the effect of the ‘be clear on cancer’ campaign on stage at presentation of colorectal cancer

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Rachel Rowlands 17 th May 2013

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The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer. Rachel Rowlands 17 th May 2013. What will be covered. 2012 Be Clear on Cancer campaign Aims of the study Methodology Results Conclusions Limitations Recommendations. - PowerPoint PPT Presentation

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Page 1: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Rachel Rowlands17th May 2013

Page 2: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

2012 Be Clear on Cancer campaign

Aims of the study Methodology Results Conclusions Limitations Recommendations

Page 3: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

The DoH aims that by 2014/15 an additional 5000 lives are saved/annum due to cancer care improvements

6/52 national Be Clear on Cancer campaign launched Jan 2012:◦ Raise public awareness of two red flag symptoms

Bloody stools And/or loose stools for three weeks

Earlier presentation and Dx at earlier pathological stage, ↑ 5-yr survival

Fewer complications due to ↓ emergency surgery

Page 4: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Compare ‘standard’ pre-campaign (2011)cohort with a post campaign cohort (2012) for:

Adjusted Dukes’ stage

Intent of first treatment

The proportion of urgent/emergent surgeries

Page 5: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Pre-campaign 2011 cohort: n=155 Post-campaign 2012 cohort: n=125

Case ascertainment; prospectively maintained database of known colorectal cancers within Northumbria TrustSJM

Data collected: Patient age; date of Dx; date and intent first definitive treatment; type and urgency of operation; CT, MRI and histology reports

Radiology and pathology reports interpreted and cross referenced with database information

Page 6: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Adjusted Dukes’ Stagen=279 (1 exclusion)◦ 4 patients R0 at polypectomy◦ Dukes NoS = no metastases, no resection

8/155 patients 2011 cohort 8/124 patients 2012 cohort

◦ Discussion over metastatic status 2011 cohort

16/155 no metastases 10/155 metastases

2012 cohort 10/124 no metastases 8/124 metastases

Page 7: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Adjusted Dukes’ Stage

Page 8: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Intent of First Treatment

Intent of First

Treatment2011 Cohort 2012 Cohort

No. Patients

% Patients No. Patients

% Patients

Definitive 125 87.1 106 84.8

Palliative 17 11 19 15.2

Unknown 2 1.93 0 0

Total 155 125

Page 9: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Urgency of Formal Resection

10.7%

89.3% 87.2%

12.8%

2011 Cohort 2012 Cohort

Page 10: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Post Campaign cohort:

1. Greater proportion of patients presented as Dukes’ A (24.2%) and Dukes’ B (28.2%)

2. But..also an increase in Duke’s D (18.6%)

3. Fewer patients had definitive treatment

4. Fewer formal resections

5. Higher rate (2.1%) urgent surgery

Page 11: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Dukes’ A and B◦ More vigilant patients?

Raising awareness too late?◦ Long term symptoms advice too late i.e. Dukes’

D

Dukes’ D is a late presentation◦ MORE palliative◦ MORE complications emergency surgery

Page 12: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Inter-observer variability on scan and histology reports

Equivocal language on scans when defining metastases vs. no metastases

Missing patient data: ◦ Tertiary referral◦ Poor scan quality◦ Incidental finding at colonoscopy so no pre-

imaging

Page 13: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Re-audit following the national 2013 campaign

Encourage patients to seek advice on first notice of symptoms

Raise awareness of survival rates

Page 14: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer

Cancer Research UK. Cancer mortality for common cancers. [Online] 03 November 2011. http://www.cancerresearchuk.org/cancer-info/cancerstats/mortality/cancer/deaths/uk-cancer-mortality-statistics-for-common-cancers

Department of Health. Government launches its first ever national bowel cancer campaign. [Online] 30 January 2012. http://www.dh.gov.uk/health/2012/01/bowel-cancer-campaign/.

Improving Outcomes: A Strategy for Cancer. s.l. : Department of Health, 2011.

Miss Sarah Mills Mr Mike Bradburn Michele Waimsley-Tonks

Page 15: The Effect of the ‘Be Clear on Cancer’ Campaign on Stage at Presentation of Colorectal Cancer