the gut microbiota for health newsletter #65 - esnm: …€¦ · the gut microbiota for health...

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View this email in your browser The Gut Microbiota For Health Newsletter #65 September 3, 2015 Join us Edito Dear Friends, This week we offer you our newest "best of GMFH" document -- this one covering the gut microbiota in inflammatory bowel disease (IBD). The document is a selection of content from our website, compiled and edited by Prof. Philippe Marteau and Prof. Harry Sokol and produced in partnership with the European Crohn’s and Colitis Organisation (ECCO-IBD). This week we also feature two articles covering the recent Chinese study on dietary modulation of gut microbiota to treat genetic and simple obesity in children. First, we summarize the paper in a GMFH selection, and then we speak with Dr. Liping Zhao to learn more about the bacterial 'guilds' discussed in the paper. Highlighted literature selections this week include three papers on the gut-brain axis, and a commentary by Prof. Patrice Cani on dietary emulsifiers and how they impact gut microbiota and gut barrier function. September brings the start of many routines - don't forget to check GMFH on a regular basis to stay informed of what's happening in the field of gut microbiota worldwide! The GMFH publishing team

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The Gut Microbiota For Health Newsletter #65September 3, 2015

Join us

Edito

Dear Friends,

This week we offer you our newest "best of GMFH" document -- this one covering the gutmicrobiota in inflammatory bowel disease (IBD). The document is a selection of contentfrom our website, compiled and edited by Prof. Philippe Marteau and Prof. Harry Sokol andproduced in partnership with the European Crohn’s and Colitis Organisation (ECCO-IBD).

This week we also feature two articles covering the recent Chinese study on dietarymodulation of gut microbiota to treat genetic and simple obesity in children. First, wesummarize the paper in a GMFH selection, and then we speak with Dr. Liping Zhao tolearn more about the bacterial 'guilds' discussed in the paper.

Highlighted literature selections this week include three papers on the gut-brain axis, and acommentary by Prof. Patrice Cani on dietary emulsifiers and how they impact gutmicrobiota and gut barrier function.

September brings the start of many routines - don't forget to check GMFH on a regularbasis to stay informed of what's happening in the field of gut microbiota worldwide!

The GMFH publishing team

Gut microbiota and inflammatorybowel disease: A selection ofcontent from the Gut Microbiota forHealth Experts Exchange 2014-2015

We are pleased to introduce the second editionof our « Best of » series!

This edition is a summary of the latest scientificresearch on the gut microbiota and inflammatorybowel disease (IBD). It is a selection of contentfrom the ESNM's Gut Microbiota for Healthwebsite, compiled and edited by Prof. PhilippeMarteau and Prof. Harry Sokol, in partnershipwith the European Crohn’s and Colitis Organisation.

In this document, you’ll have a picture of how probiotics, genes, the immune system,the intestinal microbiota, and environmental triggers might interact in the onset andcourse of IBD in both adult and pediatric populations.

We invite you to take a look and participate in the related discussion on our LinkedIngroup: linkedin.com/grp/home?gid=4825357

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Written by P. Enck

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Chinese research shows diet can altergut microbiota to treat obesity

A recent study lent insight into the role of the microbiotain both diet-related and genetic obesity in humans.

This Chinese study, led by Prof. Liping Zhao, Prof. AihuaYin, and Prof. Huiru Tang, involved 17 children withPrader-Willi syndrome (PWS) -- the most commongenetic cause of morbid obesity in children -- and 21with simple (diet-induced) obesity.

The children received an intensive dietary intervention ina hospital setting. The diet, aimed at changing the gutmicrobiota, included a high intake of whole grains,traditional Chinese medicinal foods and prebiotics.

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Written by K. Campbell

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Evidence for bacterial 'guilds' in the gutecosystem

Liping Zhao and colleagues, in their recent paper on adietary intervention for simple and genetic obesity,discussed evidence for the existence of gut microbiota'guilds': bacterial genomes within the gut ecosystem thatresponded to the dietary intervention as a group.

Prof. Zhao further explains to GMFH editors, "Guilds arefunctional groups formed by different species in anecosystem. Members in the same guild co-thrive or co-decline together."

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Written by K. Campbell

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The gut-brain axis: A two-way street

A study by De Palma, et al. used germ-free and specificpathogen-free mouse models to investigate the effectsof early-life stress. Researchers reported that stress(maternal separation) altered the hypothalamic-pituitary-adrenal axis in mice. Colonizing adult germ-free micewith the same microbiota led to distinct microbial profilesin mice who had experienced early-life stress. Aftercolonization, behaviour was altered in the stressed micebut not in control mice.

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Written by P. Enck

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The impact of dietary emulsifiers on gutmicrobiota and gut barrier function

A recent study (Chassaing, et al.) showed that twodietary emulsifiers -- carboxymethylcellulose andpolysorbate-80 -- induced gut microbiota alteration andgut barrier dysfunction in mice, resulting in weight gain,low-grade inflammation, and metabolic disorders.

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Written by P. Cani

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The « Gut microbiota e-learning », made available ongutmicrobiotaforheath.com and organized by the GutMicrobiota & Health ESNM Section, is accredited bythe European Accreditation Council for ContinuingMedical Education (EACCME) to provide thefollowing CME activity for medical specialists.

The « Gut microbiota e-learning », made available ongutmicrobiotaforheath.com and organized by the GutMicrobiota & Health ESNM Section, is awarded 1European CME credits (ECMEC's).

Each medical specialist should claim only those credits that he/she actually spent inthe educational activity. The EACCME is an institution of the European Union ofMedical Specialists (UEMS). Only those e-learning materials that are displayed onthe UEMS- EACCME website have formally been accredited.

Take the questionnaire & get CME Credits here

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The Best of the Gut Summit is Online!

The Gut Microbiota For Health Experts Exchange is a medium to share news, innovation and information betweenexperts on the topics of Gut Microbiota for Health.

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Gut microbiota e-learning: Get CME Credits!