmentforSeleniumaspartofaProposaltoAddressOverallEffectsofSeleniuminaRiverSystem

Developedhumanhealthandecologicalriskestimatesforseleniummigratingfromcoalpilesintoariver.Theseestimatesincludedconsumptionoffishandwaterbyhumans.

2006 EvaluationofGeorgiaDNRFishAdvisoriesnearBrunswick,GA ConductedanevaluationoffishadvisoriesforToxapheneandPCBspublishedbytheGeorgiaDepartment

ofNaturalResources.2006 DevelopmentofawhitepaperpresentingthehistoryofProbabilisticRiskAssessment(PRA)atEPA ReviewedEPAguidancedocumentsandscientificliteratureandproducedadocumentthatdetailedthis

completehistoryofPRAatEPAandsuggestedlikelyusesofPRAinthefuture.2005 RiskCommunicationregardingsolventsingroundwateratAugusta,Georgia AsanEPAtoxicologist,providedinformationtocitizensatapublicmeetingregardingthepossiblehealth

effectsoftetrachloroethyleneandtrichloroethyleneingroundwaterrelatingtoaRCRAsite.2005 ReviewofProposedArsenicToxicityAssessmenttobeplacedonEPA’sIRISDatabase AsanEPAtoxicologistandconsensusreviewerforEPA’sIRISdatabase,reviewedandprovidedcomment

onproposedchangestothearsenictoxicityassessment.


January2018

2004-5 RiskCommunicationtoCommunityAgainstPollution(CAP),acitizensgroupinAnniston,AL AsanEPAtoxicologist,developedarelationshipwithCAPandpresentedinformationonthehealtheffects

ofPCBsatseveralpublicandcommunitymeetings.2004 ProvidenceParkEcologicalRiskAssessment Conductedascreeningecologicalriskassessment(SLERA)forasiteinFultonCounty,GA2004 RiskCommunicationregardingTrichloroethylene AsanEPAtoxicologist,providedinformationtotheCitizen'sAdvisoryGroup(CAG)atAnnistonArmy

Depotandagroupofconcernedcitizensaboutthehealtheffectsoftrichloroethylene.2003-5 DevelopmentofEPA'sGuidanceonSurfaceSoilCleanupatHazardousWasteSites:Implementing

CleanupLevels AsanEPAtoxicologist,developedaguidancedocumentthatpresentedmethodsforapplyingrisk-based

cleanuplevelsasareaaveragesratherthannot-to-exceedlevels.2003 SoilCleanupStrategyforaSkeetRangeatNavalAirStationCecilFieldinJacksonville,FL. AsanEPAtoxicologist,usedbothgeostatisticsandexposureassessmenttorefinethesizeofthearea

needingremediation.2000 DiscussionofFlorida’sSecondaryDrinkingWaterStandardsbasedonOrganolepticEffects AsanEPAtoxicologist,investigatedthebiologicalbasisofFlorida’ssecondarydrinkingwatercriteriafor

aluminum,iron,manganeseandsilverforwhichsecondarystandardsbasedonesthetics(smellandtaste)werebelowhealth-basedcriteria.

2000 MemorandumpresentingAmendedGuidanceonEcologicalRiskAssessmentatMilitaryBases:ProcessConsiderations,TimingofActivities,andInclusionofStakeholders

AsanEPAtoxicologist,authoredamemothatenabledecologicalriskassessmentsatDODfacilitiestobecompletedinatimelymannerandensuresthatriskassessmentactivitiesoccurattimesconsistentwithDODfundingschedules.

1996-9 DevelopmentofRiskAssessmentGuidanceforSuperfund,Part3.ProcessforConductingProbabilisticRiskAssessment

AsanEPAtoxicologist,madesignificantcontributionstothisguidance,whichreceivedEPA'sScienceAchievementAwardin2001.

1995 Region4Bulletins:RegionalRiskAssessmentGuidance AsanEPAtoxicologist,authoredRegion4riskbulletinsonToxicityAssessmentandonDevelopmentof

RemedialGoalOptions.

ADDITIONAL WORK IN TOXICOLOGY 2014-16DevelopmentofanAdverseOutcomePathwayDocumentforaMutagenicModeofActionforCancer Workedwithindividualsfrombothgovernmentandtheprivatesector,collaboratedonamanuscript

detailingthemodeofaction/adverseoutcomepathwayforlivertumorigenesisinanimalsandhumansbyaflatoxinB1,atoxinproducedbyfungiandubiquitousingrainsandgroundnuts.

