From the lipstick prints of a well-wisher visible on Dr. Larry Norton’s right cheekto Evelyn Lauder and René Syler’s convivial emcee exchanges, the October 18thSymposium and Awards Luncheon of The Breast Cancer Research Foundation(BCRF) had a celebratory feel.

And with good reason. First, the Luncheon, attended by more than 1,070 people,raised over $1.7 million. The Foundation awarded a record $22 million in grantsto 110 researchers studying the disease at major academic medical centers acrossthe United States and in seven countries abroad, in what Lauder described as “theAcademy Awards of Medicine” — the BCRF founder’s witty recognition of thecaliber of breast cancer researchers receiving grants.

Then there was the status of breast cancer research and treatment itself. Norton,scientific director and chairman of BCRF’s Medical Advisory Board, described it:“We can see a finish line now.” Norton reminded the audience during the openingremarks of BCRF’s morning Symposium at Manhattan’s Waldorf=Astoria Hotelthat celebration of what we have collectively accomplished is appropriate, as longas we maintain stamina for completing the race. (Continued on page 2)

BCRF’S SYMPOSIUM AND LUNCHEONBreast Cancer Now Versus Then

The Breast Cancer Research Foundation

PINK PRESSWin

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2006

A Message from Evelyn Lauder, Founder and ChairmanYou will be delighted to know that The BreastCancer Research Foundation is truly at the forefront of major news in breast cancer researchadvances. BCRF grantees are working together,sharing ideas to use resources effectively and maximize results. Having already supported the NCI-directed clinical trials cooperative groupsaround the U.S. for a number of years, theMedical Advisory Board led us to adopt two newcollaborative projects this year:

First, our funds have provided founding support forthe Breast Cancer Research Consortium, representing leading researchers from top medical centers across the U.S. to speed clinical trials evalu-ating new cancer treatments. The Consortium willconduct tests of new drugs in all stages of breastcancer, including trials of promising preventivetreatments. These tests will emphasize the biologyand genetics of breast cancer and will draw connections between the molecular biology of thetumor and the response to new classes of drugs.

The Consortium will also design new clinical trials, emphasizing “pre-operative” testing inwomen before surgery and trials measuring the

growth of tumors, bloodvessels and the metabo-lism of cancer cells. Thisis the first group of itskind sustained withoutgovernment funding andwe hope BCRF’s continuing support willattract other donors.

Secondly, a pilot BCRFgrant is bringing togethertwo of the world’s largestcooperative organizations

for breast cancer clinical trials: The Breast CancerIntergroup of North America and the BreastInternational Group. With BCRF funding, members of both groups have begun a truly global collaboration aimed at integrating their respectivescientific programs, and cooperative planning ofclinical trials and treatment. They first met inDecember 2005, in conjunction with the SanAntonio Breast Cancer Symposium.

How thrilling it is to be fostering such historicalliances so we can help advance the frontiers ofmedical research. We are ever grateful for yourcontributions to our efforts as we race towards ourgoal of prevention and a cure. We’d like to be thefirst at the finish line.

Evelyn Lauder, Laura Lassman, Myra Biblowit, René Syler

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Winter Newsletter 2006 3The Breast Cancer Research Foundation2

Evelyn Lauder and William Lauder

symposium and luncheon

Linda Lindenbaum and Renée Belfer

(Breast Cancer Now Versus Then Continued)

Now in its twelfth year of funding research in breast cancer, BCRF recognized quality-of-life researcher Patricia Ganz, MD, with the 2005 Jill Rose Award. The award, establishedten years ago, honors outstanding scientific research and the legacy of the late Jill Rose, aBCRF founding member. Ganz is an oncologist who directs the Division of CancerPrevention & Control Research at UCLA’s Jonsson Cancer Center where she leads thePatients and Survivors Research Program. She has pursued quality-of-life research since,as she said, “the days when it was really unconventional to do so.” That was 20 years ago.Because of her research, clinicians may guide their patients into the post-treatment phasewith greater support and appropriate expectations. On accepting the award Ganz told theaudience, “it is a privilege to practice medicine,” and that her role as an oncologist hashelped her better understand life after breast cancer.

First Lady of New York State Libby Pataki recognized the renowned artist Chuck Closewith BCRF’s Humanitarian Award. Close said modestly upon acceptance of the awardthat his wife, a breast cancer survivor, and other survivors, are the heroes who are moredeserving of recognition.

At every turn of the day’s events researchers and survivors described how different theprospects are for patients with breast cancer today as a result of research advances overthe past decade. In a poignant video produced by Brian Litman and introduced by BCRFpresident Myra Biblowit, survivors and their families underscored the impact of improvedtreatments and better outcomes. With the message of accomplishment in the ongoing faceof hope, another message was also clear: the strides of research could not have beenachieved without the foresight and support of BCRF.

The Symposium and Luncheon were made possible by underwriters Roslyn and LeslieGoldstein and longstanding corporate sponsor, Roche. The Foundation also thanksBenefit Co-Chairs Anne Eisenhower Flöttl, Betsy Green, Ronnie Heyman, Gail Hilson,Evelyn Lauder, Gigi Mortimer, and Elizabeth Rohatyn.

Sue-Ann Friedman and Roslyn Goldstein

Jane Lauder, Jamee Gregory,Jo Carole Lauder Gail Hilson

Marshall Rose, Dr. Patricia Ganz,Wendi Rose Susan RudinLibby Pataki and Chuck Close Leonard Lauder

Dr. Funmi Olopade and Dr. Laura Esserman

1 LB Manjari Chocolate2 OZ Butter3 OZ Sugar14 Egg Whites(Serves 15)

Combine the chocolate and butter in a saucepan and melttogether over low heat; set aside.

