the effect of a “one for the road” drink of hard liquor ... · the effect of a “one for the...

6
The effect of a “one for the road” drink of hard liquor, beer or wine on peak breath alcohol concentration in a social drinking environment with food consumption Martin H. Breen, M.S., Qui T. Dang, M.S., Joseph T. Jaing, B.S., Greta N. Boyd, Orange County Sheriff-Coroner’s Department, California Forensic Science Services INTRODUCTION Even though it is a traffic violation to drive a motor vehicle with a blood alcohol concentration (BAC) of 0.08% or higher; there are over 20,000 individuals who are arrested every year for this violation in Orange County, California. The majority of these drivers consume different types of alcoholic beverages including hard liquor, beer, and wine from a bar or a party over a period of a few hours and with dinner or a snack. Expert witnesses testifying in driving under the influence of alcohol cases are often asked in court to back-extrapolate the driver’s BAC at the time of the traffic stop by using the known result of a blood, breath or urine test administered one or two hours after the incident. Since BAC is a function of time, the driver’s BAC at the time of driving could be lower than the BAC at the time of the chemical test. This rising BAC (Jones, 1990) is often seen in drivers who have a “one for the road” drink just before they are pulled over by a police officer on the suspicion of driving under the influence of alcohol. In order to properly calculate the driver’s BAC at the time of driving (M.J. Lewis, 1986; K.O. Lewis 1987; Dubowski, 1985; Jones, 1988), detailed information such as the driver’s drinking pattern, the type of alcoholic beverage consumed, and the presence or absence of food in the driver’s stomach (Jones, 1991; Holt, 1981; Rose, 1979; Wilkinson, 1977) must be taken into consideration. Although there are studies reporting that the majority of alcohol is absorbed quickly (Gullberg, 1982) even when it is consumed together with a large meal (Jones and Neri, 1991), no previous study has reported the absorption and distribution of the “one for the road” drink. The purpose of this series of studies is to examine the maximum increase in breath alcohol concentration and the time it takes to reach the peak after finishing the “one for the road” drink. The same individuals consumed hard liquor, beer or wine on three separate occasions in a social - 739 -

Upload: dinhcong

Post on 22-Oct-2018

214 views

Category:

Documents


0 download

TRANSCRIPT

The effect of a “one for the road” drink of hard liquor, beer or wine on peak breath alcohol concentration in a social drinking environment with food consumption

M a rtin H . B r e e n , M .S ., Q u i T . D a n g , M .S ., J o se p h T . J a in g , B .S .,

G reta N . B o y d ,

O range C ounty Sheriff-C oroner’s D epartm ent, C alifornia

F orensic Science Services

IN T R O D U C T IO N

E ven though it is a traffic violation to drive a m otor vehicle w ith a b lood alcohol concentration

(BAC) o f 0 .08% o r higher; there are over 20 ,000 individuals w ho are arrested every year fo r

this violation in O range C ounty , C alifornia . T he m ajority o f these d rivers consum e different

types o f alcoholic beverages including hard liquor, beer, and w ine from a bar o r a party over a

period o f a few hours and w ith d inner o r a snack.

Expert w itnesses testify ing in driving under the influence o f alcohol cases are often asked in

court to back-extrapolate the d riv er’s B A C at the time o f the traffic stop by using the know n

result o f a blood, breath o r urine test adm inistered one o r tw o hours after the incident. Since

B A C is a function o f tim e, the d river’s B A C at the tim e o f driv ing could be low er than the BAC

at the time o f the chem ical test. This rising B A C (Jones, 1990) is often seen in drivers w ho

have a “one fo r the road” d rink ju s t before they are pulled over by a police officer on the

suspicion o f driv ing under the influence o f alcohol. In o rder to p roperly calculate the d riv er’s

B A C at the time o f driv ing (M .J. L ew is, 1986; K .O . L ew is 1987; D ubow ski, 1985; Jo n e s,

1988), detailed inform ation such as the d riv er’s d rinking pattern , the type o f alcoholic beverage

consum ed , and the presence o r absence o f food in the d riv er’s stom ach (Jones, 1991; H olt,

1981; R ose, 1979; W ilk inson , 1977) m ust be taken into consideration . A lthough there are

studies reporting that the m ajority o f alcohol is absorbed quickly (G ullberg, 1982) even w hen it

is consum ed together w ith a large m eal (Jones and N eri, 1991), no p rev ious study has reported

the absorption and distribution o f the “one fo r the road” drink.