2009-16OngoingScientificConsultationontheHealthEffectsofHexavalentChromium Providesongoingsupportfortoxicologicalandriskassessmentinformationfortoxicologicalissuesrelated

tohexavalentchromiumforaFortune100company.2010 StatisticalAnalysisofReproductiveEndpointsinRatsExposedtoFlameRetardantChemical PerformedstatisticalanalysisofdichotomousdataforreproductiveendpointstoinformaEuropean

consortiumaboutthemostappropriatemethodsfordataanalysis.2009 ResponsestoEPAChargeQuestionsforReviewofthe2009ToxicologicalReviewof1,4-Dioxane WroteresponsestoEPA's"ChargetoExternalReviewersfortheToxicologicalReviewof1,4-Dioxane”

relatedtouncertaintyanalysis,physiologically-basedpharmacokinetic(PBPK)modelingandBenchmarkDosemodeling.


January2018

2009 Physiologically-basedPharmacokineticModelsforMethylmercury,Arsenic,CadmiumandBisphenol-Aforuseasteachingtools

TranslatedexistingmodelsintotheBerkeleyMadonnacomputersoftwareforuseasteachingaidsforpersonnelattheAgencyforToxicSubstancesandDiseaseRegistry.

2008 WhitepaperontheEthicsofEnvironmentalRegulationandCompoundingConservatisminRiskAssessmentfortheOntarioMinistryoftheEnvironment

Usedhistoricalsources,philosophicalliteratureandmodernscientificpublicationstoprovideanunderstandingoftheextenttowhichenvironmentalregulationsandstandardsarebasedontheprecautionaryprinciple.

2008 AssessmentofConservatismofSoilandGroundwaterStandardsfortheOntarioMinistryoftheEnvironment

Assessedthelevelofconservatismofproposedenvironmentalmediastandardsusingstatisticalmethods.2007 ExpertPanelDevelopingaProtocolforToxicityTestingofaLegacyPesticideMIxture Servedonapaneltorefineaprotocolfortoxicitytestingofsoilconsideringbothindividualpesticide

isomersandmixtures.2004 ConsultationwithEPARegion4MercuryStudyGroup AsanEPAtoxicologist,providedinformationtoagroupofRegion4personneltoaddressanewspaper

editorialregardinghumanhealthandmercury.

PeerReviewsandPeerConsultations2018 RegulatoryToxicologyandPharmacology,GioB.Gori,Editor,“BiomonitoringEquivalentsforCyanide”2017 EnvironmentInternational,LesaAylward,Editor,“Ananalysisofcumulativerisksbasedonbiomonitoring

dataforsixphthalatesusingtheMaximumCumulativeRatio”2017 ToxicologicalSciences,WilliamH.Farland,Assoc.Editor,“Identificationofnoveluncertaintyfactorsforhealth

hazardandriskassessment:Applicationtocleaningproductingredients”2097 EnvironmentInternational,LesaAylward,Editor,“ExcretionofDi-2-ethylhexylPhthalate(DEHP)Metabolites

inUrineisRelatedtoBodyMassIndexBecauseofReverseCausality”2017 RiskAnalysis,L.AnthonyCox,Editor,“CumulativeLow-DoseResponseAssessment:AnEmergentModelFor

Carcinogens,Noncarcinogens,AndMixtures”2017 EnvironmentInternational,LesaAylward,Editor,“Ananalysisofcumulativerisksbasedonbiomonitoringdata

forsixphthalatesusingtheMaximumCumulativeRatio”2017 RegulatoryToxicologyandPharmacology,GioBataGori,Editor-in-Chief,“GuidelinesforPerforming

SystematicReviewsintheDevelopmentofToxicityFactors”2017 RiskAnalysis,TonyCox,Editor-in-chief,“CumulativeLow-DoseResponseAssessment:AnAutocorrelatedFirst-

OrderModel”2017 ChemicalResearchinToxicology,F.PeterGuengerich,AssociateEditor,“Identificationofpotentialaryl

hydrocarbonreceptorligandsbyvirtualscreeningofindustrialchemicals"2016 CombinatorialChemistry&HighThroughputScreening,RathnamChaguturu,Editor,“ABigData

ApproachwithArtificialNeuralNetworkandMolecularSimilarityforChemicalDataMiningandIn-SilicoToxicityPrediction”

2016 ScienceoftheTotalEnvironment,Dr.JayGan,Editor,“Occurrence,SourcesandEstimationofAir-SoilExchangeofPolychlorinatedbiphenylsinIndiancities”