In a separate bowl, combine the sugar and egg whites. Whisk orbeat on high speed until the egg whites form stiff peaks to forma meringue.

Fold the meringue mixture quickly into the melted chocolate andrefrigerate for several hours. Enjoy!

Waldorf=Astoria Hotel’s Chef Jean-Claude Perennou’s Low-Fat Chocolate Mousse Recipe

Molly Wallace and Cynthia Shipper

Myra Biblowit, Evelyn Lauder, Dr. Larry Norton. Front row: Dr. Patricia Ganz, Dr. Pamela Goodwin, Dr.Annette Stanton,Dr. Electra Paskett, Dr. Edith PerezU

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The Breast Cancer Research Foundation Winter Newsletter 20064 5

Dear Friends:

In October we awarded $22 million to 110 researchers, our largestgrant-making program ever. We now fund investigators at renownedmedical centers in the United States, Canada, Europe, Israel and LatinAmerica. The Breast Cancer Research Foundation’s mission of preven-tion and a cure for breast cancer in our lifetime has truly become a worldwide effort.

Just as the research we fund is critical, spreading the word about the importance ofresearch is vital to BCRF’s growth. One of the most effective ways we can impact thehealth of men and women across the globe is to enlighten people about the Foundation’swork. This fall the BCRF staff spoke to employees at Coach, Movado, Song, and KarenNeuburger, encouraging them to join us in our mission. We have reached out to the nextgeneration with college fundraising programs and held our first Junior event, attractingover 300 young New Yorkers eager to support a cause that touches so many. This fall theFoundation was honored with inaugural events in Lexington, Kentucky, and in Boston,Chicago and Toronto. Through Play for P.I.N.K. tournaments and Danskin Triathlonswe reach over 100,000 people nationwide. Our network of BCRF ambassadors contin-ues to grow. Wherever we go, I am moved by how people are impacted by this diseaseand what motivates them to give back.

Our donors around the world, so generous in spirit and deed, truly are the engine thatfuels The Breast Cancer Research Foundation. At this moment in time, when research isadvancing at an unprecedented pace, when there is a renaissance of biomedical science,the investments that BCRF makes are having an enormous impact on every continent.To all of you who have helped us tell our story to new audiences, thank you for beingour ambassadors. Your enthusiasm, your commitment and your support translate into abrighter future for women everywhere.

Sincerely,

Myra J. BiblowitPresident

LETTER FROM OUR PRESIDENT

José Baselga, MD, Chairman of Medical Oncology and Professor of Medicine at Valld'Hebron University Hospital in Barcelona, Spain, was named President-Elect of theEuropean Society of Medical Oncology (ESMO). Dr. Baselga also received the 2005 ESMOAward for his "outstanding contribution in the field of medical oncology."

H. Shelton Earp III, MD, Director of the Lineberger Comprehensive Cancer Center andProfessor of Medicine and Pharmacology at the University of North Carolina, was namedPresident of the Association of American Cancer Institutes.

Gabriel N. Hortobagyi, MD, FACP, Chairman of the Department of Breast MedicalOncology and Professor of Medicine at the University of Texas, MD Anderson CancerCenter, was named President-Elect of the American Society of Clinical Oncology (ASCO).

Olufunmilayo (Funmi) Olopade, MB, BS, FACP, founding director of the Center forClinical Cancer Genetics and Professor of Medicine and Human Genetics at the Universityof Chicago Medical Center, was awarded a MacArthur Foundation Fellowship, a prestigiousfive-year grant presented to 25 "individuals who show exceptional merit and promise for continued and enhanced creative work."

Geoffrey M. Wahl, PhD, Professor at the Salk Institute, was named President-Elect of theAmerican Association for Cancer Research (AACR).

CONGRATULATIONS TO BCRF RESEARCHERS…

about us

“We’ve changed the natural history of breast cancer through better detection andtreatment,” said Pamela Goodwin, MD, Professor of Medicine, Mt. Sinai Hospital,University of Toronto. Her remark as a panelist at the scientific Symposium that preceded the annual BCRF Luncheon in October underscored the changes thatresearch has brought to breast cancer and complemented Jill RoseAwardee Dr. Patricia Ganz’s explanation of what question drives a newgeneration of research: “What is the impact of primary breast cancertreatments on women’s health?”

This year’s public Symposium panel consisted of five top, female breastcancer researchers including Ganz, an oncologist who heads the Divisionof Cancer Prevention & Control at UCLA’s Jonsson Cancer Center;Goodwin; Annette Stanton, PhD, Professor of Psychology andPsychiatry/Behavioral Sciences at UCLA; Electra Paskett, PhD,Professor of Cancer Research in the School of Public Health at OhioState University, and Edith Perez, MD, Professor of Medicine at MayoCollege of Medicine in Rochester, Minnesota.

In their nearly two-hour discussion followed by a Q & A session, the five scientists, ledby Ganz’s opening summary of the field of quality of life research, revealed importantinsights:

n Treatment for breast cancer has been shortened to 2-9 months over the past 20 years, but recovery often takes 2 years or more.

n Women are primarily concerned with the risk of death due to breast cancer, making them willing to undergo difficulties associated with long courses ofchemotherapy.

n Breast cancer patients are resilient women. However, high-risk groups include: young women whose fertility is jeopardized by treatment and women who lack family or social support while undergoing treatment.

n Remarkably, many patients experience measurable personal growth as a result of their cancer, reframing life priorities.

n Incremental return to pre-cancer activities is vital in the early survivorship stage.

