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Page 1: THE BIOLOGICAL EFFECTS OF RADIATION - …webfiles.ehs.ufl.edu/rssc_biological_effects_ionizing_rad.pdfThe radiation may damage the cell, but the cell repairs the damage; 3. ... THE

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Four things can happen when radiation enters a cell:

1. The radiation may pass through without any damage occurring;

2. The radiation may damage the cell, but the cell repairs the damage;

3. The radiation may damage the cell…the damage is not repaired…and the cell

replicates itself in the damaged form;

4. The cell dies.

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Hematologic Syndrome

Prodromal Stage: Mild symptoms appear within a few hours and last for several days

Latent Period: May last up to 4 weeks

Manifest Illness: Vomiting, diarrhea, fatigue and fever – Decline in blood cells –

Recovery in 2 to 4 weeks…May last up to 6 months

Possible death due to infection, dehydration or hemorrhage

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Gastrointestinal Syndrome

Prodromal Stage: Vomiting and diarrhea occur within hours and last up to one day

Latent Period: Lasts 3-5 days

Manifest Illness: Nausea, vomiting and diarrhea – Worsens to bloody stools

Death within 4 to 10 days after exposure primarily due to intestinal cell damage –

Also damage to blood-forming tissue results in hemorrhaging and dehydration.

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Central Nervous System Syndrome

Prodromal Stage: Severe nausea and vomiting within a few minutes – Nervousness,

confusion, burning skin, vision loss…possible loss of consciousness

Latent Period: May last up to 12 hours, or not at all

Manifest Illness: Disorientation, loss of muscle control, breathing problems, seizures,

coma

Death always within a few days of exposure – due to increased fluid in brain

(pressure) – Death occurs before hematologic and gastrointestinal symptoms appear

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