CatalunyaBioNanoMed

The Catalan nanobiomedicine

alliance

CatalunyaBioNanoMed

The Catalan nanobiomedicine

alliance

Nanobiomedicine is one of the strong points of research in Catalonia (Biocat Report 2009*). Catalonia is the pioneer in Spain and has created specialised centres which are now international references in this area. According to publications by the United States National Library of Medicine (PubMed) a member of the NIH (National Institute of Health), Barcelona is the second city in the world, after Boston, for the origin of scientific publications on nanomedicine. Catalonia – one of the most outstanding bioregions in Southern Europe - has a growing number of biotechnology and chemical-pharmaceutical companies doing research on, or using, nanotechnology in their processes. Proof of this is the information contained in this brochure, a collection of research groups, institutions and companies whose priority area is research into nanobiomedicine.

On the basis of this potential, the BioNanoMed Catalonia alliance has been created to favour synergy between groups, centres, hospitals and companies carrying out research in nanotechnology applied to health and biotechnology in Catalonia, enabling them to create new business and research opportunities, and to further increase the international footprint of this platform.

* www.biocat.cat/en/publications/report

Activity Technology

AROMICS

BIOKIT

BIO/NON-BIO INTERACTIONS FOR REGENERATIVE MEDICINE GROUP (IBEC)

CELLULAR BIOMECHANICS GROUP (IBEC)

NANOBIOENGINEERING GROUP (IBEC)

NANOPROBES AND NANOSWITCHES GROUP (IBEC)

CENTRE D’INVESTIGACIONS EN BIOQUIMICA I BIOLOGIA MOLECULAR PER NANOMEDICINA

ENDOR NANOTECHNOLOGIES SL

GP PHARM / LIPOTEC

HEREDITARY CANCER GROUP

MOLECULAR NANOSCIENCE AND ORGANIC MATERIALS

NANOBIOELECTRONICS & BIOSENSORS GROUP

NANOBIOSENSORS AND BIOANALYTICAL APPLICATIONS GROUP

NANOBIOTECHNOLOGY AND BIOMOLECULAR DIAGNOSTICS GROUP

HOSPITAL CLÍNIC DE BARCELONA

LEITAT

CELLULAR BIOMECHANICS GROUPDaniel NavajasStudy of the mechanical properties of the airway and lung tissues and the changes that occur in the context of the mechanical dysfunction associated with respiratory diseases. Development and application of cutting edge nanotechnology and advanced biophysical techniques to probe the mechanical behavior of the cells and their mechanical interactions with the microenvironment.

BiotechnologyHuman health- Imaging diagnostic

BiophysicsNanotechnology

NANOBIOENGINEERING GROUPJosep SamitierConverging and assembling micro-nano-bio systems to develop exciting nanomedicine applications.The expertise on biosensors and integration is combined to yield lab-on-a-chip solutions for point-of-care diagnostics. The group also works to provide tools for the functionalization of biomaterials at the nanoscale, providing physical and chemical cues to control cell development.

Human health- In vitro diagnosis

BiomaterialsNanotechnology

NANOPROBES AND NANOSWITCHES GROUP Pau Gorostiza | Fausto Sanz

Developing Nano scale tools to study biological systems. These tools include instrumentation based on proximity probes, like Electrochemical Tunneling Microscopy and Spectroscopy that we are applying to study metal oxides and redox proteins.

BiotechnologyHuman health- Imaging diagnostic

NanotechnologyOptics / photonics

ENDOR NANOTECHNOLOGIES SLwww.endornanotech.com - Marc Ramis | marc.ramis@endornanotech.com

EDS lead program for therapeutics is an innovative delivery system for agents with great potential to be applied in oncology. EDS is an advanced delivery system for therapeutic agents both small molecules and biologicals (organic drugs, siRNA, proteins or monoclonal antibodies).