CHANGE THE DISEASE, CHANGE THE SURVIVALQuality of life research center stage at public symposium, scientific retreat

scientific retreat

ADVISORY BOARD

Roberta M. AmonAndrea BronfmanMary BryantSusan Payson BurkeRena Rowan DamoneUte Dugan, MD, PhDSuzanne ElsonJanet FisherAnne Eisenhower FlöttlKim GarnerAmy P. Goldman, PhDMarjorie Reed GordonLorna Hyde Graev Betsy S. GreenBette-Ann GwathmeyLori HallRonnie HeymanGail HilsonSusan B. HirschhornRobin J. KemperKitty KempnerRochelle Kivell Sandra KrakoffSheila C. LabrecqueAmy LangerLaura LassmanEllen Levine Nancy NovogrodEllen Odoner, Esq.Mary Alice PappasAlexandra PenneyWinifred Gorlin PhillipsJane PontarelliLynda ResnickWendi RosePat RosenwaldValerie Salembier Suzanne SantryJudith P. SchlagerMuriel SiebertAnne Sitrick Ruth SpearLinda SteinErana StennettArlene TaubMissie R.TaylorWendy WassersteinKaren WebsterCathy WeinrothHarriet WeintraubSara Wolfensohn

BOARD OF DIRECTORS

Evelyn H. Lauder, ChairmanMyra J. Biblowit, PresidentJeanette S.Wagner, Vice PresidentDeborah Krulewitch,

Secretary and TreasurerCarolee FriedlanderCarlyn S. McCaffrey, Esq.Josie Robertson

BCRF MEDICAL ADVISORY BOARD

Chairman and Scientific DirectorLarry Norton, MD Memorial Sloan-Kettering Cancer Center

MembersNancy Davidson, MDJohns Hopkins University

Peter Greenwald, MD, Dr. PHNational Institutes of Health

Gabriel N. Hortobagyi, MDUniversity of Texas MD Anderson Cancer Center

Dr.Arnold Levine, Patricia Quick de Visscher,Francois de Visscher, Peg Mastrianni

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Winter Newsletter 2006 7The Breast Cancer Research Foundation6

scientific retreat

Kent Osborne, MD, of Baylor College of Medicine presented research findings describing the evolving under-standing of estrogen and progesterone receptors in helping doctors decide which drugs to use for breast cancer treatment. “Measuring the level of progesteronereceptors along with HER2 receptors may help to selectwhich type of endocrine therapy to use in individualizingtreatment,” he noted.

Also at the Retreat, Kathy Miller, MD, of Indiana School of Medicine, outlined her bioinformatics approach to under-standing how an individual’s genetic makeup predisposes her to success or failure with targeted drugs used to treat breastcancer — such as trastuzumab and bevacizumab. She suggested that this new information may help doctors prescribe thebest possible drug for treating breast cancer as well as form the basis for developing new targeted drugs.

BCRF’s Symposium and Retreat engaged scientific and non-scientific attendees alike in vigorous discussion about breastcancer as a collection of diseases with increasingly manageable outcomes. Dr. Norton observed that breast cancerresearch is revealing new insights in other areas of women’s health, such as heart disease, obesity, menopause and post-menopause. As quite a few attendees pointed out, the research gains of scientists in the U.S. and other developed nationssupported by BCRF must be translated across the globe. Breast cancer is international and its improved treatmentsshould be too.

Gail HilsonChairman

Roberta M. AmonJessie AraskogMuffie Potter AstonAnne H. BassCandice BergenMagda BleierMelinda BlinkenKatherine BryanSusan Payson BurkeCatherine CahillPatty CisnerosNorma DanaBeth Rudin DeWoodyBarbaralee Diamonstein-

SpielvogelRobin Chandler DukeHRH Princess Firyal

Anne Eisenhower FlöttlLorna Hyde GraevJamee GregoryAudrey GrussJoanne de GuardiolaMai Hallingby HarrisonDina Merrill HartleyGale Hayman-HaseltineVeronica HearstMarlene HessKaren M. KarpKitty KempnerEleanora KennedyCoco KopelmanJo Carole LauderKaren LauderKaren LeFrakWendy Vanderbilt LehmanMemrie M. Lewis

Nicole LimbockerCarol MackHillie MahoneyKetty MaisonrougeGrace T. MeigherLiz MezzacappaMuffy MillerNancy MissettGigi MortimerDeborah NorvilleLibby PatakiJean H. PearmanCarroll PetriePauline PittAnnette de la RentaJosie RobertsonPat RosenwaldHilary Geary RossChristine Hearst Schwarzman

Beverly SillsNancy SilvermanAnne SitrickDaisy Soros Louise M. SunshineFelicia TaylorJoan H.TischPatricia Quick de VisscherAdrienne VittadiniBarbara WaltersPatricia G.WarnerThorunn WathneHarriet WeintraubSaundra WhitneyVivien Wyser-PrattePaula Zahn

BCRF LEADERS COUNCIL

Goodwin explained that women’s weight is an indicator ofrecurrence. “Overweight and obesity have proven to be adversequalities in breast cancer,” she said. Her studies have revealedthat “insulin resistance syndrome” is a possible indicator thatbreast cancer risk and recurrence have increased. Goodwinadvocates greater awareness about weight as a risk factor andchanging lifestyle through food and exercise to reduce the risk.

Edith Perez, MD, described her project of tracking women taking the drug Herceptin for evidence of risk factors for cardiacdisease. “There is a small but real risk,” says Perez, “and now we

know how to carefully monitor and redirect those who will not respond well to the drug.”Perez and her colleagues made news in 2005, when the National Cancer Institute releasedthe results of two large clinical trials showing that Herceptin given with chemotherapyreduced recurrence of breast cancer in women with HER-2 positive breast cancer by 52percent. Perez was the principal investigator for one of those trials.

