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The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather J. Spence, Xinzi Yu, Ireen König, Kurt Anderson, Laura M. Machesky Current Biology Volume 20, Issue 4, Pages 339-345 (February 2010) DOI: 10.1016/j.cub.2009.12.035 Copyright © 2010 Elsevier Ltd Terms and Conditions

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Page 1: The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather

The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion 

Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather J. Spence, Xinzi Yu, Ireen König, Kurt Anderson, Laura M. Machesky  

Current Biology Volume 20, Issue 4, Pages 339-345 (February 2010)

DOI: 10.1016/j.cub.2009.12.035

Copyright © 2010 Elsevier Ltd Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather

Figure 1

Current Biology 2010 20, 339-345DOI: (10.1016/j.cub.2009.12.035) Copyright © 2010 Elsevier Ltd Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather

Figure 2

Current Biology 2010 20, 339-345DOI: (10.1016/j.cub.2009.12.035) Copyright © 2010 Elsevier Ltd Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather

Figure 3

Current Biology 2010 20, 339-345DOI: (10.1016/j.cub.2009.12.035) Copyright © 2010 Elsevier Ltd Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: The Actin-Bundling Protein Fascin Stabilizes Actin in Invadopodia and Potentiates Protrusive Invasion Ang Li, John C. Dawson, Manuel Forero-Vargas, Heather

Figure 4

Current Biology 2010 20, 339-345DOI: (10.1016/j.cub.2009.12.035) Copyright © 2010 Elsevier Ltd Terms and Conditions

http://www.elsevier.com/termsandconditions

HANAU WIDE-VUE ARCON ARTICULATORS AND … 30˚ Condylar Guidance Protrusive Calibration Closed Track-20˚ Protrusive Inclination Fixed Centric Stop 4 PROTRUSIVE-RETRUSIVE FIG. 4 Thumbscrew

BK001 Actin Binding Protein Biochem Kit (Muscle Actin ...BSA01-001 General actin buffer BSA02-001 Actin polymerization buffer BSA03-001 F-actin cushion buffer BSA04-001 ATP stock BSEG-01

Crenactin forms actin-like double helical filaments regulated by … · F-actin homologue of any other actin-like filament investigated to date. In F-actin, the double helix is stabilised

Actin in Axons: Stable Scaffolds and Dynamic Filamentsgrowthcones.neuroscience.umn.edu/Letourneau_PDF_files_files/Actin-in-axons.pdfof actin filaments in mature axons is to create

actin troponin actin troponin tropomyosin actin troponin tropomyosin

A crosslinked and ribosylated actin trimer does not ... · 66 ribosylation of actin monomers on the binding of actin binding proteins, including myosin. They 67 found that G-actin

Dense fibrillar collagen is a potent inducer of invadopodia via a

Chapter 3 The Connection Between Actin ATPase and ...actin/documents/TheConnection... · The Connection Between Actin ATPase and Polymerization ... Actin–actin interactions are

Actin Polymerization - Cytoskeleton · See Figure 1 for a typical positive control pyrene actin polymerization reaction. VI: Actin Polymerization/Depolymerization Studies . cytoskeleton.com

Microfilament Actin 1

Invadopodia: proteolytic feet of cancer cellsjournals.tubitak.gov.tr/biology/issues/biy-14-38-6/biy-38-6-4-1404-110.pdf · invadopodia. While presenting the upstream signaling events

G-actin / F-actin In Vivo Assay Kit - · PDF fileactin protein according to the G-actin/F-actin In Vivo Assay Kit instructions. ... cytoskeleton.com cytoskeleton.com Page 9 A) Notes

12. Centric & Protrusive Record

Hierarchical self-assembly of actin bundle networks: Gels …safinyaweb/PDFs/publications_PDF/2005...globular actin G-actin, molecular weight MW =42 kDa form or as actin filaments

CYTOSKELETON NEWS - fnkprddata.blob.core.windows.net · Dynamic remodeling of the actin cytoskeleton [i.e., rapid cycling between filamentous actin (F-actin) and monomer actin (G-actin)]

Invadopodia and Podosomes

Actin and Myosin

Podosomes and Invadopodia

Rlr m2 actin

Rachis dégénératif Pathologie discale protrusive Canal étroit...Pathologie discale protrusive Canal étroit F. Lecouvet, X. Banse, V. Perlepe, T. Kirchgesner, S. Acid J. Malghem,

Fluorescent Gelatin Degradation Assays for Investigating Invadopodia Formation

Interactions between Actin, Myosin, and an Actin-binding Protein … · 2002-12-26 · 5707 erythrocyte spectrin with an actin-like protein (12), makes the actin-binding protein a

Vinculin–actin interaction couples actin retrograde flow ...lpmt.biomed.uni-erlangen.de/mediafiles/Publications/Thievessen JCB... · dynamics with fast F-actin ... Here we report

Bilder.2 Actin

Evidence That an Unconventional Actin Can Provide ... · Evidence That an Unconventional Actin Can Provide Essential F-Actin Function and That a Surveillance System Monitors F-Actin

RESEARCHARTICLE Actin-MediatedGeneExpressionDependson ... · RESEARCHARTICLE Actin-MediatedGeneExpressionDependson RhoAandRac1SignalinginProximalTubular EpithelialCells KlaudiaGiehl1,ChristofKeller2,SusanneMuehlich3

QCMTM Gelatin Invadopodia Assay (Green)

Interactions of Elongation Factor 1 with F-Actin and ... · colocalizes with -actin mRNA and F-actin in protrusions of chicken embryo fibroblasts and ... links actin filaments via

F Actin Visualization Biochem Kit - Cytoskeleton · actin (G-actin) can self assemble (polymerize) into microfilaments (F-actin), the fundamental unit of the actin cytoskeleton. Actins

CHANGES IN THE ACTIN CYTOSKELETON AND ACTIN · PDF fileChanges in the Actin Cytoskeleton and Actin-associated Proteins in HeLa Cells as a Result of E. coli O157:Н7... 157 pattern

The interplay between the proteolytic, invasive, and ...€¦ · Review Preface Invadopodia are actin-based protrusions of the plasma membrane that penetrate into the extracellular

Actin Polymerization - Cytoskeleton

ACTIN DEPOLYMERIZING FACTOR4 Regulates Actin …ACTIN DEPOLYMERIZING FACTOR4 Regulates Actin Dynamics during Innate Immune Signaling in ArabidopsisW OPEN Jessica L. Henty-Ridilla,a,1

Review Actin-targeting natural products: structures ... · actin-binding proteins actively break or ‘sever’ actin filaments [e.g. actin-depolymerizing factor (ADF) and cofilin]

Lecture 3 Actin and myosin in non-muscle cells; Cell motility Outline: Actin polymerization in vitro Regulation of actin dynamics in cells Actin organization