Human health- Pharmacological or biological therapeutics

- Medical devices- In vitro diagnosis

NanotechnologyMedicinal chemistry

BIOKITwww.biokit.com - Pau Brugera | pbruguera@biokit.com Biokit is an in-vitro diagnostics company which develops innovative, high quality proprietary and OEM immunoassays for infectious serology, clinical chemistry, immunochemistry and coagulation testing. The company specializes in antigen and antibody production and purification, ELISA, latex agglutination and chemiluminescence.

Biotechnology Human health

BiomaterialsOther

AROMICSwww.aromics.es - Carme Plasencia | carme.plasencia@aromics.es

Applied Research using Omic Sciences (AROMICS) is a Barcelona-based biotechnology company that specializes in functional genomics and proteomics technologies and their application in research and development of novel therapies and diagnostic products targeting relevant human health diseases. As a company, we are focused on three major therapeutic areas: oncology, infectious diseases and neurodegenerative diseases.

Nanotechnology

ADVANCELLwww.advancell.net - Clara Campas / Ana VilaBiotechnology company with its own technology and continuous innovation; it deals with unresolved questions in health and wellbeing using value-added efficient products and services. The company thrives on its discoveries from the academic environment and improving, developing and licensing them to third parties or launching them on the market.

INSTITUTE FOR BIOENGINEERING OF CATALONIA (IBEC)www.ibecbarcelona.eu | info@ibecbarcelona.eu

A cross-disciplinary approach to deliver smart, third generation biomaterials for tissue engineering and regenerative medicine. Engineering advanced polymer surfaces with nanoscale tools and techniques for their functionalization and characterization.

Biotechnology Human health - Medical devices

BIO/NON-BIO INTERACTIONS FOR REGENERATIVE MEDICINE GROUPJosep A. Planell

Others: Bioengineering and nanomedicine

Biophysics Biomaterials Cristalography

Nanotechnology Peptides & proteins

CENTRE D’INVESTIGACIONS EN BIOQUÍMICA I BIOLOGIA MOLECULAR PER NANOMEDICINA (CIBBIM-NANOMEDICINA) VALL D’HEBRON INSTITUT DE RECERCA- VHIRwww.cibbim.eu - Simó Schwartz Jr | sschwartz@ir.vhebron.net

Our projects and current patents (13) are focused into the identification of new disease biomarkers and therapeutic targets, and the development of new drug delivery and targeting approaches for clinical applications in oncology and rare diseases.

BiotechnologyHuman health- Pharmacological or biological therapeutics

- In vitro diagnosis- Imaging diagnosticOthers: pre-clinic studies

In silico analysisBiostatisticsBioinformaticsBiomaterialsGenomics

NanotechnologyPeptides & proteinsProteomicsOthers

NANOBIOSENSORS AND BIOANALYTICAL APPLICATIONS GROUPCIN2-CSIC; CIBER-BBNwww.ci2.es/biosensores - Laura M. Lechuga | laura.lechuga@cin2.es

Technological development of nanophotonic (plasmonics and silicon-based) and nanomechanical biosensors based on proper technology, integration in point-of-care platforms and their application in real clinical diagnostics. Two spin-offs have been launched.

BiotechnologyEnvironment

Human health- In vitro diagnosis

NanotechnologyOptics / photonics

LEITATwww.leitat.org - Francesc Mitjans | fmitjans@leitat.orgMonoclonal antibodies , cellular models, in vivo models, ADME, cellular safety models. Ongoing FP7 European Projects: NANOPOLYTOX, NANOTHER, and NANOTEST. Ongoing National Projects: VACMON, NANOMOLECULAR, ROBOCELL, and ROBIOCAT.

