The Endocrine System Hormone Review Growth Hormone TSH ACTH FSH LH PRL Cortisol glucocorticoids Aldosterone mineralcorticoids DHEA Estrogen Progesterone Testosterone androgens TH!!!! Cortisol Aldosterone DHEA Estrogen Progesterone Testosterone Androgens FSH/ LH/ PRL Oxytocin DHEA Estrogen/ Progesterone Testosterone GnRH GHRH and all other RH TSH ACTH FSH LH PRL Calcitonin PTH Why is calcium so important to keep balanced? Muscle function Nervous system function Bones Glucocorticoids Cortisol Mineralcorticoids Aldosterone Epinephrine Norepinephrine Cortisol Glucagon Epinephrine and Norepinephrine TH Growth Hormone What is gluconeogenesis? Glycogenolysis? Oxytocin ADH Epinephrine Norepinephrine Melatonin Cushings Disease Excess cortisol Diabetes insipidus Deficient ADH Diabetes mellitus Insulin deficiency Graves Disease Excess TH Addisons Disease Excess glucocorticoids, mineralcorticoids, and DHEA Goiter Adequate TH, Missing iodine Dopamine Norepinephrine Melanocyte-stimulating hormone directly onto their target cell into the cerebrospinal fluid into ducts into the blood whether the hormonal molecule is hydrophobic or hydrophilic its size whether it is rapid acting or slow acting if it activates gene activity or not inside the target cell on the plasma membrane of the target cell in the blood plasma in the extracellular fluid depolarization direct gene activation a second messenger endocytosis they are not important signal molecules. small concentrations of hormone can activate many intracellular signals via amplification. they are continuously released from the gland. neurotransmitters also bind to hormone receptors. cAMP Ca 2+ cGMP All of the above a receptor a second messenger the hormone a chaperone failure of the gland to produce the hormone insensitivity of the target cell to the hormone overproduction of the hormone by the gland All of the above are common disorders. humoral neural hormonal negative feedback humoral neural hormonal negative feedback humoral neural hormonal negative feedback humoral neural hormonal negative feedback hyposecretion of oxytocin hypersecretion of oxytocin hyposecretion of ADH hypersecretion of ADH calcitonin Triiodothyronine (T3) Thyroxine (T4) all of the above hypothyroidism cretinism hyperthyroidism hypersecretion of calcitonin catecholamines. mineralocorticoids. glucocorticoids. gonadocorticoids. Cortisol DHEA Aldosterone Epinephrine PTH; calcitonin Thyroid hormones; calmodulin Calcitonin; PTH Calcitonin; thyroid hormone cortisol aldosterone ACTH androgens adrenal medulla adrenal cortex zona glomerulosa zona reticularis estrogen testosterone thyroid hormones melatonin Stomach Heart Kidney Skin