Stanton has helped identify “islands of disruption” that breast cancer survivors experi-ence. Her research extends Ganz’s findings in determining risk groups among survivors.“Breast cancer is not the same experience for all women,” said Stanton. “Women whoadopt an active approach to their experience fare particularly well, while others are atrisk for depression.” She and her colleagues focus on strategies for supporting survivorswith different psychological needs.

By sifting through the Young Breast Cancer Survivor Cohort Study to determine overlooked factors in breast cancer survival, Paskett has learned that nearly 30 percentsuffer chronic lymphedema—post-surgical swelling in the arms, due to removal of thelymph nodes in many breast cancer surgeries. Now, using data from the historicWomen’s Health Initiative Study, she is striving to understand how lymphedema mightbe prevented or reduced. “With such ahigh incidence of lymphedema in survivors,we must work on improving this chronic condition,” she told the audience.

Perez, Goodwin and Ganz were also amongthe five panelists at BCRF’s October 17thscientific Retreat. Now in its fourth year, theRetreat provides an opportunity for all current BCRF grantees to learn about theresearch of their colleagues the day prior tothe annual Luncheon and publicSymposium. Held at Memorial Sloan-Kettering Cancer Center, the Retreat has beenmade possible each year since inception by support from BCRF Advisory Board memberMuriel Siebert. In closing this year’s program, Larry Norton, MD, emphasized that, “thisannual gathering actually spawns new research collaborations.”

Treatment for breastcancer has been shortened to 2-9months over the past 20 years, but

recovery often takes2 years or more.

Dr. Eduardo Cazap, Dr. Carlos Arteaga, Dr. Gabriel Hortobagyi

Arlene Taub, Dr. Larry Norton, Muriel Siebert

Anne Eisenhower Flöttl, Myra Biblowit, Evelyn Lauder,Wolfgang Flöttl,Dr. Patrick Borgen

Dr.Albert Deisseroth, Betsy Green, Linda Stein

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Winter Newsletter 2006 9The Breast Cancer Research Foundation8

2005-2006 GRANTEES2005 - 2006 granteesStuart A. Aaronson, MDMount Sinai School of MedicineNew York, NY

D. Craig Allred, MDBaylor College of MedicineHouston, TX

Carlos L. Arteaga, MDVanderbilt University School ofMedicineThe First Step AwardNashville, TN

Jill Bargonetti, PhDHunter CollegeCity University of New YorkNew York, NY

José Baselga, MDVall d’Hebron UniversityHospitalBarcelona, Spain

Robert Benezra, PhDMemorial Sloan-KetteringCancer CenterThe Play for P.I.N.K. AwardNew York, NY

Jean-Yves Blay, MD, PhDCancéropôle Lyon Rhône-AlpesCentre Léon BérardLyon, France

Patrick I. Borgen, MD Memorial Sloan-KetteringCancer CenterNew York, NY

Jeffrey Boyd, PhDMemorial Sloan-KetteringCancer CenterNew York, NY

Powel H. Brown, MD, PhDBaylor College of MedicineHouston, TX

Joan S. Brugge, PhD Harvard Medical SchoolThe Arthur and Rochelle BelferFoundation AwardBoston, MA

Christophe Caux, PhDCancéropôle Lyon Rhône-AlpesCentre Léon BérardLyon, France

Eduardo Cazap, MDSLACOMLatin American-CaribbeanSociety of Medical OncologyBuenos Aires, Argentina

Jenny Chang, MD Baylor College of MedicineHouston, TX

Lewis A. Chodosh, MD, PhDAbramson Family CancerResearch InstituteUniversity of PennsylvaniaPhiladelphia, PA

Michael F. Clarke, MDStanford University School ofMedicineStanford, CA

Margot P. Cleary, PhDHormel InstituteUniversity of MinnesotaAustin, MN

Graham A. Colditz, MD,Dr.PHBrigham & Women’s HospitalHarvard Medical SchoolBoston, MA

Robert L. Comis, MDEastern Cooperative OncologyGroupCoalition of Cancer CooperativeGroupsPhiladelphia, PA

Andrew J. Dannenberg, MDWeill Medical CollegeCornell UniversityNew York, NY

Nancy E. Davidson, MDJohns Hopkins University Schoolof MedicineBreast Cancer Clinical TrialsConsortiumBaltimore, MD

Albert B. Deisseroth, MD,PhDSidney Kimmel Cancer CenterSan Diego, CA

Michael P. DiGiovanna, MD,PhDYale University School ofMedicineMade possible by RocheNew Haven, CT

H. Shelton Earp, MDUniversity of North Carolina Chapel Hill, NC

Matthew J. Ellis, MD, PhD Washington University School ofMedicineCancer and Leukemia Group BSt. Louis, MO

Laura J. Esserman, MD, MBAUniversity of California, SanFranciscoSan Francisco, CA

Zhen Fan, MDUniversity of TexasMD Anderson Cancer CenterHouston, TX

Judah Folkman, MDChildren’s Hospital & HarvardMedical SchoolBoston, MA

James M. Ford, MDStanford University School ofMedicineStanford, CA

Silvia Formenti, MD NYU School of MedicineNew York, NY

Harold P. Freeman, MDRalph Lauren Center for Cancer Care and PreventionNew York, NY

Patricia A. Ganz, MDUniversity of California, Los AngelesLos Angeles, CA

Judy E. Garber, MD, MPHDana-Farber Cancer InstituteBoston, MA

Teresa Gilewski, MDMemorial Sloan-KetteringCancer CenterThe Play for P.I.N.K. AwardNew York, NY

Pamela J. Goodwin, MD,MSc, FRCPCMount Sinai HospitalUniversity of TorontoToronto, Ontario, Canada

Julie R. Gralow, MDUniversity of WashingtonSouthwest Oncology GroupMade possible by Macy’sSeattle, WA

