the clinical translational science ontology affinity group

7/28/2019 The Clinical Translational Science Ontology Affinity Group

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The Clinical and Translational

Science Ontology Affinity Group

William R. Hogan, MD, MS

March 19, 2013

AMIA Translational BioinformaticsSummit

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What is it?

Technically speaking, an affinity group of the

Informatics Key Function Committee of the

CTSA Consortium

A group of people interested in pursuing

answers to the question how can ontologies

best enable translational science?

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ONE NEED NOT BE A CTSA CONSORTIUMMEMBER TO PARTICIPATE


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October 2010

Hogan and Scheuermann hatch idea at dinner duringIKFC meeting

Spring 2011Initial proposal takes shape, distributed to folks forfeedback

Winter (of discontent) 2011-2012

Proposal submitted to Operations Committee of IKFCand returned with questions and request for revisionsand clarification

History


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April 2012 First Clinical and Translational Science Ontology

Workshop held in Baltimore, MD

Participants enthusiastic about forming ontology-related AG in IKFC

Given takeover of CTSA Consortium support by C4,old AG proposal forms no longer in use

Proposal split into elevator pitch and operations

documents July 2012

Elevator pitch and operations documents submitted toIKFC Operations Committee

History (continued)


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November 2012

C4 and IKFC Operations Committee member inform

Hogan that the Clinical and Translational Science

Ontology Affinity Group (CTSO-AG) is approved!

December 2012

C4 sets up infrastructure for CTSO-AG on

ctsacentral.org

CTSO-AG keeps Google Group for inclusion of

members outside Consortium

History (continued)


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January 2013

First CTSO-AG monthly call held

February 2013

Second Clinical and Translational Science OntologyWorkshop held in Orlando, Florida (sponsored byTranslational Research Institute of UAMS and co-sponsored by NCBO)

March 2013

Second CTSO-AG call held

History (continued)


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Defining subject matter of the AG

Ontology in support of CTSA evaluation

Identifying and cataloging projects, software,research studies, etc. that use ontologies and theontologies they employ

Generating a tutorial on ontology targeted atjunior translational science investigators

Current Activities


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Are we interested in any type of controlled

vocabulary, thesaurus, taxonomy,

classification, etc.?

If not, what are the distinctions and why do

they matter?

White paper is currently on v6 and very close

to distribution to entire CTSO-AG

Lead: Mathias Brochhausen

Definition Activity


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Collaboration with evaluation KFC

Representing key metrics for interoperability ofevaluation data

Has links to CTSAConnect project to deliverinvestigator data (e.g., grants, pubs) data into theprocess

Two-page proposal distributed for feedback, with

ultimate goal of obtaining buy in from leadershipof Evaluation KFC

Lead: Dagobert Soergel

Evaluation Activity


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If we are going to understand how ontologies

enable translational science, then we need to

track their use and associated outcomes

Setting up Wiki site

Made initial decisions for organization of site

Lead: William Hogan

Catalog Activity


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Initial goal is deck of ~60 PowerPoint slides

Currently collecting folks existing tutorials,slides, videos, Wikis, etc.

Leads: He, Brochhausen, Soergel, Hogan

Tutorial Activity


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Google grouphttp://groups.google.com/group/ctsa-ontology

[email protected]

C4 sitehttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-ag

[email protected]

CTSO Workshops

First:http://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshop

Second:http://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshop

Where to Find Stuff
http://groups.google.com/group/ctsa-ontologymailto:[email protected]://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-agmailto:[email protected]://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://ncorwiki.buffalo.edu/index.php/CTSA_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshophttp://www.bioontology.org/wiki/index.php/Clinical_and_Translational_Science_Ontology_Workshopmailto:[email protected]://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-aghttps://ctsacentral.org/committee/ikfc-clinical-and-translational-science-affinity-group-ctso-agmailto:[email protected]:[email protected]:[email protected]://groups.google.com/group/ctsa-ontologyhttp://groups.google.com/group/ctsa-ontologyhttp://groups.google.com/group/ctsa-ontology


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Elevator pitch and operations documents

https://groups.google.com/forum/?fromgroups=#!t

opic/ctsa-ontology/BysA64zEKzc

Dropbox for tutorial effort (send request to

join to Hogan)

Where to Find (continued)
https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=https://groups.google.com/forum/?fromgroups=


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Email [email protected] with: The email address you want to subscribe

Whether you are with member institution of CTSAConsortium and signed up to IKFC

Whether email address above is the one subscribed toIKFC

Join monthly calls (details emailed to both GoogleGroup and C4 listservs) Second Tuesday of the month at 2p ET

Next one is Tuesday, April 9 at 2p ET

Engage one of the current activities and drive itforward!

How to Participate in CTSO-AG
mailto:[email protected]:[email protected]


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Those instrumental to formation of group:Richard Scheuermann Barry Smith

Warren Kibbe Lindsay Cowell

Melissa Haendel Jesse Tennenbaum

Mathias Brochhausen Dagobert Soergel

JENNIFER BUFFORD!

And the remainder of the 37 participants of the firstWorkshop who self-identified as being interested inparticipating

IKFC Operations Committee for their valuablecriticisms, suggestions, recommendations, etc.

Award UL1TR000039 from NCATS

Acknowledgements

the clinical translational science ontology affinity group

Documents