The purpose o f this series o f studies is to exam ine the m axim um increase in breath alcohol

concentration and the tim e it takes to reach the peak after finishing the “one fo r the road” d rink .

T he sam e indiv iduals consum ed hard liquor, beer o r w ine on three separate occasions in a social

- 7 3 9 -

environment with food.

M E T H O D

S u b je c ts an d c o n d itio n s

Thirteen healthy volunteers, seven m en and six w om en, participated in these studies and were

designated as subjects A through M . T hey described them selves as social d rinkers w ho

consum e alcohol only occasionally . The mean age o f the m ale and fem ale participants w as 32

and 28 years old respectively. The m ean body w eight o f the m ale and fem ale participants w as

164 and 134 pounds respectively. The subjects consum ed hard liquor fo r the first study , beer

fo r the second study and w ine fo r the third study. N ine o f thirteen subjects participated in all

three studies, w hile the rem aining subjects w ere able to participate in at least one o r m ore o f the

studies. A t the beginning o f each study, the d rinking subjects w ere requ ired to perform a breath

test show ing that they w ere alcohol free.

All subjects ate d inners w hich included com m on food such as ho t dogs, ham burgers,

sandw iches, burritos, m eatballs, rice, pasta, soup, salad, fruits and/or vegetables, immediately

before o r shortly before drinking started. Snacks w ere available throughout the study. The

subjects w ere instructed to keep the same activities fo r Day 1 and D ay 2 o f each study. A t the

com pletion o f the study, the subjects w ere driven hom e by designated drivers.

F o r each study, m onitors w ere assigned to each subject to record relevant inform ation such as

the subjects’ activities during that day, the kind o f food they had fo r d inner, the time they had

dinner, their age, sex and w eight. The m onitors also recorded the am ount o f d rinks consum ed ,

the tim e it took to consum e the d rinks, the time o f the breath tests and the duplicate breath test

results. E ach subject was assigned to the sam e breath alcohol instrum ent in D ay 1 and D ay 2 o f

each study.

E ach study consisted o f tw o consecutive days. D ay 1 served as a control in w hich the subjects

consum ed a know n am ount o f alcohol at their ow n rate until their B rA C w as near the 0 .08%

level. C hips, d ip , and o ther snacks w ere available; and the subjects talked, played cards, poo l,

etc... w ith m usic in the background. T he atm osphere w as sim ilar to that o f a bar o r a party . The

subjects’ duplicate breath sam ples w ere taken fifteen m inute after finishing each drink. A fter the

last drink, the sub jects’ B rA C s w ere m easured at 15-20 m inute intervals fo r approxim ately four

hours to establish their tim e to peak and their elim ination rates during the post-absorptive phase.

D ay 2 w as a repeat o f D ay 1 w ith the addition o f the “one fo r the road” d rink .. The subjects

w ere given a “one fo r the road” d rink w hen their B rA C started to decline. T he am ount o f

alcohol for this drink was 30 to 60 m illiliters o f hard liquor fo r the first study , 355 m illiliters o f

-7 4 0 -

beer fo r the second study and 177 m illiliters o f w ine fo r the third study. The sub jec ts’ B rA C s

w ere also recorded every 15-20 m inutes after the final drink until the com pletion o f the study ,

approxim ately tw o hours later.

The m ain purpose o f D ay 1 w as to obtain a baseline curve fo r each subject that could later be

com pared w ith the B rA C curve o f D ay 2. It was to ascertain that the B rA C increase o f the “one

fo r the road” drink in D ay 2 w as attributed to this drink and w as not affected by o ther biological

factors. It also helped to determ ine the dosage, the consum ption rate fo r each subject in D ay 2;

and to determ ine w hether o r no t a subject could handle an alcoholic beverage o ther than his/her

preference, so he/she could continue to D ay 2.