Lyndsay N. Harris, MDDana-Farber Cancer InstituteCancer and Leukemia Group BBoston, MA

Sandra L. Harris, PhDCancer Institute of New JerseyUniversity of Medicine &Dentistry of New JerseyThe Regina Quick AwardNew Brunswick, NJ

Gabriel N. Hortobagyi, MD,FACPUniversity of TexasMD Anderson Cancer CenterHouston, TX

Kathryn B. Horwitz, PhDUniversity of Colorado School ofMedicineDenver, CO

Alan N. Houghton, MD Memorial Sloan-KetteringCancer CenterThe Peter Jay Sharp FoundationAwardNew York, NY

Hedvig Hricak, MD, PhDMemorial Sloan-KetteringCancer CenterNew York, NY

Clifford Hudis, MDMemorial Sloan-KetteringCancer CenterNew York, NY

Mien-Chie Hung, PhDUniversity of TexasMD Anderson Cancer CenterHouston, TX

Stephen D. Hursting, PhD, MPHThe University of Texas atAustinAustin, TX

J. Dirk Iglehart, MDBrigham and Women's HospitalDana-Farber Cancer InstituteThe Arthur and Rochelle BelferFoundation AwardBoston, MA

Tan A. Ince, MD, PhDWhitehead Institute forBiomedical ResearchCambridge, MA

James N. Ingle, MDMayo Clinic - Rochester, MN Rochester, MN

Benita S. Katzenellenbogen,PhDUniversity of Illinois at Urbana-ChampaignUrbana, IL

Mary-Claire King, PhD New York Breast Cancer Study University of Washington Seattle, WA

Joshua LaBaer, MD, PhDHarvard Medical School The Arthur and Rochelle BelferFoundation AwardBoston, MA

Titia de Lange, PhDThe Rockefeller UniversityNew York, NY

Eva Y.-H P. Lee, PhDUniversity of California, IrvineIrvine, CA

Arnold J. Levine, PhDCancer Institute of New JerseyUniversity of Medicine &Dentistry of New JerseyThe Regina Quick AwardNew Brunswick, NJ

Ephrat Levy-Lahad, MDShaare Zedek Medical CenterJerusalem, Israel

Marc E. Lippman, MDUniversity of Michigan Ann Arbor, MI

Philip O. Livingston, MDMemorial Sloan-KetteringCancer CenterThe Play for P.I.N.K. AwardNew York, NY

Richard R. Love, MD, MSInternational Breast CancerResearch FoundationOhio State UniversityColumbus, OH

Joan H. Marks, MSNew York Breast Cancer StudySarah Lawrence CollegeBronxville, NY

John Mendelsohn, MDUniversity of TexasMD Anderson Cancer CenterHouston, TX

Sofia D. Merajver, MD, PhDUniversity of MichiganComprehensive Cancer CenterAnn Arbor, MI

Kathy D. Miller, MDIndiana University School ofMedicineMade possible by GenentechIndianapolis, IN

Hyman B. Muss, MDUniversity of VermontMade possible by RocheBurlington, VT

Katherine L. Nathanson, MDUniversity of PennsylvaniaThe Arthur and Rochelle BelferFoundation AwardPhiladelphia, PA

Larry Norton, MDMemorial Sloan-KetteringCancer CenterThe Peter Jay Sharp FoundationAwardNew York, NY

Paul M. Nurse, PhDThe Rockefeller UniversityNew York, NY

Kenneth Offit, MD, MPHMemorial Sloan-KetteringCancer CenterNew York, NY

Funmi I. Olopade, MB, BS,FACPUniversity of Chicago MedicalCenterMade possible by RocheChicago, IL

C. Kent Osborne, MDBaylor College of MedicineHouston, TX

Barbara A. Parker, MDMoores Cancer CenterUniversity of California, San DiegoSan Diego, CA

Electra D. Paskett, PhDThe Ohio State University The Play for P.I.N.K. AwardColumbus, OH

Edith A. Perez, MDMayo Clinic - Jacksonville, FLMade possible by RocheJacksonville, FL

Charles Perou, PhD University of North CarolinaChapel Hill, NC

Martine J. Piccart, MD, PhDBreast International GroupInstitut Jules Bordet Brussels, Belgium

Lori J. Pierce, MDUniversity of MichiganAnn Arbor, MI

Peggy L. Porter, MDFred Hutchinson CancerResearch CenterSouthwest Oncology GroupMade possible by Macy’sSeattle, WA

Michael F. Press, MD, PhDNorris Comprehensive CancerCenter University of SouthernCaliforniaLos Angeles, CA

Lajos Pusztai, MD, D. PhilUniversity of TexasMD Anderson Cancer Center Houston, TX

Andrew A. Quong, PhDGeorgetown UniversityWashington, DC

Neal Rosen, MD, PhDMemorial Sloan-KetteringCancer CenterThe Joseph and Arlene TaubFoundation AwardNew York, NY

Regina M. Santella, PhD Mailman School of PublicHealthColumbia UniversityNew York, NY

Richard L. Schilsky, MDUniversity of ChicagoCancer and Leukemia Group BChicago, IL

Robert J. Schneider, PhDNYU School of MedicineNew York, NY

Ruby T. Senie, PhDMailman School of PublicHealthColumbia UniversityNew York, NY

Vandana Sharma, MD, PhDStanford UniversityAmerican Society of ClinicalOncologyStanford, CA

Moshe Shike, MDMemorial Sloan-KetteringCancer CenterNew York, NY

George W. Sledge, MDIndiana University School ofMedicineIndianapolis, IN

Benjamin Smith, MDYale University School ofMedicineAmerican Society of ClinicalOncologyThe Hirschhorn AwardNew Haven, CT

