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Page 1: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 2: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 3: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

The Adaptive Optics Main Components

Page 4: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

Observer

Correct wavefront using

deformable optics

Measure residual wavefront

using a sensor

Calculate control parameters

Page 5: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

Imagine Eyes

Page 6: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 7: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 8: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

Not all Zernike Terms are Weighted Equally. The more peripheral terms have lesser impact on visual performance, while the

more centrally located ones have a greater contribution

Page 9: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 10: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

•  10 subjects

•  Dominant Eye

•  Inclusion Criteria:

clear intraocular media

no ocular diseases /no previous surgeries

age ranged from 25 to 35 years

Page 11: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 12: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

True Accommodation

Physiologic changes

Page 13: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

Accommodation - check

Page 14: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 15: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 16: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 17: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 18: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 19: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 20: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

Subjects(N)

Age(years) GenderSE(D)

HOARMS

Trefoilµm

Comaµm

SphAbµm

10 30±28male2female ‐1.05±1.5 0.34±0.10 ‐0.15±0.14 0.07±0.14 0.11±0.10

* 6-mm pupil

Page 21: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

num

ber

of

lett

ers

induced defocus

Corr

DOF

DOF middle point

Page 22: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

0

2

4

6

8

10

12

‐3 ‐2 ‐1 0 1 2 3 4

corr

Trefoil+0.3

Coma+0.3

num

ber

of

lett

ers

induced defocus

Page 23: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

num

ber

of

lett

ers

induced defocus

Corr

num

ber

of

lett

ers

induced defocus

num

ber

of

lett

ers

induced defocus

Page 24: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

3.7D Baseline (sphere corr.)

4.0D 0.3µm coma

3.5D 0.3µm trefoil

4.5D 0.3µm SA

6.0D 0.6µm SA

5.9D 0.9µm SA

-0.3µm SA 5.2D

-0.6µm SA 6.0D

-0.9µm SA 5.2D

(D)

-6 –5 –4 –3 –2 –1 0 1 2 3 4 5 6 7

Page 25: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

The depth of focus curve (blue curve) strongly increased (up to 2D), but there are a maximum before a decrease for strong values (0.9µm).

mag

nitu

de -

DO

F

magnitude spherical aberration (SA)

Page 26: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes

The best focus point (pink curve) was continuously shifted (~2.7D/µm).

mag

nitu

de -

DO

F

magnitude spherical aberration (SA)

Page 27: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes
Page 28: The Adaptive Optics Main Componentsvoi.opt.uh.edu/48_Rocha_HOAonDepthofFocus.pdfdeformable optics Measure residual wavefront using a sensor Calculate control parameters . Imagine Eyes