In s tr u m e n ta tio n

In toxilyzer 5000 instrum ents, m anufactured by CM I Inc., w ere used to m easure the sub jec ts’

B rA C . These instrum ents have been in use in all O range C ounty law enforcem ent agencies

since 1987. B reath tests w ere taken in duplicate and the results m ust agree within 0 .020% . If

the tw o resu lts did no t agree, a th ird test w as taken. C alibration checks w ere perform ed on each

instrum ent before, during and after its use each evening. They w ere w ithin 0 .010% o f the

know n values o f the sim ulator solution. A ir b lanks betw een sam ples gave a read ing o f 0 .000% .

A lc o h o lic b e v e r a g e s

F or hard liquor, subjects consum ed S m irnoff V odka , R onrico R um , tequila, o r W illiam s

B ourbon W hiskey . F o r beer, they consum ed M iller G enuine D raft , C orona or B ud w eise r .

F o r w ine, they consum ed M ondavi R iesling , B eringer W hite Z infandel , M ondavi Fumetf

B lanc , R u therford C abernet , C olum bia C rest M erlo t , o r chardonnay.

C a lc u la t io n s

BrA Cs w ere plotted against time to obtain the B rA C curve fo r each subject. Each data point

represents the average o f the duplicate BrACs.

D ata collected from D ay 1 o f each study w ere used to calculate the tim e to peak after the last

drink and the elim ination rate o f each subject.

D ata collected from D ay 2 in each study w ere used to calculate the time to peak and the BrA C

change after fin ish ing the “one fo r the road” drink.

Because o f a 15 m inute w aiting period for the dissipation o f m outh alcohol, the change in BrA C

after the last drink is the difference betw een the highest B rA C and the last m easurem ent before

-741 -

the last drink. Plateaus w ere observed fo r subjects w hose B rA C s rem ained w ithin 0 .010% o f

the highest B rA C ov er time w ith the beginning o f the plateau being the first data poin t w ithin

0 .010% from the h ighest m easurem ent.

R E S U L T S

S h a p es o f B rA C cu rves:

The shape o f the B rA C -tim e profile fo r m ost individuals follow ed the expected course o f a rapid

rise during absorp tion , a clear peak, and a steady fall during elim ination. A typical profile is

observed in F igure 1. The second peak representing the B rA C rise after fin ish ing the “one fo r

the road” drink is also seen in this figure. P lateau , w hich is the part o f the B rA C curve within

0.010% from the highest poin t w ithout a steady decline in B rA C over tim e is also observed and

seem s to occur m ore o ften w ith hard liquor o r w ine and is not seen in beer drinkers.

B rA C rise an d tim e to peak a fter fin ish in g th e “on e for th e r o a d ” drink:

Eleven subjects w ho had 30 to 60 m illiliters o f hard liquor gave an average B rA C rise o f

0 .017% from the last m easurem ent w ith a range o f 0.005 to 0 .034% . T he average time to peak

or plateau after this “one fo r the road” drink w as 18 m inutes w ith a range o f 0 to 35 m inutes.

T he average rise o f B rA C from 9 subjects w ho drank 355 m illiliters o f beer w as 0 .016% from

the last m easurem ent w ith a range o f 0.008 to 0.028% . The average tim e to peak or p lateau after

this “one fo r the road” beer d rink w as 16 m inutes w ith a range o f 15 to 20 m inutes. T his is

com parable to an average rise o f 0 .016% (range o f 0 .007 to 0 .026% ) from the last

m easurem ent in a 20 m inute average tim e (range o f 15 to 45 m in.) to peak again fo r 10 subjects

w ho had 177 m illiliters o f w ine “for the road.”