Ian E. Smith, MD, FRCPRoyal Marsden Hospital andInstitute of Cancer ResearchMade possible by AstraZenecaLondon, UK

Lawrence J. Solin, MDUniversity of PennsylvaniaPhiladelphia, PA

Christos Sotiriou, MD, PhDInstitut Jules Bordet Brussels, Belgium

Annette L. Stanton, PhDUniversity of California, LosAngelesLos Angeles, CA

Vered Stearns, MDJohns Hopkins University Schoolof MedicineBaltimore, MD

W. Fraser Symmans, MDUniversity of TexasMD Anderson Cancer CenterHouston, TX

Antoinette R. Tan, MD,MHSc Cancer Institute of New JerseyUniversity of Medicine &Dentistry of New JerseyAmerican Society of ClinicalOncologyNew Brunswick, NJ

Mary Beth Terry, PhDMailman School of PublicHealthColumbia UniversityNew York, NY

Ilan Tsarfaty, PhDSackler School of MedicineTel Aviv UniversityTel Aviv, Israel

George F. Vande Woude, PhDVan Andel Research InstituteGrand Rapids, MI

Kala Visvanathan, MBBS,FRACP, MHSJohns Hopkins Bloomberg Schoolof Public HealthMade possible by RocheBaltimore, MD

Geoffrey M. Wahl, PhDSalk Institute for BiologicalStudiesLa Jolla, CA

Shaomeng Wang, PhDUniversity of Michigan Ann Arbor, MI

Wei Wang, MD, PhDFred Hutchinson CancerResearch CenterAmerican Society of ClinicalOncologySeattle, WA

Robert A. Weinberg, PhDWhitehead Institute forBiomedical ResearchCambridge, MA

Ralph Weissleder, MD, PhDMassachusetts General HospitalHarvard Medical SchoolBoston, MA

Michael Wigler, PhDCold Spring Harbor LaboratoryThe Play for P.I.N.K. AwardCold Spring, NY

Walter C. Willett, MD, Dr. PHHarvard School of Public HealthMade possible by RocheBoston, MA

Eric P. Winer, MDDana-Farber Cancer InstituteBoston, MA

William C. Wood, MDEmory University on behalf ofThe Breast Cancer Intergroup& Breast International Group

Richard C. Zellars, MDJohns Hopkins University School of MedicineBaltimore, MD

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Winter Newsletter 2006 11The Breast Cancer Research Foundation10

The Estée Lauder Companies Breast Cancer Awareness Campaign made October 2005 the most memorable BreastCancer Awareness month yet. Millions of pink ribbons were distributed and Aveda, Bobbi Brown, Donna Karan, EstéeLauder, Jo Malone, La Mer, Origins, Prescriptives, Stila and Tommy Hilfiger created pink products, including EstéeLauder Pure Color Crystal Gloss in Evelyn Pink. On September 14th, Evelyn Lauder, Elizabeth Hurley, spokesmodel forEstée Lauder and its Breast Cancer Awareness Campaign, Sean “Diddy” Combs and Bloomingdale’s Chairman andCEO Michael Gould, hosted “Give Breast Cancer the Pink Slip!,” a cocktail party in NYC to launch Mr. Combs’ “PinkSlip” camisole sold exclusively at select Bloomingdale’s to benefit BCRF. Continuing their awareness-boosting activities,on October 6th Evelyn Lauder and Elizabeth Hurley traveled to Saks Fifth Avenue in Boston and illuminated thePrudential Center. As always, the Estée Lauder Companies employees actively supported BCRF with their annual Sale-a-bration, on-line silent auction, Aramis bake sale, raffles, and La Mer sales as well as walks, golf, soccer and othersports outings.

14th ANNUAL ESTÉE LAUDER COMPANIES BREAST CANCER AWARENESS CAMPAIGN GIVES BREAST CANCER THE PINK SLIP

Pink Slip LoungeEvelyn Lauder announcing the kick-off of The Estée Lauder Companies’ 2005 Breast CancerAwareness Campaign and thanking Sean “Diddy” Combs for designing the fabulous pinkcamisole she is wearing. Elizabeth Hurley and Michael Gould (far right).

Prudential CenterPrudential Center in Boston turned pink in October.

Kensington PalaceThe Estée Lauder Companies illumination initiative is in its sixth year.Kensington Palace, London

events

Honoring New England Researchers After painting Boston pink, Evelyn Lauder and Elizabeth Hurley joinedDr. Larry Norton as Honorary Chairmen of the Hot Pink Dinner atThe Four Seasons. The event, co-chaired by Sandy Krakoff and KarenWebster, honored the Foundation’s fourteen New England researchers.

The Hot Pink Dinner raised over $140,000 for BCRF. An auctionprize, featuring a fabulous Red Sox package for four, donated by RedSox President Larry Lucchino and his wife Stacey, along wth baseballgloves from Nokona and a $1,000 shopping spree at Saks, was so popu-lar that it sold twice, raising a total of $16,000. In 2005, the Foundationawarded $3.2 million in grants to New England researchers.

Target Pink ContinuesTarget kicked off Breast Cancer Awareness Month in New York City with a free concert by the artist “Pink” who donated $50,000 to BCRF. Target also handed outfree coffee, doughnuts and MetroCards as part of a “Random Acts of Kindness Day.”Target definitely hit the bull’s-eye again, raising $300,000 with their second consecutive exclusive pink product collection. There were over 20 items this year,including pink polo shirts, a men’s tie, and cashmere flip-flops. A remarkable 100 percent of the net profits benefit BCRF.