BiotechnologyEnvironmentFood & nutritionHuman health

- Pharmacological or biological therapeutics- Medical devices- In vitro diagnosis- Imaging diagnosis

BiomaterialsBioprocessesBioremediationNanotechnologyPeptides & proteins

HOSPITAL CLÍNIC DE BARCELONAwww.hospitalclinic.org - Joan Bigorra | bigorra@clinic.ub.es

Translational Research in Cancer, GI and Liver Diseases, Cardiovascular, Pulmonary Diseases, Neurosciences, Diabetes, Metabolic Diseases, Infectious Diseases. NOTES Surgery, Medical Imaging, Telemedicine, Health System Research.

BioinformaticsBiotechnologyHuman health

- Pharmacological or biological therapeutics- Medical devices

- In vitro diagnosis- Imaging diagnosis- E-health / electro medicine

NANOBIOELECTRONICS & BIOSENSORS GROUPINSTITUT CATALÀ DE NANOTECNOLOGIA www.icn.cat/nanobioele-ctronics-biosensors.php - Arben Merkoçi | arben.merkoci.icn@uab.es

Development of low cost and efficient nanomaterials based sensors and biosensors including lab-on-a-chip for diagnostics, environmental monitoring, safety and security between other industrial applications.

BiotechnologyEnvironmentHuman health- In vitro diagnosis

Animal health- Pharmacological or biological therapeutics

BiomaterialsBioprocessesNanotechnologyPeptides & proteins

NANOBIOTECHNOLOGY AND BIOMOLECULAR DIAGNOSTICS GROUPINSTITUT DE QUÍMICA AVANÇADA DE CATALUNYA-CSICwww.iqac.csic.es/amrg - Pilar Marco | pilar.marco@cid.csic.es

New approaches and strategies for improved diagnostic methods and devices based on the combination of micro/nanotechnological and biotechnological advances to create functional (bio)hybrid materials, in which optical or electrical signals can be recorded as a consequence of specific biorecognition events. Development of antibodies with tailored properties.

BiotechnologyFood & nutritionHuman health- Medical devices

- In vitro diagnosisAnimal health- In vitro diagnosisOthers: Nutrition

BiomaterialsBioprocessesNanotechnologyPeptides & proteins

IDIBELLwww.idibell.cat - Emilià Pola / Montse BallarinBellvitge Biomedical Research Institute (IDIBELL) is a research centre focused on cellular medicine, where the high level basic research focuses and works on relevant clinical matters and the economic development. The centre manages the research of the Bellvitge University Hospital, the Institut Català d’Oncologia (Catalan Institute of Oncology), the University of Barcelona and the Institute of Image Diagnosis.

GP PHARM / LIPOTECwww.gp-pharm.com - Alberto Bueno

GP Pharm, is a Spanish biopharmaceutical company of the Lipotec Group. The company is focused on research, development, manufacturing and marketing of products for injection within Urology and Oncology fields, based in proprietary Drug Delivery Systems. These technological platforms include micronanospheres and liposomes.

Human health

HEREDITARY CANCER GROUP ICO-IDIBELL-IMPPCGabriel Capella - gcapella@idibell.catMolecular characterization of alleles of moderate risk predisposing to colorectal cancer: I1307K as a model system. Search of new genes predisposing to familial breast and colorectal cancer. Risk quantification in neurofibromatosis. Psychological impact of genetic counseling.

BiotechnologyHuman health- Pharmacological

or biological therapeutics- In vitro diagnosis

In silico analysisBiostatisticsBioinformatics

GenomicsProteomics

MOLECULAR NANOSCIENCE AND ORGANIC MATERIALS NANOMOL www.icmab.es/nanomol - www.icmab.es/nmmo - Jaume Veciana | vecianaj@icmab.es

Fine chemistryFood & nutritionHuman health:- Pharmacological or

biological therapeutics- E-health / electromedicineAnimal health:- Pharmacological or

biological therapeutics- Medical devices- E-health / electromedicine

BiophysicsBiomaterialsNanotechnologyMedicinal chemistry

CatalunyaBioNanoMed

Institute for bioengineeringof Catalonia

Edited by:

info@bionanomedcat.org - www.bionanomedcat.org