2016 ScientificResearchandEssays,Dr.N.J.Tonukari,Editor,“BayesianAnalysistoDetectChange-pointinTwo-PhaseLaplaceModel”

2016 EnvironmentalScienceandTechnology,Dr.BeateEscher,Assoc.Editor,“ToxicogenomicsofDevelopmentalToxicityof6-OH-BDE47inChickenEmbryo"


January2018

2016 EnvironmentalHealthPerspectives,Dr.MartinVandenBerg,Assoc.Editor,“Definingtheneurotoxicpotentialofnondioxin-likepolychlorinatedbiphenylspresentinfishfromUSlakesusingaryanodinereceptor-basedequivalencyscheme”

2016 ScienceoftheTotalEnvironment,Dr.JayGan,Editor,“Occurrence,SourcesandEstimationofAir-SoilExchangeofPolychlorinatedbiphenylsinIndiancities"

2015 Structuredpeerreviewofacomparisonbetweentheeffectsoftobaccosmokeandnicotinevaporfrommodifiedrisktobaccoproductsonthelungsofmice

Answeredaseriesofchargequestionsandalsoprovidedsuggestionforfutureresearch.2015 EnvironmentalHealthPerspectives,Dr.MartinVandenBerg,Assoc.Editor,“Definingtheneurotoxic

potentialofnon-dioxin-likePCBspresentinfishfromUSlakesusingaryanodinereceptor-basedequivalencyscheme.”

2015 IUMBLife,Dr.AngeloAzzi,Editor,“IdentificationofdifferentiallyexpressedthreenoveltranscriptvariantsofmouseArntgene.”

2015 EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“Antioxidantactivityasapotentialmechanismexplainingthenegativeinfluenceofleadandcadmiumonworkingmemoryduringaging.”

2015 ToxicologicalandEnvironmentalChemistry,Dr.SamKacew,Editor,“Headspaceandsmallchamberstudiesofairbornediacetylreleasefromselectedfoodflavoringmixtures:Activitycoefficientsandairmodelingimplications”

2015 EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“Transcriptomicandvisualgene-networkanalysisofsilvernanoparticlespotentiallyinducedAlzheimer'sdiseaseprogressioninmousebrainneuralcells”

2015 EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“IdentificationofFreePhthalateMetabolitesinHumanCerebrospinalFluid.”

2014 CriticalReviewsinToxicology,Dr.RogerO.McClellan,Editor,“Riskassessmentsforchronicexposureofchildrenandprospectiveparentstoethylbenzene(CASNo.100-41-4)"

2014 EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“Impactofearly-lifebisphenolAexposureonprecorticaldopamineandserotoninsystemsinjuvenileandadultmalerats.”

2014 EnvironmentalResearch,Dr.JoseL.Domingo,Editor,“BisphenolAisassociatedwithinsulinresistanceandmodulatesadipokinesgeneexpressioninobesechildren.”

2014 HumanandExperimentalToxicology,Dr.KaiSavolainen,Assoc.Editor,“GlobalMethaemoglobinaemiaResearchOutput(1940–2013):ABibliometricAnalysisBasedonScopusDatabase."

2014 HumanandExperimentalToxicology,Dr.A.WallaceHayes,Assoc.Editor,“PharmacokineticStudyofOmeprazoleanditsMetabolitesinMalesandFemales,FemalesExposedtoHigherLevelsofOmeprazole.”

2013 ConsultationtoaWaterUtilityRegardingtheQualityofWaterProvidedtoaCommunity Providedinitialconsultationandcoordinatedapeerreviewofariskassessmentofthepesticide

toxapheneoccurringintraceamountsinthewater.2013 HumanandEcologicalRiskAssessment,Dr.BarryJohnson,Editor,“AssessmentofSoilScreeningLevels

duetoAccidentalIngestionofChryseneandBenzo[k]fluorantheneatIran’sTORSite.”2012 HumanandExperimentalToxicology,Dr.A.WallaceHayes,Editor.“Effectofnicotinepre-treatmenton

arsenicinducedoxidativestressinWistarrats."2012 HumanandExperimentalToxicology,Dr.A.WallaceHayes,Editor,“ElementalimpuritiesinNigerian

pediatricsyrups:Mercuryinviolationofstandardguidelines."2011 JournalofToxicologyandEnvironmentalHealth,Dr.SamKacew,Editor,“ScreeningLevelRisk