Myra Biblowit accepts $50,000 check from Pink Buying Target pink products at the free “Pink” concert at the South Street Seaport, NYC

Random Acts of Kindness in NYC

Larry Schlager, Judie Schlager, Dr. Larry Norton, Jean Sharf, Fred Sharf Stacey Lucchino, Lawrence Lucchino, Karen Webster, Evelyn Lauder, Elizabeth Hurley

Jeanette Wagner, Dr. Judah Folkman, Myra Biblowit

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Photo exhibition by Evelyn LauderBeauties and other New WorkEvelyn Lauder kicked off her newest photography exhibitiontour at the Pace/MacGill Gallery in NYC in November. Theexhibition tour, made possible with generous underwriting byThe Phoenix Companies, Inc., was a resounding success, withover $73,000 raised through exhibition sales. The tour continues: Arthur Ross Gallery, University of Pennsylvania,Philadelphia, from June 15 - July 2006; the Baldwin Gallery inAspen, Colorado in summer 2006; and the John BerggruenGallery in San Francisco, California in 2006.

BCRF's Junior Host Committee heldthe “Party In Pink” in November atLoft 11 in New York City. Over 300

young professionalsshowed up to dance tomusic by DJ Vibe andraise awareness amongthe group, which willbenefit from all of thecurrent advances inbreast cancer research.Support from Cambria,Coach, Future BrandsLLC, Glamour, GoldmanSachs, and Mr. and Mrs.Randall King made theevent a success, raisingmore than $30,000.

PARTY IN PINK

On August 19th, 160 guests gathered under the tent at The Reading Room for the 3rd annual luncheon inSaratoga Springs, NY. Lunch was followed by an information discussion with Dr. Larry Norton entitled“Rapid Advances in Our Understanding and Managementof Breast Cancer.” The event raised over $114,000.

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2 0 0 5 : A Y E A R I N T H E P I N KWhat do you get when you cross a gleaming new record with the color pink? Play forP.I.N.K.’s 2005 season! As the 2006 season is launching in Florida, we are thrilled toannounce an unsurpassed number of participants, an expansion to over 100 tournaments in twelve states and a record-breaking amount of funds raised.

On November 1st, Play for P.I.N.K.’s (PFP) board proudly presented The Breast CancerResearch Foundation with a $1,700,000 check, bringing its total contributions to $8 mil-lion! All of the clubs that held their first PFP events were met with resounding success.Some examples: Colleton River Plantation, which raised over $40,000, while StantonRidge brought in almost $20,000. The inaugural “Paint the Town Pink” walk in NorthArlington, NJ contributed over $6,000. The next walk will be September 30, 2006.Contact Patty at www.pinkribbonwalk.com for information.

PFP’s contribution to BCRF funds five of the nation’s leading breast cancer researchers:Robert Benezra, PhD, Teresa Gilewski, MD, Philip O. Livingston, MD, Electra D. Paskett, PhD and Michael Wigler, PhD.

P L AY F O R P. I . N . K .

Play for P.I.N.K. at Alpine CountryClub in Alpine, NJ

Play for P.I.N.K. participants at the Shore and Country Club, East Norwalk, CT

Play for PINK at Bocaire Country Club in Boca Raton, FL The Play for P.I.N.K. board presented a $1.7 million check to Evelyn Lauder

events

Fabiola Beracasa and Patricia Sorenson

Elizabeth Valando, Carol Farmer, Debby Oxley

Junior Committee Chairman Funa Maduka

Leonard Lauder and Ingrid Sischy Bobbi Brown

Peter MacGill and Glenn Lowry Celso Gonzalez-Falla,Adam WeinbergKevin Lawler,Tisa Rabun, Cherri Divin, Evelyn Lauder, Heidi Sirota,Joleen Speight, Jack Sharry

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Visit www.playforpink.org to find out about ongoingachievements, happenings,how to get involved or to make a donation.

Upcoming Tournaments in Florida:January 13 Boca Woods Tennis, January 14 Bear’s Paw, January 19 Terravita, January 23 Bear’s Paw, January 24 The Polo Club, January 25 The Loxahatchee Club, February 2 Eastpointe; Palmira, February 6 BocaWest, February 7 Gleneagles; Aberdeen, February 9 Ballen Isles, February 9 Boca West, February 14 Turnberry Golf& Tennis; Ballen Isles, February 16 Broken Sound, February 19 Shadow Wood, February 21 Atlantis, February 22 Trump International, February 28 Boca Woods Golf, February 28 St. Andrews, March 9 Sailfish Point,March 11 Dressage Challenge, April 1 The Links at Boynton Beach, April 2 Bocaire, April 4 Delaire, April 6 CC of Naples, April 18 Sea Pines

The Breast Cancer Research Foundation14 Winter Newsletter 2006 15

Danskin Women’s Triathlon For the 2nd year, BCRF was the official charity of Danskin Women'sTriathlon Series. Over 20,000 women participated, raising over$146,000 for BCRF. The series celebrated its 100th race this year.

The first ever pink plane: During October, Song‚ Delta AirLines’ low-fare service, raised $75,000 for BCRF through on-board donations from passengers, proceeds from non-alcoholic “pink beverages” sold on-board and proceeds fromthe sale of “pink products” in local Song markets. From

January throughMarch, you candonate yourDelta SkyMilesto BCRF bylogging ontodelta.com/sky-wish. See page16 for details.

thank you

Holt Renfrew hostedthe launch of BCRF’sfirst Canadian effortincluding selling theexclusive pink cash-mere T-shirt thatElizabeth Hurley iswearing. Holt

Renfrew donated $50,000.00 (CAN) andAmerican Express donated $15.00 forevery cashmere tee purchased on anAmex Card.

What could be sweeter than a cure? Marshall Field's limited edition pink Frango®

Mints is raising more than $100,000 for BCRF. Pictured: Miranda Moss, a breastcancer survivor whocreated the Frango artwork, Elizabeth Hurley,Myra Biblowit, EvelynLauder, Frank Guzzetta,Dr. Funmi Olopade.

