Are you experiencing fatigue and low or no sex drive?

Do you have less mental focus?

Do you have less tolerance to stress and feel down?

Is your body getting softer while you are gaining fat?

Have you been exercising for months or years

without improvements in your body?

Do you want to have healthy testosterone Levels but are afraid to use it?

You may be one of the 13 million men in the United States that are suffering from testosterone deficiency but who are suffering needlessly.

There is hope…

Read “Testosterone: A Man’s Guide”

Available Here

Testosterone: Target OrgansTestosterone: Target OrgansTestosterone: Target OrgansTestosterone: Target Organs

brainbrainlibido, moodlibido, moodskinskin

hair growth, balding, sebum production

musclemuscleincrease in strength and volume

liverliversynthesis of serum proteins kidneykidney

stimulation of erythropoietin production

male sexual male sexual organsorganspenile growthspermatogenesisprostate growth and function

bone marrowbone marrowstimulation of stem cells

boneboneaccelerated linear growthclosure of epiphyses

Albumin-bound T38%

Free T2%

SHBG-bound T60%T = testosterone

Only 2% is free testosteroneand 98% is bound

Testosterone Fractions in the Blood

Hourly Testosterone Blood Levels in Healthy Young and Older Men in

a Day

Source: Bremner WJ, Vitiello MV, Prinz PN., J Clin Endocrinol Metab 1983;56:1278-1281

000020001600120008000400

0000

Testosterone Deficiency Testosterone Deficiency (Hypogonadism)(Hypogonadism)

Normal levels in blood:Normal levels in blood: Men... Total test. 300-1100 ng/dL, Men... Total test. 300-1100 ng/dL,

Free test. 5 - 21 ng/dLFree test. 5 - 21 ng/dL

Women... Total test. 10-50 ng/dLWomen... Total test. 10-50 ng/dL

Free test. 0.10-0.85 ng/dLFree test. 0.10-0.85 ng/dL Symptoms of testosterone deficiency:Symptoms of testosterone deficiency:

Fatigue, low or lack of sex drive, Fatigue, low or lack of sex drive, poor appetite, loss of muscle mass & poor appetite, loss of muscle mass & strength, depressionstrength, depression

Signs and Symptoms of Low Testosterone

Loss of muscle mass and strength Loss of muscle mass and strength Loss of libido and erectile dysfunctionLoss of libido and erectile dysfunction Depression Depression Lethargy (fatigue, lack of focus)Lethargy (fatigue, lack of focus) Osteoporosis (bone loss)Osteoporosis (bone loss) Some regression of secondary sexual Some regression of secondary sexual

characteristics (body hair loss, etc)characteristics (body hair loss, etc) Oligospermia or azoospermia (low or no Oligospermia or azoospermia (low or no

sperm count)sperm count)

Tenover JL. Endocrinol Metab Clin North Am. 1998;27:969-987Petak SM, et al. AACE Clinical Practice Guidelines. Available at: http://www.aace.com/clin/guides/hypogonadism.html

Causes of Hypogonadism Causes of Hypogonadism (Low Testosterone Blood (Low Testosterone Blood

Level)Level) Congenital hypogonadismCongenital hypogonadism Primary testicular failurePrimary testicular failure Hypogonadotropic hypogonadismHypogonadotropic hypogonadism Severe systemic disease, including HIV infectionSevere systemic disease, including HIV infection Normal agingNormal aging Medications: ketoconazole, glucocorticoids, Medications: ketoconazole, glucocorticoids,

spironolactone, cimetidine, phenytoin, spironolactone, cimetidine, phenytoin, flutamide, megesterolflutamide, megesterol

Testosterone Options

Testosterone Metabolites and Their Functions

Testosterone5-7

mg/day

Androgen

Receptor

Androgen

Receptor

EstrogenReceptor

Dehydro Testosterone(DHT) (by 5α-reductase)

Estradiol (by aromatase)

Direct Effect

LH

Oxidation by LiverElimination by Kidneys

Skin, Prostate

Hair, Brain, Bone

Muscle, Brain

Potential Side Effects

Polycythemia

Benign Prostatic Hypertrophy

Acne

Gynecomastia

Increased BP

TRT Benefits

sexual function

Mentalfocus

Stamina and Bone Strength

LeanBodyMass

For More Information:

TestosteroneWisdom.com