AssessmentforSANTrimerDetectedinSoilandGroundwater”2011 HumanandEcologicalRiskAssessment,Dr.BarryJohnson,Ed.“MonteCarloSimulation-basedHealth

RiskAssessmentofHeavyMetalPollution-ACaseStudyintheQixiaMiningArea,China”2011 RiskAnalysis,Dr.TonyCox,Editor,“AGradientMarkovChainMonteCarloAlgorithmforComputing


January2018

MultivariateMaximumLikelihoodEstimatesandPosteriorDistributions:MixtureDoseResponseAssessment”

2010 EnvironmentalResearch,EllenSilbergeld,Ed.“StructuralNeuroimagingEvaluationofAdultswithChildhoodLeadExposure”

2010 HumanandExperimentalToxicology,Prof.KaiSavolainen,EditorinChief.“TheWorldLibraryofToxicology,ChemicalSafetyandEnvironmentalHealth(WLT)”

2010 JournalofExposureScienceandEnvironmentalEpidemiology,Dr.NatalieFreeman,Assoc.Ed."Comparisonofatoxicokineticandaquestionnaire-basedapproachtoassessmethylmercuryintakeinexposedindividuals”

2010 EnvironmentalResearch,Dr.EllenSilbergeld,Ed.“VaryingcoefficientfunctionmodelstoexploreinteractionsbetweenmaternalnutritionalstatusandprenatalmethylmercurytoxicityintheSeychellesChildDevelopmentNutritionStudy”

2009 RegulatoryToxicologyandPharmacology,GioBattaGori,Ed."DerivedReferenceDoses(RfDs)fortheEnvironmentalDegradatesoftheHerbicidesAlachlorandAcetochlor:ResultsofanIndependentExpertPanelDeliberation"

2009 EnvironmentalResearch,EllenSilbergeld,Ed."EnvironmentalPolicyandChildren'sHealthinMexico"2009 ToxicologicalSciences,Dr.JohnLipscomb,Assoc.Editor,"Age-,Dose-andTime-DependencyofPlasma

andTissueDistributionofDeltamethrininImmatureRats."2009 Chemosphere,HeideloreFiedler,Ed."Quantitativestructure-activityrelationship(QSAR)studiesfor

predictingactivationoftheryanodinereceptortype1channelcomplex(RyR1)bypolychlorinatedbiphenyl(PCB)congeners"

2009 EnvironmentalResearch,EllenSilbergeld,Ed."DeterminationofbromadioloneresiduesinfoxfaecesbyLC/ESI-MSinrelationshipwithtoxicologicaldataandclinicalsignsafterrepeatedexposure.”

2008 Chemosphere,HeideloreFiedler,Ed."TissueDistributionofPolychlorinatedBiphenylsandEffectsonAlaskanNorthernFurSealsAssessedwithFiveCongenerClassificationSchemes"

2008 Chemosphere,HeideloreFiedler,Ed."LevelsofPolychlorinatedDibenzo-p-dioxins,Dibenzofurans,andBiphenylsinSouthernMississippiCatfishandEstimationofPotentialHealthRisks"

2007 CriticalReviewsinToxicology,RogerO.McClellan,Ed.“RiskAssessmentofToxapheneanditsBreakdownProducts:TimeforaChange”

2006 EnvironmentalForensics,IoanaPetrisor,Ed.“IdentifyingMetalsContaminationinGroundwaterUsingGeochemicalCorrelationEvaluation”

2002 EnvironmentalScienceandTechnology,MitchellJ.Small,Ed.“Whyandhowshouldweassessoccupationalhealthimpactsinintegratedproductpolicy?”

2001 OhioEnvironmentalProtectionAgency,“HumanHealthRiskAssessmentConceptPaper”2000 ToxicologyExcellenceinRiskAssessment,“LifetimeEstimateofSkinCancerRiskfromuseofCoalTar

ContainingShampoos”1999 EnvironmentalScienceandTechnology,MitchellJ.Small,Ed.“ChlordaneUptakeanditsTranslocationin

FoodCrops”1997 AgencyforToxicSubstancesandDiseaseRegistry,“PublicHealthInterventionstoPreventorMitigate

PossibleAdverseHealthEffectsRelatedtoMethylParathionPesticideExposure”1995 NationalResearchCouncil,“HumanHealthPreliminaryRiskEvaluationoftheJinkampoIncinerator

ComplexActivitiesintheNavalAirFacility,Atsugi,Japan”

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