Fauchon’s Octoberwindows on Park Ave.

in NYC

Carmen Marc Valvo donated $10,000 from the trunkshow at Bergdorf Goodman, NYC. Pictured: CarmenMarc Valvo, Deborah Krulewitch, Jeanette Wagner.

Barbara Zinn Moore hands Myra Biblowit acheck for $25,000 from Lord & Taylor’s

Mother’sDay 2005promotion.

The international hit show MAMMAMIA! has been supporting BCRF foryears by selling the Rock ChickSupremo T-shirt throughout theworld. To date the sales have generated over $300,000.

people helping people

1: Rich Lehrer, Dan Brestle,William Lauder, Roger Caracappa at the Estée Lauder Third Annual "Play for Pink" Long Island Golf Classic. Through the generosity and support of many, this year turned out to be the most successful yet, raising over $74,000. 2: “Call Me Larry” from Find a Cure Stable is named for Dr. Larry Norton.This horse, owned by Suzie and Doc O’Cain, will be running for BCRF. 3: Beth Carr, Erin McGraw and Elizabeth White of Georgetown Visitation Preparatory School inWashington, DC raised money by creating and selling "exam goodie bags" to parents before exam week. This is one example of the “Think Pink” club’s efforts. The students donated $10,000, doubling previous years. 4: On October 5th, the Estée Lauder Northeast Sales Team held its fifth annual walk to benefit BCRF. The 80member Sales Team made their way along Boston’s historic waterfront and raised over $22,000. 5: Lehigh Valley Miata Owners Club’s first Drive to Survive tourtopped $8,000 and they only had half the cars they wanted. Pictured: Louis DePaul, Pat Rizzotto, Rich Young, Bob Young, Jean Rymon, Brent Rymon, Sharon DePaul.6: For the 3rd year, Debbie Adelman-Snyder arranged a “Pink Ribbon Walk” in Holmdel, NJ, and hosted a party in NYC in celebration of two years of her continued goodhealth. Debbie has raised over $40,000 for BCRF.

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BCRF salutes all individuals and companies large andsmall, who commit timeless hours to generate moneyfor research. There are many people to thank - every-one who bought a pink product, or a Love Cures card,the brave men and women of our Survivor CirclePartnership program, friends at Wilson, D'ArrigoBrothers, Boscov's, Bon-Ton, Fortunoff', Prides CornerFarms, Ouidad, Burberry, For Eyes, Coach, Ann Taylor,Aveda and Carolee, the Dashing Divas, all the Buncofor Breast Cancer players, quilters from Quilters AtSea. Many are included in this newsletter, yet the listgoes on and on. Every dollar is one dollar closer to acure. Here are snapshots of various efforts.

NON-PROFIT ORG.

US POSTAGE PAID

NEW YORK, NY

PERMIT NO. 2405

The Breast Cancer Research Foundation60 East 56th Street, 8th FloorNew York, New York 10022

ADDRESS SERVICE REQUESTED

ResearchFoundation TM

BreastCancer

The

SkyMiles MembersDonate your Delta miles to BCRF

BCRF has been named Delta's Charity of FirstQuarter 2006.There is a 5,000-mile minimum andDelta will add one mile for every 5 miles youdonate. Information can be found atdelta.com/skywish. Every mile helps.

BCRF Contact Info:Phone: 646.497.2600Toll-Free: 866.FIND.A.CUREemail: bcrf@bcrfcure.orgwww.bcrfcure.org

your pink calendar...

February 13thThe Hot Pink Symposium and Luncheon,Flagler Museum, Palm Beach, FL

February 14thEvelyn Lauder keynote speaker at theJewish Federation of Dallas Women'sLuncheon, Dallas, TX

February 26thPolo and Think Pink” Luncheon, Windsor, Vero Beach, FL

March 11thInternational Quadrille TeamChallenge, Wellington, FL

March 13th9th Annual HousewaresCharity Foundation Dinner,Sheraton Hotel, Chicago, IL

April 10thThe Very Hot Pink Party, The Waldorf=Astoria, NYCThis year Sir Elton John is bringingTony Bennett.

PresidentMyra Biblowitmyrabib@bcrfcure.org646.497.2601

Deputy Director Margaret Mastriannipegmast@bcrfcure.org646.497.2604

Bibi AliReceptionistbali@bcrfcure.org646.497.2600

Patricia AltmanSenior Manager, PSA andInternetpaltman@bcrfcure.org646.497.2603

Marci BrenholzAssistant Manager,Development Activitiesmbrenhol@bcrfcure.org646.497.2612

Mary BriggsExecutive Assistant/OfficeManagermbriggs@bcrfcure.org646.497.2613

Anna DeLucaConsultant for Public Relationsannadeluca@aol.com646.497.2609

Carol EdwardsDatabase Administratorcedwards@bcrfcure.org646.497.2607

Robbie FinkeDirector, Marketing andCorporate Sponsorships rfinke@bcrfcure.org646.497.2614

Stephanie HamburgerDirector, Play for P.I.N.K.Assistant Director,Special Eventsshamburg@bcrfcure.org646.497.2605

Kathleen HirdtAssociate, Special Eventskhirdt@bcrfcure.org646.497.2606

Anne MacGillivrayDirector, Special Eventsamacgill@bcrfcure.org646.497.2602

Kara OppenheimAssociate, Marketingkoppenhe@bcrfcure.org646.497.2616

Jamie RiceCoordinator, Special Eventsjamrice@bcrfcure.org646.497.2622

Claire SpoorsInterncspoors@bcrfcure.org646.497.2608

BCRF STAFF