the future of science education – a national effort targeting freshmen & sophomores
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The Future of Science Education – A National Effort Targeting Freshmen & Sophomores. Tuajuanda Jordan Howard Hughes Medical Institute ASMCUE Endicott College May 30 – June 1, 2008. The Science Education Alliance. Mission: To be a national resource for science education by - PowerPoint PPT PresentationTRANSCRIPT
The Future of Science Education –A National Effort Targeting Freshmen
& Sophomores
Tuajuanda JordanHoward Hughes Medical Institute
ASMCUEEndicott CollegeMay 30 – June 1, 2008
ASMCUE 2008
The Science Education Alliance
Mission: To be a national resource for science education by
Developing and providing new materials and methods to the education community
Assembling and supporting educator networks engaged in common activities
ASMCUE 2008
The Ultimate Goal
Improve the production and quality of 21st-century scientists
EDUCATIONR
ESEARCH
ASMCUE 2008
National Genomics Research Initiative – What is it?
An authentic research experience
A collaborative enterprise targeting novice undergraduate scientists
A discovery-based genomics initiative that guides the novice from organism isolation through genome annotation
A partnershipS
cien
ce
ed
uca
tors
Lead scientist
Institutions
HH
MI
ASMCUE 2008
The National Genomics Research Initiative – What are the goals?
Give students experience in genomics research in a supportive and dynamic learning environment
Empower students and faculty
Process of doing science
Tools
Real data worthy of dissemination
Foster local and national collaborations
Students
Students and faculty
Faculty members
ASMCUE 2008
The NGRI PGRI
Why bacteriophage? Plentifula
Highly diverse
Easily isolated directly from the environment
Relatively simple and small genomes
Lead scientist HHMI Professor Established outreach program
Well established techniques to
Isolate, propagate, purify, and visualize the phage
Isolate, purify, clone, and characterize the DNAaHatfull GF, et al 2006
ASMCUE 2008
The PGRI - Why underclassmen?
Freshmen / Sophomores
Early engagement in mentored
research
Encounter research results in upper-level (converted)
coursework
Increased #s pursuing advanced degrees and careers in biomedical science
Increased production & quality of biomedical
scientists
ASMCUE 2008
The PGRI – How does it work?
Part I: in situ -
Part II: transition -
Part III: in silico
Phage DNA
Whole genome sequencingDraft assemblies to students
Aug/Sept
Apr./May
Jan.Nov.
Jan.
Early Nov.
Genome finishingRaw sequences
Finished sequences to students
Mar.Jan.
Genome sequences Genome annotation GenBank
submission?
Collect soil
Isolate, characterize, & purify phage
EMIsolate & purify DNA
Preliminary DNA characterization
Send phage to sequencing center
- Lead scientist poses the question of the year.
ASMCUE 2008
Sci
en
ce e
du
cato
rs
Lead scientist
Institutions
HH
MI
The PGRI – Roles & Responsibilities
ASMCUE 2008
The PGRI – Roles and Responsibilities
Lead Scientist
Provides scientific direction and expertise
Takes lead in data analysis and assessment of scientific significance and impact
Primary author on publications
Science Educator (Faculty)
Provides novice students
Oversees student direction
Ensures accuracy and integrity of student-generated data
Writes draft manuscript
HHMI
Faculty training
Experimental methods, supplies, and resources
Curriculum materials
Community-building activities and resources
Assessment resources and metrics
Networking and dissemination venue
Participating institutions
Provide faculty with time and resources to design and implement course
Assist HHMI in program assessment
ASMCUE 2008
Fall 2008 Cohort Institutions
Oregon State University
University of California, Santa Cruz
University of California, San Diego
Hope College University of Maryland, Baltimore County
University of Louisiana at Monroe
Spelman College
College of William and Mary
Carnegie Mellon University
Washington University at St. Louis
James Madison University
University of Mary Washington
ASMCUE 2008
Genomics Education
National Experiments
ASMCUE 2008
National Experiments
Genomics Education
Harnessing the energy of a major un-tapped resource to answer questions of scientific interest
ASMCUE 2008
Genomics Education
National Experiments : The PGRI
A lead scientist poses a question of scientific interest
A national network of college freshmen work to address the question
Local faculty guide these novice researchers through the process of doing science
HHMI provides the resources to implement and carry out the experience
The novice researchers gain practical experience in microbiology, molecular biology, electron microscopy, and bioinformatics
ASMCUE 2008
The National Genomics Research Initiative
Queries about the NGRI or the SEA
Applications
www.hhmi.org/sea
Reference
Hatfull GF, Pedulla ML, Jacobs-Sera D, Cichon PM, Foley A, et al. (2006) Exploring the Mycobacteriophage Metaproteome: Phage Genomics as an Educational Platform. PLoS Genetics 2(6): e92 doi:10.1371/journal.pgen.0020092