T im e to peak or p lateau a fter f in ish in g th e last drink:

T im e to peak or to the first point o f the plateau o f the last drink (not the “one fo r the ro ad ”) does

not d iffer significantly fo r hard liquor, beer o r w ine. The average tim e is 15 m inutes fo r hard

liquor, 19 to 22 m inutes for beer and 23 to 24 minutes- fo r w ine. The time to peak is

reproducib le w ithin 5 m inutes fo r 9 o f 11 hard liquor drinkers, fo r 5 o f 10 beer drinkers and fo r

4 o f 10 w ine drinkers. T he range o f time to peak o r plateau fo r the last d rink in this study is

from 0 to 35 min. fo r hard liquor, 15 to 40 m in. fo r beer and 5 to 60 m in . fo r w ine.

The tim e to peak o r plateau o f the “one for the ro ad ” drink is very close to that o f the last

drink.

B rA C ch a n g e a fter fin ish in g th e last drink:

The average B rA C rise from the m easurem ent before the last d rink to the peak or p lateau is from

0 .022% to 0.028% for all three types o f alcoholic beverages. T hese values are h igher than those

o f the “one for the road” d rink (0.016% to 0.017% ) because the last d rink w as consum ed while

-7 4 2 -

subjects w ere still in the absorptive phase o f the B rA C curve and the “one fo r the road” drink

w as consum ed in the elim ination phase.

F ig u re 1 : T y p ica l B rA C cu rv e o f “o n e for th e roa d ” stu d y (su b je ct A , w in e).

Time (min)

D otted lines (day 1), last d rink at 70 min.

S olid lines (day 2), last d rink at 85 m in ., “one fo r the road” d rink at 180 m in

R E F E R E N C E S

D ubow sk i, K M . (1985) A bsorp tion , d istribution and elim ination o f alcohol: h ighw ay safety

aspects. J. Stud. A lcohol Suppl 10, 9 8 -1 0 8 .

G ullberg , R .G . (1982) Variation in b lood alcohol concentration fo llow ing the last d rink . J.

Police Sci. Adm . 10(3), 2 89-96 .

H o lt, S. (1981) O bservation on the relation betw een alcohol absorption and the rate o f gastric

em pty ing . Can. M ed. Assoc. J. 124(3), 267-77.

Jones, A .W . (1988) P rob lem s and p itfa lls w ith backtracking B A C to the tim e o f driv ing . DW I

J. Law and Sci. (3), 1-4.

Jones, A .W . (M ay /Ju n e l9 9 0 ) Status o f alcohol absorption am ong drink ing drivers. J. Anal.

- 7 4 3 -

Toxicol. 14.

Jones, A .W .,Jonson , K .A ., N eri, A. (1991) P eak blood ethanol concentration and the time o f

its occurrence after rapid d rink ing on an em pty stom ach. J. Forensi. Sci. 36 (2), 376-385.

Jones, A .W .and N eri, R. (1991) Evaluation o f b lood ethanol profiles after consum ption o f

alcohol together w ith a large m eal. Can. J. Forensic Sci. 24 (3), 165-173.

Lew is, K .O . (1987) B ack calculation o f blood alcohol concentration. Br. M ed. J. 2 9 5 , 800-

801.

L ew is, M .J. (1986) B lood alcohol: The concentration-tim e curve and retrospective estim ation

o f level. J. Forensic Sci. Soc. 26, 95 -113 .

R einhardt, G . and Z ink, P. (1985) The course o f the b lood alcohol curve during and after

consum ption o f alcohol in large quantities. Long term studies in hum an vo lun teers. Biom ed.

and Social Aspects o f Alcohol, A m sterdam : E lsevier, pp 623-628.

Rose, E .F. (1979) F acto rs In fluencing gastric em ptying. J. Forensic Sci. 24 , 200-206 .

W ilkinson, P .K .,S ed m an , J.A ., S akm ar, E ., L in , Y .J .and W agner, J .G . (1977) F asting and

non fasting blood ethanol concentration follow ing repeated oral adm inistration o f ethanol to one

adult m ale subject. J. Pharmacokinet. Biopharm. 5, 41-52.

- 7 4 4 -